1. Cutaneous infection in an immunocompromised domestic cat caused by Setosphaeria turcica (Luttr.) Leonard & Suggs.
- Author
-
Antonelo FA, Soares Rodrigues M, Kraus TJ, Souza da Silva M, and Fernandes Montanher P
- Subjects
- Animals, Cats, Ascomycota isolation & purification, Itraconazole therapeutic use, Antifungal Agents therapeutic use, Male, Dermatomycoses veterinary, Dermatomycoses microbiology, Dermatomycoses drug therapy, Cat Diseases microbiology, Cat Diseases drug therapy, Immunocompromised Host
- Abstract
This is the first report of a cutaneous infection in an immunocompromised domestic cat caused by Setosphaeria turcica. The investigation encompasses an assessment of its virulence factors and susceptibility to antifungal drugs. The isolated strain originated from a domestic cat displaying cutaneous lesions that tested positive for feline leukemia virus (FeLV) infection. Identification procedures employed both microscopic and molecular techniques, with molecular identification relying on ITS DNA sequencing. Enzymatic assays targeting lipase, phospholipase, protease, and keratinase yielded negative results, suggesting the prevalence of alternative virulence mechanisms. Successful treatment of the infection was achieved with itraconazole, and susceptibility testing confirmed its sensitivity to azoles and polyene antifungal drugs., (Copyright © 2024 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF