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29 results on '"Aoki, Shun"'

2. Neohesperidin exerts antidepressant-like effect via the mechanistic target of rapamycin complex 1 in the medial prefrontal cortex in male mice

Author

Deyama, Satoshi, Aoki, Shun, Sugie, Rinako, and Kaneda, Katsuyuki

Abstract

Neohesperidin, a citrus flavonoid, shows potential for activating the mechanistic target of rapamycin complex 1 (mTORC1). Here, the antidepressant-like effect of neohesperidin was examined in male ICR mice (naïve mice and mice treated repeatedly with prednisolone, a synthetic glucocorticoid, which induces depression-like behavior). Oral neohesperidin administration exerted an antidepressant-like effect in the forced swim test 1 h post-treatment, in naïve mice; this effect was no longer observed at 24 h. Neohesperidin also reversed prednisolone-induced depression-like behavior. This effect was blocked by infusing rapamycin, an mTORC1 inhibitor, into the medial prefrontal cortex. Neohesperidin may rapidly produce an antidepressant-like effect.

Published
2024
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6. Quantitative Techniques of Ultrasonography in the Assessment of Femoropopliteal Atherosclerotic Lesions Using Peak Systolic Velocity Ratio: Results From the TURN-UP Study

Author

Hayashi, Aiko, primary, Takahara, Mitsuyoshi, additional, Fujihara, Masahiko, additional, Komiya, Yumiko, additional, Aoki, Shun, additional, Enoki, Mina, additional, Miyauchi, Takamitsu, additional, Tanimoto, Rika, additional, Fujisaki, Jun, additional, Ishida, Keisuke, additional, Yamasaki, Masayuki, additional, Waratani, Naoto, additional, Kawaguchi, Harumi, additional, and Yamaoka, Terutoshi, additional

Published
2023
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10. u-Photo: Interacting with Pervasive Services Using Digital Still Images

Author

Suzuki, Genta, Aoki, Shun, Iwamoto, Takeshi, Maruyama, Daisuke, Koda, Takuya, Kohtake, Naohiko, Takashio, Kazunori, Tokuda, Hideyuki, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Gellersen, Hans -W., editor, Want, Roy, editor, and Schmidt, Albrecht, editor

Published
2005
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20. Quantitative Techniques of Ultrasonography in the Assessment of Femoropopliteal Atherosclerotic Lesions Using Peak Systolic Velocity Ratio: Results From the TURN-UP Study

Author

Hayashi, Aiko, Takahara, Mitsuyoshi, Fujihara, Masahiko, Komiya, Yumiko, Aoki, Shun, Enoki, Mina, Miyauchi, Takamitsu, Tanimoto, Rika, Fujisaki, Jun, Ishida, Keisuke, Yamasaki, Masayuki, Waratani, Naoto, Kawaguchi, Harumi, and Yamaoka, Terutoshi

Abstract

Purpose: Duplex ultrasound (DUS)-measured peak systolic velocity ratios (PSVRs) are commonly used to evaluate arterial stenosis in lower extremity artery disease (LEAD). However, these measurement methods have not yet been standardized. This study aimed to reveal the influence of measuring methods on PSVR values.Methods: A 132 femoropopliteal lesions with PSVR ranging from 1.5 to 3.5 evaluated using method A (angle correction 60°, the direction of blood flow, the no or few atherosclerotic changes closest to the lesion proximal side was defined as the nonstenotic area) were included. The following 4 different methods were then compared with method A: method B, angle correction 45°; method C, angle correction 60° measured along the vessel wall; D, angle correction 60°, with the nonstenotic area the lowest peak systolic velocity area; and E, angle correction 60°, with the reference point fixed at 2 cm proximal to the target lesion area. The difference in PSVR values was analyzed using the Bland-Altman method.Results: The mean PSVR value measured by method A was 2.27±0.51, those measured by methods B, C, D, and E were 2.21±0.55, 2.31±0.66, 2.34±0.63, and 2.11±0.63, respectively. The 95% prediction intervals of the differences in PSVR measurements versus A were -0.64 to +0.53 for method B, −0.59 to +0.68 for method C, −0.77 to +0.91 for method D, and −1.12 to +0.79 for method E.Conclusion: PSVR values considerably differed between measuring methods. PSVR values by DUS are largely dependent on the measurement methods, which could considerably affect the judgment of LEAD.Clinical Impact: Due to differences in several DUS measurement methods, the PSVR results could be changed. Therefore, to need further investigations and unification of measurement method.

Published
2024
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27. u-Photo: Interacting with Pervasive Services Using Digital Still Images.

Author

Gellersen, Hans W., Want, Roy, Schmidt, Albrecht, Suzuki, Genta, Aoki, Shun, Iwamoto, Takeshi, Maruyama, Daisuke, Koda, Takuya, Kohtake, Naohiko, Takashio, Kazunori, and Tokuda, Hideyuki

Abstract

This paper presents u-Photo which is an interactive digital still image including information of pervasive services associated with networked appliances and sensors in pervasive computing environment. U-Photo Tools can generate a u-Photo and provide methods for discovering contextual information about these pervasive services. Users can easily find out this information through the metaphor of ‘taking a photograph'; the users use u-Photo by clicking on a physical entity in a digital still image. In addition, u-Photo makes managing information more efficient because the still image has embedded visual information. Using u-Photo and u-Photo Tools, we conducted various demonstrations and performed usability tests. The results of these tests show that u-Photo Tools are easy to learn. We also present that the time that expert u-Photo users take to find the object in piles of u-Photos is shorter than the time it take to find the object in piles of text-based descriptions. [ABSTRACT FROM AUTHOR]

Published
2005
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