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2. Islet-after-kidney transplantation versus kidney alone in kidney transplant recipients with type 1 diabetes (KAIAK): a population-based target trial emulation in France

Author

Armanet, Mathieu, Auxenfans, Céline, Averland, Benoit, Benhamou, Pierre-Yves, Benotmane, Ilies, Berishvili, Ekaterine, Bertrand, Dominique, Blanot, Stéphane, Borot, Sophie, Branchereau, Julien, Broca, Christophe, Brunet, Valérie, Cattan, Pierre, Chaillous, Lucy, Chatauret, Nicolas, Cheisson, Gaelle, Ciacio, Oriana, Colosio, Charlotte, Cornuault, Mathieu, Cuellar, Emmanuel, Defortescu, Guillaume, Defrance, Frédérique, Deshayes, Aurélie, Divard, Gillian, Domet, Thomas, Duffas, Jean-Pierre, Elias, Michelle, Faivre, Lionel, Gaudez, François, Giral, Magali, Girerd, Sophie, Gmyr, Valery, Gouin, Philippe, Gregoire, Hélène, Gueguen, Juliette, Haidar, Fadi, Hubert, Thomas, Janbon, Bénédicte, Jeantet, Marine, Karam, Georges, Kerbaul, François, Kerleau, Clarisse, Kounis, Ilias, Laporte, Caroline, Laurent, Charlotte, Lejay, Anne, Masset, Christophe, Mazeaud, Charles, Mokri, Laëtitia, Moreau, Karine, Morellon, Emmanuel, Muscari, Fabrice, Nasone, Justine, Padilla, Marc, Parier, Bastien, Pastural, Myriam, Perrier, Quentin, Pittau, Gabriella, Prudhomme, Thomas, Renard, Eric, Raverdy, Violeta, Sá Cunha, António, Salloum, Chady, Seizilles De Mazancourt, Emilien, Snanoudj, Renaud, Thaunat, Oliver, Thuret, Rodolphe, Timsit, Marc-Oliver, Vachiery-Lahaye, Florence, Maanaoui, Mehdi, Lenain, Rémi, Foucher, Yohann, Buron, Fanny, Blancho, Gilles, Antoine, Corinne, Caillard, Sophie, Kessler, Laurence, Le Quintrec, Moglie, Villard, Orianne, Anglicheau, Dany, Büchler, Matthias, Brodin-Sartorius, Albane, Frimat, Luc, Malvezzi, Paolo, Lablanche, Sandrine, Badet, Lionel, Esposito, Laure, Chetboun, Mikael, Hamroun, Aghiles, Kerr-Conte, Julie, Berney, Thierry, Vantyghem, Marie-Christine, Hazzan, Marc, and Pattou, François

Published
2024
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3. Evaluation of a delayed liver transplantation strategy for patients with HCC receiving bridging therapy: the DELTA-HCC study

Author

Lamarque, Catherine, Segaux, Lauriane, Bachellier, Philippe, Buchard, Benjamin, Chermak, Faiza, Conti, Filomena, Decaens, Thomas, Dharancy, Sébastien, Di Martino, Vincent, Dumortier, Jérôme, Francoz-Caudron, Claire, Gugenheim, Jean, Hardwigsen, Jean, Muscari, Fabrice, Radenne, Sylvie, Salamé, Ephrem, Uguen, Thomas, Ursic-Bedoya, José, Antoine, Corinne, Deshayes, Aurélie, Jacquelinet, Christian, Natella, Pierre-André, Leroy, Vincent, Cherqui, Daniel, Oubaya, Nadia, and Duvoux, Christophe

Published
2024
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7. SAT-016 Assessment of the role of liver transplantation with or without combined kidney transplantation in polycystic liver or liver and kidney disease

Author

Lubuela, Gwladys, primary, Joly, Dominique, additional, Dondero, Federica, additional, Anglicheau, Dany, additional, Antoine, Corinne, additional, Legendre, Christophe, additional, Roux, Olivier, additional, Weiss, Emmanuel, additional, Lefaucheur, Carmen, additional, Mejean, Arnaud, additional, Hertig, Alexandre, additional, Dokmak, Safi, additional, Lesurtel, Mickael, additional, Durand, Francois, additional, and Francoz, Claire, additional

Published
2024
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8. SAT-010 Elaboration of a one-year mortality score for first elective liver transplantation recipients over 60 years based on the results of the french national cohort between 2007 and 2017

Author

Labruyere, Marie, primary, Sow, Amadou-Khalilou, additional, Antoine, Corinne, additional, Dharancy, Sebastien, additional, Dumortier, Jérôme, additional, Turco, Celia, additional, Di Martino, Vincent, additional, Weil-Verhoeven, Delphine, additional, Houssel-Debry, Pauline, additional, Conti, Filomena, additional, Francoz, Claire, additional, Pageaux, Georges-Philippe, additional, Mabrut, Jean-Yves, additional, Salamé, Ephrem, additional, Faitot, François, additional, Coilly, Audrey, additional, Hardwigsen, Jean, additional, Decaens, Thomas, additional, Chermak, Faiza, additional, Muscari, Fabrice, additional, Anty, Rodolphe, additional, Duvoux, Christophe, additional, Abergel, Armand, additional, Franza, Anne Minello, additional, Binquet, Christine, additional, and Latournerie, Marianne, additional

Published
2024
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11. Islet-after-kidney transplantation versus kidney alone in kidney transplant recipients with type 1 diabetes (KAIAK): a population-based target trial emulation in France

Author

Maanaoui, Mehdi, Lenain, Rémi, Foucher, Yohann, Buron, Fanny, Blancho, Gilles, Antoine, Corinne, Caillard, Sophie, Kessler, Laurence, Le Quintrec, Moglie, Villard, Orianne, Anglicheau, Dany, Büchler, Matthias, Brodin-Sartorius, Albane, Frimat, Luc, Malvezzi, Paolo, Lablanche, Sandrine, Badet, Lionel, Esposito, Laure, Chetboun, Mikael, Hamroun, Aghiles, Kerr-Conte, Julie, Berney, Thierry, Vantyghem, Marie-Christine, Hazzan, Marc, Pattou, François, Armanet, Mathieu, Auxenfans, Céline, Averland, Benoit, Benhamou, Pierre-Yves, Benotmane, Ilies, Berishvili, Ekaterine, Bertrand, Dominique, Blanot, Stéphane, Borot, Sophie, Branchereau, Julien, Broca, Christophe, Brunet, Valérie, Cattan, Pierre, Chaillous, Lucy, Chatauret, Nicolas, Cheisson, Gaelle, Ciacio, Oriana, Colosio, Charlotte, Cornuault, Mathieu, Cuellar, Emmanuel, Defortescu, Guillaume, Defrance, Frédérique, Deshayes, Aurélie, Divard, Gillian, Domet, Thomas, Duffas, Jean-Pierre, Elias, Michelle, Faivre, Lionel, Gaudez, François, Giral, Magali, Girerd, Sophie, Gmyr, Valery, Gouin, Philippe, Gregoire, Hélène, Gueguen, Juliette, Haidar, Fadi, Hubert, Thomas, Janbon, Bénédicte, Jeantet, Marine, Karam, Georges, Kerbaul, François, Kerleau, Clarisse, Kounis, Ilias, Laporte, Caroline, Laurent, Charlotte, Lejay, Anne, Masset, Christophe, Mazeaud, Charles, Mokri, Laëtitia, Moreau, Karine, Morellon, Emmanuel, Muscari, Fabrice, Nasone, Justine, Padilla, Marc, Parier, Bastien, Pastural, Myriam, Perrier, Quentin, Pittau, Gabriella, Prudhomme, Thomas, Renard, Eric, Raverdy, Violeta, Sá Cunha, António, Salloum, Chady, Seizilles De Mazancourt, Emilien, Snanoudj, Renaud, Thaunat, Oliver, Thuret, Rodolphe, Timsit, Marc-Oliver, and Vachiery-Lahaye, Florence

Abstract

Islet transplantation has been associated with better metabolic control and quality of life than insulin treatment alone, but direct evidence of its effect on hard clinical endpoints is scarce. We aimed to assess the effect of islet transplantation on patient-graft survival in kidney transplant recipients with type 1 diabetes.

Published
2024
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15. The role of donor hypertension and angiotensin II in the occurrence of early pancreas allograft thrombosis.

Author

Masset, Christophe, Branchereau, Julien, Buron, Fanny, Karam, Georges, Rabeyrin, Maud, Renaudin, Karine, Le Borgne, Florent, Badet, Lionel, Matillon, Xavier, Legendre, Christophe, Glotz, Denis, Antoine, Corinne, Giral, Magali, Dantal, Jacques, and Cantarovich, Diego

Subjects
HOMOGRAFTS, KIDNEY transplantation, ANGIOTENSIN II, RENIN-angiotensin system, PANCREAS, THROMBOSIS, HYPERTENSION
Abstract

Background: About 10-20% of pancreas allografts are still lost in the early postoperative period despite the identification of numerous detrimental risk factors that correlate with graft thrombosis. Methods: We conducted a multicenter study including 899 pancreas transplant recipients between 2000 and 2018. Early pancreas failure due to complete thrombosis, long-term pancreas, kidney and patient survivals were analyzed and adjusted to donor, recipient and perioperative variables using a multivariate cause-specific Cox model stratified to transplant centers. Results: Pancreas from donors with history of hypertension (6.7%), as well as with high body mass index (BMI), were independently associated with an increased risk of pancreas failure within the first 30 post-operative days (respectively, HR= 2.57, 95% CI from 1.35 to 4.89 and HR= 1.11, 95% CI from 1.04 to 1.19). Interaction term between hypertension and BMI was negative. Donor hypertension also impacted long-term pancreas survival (HR= 1.88, 95% CI from 1.13 to 3.12). However, when pancreas survival was calculated after the postoperative day 30, donor hypertension was no longer a significant risk factor (HR= 1.22, 95% CI from 0.47 to 3.15). A lower pancreas survival was observed in patients receiving a pancreas from a hypertensive donor without RAAS (Renin Angiotensin Aldosterone System) blockers compared to others (50% vs 14%, p < 0.001). Pancreas survival was similar among non-hypertensive donors and hypertensive ones under RAAS blockers. Conclusion: Donor hypertension was a significant and independent risk factor of pancreas failure. The well-known pathogenic role of renin-angiotensin-aldosterone system seems to be involved in the genesis of this immediate graft failure. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Recipient age influences survival after liver transplant: Results of the French national cohort 2007–2017.

Author

Lerosey, Lea, Ksiasek, Elea, Abrahamowicz, Michal, Antoine, Corinne, Dharancy, Sébastien, Dumortier, Jérôme, Doussot, Alexandre, Di Martino, Vincent, Houssel‐Debry, Pauline, Conti, Filomena, Francoz, Claire, Pageaux, Georges‐Philippe, Salame, Ephrem, Faitot, François, Coilly, Audrey, Hardwigsen, Jean, Decaens, Thomas, Chermak, Faiza, Muscari, Fabrice, and Anty, Rodolphe

Subjects
LIVER transplantation, KIDNEY transplantation, ARTIFICIAL respiration, SURGICAL complications, HEPATOCELLULAR carcinoma, AGE, SURVIVAL analysis (Biometry)
Abstract

Background: In recent years, age at liver transplantation (LT) has markedly increased. In the context of organ shortage, we investigated the impact of recipient age on post‐transplantation mortality. Methods: All adult patients who received a first LT between 2007 and 2017 were included in this cross‐sectional study. Recipients' characteristics at the time of listing, donor and surgery data, post‐operative complications and follow‐up of vital status were retrieved from the national transplantation database. The impact of age on 5‐year overall mortality post‐LT was estimated using a flexible multivariable parametric model which was also used to estimate the association between age and 10‐year net survival, accounting for expected age‐ and sex‐related mortality. Results: Among the 7610 patients, 21.4% were aged 60–65 years, and 15.7% over 65. With increasing age, comorbidities increased but severity of liver disease decreased. Older recipient age was associated with decreased observed survival at 5 years after LT (p <.001), with a significant effect particularly during the first 2 years. The linear increase in the risk of death associated with age does not allow any definition of an age's threshold for LT (p =.832). Other covariates associated with an increased risk of 5‐year death were dialysis and mechanical ventilation at transplant, transfusion during LT, hepatocellular carcinoma and donor age. Ten‐year flexible net survival analysis confirmed these results. Conclusion: Although there was a selection process for older recipients, increasing age at LT was associated with an increased risk of death, particularly in the first years after LT. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Evolution of HLA‐sensitization according to immunosuppressive therapy management among kidney transplant patients returning to dialysis between 2008 and 2019: A French retrospective study.

Author

Ferrari, Kevin, Aarnink, Alice, Ayav, Carole, Frimat, Luc, Couchoud, Cécile, Audry, Benoît, Antoine, Corinne, and Girerd, Sophie

Subjects
IMMUNOSUPPRESSIVE agents, KIDNEY transplantation, CHRONIC kidney failure, INFORMATION technology management, HEMODIALYSIS patients
Abstract

Background: The optimal management of immunosuppressive therapy (IT) after kidney allograft failure (KAF) remains controversial. Although maintaining IT may reduce HLA‐sensitization and improve access to retransplantation, it may also increase the rate of immunosuppression‐related complications. The overall impact on patient mortality is unknown. The main objective of this study was to compare the evolution of HLA‐sensitization 6 months after KAF according to IT management. Methods: Individual clinical and health care data were extracted from the French national end‐stage kidney disease registry (Renal Epidemiology and Information Network [REIN]) and the French National Health Data system (SNDS), respectively. Patients aged > 18 years returning to dialysis after KAF between January 2008 and December 2019 in Lorraine were included. Patients were classified into two groups, IT continuation or IT discontinuation. HLA‐sensitization was defined as an increase in incompatible graft rate (IGR) between KAF and 6 months post‐KAF (change to a higher predefined category (0%–5%), (5%–20%), (20%–50%), (50%–85%), (85%–95%), (95%–98%), (98%–100%)). Secondary outcome was patient survival according to IT management. Results: A total of 121 patients were included, 35 (29%) of whom continued IT. HLA‐sensitization after KAF tended to be higher in the "IT discontinuation" group (57% vs. 38% in the "IT continuation" group, p =.07). In multivariate analysis, IT continuation was associated with a lower increase in IGR (OR.37, 95% CI [.14;.93]). IT management was not associated with patient mortality. Conclusions: Continuation of IT after KAF was associated with less change in IGR and was not associated with excess mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Favorable Outcomes of Liver Transplantation from Controlled Circulatory Death Donors Using Normothermic Regional Perfusion Compared to Brain Death Donors

Author

Savier, Eric, Lim, Chetana, Rayar, Michel, Orlando, Francesco, Boudjema, Karim, Mohkam, Kayvan, Lesurtel, Mickael, Mabrut, Jean Yves, Pittau, Gabriella, Begdadi, Nassiba, Cherqui, Daniel, Adam, René, Dondero, Federica, Sepulveda, Ailton, Soubrane, Olivier, Bucur, Petru, Barbier, Louise, Salame, Ephrem, Jasseron, Carine, Antoine, Corinne, Riou, Bruno, and Scatton, Olivier

Published
2020
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24. Evaluation of a delayed liver transplant strategy for patients listed for hepatocellular carcinoma treated with resection or thermo-ablation as a bridge to liver transplantation; the DELTAS-HCC study

Author

Lamarque, Catherine, primary, Segaux, Lauriane, additional, Abergel, Armand, additional, Bachellier, Philippe, additional, Chermak, Faiza, additional, Coilly, Audrey, additional, Conti, Filomena, additional, Decaens, Thomas, additional, Dharancy, Sebastien, additional, Di Martino, Vincent, additional, Dumortier, Jérôme, additional, Francoz, Claire, additional, Gugenheim, Jean, additional, Hardwigsen, Jean, additional, Muscari, Fabrice, additional, Radenne, Sylvie, additional, Salamé, Ephrem, additional, Uguen, Thomas, additional, Bedoya, José Ursic, additional, Antoine, Corinne, additional, Leroy, Vincent, additional, Oubaya, Nadia, additional, and Duvoux, Christophe, additional

Published
2023
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28. Liver transplantation for hepatocellular carcinoma with extended criteria: performance and applicability of the AFP score after official adoption by the French Organ Sharing Organization ABM: 5-year outcomes

Author

Duvoux, Christophe, primary, Dumont, Mathilde Petiet, additional, Pageaux, Georges-Philippe, additional, Salamé, Ephrem, additional, Dumortier, Jérôme, additional, Radenne, Sylvie, additional, Dharancy, Sébastien, additional, Houssel-Debry, Pauline, additional, Bachellier, Philippe, additional, Chiche, Laurence, additional, Durand, Francois, additional, Muscari, Fabrice, additional, Gugenheim, Jean, additional, Conti, Filomena, additional, Hardwigsen, Jean, additional, Jacquelinet, Christian, additional, Antoine, Corinne, additional, Ngongang, Norbert, additional, Leroy, Vincent, additional, Decaens, Thomas, additional, Cherqui, Daniel, additional, and Oubaya, Nadia, additional

Published
2022
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32. [Perspectives for future development of the kidney paired donation programme in France]

Author

Combe, Julien, Hiller, Victor, Tercieux, Olivier, Audry, Benoît, Baudet, Jules, Malaquin, Géraldine, Kerbaul, François, Antoine, Corinne, Macher, Marie-Alice, Jacquelinet, Christian, Bastien, Olivier, Pastural, Myriam, École polytechnique (X), Centre de Recherche en Économie et Statistique (CREST), Ecole Nationale de la Statistique et de l'Analyse de l'Information [Bruz] (ENSAI)-École polytechnique (X)-École Nationale de la Statistique et de l'Administration Économique (ENSAE Paris)-Centre National de la Recherche Scientifique (CNRS), Institut Polytechnique de Paris (IP Paris), IA coopérative : équité, vie privée, incitations (FAIRPLAY), Ecole Nationale de la Statistique et de l'Analyse de l'Information [Bruz] (ENSAI)-École polytechnique (X)-École Nationale de la Statistique et de l'Administration Économique (ENSAE Paris)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale de la Statistique et de l'Analyse de l'Information [Bruz] (ENSAI)-École polytechnique (X)-École Nationale de la Statistique et de l'Administration Économique (ENSAE Paris)-Centre National de la Recherche Scientifique (CNRS)-Inria Saclay - Ile de France, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Institut Polytechnique de Paris (IP Paris)-Criteo AI Lab, Criteo [Paris]-Criteo [Paris], Laboratoire d'économie mathématique et de microéconomie appliquée (LEMMA), Université Paris-Panthéon-Assas, Paris School of Economics (PSE), Université Paris 1 Panthéon-Sorbonne (UP1)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École des hautes études en sciences sociales (EHESS)-École des Ponts ParisTech (ENPC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Paris Jourdan Sciences Economiques (PJSE), and Agence de la biomédecine [Saint-Denis la Plaine]

Subjects
Kidney exchange programme, Loi de bioéthique, Tissue and Organ Procurement, Bioethics law, Transplantation rénale à donneur vivant, Chaîne de donneur vivant, Living donor kidney transplantation, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, Kidney, Kidney Transplantation, Donor Selection, Programme d’échange croisé, Living Donors, Humans, Kidney paired donation, Don croisé, France, Living donor chain
Abstract

International audience; Almost one third of kidney donation candidates are incompatible (HLA and/or ABO) with their directed recipient. Kidney paired donation allows potential donors to be exchanged and gives access to a compatible kidney transplant. The Bioethics Law of 2011 authorised kidney paired donation in France with reciprocity between 2 incompatible “donor-recipient” pairs. A limited number of transplants have been performed due to a too restricted authorization compared to other European practices. This study presents the perspectives of the new Bioethics Law, enacted in 2021, which increases the authorised practices for kidney paired donation in France. The two simulated evolutions are the increase of the number of pairs involved in a kidney paired donation to 6 (against 2 currently) and the use of a deceased donor as a substitution to one of living donor. Different scenarios are simulated using data from the Agence de la Biomedecine; incompatible pairs registered in the kidney paired donation programme in France between December 2013 and February 2018 (78 incompatible pairs), incompatible transplants performed during the same period (476 incompatible pairs) and characteristics of deceased donors as well as proposals made over this period. Increasing the number of pairs has a limited effect on the number of transplants, which increases from 18 (23% of recipients) in the current system to 25 (32% of recipients) when 6 pairs can be involved. The use of a deceased donor significantly increases the number of transplants to 41 (52% of recipients). This study makes it possible to evaluate the increase in possibilities of kidney transplants by kidney paired donation following the new bioethics law. A working group and an information campaign for professionals and patients will be necessary for its implementation.; Près d’un tiers des candidats au don de rein présente une incompatibilité (HLA et/ou ABO) avec le receveur pour lequel il s’engage. Le don croisé permet d’échanger des donneurs potentiels et donne l’accès à une greffe rénale compatible. La loi de bioéthique de 2011 a autorisé le don croisé en France avec une réciprocité entre 2 paires « donneur-receveur » incompatibles. Un faible nombre de greffes a été réalisé du fait d’une autorisation trop limitée en comparaison à d’autres pratiques européennes. Cette étude présente les perspectives de la nouvelle loi de bioéthique, promulguée en 2021, qui élargit les pratiques autorisées pour le don croisé en France. Les deux évolutions simulées sont l’augmentation du nombre de paires engagées dans un échange croisé à 6 (contre 2 paires actuellement) et le recours à un donneur décédé en substitution à l’un des donneurs vivants. Différents scénarii sont simulés à partir des données de l’Agence de la biomédecine ; les paires incompatibles inscrites dans le programme de don croisé en France entre décembre 2013 et février 2018 (78 paires incompatibles), les greffes incompatibles réalisées au cours de la même période (476 paires incompatibles) et les caractéristiques des donneurs décédés ainsi que les propositions faites sur cette période. L’augmentation du nombre de paires a un effet limité sur le nombre de greffes, qui passe de 18 (23 % des receveurs) dans le système actuel à 25 (32 % des receveurs) lorsque 6 paires peuvent être engagées dans un échange croisé. Le recours à un donneur décédé augmente significativement le nombre de greffes, qui passe à 41 (52 % des receveurs). Cette étude permet d’évaluer l’augmentation des possibilités de greffes rénales par don croisé suite à la nouvelle loi de bioéthique. Un groupe de travail et une campagne d’information des professionnels et des patients seront nécessaires pour sa mise en œuvre, dont les résultats seront d’autant plus importants que la participation sera élevée.

Published
2022
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34. Successful Reuse of Kidney Graft After Early Recurrence of Primary Focal and Segmental Glomerulosclerosis

Author

Hamroun, Aghilès, primary, Gibier, Jean-Baptiste, additional, Maanaoui, Mehdi, additional, Lionet, Arnaud, additional, Gnemmi, Viviane, additional, Bouyé, Sébastien, additional, Fantoni, Jean-Christophe, additional, Averland, Benoît, additional, Antoine, Corinne, additional, Lenain, Rémi, additional, Hazzan, Marc, additional, and Provôt, François, additional

Published
2021
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35. Consensus statement on normothermic regional perfusion in donation after circulatory death: report from the European Society for Organ Transplantation's Transplant Learning Journey

Author

Jochmans, Ina, Hessheimer, Amelia J., Neyrinck, Arne P., Paredes, David, Bellini, Maria Irene, Dark, John H., Kimenai, Hendrikus J. A. N., Pengel, Liset H. M., Watson, Christopher J. E., Abelli, Massimo, Antoine, Corinne, Barrou, Benoît, Bello, Irene, Degezelle, Karlien, De Beule, Julie, De Carlis, Riccado, de Jonge, Jeroen, Foss, Stein, Huurman, Volkert A.L., Knight, Simon R., Lebreton, Guillaume, Ledoux, Didier, Manara, Alex, Miñambres, Eduardo, Rega, Filip, Rubino, Antonio, Ryan, Marian, Sage, Edouard, Savier, Eric, Schotsmans, Paul, Ticozelli, Elena, Vandendriessche, Katrien, Zanierato, Marinella, Project, ESOT Workstream 04 of the TLJ (Transplant Learning Journey), and Surgery

Subjects
medicine.medical_specialty, Consensus, Tissue and Organ Procurement, Statement (logic), MEDLINE, Regional perfusion, donation after circulatory death, Donation after circulatory death, guidelines, normothermic regional perfusion, solid organ transplantation, Organ transplantation, Humans, Medicine, Intensive care medicine, Transplantation, business.industry, Foundation (evidence), Organ Preservation, Organ Transplantation, Circulatory death, Tissue Donors, Death, Perfusion, Donation, business
Abstract

Normothermic regional perfusion (NRP) in donation after circulatory death (DCD) is a safe alternative to in situ cooling and rapid procurement. An increasing number of countries and centres are performing NRP, a technically and logistically challenging procedure. This consensus document provides evidence-based recommendations on the use of NRP in uncontrolled and controlled DCDs. It also offers minimal ethical, logistical and technical requirements that form the foundation of a safe and effective NRP programme. The present article is based on evidence and opinions formulated by a panel of European experts of Workstream 04 of the Transplantation Learning Journey project, which is part of the European Society for Organ Transplantation. ispartof: TRANSPLANT INTERNATIONAL vol:34 issue:11 pages:2019-2030 ispartof: location:Switzerland status: published

Published
2021

36. Regulations and Procurement Surgery in DCD Liver Transplantation:Expert Consensus Guidance from the International Liver Transplantation Society

Author

Hessheimer, Amelia J., Polak, Wojciech, Antoine, Corinne, Dondero Pozzo, Federica, Maluf, Daniel, Monbaliu, Diethard, Oniscu, Gabriel, Hessheimer, Amelia J., Polak, Wojciech, Antoine, Corinne, Dondero Pozzo, Federica, Maluf, Daniel, Monbaliu, Diethard, and Oniscu, Gabriel

Abstract

Donation after circulatory death (DCD) donors are an increasingly more common source of livers for transplantation in many parts of the world. Events that occur during DCD liver recovery have a significant impact on the success of subsequent transplantation. This working group of the International Liver Transplantation Society evaluated current evidence as well as combined experience and created this guidance on DCD liver procurement. Best practices for the recovery and transplantation of livers arising through DCD after euthanasia and organ procurement with super-rapid cold preservation and recovery as well as postmortem normothermic regional perfusion are described, as are the use of adjuncts during DCD liver procurement.

Published
2021

41. THU-498 - Evaluation of a delayed liver transplant strategy for patients listed for hepatocellular carcinoma treated with resection or thermo-ablation as a bridge to liver transplantation; the DELTAS-HCC study

Author

Lamarque, Catherine, Segaux, Lauriane, Abergel, Armand, Bachellier, Philippe, Chermak, Faiza, Coilly, Audrey, Conti, Filomena, Decaens, Thomas, Dharancy, Sebastien, Di Martino, Vincent, Dumortier, Jérôme, Francoz, Claire, Gugenheim, Jean, Hardwigsen, Jean, Muscari, Fabrice, Radenne, Sylvie, Salamé, Ephrem, Uguen, Thomas, Bedoya, José Ursic, Antoine, Corinne, Leroy, Vincent, Oubaya, Nadia, and Duvoux, Christophe

Published
2023
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43. Fulminant Hepatitis registred for Emergency Liver Transplantation in France. Epidemiology and Outcome: 1672

Author

Ichai, Philippe, Belghiti, Jacques, Boudjema, Karim, Boillot, Olivier, Ducerf, Christian, Suc, Bertand, Wolf, Philippe, Pruvot, François René, Soubrane, Olivier, Le Treut, Yves-Patrice, Cherqui, Daniel, Laurent, Hannoun, Pageaux, Georges-Philippe, Gugenheim, Jean, Letoublon, Christian, Chiche, Laurence, Saric, Jean, Mantion, Georges, Chipponi, Jacques, Castaing, Denis X., Antoine, Corinne, and Samuel, Didier

Published
2012

44. Preliminary results of transplantation with kidneys donated after cardiocirculatory determination of death: a French single-centre experience

Author

Abboud, Imad, Viglietti, Denis, Antoine, Corinne, Gaudez, François, Meria, Paul, Tariel, Edouard, Mongiat-Artus, Pierre, Desgranchamps, François, Roussin, France, Fieux, Fabienne, Jacob, Laurent, Randoux, Christine, Michel, Catherine, Flamant, Martin, Lefaucheur, Carmen, Pillebout, Evangeline, Serrato, Tomas, Peraldi, Marie-Noelle, and Glotz, Denis

Published
2012
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48. COVID-19 Infection in Kidney Transplant Recipients: Disease Incidence and Clinical Outcomes

Author

Elias, Michelle, primary, Pievani, Daniele, additional, Randoux, Christine, additional, Louis, Kevin, additional, Denis, Blandine, additional, Delion, Alexandra, additional, Le Goff, Océane, additional, Antoine, Corinne, additional, Greze, Clarisse, additional, Pillebout, Evangeline, additional, Abboud, Imad, additional, Glotz, Denis, additional, Daugas, Eric, additional, and Lefaucheur, Carmen, additional

Published
2020
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