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5,612 results on '"Antisense oligonucleotides"'

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1. The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cancer cells’ survival in NRAS/MAPK-driven melanoma

2. Isolectin B4 (IB4)-conjugated streptavidin for the selective knockdown of proteins in IB4-positive (+) nociceptors.

3. NLRP3‐directed antisense oligonucleotides reduce microglial immunoactivities in vitro.

4. Optical Biosensing of SARS-CoV-2 RNA Based on Positively Charged Poly-l-Lysine Functionalized Gold Nanoparticles.

5. A Review of the Toxicity and Side Effects of Nucleic Acid-based Bio/Nanomaterials.

6. Human angiotensin-converting enzyme 2–specific antisense oligonucleotides reduce infection with SARS-CoV-2 variants.

7. A therapeutic approach for the hepatitis C virus: in silico design of an antisense oligonucleotide-based candidate capsid inhibitor.

8. TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition.

9. SÍNDROME DE ANGELMAN: ABORDAJE ACTUAL Y EL FUTURO DE LAS TERAPIAS.

10. Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity.

11. Therapeutic Antisense Oligonucleotides in Oncology: From Bench to Bedside.

12. New insights into the therapeutic options to lower lipoprotein(a).

13. miRNA-targeting oligonucleotide constructs with various mechanisms of action as effective inhibitors of carcinogenesis

14. Splice modulation strategy applied to deep intronic variants in COL7A1 causing recessive dystrophic epidermolysis bullosa.

15. Advancing Nitrile‐Aminothiol Strategy for Dual and Sequential Bioconjugation.

16. Oligonucleotide Therapies for Facioscapulohumeral Muscular Dystrophy: Current Preclinical Landscape.

17. Is Exon Skipping a Viable Therapeutic Approach for Vascular Ehlers–Danlos Syndrome with Mutations in COL3A1 Exon 10 or 15?

18. FLI1 in PBMCs contributes to elevated inflammation in combat-related posttraumatic stress disorder.

19. In Vitro Studies to Evaluate the Intestinal Permeation of an Ursodeoxycholic Acid-Conjugated Oligonucleotide for Duchenne Muscular Dystrophy Treatment.

20. Allele-Selective Thiomorpholino Antisense Oligonucleotides as a Therapeutic Approach for Fused-in-Sarcoma Amyotrophic Lateral Sclerosis.

21. Identifying Cell-Penetrating Peptides for Effectively Delivering Antimicrobial Molecules into Streptococcus suis.

22. Genetic Interventions for Spinocerebellar Ataxia and Huntington's Disease: A Qualitative Study of the Patient Perspective.

23. Microrna-155 as a Possible Pharmacological Target.

24. Limb Girdle Muscular Dystrophy Type 2B (LGMD2B): Diagnosis and Therapeutic Possibilities.

25. Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.

26. A functional study reveals CsNAC086 regulated the biosynthesis of flavonols in Camellia sinensis.

27. The Coming Age of Antisense Oligos for the Treatment of Hepatic Ischemia/Reperfusion (IRI) and Other Liver Disorders: Role of Oxidative Stress and Potential Antioxidant Effect.

28. Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancerResearch in context

29. Antisense oligonucleotides and their applications in rare neurological diseases

31. Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment

33. Introduction of sugar-modified nucleotides into CpG-containing antisense oligonucleotides inhibits TLR9 activation

34. Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression

35. Mechanism of Action of Antisense Oligonucleotides and Their Research Progress in the Musculoskeletal System

36. Mechanistic insights into ASO-RNA complexation: Advancing antisense oligonucleotide design strategies

37. TNA‐Mediated Antisense Strategy to Knockdown Akt Genes for Triple‐Negative Breast Cancer Therapy.

38. Introduction of sugar-modified nucleotides into CpG-containing antisense oligonucleotides inhibits TLR9 activation.

39. Antisense Oligonucleotides for Rapid Translation of Gene Therapy in Glioblastoma.

40. Next-generation therapeutics for rare genetic disorders.

41. A Facile Synthesis of 3′-Fluoro Hexitol Adenosine and Guanosine Phosphoramidites.

42. Novel Therapies for Lipoprotein(a): Update in Cardiovascular Risk Estimation and Treatment.

43. Lipoprotein(a) and Atherosclerotic Cardiovascular Disease: Where Do We Stand?

44. A Precision Therapy Approach for Retinitis Pigmentosa 11 Using Splice-Switching Antisense Oligonucleotides to Restore the Open Reading Frame of PRPF31.

45. Synthesis of DNA‐Boron Cluster Composites and Assembly into Functional Nanoparticles with Dual, Anti‐EGFR, and Anti‐c‐MYC Oncogene Silencing Activity.

46. Elevated 4R tau contributes to endolysosomal dysfunction and neurodegeneration in VCP-related frontotemporal dementia.

47. An antisense oligonucleotide efficiently suppresses splicing of an alternative exon in vascular smooth muscle in vivo.

48. A nano-bioconjugate modified with anti-SIRPα antibodies and antisense oligonucleotides of mTOR for anti-atherosclerosis therapy.

49. Antisense and Functional Nucleic Acids in Rational Drug Development.

50. Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity

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