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BACKGROUND The efficiency of the mandibular advancement device (MAD) in patients with obstructive sleep apnoea syndrome (OSAS) has been demonstrated. Nevertheless, the behaviour of the upper airway once MAD is placed and titrated, and its correlation with the apnoea-hypopnoea index (AHI) is still under discussion. OBJECTIVES To analyse the morphological changes of the upper airway through a bi- and three-dimensional study and correlate it with the polysomnographic variable, AHI. METHODS Patients were recruited from two different hospitals for the treatment of OSAS with a custom-made MAD. A cone-beam computer tomography and a polysomnography were performed at baseline and once the MAD was titrated. RESULTS A total of 41 patients completed the study. Treatment with MAD reduced the AHI from 22.5 ± 16.8 to 9.2 ± 11.6 (p ≤ .05). There was a significant increase of the total airway volume with MAD from 21.83 ± 7.05 cm3 to 24.19 ± 8.19 cm3 , at the expense of the oropharynx. Moreover, the correlation between the improvement of the AHI and the augmentation of the volume of the upper airway was not statistically significant. CONCLUSIONS The oral device used in this prospective study increased the mean upper pharyngeal airway volume and significantly reduced the AHI. Future studies that measure the muscular tone are needed to completely understand the association between the AHI and the physiological and anatomical response of the upper airway.

Objective: The main objective of this study aimed to evaluate the response to treatment in implants with peri-implantitis regarding the presence or absence of keratinized mucosa. Materials and Methods: One hundred implants with peri-implantitis were treated non-surgically at the Prosthodontics and Occlusion Teaching Unit of the University of Valencia. Records were registered at day zero (recession, bleeding on probing, suppuration, probing depth, bone loss and plaque index), at 1, 3 and 6 months. Results: In both groups, a slight increase in recession and disappearance of suppuration took place, and no bone loss was observed during the following 6 months. However, after an initial reduction, probing depth, bleeding on probing and plaque index increased again in the group without keratinized mucosa (KM). Conclusions: Implants with KM presented better results after non-surgical treatment as well as in their medium-term evolution, although it would be advisable to increase the number of samples in order to achieve greater scientific evidence and standardization in the treatment protocol. Clinical relevance: The role of keratinized mucosa in the development of peri-implantitis has been mentioned in many publications, but less has been emphasized regarding its influence on the success of the treatment of this pathology. The presence of keratinized mucosa has been found to play a key role in the evolution of the non-surgical treatment of peri-implantitis. The amount of keratinized mucosa should be considered in the treatment of peri-implantitis, as well as when planning connective tissue grafts accompanying the decontamination of implants in the absence of keratinized mucosa.

The main objective of this study was to evaluate the response to treatment in implants with peri-implantitis depending on the presence or absence of keratinized mucosa. Materials and Methods: 100 implants with peri-implantitis were treated non-surgically at the Prosthodontics and Occlusion Teaching Unit of the University of Valencia. Records were registered at day zero (recession, bleeding on probing, suppuration, probing depth, bone loss and plaque index), at 1, 3 and 6 months. Results: In both groups a slight increase in recession and disappearance of suppuration took place, and no bone loss was observed during the 6 months. However, both probing depth, bleeding on probing and plaque index, after an initial reduction, increased again in the group without keratinized mucosa (KM). Conclusions: Implants with KM presented better results after non-surgical treatment as well as in their medium-term evolution, although it would be advisable to increase the number of samples in order to achieve greater scientific evidence and standardization in the treatment protocol. Clinical relevance: The role of keratinized mucosa in the development of peri-implantitis has been mentioned in many publications, but less has been emphasized regarding its influence on the success of the treatment of this pathology. The presence of keratinized mucosa has been found to play a determinant role in the evolution of non-surgical treatment of peri-implantitis. The amount of keratinized mucosa should be considered in the treatment of peri-implantitis, as well as when planning connective tissue grafts accompanying the decontamination of implants in the absence of keratinized mucosa.

Background. The effectiveness of mandibular advancement devices has been solidly demonstrated in the past. They are considered a valid alternative treatment to continuous positive airway pressure for patients with obstructive sleep apnea. Nevertheless, the relationship between polysomnographic parameters and the increase in the volume of the upper airway in patients with obstructive sleep apnea syndrome has not been clearly established so far. This study aimed to determine the impact of these oral appliances upon the volume of the airway after the device titration phase and correlate it with the degree of mandibular advancement and the improvement of polysomnographic parameters. Methods. All patients were diagnosed by polysomnography and were treated with a customized, titratable mandibular advancement device. Three-dimensional volumetric measurements were performed using cone beam computed tomography. Results. The present study included 45 patients diagnosed with obstructive sleep apnea hypopnea syndrome (mild in 23 patients, moderate in 11 and severe in 11). Forty-four percent of the patients presented with an apnea hypopnea index &lt, 5/h at the end of treatment. The volume of the upper airway increased an average of 4.3 ± 5.9 cm3, this represents a percentage increase of 20.9%, which was significantly correlated with an apnea hypopnea index and a minimum oxygen saturation improvement. Conclusions. The mandibular advancement device used was found to be effective in improving polysomnographic parameters. Moreover, the oral appliance was able to significantly increase the tridimensional dimensions of the upper airway. Moreover, this finding was correlated with a reduction in the apnea hypopnea index (p = 0.007) and an increase on minimum oxygen saturation (p = 0.033).

Purpose To evaluate the clinicaland biological behavior of full coverage restorations on teeth prepared without finish line during a 4-year follow-up. Methods This prospective study included 149 teeth treated using biologically oriented preparation technique (BOPT). The sample (149 teeth) was divided into two groups: Seventy four teeth restored with crowns, and 75 teeth supporting fixed partial dentures (FPD). Restorations were fabricated with zirconium oxide cores and ceramic coverings. Patients attended regular annual check-ups when probe depth, presence of inflammation with bleeding on probing, presence of plaque, gingival thickness, marginal stability, biological or mechanical complications, and the patient’s level of satisfaction were registered over a 4-year follow-up. Results After the 4-year follow-up, 2.1% of teeth underwent increases in probing depth; 12% of the sample presented inflammation and bleeding on probing; 20% of the restored teeth presented plaque; gingival thickening increased a 32.5%; 98.6% of teeth presented marginal stability; the restoration survival rate was 96.6%, with 2% of biological complications and 1.4% of mechanical complications. General satisfaction score was 80.73. Conclusions Restorations placed on teeth prepared using BOPT present good periodontal behavior, increase of gingival thickening, and marginal stability over a 4-year follow-up. High survival rates after 4 years show that the technique produces predictable outcomes. Clinical significance The BOPT technique is a good treatment option in cases where replacement of an old restoration is required; presenting good periodontal behavior, gingival thickening, and marginal stability.

bjectives. The aim of this study was to analyze the behavior of the periodontal tissues around teeth in the anterior region when restored with zirconia single crowns, using a biologically oriented preparation technique (BOPT), over a 6-year follow-up. Methods. The study investigated tooth-supported single crowns in the anterior region that were fabricated with a zirconia core and feldspathic ceramic covering, in 34 patients. Follow-up analysis took place annually for 6 years, assessing periodontal responses by evaluating the following variables: plaque index (PI), probing depth (PD), gingival index (GI), gingival thickness adjacent to the restoration, and stability of the gingival margin (MS). Any (biological and mechanical) complications were also recorded, as well as the patients’ satisfaction with the treatment. Results. After 6 years’ follow-up, a low mean plaque index was obtained, probing depth was stable, and gingival thickness and margin stability had increased. Complications (biological and mechanical) did not present a statistically significant incidence and a crown survival rate of 97.2% was achieved. Patients’ satisfaction obtained a mean VAS score of 9.04 under 10. Conclusion. Teeth that are prepared with BOPT in the anterior region present good periodontal behavior around the restored teeth, particularly in terms of the stability of the gingival margin and increased gingival thickness. Single crowns prepared with BOPT obtain an excellent clinical survival rate, as well as a high score in patients’ satisfaction after 6 years.

Statement of problem One of the most frequent complications in participants with fixed partial dentures (FPDs) is the apical migration of the gingival margin, which may be associated with factors such as fit, gingival margin location, or tooth preparation type. The prevalence of the complication in participants restored with FPDs prepared by using the biologically oriented preparation technique (BOPT) is unclear. Purpose The purpose of this prospective clinical trial was to evaluate the clinical and biologic outcomes of FPDs on teeth prepared by using the BOPT, over a 6-year follow-up period. Material and methods Tooth-supported zirconia FPDs in the anterior region prepared by using the BOPT were evaluated. Each participant was monitored annually for 6 years by evaluating plaque index, probing depth, vestibular gingival thickness, and gingival margin stability. Biologic and/or mechanical complications were also recorded. Patient satisfaction was measured by using a visual analog scale (VAS). Results A total of 25 FPDs supported by 70 teeth in 24 participants were analyzed. Low plaque index values and stable probing depths were observed, whereas the gingival index was 0 for most of the teeth. Teeth treated by using the BOPT presented significant increase in gingival thickness, and the gingival margin was found to be stable in 100% of the treatments. FPD survival was 100%. Conclusion Tooth supporting FPDs prepared by using the BOPT presented good periodontal health and gingival margin stability, without recession and with a 100% survival rate during a 6-year follow-up.

Background and Objectives: To evaluate in vitro the fracture resistance and fracture type of computer-aided design and computer-aided manufacturing (CAD-CAM) materials. Materials and Methods: Discs were fabricated (10 &times, 1.5 mm) from four test groups (N = 80, N = 20 per group): lithium disilicate (LDS) group (control group): IPS e.max CAD&reg, zirconium-reinforced lithium silicate (ZRLS) group: VITA SUPRINITY&reg, polymer-infiltrated ceramic networks (PICN) group: VITA ENAMIC&reg, resin nanoceramics (RNC) group: LAVA&trade, ULTIMATE. Each disc was cemented (following the manufacturers&rsquo, instructions) onto previously prepared molar dentin. Samples underwent until fracture using a Shimadzu&reg, test machine. The stress suffered by each material was calculated with the Hertzian model, and its behavior was analyzed using the Weibull modulus. Data were analyzed with ANOVA parametric statistical tests. Results: The LDS group obtained higher fracture resistance (4588.6 MPa), followed by the ZRLS group (4476.3 MPa) and PICN group (4014.2 MPa) without statistically significant differences (p &lt, 0.05). Hybrid materials presented lower strength than ceramic materials, the RNC group obtaining the lowest values (3110 MPa) with significant difference (p &lt, 0.001). Groups PICN and RNC showed greater occlusal wear on the restoration surface prior to star-shaped fracture on the surface, while other materials presented radial fracture patterns. Conclusion: The strength of CAD-CAM materials depended on their composition, lithium disilicate being stronger than hybrid materials.

Background: Calculus accumulation varies widely between individuals. Dental calculus has been associated with the principal periodontal diseases. The aim of this study was to analyze individual characteristics, and salivary and microbiological parameters among patients considered to be rapid calculus formers and patients who form calculus slowly. Methods: Individual characteristics were recorded in a sample of 74 patients (age, sex, smoking, periodontal diagnosis, and dental crowding), as well as salivary parameters (unstimulated saliva flow, pH, and biochemical analysis of saliva) and microbiological parameters (by means of semi-quantitative polymerase chain reaction (PCR) analysis). Results: A statistically significant association (p = 0.002) was found between the rate of calculus formation and the diagnosis of periodontal disease. A greater presence of dental crowding was observed among the group of rapid calculus formers. Urea and phosphorus levels were higher among rapid calculus formers. Regarding microbiological parameters, differences were found in Streptococcus mutans, this being higher in the group of slow formers. Conclusions: Rapid calculus formation appears to be linked to patients diagnosed with more severe periodontal diseases. Rapid calculus-forming patients present more dental crowding and a lower proportion of S. mutans.

Background The aim of this systematic review was to analyze the types of human chewing simulator described in scientific literature. Material and Methods An electronic search was conducted in the databases PubMed, Embase and Scopus. The search strategy included 10 search terms: “in vitro”; “dental materials”; “shear strength”; “fatigue fracture”; “bite force”; “prosthetic materials”; “chewing simulator”; “chewing machine”; “simulated mastication”; and “dental wear simulator.” Two researchers worked independently to assess the titles and abstracts of the articles. The quality of the in vitro trials selected was evaluated by means of the Consolidated Standards of Reporting Trials scale. Results The electronic search identified 80 articles related to the topic of interest. After reading the full texts, ten works were selected. The articles focused mainly on the design of chewing simulators. Most of them were considered of moderate quality. Regarding the characteristics that an ideal chewing simulator should encompass, the devices described in articles varied greatly in terms of movement, periodontal ligament simulation, force sensors, and the materials tested. Conclusions No chewing simulator offers all the characteristics necessary to reproduce human masticatory movements and forces under the humidity and pH conditions of the oral cavity. A simulator that encompasses all these characteristics would make it possible to standardize trials involving simulated mastication. Key words:In vitro, dental materials, dental wear simulator.

Background The aim of this study was to conduct histological analysis of a human tooth resected with the periodontal insertion apparatus intact following treatment using biologically oriented preparation technique (BOPT). Material and methods This descriptive histological dento-periodontal study used an anterior tooth extracted with the surrounding periodontal tissues intact, following prosthetic restoration with BOPT. The sample patient was recruited from among those attending the Department of Dental Medicine at the Faculty of Medicine and Dentistry, University of Valencia (Spain). Eight serial sections of the restored tooth were processed. The relative location and histological characteristics of the cemented prosthetic crown, the dental tissues of the tooth prepared by BOPT technique, and the periodontal tissues were analyzed. Results Structural analysis of the neoformed junctional epithelium showed that the number of layers decrease apically until there was a single row of cells perfectly adhered to the acellular cementum, and beneath the epithelium a connective tissue evidently free from inflammation. The tissues of the neoformed periodontium (gingival ligament, sulcular epithelium, junctional epithelium) presented histologic normality. Conclusions Biologically oriented preparation technique is a reliable alternative to conventional horizontal finish lines. Key words:Vertical preparation, prosthetic cementoenamel junction (PCEJ), finish line, BOPT, crown.

Purpose: The objective of this prospective randomized clinical trial (RCT) was to analyze and compare the clinical behavior of three types of prosthesis supported by single implants in the posterior region after three years of functional loading. Materials and methods: Seventy-five implants were divided into three groups according to the type of prosthetic restoration: screw-retained crown (group GS); cemented crown without finishing line (biologically oriented preparation technique) (group GBOPT); and conventional cemented crown with finishing line (group GCC). After three years in function, clinical parameters (presence of keratinized mucosa, probing depths, bleeding on probing, and radiographic bone loss) were compared between the three experimental groups. The possible correlation between soft tissue clinical parameters and bone loss was also analyzed. Results: Statistical analysis found significant differences in clinical parameters between the different types of crown, with the cemented restoration without finishing line (BOPT) presenting fewer complications and better peri-implant health outcomes including: significantly different KMW data (mm), with significant differences between groups GBOPT and GCC (p < 0.001, Kruskal–Wallis test), with GBOPT obtaining larger quantities of keratinized mucosa (KM); statistically significant differences in probing depth (PD) values between groups GBOPT and GCC (p = 0.010, Kruskal–Wallis test); significant differences in bleeding on probing (BOP) between groups GBOPT and GCC (p = 0.018, Chi2 test) in favor of GBOPT. Conclusions: Soft tissue behavior around implants is related to the type of prosthetic restoration used, with cemented prostheses with BOPT presenting better peri-implant soft tissue behavior.

Purpose: The objective of this prospective randomized clinical trial (RCT) was to analyze and compare the clinical behavior of three types of prosthesis supported by single implants in the posterior region after three years functional loading. Materials and Methods: Seventy-five implants were divided into three groups according to the type of prosthetic restoration: screw-retained crown (Group GS); cemented crown without finishing line (biologically oriented preparation technique) (Group GBOPT); and conventional cemented crown with finishing line (Group GCC). The clinical behavior of each restoration type was analyzed after 3 years functional loading by analyzing radiographic peri-implant bone loss. Results: GBOPT obtained the least bone loss (p < 0.01) in comparison with GS and GCC. Conclusions: Bone loss around implants is related to the type of prosthetic restoration it supports, whereby cemented BOPT crowns present less bone loss.

Background: The aim of this systematic review and meta-analysis was to determine the fracture resistance and survival rate of partial indirect restorations inlays, onlays, and overlays fabricated using computer-aided design and computer-aided manufacturing (CAD-CAM) technology from ceramics, composite resin, resin nanoceramic, or hybrid ceramic and to analyze the influence of proximal box elevation on fracture resistance. Materials and methods: This systematic review was based on guidelines proposed by the preferred reporting items for systematic reviews and meta-analyses (PRISMA). An electronic search was conducted in databases US National Library of Medicine National Institutes of Health (PubMed), Scopus, Web of Science (WOS), and Embase. In vitro trials published during the last 10 years were included in the review. Results: Applying inclusion criteria based on the review’s population, intervention, comparison, outcome (PICO) question, 13 articles were selected. Meta-analysis by restoration type estimated the fracture resistance of inlays to be 1923.45 Newtons (N); of onlays 1644 N and of overlays 1383.6 N. Meta-analysis by restoration material obtained an estimated fracture resistance for ceramic of 1529.5 N, for composite resin of 1600 Ne, for resin nanoceramic 2478.7 N, and hybrid ceramic 2108 N. Conclusions: Resin nanoceramic inlays present significantly higher fracture resistance values. Proximal box elevation does not exert any influence on the fracture resistance of indirect restorations.

Purpose: To analyze in vitro the mechanical behavior of five types of complete coverage crowns fabricated from different materials. Materials and methods: Seventy-five full coverage crowns were divided into five groups according to material: Group I, metal core with feldspathic ceramic covering (MC- control group), Group II, zirconia core with feldspathic ceramic covering (CZ), Group III, tetragonal monolithic zirconia (TMZ), Group IV, cubic monolithic zirconia (CMZ), Group V, high molecular weight polymethyl methacrylate (PMMAG) doped with graphene nanoparticles. All crowns underwent in vitro fatiguing by dynamic loading in wet conditions to simulate the masticatory forces to which prosthodontic materials are subject in the oral medium. Lastly, fracture resistance was evaluated by static compression testing. Results: The fracture resistance values obtained were as follows: Group MC, 2443.6 &plusmn, 238.6 N, Group CZ, 2095.4 &plusmn, 329.2 N, Group TMZ, 2494.6 &plusmn, 236.6 N, Group CMZ, 1523.6 &plusmn, 325.2 N, and Group PMMAG, 1708.9 &plusmn, 386.6 N. Group MC presented higher strength with statistically significant differences in comparison with Groups CZ (P = 0.002), CMZ (P &lt, 0.001), and PMMAG (P &lt, 0.001). Weibull distribution showed less probability of cumulative biomechanical failure in Groups MC and TMZ. Conclusions: Metal-ceramic and tetragonal zirconia showed high fracture resistance, while cubic zirconia and PMMA doped with graphene nanoparticles obtained lower values.

Background This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth. Material and Methods This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophosphate-based test mouth rinse (B) or a placebo (A). A range of parameters were measured for: saliva (saliva flow, pH and chemical composition); calculus (Volpe-Manhold [V-M] index, weight, and volume); adverse effects on mucosa and teeth; and the patients’ subjective perceptive of mouth rinse efficacy. Results The test mouth rinse B produced reductions in urea, uric acid, and phosphorous, calcium, saliva flow, and increases in pH. V-M index and calculus weight decreased after using the test mouth rinse. Calculus volume decreased with both mouth rinses. No changes to the mucosa or teeth were observed. Patients perceived that the test mouth rinse was more effective. Conclusions The test/B and placebo mouth rinses both modified certain parameters in saliva composition, particularly reductions in urea, uric acid, and phosphorous. Calcium tended to increase after using the test-B mouth rinse. The results did not demonstrate the anticalculus efficacy of the pyrophosphate-based mouth rinse or positive effects on saliva flow or composition. This field requires further research, as no product has been developed that prevents calculus formation completely. Key words:Dental calculus, anticalculus mouth rinse, Volpe Manhold index.

Background As there is no standard method for re-cementing debonded partial ceramic restorations, the aim of this study was to evaluate the use of a non-invasive thermal protocol for cleaning and retreatment, and to study its influence on shear bond strength. Material and methods Twenty ceramic samples (IPS e.max CAD®) were bonded to composite cement cylinders and underwent a shear bond strength test (G1, n=20). A second group was created (G2, n=20), representing debonded restorations. To simulate debonding, the samples were artificially contaminated with composite cement. After debonding, these underwent a thermal protocol to remove remaining adhesive. After rebonding to the composite cement cylinders, samples underwent the shear bond strength test. Results Median bond strengths for G1 and G2 were 7.28±3.23; 7.06±3.41 MPa, respectively, without significant difference between the groups (p=0.983). Conclusions Debonded lithium disilicate glass-ceramic restorations should undergo a laboratory cleaning and retreatment protocol before being returned to the clinic for rebonding. Key words:Ceramic, adhesive debonding, shear bond strength, porcelain laminated veneers.

The purpose of the investigation was to analyze fracture resistance and mode of failure of zirconium oxide (zirconia) abutments placed on dental implants bearing crowns of different esthetic materials: zirconia, lithium disilicate (LDS), and nano-ceramic resin, for replacing single teeth in the anterior sector. Eighty implant-abutment-crown units were divided into four groups: Group T-MC (control): 20 metal-ceramic crowns cemented onto titanium abutments; Group Z-Z: 20 zirconia crowns on zirconia abutments; Group Z-LD: 20 lithium disilicate crowns on zirconia abutments; and Group Z-NCR: 20 nano-ceramic resin crowns on zirconia abutments. Specimens underwent a fatiguing process (dynamic loading and thermocycling), followed by static loading to evaluate mechanical fracture resistance, and the mode of failure produced. Mean fracture resistance values were: Control Group T-MC, 575.85±120.01 N; Group Z-Z 459.64±66.52 N; Group Z-LD, 531.77±34.10 N; and Group Z-NCR, 587.05±59.27 N. In Group T-MC, fracture occurred in the prosthetic fixing screw in 100% of specimens. In Group Z-Z, 80% of fractures occurred in the fixing screw, 15% in the abutment, and 5% in the abutment and crown. In Group Z-LD, 60% of fractures were produced in the fixing screw and 40% in the abutment. In Group Z-NCR, 70% of fractures were produced in the fixing screw and 30% in the abutment. All the abutments and crowns analyzed have the potential to withstand the physiological occlusal forces to which they would be subject in the anterior region. Lithium disilicate and nano-ceramic resin crowns cemented onto zirconia abutments are a good restoration alternative for single implants in the anterior sector.

Purpose The aim of this study was to evaluate the mechanical behavior of implant-supported cemented restorations placed on two types of abutment design, with and without a prosthetic finish line, evaluating fracture resistance and the type of fracture produced in the abutment-crown complex. Materials and methods Eighty zirconia restorations supported by tapered implants were divided into two groups: group I, with 40 zirconia crowns cemented onto individualized zirconia abutments with a chamfered finish line (1 mm deep); and group II, with 40 zirconia crowns cemented onto individualized zirconia abutments without a finish line. All specimens underwent thermocycling and dynamic loading before static load testing to evaluate their fracture resistance. Results Fracture resistance values (N) and the type of fracture were analyzed. The mean fracture resistance was 462.1 ± 66.3 N in group I and 343 ± 40 N in group II. In group I, fractures were produced in the prosthetic fixation screw; in group II, all mechanical failures were produced in the transepithelial abutment's cervical area. Conclusion Group I specimens showed greater fracture resistance than group II. The fracture type in group I occurred in the prosthetic screw. Group II fractures occurred in the zirconium oxide abutment.

This study aimed to determine the effectiveness of a mandibular advancement device in a sample of obstructive sleep apnea syndrome patients by the evaluation of respiratory and neurophysiologic parameters and clinical symptoms. Second, the influence of certain predictor factors related with the patient and the intraoral device, were considered in the final response with this treatment option. Forty-one patients constituted the final sample. Outcomes were measured using polysomnography, Epworth sleepiness scale and an analogue visual snoring scale, before treatment and once the device was properly titrated. Mean apnea–hypopnea index decreased from 22.5 ± 16.8 to 9.1 ± 11.6 (p ≤ 0.05), influencing only gender and Fujita index as predictor factors. The oxygen saturation, arousal index, percentages of sleep stages and sleep efficiency significantly improved with the mandibular advancement device (MAD) placement. The snoring index improved in absolute terms in 6.1 units and the excessive daytime sleepiness was reduced from 12.2 ± 4.7 to 8.5 ± 3.8 (p ≤ 0.00). The successful treatment rate with the MAD was 65.8%. The placement and posterior regulation of the intraoral appliance efficiently reduced the apnea–hypopnea index, improved the sleep quality and the clinical symptomatology associated. Obstructive sleep apnea syndrome is a highly prevalent disease. and dentists should be aware of the benefits enhanced by this prosthetic device, considered the first treatment option by certain physicians.

BACKGROUND: When partial coverage restorations (veneers, inlays, onlays…) must be cemented to dentin, bond strength may not reach the same predictable values as to enamel. The purpose of this study was: 1. To compare, with a shear bond test, the bond strength to dentin of a total-etch and a self-etching bonding agent. 2. To determine whether creating microretention improves the bond strength to dentin. MATERIAL AND METHODS: Two bonding agents were assayed, Optibond FL® (Kerr), two-bottle adhesive requiring acid etching, and Clearfil SE Bond® (Kuraray), two-bottle self-etching adhesive. The vestibular, lingual, distal and mesial surfaces of ten molars (n=10) were ground to remove all enamel and 40 ceramic samples were cemented with Variolink II® (Ivoclar Vivadent). Half the molar surfaces were treated to create round microretention (pits) to determine whether these could influence bond strength to dentin. The 40 molar surfaces were divided into four groups (n=10): Optibond FL (O); Clearfil SE (C); Optibond FL + microretention (OM); Clearfil SE + micro retention (CM). A shear bond test was performed and the bond failures provoked examined under an optical microscope. RESULTS: O=35.27±8.02 MPa; C=36.23±11.23 MPa; OM=28.61±6.27 MPa; CM=27.01±7.57 MPa. No statistically significant differences were found between the adhesives. Optibond FL showed less statistical dispersion than Clearfil SE. The presence of microretentions reduced bond strength values regardless of the adhesive used. CONCLUSIONS: 1. Clearfil SE self-etching adhesive and Optibond FL acid-etch showed adequate bond strengths and can be recommended for bonding ceramic restorations to dentin. 2. The creation of round microretention pits compromises these adhesives' bond strength to dentin. Key words:Adhesion to dentin, bonding agent, Optibond FL, Clearfil SE, microretention, shear bond test.

The rehabilitation of the atrophic maxilla by means of implant-supported prostheses cannot always be achieved with fixed prostheses because of anatomic, esthetic, or economic issues, so for some patients the treatment of choice is a removable prosthesis. This article analyzes a new design for implant-supported overdentures with horizontal or faciolingual insertion. Its retention system is based on frictional forces or stepped interlocking horizontal surfaces and is appropriate for patients with skeletal Class II or III relationships with severe maxillary atrophies. The design facilitates implant-prosthetic hygiene and improved esthetics in patients with nonparallel implants by hiding abutment screws.

Objectives: This study aims to determine whether bruxism and the use of occlusal splints affect the survival of porcelain laminate veneers in patients treated with this technique. Material and Methods: Restorations were made in 70 patients, including 30 patients with some type of parafunc - tional habit. A total of 323 veneers were placed, 170 in patients with bruxism activity, and the remaining 153 in patients without it. A clinical examination determined the presence or absence of ceramic failure (cracks, frac - tures and debonding) of the restorations; these incidents were analyzed for association with bruxism and the use of splints. Results: Analysis of the ceramic failures showed that of the 13 fractures and 29 debonding that were present in our study, 8 fractures and 22 debonding were related to the presence of bruxism. Conclusions: Porcelain laminate veneers are a predictable treatment option that provides excellent results, rec - ognizing a higher risk of failure in patients with bruxism activity. The use of occlusal splints reduces the risk of fractures.

Background Classic self-curing temporary cements obstruct the translucence of provisional restorations. New dual-cure esthetic temporary cements need investigation and comparison with classic cements to ensure that they are equally retentive and provide adequate translucence. The objective is to analyze by means of traction testing in a in vitro study the retention of five temporary cements. Material and methods Ten molars were prepared and ten provisional resin restorations were fabricated using CAD-CAM technology (n=10). Five temporary cements were selected: self-curing temporary cements, Dycal (D), Temp Bond (TB), Temp Bond Non Eugenol (TBNE); dual-curing esthetic cements Temp Bond Clear (TBC) and Telio CS link (TE). Each sample underwent traction testing, both with thermocycling (190 cycles at 5-55o) and without thermocycling. Results TE and TBC obtained the highest traction resistance values. Thermocycling reduced the resistance of all cements except TBC. Conclusions The dual-cure esthetic cements tested provided optimum outcomes for bonding provisional restorations. Key words:Temporary dental cements, cements resistance.

Background Silicate ceramic bonding is carried out by acid-etching with hydrofluoric acid (HF) followed by an application of silane. By replacing HF with ammonium polyfluoride, contained in the same flask as the silane, the number of steps in this clinical procedure, can be reduced, while maintaining bond strength values, and reducing toxicity. A shear bond test was performed to compare the conventional and the simplified surface treatment techniques. Material and methods Twenty ceramic samples were fabricated from IPS emax CAD® ceramic (Ivoclar Vivadent) and divided into two groups (G1 and G2) (n=10). The conventional technique was applied to G1 samples, and the simplified technique to G2 samples. A resin cement cylinder was bonded to each sample. Afterwards, samples underwent shear bond strength testing in a universal test machine. Results G1 obtained 26.53±6.33 MPa and G2 23.52±8.41 MPa, without statistically significant differences between the two groups. Conclusions Monobond Etch&Prime appears to obtain equivalent results in terms of bond strength while simplifying the technique. Further investigation is required to corroborate these preliminary findings. Key words:Shear bond strength, surface treatment, bonding to ceramic, hydrofluoric acid, ammonium polyfluoride.

An intraoral digital scanner in combination with specialized three-dimensional surface analysis software monitors volumetric changes to soft tissues or dental restorations. This technology can evaluate the success of a specific technique or medium- or long-term clinical outcomes in both clinical and research situations. This article describes how this technology was used to provide immediate chair-side data analysis without the help of specialized laboratory support. Key words:Intraoral scanner, CAD-CAM, best fit-method, surface tessellation language.

Background Specimen preparation for in vitro study suffers a general lack of methodological homogeneity, as well as a lack of uniformity in the materials selected for fabricating them. This situation prevents comparisons between studies. When a specimen is not of dental origin it is not possible to study adhesion or bonding techniques realistically. The objective is to design and implement a method of specimen preparation that permits universal standardization for use in in vitro studies. Material and Methods A metal stump of specified dimensions was designed and fabricated by hand. It was scanned, the data digitalized, perfecting and standardizing the dimensions. Ten human molars were adapted to the size and shape of a standard milling block. A Cerec 3D inLab Cerec milling unit was used to prepare the molars to match the digitalized model. Results Ten specimens with identical dimensions were obtained. Conclusions CAD-CAM technology allows the preparation of natural extracted teeth to be standardized and could be used to establish a reproducible method that would facilitate comparison between different in vitro studies, and reduce bias arising from variations in sample fabrication. Key words:Test ceramic, dentin analog, dentin model, dentin samples, methodology.

Objectives: The aim of this article is to propose a resin cement cleaning protocol for use before recementing a debonded restoration. Study Design: Ceramic samples were fabricated from IPS d.sign® and IPS e.max Press® and were treated with hydrofluoric acid etching (HF), or HF+silane (S), or HF+S+adhesive or HF+S+A+resin cement. All samples were placed in a furnace at 650º for one minute in order to attempt to pyrolyze the composite. Each step was examined under scanning electron microscopy (SEM). Results: When the cleaning protocol had been performed, it left a clean and retentive surface. Conclusions: If the restoration is placed in a furnace at 650º for one minute, the composite cement will burn or pyrolyze and disappear, allowing conventional retreatment of the ceramic before rebonding. Key words:Ceramic, debond, surface treatment.

Objective: The objective of this study was to evaluate the clinical results of 323 porcelain laminate veneers over a period of 3 to 11 years. Material and Methods: This study included 70 patients, aged between 18 and 74 years. Of the 323 total veneers, 124 were of a simple design and 199 were of a functional design. The condition of the soft tissues and hygiene, in addition to the condition of the abutment teeth, the restorations and patient satisfaction were all clinically examined. In carrying out the statistical analysis, a descriptive approach was taken in analyzing the data. The Kaplan Meier method was used for statistically analyzing the survival rates of the porcelain laminate veneers. Results: Analysis of the soft tissue revealed marginal recession in 7.7% of the cases, and in 21.6% of the cases, bleeding was detected on probing. Analysis of the condition of the abutment teeth revealed secondary caries and hypersensitivity in 3.1% of the cases, and changes in pulp vitality were observed in 2.8% of the cases. In studying the condition of the restorations, marginal integrity was observed to be excellent in 98% of the cases, slight marginal pigmentation was present in 39.3% of the cases, fractures were present in 4% of the cases and decementation in 9% of the cases. The degree of patient satisfaction was considered to be excellent in 97.1% of the cases. Conclusions: Porcelain laminate veneers are a predicable treatment option that offer excellent results.

To evaluate bond strengths of different resin cements to two aluminum oxide-based ceramics. Methods: One hundred ten ceramic cylinders were produced and given four different surface treatments. Resin cement cylinders were then bonded to the ceramic cylinders using different resin cements and the bond strength was determined by shear testing to the breaking point. We were thus able to obtain results for the different combinations of porcelain, surface treatments and cements. All data was analyzed using the Kruskal-Wallis test for more than two independent samples and the Bonferroni correction applied (a=0.01). An optical microscopy study was carried out to analyze the type of failure, and an electronic microscopy examination was carried out in order to evaluate the changes produced in the ceramic by the different surface treatments. Results: The best values corresponded to the control group, composed of silicate ceramics combined with Variolink II resin cement. In-Ceram Alumina showed no significant differences with respect to the type of cement applied. Procera AllCeram obtained the best values when silica coated using the CoJet System and applying Variolink II, or when sandblasted and applying Clearfil SE Bond + Porcelain Bond Activator and Panavia F cement. Significance: Surface treatment modifies the ceramic surface and influences the bond strength, as does the type of cement used. Silica coating is recommended to improve adhesion to Procera AllCeram, applying Variolink II, or sandblasting plus resin cement containing MDP (Panavia F)

Introduction: Implant-supported prostheses have to overcome a major difficulty presented by the morphology and esthetics of peri-implant tissues in the anterior sector. Diverse therapeutic techniques are used for managing the mucosa adjacent to the implant and the most noteworthy is immediate/deferred fixed provisionalization. Objectives: In vitro testing of strength and deformation of implant prosthetic abutments made from different materials (Titanium/PEEK/methacrylate). Material and Methods: Forty Sweden&Martina® implant prosthetic abutments (n=40) were divided into five groups: Group MP: methacrylate provisional abutments with machined titanium base; Group PP: Poly ether ether ketone (PEEK) provisional abutments; Group TP: titanium provisional abutments; Group TAD: titanium anti-rotational definitive abutments; Group TRD: titanium rotational definitive abutments. Their mechanical behavior under static loading was analyzed. Samples were examined under a microscope to determine the type of fracture produced. Results and Conclusions: Definitive anti-rotational titanium abutments and definitive rotational titanium abutments achieved the best mean compression strength, while PEEK resin provisional abutments obtained the lowest. The group that showed the greatest elastic deformation was the group of titanium provisional abutments. Key words:Immediate loading, immediate provisionalization, implant prosthetic abutment, definitive implant prosthetic abutment.

The purpose of the present study is to evaluate the fracture load of composite-based repairs to fractured zirconium oxide (Z) crowns and to ceramic-fused-to-metal (CM) crowns, comparing different mechanical surface preparation methods. A total of 75 crowns were repaired; samples then underwent dynamic loading and thermocycling. Final fracture load values for failure of the repaired crowns were measured and the type of fracture registered. Group I: CM: Surface preparation with a diamond bur + 9.5% Hydrofluoric Acid (HF) etching; Group II): CM: air-particle (Al 2 O 3 ) + 9.5% HF; Group III: CM: Silica coating (SiO 2 ); Group IV): Z: air-particle (Al 2 O 3 ) + HF 9.5%; Group V) Z: Silica coating (SiO 2 ). Of the three CM groups, Group I (CM-diamond bur) showed the highest mean failure value, with significant difference in comparison with Group III (CM-silica coating). For the zirconia groups, the highest value was obtained by Group V (silica coating).

Early restoration of the masticatory function, phonatory and aesthetics is some of the current goals of the therapy based on endosseous implants. Facing the classic protocols of implant insertion, which recommend a period of several months between extraction and implant placement, alternatives have been developed that demonstrate that immediate implant placement after tooth extraction permits adequate osseointegration, even in those cases where there is a periapical disease. The immediate restoration of implants after placement is a possibility where aesthetic requirements are high. This article presents a case with immediate implant placement and immediate loading of a first upper premolar with prior periapical pathology due to a vertical fracture. The immediate prosthetic was performed using the extracted crown, which is adapted to be attached to a titanium temporary abutment using a resin cement. After a 4 month healing period work began on the final prosthetic crown. The screw crown was made of zirconium oxide with a covering feldspathic ceramic. At the 12-month follow-up, there were no mechanical or biological complications. The patient gave high satisfaction marks for the overall treatment, giving visual analogue scale score of nine. Immediate post-extraction implants have arisen as an alternative to traditional implants on completely healed bone. Their main aim is to reduce treatment time and number of surgical procedures, along with other objectives such as reduced bone re-absorption and improved aesthetics. Key words:Post-extraction implants, immediate loading prosthetic, implant-retained prosthesis, periapical disease, vertical fracture.

Purpose: The purpose of this study was to compare the differences in surface characteristics and roughness of teeth finished for porcelain veneer laminates using different instrumentation and to assess their influence on microleakage. Materials and Methods: Fifty-six extracted human maxillary central incisors were divided randomly into two groups: Group HsR teeth were finished with a high-speed handpiece with diamond burs; group SO teeth were finished with a sonic oscillating diamond instrument. Porcelain veneers were bonded to 24 teeth in each group. Microleakage was measured in the cervical area. Four remaining teeth in each group were examined using confocal laser-scanning microscopy and scanning electron microscopy. Results: Oscillating instruments produced a rougher dentinal surface (Ra values; P = .029) than those finished with high-speed rotary technology. Conclusions: There is less microleakage when bonded restoration edges are situated over dentin that has been finished with sonic oscillating instrumentation (P = .006).

Statement of problem Because of the high mechanical strength of zirconium dioxide, the metal in fixed partial prostheses can now be replaced. However, the material is susceptible to aging or hydrothermal degradation and to chipping of the feldspathic veneer. Purpose The purpose of this prospective study was to evaluate the survival (without failure) and success (survival without any complication or failure) rate and clinical efficacy of anterior zirconia partial fixed dental prostheses. Material and methods Twenty-seven anterior partial fixed dental prostheses of 3 to 6 units were fabricated. All participants were examined after 1 month and 6 months, then annually for 7 years. Results Three partial fixed dental prostheses failed and had to be removed: 2 because of secondary caries, which increased failure significantly ( P =.001) and 1 because of severe chipping. Six partial fixed dental prostheses had complications: 2 debonded, 3 had chipping, and 1 had periapical pathology. All veneer porcelain fractures occurred in 6-unit fixed partial prostheses ( P =.002). The clinical success rate was 88.8% after the 7-year follow-up. Conclusions The clinical behavior of partial fixed dental prostheses with a zirconium dioxide core in the anterior region provides an adequate medium-term survival rate. The main cause of failure was secondary caries. The most frequent complication was chipping, which was directly related to the number of units of the prosthesis.

With the appearance of all-ceramic systems, providing a choice of framework porcelains and allowing the same material to be used for the veneer, it is now possible to select the ideal structure in terms of both function and esthetics. Silicate ceramics allow porcelain laminate veneers and crowns to be used in the anterior region, providing excellent esthetics; while for the posterior area, where function takes precedence, oxide ceramics, specifically zirconium oxide, are preferred. The IPS e.max ceramic system, heir apparent to the IPS Empress 2 system, combines the advantages of zirconium oxide ceramics (IPS e.max Zircad) with the excellent esthetic qualities of silicate ceramics (IPS e.max Press). This paper presents a clinical case requiring complete maxillary rehabilitation for esthetic purposes. An overview of some of the porcelains used in this system, analyzed from both the clinical and laboratory perspective is provided. The esthetic advantages of a single ceramic veneer, the need to select appropriate ceramics for anterior and posterior regions, and cementation and surface treatments are discussed.

Purpose The aim of this prospective study was to evaluate the clinical efficacy and long-term survival rate of three-unit fixed partial dentures (FPDs) made from lithium disilicate-based core ceramic. Materials and methods Twenty-one three-unit FPDs were placed in 19 patients to replace single lost teeth in the esthetic area, following a study protocol that took clinical, esthetic, and radiologic aspects into consideration. Each case was reviewed at 1 week following placement, at 6 months, and then annually for 10 years. Statistical analysis was performed using Kaplan-Meier survival analysis. Results Out of the 19 patients, 14.3% presented reversible postoperative sensitivity. Recession was observed in 24% of dental posts, and 7.1% presented marginal discoloration. Treatment did not increase either Bleeding or Plaque Index scores at prepared teeth; secondary caries did not appear either. The restorations' survival rate at the 10-year follow-up was 71.4%; six FPDs had fractured and one debonded. Conclusions Fracture failure rate was 28.6% after 10 years; a high percentage corresponded to connector fractures and occurred during the first 5 years. Lithium disilicate glass-ceramic FPDs present a higher risk of fracture than standard therapies (metal-ceramic) or other more recently developed ceramic materials. The prognosis for survival improves for Class I occlusion and nonparafunctional patients.

Objectives: The aim of this study was to evaluate bond strengths of zirconium-oxide (zirconia) ceramic and a selection of different composite resin cements. Study Design: 130 Lava TM cylinders were fabricated. The cylinders were sandblasted with 80 μm aluminium oxide or silica coated with CoJet Sand. Silane, and bonding agent and/or Clearfil Ceramic Primer were applied. One hundred thirty composite cement cylinders, comprising two dual-polymerizing (Variolink II and Panavia F) and two autopolymerizing (Rely X and Multilink) resins were bonded to the ceramic samples. A shear test was conducted, followed by an optical microscopy study to identify the location and type of failure, an electron microscopy study (SEM and TEM) and statistical analysis using the Kruskal-Wallis test for more than two independent samples and Mann-Whitney for two independent samples. Given the large number of combinations, Bonferroni correction was applied (α=0.001). Results: Dual-polymerizing cements provided better adhesion values (11.7 MPa) than the autopolymerizing (7.47 MPa) (p-value M-W, The authors acknowledge the support of the 'Microcluster de Biomateriales Odontologicos' of the VLC/CAMPUS Valencia International Campus of Excellence.

Clinical studies have revealed a high rate of fracture for porcelain-veneered zirconia-based restorations that varies between 6% and 15% over a 3- to 5-year period. These are high values compared to the 4% fracture rate shown by conventional metal-ceramic restorations over 10 years. To date, little in vitro research has been carried out on the fracture resistance of the new generation of ceramic crowns. The aims of this study were to develop preliminary research on the mechanical failure behavior of three types of porcelain-veneered crowns with zirconia cores when subjected to static compressive loading and to analyze fracture characteristics using scanning electron microscopy (SEM).Eighty individual full-coverage crowns were studied: 60 crowns with a zirconia core and 20 with a metal core (control).Values obtained in compressive testing were as follows: ZirPress: 1,818.01 N, ZirCAD: 1,773.92 N, Lava: 2,210.95 N, and metal-ceramic (control): 2,310.49 N. SEM analysis revealed that 71.66% of zirconia-based restoration mechanical failures were cohesive, while 100% of mechanical failures for metal-ceramic restorations were adhesive.The mechanical behavior of the porcelain veneering on a zirconia core is more fragile than that on metal-ceramic crowns, and when load forces exerted on these restorations lead to mechanical failure, this will occur in the interior of the porcelain veneering.

Objective: To define the clinical and radiological characteristics of the four most common presentations of temporomandibular dysfunction-myofascial pain (MFP), disc displacement with reduction (DDWR), disc displacement without reduction (DDWoR), and osteoarthrosis (OR)-and to identify the differences among them. Material and methods: The study comprised a series of 850 patients (121 males and 729 females) seen between May 2003 and December 2006 in Valencia University General Hospital (Spain) for temporomandibular joint disease (TMJD). An analysis was made of the possible etiological factors (stress, traumatisms, sleep disturbances, parafunctional habits, reason for consultation), possible pain sensations in response to palpation of the masticatory muscles, joint sounds, etc. A panoramic X-ray study was made on a routine basis, and in some patients (n = 54) the study was completed with a magnetic resonance imaging scan of the temporomandibular joints and related tissues. The differences between qualitative variables were examined by means of the chi-square test with R x C contingency tables and the Z-test, while quantitative variables were contrasted by analysis of variance (ANOVA) and post hoc testing (Scheffe). Results: The variables showing statistically significant differences among the four diagnostic categories were: patient age, sleep disturbances, stress, parafunctional habits, nibbling on hard objects and ?parafunctions?, reason for consultation, mandibular movements, ?non-evaluable? molar and canine relationship, ligament hyperlaxity, and panoramic X-ray alterations.

Porcelain laminate veneers (PLVs) have been used for over two decades to treat esthetic and/or functional problems, particularly in the anterior sector. A range of dental ceramic materials are presently available on the market for these treatments, though with very different characteristics in terms of the composition, optic properties and manufacturing processes involved. As a result, selection of the material best suited for the management of each individual patient may prove complicated. The present study proposes a simple system for selecting the most appropriate ceramic material, based on the two variables that most influence the esthetic outcome: the intrinsic characteristics of the substrate tooth, and the characteristics of the ceramic material in terms of resistance and optic properties.