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138 results on '"Antirheumatic agents -- Dosage and administration"'

1. Data from Aligarh Muslim University Advance Knowledge in Antirheumatics (Methotrexate for Drug Repurposing As an Anti-aggregatory Agent To Mercuric Treated A-chymotrypsinogen-a)

Subjects
Diagnosis, Prevention, Care and treatment, Risk factors, Dosage and administration, Methods, Antirheumatic agents -- Dosage and administration, Parkinson disease -- Diagnosis -- Care and treatment, Alzheimer's disease -- Risk factors -- Prevention, Drug discovery -- Methods, Parkinson's disease -- Diagnosis -- Care and treatment
Abstract

2024 APR 20 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Drugs and Therapies - Antirheumatics. According to [...]

Published
2024

2. Investigators from Amgen Inc. Have Reported New Data on Antirheumatics (A Continuous Process for Manufacturing Apremilast. Part I: Process Development and Intensification By Utilizing Flow Chemistry Principles)

Subjects
Usage, Dosage and administration, Methods, Health aspects, Antirheumatic agents -- Dosage and administration, Crystallization -- Methods, Biopharmaceuticals -- Usage -- Health aspects, Biopharmaceutics -- Usage -- Health aspects
Abstract

2024 MAR 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Fresh data on Drugs and Therapies - Antirheumatics are presented in a [...]

Published
2024

3. Recent Findings in Pain Described by Researchers from Charite - University Medicine Berlin (Association of nociplastic and neuropathic pain components with the presence of residual symptoms in patients with axial spondyloarthritis receiving ...)

Subjects
Diagnosis, Care and treatment, Analysis, Measurement, Dosage and administration, Health aspects, Antirheumatic agents -- Dosage and administration, Radiography -- Analysis, Peripheral nervous system diseases -- Diagnosis -- Care and treatment, C-reactive protein -- Measurement -- Health aspects, Peripheral nerve diseases -- Diagnosis -- Care and treatment
Abstract

2024 MAR 9 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on pain have been presented. According to news originating from [...]

Published
2024

4. New Rheumatoid Arthritis Findings from Vanderbilt University Medical Center Described (Primary Medication Nonadherence Rates To Specialty Disease-modifying Antirheumatic Drugs for Rheumatoid Arthritis Within a Health System Specialty Pharmacy)

Subjects
Drug therapy, Analysis, Dosage and administration, Antirheumatic agents -- Dosage and administration, Rheumatoid arthritis -- Drug therapy, Pharmaceutical care -- Analysis, Patient compliance -- Analysis
Abstract

2023 SEP 16 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Autoimmune Diseases and Conditions - Rheumatoid Arthritis. [...]

Published
2023

5. Semmelweis University Researcher Reports on Findings in Antirheumatics (Enantioselective Human Serum Albumin Binding of Apremilast: Liquid Chromatographic, Fluorescence and Molecular Docking Study)

Subjects
Analysis, Measurement, Methods, Dosage and administration, Health aspects, High performance liquid chromatography -- Methods, Apremilast -- Dosage and administration, Drug interactions -- Analysis, Antirheumatic agents -- Dosage and administration, Fluorescence spectroscopy -- Methods, Albumin -- Measurement -- Health aspects
Abstract

2023 FEB 11 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on antirheumatics are discussed in a new report. According to [...]

Published
2023

6. Researchers from University of Colorado Report Recent Findings in Macular Edema (Non-biologic, Steroid-sparing Therapies for Non-infectious Intermediate, Posterior, and Panuveitis In Adults)

Subjects
Diagnosis, Care and treatment, Analysis, Patient outcomes, Dosage and administration, Antirheumatic agents -- Dosage and administration, Immunotherapy -- Patient outcomes, Immunosuppressive agents -- Dosage and administration, Cystoid macular edema -- Diagnosis -- Care and treatment, Data collection -- Analysis, Eye diseases -- Diagnosis -- Care and treatment, Data entry -- Analysis
Abstract

2022 DEC 17 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Eye Diseases and Conditions - Macular Edema are discussed [...]

Published
2022

7. New Antirheumatics Study Results Reported from Minia University (Dihydromyricetin Alleviates Methotrexate-induced Hepatotoxicity Via Suppressing The?tlr4/nf-kappa B Pathway and Nlrp3 Inflammasome/caspase 1 Axis)

Subjects
Complications and side effects, Analysis, Dosage and administration, Antirheumatic agents -- Dosage and administration, Drug toxicity -- Analysis, Methotrexate -- Dosage and administration -- Complications and side effects, Hepatocytes -- Analysis, Liver cells -- Analysis, Drugs -- Health aspects
Abstract

2022 NOV 26 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Drugs and Therapies - Antirheumatics are discussed in a [...]

Published
2022

8. Study Findings on Lung Cancer Published by Researchers at Jeonbuk National University (Anti-Cancer Effects of Auranofin in Human Lung Cancer Cells by Increasing Intracellular ROS Levels and Depleting GSH Levels)

Subjects
Diagnosis, Care and treatment, Analysis, Measurement, Dosage and administration, Health aspects, Lung cancer -- Diagnosis -- Care and treatment, Antirheumatic agents -- Dosage and administration, Cell proliferation -- Health aspects, Glutathione -- Measurement -- Health aspects, Reactive oxygen species -- Analysis
Abstract

2022 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on lung cancer is now available. According to news [...]

Published
2022

9. Data on Rheumatoid Arthritis Detailed by Researchers at Beijing University of Chinese Medicine (<p>intestinal Metabolism and Absorption Mechanism of Multi-components In Gaultheria Leucocarpa Var. Yunnanensis- an Assessment Using In Situ and In ...)

Subjects
Diagnosis, Care and treatment, Risk factors, Methods, Dosage and administration, Rheumatoid arthritis -- Risk factors -- Diagnosis -- Care and treatment, Antirheumatic agents -- Dosage and administration, Asian medicine -- Methods, Medicine, Oriental -- Methods
Abstract

2022 JUN 18 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Autoimmune Diseases and Conditions - Rheumatoid Arthritis are discussed [...]

Published
2022

10. Research from University of Lisbon in the Area of Juvenile Rheumatoid Arthritis Published (B Cells on the Stage of Inflammation in Juvenile Idiopathic Arthritis: Leading or Supporting Actors in Disease Pathogenesis?)

Subjects
Diagnosis, Care and treatment, Analysis, Risk factors, Dosage and administration, Antirheumatic agents -- Dosage and administration, Rheumatoid factor -- Analysis, Juvenile rheumatoid arthritis -- Risk factors -- Diagnosis -- Care and treatment, Nonsteroidal anti-inflammatory agents -- Dosage and administration, Immune response -- Analysis
Abstract

2022 APR 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in juvenile rheumatoid arthritis. According to news reporting [...]

Published
2022

11. King Faisal University Researchers Further Understanding of Antirheumatics [Risedronate and Methotrexate Are High-Affinity Inhibitors of New Delhi Metallo-b-Lactamase-1 (NDM-1): A Drug Repurposing Approach]

Subjects
Care and treatment, Analysis, Dosage and administration, Antirheumatic agents -- Dosage and administration, Beta lactamases -- Analysis, Microbial drug resistance -- Care and treatment, Antibacterial agents -- Dosage and administration, Drug resistance in microorganisms -- Care and treatment
Abstract

2022 MAR 19 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on antirheumatics is the subject of a new report. According [...]

Published
2022

12. Investigators from Hanyang University Report New Data on Herpes Zoster Virus (Risk Factors for Herpes Zoster In Korean Patients With Rheumatoid Arthritis Treated With Jak Inhibitor: a Nested Case-control Study)

Subjects
Prevention, Complications and side effects, Risk factors, Dosage and administration, Rheumatoid arthritis -- Complications and side effects, Antirheumatic agents -- Dosage and administration, Janus kinase -- Dosage and administration, Herpes zoster -- Risk factors -- Prevention, Shingles (Disease) -- Risk factors -- Prevention
Abstract

2022 MAR 5 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Herpesvirus Diseases and Conditions - Herpes Zoster [...]

Published
2022

13. Psoriatic Arthritis: Types, Causes, Symptoms & Treatments

Author

Bradley, Miriam Jones

Subjects
Diagnosis, Care and treatment, Genetic aspects, Dosage and administration, Antirheumatic agents -- Dosage and administration, Tumor necrosis factor inhibitors -- Dosage and administration, Nonsteroidal anti-inflammatory agents -- Dosage and administration, Psoriatic arthritis -- Diagnosis -- Care and treatment -- Genetic aspects, Nonsteroidal anti-inflammatory drugs -- Dosage and administration
Published
2023

14. The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

Subjects
Care and treatment, Usage, Complications and side effects, Research, Risk factors, Dosage and administration, Antirheumatic agents -- Dosage and administration, Rheumatoid arthritis -- Care and treatment -- Complications and side effects, Dysbiosis -- Risk factors, Microbiota (Symbiotic organisms) -- Research, DNA sequencing -- Usage, Nucleotide sequencing -- Usage
Abstract

RA is an autoimmune disorder affecting tens of millions of people worldwide and is associated with increased mortality owing to cardiovascular and other systemic complications. However, the etiology of RA [...], We carried out metagenomic shotgun sequencing and a metagenome-wide association study (MGWAS) of fecal, dental and salivary samples from a cohort of individuals with rheumatoid arthritis (RA) and healthy controls. Concordance was observed between the gut and oral microbiomes, suggesting overlap in the abundance and function of species at different body sites. Dysbiosis was detected in the gut and oral microbiomes of RA patients, but it was partially resolved after RA treatment. Alterations in the gut, dental or saliva microbiome distinguished individuals with RA from healthy controls, were correlated with clinical measures and could be used to stratify individuals on the basis of their response to therapy. In particular, Haemophilus spp. were depleted in individuals with RA at all three sites and negatively correlated with levels of serum autoantibodies, whereas Lactobacillus salivarius was over-represented in individuals with RA at all three sites and was present in increased amounts in cases of very active RA. Functionally, the redox environment, transport and metabolism of iron, sulfur, zinc and arginine were altered in the microbiota of individuals with RA. Molecular mimicry of human antigens related to RA was also detectable. Our results establish specific alterations in the gut and oral microbiomes in individuals with RA and suggest potential ways of using microbiome composition for prognosis and diagnosis.

Published
2015
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15. Juvenile idiopathic arthritis: rethinking remission

Author

Nierengarten, Mary Beth and Oski, Jane A.

Subjects
Drug therapy, Diagnosis, Case studies, Risk factors, Patient outcomes, Dosage and administration, Antirheumatic agents -- Dosage and administration, Juvenile arthritis -- Drug therapy -- Diagnosis -- Risk factors -- Patient outcomes -- Case studies
Abstract

New research looks at the emerging evidence on the biology of remission that holds promise for better outcomes for patients with JIA. Juvenile idiopathic arthritis (JIA) refers to a heterogenous [...]

Published
2014

16. Herpes simplex encephalitis during treatment with tumor necrosis factor-(alpha) inhibitors

Author

Bradford, Russell D., Pettit, April C., Wright, Patty W., Mulligan, Mark J., Moreland, Larry W., McLain, David A., Gnann, John W., and Bloch, Karen C.

Subjects
Herpes simplex encephalitis -- Risk factors, Herpes simplex encephalitis -- Case studies, Tumor necrosis factor -- Physiological aspects, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Complications and side effects, Health, Health care industry
Published
2009

17. Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial

Author

Grigor, Catriona, Capell, Hilary, Stirling, Anne, McMahon, Alex D., Lock, Peter, Vallance, Ramsay, Kincaid, Wilma, and Porter, Duncan

Subjects
Ambulatory medical care -- Health aspects, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Health aspects, Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Patient outcomes
Published
2004

18. Drug therapy: new drugs for rheumatoid arthritis

Author

Olsen, Nancy J. and Stein, C. Michael

Subjects
Rheumatoid arthritis -- Drug therapy, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Properties
Abstract

The properties of various new drugs for Rheumatoid arthritis, affecting approximately 1 percent of the U.S. population, are reviewed. Adverse effects and clinical use of the antagonists in rheumatoid arthritis are presented.

Published
2004

19. Current standards and future treatments of rheumatoid arthritis

Author

Onysko, Mary and Burch, Jessica

Subjects
Drug therapy, Care and treatment, Dosage and administration, Rheumatoid arthritis -- Drug therapy -- Care and treatment, Antirheumatic agents -- Dosage and administration, Practice guidelines (Medicine)
Abstract

Rheumatoid arthritis (RA) is an autoimmune disease that has significant progressive morbidity, many extra-articular complications, higher mortality rates than the general population, and considerable socioeconomic costs. (1-3) The disease is [...], Rheumatoid arthritis (RA) is an autoimmune disorder in which the immune system targets synovial joints and causes mild-to-severe joint disease with extra-articular manifestations. RA is associated with significant disability and socioeconomic costs because it is estimated to affect up to 1% of the adult population in the United States. Greater understanding of the process of RA has led to new treatments emerging for the disease that target its pathogenesis instead of its symptoms. This review discusses the current standards of care and details the most recent data being collected on new pharmacologic agents for the treatment of RA. (Formulary. 2012; 47:359-368.)

Published
2012

20. Treatment of rheumatoid arthritis: a review of recommendations and emerging therapy

Author

Clements, Jennifer N.

Subjects
Drug therapy, Diagnosis, Complications and side effects, Development and progression, Risk factors, Dosage and administration, Methods, Laws, regulations and rules, Government regulation, Rheumatoid arthritis -- Complications and side effects -- Drug therapy -- Risk factors -- Development and progression -- Diagnosis, Antirheumatic agents -- Dosage and administration, Therapeutics -- Laws, regulations and rules -- Methods, Homeopathy -- Materia medica and therapeutics
Abstract

* Abstract Rheumatoid arthritis (RA) is a complex disease, resulting in localized erosion to the joint and its accessory structures. Due to the progressive nature of the disease, extra-articular complications [...]

Published
2011

21. Decrease in sick leave among patients with rheumatoid arthritis in the first 12 months after start of treatment with tumour necrosis factor antagonists: a population-based controlled cohort study

Author

Olofsson, Tor, Englund, Martin, Saxne, Tore, Joud, Anna, Jacobsson, Lennart T.H., Geborek, Pierre, Allaire, Saralynn, and Petersson, Ingemar F.

Subjects
Rheumatoid arthritis -- Drug therapy, Rheumatoid arthritis -- Prognosis, Rheumatoid arthritis -- Research, Sick leave -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Health
Published
2010

22. Decrease in serum level of matrix metalloproteinases is predictive of the disease-modifying effect of osteoarthritis drugs assessed by quantitative MRI in patients with knee osteoarthritis

Author

Pelletier, J.-P., Raynauld, J.-P., Caron, J., Mineau, F., Abram, F., Dorais, M., Haraoui, B., Choquette, D., and Martel-Pelletier, J.

Subjects
Interleukin-6 -- Measurement, Interleukin-6 -- Physiological aspects, Interleukin-6 -- Research, Metalloproteins -- Physiological aspects, Metalloproteins -- Research, Metalloproteins -- Measurement, Osteoarthritis -- Drug therapy, Osteoarthritis -- Patient outcomes, Osteoarthritis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, C-reactive protein -- Physiological aspects, C-reactive protein -- Research, C-reactive protein -- Measurement, Health
Published
2010

23. Predictors of treatment response and drug continuation in 842 patients with ankylosing spondylitis treated with anti-tumour necrosis factor: results from 8 years' surveillance in the Danish nationwide DANBIO registry

Author

Glintborg, Bente, Ostergaard, Mikkel, Krogh, Niels Steen, Dreyer, Lene, Kristensen, Hanne Lene, and Hetland, Merete Lund

Subjects
Ankylosing spondylitis -- Care and treatment, Ankylosing spondylitis -- Patient outcomes, Ankylosing spondylitis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Tumor necrosis factor -- Physiological aspects, Tumor necrosis factor -- Research, Treatment outcome -- Research, Health
Published
2010

24. State-of-the-art: rheumatoid arthritis

Author

McInnes, Iain B. and O'Dell, James R.

Subjects
Rheumatoid arthritis -- Development and progression, Rheumatoid arthritis -- Care and treatment, Cytokines -- Physiological aspects, Antirheumatic agents -- Dosage and administration, Drug therapy, Combination, Health
Published
2010

26. Trends in treatment and outcomes of rheumatoid arthritis in Germany 1997-2007: results from the National Database of the German Collaborative Arthritis Centres

Author

Ziegler, Stefanie, Huscher, Dorte, Karberg, Kirsten, Krause, Andreas, Wassenberg, Siegfried, and Zink, Angela

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Patient outcomes, Rheumatoid arthritis -- Forecasts and trends, Rheumatoid arthritis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Market trend/market analysis, Health
Published
2010

27. Serious infections in patients with ankylosing spondylitis with and without TNF blockers: a systematic review and meta-analysis of randomised placebo-controlled trials

Author

Fouque-Aubert, Anne, Jette-Paulin, Laetitia, Combescure, Christophe, Basch, Andre, Tebib, Jacques, and Gossec, Laure

Subjects
Ankylosing spondylitis -- Care and treatment, Ankylosing spondylitis -- Complications and side effects, Ankylosing spondylitis -- Research, Infection -- Risk factors, Infection -- Demographic aspects, Infection -- Research, Tumor necrosis factor -- Physiological aspects, Tumor necrosis factor -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Complications and side effects, Antirheumatic agents -- Research, Health
Published
2010

28. IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

Author

Verri, Waldiceu A., Jr., Souto, Fabricio O., Vieira, Silvio M., Almeida, Sergio C.L., Fukada, Sandra, Xu, Damo, Alves-Filho, Jose C., Cunha, Thiago M., Guerrero, Ana T.G., Mattos-Guimaraes, Rafaela B., Oliveira, Fabiola R., Teixeira, Mauro M., Silva, Joao S., McInnes, Iain B., Ferreira, Sergio H., Louzada-Junior, Paulo, Liew, Foo Y., and Cunha, Fernando Q.

Subjects
Rheumatoid arthritis -- Development and progression, Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Models, Rheumatoid arthritis -- Research, Interleukins -- Physiological aspects, Interleukins -- Research, Neutrophils -- Physiological aspects, Neutrophils -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Cell migration -- Research, Health
Published
2010

29. Lack of effect of TNF(alpha) blockade therapy on circulating adiponectin levels in patients with autoimmune disease: results from two independent prospective studies

Author

Peters, Mike J.L., Watt, Pauline, Cherry, Lynne, Welsh, Paul, Henninger, Eric, Dijkmans, Ben A.C., McInnes, Iain B., Nurmohamed, Michael T., and Sattar, Naveed

Subjects
Protein hormones -- Physiological aspects, Protein hormones -- Research, Autoimmune diseases -- Care and treatment, Autoimmune diseases -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Tumor necrosis factor -- Physiological aspects, Tumor necrosis factor -- Research, Health
Published
2010

30. Patients with RA in remission on TNF blockers: when and in whom can TNF blocker therapy be stopped?

Author

Saleem, Benazir, Keen, Helen, Goeb, Vincent, Parmar, Rekha, Nizam, Sharmin, Hensor, Elizabeth M.A., Churchman, Sarah M., Quinn, Mark, Wakefield, Richard, Conaghan, Philip G., Ponchel, Frederique, and Emery, Paul

Subjects
Rheumatoid arthritis -- Drug therapy, Rheumatoid arthritis -- Patient outcomes, Rheumatoid arthritis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Complications and side effects, Antirheumatic agents -- Research, Drug therapy, Combination -- Research, Methotrexate -- Dosage and administration, Methotrexate -- Complications and side effects, Methotrexate -- Research, Health
Published
2010

31. Risk of elevated liver enzymes associated with TNF inhibitor utilisation in patients with rheumatoid arthritis

Author

Sokolove, Jeremy, Strand, Vibeke, Greenberg, Jeffrey D., Curtis, Jeffrey R., Kavanaugh, Arthur, Kremer, Joel M., Anofrei, Alina, Reed, George, Calabrese, Leonard, Hooper, Michele, Baumgartner, Scott, and Furst, Daniel E.

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Complications and side effects, Rheumatoid arthritis -- Research, Liver function tests -- Analysis, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Complications and side effects, Antirheumatic agents -- Research, Aminotransferases -- Physiological aspects, Aminotransferases -- Research, Health
Published
2010

32. The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: methodological report phase 1

Author

Funovits, Julia, Aletaha, Daniel, Bykerk, Vivian, Combe, Bernard, Dougados, Maxime, Emery, Paul, Felson, David, Hawker, Gillian, Hazes, Joanna M., Huizinga, Tom, Kay, Jonathan, Kvien, Tore K., Smolen, Josef S., Symmons, Deborah, Tak, Paul P., and Silman, Alan

Subjects
Antirheumatic agents -- Dosage and administration, Rheumatoid arthritis -- Diagnosis, Rheumatoid arthritis -- Care and treatment, Practice guidelines (Medicine) -- Reports, Health, American College of Rheumatology -- Standards, American College of Rheumatology -- Reports
Published
2010

33. The Arthritis Today guide to DMARDs

Author

Dunkin, Mary Anne

Subjects
Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Complications and side effects, Rheumatoid arthritis -- Care and treatment, Health
Published
2010

34. Tumour necrosis factor alpha blockade impairs dendritic cell survival and function in rheumatoid arthritis

Author

Baldwin, Helen M., Ito-Ihara, Toshiko, Isaacs, John D., and Hilkens, Catharien M.U.

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Research, Tumor necrosis factor -- Physiological aspects, Tumor necrosis factor -- Research, Dendritic cells -- Physiological aspects, Dendritic cells -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Health
Published
2010

35. Economic aspects of treatment options in rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis

Author

Schoels, Monika, Wong, John, Scott, David L., Zink, Angela, Richards, Pamela, Landewe, Robert, Smolen, Josef S., and Aletaha, Daniel

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Economic aspects, Rheumatoid arthritis -- Research, Medical care, Cost of -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Economic aspects, Antirheumatic agents -- Research, Health
Published
2010

36. Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis

Author

Knevel, R., Schoels, M., Huizinga, T.W.J., Aletaha, D., Burmester, G.R., Combe, B., Landewe, R.B., Smolen, J.S., Sokka, T., and van der Heijde, D.M.F.M.

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Research, Practice guidelines (Medicine) -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Health
Published
2010

37. Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA

Author

Nam, J.L., Winthrop, K.L., van Vollenhoven, R.F., Pavelka, K., Valesini, G., Hensor, E.M.A., Worthy, G., Landewe, R., Smolen, J.S., Emery, P., and Buch, M.H.

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Complications and side effects, Antirheumatic agents -- Research, Corticosteroids -- Dosage and administration, Corticosteroids -- Complications and side effects, Corticosteroids -- Research, Bacterial infections -- Risk factors, Bacterial infections -- Research, Tuberculosis -- Risk factors, Tuberculosis -- Research, Health
Published
2010

38. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

Author

Smolen, Josef S., Landewe, Robert, Breedveld, Ferdinand C., Dougados, Maxime, Emery, Paul, Gaujoux-Viala, Cecile, Gorter, Simone, Knevel, Rachel, Nam, Jackie, Schoels, Monika, Aletaha, Daniel, Bush, Maya, Gossec, Laure, Huizinga, Tom, Bijlsma, Johannes W.J.W., Burmester, Gerd, Combe, Bernard, Cutolo, Maurizio, Gabay, Cem, Gomez-Reino, Juan, Kouloumas, Marios, Kvien, Tore K., Martin-Mola, Emilio, McInnes, Iain, Pavelka, Karel, van Riel, Piet, Scholte, Marieke, Scott, David L., Sokka, Tuulikki, Valesini, Guido, van Vollenhoven, Ronald, Winthrop, Kevin L., Wong, John, Zink, Angela, and van der Heijde, Desiree

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Corticosteroids -- Dosage and administration, Corticosteroids -- Research, Practice guidelines (Medicine), Health
Published
2010

40. Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial

Author

Coombs, J.H., Bloom, B.J., Breedveld, F.C., Fletcher, M.P., Gruben, D., Kremer, J.M., Burgos-Vargas, R., Wilkinson, B., Zerbini, C.A.F., and Zwillich, S.H.

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Research, Rheumatoid arthritis -- Patient outcomes, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Protein tyrosine kinase -- Physiological aspects, Protein tyrosine kinase -- Research, Clinical trials -- Reports, Arthralgia -- Care and treatment, Arthralgia -- Research, Health
Published
2010

41. Lymphoma in patients treated with anti-TNF: results of the 3-year prospective French RATIO registry

Author

Mariette, X., Tubach, F., Bagheri, H., Bardet, M., Berthelot, J.M., Gaudin, P., Heresbach, D., Martin, A., Schaeverbeke, T., Salmon, D., Lemann, M., Hermine, O., Raphael, M., and Ravaud, P.

Subjects
Lymphomas -- Risk factors, Lymphomas -- Demographic aspects, Lymphomas -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Complications and side effects, Antirheumatic agents -- Research, Monoclonal antibodies -- Research, Tumor necrosis factor -- Research, Health
Published
2010

42. DAS-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis

Author

Goekoop-Ruiterman, Y.P.M., de Vries-Bouwstra, J.K., Kersten, P.J.S.M., Nielen, M.M.J., Vos, K., van Schaardenburg, D., Speyer, I., Seys, P.E.H., Breedveld, F.C., Allaart, C.F., and Dijkmans, B.A.C.

Subjects
Rheumatoid arthritis -- Care and treatment, Rheumatoid arthritis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Health
Published
2010

43. Treatment of very early rheumatoid arthritis with symptomatic therapy, disease-modifying antirheumatic drugs, or biologic agents: a cost-effectiveness analysis

Author

Finckh, Axel, Bansback, Nick, Marra, Carlo A., Anis, Aslam H., Michaud, Kaleb, Lubin, Stanley, White, Marc, Sizto, Sonia, and Liang, Matthew H.

Subjects
Rheumatoid arthritis -- Drug therapy, Rheumatoid arthritis -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Health
Abstract

Background: Long-term control or remission of rheumatoid arthritis (RA) may be possible with very early treatment. However, no optimal first therapeutic strategy has been determined. Objective: To assess the potential cost-effectiveness of major therapeutic strategies for very early RA. Design: Decision analytic model with probabilistic sensitivity analyses. Data Sources: Published data, the National Data Bank for Rheumatic Diseases, and actual 2007 hospital costs. Target Population: U.S. adults with very early RA (symptom duration [less than or equal to] 3 months). Time Horizon: Lifetime. Perspective: Health care provider and societal. Intervention: 3 management strategies were compared: a symptomatic or 'pyramid' strategy with initial nonsteroidal anti-inflammatory drugs, patient education, pain management, and low-dose glucocorticoids, and disease-modifying antirheumatic drugs (DMARDs) at 1 year for nonresponders; early DMARD therapy with methotrexate; and early therapy with biologics and methotrexate. Outcome Measures: Cost per quality-adjusted life-year (QALY) gained. Results of Base-Case Analysis: By reducing the progression of joint erosions and subsequent functional disability, both early intervention strategies increase quality-adjusted life more than the pyramid strategy and save long-term costs. When the cost of very early intervention is factored in, the cost-effectiveness ratio of the early DMARD strategy is $4849 per QALY (95% Cl, $0 to $16 354 per QALY) compared with the pyramid strategy, whereas the benefits gained through the early biologic strategy come at a substantial incremental cost. The early DMARD strategy maximizes the effectiveness of early DMARDs and reserves the use of biologics for patients with more treatment-resistant disease of longer duration, for which the incremental benefit of biologics is greater. Results of Sensitivity Analysis: The early biologic strategy becomes more cost-effective if drug prices are reduced, risk for death is permanently lowered through biologic therapy, patients experience drug-free remission, responders can be selected before therapy initiation, or effective alternative antirheumatic agents are available for patients for whom several biologics have failed. Limitations: Data on the long-term effect of very early therapeutic interventions on the natural progression in disability and joint erosions are limited. The study considered only tumor necrosis factor inhibitors and not the newer biologics. Conclusion: According to the most objective measures of RA progression, very early intervention with conventional DMARDs is cost-effective. The cost-effectiveness of very early intervention with biologics remains uncertain.

Published
2009

44. Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database

Author

Sokka, T., Kautiainen, H., Pincus, T., Toloza, S., da Rocha Castelar Pinheiro, G., Lazovskis, J., Hetland, M.L., Peets, T., Immonen, K., Maillefert, J.F., Drosos, A.A., Alten, R., Pohl, C., Rojkovich, B., Bresnihan, B., Minnock, P., Cazzato, M., Bombardieri, S., Rexhepi, S., Rexhepi, M., Andersone, D., Stropuviene, S., Huisman, M., Sierakowski, S., Karateev, D., Skakic, V., Naranjo, A., Baecklund, E., Henrohn, D., Gogus, F., Badsha, H., Mofti, A., Taylor, P., McClinton, C., and Yazici, Y.

Subjects
Rheumatoid arthritis -- Development and progression, Rheumatoid arthritis -- Demographic aspects, Rheumatoid arthritis -- Distribution, Rheumatoid arthritis -- Research, Gross domestic product -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Company distribution practices, Health
Published
2009

45. European biologicals registers: methodology, selected results and perspectives

Author

Zink, A., Askling, J., Dixon, W.G., Klareskog, L., Silman, A.J., and Symmons, D.P.M.

Subjects
Registries (in medicine) -- Standards, Rheumatoid arthritis -- Drug therapy, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Licensing, certification and accreditation, Health
Published
2009

46. Efficacy and safety of certolizumab pegol monotherapy every 4 weeks in patients with rheumatoid arthritis failing previous disease-modifying antirheumatic therapy: the FAST4WARD study

Author

Fleischmann, R., Vencovsky, J., van Vollenhoven, R.F., Borenstein, D., Box, J., Coteur, G., Goel, N., Brezinschek, H.-P., Innes, A., and Strand, V.

Subjects
Rheumatoid arthritis -- Drug therapy, Rheumatoid arthritis -- Patient outcomes, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Health aspects, Drug therapy -- Usage, Drug therapy -- Patient outcomes, Health, American College of Rheumatology -- Standards
Published
2009

47. The effectiveness and medication costs of three anti-tumour necrosis factor [alpha] agents in the treatment of rheumatoid arthritis from prospective clinical practice data

Author

Kievit, W., Adang, E.M., Fransen, J., Kuper, H.H., van de Laar, M.A.F.J., Jansen, T.L., De Gendt, C.M.A., De Rooij, D.-J.R.A.M., Brus, H.L.M., Van Oijen, P.C.M., and Van Riel, P.C.L.M.

Subjects
Rheumatoid arthritis -- Drug therapy, Rheumatoid arthritis -- Economic aspects, Rheumatoid arthritis -- Patient outcomes, Rheumatoid arthritis -- Research, Medical care, Cost of -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Tumor necrosis factor -- Physiological aspects, Health
Published
2008

48. Do changes in prescription practice in patients with rheumatoid arthritis treated with biological agents affect treatment response and adherence to therapy? Results from the nationwide Danish DANBIO Registry

Author

Hetland, M.L., Lindegaard, H.M., Hansen, A., Podenphant, J., Unkerskov, J., Ringsdal, V.S., Ostergaard, M., and Tarp, U.

Subjects
Rheumatoid arthritis -- Drug therapy, Rheumatoid arthritis -- Patient outcomes, Rheumatoid arthritis -- Research, Prescription writing -- Influence, Patient compliance -- Research, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Drug therapy -- Patient outcomes, Drug therapy -- Research, Health
Published
2008

49. Anti-tumour necrosis factor treatment in patients with refractory systemic vasculitis associated with rheumatoid arthritis

Author

Puechal, X., Miceli-Richard, C., Mejjad, O., Lafforgue, P., Marcelli, C., Solau-Gervais, E., Steinfeld, S., Villoutreix, C., Treves, R., Mariette, X., and Guillevin, L.

Subjects
Tumor necrosis factor -- Physiological aspects, Vasculitis -- Care and treatment, Rheumatoid arthritis -- Complications and side effects, Rheumatoid arthritis -- Care and treatment, Antirheumatic agents -- Dosage and administration, Antirheumatic agents -- Research, Health
Published
2008

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