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1. Home OCT Imaging for Newly Diagnosed Neovascular Age-Related Macular Degeneration: A Feasibility Study

Author

Glassman, Adam R., Beck, Roy W., Baptista, Alyssa, Beaulieu, Wesley T., Calhoun, Claire T., Constantine, Sharon R., Dale, Brian B., Dupre, Simone S., Franklin, Crystal A., Galusic, Sandra, Huggins, Meagan, Hunter, Brenda L., Johnson, Paula A., Josic, Kristin, Kelly, Brittany, Liu, Danni, Maguire, Maureen G., Meadows, Britney, Melia, Michele, Preston, Carin M., Stockdale, Cynthia R., Zokruah, Alice, Sun, Jennifer K., Martin, Daniel F., Bhargava, Sangeeta, Barkmeier, Andrew J., Baskin, Darrell, Blodi, Barbra, Chew, Emily, Ferris, Frederick L., III, Jaffe, Glenn J., Jampol, Lee M., Jhaveri, Chirag D., MacCumber, Mathew, Maturi, Raj K., Solomon, Sharon D., Antoszyk, Andrew N., Lujan, Brandon, Slahi-Had, Hani, Lane, Richard Gary, Adams, Lydia, Rivera, Rachel R., Nakoski, Brenda, Weeks, Rhonda F., Braverman, Allan L., McDonald-Mueller, Lauren, Stuart, Maria A., Pulliam, Brook G., Boyd, Lynda K., Wehmeier, Jarrod, Schremp, Steve A., Googe, Joseph M., Oliver, Kristina, Walsh, Justin, Asher, Julie, Milstead, Katie, Wheeler, Jeff, Griffone, Hodge A., Blinder, Kevin J., Calhoun, Claire, Mein, Calvin E., Baskin, Darrell E., Vieyra, Gabriela, and Chica, Moises A.

Published
2024
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2. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials

Author

Cole, Abosede O, Gerstenblith, Adam T, Kotagiri, Ajay, Edwards, Albert O, Zambrano, Alberto D, Eaton, Alexander M, Rubowitz, Alexander, Lyon, Alice T, Chiang, Allen, Ho, Allen, Hu, Allen Y, Guerami, Amir H, Dessouki, Amr L, de Carvalho, André Corrêa Maia, Emanuelli, Andrés, Chang, Andrew A, Antoszyk, Andrew N, Francone, Anibal Andrés, Prasad, Anita, Wolf, Armin, Khanani, Arshad M, Abbey, Ashkan Michael, Moulana, Asma, Wihelm, Barbara, Sikorski, Bartosz L, Kuppermann, Baruch D, Wolff, Benjamin, Jewart, Brian H, Do, Brian K, Chan-Kai, Brian T, Mein, Calvin, Hoyng, Carel B, Awh, Carl C, Regillio, Carl, Zeolite, Carlos, Baumal, Caroline R, Creuzot-Garcher, Catherine, Maury, Catherine Français, Wykoff, Charles C, Newell, Charles K, Jhaveri, Chirag, Lohmann, Chris P, Dinah, Christiana B, Ma, Colin, Crawford, Courtney, Parke, D Wilkin, Lavinsky, Daniel, Roth, Daniel, Pieramici, Dante J, Moshfeghi, Darius M, Levin, Darrin, Saperstein, David A, Brown, David, Gaucher, David, Lally, David R, Liao, David S, Brown, David Warren, Goldstein, Debra, Marcus, Dennis, Chan, Derek G, Dhoot, Dilsher, Tacite, Domingo, Zalewski, Dominik, Espana, Edgar M, Lad, Eleonora M, Souied, Eric H, Suan, Eric P, Eting, Eva, Sola, Federico Furno, de Bats, Flore, Bandello, Francesco, Gómez-Ulla, Francisco, Devin, François, Holz, Frank G, Chen, Fred K, Makkouk, Fuad, Dyer, Gawain, Spital, George, Staurenghi, Giovanni, Stoller, Glenn, Cousins, Gwen, Salehi-Had, Hani, Agostini, Hansjürgen, Eleftheriadis, Haralabos, Weiss, Harold, Sultan, Harris C, Massé, Hélène, Pearce, Ian, Dias, Indra, Barbazetto, Irene, Rosenblatt, Irit, Suñer, Ivan J, Kovach, Jaclyn L, Kaluzny, Jakub, Borthwick, James, Howard, James G, Wong, James, Ernest, Jan, Němčanský, Jan, Ysasaga, Jason Edward, Handza, Jason M, Moreno, Javier Antonio Montero, Korobelnik, Jean-François, Heier, Jeffrey S, Arnold, Jennifer J, Brown, Jeremiah, Bafalluy, Joaquin, Pearlman, Joel, Pitcher, John D, Kitchens, John, Carlson, John P, Gilhotra, Jolly, Fein, Jordana, Monés, Jordi M, Luna, José Domingo, Moreno, José María Ruiz, Coney, Joseph M, Sallum, Juliana Maria Ferraz, Olsen, Karl R, Blobner, Katharina, Macoul, Katherine A, Oh, Kean T, Malik, Khurram Javed, Hattenbach, Lars-Olof, Kodjikian, Laurent, Neto, Laurentino Biccas, Singerman, Lawrence J, Altay, Lebriz, Sheck, Leo-H, Feiner, Leonard, Harris, Lindsey D, Chishold, Lionel D, Rao, Llewelyn J, Nehemy, Márcio Bittar, Elizalde, Maria Jose Capella, Gamulescu, Maria-Andreea, Saravia, Mario J, Johnson, Mark W, McKibbin, Martin, Maccumber, Mathew, Vidosevich, Matko, Ohr, Matthew P, Samuel, Michael A, Singer, Michael A, Cassell, Michael, Dollin, Michael, Elman, Michael J, Ip, Michael S, Goldstein, Michaella, Busquets, Miguel, Mititelu, Mihai, Shah, Milan, Veith, Miroslav, Fineman, Mitchell, Varano, Monica, Christmas, Nancy, Steinle, Nathan C, Chaudhry, Nauman, Chinskey, Nicholas D, Eter, Nicole, London, Nikolas J S, Mathalone, Nurit, Schlottmann, Patricio G, Coady, Patrick, Higgins, Patrick M, Raskauskas, Paul A, Yates, Paul A, Bernstein, Paul, Mitchell, Paul, Monsour, Paul, Raphaelian, Paul V, Stanga, Paulo E, Stodulka, Pavel, Issa, Peter Charbel, Pavan, Peter, Ferrone, Phil J, Oleksy, Piotr, Abraham, Prema, Mruthyunjaya, Prithvi, Nguyen, Quan Dong, Reddy, Rahul K, Khurana, Rahul N, Tuli, Raman, Tadayoni, Ramin, Katz, Randy Steven, Arora, Rashi, Schlingemann, Reinier O, Rosen, Richard B, Gale, Richard, Scartozzi, Richard, Isernharge, Ricky, Singh, Rishi P, Stoltz, Robert A, Avery, Robert L, Wirthlin, Robert S, Guymer, Robyn, Goldberg, Roger A, Frenkel, Ronald, Belfort, Rubens Jr, Mohand-Said, Saddek, Grisanti, Salvatore, Razavi, Sam, Fraser-Bell, Samantha, Shah, Sandeep N, Wickremasinghe, Sanjeewa, Haug, Sara Joy, Adrean, Sean D, Priglinger, Siegfried G, Esposti, Simona Degli, Guest, Stephen, Huddleston, Stephen, Itty, Sujit, Moon, Suk Jin, Bhatia, Sumit P, Gupta, Sunil, Patel, Sunil S, Garg, Sunir J, Joshi, Sunir, Nghiem-Buffet, Sylvia, Johnson, T Mark, Jaouni, Tareq, Ach, Thomas, Williams, Thomas R, Sheidow, Thomas, Cleland, Timothy P, You, Timothy T, Peto, Tunde, Konidaris, Vasileios, Gonzalez, Victor H, Korda, Vladimir, Freeman, William R, Bridges, William Z, Barak, Yoreh, Zagorski, Zbigniew, Yehoshua, Zohar, Dubska, Zora, Rosenfeld, Philip J, Guymer, Robyn H, Boyer, David, Grossi, Federico, Korobelnik, Jean-Francois, Slakter, Jason S, Waheed, Nadia K, Metlapally, Ravi, Steinle, Nathan, Francone, Anibal A, Hu, Allen, Deschatelets, Pascal, Francois, Cedric, Bliss, Caleb, Monés, Jordi, and Ribeiro, Ramiro

Published
2023
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3. Prediction for 2-Year Vision Outcomes Using Early Morphologic and Functional Responses in the Comparison of Age-related Macular Degeneration Treatments Trials

Author

Williams, David F., Beardsley, Sara, Bennett, Steven, Cantrill, Herbert, Chan-Tram, Carmen, Cheshier, Holly, Damato, Kathyrn, Davies, John, Dev, Sundeep, Enloe, Julianne, Follano, Gennaro, Gilbert, Peggy, Johnson, Jill, Jones, Tori, Mayleben, Lisa, Mittra, Robert, Moos, Martha, Neist, Ryan, Oestreich, Neal, Quiram, Polly, Ramsay, Robert, Ryan, Edwin, Schindeldecker, Stephanie, Snater, John, Steele, Trenise, Selders, Dwight, Tonsfeldt, Jessica, Valardi, Shelly, Fish, Gary Edd, Aguado, Hank A., Arceneaux, Sally, Arnwine, Jean, Bell, Kim, Bell, Tina, Boleman, Bob, Bradley, Patricia, Callanan, David, Coors, Lori, Creighton, Jodi, Crew, Timothy, Cummings, Kimberly, Dock, Christopher, Duignan, Karen, Fuller, Dwain, Gray, Keith, Hendrix, Betsy, Hesse, Nicholas, Jaramillo, Diana, Jost, Bradley, Lash, Sandy, Lonsdale, Laura, Mackens, Michael, Mutz, Karin, Potts, Michael, Sanchez, Brenda, Snyder, William, Solley, Wayne, Tarter, Carrie, Wang, Robert, Williams, Patrick, Perkins, Stephen L., Anderson, Nicholas, Arnold, Ann, Blais, Paul, Googe, Joseph, Higdon, Tina T., Hunt, Cecile, Johnson, Mary, Miller, James, Moore, Misty, Morris, Charity K., Morris, Christopher, Oelrich, Sarah, Oliver, Kristina, Seitz, Vicky, Whetstone, Jerry, Doft, Bernard H., Bedel, Jay, Bergren, Robert, Borthwick, Ann, Conrad, Paul, Fec, Amanda, Fulwylie, Christina, Ingram, Willia, Latham, Shawnique, Lester, Gina, Liu, Judy, Lobes, Louis, Lucko, Nicole M., Mechling, Holly, Merlotti, Lori, McBroom, Keith, Olsen, Karl, Puskas, Danielle, Rath, Pamela, Schmucker, Maria, Schueckler, Lynn, Schultz, Christina, Shultz, Heather, Steinberg, David, Vyas, Avni, Whale, Kim, Yeckel, Kimberly, Orth, David H., Arredondo, Linda S., Brown, Susan, Ciscato, Barbara J., Civantos, Joseph M., Figliulo, Celeste, Hasan, Sohail, Kosinski, Belinda, Muir, Dan, Nelson, Kiersten, Packo, Kirk, Pollack, John S., Rezaei, Kourous, Shelton, Gina, Townsend-Patrick, Shannya, Walsh, Marian, McDonald, H. Richard, Ansari, Nina, Bye, Amanda, Fu, Arthur D., Grout, Sean, Indermill, Chad, Johnson, Robert N., Jumper, J. Michael, Linares, Silvia, Lujan, Brandon J., Munden, Ames, Persons, Meredith, Rodriguez, Rosa, Rose, Jennifer M., Teske, Brandi, Urias, Yesmin, Young, Stephen, Dreyer, Richard F., Daniel, Howard, Connaughton, Michele, Handelman, Irvin, Hobbs, Stephen, Hoerner, Christine, Hudson, Dawn, Kopfer, Marcia, Lee, Michael, Lemley, Craig, Logan, Joe, Ma, Colin, Mallet, Christophe, Milliron, Amanda, Peters, Mark, Wohlsein, Harry, Pearlman, Joel A., Andrews, Margo, Bartlett, Melissa, Carlson, Nanette, Cox, Emily, Equi, Robert, Gonzalez, Marta, Griffin, Sophia, Hogue, Fran, Kennedy, Lance, Kryuchkov, Lana, Lopez, Carmen, Lopez, Danny, Luevano, Bertha, McKenna, Erin, Patel, Arun, Reed, Brian, Secor, Nyla, Sison, Iris R., Tsai, Tony, Varghis, Nina, Waller, Brooke, Wendel, Robert, Yebra, Reina, Roth, Daniel B., Deinzer, Jane, Fine, Howard, Green, Flory, Green, Stuart, Keyser, Bruce, Leff, Steven, Leviton, Amy, Martir, Amy, Mosenthine, Kristin, Muscle, Starr, Okoren, Linda, Parker, Sandy, Prenner, Jonathan, Price, Nancy, Rogers, Deana, Rosas, Linda, Schlosser, Alex, Studenko, Loretta, Tantum, Thea, Wheatley, Harold, Trese, Michael T., Aaberg, Thomas, Bezaire, Denis, Bridges, Craig, Bryant, Doug, Capone, Antonio, Coleman, Michelle, Consolo, Christina, Cook, Cindy, DuLong, Candice, Garretson, Bruce, Grooten, Tracy, Hammersley, Julie, Hassan, Tarek, Jessick, Heather, Jones, Nanette, Kinsman, Crystal, Krumlauf, Jennifer, Lewis, Sandy, Locke, Heather, Margherio, Alan, Markus, Debra, Marsh, Tanya, Neal, Serena, Noffke, Amy, Oh, Kean, Pence, Clarence, Preston, Lisa, Raphaelian, Paul, Regan, Virginia R., Roberts, Peter, Ruby, Alan, Sarrafizadeh, Ramin, Scherf, Marissa, Scott, Sarita, Sneed, Scott, Staples, Lisa, Terry, Brad, Trese, Matthew T., Videtich, Joan, Williams, George, Zajechowski, Mary, Joseph, Daniel P., Blinder, Kevin, Boyd, Lynda, Buckley, Sarah, Crow, Meaghan, Dinatale, Amanda, Engelbrecht, Nicholas, Forke, Bridget, Gabel, Dana, Grand, Gilbert, Grillion-Cerone, Jennifer, Holekamp, Nancy, Kelly, Charlotte, Nobel, Ginny, Pepple, Kelly, Raeber, Matt, Rao, P. Kumar, Ressel, Tammy, Schremp, Steven, Sgorlon, Merrilee, Shears, Shantia, Thomas, Matthew, Timma, Cathy, Vaughn, Annette, Walters, Carolyn, Weeks, Rhonda, Wehmeier, Jarrod, Wright, Tim, Berinstein, Daniel M., Ayyad, Aida, Barazi, Mohammed K., Bickhart, Erica, Brady, Tracey, Byank, Lisa, Cronise, Alysia, Denny, Vanessa, Dunn, Courtney, Flory, Michael, Frantz, Robert, Garfinkel, Richard A., Gilbert, William, Lai, Michael M., Melamud, Alexander, Newgen, Janine, Newton, Shamekia, Oliver, Debbie, Osman, Michael, Sanders, Reginald, von Fricken, Manfred, Dugel, Pravin, Arenas, Sandra, Balea, Gabe, Bartoli, Dayna, Bucci, John, Cornelius, Jennifer A., Dickens, Scheleen, Doherty, Don, Dunlap, Heather, Goldenberg, David, Jamal, Karim, Jimenez, Norma, Kavanagh, Nicole, Kunimoto, Derek, Martin, John, Miner, Jessica, Mobley, Sarah, Park, Donald, Quinlan, Edward, Sipperley, Jack, Slagle, Carol, Smith, Danielle, Yafchak, Miguelina, Yager, Rohana, Flaxel, Christina J., Bailey, Steven, Francis, Peter, Howell, Chris, Hwang, Thomas, Ira, Shirley, Klein, Michael, Lauer, Andreas, Liesegang, Teresa, Lundquist, Ann, Nolte, Sarah, Nolte, Susan K., Pickell, Scott, Pope, Susan, Rossi, Joseph, Schain, Mitchell, Steinkamp, Peter, Toomey, Maureen D., Vahrenwald, Debora, West, Kelly, Hubbard, Baker, Andelman, Stacey, Bergstrom, Chris, Brower, Judy, Cribbs, Blaine, Curtis, Linda, Dobbs, Jannah, DuBois, Lindreth, Gaultney, Jessica, Gibbs, Deborah, Jordan, Debora, Leef, Donna, Martin, Daniel F., Myles, Robert, Olsen, Timothy, Schwent, Bryan, Srivastava, Sunil, Waldron, Rhonda, Antoszyk, Andrew N., Balasubramaniam, Uma, Brooks, Danielle, Brown, Justin, Browning, David, Clark, Loraine, Ennis, Sarah, Held, Susannah, Helms, Jennifer V., Herby, Jenna, Karow, Angie, Leotaud, Pearl, Massimino, Caterina, McClain, Donna, McOwen, Michael, Mindel, Jennifer, Pereira, Candace, Pierce, Rachel, Powers, Michele, Price, Angela, Rohrer, Jason, Sanders, Jason, Avery, Robert L., Avery, Kelly, Basefsky, Jessica, Beckner, Liz, Castellarin, Alessandro, Couvillion, Stephen, Giust, Jack, Giust, Matthew, Nasir, Maan, Pieramici, Dante, Rabena, Melvin, Risard, Sarah, See, Robert, Smith, Jerry, Wan, Lisha, Bakri, Sophie J., Abu-Yaghi, Nakhleh, Barkmeier, Andrew, Berg, Karin, Burrington, Jean, Edwards, Albert, Goddard, Shannon, Howard, Shannon, Iezzi, Raymond, Lewison, Denise, Link, Thomas, McCannel, Colin A., Overend, Joan, Pach, John, Ruszczyk, Margaret, Shultz, Ryan, Stephan, Cindy, Vogen, Diane, Bradford, Reagan H., Jr., Bergman, Vanessa, Burris, Russ, Butt, Amanda, Daniels, Beth, Dwiggins, Connie, Fransen, Stephen, Guerrero, Tiffany, Haivala, Darin, Harris, Amy, Icks, Sonny, Kingsley, Ronald, Redden, Lena, Richmond, Rob, Ross, Brittany, White, Kammerin, Youngberg, Misty, Topping, Trexler M., Bennett, Steve, Chong, Sandy, Ciotti, Mary, Cleary, Tina, Corey, Emily, Donovan, Dennis, Frederick, Albert, Freese, Lesley, Graham, Margaret, Gud, Natalya, Howard, Taneika, Jones, Mike, Morley, Michael, Moses, Katie, Stone, Jen, Ty, Robin, Wiegand, Torsten, Williams, Lindsey, Winder, Beth, Awh, Carl C., Amonette, Michelle, Arrindell, Everton, Beck, Dena, Busbee, Brandon, Dilback, Amy, Downs, Sara, Guidry, Allison, Gutow, Gary, Hardin, Jackey, Hines, Sarah, Hutchins, Emily, LaCivita, Kim, Lester, Ashley, Malott, Larry, McCain, MaryAnn, Miracle, Jayme, Moffat, Kenneth, Palazzotta, Lacy, Robinson, Kelly, Sonkin, Peter, Travis, Alecia, Wallace, Roy Trent, Winters, Kelly J., Wray, Julia, Harris, April E., Bunnell, Mari, Crooks, Katrina, Fitzgerald, Rebecca, Javid, Cameron, Kew, Corin, Kill, Erica, Kline, Patricia, Kreienkamp, Janet, Martinez, Maricruz, Moore, Roy Ann, Saavedra, Egbert, Taylor, LuAnne, Walsh, Mark, Wilson, Larry, Ciulla, Thomas A., Coyle, Ellen, Harrington, Tonya, Harris, Charlotte, Hood, Cindi, Kerr, Ingrid, Maturi, Raj, Moore, Dawn, Morrow, Stephanie, Savage, Jennifer, Sink, Bethany, Steele, Tom, Thukral, Neelam, Wilburn, Janet, Walker, Joseph P., Banks, Jennifer, Ciampaglia, Debbie, Dyshanowitz, Danielle, Frederick, Jennifer, Ghuman, A. Tom, Grodin, Richard, Kiesel, Cheryl, Knips, Eileen, McCue, Jonathan, Ortiz, Maria, Peters, Crystal, Raskauskas, Paul, Schoeman, Etienne, Sharma, Ashish, Wing, Glenn, Youngblood, Rebecca, Chandra, Suresh R., Altaweel, Michael, Blodi, Barbara, Burke, Kathryn, Dietzman, Kristine A., Gottlieb, Justin, Knutson, Gene, Krolnik, Denise, Nork, T. Michael, Olson, Shelly, Peterson, John, Reed, Sandra, Soderling, Barbara, Somers, Guy, Stevens, Thomas, Wealti, Angela, Bearelly, Srilaxmi, Branchaud, Brenda, Bryant, Joyce W., Crowell, Sara, Fekrat, Sharon, Gammage, Merritt, Harrison, Cheala, Jones, Sarah, McClain, Noreen, McCuen, Brooks, Mruthyunjaya, Prithvi, Queen, Jeanne, Sarin, Neeru, Skalak, Cindy, Skelly, Marriner, Suner, Ivan, Tomany, Ronnie, Welch, Lauren, Park, Susanna S., Cassidy, Allison, Chandra, Karishma, Good, Idalew, Imson, Katrina, Sashi, Kaur, Metzler, Helen, Morse, Lawrence, Redenbo, Ellen, Salvador, Marisa, Telander, David, Thomas, Mark, Wallace, Cindy, Barr, Charles C., Battcher, Amanda, Bottorff, Michelle, Chasteen, Mary, Clark, Kelly, Denning, Diane, Schoen, Debra, Schultz, Amy, Tempel, Evie, Wheeler, Lisa, Whittington, Greg K., Stone, Thomas W., Blevins, Todd, Buck, Michelle, Cruz, Lynn, Heath, Wanda, Holcomb, Diana, Isernhagen, Rick, Kidd, Terri, Kitchens, John, Sears, Cathy, Slade, Ed, Van Arsdall, Jeanne, VanHoose, Brenda, Wolfe, Jenny, Wood, William, Zilis, John, Crooks, Carol, Disney, Larry, Liu, Mimi, Petty, Stephen, Sall, Sandra, Folk, James C., Aly, Tracy, Brotherton, Abby, Critser, Douglas, Hinz, Connie J., Karakas, Stefani, Kirschner, Valerie, Lester, Cheyanne, Montague, Cindy, Russell, Stephen, Stockman, Heather, Taylor, Barbara, Verdick, Randy, Walshire, Jean, Thompson, John T., Connell, Barbara, Constantine, Maryanth, Davis, John L., Jr., Gwen Holsapple, Hunter, Lisa, Lenane, C. Nicki, Mitchell, Robin, Russel, Leslie, Sjaarda, Raymond, Brown, David M., Benz, Matthew, Burns, Llewellyn, Carranza, JoLene G., Fish, Richard, Goates, Debra, Hay, Shayla, Jeffers, Theresa, Kegley, Eric, Kubecka, Dallas, McGilvra, Stacy, Richter, Beau, Sneed, Veronica, Stoever, Cary, Tellez, Isabell, Wong, Tien, Kim, Ivana, Andreoli, Christopher, Barresi, Leslie, Brett, Sarah, Callahan, Charlene, Capaccioli, Karen, Carli, William, Coppola, Matthew, Emmanuel, Nicholas, Evans, Claudia, Fagan, Anna, Grillo, Marcia, Head, John, Kieser, Troy, Lee, Elaine, Lord, Ursula, Miretsky, Edward, Palitsch, Kate, Petrin, Todd, Reader, Liz, Reznichenko, Svetlana, Robertson, Mary, Smith, Justin, Vavvas, Demetrios, Wells, John, Cahill, Cassie, Clark, W. Lloyd, Henry, Kayla, Johnson, David, Miller, Peggy, Oliver, LaDetrick, Spivey, Robbin, Swinford, Tiffany, Taylor, Mallie, Lambert, Michael, Chase, Kris, Fredrickson, Debbie, Khawly, Joseph, Lazarte, Valerie, Lowd, Donald, Miller, Pam, Willis, Arthur, Ferrone, Philip J., Almonte, Miguel, Arnott, Rachel, Aviles, Ingrid, Carbon, Sheri, Chitjian, Michael, DAmore, Kristen, Elliott, Christin, Fastenberg, David, Golub, Barry, Graham, Kenneth, Lavorna, AnnMarie, Murphy, Laura, Palomo, Amanda, Puglisi, Christina, Rhee, David, Romero, Juan, Rosenblatt, Brett, Salcedo, Glenda, Schlameuss, Marianne, Shakin, Eric, Sookhai, Vasanti, Kaiser, Richard, Affel, Elizabeth, Brown, Gary, Centinaro, Christina, Fine, Deborah, Fineman, Mitchell, Formoso, Michele, Garg, Sunir, Grande, Lisa, Herbert, Carolyn, Ho, Allen, Hsu, Jason, Jay, Maryann, Lavetsky, Lisa, Liebenbaum, Elaine, Maguire, Joseph, Monsonego, Julia, O’Connor, Lucia, Pierce, Lisa, Regillo, Carl, Rosario, Maria, Spirn, Marc, Vander, James, Walsh, Jennifer, Davidorf, Frederick H., Barnett, Amanda, Chang, Susie, Christoforidis, John, Elliott, Joy, Justice, Heather, Letson, Alan, McKinney, Kathryne, Perry, Jeri, Salerno, Jill A., Savage, Scott, Shelley, Stephen, Singerman, Lawrence J., Coney, Joseph, DuBois, John, DuBois, Kimberly, Greanoff, Gregg, Himmelman, Dianne, Ilc, Mary, McNamara, Elizabeth, Novak, Michael, Pendergast, Scott, Rath, Susan, Smith-Brewer, Sheila, Tanner, Vivian, Weiss, Diane E., Zegarra, Hernando, Halperin, Lawrence, Aramayo, Patricia, Dhalla, Mandeep, Fernandez, Brian, Fernandez, Cindy, Lopez, Jaclyn, Lopez, Monica, Mariano, Jamie, Murphy, Kellie, Sherley, Clifford, Veksler, Rita, Rahhal, Firas, Babikian, Razmig, Boyer, David, Hami, Sepideh, Kessinger, Jeff, Kurokouchi, Janet, Mukarram, Saba, Pachman, Sarah, Protacio, Eric, Sierra, Julio, Tabandeh, Homayoun, Zamboni, Adam, Elman, Michael, Belz, Jennifer, Butcher, Tammy, Cain, Theresa, Coffey, Teresa, Firestone, Dena, Gore, Nancy, Singletary, Pamela, Sotirakos, Peter, Starr, JoAnn, Meredith, Travis A., Barnhart, Cassandra J., Cantrell, Debra, Esquejo-Leon, RonaLyn, Houghton, Odette, Kaur, Harpreet, NDure, Fatoumatta, Glatzer, Ronald, Joffe, Leonard, Schindler, Reid, Xue, Katie, Hua, Peiying, Maguire, Maureen G., Daniel, Ebenezer, Jaffe, Glenn J., Grunwald, Juan E., and Ying, Gui-shuang

Published
2023
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5. Home OCT Imaging for Newly Diagnosed Neovascular Age-Related Macular Degeneration

Author

Blinder, Kevin J., primary, Calhoun, Claire, additional, Maguire, Maureen G., additional, Glassman, Adam R., additional, Mein, Calvin E., additional, Baskin, Darrell E., additional, Vieyra, Gabriela, additional, Jampol, Lee M., additional, Chica, Moises A., additional, Sun, Jennifer K., additional, Martin, Daniel F., additional, Beck, Roy W., additional, Baptista, Alyssa, additional, Beaulieu, Wesley T., additional, Calhoun, Claire T., additional, Constantine, Sharon R., additional, Dale, Brian B., additional, Dupre, Simone S., additional, Franklin, Crystal A., additional, Galusic, Sandra, additional, Huggins, Meagan, additional, Hunter, Brenda L., additional, Johnson, Paula A., additional, Josic, Kristin, additional, Kelly, Brittany, additional, Liu, Danni, additional, Meadows, Britney, additional, Melia, Michele, additional, Preston, Carin M., additional, Stockdale, Cynthia R., additional, Zokruah, Alice, additional, Bhargava, Sangeeta, additional, Barkmeier, Andrew J., additional, Baskin, Darrell, additional, Blodi, Barbra, additional, Chew, Emily, additional, Ferris, Frederick L., additional, Jaffe, Glenn J., additional, Jhaveri, Chirag D., additional, MacCumber, Mathew, additional, Maturi, Raj K., additional, Solomon, Sharon D., additional, Antoszyk, Andrew N., additional, Lujan, Brandon, additional, Slahi-Had, Hani, additional, Lane, Richard Gary, additional, Adams, Lydia, additional, Rivera, Rachel R., additional, Nakoski, Brenda, additional, Weeks, Rhonda F., additional, Braverman, Allan L., additional, McDonald-Mueller, Lauren, additional, Stuart, Maria A., additional, Pulliam, Brook G., additional, Boyd, Lynda K., additional, Wehmeier, Jarrod, additional, Schremp, Steve A., additional, Googe, Joseph M., additional, Oliver, Kristina, additional, Walsh, Justin, additional, Asher, Julie, additional, Milstead, Katie, additional, Wheeler, Jeff, additional, and Griffone, Hodge A., additional

Published
2023
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6. Changes in activity impairment and work productivity after treatment for vitreous hemorrhage due to proliferative diabetic retinopathy: Secondary outcomes from a randomized controlled trial (DRCR Retina Network Protocol AB).

Author

Beaulieu, Wesley T., Maguire, Maureen G., and Antoszyk, Andrew N.

Subjects
LABOR productivity, VITREOUS body, DIABETIC retinopathy, COMPUTER network protocols, RANDOMIZED controlled trials, RETINA
Abstract

Background: Vitreous hemorrhage from proliferative diabetic retinopathy can cause severe vision loss. DRCR Retina Network Protocol AB was a randomized clinical trial comparing intravitreal aflibercept versus vitrectomy with panretinal photocoagulation and found no difference in the average rate of visual recovery over 104 weeks. Herein, we describe patient-reported outcome measures from Protocol AB. Methods: Secondary analysis of a multicenter (39 sites) randomized clinical trial. The Work Productivity and Activity Impairment Questionnaire was administered at 4, 12, 24, 36, 52, 68, 84, and 104 weeks. Main outcomes were mean change in activity impairment and work productivity loss over 24 and 104 weeks (area under the curve). Results: Mean (SD) activity impairment at baseline was 58% (27%) in the aflibercept group (N = 99) and 56% (30%) in the vitrectomy group (N = 105). The mean reduction in activity impairment from baseline over 24 weeks was 21% (25%) in the aflibercept group and 27% (31%) in the vitrectomy group (adjusted difference = -6.8% [95% CI, -12.7% to -0.9%], P =.02); over 104 weeks, the adjusted mean difference was -3.1% (95% CI, -9.2% to 3.0%, P =.31). Mean work productivity loss at baseline was 51% (28%) in the aflibercept group (N = 44) and 58% (30%) in the vitrectomy group (N = 43). The mean reduction in work productivity loss from baseline over 24 weeks (area under the curve) was 19% (23%) in the aflibercept group and 31% (24%) in the vitrectomy group (adjusted difference = -8.3% [95% CI, -16.8% to 0.2%], P =.06); over 104 weeks, the adjusted mean difference was -9.1% (95% CI, -18.4% to 0.2%, P =.05). Conclusions: Participants with vitreous hemorrhage from proliferative diabetic retinopathy had less activity impairment over 24 weeks when treated initially with vitrectomy and panretinal photocoagulation versus intravitreal aflibercept. The trend was similar for work productivity but not statistically significant. By 104 weeks, the improvements were similar in the two treatment groups. Trial registration: ClinicalTrials.gov NCT02858076. [ABSTRACT FROM AUTHOR]

Published
2023
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7. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials

Author

Heier, Jeffrey S, Lad, Eleonora M, Holz, Frank G, Rosenfeld, Philip J, Guymer, Robyn H, Boyer, David, Grossi, Federico, Baumal, Caroline R, Korobelnik, Jean-Francois, Slakter, Jason S, Waheed, Nadia K, Metlapally, Ravi, Pearce, Ian, Steinle, Nathan, Francone, Anibal A, Hu, Allen, Lally, David R, Deschatelets, Pascal, Francois, Cedric, Bliss, Caleb, Staurenghi, Giovanni, Monés, Jordi, Singh, Rishi P, Ribeiro, Ramiro, Wykoff, Charles C, Cole, Abosede O, Gerstenblith, Adam T, Kotagiri, Ajay, Edwards, Albert O, Zambrano, Alberto D, Eaton, Alexander M, Rubowitz, Alexander, Lyon, Alice T, Chiang, Allen, Ho, Allen, Hu, Allen Y, Guerami, Amir H, Dessouki, Amr L, de Carvalho, André Corrêa Maia, Emanuelli, Andrés, Chang, Andrew A, Antoszyk, Andrew N, Francone, Anibal Andrés, Prasad, Anita, Wolf, Armin, Khanani, Arshad M, Abbey, Ashkan Michael, Moulana, Asma, Wihelm, Barbara, Sikorski, Bartosz L, Kuppermann, Baruch D, Wolff, Benjamin, Jewart, Brian H, Do, Brian K, Chan-Kai, Brian T, Mein, Calvin, Hoyng, Carel B, Awh, Carl C, Regillio, Carl, Zeolite, Carlos, Baumal, Caroline R, Creuzot-Garcher, Catherine, Maury, Catherine Français, Wykoff, Charles C, Newell, Charles K, Jhaveri, Chirag, Lohmann, Chris P, Dinah, Christiana B, Ma, Colin, Crawford, Courtney, Parke, D Wilkin, Lavinsky, Daniel, Roth, Daniel, Pieramici, Dante J, Moshfeghi, Darius M, Levin, Darrin, Saperstein, David A, Brown, David, Gaucher, David, Lally, David R, Liao, David S, Brown, David Warren, Goldstein, Debra, Marcus, Dennis, Chan, Derek G, Dhoot, Dilsher, Tacite, Domingo, Zalewski, Dominik, Espana, Edgar M, Lad, Eleonora M, Souied, Eric H, Suan, Eric P, Eting, Eva, Sola, Federico Furno, de Bats, Flore, Bandello, Francesco, Gómez-Ulla, Francisco, Devin, François, Holz, Frank G, Chen, Fred K, Makkouk, Fuad, Dyer, Gawain, Spital, George, Staurenghi, Giovanni, Stoller, Glenn, Cousins, Gwen, Salehi-Had, Hani, Agostini, Hansjürgen, Eleftheriadis, Haralabos, Weiss, Harold, Sultan, Harris C, Massé, Hélène, Pearce, Ian, Dias, Indra, Barbazetto, Irene, Rosenblatt, Irit, Suñer, Ivan J, Kovach, Jaclyn L, Kaluzny, Jakub, Borthwick, James, Howard, James G, Wong, James, Ernest, Jan, Němčanský, Jan, Ysasaga, Jason Edward, Handza, Jason M, Moreno, Javier Antonio Montero, Korobelnik, Jean-François, Heier, Jeffrey S, Arnold, Jennifer J, Brown, Jeremiah, Bafalluy, Joaquin, Pearlman, Joel, Pitcher, John D, Kitchens, John, Carlson, John P, Gilhotra, Jolly, Fein, Jordana, Monés, Jordi M, Luna, José Domingo, Moreno, José María Ruiz, Coney, Joseph M, Sallum, Juliana Maria Ferraz, Olsen, Karl R, Blobner, Katharina, Macoul, Katherine A, Oh, Kean T, Malik, Khurram Javed, Hattenbach, Lars-Olof, Kodjikian, Laurent, Neto, Laurentino Biccas, Singerman, Lawrence J, Altay, Lebriz, Sheck, Leo-H, Feiner, Leonard, Harris, Lindsey D, Chishold, Lionel D, Rao, Llewelyn J, Nehemy, Márcio Bittar, Elizalde, Maria Jose Capella, Gamulescu, Maria-Andreea, Saravia, Mario J, Johnson, Mark W, McKibbin, Martin, Maccumber, Mathew, Vidosevich, Matko, Ohr, Matthew P, Samuel, Michael A, Singer, Michael A, Cassell, Michael, Dollin, Michael, Elman, Michael J, Ip, Michael S, Goldstein, Michaella, Busquets, Miguel, Mititelu, Mihai, Shah, Milan, Veith, Miroslav, Fineman, Mitchell, Varano, Monica, Christmas, Nancy, Steinle, Nathan C, Chaudhry, Nauman, Chinskey, Nicholas D, Eter, Nicole, London, Nikolas J S, Mathalone, Nurit, Schlottmann, Patricio G, Coady, Patrick, Higgins, Patrick M, Raskauskas, Paul A, Yates, Paul A, Bernstein, Paul, Mitchell, Paul, Monsour, Paul, Raphaelian, Paul V, Stanga, Paulo E, Stodulka, Pavel, Issa, Peter Charbel, Pavan, Peter, Ferrone, Phil J, Oleksy, Piotr, Abraham, Prema, Mruthyunjaya, Prithvi, Nguyen, Quan Dong, Reddy, Rahul K, Khurana, Rahul N, Tuli, Raman, Tadayoni, Ramin, Katz, Randy Steven, Arora, Rashi, Schlingemann, Reinier O, Rosen, Richard B, Gale, Richard, Scartozzi, Richard, Isernharge, Ricky, Singh, Rishi P, Stoltz, Robert A, Avery, Robert L, Wirthlin, Robert S, Guymer, Robyn, Goldberg, Roger A, Frenkel, Ronald, Belfort, Rubens Jr, Mohand-Said, Saddek, Grisanti, Salvatore, Razavi, Sam, Fraser-Bell, Samantha, Shah, Sandeep N, Wickremasinghe, Sanjeewa, Haug, Sara Joy, Adrean, Sean D, Priglinger, Siegfried G, Esposti, Simona Degli, Guest, Stephen, Huddleston, Stephen, Itty, Sujit, Moon, Suk Jin, Bhatia, Sumit P, Gupta, Sunil, Patel, Sunil S, Garg, Sunir J, Joshi, Sunir, Nghiem-Buffet, Sylvia, Johnson, T Mark, Jaouni, Tareq, Ach, Thomas, Williams, Thomas R, Sheidow, Thomas, Cleland, Timothy P, You, Timothy T, Peto, Tunde, Konidaris, Vasileios, Gonzalez, Victor H, Korda, Vladimir, Freeman, William R, Bridges, William Z, Barak, Yoreh, Zagorski, Zbigniew, Yehoshua, Zohar, and Dubska, Zora

Abstract

Geographic atrophy is a leading cause of progressive, irreversible vision loss. The objectives of OAKS and DERBY were to assess the efficacy and safety of pegcetacoplan compared with sham treatment in patients with geographic atrophy.

Published
2023
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9. Association of Baseline Visual Acuity and Retinal Thickness With 1-Year Efficacy of Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema

Author

Wells, John A., Glassman, Adam R., Jampol, Lee M., Aiello, Lloyd Paul, Antoszyk, Andrew N., Baker, Carl W., Bressler, Neil M., Browning, David J., Connor, Crystal G., Elman, Michael J., Ferris, Frederick L., Friedman, Scott M., Melia, Michele, Pieramici, Dante J., Sun, Jennifer K., and Beck, Roy W.

Published
2016
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10. Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial

Author

Gross, Jeffrey G., Glassman, Adam R., Jampol, Lee M., Inusah, Seidu, Aiello, Lloyd Paul, Antoszyk, Andrew N., Baker, Carl W., Berger, Brian B., Bressler, Neil M., Browning, David, Elman, Michael J., Ferris, Frederick L., III, Friedman, Scott M., Marcus, Dennis M., Melia, Michele, Stockdale, Cynthia R., Sun, Jennifer K., and Beck, Roy W.

Published
2015
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16. Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression: AREDS2 Report No. 3

Author

Chew, Emily Y., Clemons, Traci E., SanGiovanni, John Paul, Danis, Ronald P., Ferris, Frederick L., III, Elman, Michael J., Antoszyk, Andrew N., Ruby, Alan J., Orth, David, Bressler, Susan B., Fish, Gary E., Hubbard, George Baker, Klein, Michael L., Chandra, Suresh R., Blodi, Barbara A., Domalpally, Amitha, Friberg, Thomas, Wong, Wai T., Rosenfeld, Philip J., Agrón, Elvira, Toth, Cynthia A., Bernstein, Paul S., and Sperduto, Robert D.

Published
2014
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18. Lutein/Zeaxanthin for the Treatment of Age-Related Cataract: AREDS2 Randomized Trial Report No. 4

Author

Chew, Emily Y., SanGiovanni, John Paul, Ferris, Frederick L., III, Wong, Wai T., Agron, Elvira, Clemons, Traci E., Sperduto, Robert, Danis, Ronald, Chandra, Suresh R., Blodi, Barbara A., Domalpally, Amitha, Elman, Michael J., Antoszyk, Andrew N., Ruby, Alan J., Orth, David, Bressler, Susan B., Fish, Gary E., Hubbard, George B., Klein, Michael L., Friberg, Thomas R., Rosenfeld, Philip J., Toth, Cynthia A., and Bernstein, Paul

Published
2013
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24. Effect of Intravitreous Anti-Vascular Endothelial Growth Factor vs Sham Treatment for Prevention of Vision-Threatening Complications of Diabetic Retinopathy: The Protocol W Randomized Clinical Trial.

Author

Maturi, Raj K, Glassman, Adam R, Josic, Kristin, Antoszyk, Andrew N, Blodi, Barbara A, Jampol, Lee M, Marcus, Dennis M, Martin, Daniel F, Melia, Michele, Salehi-Had, Hani, Stockdale, Cynthia R, Punjabi, Omar S, Sun, Jennifer K, and DRCR Retina Network

Published
2021
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27. Effect of Intravitreous Aflibercept vs Vitrectomy With Panretinal Photocoagulation on Visual Acuity in Patients With Vitreous Hemorrhage From Proliferative Diabetic Retinopathy: A Randomized Clinical Trial.

Author

Antoszyk, Andrew N., Glassman, Adam R., Beaulieu, Wesley T., Jampol, Lee M., Jhaveri, Chirag D., Punjabi, Omar S., Salehi-Had, Hani, Wells III, John A., Maguire, Maureen G., Stockdale, Cynthia R., Martin, Daniel F., Sun, Jennifer K., Wells, John A 3rd, and DRCR Retina Network

Subjects
*VITRECTOMY, *LIGHT coagulation, *DIABETIC retinopathy, *VISUAL acuity, *RANDOMIZED controlled trials, *VASCULAR endothelial growth factor antagonists, *RETINAL surgery, *RESEARCH, *NEOVASCULARIZATION inhibitors, *CONFIDENCE intervals, *INJECTIONS, *RESEARCH methodology, *EYE hemorrhage, *CELL receptors, *SURGICAL complications, *EVALUATION research, *MEDICAL cooperation, *CATARACT surgery, *TREATMENT effectiveness, *COMPARATIVE studies, *RESEARCH funding, *RECOMBINANT proteins, *DISEASE complications
Abstract

Importance: Vitreous hemorrhage from proliferative diabetic retinopathy can cause loss of vision. The best management approach is unknown.Objective: To compare initial treatment with intravitreous aflibercept vs vitrectomy with panretinal photocoagulation for vitreous hemorrhage from proliferative diabetic retinopathy.Design, Setting, and Participants: Randomized clinical trial at 39 DRCR Retina Network sites in the US and Canada including 205 adults with vison loss due to vitreous hemorrhage from proliferative diabetic retinopathy who were enrolled from November 2016 to December 2017. The final follow-up visit was completed in January 2020.Interventions: Random assignment of eyes (1 per participant) to aflibercept (100 participants) or vitrectomy with panretinal photocoagulation (105 participants). Participants whose eyes were assigned to aflibercept initially received 4 monthly injections. Both groups could receive aflibercept or vitrectomy during follow-up based on protocol criteria.Main Outcomes and Measures: The primary outcome was mean visual acuity letter score (range, 0-100; higher scores indicate better vision) over 24 weeks (area under the curve); the study was powered to detect a difference of 8 letters. Secondary outcomes included mean visual acuity at 4 weeks and 2 years.Results: Among 205 participants (205 eyes) who were randomized (mean [SD] age, 57 [11] years; 115 [56%] men; mean visual acuity letter score, 34.5 [Snellen equivalent, 20/200]), 95% (195 of 205) completed the 24-week visit and 90% (177 of 196, excluding 9 deaths) completed the 2-year visit. The mean visual acuity letter score over 24 weeks was 59.3 (Snellen equivalent, 20/63) (95% CI, 54.9 to 63.7) in the aflibercept group vs 63.0 (Snellen equivalent, 20/63) (95% CI, 58.6 to 67.3) in the vitrectomy group (adjusted difference, -5.0 [95% CI, -10.2 to 0.3], P = .06). Among 23 secondary outcomes, 15 showed no significant difference. The mean visual acuity letter score was 52.6 (Snellen equivalent, 20/100) in the aflibercept group vs 62.3 (Snellen equivalent, 20/63) in the vitrectomy group at 4 weeks (adjusted difference, -11.2 [95% CI, -18.5 to -3.9], P = .003) and 73.7 (Snellen equivalent, 20/40) vs 71.0 (Snellen equivalent, 20/40) at 2 years (adjusted difference, 2.7 [95% CI, -3.1 to 8.4], P = .36). Over 2 years, 33 eyes (33%) assigned to aflibercept received vitrectomy and 34 eyes (32%) assigned to vitrectomy received subsequent aflibercept.Conclusions and Relevance: Among participants whose eyes had vitreous hemorrhage from proliferative diabetic retinopathy, there was no statistically significant difference in the primary outcome of mean visual acuity letter score over 24 weeks following initial treatment with intravitreous aflibercept vs vitrectomy with panretinal photocoagulation. However, the study may have been underpowered, considering the range of the 95% CI, to detect a clinically important benefit in favor of initial vitrectomy with panretinal photocoagulation.Trial Registration: ClinicalTrials.gov Identifier: NCT02858076. [ABSTRACT FROM AUTHOR]

Published
2020
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28. Home OCT Imaging for Newly Diagnosed Neovascular Age-Related Macular Degeneration

Author

Blinder, Kevin J., Calhoun, Claire, Maguire, Maureen G., Glassman, Adam R., Mein, Calvin E., Baskin, Darrell E., Vieyra, Gabriela, Jampol, Lee M., Chica, Moises A., Sun, Jennifer K., Martin, Daniel F., Glassman, Adam R., Beck, Roy W., Baptista, Alyssa, Beaulieu, Wesley T., Calhoun, Claire T., Constantine, Sharon R., Dale, Brian B., Dupre, Simone S., Franklin, Crystal A., Galusic, Sandra, Huggins, Meagan, Hunter, Brenda L., Johnson, Paula A., Josic, Kristin, Kelly, Brittany, Liu, Danni, Maguire, Maureen G., Meadows, Britney, Melia, Michele, Preston, Carin M., Stockdale, Cynthia R., Zokruah, Alice, Sun, Jennifer K., Martin, Daniel F., Bhargava, Sangeeta, Barkmeier, Andrew J., Baskin, Darrell, Beck, Roy W., Blodi, Barbra, Chew, Emily, Ferris, Frederick L., Jaffe, Glenn J., Jampol, Lee M., Jhaveri, Chirag D., MacCumber, Mathew, Martin, Daniel F., Maturi, Raj K., Solomon, Sharon D., Stockdale, Cynthia R., Antoszyk, Andrew N., Lujan, Brandon, Jhaveri, Chirag D., Chew, Emily, Maturi, Raj K., Ferris, Frederick L., Jampol, Lee M., Martin, Daniel F., Slahi-Had, Hani, Stockdale, Cynthia R., Barkmeier, Andrew J., Lane, Richard Gary, Adams, Lydia, Rivera, Rachel R., Nakoski, Brenda, Weeks, Rhonda F., Braverman, Allan L., McDonald-Mueller, Lauren, Stuart, Maria A., Pulliam, Brook G., Boyd, Lynda K., Wehmeier, Jarrod, Schremp, Steve A., Googe, Joseph M., Oliver, Kristina, Walsh, Justin, Asher, Julie, Milstead, Katie, Wheeler, Jeff, and Griffone, Hodge A.

Abstract

To assess the feasibility of daily Home OCT imaging among patients with neovascular age-related macular degeneration (nAMD).

Published
2024
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29. Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti–Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema

Author

Jampol, Lee M., primary, Glassman, Adam R., additional, Liu, Danni, additional, Aiello, Lloyd Paul, additional, Bressler, Neil M., additional, Duh, Elia J., additional, Quaggin, Susan, additional, Wells, John A., additional, Wykoff, Charles C., additional, Browning, David, additional, Antoszyk, Andrew N., additional, Price, Angela K., additional, Fredenberg, Sherry L., additional, Herby, Jenna T., additional, Fleming, Christina J., additional, McClain, Ashley A., additional, Ennis, Sarah A., additional, Gallagher, Kelly R., additional, Karow, Angella S., additional, Grupp, Autumn C., additional, Puskas, Danielle, additional, Watson, Lynn, additional, Bojaj, Swann J., additional, Balasubramaniam, Uma M., additional, McClain, Donna, additional, Styles, Donna R., additional, Kuopus, Jeff A., additional, Kimrey, Kathryn, additional, Clark, Loraine M., additional, Jackson, Lisa A., additional, McOwen, Michael D., additional, Dunlap, Matt, additional, Held, Susannah J., additional, Pieramici, Dante J., additional, Nasir, Ma'an A., additional, Castellarin, Alessandro A., additional, Dhoot, Dilsher, additional, Fishbein, Sarah, additional, Giust, Jack, additional, Wan, Lisha, additional, Hanna, Michelle S., additional, Rabena, Melvin D., additional, Smith, Jerry, additional, Bone, Layne J., additional, Avery, Kelly, additional, Giust, Matthew, additional, Walker, Aimee, additional, Shook, Aimee H., additional, Esau, Sara, additional, Ruvalcaba, Nitce L., additional, Clark, W. Lloyd, additional, Johnson, David L., additional, Payne, John F., additional, Swinford, Tiffany R., additional, Taylor, Mallie M., additional, Garrison, Cassandra L., additional, Miller, Peggy D., additional, Houlahan, Amber R., additional, O'Neill, Charlotte A., additional, Floyd, Ashley, additional, Parker, Crystal C., additional, Sease, Courtney, additional, Graham, Tara, additional, Spencer, Robin, additional, Ogbuewu, Tiffany N., additional, Studebaker, Ashley, additional, Huggins, Tyler, additional, Spivey, Robbin, additional, Jones, Brian, additional, Williams, Ashley, additional, Petty, Ron, additional, Poston, Erin L., additional, Ward, G. Michael, additional, Baker, Carl W., additional, Tilford, Ron H., additional, Caldwell, Tracey M., additional, Lambert, Lynnette F., additional, Palmer, Mary J., additional, Martin, Tracey R., additional, Williams, Tana R., additional, Kettler, Samantha, additional, Camp, Alecia B., additional, Silva, Paolo S., additional, Arrigg, Paul G., additional, Sharuk, George S., additional, Shah, Sabera T., additional, Sun, Jennifer K., additional, Westerfeld, Corey, additional, Andreoli, Christopher Michael, additional, Schlossman, Deborah, additional, Murtha, Timothy, additional, Kwak, Hanna, additional, Flores, Flor M., additional, Stockman, Margaret E., additional, Kieser, Troy, additional, Krigman, Michael N., additional, Bestourous, Leila, additional, Weimann, Elizabeth S., additional, Cavallerano, Jerry D., additional, Hock, Kristen M., additional, Robertson, Mary Ann, additional, Kirby, Rita K., additional, Papaconstantinou, Steve L., additional, Madigan, Kylie M., additional, Cavicchi, Robert W., additional, Palitsch, Kate A., additional, Yilmaz, Taygan, additional, Berger, Brian B., additional, Jhaveri, Chirag D., additional, Moore, Tori, additional, Manhart, Ginger J., additional, Walsh, Rachel A., additional, Gunderson, Ivana, additional, Riepen, Dietrich, additional, Bravenec, Chelsey A., additional, Reid, Ryan M., additional, Ren, Yong, additional, Ostrander, Ben, additional, Stovall, Christopher C., additional, Elman, Michael J., additional, Liss, Robert A., additional, Leder, Henry A., additional, Starr, JoAnn, additional, Belz, Jennifer L., additional, Putzulo, Charlene K., additional, Sandler, Dallas R., additional, Simmons, Jennifer L., additional, Singletary, Pamela V., additional, Davis, Ashley, additional, Simpson, Perel M., additional, Coffey, Teresa, additional, Ketner, Daniel J., additional, Cain, Terri, additional, Metzger, Ashley M., additional, Sotirakos, Peter, additional, Marcus, Dennis M., additional, Singh, Harinderjit, additional, Roberts, Courtney N., additional, Floyd, Geri L., additional, Ortiz, Siobhan O., additional, Mims, Virginia, additional, Foster, L. Allison, additional, Coursey, Christy, additional, Gardner, Jared C., additional, Ivey, Ken, additional, O'Keefe, John Stewart, additional, Astruc, Juan A., additional, Schwent, Bryan J., additional, Tabassian, Ali R., additional, Rosen, Suzette A., additional, Vaughan, David C., additional, Michaels, Jeffrey, additional, Arndt, Natalie J., additional, Maziarz, John J., additional, Friedman, Scott M., additional, Moinfar, Nader, additional, Williamson, Kimberly A., additional, Fagan, Damanda F., additional, Dawson, Katrina L., additional, Walters, Paige N., additional, McKinney, Allen, additional, Carlton, Steve, additional, Kwun, Robert C., additional, Knudsen, Victoria L., additional, Winward, Kirk E., additional, Swartz, Mano, additional, Howard, James G., additional, Riley, Michelle, additional, Taylor, Gena, additional, Holt, Michelle, additional, Winward, Jason G., additional, Walsh, Adam, additional, Taylor, Teresa, additional, Walsh, Daniel, additional, Hampton, G. Robert, additional, Brown, Jamin S., additional, Seth, Rajeev K., additional, Sienkiewycz, Laurie J., additional, Appleton, Deborah A., additional, Grinnell, Cindy J., additional, Cowley, Charity A., additional, Kwasniewski, Lynn M., additional, Manley, Michelle L., additional, Robarge, Nicole E., additional, DeSantis, Stefanie R., additional, Hay, Peter B., additional, DeForge, Teresa M., additional, Wong, Tien P., additional, Chen, Eric, additional, Brown, David M., additional, Kim, Rosa Y., additional, Major, James C., additional, Schefler, Amy C., additional, Fish, Richard H., additional, Benz, Matthew S., additional, Lipman, Meredith, additional, Hutson, Amy, additional, Landaverde, Nubia, additional, Chancey, Ashley E., additional, Cone, Cassie, additional, Royse, Tressa, additional, Sneed, Veronica A., additional, Almanza, Belinda A., additional, Dives, Brenda, additional, Richter, Beau A., additional, Kegley, Eric N., additional, Lauer, Andreas K., additional, Flaxel, Christina J., additional, Bailey, Steven T., additional, Schain, Mitchell, additional, Lundquist, Ann D., additional, Hanel, Shelley A., additional, Ira, Shirley D., additional, Nolte, Susan K., additional, Steinkamp, Peter N., additional, Ryan, Dawn M., additional, Pickell, Scott R., additional, Hui, Jocelyn T., additional, Brix, Michelle, additional, Barth, Jordan, additional, Howell, Chris S., additional, Fox, Gregory M., additional, Cooper, Blake A., additional, Batlle, Ivan R., additional, Manning, Lexie R., additional, Batlle, Karla A., additional, Wyrick, Holly, additional, Pippin, Katherine, additional, Perkins, Samantha, additional, Yeager, Frank T., additional, Rush, Ryan B., additional, Gardner, Glenn R., additional, Rush, Christi, additional, Hawkins, Johnathan R., additional, Dumas, Brenda, additional, Ysasaga, Ben, additional, Shah, Chirag P., additional, Morley, Michael G., additional, Wiegand, Torsten W., additional, Cleary, Tina S., additional, Topping, Trexler M., additional, Colegrove, Lindsey, additional, Bechtel, Katharine, additional, Johnson, Britta, additional, Lebedew, Lisa, additional, Lorius, Natacha, additional, Chong, Sandy G., additional, Stone, Jennifer L., additional, Jones, Michael Cullen, additional, Donovan, Dennis, additional, Malone, Sherry, additional, Graham, Margie, additional, Santos, Audrey, additional, Bennett, Steve A., additional, Blinder, Kevin J., additional, Smith, Bradley T., additional, Nobel, Ginny S., additional, Weeks, Rhonda F., additional, Hoehn, Erika A., additional, Stuart, Maria A., additional, Pepple, Kelly E., additional, Boyd, Lynda K., additional, Pulliam, Brook G., additional, Schremp, Steve A., additional, Guevara, Stephanie L., additional, Wehmeier, Jarrod, additional, Wright, Timothy L., additional, Gabel, Dana L., additional, Miller, David G., additional, Schartman, Jerome P., additional, Singerman, Lawrence J., additional, Coney, Joseph M., additional, Novak, Michael A., additional, Rao, Llewelyn J., additional, Rath, Susan C., additional, McNamara, Elizabeth, additional, Stone, Larraine, additional, Smith, Veronica A., additional, Rykena, Cecelia, additional, DuBois, Kimberly A., additional, Ilc, Mary A., additional, Tanner, Vivian, additional, Drury, Kim, additional, Nitzsche, Trina M., additional, Greanoff, Gregg A., additional, DuBois, John C., additional, Burgess, Stuart K., additional, Lara, Tirso M., additional, Pereda, Noel H., additional, Fernandez, Cindy V., additional, Davis, Deborah, additional, Quinchia, Evelyn, additional, Workman, Karen, additional, Nielsen, Jared S., additional, Sohn, Jeong-Hyeon, additional, Alliman, Kyle J., additional, Saggau, David D., additional, Parker, Marianne, additional, George, Bethany, additional, Eastvold, Carrie L., additional, Sells, Kristin, additional, Woehl, Tami Jo, additional, Johnson, Marilyn A., additional, Keenan, Holly, additional, Coleman, Jennifer L., additional, Spillman, Jamie, additional, Freeman, Shannon, additional, Schmidt, Leigh S., additional, Boender, Lisa M., additional, Partin, Jill L., additional, Bennett, Bailey R., additional, Rostvold, Jay, additional, McLure Stone, Cameron, additional, Raymer, Lea R., additional, Menzel, Andrea K., additional, Rickman, Leslie D., additional, Campbell, Barbara, additional, Sherlin, Lorraine P., additional, Hawkins, Lisa H., additional, Buckner, Melissa L., additional, Matsipura, Olesya N., additional, Price, Paula A., additional, Ghuman, A. Thomas, additional, Raskauskas, Paul A., additional, Sharma, Ashish G., additional, Wing, Glenn, additional, Walker, Joseph P., additional, Knips, Eileen, additional, Kiesel, Cheryl, additional, Peters, Crystal Y., additional, Ryan, Cheryl, additional, Greenhoe, Laura, additional, Torres, Natalie N., additional, Youngblood, Rebecca J., additional, Turnbo, Danielle, additional, Leslie, Anita H., additional, Schoeman, Etienne C., additional, Kiesel, Raymond K., additional, Kingsley, Ronald M., additional, Shah, Vinay A., additional, Leonard, Robert E., additional, Miller, Heather R., additional, Icks, Sonny, additional, Bergman, Vanessa A., additional, Drummond, Vanessa K., additional, Ross, Brittany L., additional, Ellis, Reshial D., additional, Whittington, Tina R., additional, Almeida, Shannon R., additional, Butt, Amanda M., additional, Burris, Russ, additional, Peters, Mark A., additional, Lee, Michael S., additional, Tlucek, Paul S., additional, Ma, Colin, additional, Hobbs, Stephen, additional, Milliron, Amanda C., additional, Ho, Stephanie L., additional, Kopfer, Marcia, additional, Logan, Joe, additional, Hoerner, Christine, additional, Khawly, Joseph A., additional, Rahman, Hassan T., additional, Abdelgani, Diana, additional, Miller, Pam S., additional, Fredrickson, Debbie, additional, Pineda, Erica, additional, Lopez, Desiree, additional, Lowd, Donald K., additional, Blank, Colin, additional, Martinez, Lorena R., additional, Muniz, Jason E., additional, Gottlieb, Justin, additional, Ip, Michael S., additional, Blodi, Barbara A., additional, Dietzman, Kristine A., additional, Burke, Kathryn F., additional, Smith, Christopher M., additional, Olson, Shelly R., additional, Wealti, Angela M., additional, Reed, Sandie L., additional, Krolnik, Denise A., additional, Peterson, John C., additional, Gonzalez, Victor Hugo, additional, Diaz-Rohena, Roberto, additional, Santiago, Juan G., additional, Adyanthaya, Rohit, additional, Patel, Nehal R., additional, Anaya, Deyla, additional, Garcia, Dina, additional, Cruz, Edna E., additional, Alvarez, Crystal A., additional, Iracheta, Ruth, additional, Rodriguez, Jessica, additional, Cantu, Monica R., additional, Flores, Rebecca R., additional, Jasso, Hector, additional, Rodriguez, Rachel, additional, Miranda, Karina, additional, Lozano, Krystle R., additional, Garza, Maricela, additional, Aguero, Lazaro, additional, Sandoval, Amanda L., additional, Montemayor, Monique, additional, Alonso, Samuel, additional, Garza, Santos, additional, DiLoreto, David Allen, additional, Ramchandran, Rajeev S., additional, Kleinman, David M., additional, O'Gara, George W., additional, Czubinski, Andrea M., additional, MacDowell, Peter, additional, Steinmetz, Kari M., additional, Castillo, Dan A., additional, Yu, Yvonne F., additional, Tongue, Salina M., additional, Keim, Melissa S., additional, Hollar, Rachel, additional, Deats, Brandi N., additional, Richardson, Brittany S., additional, Singer, Lynn, additional, Pannell, Taylor A., additional, Daniels, Stewart A., additional, Ranchod, Tushar M., additional, Leong, Craig J., additional, Touson, Stacey, additional, Earl, Shannon R., additional, Bartlett, Melissa C., additional, Fernando, Christine, additional, Factor, Djorella, additional, Garcia, Jessica, additional, Nguyen, Anna K., additional, Hom, Betty, additional, Walker, Cathy, additional, Marudo, Grace M., additional, Suazo, Jose Carlos, additional, McNeil, Leah M., additional, Hanamoto, Fred, additional, Hughes, Matthew D., additional, Ross, Robin D., additional, Sanford, Susan M., additional, Markiewicz, Nicole Martini, additional, Utley, Tracy M., additional, Henderson, Shannon, additional, Lippincott, Joanie H., additional, Streasick, Patricia, additional, Glazer, Louis C., additional, Garber, Frank W., additional, Zheutlin, Jeffrey D., additional, Listerman, Angela D., additional, Feehan, Christine E., additional, Cruz, Heather L., additional, Kuitula, Donald E., additional, Rainey, Olivia P., additional, Weatherbee, Sue, additional, Googe, Joseph M., additional, Shuler, R. Keith, additional, Anderson, Nicholas G., additional, Perkins, Stephen L., additional, Oliver, Kristina, additional, Grindall, Nicole, additional, Arnold, Ann, additional, Beerbower, Jennifer, additional, Hunt, Cecile, additional, Schulz, Kathy L., additional, Oelrich, Sarah M., additional, Whetstone, Jerry K., additional, Walsh, Justin, additional, Morris, Chris, additional, Wong, Robert W., additional, Nixon, Peter A., additional, Leon, Jeni L., additional, Montesclaros, Chris A., additional, Leung, Carrie E., additional, Le, Phill, additional, Harborth, Codey L., additional, Rodriguez, Margaret A., additional, Mangham, Cory, additional, Aaberg, Thomas M., additional, Westhouse, Scott J., additional, Vincent, Holly L., additional, Malone, Rebecca, additional, Karsten, Kathy L., additional, Maturi, Raj K., additional, Harless, Ashley M., additional, Novak, Carolee K., additional, Bleau, Laura A., additional, Steele, Thomas, additional, Harris, Charlotte, additional, Bildner, Alisha, additional, Maple, Abby, additional, Stone, Thomas W., additional, Isernhagen, Rick D., additional, Kitchens, John W., additional, Holcomb, Diana M., additional, Van Arsdall, Jeanne, additional, Buck, Michelle, additional, Slade, Edward A., additional, Chiu, Mark T., additional, Reddy, Ashok K., additional, Wyant, Frank W., additional, Montano-Niles, Mary M., additional, Carter, Lorraine J., additional, Maerki, Shirley, additional, Tartaglia, Laura, additional, Gomez, Paul P., additional, Maestas, Stephen A., additional, Shanta, Camille, additional, Jimenez, Lisbrenda M., additional, Stoltz, Robert A., additional, Vanderveldt, Stephanie L., additional, Lampert, Scott I., additional, Marcus, Leslie G., additional, Fulbright, Shelly, additional, Martin, James P., additional, Novack, Roger L., additional, Liao, David S., additional, Lo, Tammy Eileen, additional, Kurokouchi, Janet, additional, Ngo, Richard, additional, Hoang, Connie V., additional, Sierra, Julio, additional, Zamboni, Adam, additional, Protacio, Eric G., additional, Kessinger, Jeff, additional, Garg, Seema, additional, Houghton, Odette M., additional, Ulrich, Jan Niklas, additional, Chavala, Sai H., additional, DuBose, Elizabeth L., additional, Barnhart, Cassandra J., additional, Karmalkar, Megha, additional, Jani, Pooja D., additional, Goble, Justin, additional, Cantrell, Debra, additional, Esquejo, Rona Lyn, additional, Shah, Sandeep N., additional, Harmon, Natasha, additional, Dhalla, Mandeep S., additional, del Cid, Mario R., additional, Halperin, Lawrence S., additional, Brady, Jaclyn A., additional, Hamlin, Monica, additional, Lopez, Monica L., additional, Mariano, Jamie, additional, Neale, Candace M., additional, Veksler, Rita R., additional, Mannarelli, Angelica, additional, Coffee, Robert E., additional, Carvounis, Petros Euthymiou, additional, Hemati, Pejman, additional, Dorenbach, Cindy J., additional, Joshi, Annika S., additional, Leger, April, additional, Barnett, Dana B., additional, Morales, Joseph F., additional, Mansour, Sam E., additional, Choyce, Cathy, additional, Dirawatun, Aissa L., additional, Nagy, Emma A., additional, Kerkstra, Jamie C., additional, Fan, Joseph T., additional, Suthar, Mukesh Bhogilal, additional, Rauser, Michael E., additional, Santiago, Gisela, additional, Marvyn Cerdenio, Liel, additional, Perez, Brandi J., additional, Halsey, Kara E., additional, Kiernan, William H., additional, Knabb, Jesse, additional, Catren, Rachel, additional, Shami, Michel, additional, Arrington, Brenda K., additional, Neuling, Keri S., additional, Meeks, Ashaki, additional, Garcia, Natalie R., additional, Blair, Kayla, additional, Rhymes, Ginger K., additional, Medrano, Janet, additional, Kim, Judy E., additional, Weinberg, David V., additional, Stepien, Kimberly E., additional, Connor, Thomas B., additional, Williams, Vesper V., additional, Kaczanowski, Tracy L., additional, Packard, Krissa L., additional, Flanders, Judy, additional, Barwick, Vicki, additional, Winter, Pat A., additional, Beringer, Joseph R., additional, Selchert, Kathy J., additional, Lehr, John T., additional, Rodriguez-Roman, Elaine, additional, Jones, Teri, additional, Haddox, Martha Eileen, additional, Pena, Mark, additional, Hernandez, Brenda, additional, Chan, Clement K., additional, Lalezary, Maziar, additional, Lin, Steven G., additional, Walther, Kimberly S., additional, Gonzales, Tiana, additional, Myers, Lenise E., additional, Huff, Kenneth M., additional, Chace, Richard, additional, Kallay, Sunny, additional, Stevens, Kirsten, additional, Dolbec, Nicole, additional, Baker-Hill, Ronda, additional, Surette, Janea, additional, Rose, Steven J., additional, Connolly, Brian P., additional, Guillet, Ernest G., additional, Hall, Edward F., additional, Yagoda, Margaret M., additional, Doran, Mary Jo, additional, Burgess, Mindy, additional, Reynard, Ann, additional, Powers, Margaret, additional, Territo, Joe, additional, Mein, Calvin E., additional, Chica, Moises A., additional, Lane, R. Gary, additional, Holy, Sarah Elizabeth, additional, Kirschbaum, Lita, additional, Martinez, Vanessa D., additional, Baker, Jaynee, additional, Kincaid, Christa G., additional, Castillo, Elaine, additional, Wienecke, Christopher Sean, additional, Schlichting, Sara L., additional, Nakoski, Brenda, additional, Diddie, Kenneth R., additional, Cadwell, Deborah M., additional, Van Arsdale, Louise, additional, Boisvert, Taryn F., additional, Galonsky, Joyce, additional, O'Hayer, Susie, additional, Johnson, Melissa L., additional, McCabe, Frank J., additional, Baker, Brad J., additional, Defrin, Melvyn H., additional, Lampson, Marie V., additional, Pratte, Heather, additional, Baron, Selena A., additional, Borelli, Aundrea S., additional, Davidorf, Frederick H., additional, Wells, Michael B., additional, Chang, Susie, additional, Christoforidis, John Byron, additional, Letson, Alan D., additional, Salerno, Jill A., additional, Perry, Jerilyn G., additional, Shelley, Stephen E., additional, Fish, Patrick J., additional, Scott, Michael H., additional, Dixon, James A., additional, Walsh, Shannon R., additional, Ozpirincci, Philomina M., additional, Tebon, Brenda L., additional, Moyle, Marcia J., additional, Pavlica, Michael R., additional, Matta, Noelle S., additional, Brubaker, Cristina M., additional, Backer, Alyson B., additional, Bhagat, Neelakshi, additional, Fay, Catherine, additional, Mikheyeva, Tatiana, additional, Lazar, Michael, additional, Ellenberger, Janie D., additional, Malpica, Beth, additional, Brucker, Alexander J., additional, Kim, Benjamin J., additional, VanderBeek, Brian L., additional, Drossner, Sheri, additional, DuPont, Joan C., additional, Salvo, Rebecca, additional, Engelhard, Stephanie B., additional, Berger, Jim M., additional, Morales, Sara, additional, Serpentine, Beth, additional, Kaufman, Paul L., additional, McCluskey, Jessica D., additional, Wynne, Kathy T., additional, Jordan, Julian, additional, Watson, Brandun, additional, Wirthlin, Robert S., additional, Guglielmo, Eric S., additional, Dittman, Eileen A., additional, Waidelich, Dylan C., additional, Garza, Cristofer J., additional, Stone, Adeline M., additional, Oakes, Ashley Nicole, additional, Suner, Ivan J., additional, Hammer, Mark E., additional, Peden, Marc C., additional, Traynom, Janet R., additional, DenBoer, Rochelle, additional, Vargo, Heidi, additional, Ramsey, Susan, additional, Malzahn, Anita Kim, additional, Jeffres, Debra, additional, Chaudhry, Nauman A., additional, Shah, Sumit P., additional, Haffner, Gregory M., additional, German, Emiliya, additional, Moreau, Shannan, additional, Fox, Laura A., additional, Matteson, Jennifer M., additional, Pelletier, JoAnna L., additional, Fontecchio, Alison, additional, Morse, Emily, additional, McNamara, Greg, additional, Laglivia, Marie Grace, additional, Scherf, Marissa L., additional, LaPre, Angela, additional, Cocilo, Justin A., additional, Das, Arup, additional, Friesen, Linda, additional, Franco, Michele, additional, Lucero, Johnny, additional, Frazier, Melissa, additional, Laviolette, Robert, additional, Mian, Umar Khalil, additional, Riemer, Rebecca L., additional, Koestenblatt, Evelyn, additional, Wolf, Louise V., additional, Kim, Christine, additional, Katkovskaya, Irina, additional, Otoo, Erica, additional, Ellerbe, Kevin A., additional, Boyd, Kenneth, additional, Costa, Caroline, additional, Edwards, Paul Andrew, additional, Gao, Hua, additional, Hessburg, Thomas, additional, Desai, Uday, additional, Murphy, Janet, additional, Monk, Mary K., additional, Hall, Julianne, additional, Mazurek, Melina, additional, Ventimiglia, Katie M., additional, Rusinek, Brian A., additional, Stern, Bradley A., additional, Brouhard, Kris, additional, Weier, Katie M., additional, Allis, Megan, additional, Shaken, Jenny, additional, Massu, Nicole M., additional, Troszak, Tracy A., additional, Burley, David, additional, Bhavsar, Abdhish R., additional, Emerson, Geoffrey G., additional, Jones, Jacob M., additional, Anderson, Tracy A., additional, Gilchrist, Andrea, additional, Peloquin, Matt D., additional, Gaid, Gaid, additional, Vang, Yang, additional, Ryan, Samantha, additional, Vang, Denise, additional, Evans, Alanna C., additional, Scherer, Tonja, additional, Lazarus, Howard S., additional, Bunch, Debra Paige, additional, Davis, Liana C., additional, Booth, Kelly, additional, Trimble, Margaret, additional, Bledsaw, Mary A., additional, Moore, Jay, additional, Rosberger, Daniel F., additional, Groeschel, Sandra, additional, Madry, Miriam A., additional, DiGirolamo, Nikoletta, additional, Pressley, Dustin, additional, Santora, Robert, additional, Gomez, Yenelda M., additional, Olsen, Karl R., additional, Bergren, Robert L., additional, Conrad, P. William, additional, Rath, Pamela P., additional, Vyas, Avni Patel, additional, Liu, Judy C., additional, Merlotti, Lori A., additional, Chamberlin, Jennifer L., additional, Mechling, Holly M., additional, Kelly, Mary E., additional, Marfisi, Kellianne, additional, Yeckel, Kimberly A., additional, Bennett, Veronica L., additional, Schultz, Christina M., additional, Rigoni, Grace A., additional, Walter, Julie, additional, Forish, Missy A., additional, Fec, Amanda, additional, Foreman, Courtney L., additional, Steinberg, David, additional, McBroom, Keith D., additional, Chen, Melvin C., additional, Levy, Marc H., additional, Torres, Waldemar, additional, Jelemensky, Peggy, additional, Raphael, Tara L., additional, Rich, Joann, additional, Sneath, Mark, additional, Kinyoun, James L., additional, Vemulakonda, Gurunadh Atmaram, additional, Rath, Susan A., additional, Ernst, Patricia K., additional, Pettingill, Juli A., additional, Jones, Ronald C., additional, Clifton, Brad C., additional, Leslie, James D., additional, Solomon, Sharon D., additional, Levin, Lisa K., additional, Donohue, Deborah, additional, Frey, Mary, additional, Larez, Lorena, additional, Murray, Keisha, additional, Denbow, Rita L., additional, Graul, Janis, additional, Emmert, David, additional, Herring, Charles, additional, Rhoton, Nick, additional, Belz, Joe, additional, Lyon, Alice T., additional, Mirza, Rukhsana G., additional, Krug, Amanda M., additional, Ramirez, Carmen, additional, Kaminski, Lori, additional, Castro-Malek, Anna Liza M., additional, Mills, Amber N., additional, Rozenbajgier, Zuzanna, additional, Skelly, Marriner L., additional, Simjanoski, Evica, additional, Degillio, Andrea R., additional, Lim, Jennifer I., additional, Chau, Felix Y., additional, Niec, Marcia, additional, Johnson, Tametha, additional, Ovando, Yesenia, additional, Janowicz, Mark, additional, Carroll, Catherine, additional, Gross, Jeffrey G., additional, Fishburne, Barron C., additional, Flowers, Amy M., additional, Stroman, Riley, additional, Ochieng, Christen, additional, McDowell, Angelique S.A., additional, Paul, Ally M., additional, Price, Randall L., additional, Drouilhet, John H., additional, Lacaden, Erica N., additional, Nobler, Deborah J., additional, Cummings, Howard L., additional, Long, Deanna Jo, additional, McCord, Ben, additional, Robinson, Jason, additional, Swift, Jamie, additional, Maynard, Julie P., additional, Pahk, Patricia J., additional, Palmer-Dwore, Hannah, additional, Dave, Dipali H., additional, Pacheco, Mariebelle, additional, Galati, Barbara A., additional, Simpson, Eneil, additional, Barkmeier, Andrew J., additional, Vogen, Diane L., additional, Berg, Karin A., additional, Howard, Shannon L., additional, Burrington, Jean M., additional, Morgan, Jessica Ann, additional, Overend, Joan T., additional, Goddard, Shannon, additional, Lewison, Denise M., additional, Tesmer, Jaime L., additional, Greven, Craig Michael, additional, Fish, Joan, additional, Everhart, Cara, additional, Clark, Mark D., additional, Miller, David T., additional, Hubbard, George Baker, additional, Yan, Jiong, additional, Cribbs, Blaine E., additional, Curtis, Linda T., additional, Brower, Judy L., additional, Dobbs, Jannah L., additional, Jordan, Debora J., additional, Ahmad, Baseer U., additional, Huang, Suber S., additional, Sedlacek, Hillary M., additional, Hornsby, Cherie L., additional, Ferguson, Lisa P., additional, Carlton, Kathy, additional, Sholtis, Kelly A., additional, Allchin, Peggy, additional, Clow, Claudia, additional, Harrod, Mark A., additional, Pankhurst, Geoffrey, additional, Baum-Rawraway, Irit, additional, Hrvatin, Stacie A., additional, Gentile, Ronald C., additional, Yang, Alex, additional, Carrasquillo-Boyd, Wanda, additional, Masini, Robert, additional, Samy, Chander N., additional, Kraut, Robert J., additional, Shirley, Kathy, additional, Corso, Linsey, additional, Ely, Karen, additional, Scala, Elizabeth, additional, Gross, Stewart, additional, Alava, Vanessa, additional, Margalit, Eyal, additional, Neely, Donna G., additional, Blaiotta, Maria, additional, Hagensen, Lori, additional, Harris, April E., additional, Lennon, Rita L., additional, Cota, Denice R., additional, Wilson, Larry, additional, Aiello, Lloyd P., additional, Beck, Roy W., additional, Bressler, Susan B., additional, Chalam, Kakarla V., additional, Danis, Ronald P., additional, Arnold-Bush, Bambi J., additional, Ferris, Frederick, additional, Almukhtar, Talat, additional, Dale, Brian B., additional, Baptista, Alyssa, additional, Connor, Crystal, additional, Conner, Jasmine, additional, Constantine, Sharon R., additional, Dowling, Kimberly, additional, Dupre, Simone S., additional, Ayala, Allison R., additional, Huggins, Meagan L., additional, Inusah, Seidu, additional, Johnson, Paula A., additional, Loggins, Brenda L., additional, McClellan, Shannon L., additional, Melia, Michele, additional, Battle, Eureca, additional, Stockdale, Cynthia R., additional, Stanley, Danielle, additional, Jaffe, Glenn, additional, Balsley, Brannon, additional, Barbas, Michael, additional, Burns, Russell, additional, Busian, Dee, additional, Ebersohl, Ryan, additional, Heydary, Cynthia, additional, McEwan, Sasha, additional, Myers, Justin, additional, Robertson, Amanda, additional, Shields, Kelly, additional, Thompson, Garrett, additional, Winter, Katrina, additional, Young, Ellen, additional, Davis, Matthew D., additional, Huang, Yijun, additional, Blodi, Barbara, additional, Domalpally, Amitha, additional, Reimers, James, additional, Vargo, Pamela, additional, Wabers, Hugh, additional, Myers, Dawn, additional, Lawrence, Daniel, additional, Allan, James, additional, Jampol, Lee M., additional, Antoszyk, Andrew, additional, Friedman, Scott, additional, Scott, Ingrid U., additional, Schron, Eleanor, additional, Everett, Donald F., additional, Miskala, Päivi H., additional, Connett, John, additional, Abrams, Gary, additional, Barnbaum, Deborah R., additional, Flynn, Harry, additional, Weinstock, Ruth S., additional, Wilkinson, Charles P., additional, Wisniewski, Stephen, additional, Genuth, Saul, additional, Frank, Robert, additional, Ferris, Frederick L., additional, Jaffe, Glenn J., additional, Bhavsar, Abdhish, additional, Googe, Joseph, additional, Lauer, Andreas, additional, and McClain, Ashley, additional

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2018
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31. Effect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity: A Randomized Clinical Trial.

Author

Baker, Carl W., Glassman, Adam R., Beaulieu, Wesley T., Antoszyk, Andrew N., Browning, David J., Chalam, Kakarla V., Grover, Sandeep, Jampol, Lee M., Jhaveri, Chirag D., Melia, Michele, Stockdale, Cynthia R., Martin, Daniel F., Sun, Jennifer K., and DRCR Retina Network

Abstract

Importance: Intravitreous injections of antivascular endothelial growth factor agents are effective for treating diabetic macular edema (DME) involving the center of the macula (center-involved DME [CI-DME]) with visual acuity impairment (20/32 or worse). The best approach to treating patients with CI-DME and good visual acuity (20/25 or better) is unknown.Objective: To compare vision loss at 2 years among eyes initially managed with aflibercept, laser photocoagulation, or observation.Design, Setting, and Participants: Randomized clinical trial conducted at 91 US and Canadian sites among 702 adults with type 1 or type 2 diabetes. Participants had 1 study eye with CI-DME and visual acuity of 20/25 or better. The first participant was randomized on November 8, 2013, and the final date of follow-up was September 11, 2018.Interventions: Eyes were randomly assigned to 2.0 mg of intravitreous aflibercept (n = 226) as frequently as every 4 weeks, focal/grid laser photocoagulation (n = 240), or observation (n = 236). Aflibercept was required for eyes in the laser photocoagulation or observation groups that had decreased visual acuity from baseline by at least 10 letters (≥ 2 lines on an eye chart) at any visit or by 5 to 9 letters (1-2 lines) at 2 consecutive visits.Main Outcomes and Measures: The primary outcome was at least a 5-letter visual acuity decrease from baseline at 2 years. Antiplatelet Trialists' Collaboration adverse events (defined as myocardial infarction, stroke, or vascular or unknown death) were reported.Results: Among 702 randomized participants (mean age, 59 years; 38% female [n=264]), 625 of 681 (92% excluding deaths) completed the 2-year visit. For eyes with visual acuity that decreased from baseline, aflibercept was initiated in 25% (60/240) and 34% (80/236) in the laser photocoagulation and observation groups, respectively. At 2 years, the percentage of eyes with at least a 5-letter visual acuity decrease was 16% (33/205), 17% (36/212), and 19% (39/208) in the aflibercept, laser photocoagulation, and observation groups, respectively (aflibercept vs laser photocoagulation risk difference, -2% [95% CI, -9% to 5%]; relative risk, 0.88 [95% CI, 0.57-1.35; P = .79]; aflibercept vs observation risk difference, -3% [95% CI, -11% to 4%]; relative risk, 0.83 [95% CI, 0.55-1.27; P = .79]; laser photocoagulation vs observation risk difference, -1% [95% CI, -9% to 6%]; relative risk, 0.95 [95% CI, 0.64-1.41; P = .79]). Antiplatelet Trialists' Collaboration vascular events occurred in 15 (7%), 13 (5%), and 8 (3%) participants in the aflibercept, laser photocoagulation, and observation groups.Conclusions and Relevance: Among eyes with CI-DME and good visual acuity, there was no significant difference in vision loss at 2 years whether eyes were initially managed with aflibercept or with laser photocoagulation or observation and given aflibercept only if visual acuity worsened. Observation without treatment unless visual acuity worsens may be a reasonable strategy for CI-DME.Trial Registration: ClinicalTrials.gov Identifier: NCT01909791. [ABSTRACT FROM AUTHOR]

Published
2019
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32. Five-Year Outcomes of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial.

Author

Gross, Jeffrey G., Glassman, Adam R., Liu, Danni, Sun, Jennifer K., Antoszyk, Andrew N., Baker, Carl W., Bressler, Neil M., Elman, Michael J., Ferris III, Frederick L., Gardner, Thomas W., Jampol, Lee M., Martin, Daniel F., Melia, Michele, Stockdale, Cynthia R., Beck, Roy W., Ferris, Frederick L 3rd, and Diabetic Retinopathy Clinical Research Network

Published
2018
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33. Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials

Author

Willoughby, Alex S., primary, Ying, Gui-shuang, additional, Toth, Cynthia A., additional, Maguire, Maureen G., additional, Burns, Russell E., additional, Grunwald, Juan E., additional, Daniel, Ebenezer, additional, Jaffe, Glenn J., additional, Williams, David F., additional, Beardsley, Sara, additional, Bennett, Steven, additional, Cantrill, Herbert, additional, Chan-Tram, Carmen, additional, Cheshier, Holly, additional, Damato, Kathyrn, additional, Davies, John, additional, Dev, Sundeep, additional, Enloe, Julianne, additional, Follano, Gennaro, additional, Gilbert, Peggy, additional, Johnson, Jill, additional, Jones, Tori, additional, Mayleben, Lisa, additional, Mittra, Robert, additional, Moos, Martha, additional, Neist, Ryan, additional, Oestreich, Neal, additional, Quiram, Polly, additional, Ramsay, Robert, additional, Ryan, Edwin, additional, Schindeldecker, Stephanie, additional, Snater, John, additional, Steele, Trenise, additional, Selders, Dwight, additional, Tonsfeldt, Jessica, additional, Valardi, Shelly, additional, Fish, Gary Edd, additional, Aguado, Hank A., additional, Arceneaux, Sally, additional, Arnwine, Jean, additional, Bell, Kim, additional, Bell, Tina, additional, Boleman, Bob, additional, Bradley, Patricia, additional, Callanan, David, additional, Coors, Lori, additional, Creighton, Jodi, additional, Crew, Timothy, additional, Cummings, Kimberly, additional, Dock, Christopher, additional, Duignan, Karen, additional, Fuller, Dwain, additional, Gray, Keith, additional, Hendrix, Betsy, additional, Hesse, Nicholas, additional, Jaramillo, Diana, additional, Jost, Bradley, additional, Lash, Sandy, additional, Lonsdale, Laura, additional, Mackens, Michael, additional, Mutz, Karin, additional, Potts, Michael, additional, Sanchez, Brenda, additional, Snyder, William, additional, Solley, Wayne, additional, Tarter, Carrie, additional, Wang, Robert, additional, Williams, Patrick, additional, Perkins, Stephen L., additional, Anderson, Nicholas, additional, Arnold, Ann, additional, Blais, Paul, additional, Googe, Joseph, additional, Higdon, Tina T., additional, Hunt, Cecile, additional, Johnson, Mary, additional, Miller, James, additional, Moore, Misty, additional, Morris, Charity K., additional, Morris, Christopher, additional, Oelrich, Sarah, additional, Oliver, Kristina, additional, Seitz, Vicky, additional, Whetstone, Jerry, additional, Doft, Bernard H., additional, Bedel, Jay, additional, Bergren, Robert, additional, Borthwick, Ann, additional, Conrad, Paul, additional, Fec, Amanda, additional, Fulwylie, Christina, additional, Ingram, Willia, additional, Latham, Shawnique, additional, Lester, Gina, additional, Liu, Judy, additional, Lobes, Louis, additional, Lucko, Nicole M., additional, Mechling, Holly, additional, Merlotti, Lori, additional, McBroom, Keith, additional, Olsen, Karl, additional, Puskas, Danielle, additional, Rath, Pamela, additional, Schmucker, Maria, additional, Schueckler, Lynn, additional, Schultz, Christina, additional, Shultz, Heather, additional, Steinberg, David, additional, Vyas, Avni, additional, Whale, Kim, additional, Yeckel, Kimberly, additional, Orth, David H., additional, Arredondo, Linda S., additional, Brown, Susan, additional, Ciscato, Barbara J., additional, Civantos, Joseph M., additional, Figliulo, Celeste, additional, Hasan, Sohail, additional, Kosinski, Belinda, additional, Muir, Dan, additional, Nelson, Kiersten, additional, Packo, Kirk, additional, Pollack, John S., additional, Rezaei, Kourous, additional, Shelton, Gina, additional, Townsend-Patrick, Shannya, additional, Walsh, Marian, additional, Richard McDonald, H., additional, Ansari, Nina, additional, Bye, Amanda, additional, Fu, Arthur D., additional, Grout, Sean, additional, Indermill, Chad, additional, Johnson, Robert N., additional, Michael Jumper, J., additional, Linares, Silvia, additional, Lujan, Brandon J., additional, Munden, Ames, additional, Persons, Meredith, additional, Rodriguez, Rosa, additional, Rose, Jennifer M., additional, Teske, Brandi, additional, Urias, Yesmin, additional, Young, Stephen, additional, Dreyer, Richard F., additional, Daniel, Howard, additional, Connaughton, Michele, additional, Handelman, Irvin, additional, Hobbs, Stephen, additional, Hoerner, Christine, additional, Hudson, Dawn, additional, Kopfer, Marcia, additional, Lee, Michael, additional, Lemley, Craig, additional, Logan, Joe, additional, Ma, Colin, additional, Mallet, Christophe, additional, Milliron, Amanda, additional, Peters, Mark, additional, Wohlsein, Harry, additional, Pearlman, Joel A., additional, Andrews, Margo, additional, Bartlett, Melissa, additional, Carlson, Nanette, additional, Cox, Emily, additional, Equi, Robert, additional, Gonzalez, Marta, additional, Griffin, Sophia, additional, Hogue, Fran, additional, Kennedy, Lance, additional, Kryuchkov, Lana, additional, Lopez, Carmen, additional, Lopez, Danny, additional, Luevano, Bertha, additional, McKenna, Erin, additional, Patel, Arun, additional, Reed, Brian, additional, Secor, Nyla, additional, Sison, Iris R., additional, Tsai, Tony, additional, Varghis, Nina, additional, Waller, Brooke, additional, Wendel, Robert, additional, Yebra, Reina, additional, Roth, Daniel B., additional, Deinzer, Jane, additional, Fine, Howard, additional, Green, Flory, additional, Green, Stuart, additional, Keyser, Bruce, additional, Leff, Steven, additional, Leviton, Amy, additional, Martir, Amy, additional, Mosenthine, Kristin, additional, Muscle, Starr, additional, Okoren, Linda, additional, Parker, Sandy, additional, Prenner, Jonathan, additional, Price, Nancy, additional, Rogers, Deana, additional, Rosas, Linda, additional, Schlosser, Alex, additional, Studenko, Loretta, additional, Tantum, Thea, additional, Wheatley, Harold, additional, Trese, Michael T., additional, Aaberg, Thomas, additional, Bezaire, Denis, additional, Bridges, Craig, additional, Bryant, Doug, additional, Capone, Antonio, additional, Coleman, Michelle, additional, Consolo, Christina, additional, Cook, Cindy, additional, DuLong, Candice, additional, Garretson, Bruce, additional, Grooten, Tracy, additional, Hammersley, Julie, additional, Hassan, Tarek, additional, Jessick, Heather, additional, Jones, Nanette, additional, Kinsman, Crystal, additional, Krumlauf, Jennifer, additional, Lewis, Sandy, additional, Locke, Heather, additional, Margherio, Alan, additional, Markus, Debra, additional, Marsh, Tanya, additional, Neal, Serena, additional, Noffke, Amy, additional, Oh, Kean, additional, Pence, Clarence, additional, Preston, Lisa, additional, Raphaelian, Paul, additional, Regan, Virginia R., additional, Roberts, Peter, additional, Ruby, Alan, additional, Sarrafizadeh, Ramin, additional, Scherf, Marissa, additional, Scott, Sarita, additional, Sneed, Scott, additional, Staples, Lisa, additional, Terry, Brad, additional, Trese, Matthew T., additional, Videtich, Joan, additional, Williams, George, additional, Zajechowski, Mary, additional, Joseph, Daniel P., additional, Blinder, Kevin, additional, Boyd, Lynda, additional, Buckley, Sarah, additional, Crow, Meaghan, additional, Dinatale, Amanda, additional, Engelbrecht, Nicholas, additional, Forke, Bridget, additional, Gabel, Dana, additional, Grand, Gilbert, additional, Grillion-Cerone, Jennifer, additional, Holekamp, Nancy, additional, Kelly, Charlotte, additional, Nobel, Ginny, additional, Pepple, Kelly, additional, Raeber, Matt, additional, Kumar Rao, P., additional, Ressel, Tammy, additional, Schremp, Steven, additional, Sgorlon, Merrilee, additional, Shears, Shantia, additional, Thomas, Matthew, additional, Timma, Cathy, additional, Vaughn, Annette, additional, Walters, Carolyn, additional, Weeks, Rhonda, additional, Wehmeier, Jarrod, additional, Wright, Tim, additional, Berinstein, Daniel M., additional, Ayyad, Aida, additional, Barazi, Mohammed K., additional, Bickhart, Erica, additional, Brady, Tracey, additional, Byank, Lisa, additional, Cronise, Alysia, additional, Denny, Vanessa, additional, Dunn, Courtney, additional, Flory, Michael, additional, Frantz, Robert, additional, Garfinkel, Richard A., additional, Gilbert, William, additional, Lai, Michael M., additional, Melamud, Alexander, additional, Newgen, Janine, additional, Newton, Shamekia, additional, Oliver, Debbie, additional, Osman, Michael, additional, Sanders, Reginald, additional, von Fricken, Manfred, additional, Dugel, Pravin, additional, Arenas, Sandra, additional, Balea, Gabe, additional, Bartoli, Dayna, additional, Bucci, John, additional, Cornelius, Jennifer A., additional, Dickens, Scheleen, additional, Doherty, Don, additional, Dunlap, Heather, additional, Goldenberg, David, additional, Jamal, Karim, additional, Jimenez, Norma, additional, Kavanagh, Nicole, additional, Kunimoto, Derek, additional, Martin, John, additional, Miner, Jessica, additional, Mobley, Sarah, additional, Park, Donald, additional, Quinlan, Edward, additional, Sipperley, Jack, additional, Slagle, Carol, additional, Smith, Danielle, additional, Yafchak, Miguelina, additional, Yager, Rohana, additional, Flaxel, Christina J., additional, Bailey, Steven, additional, Francis, Peter, additional, Howell, Chris, additional, Hwang, Thomas, additional, Ira, Shirley, additional, Klein, Michael, additional, Lauer, Andreas, additional, Liesegang, Teresa, additional, Lundquist, Ann, additional, Nolte, Sarah, additional, Nolte, Susan K., additional, Pickell, Scott, additional, Pope, Susan, additional, Rossi, Joseph, additional, Schain, Mitchell, additional, Steinkamp, Peter, additional, Toomey, Maureen D., additional, Vahrenwald, Debora, additional, West, Kelly, additional, Hubbard, Baker, additional, Andelman, Stacey, additional, Bergstrom, Chris, additional, Brower, Judy, additional, Cribbs, Blaine, additional, Curtis, Linda, additional, Dobbs, Jannah, additional, DuBois, Lindreth, additional, Gaultney, Jessica, additional, Gibbs, Deborah, additional, Jordan, Debora, additional, Leef, Donna, additional, Martin, Daniel F., additional, Myles, Robert, additional, Olsen, Timothy, additional, Schwent, Bryan, additional, Srivastava, Sunil, additional, Waldron, Rhonda, additional, Antoszyk, Andrew N., additional, Balasubramaniam, Uma, additional, Brooks, Danielle, additional, Brown, Justin, additional, Browning, David, additional, Clark, Loraine, additional, Ennis, Sarah, additional, Held, Susannah, additional, Helms, Jennifer V., additional, Herby, Jenna, additional, Karow, Angie, additional, Leotaud, Pearl, additional, Massimino, Caterina, additional, McClain, Donna, additional, McOwen, Michael, additional, Mindel, Jennifer, additional, Pereira, Candace, additional, Pierce, Rachel, additional, Powers, Michele, additional, Price, Angela, additional, Rohrer, Jason, additional, Sanders, Jason, additional, Avery, Robert L., additional, Avery, Kelly, additional, Basefsky, Jessica, additional, Beckner, Liz, additional, Castellarin, Alessandro, additional, Couvillion, Stephen, additional, Giust, Jack, additional, Giust, Matthew, additional, Nasir, Maan, additional, Pieramici, Dante, additional, Rabena, Melvin, additional, Risard, Sarah, additional, See, Robert, additional, Smith, Jerry, additional, Wan, Lisha, additional, Bakri, Sophie J., additional, Abu-Yaghi, Nakhleh, additional, Barkmeier, Andrew, additional, Berg, Karin, additional, Burrington, Jean, additional, Edwards, Albert, additional, Goddard, Shannon, additional, Howard, Shannon, additional, Iezzi, Raymond, additional, Lewison, Denise, additional, Link, Thomas, additional, McCannel, Colin A., additional, Overend, Joan, additional, Pach, John, additional, Ruszczyk, Margaret, additional, Shultz, Ryan, additional, Stephan, Cindy, additional, Vogen, Diane, additional, Bradford, Reagan H., additional, Bergman, Vanessa, additional, Burris, Russ, additional, Butt, Amanda, additional, Daniels, Beth, additional, Dwiggins, Connie, additional, Fransen, Stephen, additional, Guerrero, Tiffany, additional, Haivala, Darin, additional, Harris, Amy, additional, Icks, Sonny, additional, Kingsley, Ronald, additional, Redden, Lena, additional, Richmond, Rob, additional, Ross, Brittany, additional, White, Kammerin, additional, Youngberg, Misty, additional, Topping, Trexler M., additional, Bennett, Steve, additional, Chong, Sandy, additional, Ciotti, Mary, additional, Cleary, Tina, additional, Corey, Emily, additional, Donovan, Dennis, additional, Frederick, Albert, additional, Freese, Lesley, additional, Graham, Margaret, additional, Gud, Natalya, additional, Howard, Taneika, additional, Jones, Mike, additional, Morley, Michael, additional, Moses, Katie, additional, Stone, Jen, additional, Ty, Robin, additional, Wiegand, Torsten, additional, Williams, Lindsey, additional, Winder, Beth, additional, Awh, Carl C., additional, Amonette, Michelle, additional, Arrindell, Everton, additional, Beck, Dena, additional, Busbee, Brandon, additional, Dilback, Amy, additional, Downs, Sara, additional, Guidry, Allison, additional, Gutow, Gary, additional, Hardin, Jackey, additional, Hines, Sarah, additional, Hutchins, Emily, additional, LaCivita, Kim, additional, Lester, Ashley, additional, Malott, Larry, additional, McCain, MaryAnn, additional, Miracle, Jayme, additional, Moffat, Kenneth, additional, Palazzotta, Lacy, additional, Robinson, Kelly, additional, Sonkin, Peter, additional, Travis, Alecia, additional, Wallace, Roy Trent, additional, Winters, Kelly J., additional, Wray, Julia, additional, Harris, April E., additional, Bunnell, Mari, additional, Crooks, Katrina, additional, Fitzgerald, Rebecca, additional, Javid, Cameron, additional, Kew, Corin, additional, Kill, Erica, additional, Kline, Patricia, additional, Kreienkamp, Janet, additional, Martinez, Maricruz, additional, Ann Moore, Roy, additional, Saavedra, Egbert, additional, Taylor, LuAnne, additional, Walsh, Mark, additional, Wilson, Larry, additional, Ciulla, Thomas A., additional, Coyle, Ellen, additional, Harrington, Tonya, additional, Harris, Charlotte, additional, Hood, Cindi, additional, Kerr, Ingrid, additional, Maturi, Raj, additional, Moore, Dawn, additional, Morrow, Stephanie, additional, Savage, Jennifer, additional, Sink, Bethany, additional, Steele, Tom, additional, Thukral, Neelam, additional, Wilburn, Janet, additional, Walker, Joseph P., additional, Banks, Jennifer, additional, Ciampaglia, Debbie, additional, Dyshanowitz, Danielle, additional, Frederick, Jennifer, additional, Tom Ghuman, A., additional, Grodin, Richard, additional, Kiesel, Cheryl, additional, Knips, Eileen, additional, McCue, Jonathan, additional, Ortiz, Maria, additional, Peters, Crystal, additional, Raskauskas, Paul, additional, Schoeman, Etienne, additional, Sharma, Ashish, additional, Wing, Glenn, additional, Youngblood, Rebecca, additional, Chandra, Suresh R., additional, Altaweel, Michael, additional, Blodi, Barbara, additional, Burke, Kathryn, additional, Dietzman, Kristine A., additional, Gottlieb, Justin, additional, Knutson, Gene, additional, Krolnik, Denise, additional, Michael Nork, T., additional, Olson, Shelly, additional, Peterson, John, additional, Reed, Sandra, additional, Soderling, Barbara, additional, Somers, Guy, additional, Stevens, Thomas, additional, Wealti, Angela, additional, Bearelly, Srilaxmi, additional, Branchaud, Brenda, additional, Bryant, Joyce W., additional, Crowell, Sara, additional, Fekrat, Sharon, additional, Gammage, Merritt, additional, Harrison, Cheala, additional, Jones, Sarah, additional, McClain, Noreen, additional, McCuen, Brooks, additional, Mruthyunjaya, Prithvi, additional, Queen, Jeanne, additional, Sarin, Neeru, additional, Skalak, Cindy, additional, Skelly, Marriner, additional, Suner, Ivan, additional, Tomany, Ronnie, additional, Welch, Lauren, additional, Park, Susanna S., additional, Cassidy, Allison, additional, Chandra, Karishma, additional, Good, Idalew, additional, Imson, Katrina, additional, Kaur, Sashi, additional, Metzler, Helen, additional, Morse, Lawrence, additional, Redenbo, Ellen, additional, Salvador, Marisa, additional, Telander, David, additional, Thomas, Mark, additional, Wallace, Cindy, additional, Barr, Charles C., additional, Battcher, Amanda, additional, Bottorff, Michelle, additional, Chasteen, Mary, additional, Clark, Kelly, additional, Denning, Diane, additional, Schoen, Debra, additional, Schultz, Amy, additional, Tempel, Evie, additional, Wheeler, Lisa, additional, Whittington, Greg K., additional, Stone, Thomas W., additional, Blevins, Todd, additional, Buck, Michelle, additional, Cruz, Lynn, additional, Heath, Wanda, additional, Holcomb, Diana, additional, Isernhagen, Rick, additional, Kidd, Terri, additional, Kitchens, John, additional, Sears, Cathy, additional, Slade, Ed, additional, Van Arsdall, Jeanne, additional, VanHoose, Brenda, additional, Wolfe, Jenny, additional, Wood, William, additional, Zilis, John, additional, Crooks, Carol, additional, Disney, Larry, additional, Liu, Mimi, additional, Petty, Stephen, additional, Sall, Sandra, additional, Folk, James C., additional, Aly, Tracy, additional, Brotherton, Abby, additional, Critser, Douglas, additional, Hinz, Connie J., additional, Karakas, Stefani, additional, Kirschner, Valerie, additional, Lester, Cheyanne, additional, Montague, Cindy, additional, Russell, Stephen, additional, Stockman, Heather, additional, Taylor, Barbara, additional, Verdick, Randy, additional, Walshire, Jean, additional, Thompson, John T., additional, Connell, Barbara, additional, Constantine, Maryanth, additional, Davis, John L., additional, Holsapple, Gwen, additional, Hunter, Lisa, additional, Lenane, C. Nicki, additional, Mitchell, Robin, additional, Russel, Leslie, additional, Sjaarda, Raymond, additional, Brown, David M., additional, Benz, Matthew, additional, Burns, Llewellyn, additional, Carranza, JoLene G., additional, Fish, Richard, additional, Goates, Debra, additional, Hay, Shayla, additional, Jeffers, Theresa, additional, Kegley, Eric, additional, Kubecka, Dallas, additional, McGilvra, Stacy, additional, Richter, Beau, additional, Sneed, Veronica, additional, Stoever, Cary, additional, Tellez, Isabell, additional, Wong, Tien, additional, Kim, Ivana, additional, Andreoli, Christopher, additional, Barresi, Leslie, additional, Brett, Sarah, additional, Callahan, Charlene, additional, Capaccioli, Karen, additional, Carli, William, additional, Coppola, Matthew, additional, Emmanuel, Nicholas, additional, Evans, Claudia, additional, Fagan, Anna, additional, Grillo, Marcia, additional, Head, John, additional, Kieser, Troy, additional, Lee, Elaine, additional, Lord, Ursula, additional, Miretsky, Edward, additional, Palitsch, Kate, additional, Petrin, Todd, additional, Reader, Liz, additional, Reznichenko, Svetlana, additional, Robertson, Mary, additional, Smith, Justin, additional, Vavvas, Demetrios, additional, Wells, John, additional, Cahill, Cassie, additional, Lloyd Clark, W., additional, Henry, Kayla, additional, Johnson, David, additional, Miller, Peggy, additional, Oliver, LaDetrick, additional, Spivey, Robbin, additional, Swinford, Tiffany, additional, Taylor, Mallie, additional, Lambert, Michael, additional, Chase, Kris, additional, Fredrickson, Debbie, additional, Khawly, Joseph, additional, Lazarte, Valerie, additional, Lowd, Donald, additional, Miller, Pam, additional, Willis, Arthur, additional, Ferrone, Philip J., additional, Almonte, Miguel, additional, Arnott, Rachel, additional, Aviles, Ingrid, additional, Carbon, Sheri, additional, Chitjian, Michael, additional, DAmore, Kristen, additional, Elliott, Christin, additional, Fastenberg, David, additional, Golub, Barry, additional, Graham, Kenneth, additional, Lavorna, AnnMarie, additional, Murphy, Laura, additional, Palomo, Amanda, additional, Puglisi, Christina, additional, Rhee, David, additional, Romero, Juan, additional, Rosenblatt, Brett, additional, Salcedo, Glenda, additional, Schlameuss, Marianne, additional, Shakin, Eric, additional, Sookhai, Vasanti, additional, Kaiser, Richard, additional, Affel, Elizabeth, additional, Brown, Gary, additional, Centinaro, Christina, additional, Fine, Deborah, additional, Fineman, Mitchell, additional, Formoso, Michele, additional, Garg, Sunir, additional, Grande, Lisa, additional, Herbert, Carolyn, additional, Ho, Allen, additional, Hsu, Jason, additional, Jay, Maryann, additional, Lavetsky, Lisa, additional, Liebenbaum, Elaine, additional, Maguire, Joseph, additional, Monsonego, Julia, additional, O'Connor, Lucia, additional, Pierce, Lisa, additional, Regillo, Carl, additional, Rosario, Maria, additional, Spirn, Marc, additional, Vander, James, additional, Walsh, Jennifer, additional, Davidorf, Frederick H., additional, Barnett, Amanda, additional, Chang, Susie, additional, Christoforidis, John, additional, Elliott, Joy, additional, Justice, Heather, additional, Letson, Alan, additional, McKinney, Kathryne, additional, Perry, Jeri, additional, Salerno, Jill A., additional, Savage, Scott, additional, Shelley, Stephen, additional, Singerman, Lawrence J., additional, Coney, Joseph, additional, DuBois, John, additional, DuBois, Kimberly, additional, Greanoff, Gregg, additional, Himmelman, Dianne, additional, Ilc, Mary, additional, Mcnamara, Elizabeth, additional, Novak, Michael, additional, Pendergast, Scott, additional, Rath, Susan, additional, Smith-Brewer, Sheila, additional, Tanner, Vivian, additional, Weiss, Diane E., additional, Zegarra, Hernando, additional, Halperin, Lawrence, additional, Aramayo, Patricia, additional, Dhalla, Mandeep, additional, Fernandez, Brian, additional, Fernandez, Cindy, additional, Lopez, Jaclyn, additional, Lopez, Monica, additional, Mariano, Jamie, additional, Murphy, Kellie, additional, Sherley, Clifford, additional, Veksler, Rita, additional, Rahhal, Firas, additional, Babikian, Razmig, additional, Boyer, David, additional, Hami, Sepideh, additional, Kessinger, Jeff, additional, Kurokouchi, Janet, additional, Mukarram, Saba, additional, Pachman, Sarah, additional, Protacio, Eric, additional, Sierra, Julio, additional, Tabandeh, Homayoun, additional, Zamboni, Adam, additional, Elman, Michael, additional, Belz, Jennifer, additional, Butcher, Tammy, additional, Cain, Theresa, additional, Coffey, Teresa, additional, Firestone, Dena, additional, Gore, Nancy, additional, Singletary, Pamela, additional, Sotirakos, Peter, additional, Starr, JoAnn, additional, Meredith, Travis A., additional, Barnhart, Cassandra J., additional, Cantrell, Debra, additional, Esquejo-Leon, RonaLyn, additional, Houghton, Odette, additional, Kaur, Harpreet, additional, NDure, Fatoumatta, additional, Glatzer, Ronald, additional, Joffe, Leonard, additional, Schindler, Reid, additional, Fine, Stuart L., additional, Katz, Marilyn, additional, Brightwell-Arnold, Mary, additional, Glaser, Ruchira, additional, Hall, Judith, additional, Harkins, Sandra, additional, Huang, Jiayan, additional, Khvatov, Alexander, additional, McWilliams, Kathy, additional, Peskin, Ellen, additional, Pistilli, Maxwell, additional, Ryan, Susan, additional, Schnader, Allison, additional, Ying, Gui-Shuang, additional, Jaffe, Glenn, additional, Afrani-Sakyi, Jennifer, additional, Balsley, Brannon, additional, Bennett, Linda S., additional, Brooks, Adam, additional, Brower-Lingsch, Adrienne, additional, Bruce, Lori, additional, Burns, Russell, additional, Busian, Dee, additional, Choong, John, additional, Cloaninger, Lindsey, additional, DeCroos, Francis Char, additional, DuBois, Emily, additional, El-Dairi, Mays, additional, Gach, Sarah, additional, Hall, Katelyn, additional, Hawks, Terry, additional, Huang, ChengChenh, additional, Heydary, Cindy, additional, Ho, Alexander, additional, Kini, Shashi, additional, McCall, Michelle, additional, Muhammad, Daaimah, additional, Nicholson, Jayne, additional, Rieves, Pamela, additional, Shields, Kelly, additional, Specker, Adam, additional, Stinnett, Sandra, additional, Subramaniam, Sujatha, additional, Tenbrink, Patrick, additional, Toth, Cynthia, additional, Towe, Aaron, additional, Welch, Kimberly, additional, Williams, Natasha, additional, Winter, Katrina, additional, Young, Ellen, additional, Alexander, Judith, additional, Flannagan, Elisabeth, additional, Martin, E. Revell, additional, Parker, Candace, additional, Sepielli, Krista, additional, Shannon, Tom, additional, Whearry, Claressa, additional, Redford, Maryann, additional, Kopfer, Marcia R., additional, Ferris, Frederick L., additional, DuPont, Joan, additional, Friedman, Lawrence M., additional, Bressler, Susan B., additional, DeMets, David L., additional, Friedlander, Martin, additional, Johnson, Mark W., additional, Lindblad, Anne, additional, Losordo, Douglas W., additional, and Miller, Franklin G., additional

Published
2015
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34. Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration

Author

Chen, Wei, Stambolian, Dwight, Edwards, Albert O., Branham, Kari E., Othman, Mohammad, Jakobsdottir, Johanna, Tosakulwong, Nirubol, Pericak-Vance, Margaret A., Campochiaro, Peter A., Klein, Michael L., Tan, Perciliz L., Conley, Yvette P., Kanda, Atsuhiro, Kopplin, Laura, Li, Yanming, Augustaitis, Katherine J., Karoukis, Athanasios J., Scott, William K., Agarwal, Anita, Kovach, Jaclyn L., Schwartz, Stephen G., Postel, Eric A., Brooks, Matthew, Baratz, Keith H., Brown, William L., Brucker, Alexander J., Orlin, Anton, Brown, Gary, Ho, Allen, Regillo, Carl, Donoso, Larry, Tian, Lifeng, Kaderli, Brian, Hadley, Dexter, Hagstrom, Stephanie A., Peachey, Neal S., Klein, Ronald, Klein, Barbara E. K., Gotoh, Norimoto, Yamashiro, Kenji, Ferris, Frederick, Fagerness, Jesen A., Reynolds, Robyn, Farrer, Lindsay A., Kim, Ivana K., Miller, Joan W., Cortón, Marta, Carracedo, Angel, Sanchez-Salorio, Manuel, Pugh, Elizabeth W., Doheny, Kimberly F., Brion, Maria, DeAngelis, Margaret M., Weeks, Daniel E., Zack, Donald J., Chew, Emily Y., Heckenlively, John R., Yoshimura, Nagahisa, Iyengar, Sudha K., Francis, Peter J., Katsanis, Nicholas, Seddon, Johanna M., Haines, Jonathan L., Gorin, Michael B., Abecasis, Gonçalo R., Swaroop, Anand, Johnson, Robert N., Ai, Everett, McDonald, H. Richard, Stolarczuk, Margaret, Pavan, Peter Reed, Billiris, Karina K., Iyer, Mohan, Menosky, Matthew M., Pautler, Scott E., Millard, Sharon M., Hubbard, Baker, Aaberg, Thomas, DuBois, Lindy, Lyon, Alice, Anderson-Nelson, Susan, Jampol, Lee M., Weinberg, David V., Muñana, Annie, Rozenbajgier, Zuzanna, Orth, David, Cohen, Jack, MacCumber, Matthew, Figliulo, Celeste, Porcz, Liz, Folk, James, Boldt, H. Culver, Russell, Stephen R., Ivins, Rachel, Hinz, Connie J., Barr, Charles C., Bloom, Steve, Jaegers, Ken, Kritchman, Brian, Whittington, Greg, Heier, Jeffrey, Frederick, Albert R., Morley, Michael G., Topping, Trexler, Davis, Heather L., Bressler, Susan B., Bressler, Neil M., Doll, Warren, Trese, Michael, Capone, Antonio, Garretson, Bruce R., Hassan, Tarek S., Ruby, Alan J., Osentoski, Tammy, McCannel, Colin A., Ruszczyk, Margaret J., Grand, Gilbert, Blinder, Kevin, Holekamp, Nancy M., Joseph, Daniel P., Shah, Gaurav, Nobel, Ginny S., Antoszyk, Andrew N., Browning, David J., Stallings, Alison H, Singerman, Lawrence J., Miller, David, Novak, Michael, Pendergast, Scott, Zegarra, Hernando, Schura, Stephanie A., Smith-Brewer, Sheila, Davidorf, Frederick H., Chambers, Robert, Chorich, Louis, Salerno, Jill, Dreyer, Richard F., Ma, Colin, Kopfer, Marcia R., Wilson, David J., Nolte, Susan K., Grunwald, Juan E., Dunaief, Josh, Fine, Stuart L., Maguire, Albert M., Stoltz, Robert A., McRay, Monique N., Fish, Gary Edd, Anand, Rajiv, Spencer, Rand, Arnwine, Jean, Chandra, Suresh R., Altaweel, Michael, Blodi, Barbara, Gottlieb, Justin, Ip, Michael, Nork, T. Michael, Perry-Raymond, Jennie, Maguire, Maureen G., Brightwell-Arnold, Mary, Harkins, Sandra, Peskin, Ellen, Ying, Gui-Shuang, and Kurinij, Natalie

Subjects
Risk, Genotype, Single-nucleotide polymorphism, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, Macular Degeneration, Polymorphism (computer science), Genetic variation, Humans, Genetic Predisposition to Disease, Allele, Alleles, Genetics, Tissue Inhibitor of Metalloproteinase-3, Multidisciplinary, Case-control study, Chromosome Mapping, Genetic Variation, Biological Sciences, eye diseases, Complement Factor I, ABCA1, Case-Control Studies, biology.protein, Regression Analysis, Lipoproteins, HDL, Genome-Wide Association Study
Abstract

We executed a genome-wide association scan for age-related macular degeneration (AMD) in 2,157 cases and 1,150 controls. Our results validate AMD susceptibility loci near CFH ( P < 10 −75 ), ARMS2 ( P < 10 −59 ), C2/CFB ( P < 10 −20 ), C3 ( P < 10 −9 ), and CFI ( P < 10 −6 ). We compared our top findings with the Tufts/Massachusetts General Hospital genome-wide association study of advanced AMD (821 cases, 1,709 controls) and genotyped 30 promising markers in additional individuals (up to 7,749 cases and 4,625 controls). With these data, we identified a susceptibility locus near TIMP3 (overall P = 1.1 × 10 −11 ), a metalloproteinase involved in degradation of the extracellular matrix and previously implicated in early-onset maculopathy. In addition, our data revealed strong association signals with alleles at two loci ( LIPC , P = 1.3 × 10 −7 ; CETP , P = 7.4 × 10 −7 ) that were previously associated with high-density lipoprotein cholesterol (HDL-c) levels in blood. Consistent with the hypothesis that HDL metabolism is associated with AMD pathogenesis, we also observed association with AMD of HDL-c—associated alleles near LPL ( P = 3.0 × 10 −3 ) and ABCA1 ( P = 5.6 × 10 −4 ). Multilocus analysis including all susceptibility loci showed that 329 of 331 individuals (99%) with the highest-risk genotypes were cases, and 85% of these had advanced AMD. Our studies extend the catalog of AMD associated loci, help identify individuals at high risk of disease, and provide clues about underlying cellular pathways that should eventually lead to new therapies.

Published
2010

39. 4403 A Pilot Multicenter Clinical Study to Evaluate a Mobile Computing System for Remote Monitoring of Retinal Function in Ranibizumab-Treated Neovascular Age-Related Macular Degeneration (AMD)

Author

Kaiser, Peter K., primary, Antoszyk, Andrew N., additional, Eaton, Alexander M., additional, Wang, Yi-Zhong, additional, Sauer, Dirk, additional, Weisberger, Annemarie, additional, Weichselberger, Andreas, additional, Machacek, Matthias, additional, Kuemmel, Anne, additional, Gerstner, Ortrud, additional, and Smith, Craig H., additional

Published
2012
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48. Ranibizumab for Treatment of Neovascular Age-Related Macular Degeneration

Author

Heier, Jeffrey S., primary, Antoszyk, Andrew N., additional, Pavan, Peter Reed, additional, Leff, Steven R., additional, Rosenfeld, Philip J., additional, Ciulla, Thomas A., additional, Dreyer, Richard F., additional, Gentile, Ronald C., additional, Sy, Judy P., additional, Hantsbarger, Gary, additional, and Shams, Naveed, additional

Published
2006
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