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356 results on '"Arai, Taeang"'

1. ALBI score predicts morphological changes in esophageal varices following direct-acting antiviral-induced sustained virological response in patients with liver cirrhosis

Author

Atsukawa, Masanori, Tsubota, Akihito, Kondo, Chisa, Toyoda, Hidenori, Takaguchi, Koichi, Nakamuta, Makoto, Watanabe, Tsunamasa, Morishita, Asahiro, Tani, Joji, Okubo, Hironao, Hiraoka, Atsushi, Nozaki, Akito, Chuma, Makoto, Kawata, Kazuhito, Uojima, Haruki, Ogawa, Chikara, Asano, Toru, Mikami, Shigeru, Kato, Keizo, Matsuura, Kentaro, Ikegami, Tadashi, Ishikawa, Toru, Tsuji, Kunihiko, Tada, Toshifumi, Tsutsui, Akemi, Senoh, Tomonori, Kitamura, Michika, Okubo, Tomomi, Arai, Taeang, Kohjima, Motoyuki, Morita, Kiyoshi, Akahane, Takehiro, Nishikawa, Hiroki, Iwasa, Motoh, Tanaka, Yasuhito, and Iwakiri, Katsuhiko

Published
2024
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2. Efficacy and safety of atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma patients with esophageal–gastric varices

Author

Tada, Fujimasa, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Naganuma, Atsushi, Kosaka, Hisashi, Matono, Tomomitsu, Kuroda, Hidekatsu, Yata, Yutaka, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Yokohama, Keisuke, Nishikawa, Hiroki, Imai, Michitaka, Koizumi, Yohei, Nakamura, Shinichiro, Iijima, Hiroko, Kaibori, Masaki, Hiasa, Yoichi, and Kumada, Takashi

Published
2023
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3. Survival outcomes from atezolizumab plus bevacizumab versus Lenvatinib in Child Pugh B unresectable hepatocellular carcinoma patients

Author

Rimini, Margherita, Persano, Mara, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Salani, Francesca, Lonardi, Sara, Piscaglia, Fabio, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Schirripa, Marta, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Burgio, Valentina, Scartozzi, Mario, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2023
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4. Clinical outcomes with atezolizumab plus bevacizumab or lenvatinib in patients with hepatocellular carcinoma: a multicenter real-world study

Author

Persano, Mara, Rimini, Margherita, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Rimassa, Lorenza, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Tovoli, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Pressiani, Tiziana, Kawaguchi, Takumi, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Piscaglia, Fabio, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Iavarone, Massimo, Di Costanzo, Giovanni, Marra, Fabio, Scartozzi, Mario, Tamburini, Emiliano, Cabibbo, Giuseppe, Foschi, Francesco Giuseppe, Silletta, Marianna, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Cammarota, Antonella, Burgio, Valentina, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2023
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5. Accuracy of the Enhanced Liver Fibrosis Test in Patients With Type 2 Diabetes Mellitus and Its Clinical Implications

Author

Arai, Taeang, Takahashi, Hirokazu, Seko, Yuya, Toyoda, Hidenori, Hayashi, Hideki, Yamaguchi, Kanji, Iwaki, Michihiro, Yoneda, Masato, Shima, Toshihide, Fujii, Hideki, Morishita, Asahiro, Kawata, Kazuhito, Tomita, Kengo, Kawanaka, Miwa, Yoshida, Yuichi, Ikegami, Tadashi, Notsumata, Kazuo, Oeda, Satoshi, Atsukawa, Masanori, Kamada, Yoshihiro, Sumida, Yoshio, Fukushima, Hideaki, Miyoshi, Eiji, Aishima, Shinichi, Okanoue, Takeshi, Itoh, Yoshito, and Nakajima, Atsushi

Published
2024
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6. Real-World Data for Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma: How Does Adherence to the IMbrave150 Trial Inclusion Criteria Impact Prognosis?

Author

Rimini, Margherita, Persano, Mara, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Piscaglia, Fabio, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Pressiani, Tiziana, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Burgio, Valentina, Rimassa, Lorenza, Scartozzi, Mario, Cascinu, Stefano, and Casadei-Gardini, Andrea

Published
2023
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7. Risk factors for portopulmonary hypertension in patients with cirrhosis: a prospective, multicenter study

Author

Atsukawa, Masanori, Tsubota, Akihito, Kondo, Chisa, Koyano, Kaori-Shioda, Ishikawa, Toru, Toyoda, Hidenori, Takaguchi, Koichi, Watanabe, Tsunamasa, Matsuura, Kentaro, Ogawa, Chikara, Hiraoka, Atsushi, Okubo, Hironao, Tateyama, Masakuni, Uojima, Haruki, Nozaki, Akito, Chuma, Makoto, Kato, Keizo, Mikami, Shigeru, Tani, Joji, Morishita, Asahiro, Kawata, Kazuhito, Tada, Toshifumi, Furuichi, Yoshihiro, Okubo, Tomomi, Kawano, Tadamichi, Arai, Taeang, Kawabe, Naoto, Kawamura, Naohiro, Ikegami, Tadashi, Nakamuta, Makoto, Shigefuku, Ryuta, Iwasa, Motoh, Tanaka, Yasuhito, Hatano, Masaru, and Iwakiri, Katsuhiko

Published
2023
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8. Development and validation of a modified albumin–bilirubin grade and α-fetoprotein score (mALF score) for hepatocellular carcinoma patients receiving atezolizumab and bevacizumab

Author

Hatanaka, Takeshi, Kakizaki, Satoru, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Shimada, Noritomo, Kawata, Kazuhito, Kosaka, Hisashi, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, and Kumada, Takashi

Published
2023
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9. Sequential therapies after atezolizumab plus bevacizumab or lenvatinib first-line treatments in hepatocellular carcinoma patients

Author

Persano, Mara, Rimini, Margherita, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Tovoli, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Niizeki, Takashi, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Stefanini, Bernardo, Hiraoka, Atsushi, Sho, Takuya, Nishida, Naoshi, Steup, Christoph, Iavarone, Massimo, Di Costanzo, Giovanni, Marra, Fabio, Tamburini, Emiliano, Cabibbo, Giuseppe, Foschi, Francesco Giuseppe, Silletta, Marianna, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Campani, Claudia, Amadeo, Elisabeth, Rossari, Federico, Burgio, Valentina, Cascinu, Stefano, Scartozzi, Mario, and Casadei-Gardini, Andrea

Published
2023
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11. Prognostic impact of C-reactive protein and alpha-fetoprotein in immunotherapy score in hepatocellular carcinoma patients treated with atezolizumab plus bevacizumab: a multicenter retrospective study

Author

Hatanaka, Takeshi, Kakizaki, Satoru, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Shimada, Noritomo, Kawata, Kazuhito, Kosaka, Hisashi, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Joko, Kouji, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, and Kumada, Takashi

Published
2022
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12. Correction to: Development and validation of a modified albumin–bilirubin grade and α-fetoprotein score (mALF score) for hepatocellular carcinoma patients receiving atezolizumab and bevacizumab

Author

Hatanaka, Takeshi, Kakizaki, Satoru, Hiraoka, Atsushi, Tada, Toshifumi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Shimada, Noritomo, Kawata, Kazuhito, Kosaka, Hisashi, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, and Kumada, Takashi

Published
2023
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13. Atezolizumab plus bevacizumab versus lenvatinib for unresectable hepatocellular carcinoma: a large real-life worldwide population

Author

Casadei-Gardini, Andrea, Rimini, Margherita, Tada, Toshifumi, Suda, Goki, Shimose, Shigeo, Kudo, Masatoshi, Cheon, Jaekyung, Finkelmeier, Fabian, Lim, Ho Yeong, Rimassa, Lorenza, Presa, José, Masi, Gianluca, Yoo, Changhoon, Lonardi, Sara, Tovoli, Francesco, Kumada, Takashi, Sakamoto, Naoya, Iwamoto, Hideki, Aoki, Tomoko, Chon, Hong Jae, Himmelsbach, Vera, Pressiani, Tiziana, Montes, Margarida, Vivaldi, Caterina, Soldà, Caterina, Piscaglia, Fabio, Hiraoka, Atsushi, Sho, Takuya, Niizeki, Takashi, Nishida, Naoshi, Steup, Christoph, Iavarone, Massimo, Di Costanzo, Giovanni, Marra, Fabio, Scartozzi, Mario, Tamburini, Emiliano, Cabibbo, Giuseppe, Foschi, Francesco Giuseppe, Silletta, Marianna, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tada, Fujimasa, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Kosaka, Hisashi, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Kaibori, Masaki, Iijima, Hiroko, Hiasa, Yoichi, Burgio, Valentina, Persano, Mara, Della Corte, Angelo, Ratti, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, Cascinu, Stefano, and Cucchetti, Alessandro

Published
2023
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14. WED-273 The performance of the enhanced liver fibrosis test by cardiometabolic risk factors in patients with metabolic dysfunction-associated steatotic liver disease

Author

Kawata, Kazuhito, primary, Takahashi, Hirokazu, additional, Arai, Taeang, additional, Seko, Yuya, additional, Chida, Takeshi, additional, Noritake, Hiedenao, additional, Toyoda, Hidenori, additional, Hayashi, Hideki, additional, Yamaguchi, Kanji, additional, Iwaki, Michihiro, additional, Yoneda, Masato, additional, Shima, Toshihide, additional, Fujii, Hideki, additional, Morishita, Asahiro, additional, Tomita, Kengo, additional, Kawanaka, Miwa, additional, Yoshida, Yuichi, additional, Ikegami, Tadashi, additional, Notsumata, Kazuo, additional, Oeda, Satoshi, additional, Atsukawa, Masanori, additional, Kamada, Yoshihiro, additional, Sumida, Yoshio, additional, Fukushima, Hideaki, additional, Miyoshi, Eiji, additional, Aishima, Shinichi, additional, Okanoue, Takeshi, additional, Itoh, Yoshito, additional, and Nakajima, Atsushi, additional

Published
2024
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15. SAT-236 Efficacy and safety of incretin-based therapies in patients with metabolic dysfunction-associated steatotic liver disease complicated by type 2 diabetes mellitus

Author

Kawano, Tadamichi, primary, Arai, Taeang, additional, Atsukawa, Masanori, additional, Tada, Toshifumi, additional, Oikawa, Tsunekazu, additional, Tsubota, Akihito, additional, Matsuura, Kentaro, additional, Ishikawa, Toru, additional, Abe, Hiroshi, additional, Kato, Keizo, additional, Morishita, Asahiro, additional, Tani, Joji, additional, Okubo, Tomomi, additional, and Iwakiri, Katsuhiko, additional

Published
2024
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16. Misunderstanding of hepatitis C virus (HCV) infection status by non–specialized medical doctors in patients who achieved sustained virologic response to anti-HCV therapy

Author

Toyoda, Hidenori, Yasuda, Satoshi, Moriya, Akio, Itobayashi, Ei, Uojima, Haruki, Watanabe, Tsunamasa, Atsukawa, Masanori, Arai, Taeang, Ishikawa, Toru, Mikami, Shigeru, Hiraoka, Atsushi, Tsuji, Kunihiko, Oikawa, Tsunekazu, Tsubota, Akihito, Nozaki, Akito, Chuma, Makoto, Abe, Hiroshi, Shima, Toshihide, Kumada, Takashi, and Tanaka, Junko

Published
2022
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17. Shorter pruritus period and milder disease stage are associated with response to nalfurafine hydrochloride in patients with chronic liver disease

Author

Kawano, Tadamichi, Atsukawa, Masanori, Tsubota, Akihito, Shimada, Noritomo, Toyoda, Hidenori, Takaguchi, Koichi, Tani, Joji, Morishita, Asahiro, Hiraoka, Atsushi, Mikami, Shigeru, Ishikawa, Toru, Okubo, Hironao, Watanabe, Tsunamasa, Okubo, Tomomi, Arai, Taeang, Hayama, Korenobu, Itokawa, Norio, Kondo, Chisa, and Iwakiri, Katsuhiko

Published
2022
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18. C-reactive protein to albumin ratio predicts survival in patients with unresectable hepatocellular carcinoma treated with lenvatinib

Author

Tada, Toshifumi, Kumada, Takashi, Hiraoka, Atsushi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Aoki, Tomoko, Koizumi, Yohei, Nakamura, Shinichiro, Joko, Kouji, Hiasa, Yoichi, and Kudo, Masatoshi

Published
2022
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19. Beneficial effect of oral semaglutide for type 2 diabetes mellitus in patients with metabolic dysfunction‐associated steatotic liver disease: A prospective, multicentre, observational study.

Author

Arai, Taeang, Atsukawa, Masanori, Tsubota, Akihito, Oikawa, Tsunekazu, Tada, Toshifumi, Matsuura, Kentaro, Ishikawa, Toru, Abe, Hiroshi, Kato, Keizo, Morishita, Asahiro, Tani, Joji, Okubo, Tomomi, Nagao, Mototsugu, Iwabu, Masato, and Iwakiri, Katsuhiko

Subjects
*TYPE 2 diabetes, *HEPATIC fibrosis, *APPETITE loss, *GLYCEMIC control, *SEMAGLUTIDE
Abstract

Aims: To evaluate the efficacy and safety of oral semaglutide for type 2 diabetes mellitus (T2DM) in patients with metabolic dysfunction‐associated steatotic liver disease (MASLD). Materials and Methods: This was a single‐arm, multicentre, prospective study. Among 80 consecutive patients with MASLD and T2DM who newly received oral semaglutide, 70 completed 48‐week oral semaglutide treatment as scheduled and were included in an efficacy analysis. Dose adjustments of oral semaglutide were determined by each physician while monitoring efficacy and adverse events. Results: Significant improvements in body weight, liver enzymes, lipid profile, and glycaemic control were found at 48 weeks compared with baseline values (all p < 0.01). Controlled attenuation parameter values significantly decreased from baseline to 48 weeks (p < 0.01). Changes in alanine aminotransferase concentrations (r = 0.37, p < 0.01) and controlled attenuation parameter values (r = 0.44, p < 0.01) were significantly correlated with changes in body weight. Liver fibrosis markers, such as type IV collagen 7S, Wisteria floribunda agglutinin‐positive Mac‐2‐binding protein, fibrosis‐4 index, and liver stiffness measurement, significantly decreased from baseline to 48 weeks (all p < 0.01). The most common adverse events were Grades 1–2 transient gastrointestinal symptoms, such as nausea (23 patients, 28.8%), dyspepsia (12, 15.0%) and appetite loss (4, 5.0%). Conclusions: Oral semaglutide treatment for T2DM in patients with MASLD leads to an improvement in liver steatosis and injury, surrogate markers of fibrosis, diabetic status, and lipid profile, and reduces body weight. [ABSTRACT FROM AUTHOR]

Published
2024
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20. The Impact of Cirrhosis and History of Hepatocellular Carcinoma on All-Cause Mortality After Eradication of Hepatitis C Virus in Patients With Chronic Hepatitis C

Author

Toyoda, Hidenori, Atsukawa, Masanori, Uojima, Haruki, Nozaki, Akito, Takaguchi, Koichi, Hiraoka, Atsushi, Itobayashi, Ei, Watanabe, Tsunamasa, Matsuura, Kentaro, Shimada, Noritomo, Abe, Hiroshi, Tsuji, Kunihiko, Itokawa, Norio, Mikami, Shigeru, Ishikawa, Toru, Oikawa, Tsunekazu, Yasuda, Satoshi, Chuma, Makoto, Tsutsui, Akemi, Ikeda, Hiroki, Arai, Taeang, Tsubota, Akihito, Kumada, Takashi, Tanaka, Yasuhito, and Tanaka, Junko

Published
2022
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21. Impact of pemafibrate in patients with metabolic dysfunction‐associated steatotic liver disease complicated by dyslipidemia: A single‐arm prospective study

Author

Ono, Hiroki, primary, Atsukawa, Masanori, additional, Tsubota, Akihito, additional, Arai, Taeang, additional, Suzuki, Kenta, additional, Higashi, Tetsuyuki, additional, Kitamura, Michika, additional, Shioda‐Koyano, Kaori, additional, Kawano, Tadamichi, additional, Yoshida, Yuji, additional, Okubo, Tomomi, additional, Hayama, Korenobu, additional, Itokawa, Norio, additional, Kondo, Chisa, additional, Nagao, Mototsugu, additional, Iwabu, Masato, additional, and Iwakiri, Katsuhiko, additional

Published
2024
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23. Mortality in patients with chronic hepatitis B treated with tenofovir or entecavir: A multinational study

Author

Jang, Tyng‐Yuan, primary, Liang, Po‐Cheng, additional, Jun, Dae Won, additional, Jung, Jang Han, additional, Toyoda, Hidenori, additional, Wang, Chih‐Wen, additional, Yuen, Man‐Fung, additional, Cheung, Ka Shing, additional, Yasuda, Satoshi, additional, Kim, Sung Eun, additional, Yoon, Eileen L, additional, An, Jihyun, additional, Enomoto, Masaru, additional, Kozuka, Ritsuzo, additional, Chuma, Makoto, additional, Nozaki, Akito, additional, Ishikawa, Toru, additional, Watanabe, Tsunamasa, additional, Atsukawa, Masanori, additional, Arai, Taeang, additional, Hayama, Korenobu, additional, Ishigami, Masatoshi, additional, Cho, Yong Kyun, additional, Ogawa, Eiichi, additional, Kim, Hyoung Su, additional, Shim, Jae‐Jun, additional, Uojima, Haruki, additional, Jeong, Soung Won, additional, Ahn, Sang Bong, additional, Takaguchi, Koichi, additional, Senoh, Tomonori, additional, Buti, Maria, additional, Vargas‐Accarino i, Elena, additional, Abe, Hiroshi, additional, Takahashi, Hirokazu, additional, Inoue, Kaori, additional, Yeh, Ming‐Lun, additional, Dai, Chia‐Yen, additional, Huang, Jee‐Fu, additional, Huang, Chung‐Feng, additional, Chuang, Wan‐Long, additional, Nguyen, Mindie H, additional, and Yu, Ming‐Lung, additional

Published
2024
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24. Neutrophil–lymphocyte ratio predicts early outcomes in patients with unresectable hepatocellular carcinoma treated with atezolizumab plus bevacizumab: a multicenter analysis

Author

Tada, Toshifumi, Kumada, Takashi, Hiraoka, Atsushi, Hirooka, Masashi, Kariyama, Kazuya, Tani, Joji, Atsukawa, Masanori, Takaguchi, Koichi, Itobayashi, Ei, Fukunishi, Shinya, Tsuji, Kunihiko, Ishikawa, Toru, Tajiri, Kazuto, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Ogawa, Chikara, Nishimura, Takashi, Hatanaka, Takeshi, Kakizaki, Satoru, Shimada, Noritomo, Kawata, Kazuhito, Tanaka, Takaaki, Ohama, Hideko, Nouso, Kazuhiro, Morishita, Asahiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Okubo, Tomomi, Arai, Taeang, Imai, Michitaka, Naganuma, Atsushi, Koizumi, Yohei, Nakamura, Shinichiro, Joko, Kouji, Iijima, Hiroko, and Hiasa, Yoichi

Published
2022
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25. Comparison of six hepatocellular carcinoma prediction models in Japanese patients after sustained virologic response undergoing rigorous surveillance for hepatocellular carcinoma

Author

Toyoda, Hidenori, primary, Tada, Toshifumi, additional, Uojima, Haruki, additional, Nozaki, Akito, additional, Chuma, Makoto, additional, Takaguchi, Koichi, additional, Hiraoka, Atsushi, additional, Abe, Hiroshi, additional, Itobayashi, Ei, additional, Matsuura, Kentaro, additional, Atsukawa, Masanori, additional, Watanabe, Tsunamasa, additional, Shimada, Noritomo, additional, Nakamuta, Makoto, additional, Kojima, Motoyuki, additional, Tsuji, Kunihiko, additional, Mikami, Shigeru, additional, Ishikawa, Toru, additional, Yasuda, Satoshi, additional, Tsutsui, Akemi, additional, Arai, Taeang, additional, Kumada, Takashi, additional, Tanaka, Yasuhito, additional, Tanaka, Junko, additional, and Chayama, Kazuaki, additional

Published
2024
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26. Comparison of the treatment effect between lenvatinib and atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma in pathologically diagnosed metabolic dysfunction–associated steatotic liver disease.

Author

Takahashi, Hirokazu, primary, Koshiyama, Yuichi, additional, Mitsumoto, Yasuhide, additional, Kobayashi, Takashi, additional, Hayashi, Hideki, additional, Arai, Taeang, additional, Sawada, Koji, additional, Nonaka, Michihiro, additional, Nakahara, Takashi, additional, Tomita, Kengo, additional, Ito, Takanori, additional, Notsumata, Kazuo, additional, Seko, Yuya, additional, Fujii, Hideki, additional, Aishima, Shinichi, additional, Yoneda, Masato, additional, Toyoda, Hidenori, additional, Sumida, Yoshio, additional, Nakajima, Atsushi, additional, and Okanoue, Takeshi, additional

Published
2024
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27. Accuracy of the Enhanced Liver Fibrosis Test in Patients With Type 2 Diabetes Mellitus and Its Clinical Implications

Author

Arai, Taeang, primary, Takahashi, Hirokazu, additional, Seko, Yuya, additional, Toyoda, Hidenori, additional, Hayashi, Hideki, additional, Yamaguchi, Kanji, additional, Iwaki, Michihiro, additional, Yoneda, Masato, additional, Shima, Toshihide, additional, Fujii, Hideki, additional, Morishita, Asahiro, additional, Kawata, Kazuhito, additional, Tomita, Kengo, additional, Kawanaka, Miwa, additional, Yoshida, Yuichi, additional, Ikegami, Tadashi, additional, Notsumata, Kazuo, additional, Oeda, Satoshi, additional, Atsukawa, Masanori, additional, Kamada, Yoshihiro, additional, Sumida, Yoshio, additional, Fukushima, Hideaki, additional, Miyoshi, Eiji, additional, Aishima, Shinichi, additional, Okanoue, Takeshi, additional, Itoh, Yoshito, additional, and Nakajima, Atsushi, additional

Published
2023
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28. Liver fibrosis is associated with carotid atherosclerosis in patients with liver biopsy-proven nonalcoholic fatty liver disease

Author

Arai, Taeang, Atsukawa, Masanori, Tsubota, Akihito, Kato, Keizo, Abe, Hiroshi, Ono, Hirotaka, Kawano, Tadamichi, Yoshida, Yuji, Tanabe, Tomohide, Okubo, Tomomi, Hayama, Korenobu, Nakagawa-Iwashita, Ai, Itokawa, Norio, Kondo, Chisa, Kaneko, Keiko, Emoto, Naoya, Nagao, Mototsugu, Inagaki, Kyoko, Fukuda, Izumi, Sugihara, Hitoshi, and Iwakiri, Katsuhiko

Published
2021
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30. Pretreatment gamma‐glutamyl transferase predicts mortality in patients with chronic hepatitis B treated with nucleotide/nucleoside analogs

Author

Jang, Tyng‐Yuan, primary, Liang, Po‐Cheng, additional, Jun, Dae Won, additional, Jung, Jang Han, additional, Toyoda, Hidenori, additional, Wang, Chih‐Wen, additional, Yuen, Man‐Fung, additional, Cheung, Ka Shing, additional, Yasuda, Satoshi, additional, Kim, Sung Eun, additional, Yoon, Eileen L., additional, An, Jihyun, additional, Enomoto, Masaru, additional, Kozuka, Ritsuzo, additional, Chuma, Makoto, additional, Nozaki, Akito, additional, Ishikawa, Toru, additional, Watanabe, Tsunamasa, additional, Atsukawa, Masanori, additional, Arai, Taeang, additional, Hayama, Korenobu, additional, Ishigami, Masatoshi, additional, Cho, Yong Kyun, additional, Ogawa, Eiichi, additional, Kim, Hyoung Su, additional, Shim, Jae‐Jun, additional, Uojima, Haruki, additional, Jeong, Soung Won, additional, Ahn, Sang Bong, additional, Takaguchi, Koichi, additional, Senoh, Tomonori, additional, Buti, Maria, additional, Vargas‐Accarino, Elena, additional, Abe, Hiroshi, additional, Takahashi, Hirokazu, additional, Inoue, Kaori, additional, Huang, Jee‐Fu, additional, Chuang, Wan‐Long, additional, Yeh, Ming‐Lun, additional, Dai, Chia‐Yen, additional, Huang, Chung‐Feng, additional, Nguyen, Mindie H., additional, and Yu, Ming‐Lung, additional

Published
2023
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31. Geriatric nutritional risk index and newly developed scoring system as prognosis prediction for unresectable hepatocellular carcinoma patients treated with lenvatinib

Author

Ohama, Hideko, primary, Hiraoka, Atsushi, additional, Tada, Toshifumi, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Naganuma, Atsushi, additional, Kosaka, Hisashi, additional, Matono, Tomomitsu, additional, Kuroda, Hidekatsu, additional, Yata, Yutaka, additional, Tanaka, Hironori, additional, Nishikawa, Hiroki, additional, Shibata, Hiroshi, additional, Tada, Fujimasa, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Imai, Michitaka, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Iijima, Hiroko, additional, Kaibori, Masaki, additional, Hiasa, Yoichi, additional, and Kumada, Takashi, additional

Published
2023
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32. Clinical usefulness of newly developed prognostic predictive score for atezolizumab plus bevacizumab for hepatocellular carcinoma

Author

Ohama, Hideko, primary, Hiraoka, Atsushi, additional, Tada, Toshifumi, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Hatanaka, Takeshi, additional, Tani, Joji, additional, Takaguchi, Koichi, additional, Atsukawa, Masanori, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Tajiri, Kazuto, additional, Ishikawa, Toru, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Nishimura, Takashi, additional, Ogawa, Chikara, additional, Satoru, Kakizaki, additional, Shimada, Noritomo, additional, Naganuma, Atsushi, additional, Kawata, Kazuhito, additional, Kosaka, Hisashi, additional, Kuroda, Hidekatsu, additional, Matono, Tomomitsu, additional, Yata, Yutaka, additional, Ochi, Hironori, additional, Tada, Fujimasa, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Yokohama, Keisuke, additional, Nishikawa, Hiroki, additional, Imai, Michitaka, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Iijima, Hiroko, additional, Kaibori, Masaki, additional, Hiasa, Yoichi, additional, and Kumada, Takashi, additional

Published
2023
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33. A novel formula used for predicting hepatocellular carcinoma after the achievement of sustained virologic response by direct-acting antivirals in patients with chronic hepatitis C

Author

Yoshida, Yuji, primary, Atsukawa, Masanori, additional, Kondo, Chisa, additional, Kitamura, Michika, additional, Shioda-Koyano, Kaori, additional, Kawano, Tadamichi, additional, Ono, Hiroki, additional, Hayama, Korenobu, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Itokawa, Norio, additional, and Iwakiri, Katsuhiko, additional

Published
2023
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34. Incidence and predictors of esophagogastric varices bleeding in patients with hepatocellular carcinoma in lenvatinib

Author

Iavarone, Massimo, primary, Alimenti, Eleonora, additional, Tada, Toshifumi, additional, Shimose, Shigeo, additional, Suda, Goki, additional, Yoo, Changhoon, additional, Soldà, Caterina, additional, Piscaglia, Fabio, additional, Tosetti, Giulia, additional, Marra, Fabio, additional, Vivaldi, Caterina, additional, Conti, Fabio, additional, Schirripa, Marta, additional, Iwamoto, Hideki, additional, Sho, Takuya, additional, Lee, So Heun, additional, Rizzato, Mario Domenico, additional, Tonnini, Matteo, additional, Rimini, Margherita, additional, Campani, Claudia, additional, Masi, Gianluca, additional, Foschi, Francesco, additional, Bruccoleri, Mariangela, additional, Kawaguchi, Takumi, additional, Kumada, Takashi, additional, Hiraoka, Atsushi, additional, Atsukawa, Masanori, additional, Fukunishi, Shinya, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Kawata, Kazuhito, additional, Tada, Fujimasa, additional, Ohama, Hideko, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Imai, Michitaka, additional, Naganuma, Atsushi, additional, Casadei-Gardini, Andrea, additional, and Lampertico, Pietro, additional

Published
2023
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35. Platelet–lymphocyte ratio predicts survival in patients with hepatocellular carcinoma who receive lenvatinib: an inverse probability weighting analysis

Author

Tada, Toshifumi, Kumada, Takashi, Hiraoka, Atsushi, Michitaka, Kojiro, Atsukawa, Masanori, Hirooka, Masashi, Tsuji, Kunihiko, Ishikawa, Toru, Takaguchi, Koichi, Kariyama, Kazuya, Itobayashi, Ei, Tajiri, Kazuto, Shimada, Noritomo, Shibata, Hiroshi, Ochi, Hironori, Yasuda, Satoshi, Toyoda, Hidenori, Fukunishi, Shinya, Ohama, Hideko, Kawata, Kazuhito, Nakamura, Shinichiro, Nouso, Kazuhiro, Tsutsui, Akemi, Nagano, Takuya, Itokawa, Norio, Hayama, Korenobu, Arai, Taeang, Imai, Michitaka, Joko, Kouji, Koizumi, Yohei, and Hiasa, Yoichi

Published
2021
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36. Usefulness of Tumor Marker Score for Predicting the Prognosis of Hepatocellular Carcinoma Patients Treated with Atezolizumab Plus Bevacizumab: A Multicenter Retrospective Study

Author

Tanaka, Kazunari, primary, Tsuji, Kunihiko, additional, Hiraoka, Atsushi, additional, Tada, Toshifumi, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Naganuma, Atsushi, additional, Kosaka, Hisashi, additional, Matono, Tomomitsu, additional, Kuroda, Hidekatsu, additional, Yata, Yutaka, additional, Ohama, Hideko, additional, Tada, Fujimasa, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Yokohama, Keisuke, additional, Nishikawa, Hiroki, additional, Imai, Michitaka, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Iijima, Hiroko, additional, Kaibori, Masaki, additional, Hiasa, Yoichi, additional, and Kumada, Takashi, additional

Published
2023
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37. How do the 2022 European Society of Cardiology/European Respiratory Society guidelines modify the diagnosis of portopulmonary hypertension in patients with cirrhosis complicated by portal hypertension? A post hoc analysis

Author

Atsukawa, Masanori, primary, Tsubota, Akihito, additional, Tamura, Yuichi, additional, Koyano‐Shioda, Kaori, additional, Kawano, Tadamichi, additional, Okubo, Tomomi, additional, Hayama, Korenobu, additional, Arai, Taeang, additional, Itokawa, Norio, additional, Taniguchi, Yu, additional, Tamura, Yudai, additional, Kondo, Chisa, additional, and Iwakiri, Katsuhiko, additional

Published
2023
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38. Lenvatinib as Second-Line Treatment after Atezolizumab plus Bevacizumab for Unresectable Hepatocellular Carcinoma: Clinical Results Show Importance of Hepatic Reserve Function

Author

Hiraoka, Atsushi, primary, Kumada, Takashi, additional, Tada, Toshifumi, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Naganuma, Atsushi, additional, Kosaka, Hisashi, additional, Matono, Tomomitsu, additional, Kuroda, Hidekatsu, additional, Yata, Yutaka, additional, Ohama, Hideko, additional, Tada, Fujimasa, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Yokohama, Keisuke, additional, Imai, Michitaka, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Iijima, Hiroko, additional, Kaibori, Masaki, additional, and Hiasa, Yoichi, additional

Published
2023
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39. Efficacy of pemafibrate in patients with non-alcoholic fatty liver disease complicated by dyslipidemia: a single-arm prospective study

Author

Ono, Hiroki, primary, Atsukawa, Masanori, additional, Koyano, Kaori, additional, Hasegawa, Yuta, additional, Kawano, Tadamichi, additional, Tanabe, Tomohide, additional, Yoshida, Yuji, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Hayama, Korenobu, additional, Itokawa, Norio, additional, and Iwakiri, Katsuhiko, additional

Published
2023
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40. Impact of oral semaglutide on liver pathology and glucose metabolism in patients with non-alcoholic fatty liver disease complicated by type 2 diabetes mellitus

Author

Kawano, Tadamichi, primary, Atsukawa, Masanori, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Itokawa, Norio, additional, Tsubota, Akihito, additional, Oikawa, Tsunekazu, additional, Ishikawa, Toru, additional, Tada, Toshifumi, additional, Abe, Hiroshi, additional, Kato, Keizo, additional, Tani, Joji, additional, Morishita, Asahiro, additional, Matsuura, Kentaro, additional, and Iwakiri, Katsuhiko, additional

Published
2023
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41. Impact of new ESC/ERS diagnostic criteria for pulmonary hypertension in cirrhotic patients with portal hypertension on the frequency of portopulmonary hypertension

Author

Ono, Hiroki, primary, Atsukawa, Masanori, additional, Koyano, Kaori, additional, Hasegawa, Yuta, additional, Kawano, Tadamichi, additional, Tanabe, Tomohide, additional, Yoshida, Yuji, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Hayama, Korenobu, additional, Itokawa, Norio, additional, and Iwakiri, Katsuhiko, additional

Published
2023
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42. Incidence and risk factors of esophagogastric varices bleeding in patients with advanced hepatocellular carcinoma treated with lenvatinib

Author

Iavarone, Massimo, primary, Alimenti, Eleonora, additional, Tada, Toshifumi, additional, Shigeo, Shimose, additional, Suda, Goki, additional, Yoo, Changhoon, additional, Soldà, Caterina, additional, Piscaglia, Fabio, additional, Gardini, Andrea Casadei, additional, Marra, Fabio, additional, Vivaldi, Caterina, additional, Conti, Fabio, additional, Schirripa, Marta, additional, Iwamoto, Hideki, additional, Sho, Takuya, additional, Leo, So Heun, additional, Rizzato, Mario Domenico, additional, Tonnini, Matteo, additional, Rimini, Margherita, additional, Campani, Claudia, additional, Masi, Gianluca, additional, Foschi, Francesco, additional, Bruccoleri, Mariangela, additional, Kawaguchi, Takumi, additional, Kumada, Takashi, additional, Hiraoka, Atsushi, additional, Atsukawa, Masanori, additional, Fukunishi, Shinya, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Kawata, Kazuhito, additional, Tada, Faujimasa, additional, Ohama, Hideko, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Imai, Michitaka, additional, Naganuma, Atsushi, additional, Tosetti, Giulia, additional, and Lampertico, Pietro, additional

Published
2023
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45. Pretreatment gamma‐glutamyl transferase predicts mortality in patients with chronic hepatitis B treated with nucleotide/nucleoside analogs.

Author

Jang, Tyng‐Yuan, Liang, Po‐Cheng, Jun, Dae Won, Jung, Jang Han, Toyoda, Hidenori, Wang, Chih‐Wen, Yuen, Man‐Fung, Cheung, Ka Shing, Yasuda, Satoshi, Kim, Sung Eun, Yoon, Eileen L., An, Jihyun, Enomoto, Masaru, Kozuka, Ritsuzo, Chuma, Makoto, Nozaki, Akito, Ishikawa, Toru, Watanabe, Tsunamasa, Atsukawa, Masanori, and Arai, Taeang

Subjects
CHRONIC hepatitis B, FATTY liver, ALANINE aminotransferase, MORTALITY, ALCOHOL drinking
Abstract

Elevated serum gamma‐glutamyl transferase (GGT) levels are associated with chronic hepatitis B (CHB)‐related hepatocellular carcinoma. However, their role in predicting mortality in patients with CHB treated with nucleotide/nucleoside analogs (NAs) remains elusive. Altogether, 2843 patients with CHB treated with NAs were recruited from a multinational cohort. Serum GGT levels before and 6 months (Month‐6) after initiating NAs were measured to explore their association with all‐cause, liver‐related, and non‐liver‐related mortality. The annual incidence of all‐cause mortality was 0.9/100 person‐years over a follow‐up period of 17,436.3 person‐years. Compared with patients who survived, those who died had a significantly higher pretreatment (89.3 vs. 67.4 U/L, p = 0.002) and Month‐6‐GGT levels (62.1 vs. 38.4 U/L, p < 0.001). The factors associated with all‐cause mortality included cirrhosis (hazard ratio [HR]/95% confidence interval [CI]: 2.66/1.92–3.70, p < 0.001), pretreatment GGT levels (HR/CI: 1.004/1.003–1.006, p < 0.001), alanine aminotransferase level (HR/CI: 0.996/0.994–0.998, p = 0.001), and age (HR/CI: 1.06/1.04–1.07, p < 0.001). Regarding liver‐related mortality, the independent factors included cirrhosis (HR/CI: 4.36/2.79–6.89, p < 0.001), pretreatment GGT levels (HR/CI: 1.006/1.004–1.008, p < 0.001), alanine aminotransferase level (HR/CI: 0.993/0.990–0.997, p = 0.001), age (HR/CI: 1.03/1.01–1.05, p < 0.001), and fatty liver disease (HR/CI: 0.30/0.15–0.59, p = 0.001). Pretreatment GGT levels were also independently predictive of non‐liver‐related mortality (HR/CI: 1.003/1.000–1.005, p = 0.03). The results remained consistent after excluding the patients with a history of alcohol use. A dose‐dependent manner of <25, 25–75, and >75 percentile of pretreatment GGT levels was observed with respect to the all‐cause mortality (trend p < 0.001). Pretreatment serum GGT levels predicted all‐cause, liver‐related, and non‐liver‐related mortality in patients with CHB treated with NAs. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Association of PPI and antibiotics with the clinical outcomes of HCC patients receiving atezolizumab and bevacizumab: A multicenter analysis

Author

Hatanaka, Takeshi, primary, Kakizaki, Satoru, additional, Hiraoka, Atsushi, additional, Tada, Toshifumi, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Kosaka, Hisashi, additional, Naganuma, Atsushi, additional, Yata, Yutaka, additional, Tanaka, Takaaki, additional, Ohama, Hideko, additional, Tada, Fujimasa, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Imai, Michitaka, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Kaibori, Masaki, additional, Iijima, Hiroko, additional, Hiasa, Yoichi, additional, and Kumada, Takashi, additional

Published
2023
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48. Role of the prognostic nutritional index in predicting survival in advanced hepatocellular carcinoma treated with atezolizumab plus bevacizumab

Author

Rimini, Margherita, primary, Persano, Mara, additional, Tada, Toshifumi, additional, Suda, Goki, additional, Shimose, Shigeo, additional, Kudo, Masatoshi, additional, Cheon, Jaekyung, additional, Finkelmeier, Fabian, additional, Lim, Ho Yeong, additional, Presa Ramos, José, additional, Masi, Gianluca, additional, Yoo, Changhoon, additional, Lonardi, Sara, additional, Stefanini, Bernardo, additional, Kumada, Takashi, additional, Sakamoto, Naoya, additional, Iwamoto, Hideki, additional, Aoki, Tomoko, additional, Chon, Hong Jae, additional, Himmelsbach, Vera, additional, Montes, Margarida, additional, Vivaldi, Caterina, additional, Soldà, Caterina, additional, Hiraoka, Atsushi, additional, Sho, Takuya, additional, Niizeki, Takashi, additional, Nishida, Naoshi, additional, Steup, Christoph, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Tada, Fujimasa, additional, Ohama, Hideko, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Imai, Michitaka, additional, Kosaka, Hisashi, additional, Naganuma, Atsushi, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Kaibori, Masaki, additional, Iijima, Hiroko, additional, Hiasa, Yoichi, additional, Burgio, Valentina, additional, Della Corte, Angelo, additional, Ratti, Francesca, additional, De Cobelli, Francesco, additional, Aldrighetti, Luca, additional, Scartozzi, Mario, additional, Cascinu, Stefano, additional, and Casadei-Gardini, Andrea, additional

Published
2023
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49. Adverse events as potential predictive factors of therapeutic activity in patients with unresectable hepatocellular carcinoma treated with atezolizumab plus bevacizumab

Author

Tada, Toshifumi, primary, Kumada, Takashi, additional, Hiraoka, Atsushi, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Tada, Fujimasa, additional, Ohama, Hideko, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Imai, Michitaka, additional, Kosaka, Hisashi, additional, Naganuma, Atsushi, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Kaibori, Masaki, additional, Iijima, Hiroko, additional, and Hiasa, Yoichi, additional

Published
2022
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50. Clinical outcomes with atezolizumab plus bevacizumab or lenvatinib in patients with hepatocellular carcinoma: a multicenter real-world study

Author

Persano, Mara, primary, Rimini, Margherita, additional, Tada, Toshifumi, additional, Suda, Goki, additional, Shimose, Shigeo, additional, Kudo, Masatoshi, additional, Cheon, Jaekyung, additional, Finkelmeier, Fabian, additional, Lim, Ho Yeong, additional, Rimassa, Lorenza, additional, Presa, José, additional, Masi, Gianluca, additional, Yoo, Changhoon, additional, Lonardi, Sara, additional, Tovoli, Francesco, additional, Kumada, Takashi, additional, Sakamoto, Naoya, additional, Iwamoto, Hideki, additional, Aoki, Tomoko, additional, Chon, Hong Jae, additional, Himmelsbach, Vera, additional, Pressiani, Tiziana, additional, Kawaguchi, Takumi, additional, Montes, Margarida, additional, Vivaldi, Caterina, additional, Soldà, Caterina, additional, Piscaglia, Fabio, additional, Hiraoka, Atsushi, additional, Sho, Takuya, additional, Niizeki, Takashi, additional, Nishida, Naoshi, additional, Steup, Christoph, additional, Iavarone, Massimo, additional, Di Costanzo, Giovanni, additional, Marra, Fabio, additional, Scartozzi, Mario, additional, Tamburini, Emiliano, additional, Cabibbo, Giuseppe, additional, Foschi, Francesco Giuseppe, additional, Silletta, Marianna, additional, Hirooka, Masashi, additional, Kariyama, Kazuya, additional, Tani, Joji, additional, Atsukawa, Masanori, additional, Takaguchi, Koichi, additional, Itobayashi, Ei, additional, Fukunishi, Shinya, additional, Tsuji, Kunihiko, additional, Ishikawa, Toru, additional, Tajiri, Kazuto, additional, Ochi, Hironori, additional, Yasuda, Satoshi, additional, Toyoda, Hidenori, additional, Ogawa, Chikara, additional, Nishimura, Takashi, additional, Hatanaka, Takeshi, additional, Kakizaki, Satoru, additional, Shimada, Noritomo, additional, Kawata, Kazuhito, additional, Tada, Fujimasa, additional, Ohama, Hideko, additional, Nouso, Kazuhiro, additional, Morishita, Asahiro, additional, Tsutsui, Akemi, additional, Nagano, Takuya, additional, Itokawa, Norio, additional, Okubo, Tomomi, additional, Arai, Taeang, additional, Imai, Michitaka, additional, Kosaka, Hisashi, additional, Naganuma, Atsushi, additional, Koizumi, Yohei, additional, Nakamura, Shinichiro, additional, Kaibori, Masaki, additional, Iijima, Hiroko, additional, Hiasa, Yoichi, additional, Cammarota, Antonella, additional, Burgio, Valentina, additional, Cascinu, Stefano, additional, and Casadei-Gardini, Andrea, additional

Published
2022
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