269 results on '"Antioksidanlar"'
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2. The role of oxidative stress and antioxidants in older individuals with osteoporotic hip fractures.
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Aydın, Mustafa and Avcı, Emre
- Abstract
Copyright of Turkish Journal of Trauma & Emergency Surgery / Ulusal Travma ve Acil Cerrahi Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2025
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3. Wood Ash Liquid Fertilizer as Sustainable Soil Nutritional Supplement Modulates Changes on Growth and Fruits Nutritional Compositions of Capsicum frutescens L.
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Racheal Tope-akinyetun, Zainab Mustapha, Musa Hussaini, Temitayo Kelani, and Anthony Ojewumi
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antioksidanlar ,flavonoidler ,büyüme bileşenleri ,toprak düzenleyiciler ,net asimilasyon oranı ,göreceli büyüme oranı ,antioxidants ,flavonoids ,growth components ,soil conditioners ,net assimilation rate ,relative growth rate ,Agriculture - Abstract
The use of plant-derived fertilizers is a promising approach towards sustainable crop production. This study exploited supplementary effects of 100, 75, 50, and 25% wood ash liquid fertilizer (WALF) on the growth and fruit nutritional contents of Capsicum frutescens. Ordinary water served as control. Agronomical, physiological, and fruit nutritional parameters of the pepper were determined. Higher plant height (25.17 cm) was observed in pepper seedlings sprayed with 25% WALF while several leaves (71.20), leaf area (100.62 cm2), specific leaf area (67.14 m2kg-1), and leaf area index (0.31 m2m-2) were higher (p
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- 2025
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4. CONVECTIVE DRYING OF CHOKEBERRY CV. "VIKING" AND MODELING OF DRYING KINETICS.
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ÜNAL, Nafiye, SÜSLÜ, Ahmet, KÜLCÜ, Recep, DINCER, Cüneyt, YAVUZLAR IMIRGI, Eda Elif, and ERTEKIN, Can
- Subjects
- *
ATMOSPHERIC temperature , *ARONIA , *FRUIT quality , *ROSACEAE , *VELOCITY - Abstract
In this study, the effects of drying air temperatures (50, 60, 70, and 80°C) and velocities (0.5, 0.8, and 1.2 m/s) on chokeberry quality during convective drying were evaluated. The drying time decreased significantly with increasing drying air temperatures and velocities, from 2265 minutes at 50°C to 195 minutes at 80°C, and from 360 minutes at 0.5 m/s to 240 minutes at 1.2 m/s at 70°C. Higher drying air temperatures and velocities also enhanced the fruit color quality. The best antioxidant activity, anthocyanin, and phenolic content were achieved at 70°C with dryin air velocities between 0.5 m/s and 1.2 m/s. The Midilli et al. model provided the best fit for the drying kinetics, with high accuracy (R²≥0.9978, χ²≤0.0003, RMSE≤0.0161). [ABSTRACT FROM AUTHOR]
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- 2024
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5. The effect of acute and chronic harmaline administration on penicillin-induced epileptiform activity in rats.
- Author
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Ozkan, Kayhan and Demir, Serif
- Subjects
MONOAMINE oxidase inhibitors ,PEGANUM harmala ,PENICILLIN G ,ELECTROPHYSIOLOGY ,GLUTATHIONE peroxidase - Abstract
Copyright of Anatolian Clinic Journal of Medical Sciences is the property of Hayat Saglik ve Sosyal Hizmetler Vakfi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
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6. The Use of Propofol to Induce Anesthesia can Mitigate the Oxidative Stress Created by Laparoscopic Cholecystectomy, but not Thiopental.
- Author
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Çeliksu, Ayşe Gül, Aksoy, Şemsi Mustafa, Dumanli Özcan, Ayça Tuba, and Gokcinar, Derya
- Abstract
Aim: Laparoscopic cholecystectomy is one of the treatment methods employed in symptomatic cholelithiasis cases, and pneumoperitoneum has been shown to increase oxidative stress. Our aim is to compare propofol and thiopental in terms of their effects on oxidative stress parameters in laparoscopic cholecystectomy cases. Materials and Methods: After obtaining Ethics Committee permission, patients who underwent laparoscopic cholecystectomy were divided into thiopental and propofol groups according to the agent used for anesthesia induction in the randomized and prospective study. Serum oxidative stress parameters levels were measured in all patients twice before induction of general anesthesia and at the 30th minute postoperatively. Results: When comparing the preoperative period with the postoperative period, total antioxidant status (TAS) levels increased statistically significantly in the propofol group (preoperatively 1.21±0.21 mmolH2O2/L, postoperatively 1.31±0.18 mmolH2O2/L, p<0.001) compared to the thiopental group (preoperatively 1.23±0.14 mmolH2O2/L, postoperatively 1.27±0.14 mmolH2O2/L, p=0.055). arylesterase (ARES), serum native thiol, total thiol, and disulfide levels decreased statistically significantly in both groups. While Paraoxonase-1 (PON1) level did not change in the propofol group, it decreased in the thiopental group. Conclusion: We concluded that propofol had a significantly greater oxidative stress reduction effect than thiopental. By increasing the TAS levels, propofol may have a more positive effect on oxidative stress than thiopental. However, neither propofol nor thiopental have oxidative stressreducing effects on other oxidative stress parameters. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Determination of Serum Biochemical Profile and Oxidant-Antioxidant Activities in Damascus Goats at Different Ages
- Author
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Gamze Sevri Ekren Aşıcı, Süleyman Şensoy, and Hakan Tekeli
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antioksidanlar ,kan parametreleri ,şam keçisi ,yaş ,antioxidants ,age ,blood parameters ,damascus goats ,Veterinary medicine ,SF600-1100 - Abstract
This study aimed to research changes in biochemical profile and oxidant-antioxidant activities of Damascus goats of different ages. The 45 non-gravid Damascus goats of different ages were included in the research. They were divided into three groups of 15 goats according to age: goat kids ( - ≤ 6-months age), young goats (2-3-year age) and old goats (5-8-year age). Biochemical parameters and oxidant-antioxidant activities were determined in serum samples using commercial kits and colorimetric methods. The lowest serum urea, blood urea nitrogen, aspartate aminotransferase, total protein, albumin, globulin and magnesium levels were observed in goat kids (P < .05). Concentrations of glucose, inorganic phosphorus, non-esterified fatty acids, albumin/globulin and alanine aminotransferase decreased with age in the goats (P < .05). Serum total oxidant capacity, total antioxidants capacity and oxidative stress index levels were increased in goat kids compared to old goats (P < .05). Furthermore the highest serum glutathione and glutathione preoxidase activities were observed in young goats (P < .05). An increase was determined in concentrations of serum β-carotene and bilirubin in old goats compared to goat kids (P < .05). In contrast, serum catalase activity, arylesterase, ceruloplasmin and uric acid values did not differ between the groups. The results obtained on the biochemical profiles and oxidant-antioxidant activities of Damascus goats will contribute to monitoring this breed's age-related health and nutritional status and establishing reference values.
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- 2024
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8. Oksidatif Stres ve Kolorektal Kanser İlişkisinde Antioksidanların Önemli Rolü.
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Dusak, Zeynep Bozkoyun, Yaşar, Yusuf Ziya, and Şaprak, Ayşe
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SUPEROXIDE dismutase ,CARDIOVASCULAR diseases ,SEASONS ,COLORECTAL cancer ,OXIDATIVE stress ,CATALASE ,NEURODEGENERATION ,ANTIOXIDANTS ,FREE radicals ,GLUTATHIONE peroxidase ,KIDNEY diseases ,DIABETES - Abstract
Copyright of Van Health Sciences Journal / Van Sağlık Bilimleri Dergisi is the property of Van Yuzuncu Yil University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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9. Multifunctional polymer nanocomposite coated antibacterial filters for air-purification.
- Author
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Yontar, Arife Kübra, Yontar, Onur, and Çevik, Sinem
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POLYMERS , *NANOCOMPOSITE materials , *ANTIBACTERIAL agents , *POLYVINYL alcohol , *RAW materials - Abstract
Products used and produced in industrial locations must have natural ingredients and minimal energy usage due to air and environmental pollution. It is impossible for standard filters to clean bacterias in homes, workplaces and areas working with biological creatures. Therefore, the production of multifunctional nanocomposite and hybrid filter papers is necessary. In the study, filter papers coated with nanocomposite solutions prepared from green synthesized nanosilver (AgNPs) with plant extracts and Polyvinyl Alcohol (PVA). Scanning Electron Microscope (SEM) analyses showed that silver nanoparticles and PVA homogeneously coated the filter paper fibers, thereby reducing the average pore diameters by only 3% compared to commercial standards of filter paper. A filter with 36% higher burst pressure resistance was produced by nanosilver, plant extracts and PVA modification. The antibacterial effect is provided to the filters with a high effect of up to 10000 times, by coating them with nanosilver and plant extracts. This study made it possible to produce filter paper with natural ingredients and at low cost, reducing energy and raw material consumption, with high antibacterial effect and mechanical strength. In this way, bacteria and pollutants in the air will be cleaned without harming the environment and human health. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Potential Protective Role of Radicut in Valproic Acid-Induced Oxidative Stress in Rat Spleen.
- Author
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OKTAY, Nihal Şehkar, TÜZÜNER, Burçin ALEV, TUNALI, Sevim, ALTURFAN, Ebru EMEKLİ, AKBAY, Tuğba TUNALI, YANARDAĞ, Refiye, and YARAT, Ayşen
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OXIDATIVE stress ,VALPROIC acid ,SPLEEN ,ALKALINE phosphatase ,LIPID peroxidation (Biology) - Abstract
Copyright of Istanbul Gelisim University Journal of Health Sciences / İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi is the property of Istanbul Gelisim Universitesi Saglik Bilimleri Yuksekokulu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
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11. Determination of Serum Biochemical Profile and Oxidant-Antioxidant Activities in Damascus Goats at Different Ages.
- Author
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TEKELİ, Hakan, ŞENSOY, Süleyman, and EKREN AŞICI, Gamze Sevri
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ANTIOXIDANTS ,GOATS ,BLOOD urea nitrogen ,COLORIMETRIC analysis ,CERULOPLASMIN ,OXIDATIVE stress - Abstract
Copyright of Veterinary Sciences & Practices is the property of Ataturk University Coordinatorship of Scientific Journals and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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12. ANTIPROLIFERATIVE AND ANTIOXIDANT EFFECTS OF CARNOSIC ACID ON HUMAN LIVER CANCER CELLS.
- Author
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AKIN, Ugur Nuri, BAKIR, Elcin, HACISEYITOGLU, Aysun OKCESIZ, and EKEN, Ayse
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CARNOSIC acid ,ANTIOXIDANTS ,CANCER cells ,LIVER cancer ,MITOCHONDRIAL membranes ,CISPLATIN - Abstract
Copyright of Journal of Health Sciences / Sağlık Bilimleri Dergisi is the property of Erciyes Universitesi Saglik Bilimleri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
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13. Predictive effect of thiol/disulfide homeostasis dynamics on early pregnancy viability: A case-control study.
- Author
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Çendek, Büşra Demir, Aker, Seda Şahin, Dağdeviren, Gülşah, Alışık, Murat, Altay, Mehmet Metin, and Erel, Özcan
- Subjects
MISCARRIAGE ,RISK assessment ,STATISTICAL correlation ,HOMEOSTASIS ,DATA analysis ,ACADEMIC medical centers ,SULFUR compounds ,KRUSKAL-Wallis Test ,PREGNANCY outcomes ,DESCRIPTIVE statistics ,LONGITUDINAL method ,CASE-control method ,ONE-way analysis of variance ,STATISTICS ,RESEARCH ,DATA analysis software ,DISEASE risk factors ,PREGNANCY - Abstract
Objective: The main aim of this study was to investigate the differences in maternal serum thiol/disulfide homeostasis among women with abortion imminens (AI), missed abortion (MA), and healthy pregnancies during the first trimester. Materials and Methods: This was a prospective case-control study. This study was conducted on pregnant women who visited the Obstetrics Clinic at University of Health Sciences Turkey, Etlik Zübeyde Hanım Gynecology Training and Research Hospital and were diagnosed with either AI or MA during the 6th to 14th weeks of pregnancy. The participants had a normal pregnancy follow-up, no chronic illnesses, and did not take any multivitamin or antioxidant supplements except for folic acid. The study incorporated 33 pregnant women with AI, 36 with MA, and 40 with normal pregnancies. Age, and body mass index were matched across the three groups. This study used a recently developed automated spectrophotometric technique to quantify thiol/disulfide concentrations. Results: The AI group had considerably elevated levels of total thiol and native thiol (SH) compared with the MA group. Nevertheless, there was no notable disparity observed between the group of healthy pregnancies and the other two groups. Serum disulfide (SS) levels did not exhibit any significant variations among the three groups. Similarly, the ratios of SS/SH, SS/total thiol, and SH/total thiol did not show any significant differences between the groups (p>0.05). Conclusion: Patients with MA had decreased levels of total thiol and SH, which possess antioxidant capabilities, compared to the AI group. A decrease in antioxidant levels in the body may contribute to the etiology of MA. When considering our findings alongside existing literature, it remains inconclusive whether the serum thiol-disulfide ratio can predict a healthy pregnancy or MA following AI. Therefore, it is not yet seen as a promising diagnostic tool for assessing pregnancy viability. Additional investigation is required to establish the influence of dynamic thiol/disulfide homeostasis on early pregnancy loss. Amaç: Bu çalışmanın temel amacı, ilk trimester abortus imminens (AI), düşük ve sağlıklı gebeliği olan kadınlarda anne serumu tiyol/disülfit dengesindeki farklılıkları incelemektir. Gereç ve Yöntemler: Bu çalışma, Sağlık Bilimleri Üniversitesi, Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi Kadın Doğum Kliniği'ne başvuran, 6 ile 14. haftalar arasında AI veya düşük tanısı almış, normal gebelik süreci geçiren, kronik hastalığı bulunmayan ve folik asit dışında herhangi bir multivitamin veya antioksidan takviyesi kullanmayan hamile kadınları içeren prospektif bir çalışmadır. Çalışma, 33 AI, 36 düşük tanısı konmuş ve 40 normal gebelik olgusunu kapsamaktadır. Katılımcıların yaş, ve vücut kitle indeksi her üç grup arasında eşitlenmiştir. Tiyol/disülfit seviyeleri, yeni geliştirilmiş bir otomatik spektrofotometrik yöntemle ölçülmüştür. Bulgular: AI grubunda, düşük grubuna göre anlamlı derecede yüksek olan toplam tiyol ve doğal tiyol (SH) seviyeleri saptanmıştır. Ancak, sağlıklı gebelik gösteren grup ile diğer iki grup arasında belirgin bir fark bulunmamıştır. Serum disülfit (SS) düzeyleri üç grup arasında istatistiksel olarak anlamlı bir farklılık göstermemiştir. Ayrıca, SS/SH, SS/toplam tiyol ve SH/toplam tiyol oranları gruplar arasında önemli bir fark göstermemiştir (p>0,05). Sonuç: Düşük olgularında AI grubuna kıyasla düşük toplam tiyol ve SH seviyeleri gözlemlenmiştir; her ikisi de antioksidan özelliklere sahiptir. Vücuttaki antioksidan seviyelerindeki azalma, düşüğün etiyolojisine katkıda bulunabilir. Bulgularımızı mevcut literatürle birleştirdiğimizde, serum tiyol-disülfit oranının AI sonrasında sağlıklı bir gebeliği ya da düşüğü öngörüp öngöremeyeceği konusunda kesin bir sonuca varılamamıştır. Dolayısıyla, gebeliğin sağlıklı ilerleyip ilerlemeyeceğini değerlendirmede umut verici bir tanı aracı olarak görülmemektedir. Erken gebelik kaybında dinamik tiyol/disülfit homeostazının etkisini göstermek için ek araştırmalara ihtiyaç vardır. [ABSTRACT FROM AUTHOR]
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- 2024
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14. Effects of Deficit Irrigation to Some Bio - Active Compounds, Quality Traits and Grain Yield in Maize.
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ÖZDEMİR, Elif and SADE, Bayram
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DEFICIT irrigation , *GRAIN yields , *CORN , *HYBRID corn , *WATER shortages , *CROP science , *FARMERS - Abstract
As a result of environmental difficulties and water scarcity, maize production has been challenged in arid and semi - arid regions. A management strategy for stabilizing corn production under water shortage conditions involves the use of drought - tolerant hybrids and suitable irrigation regimes. The study was conducted in the Prof. Dr. Abdulkadir AKÇIN trial area of "Selcuk University, Agriculture Faculty, Crop Science Department, Konya, TÜRKİYE" during 2019 and 2020 growing seasons. The aim of the current work is determining the effects of deficit irrigation and grain colour factors on water shortage tolerance of maize in terms of bio - active compounds, quality traits and grain yield. The factors of the trial were irrigations [50% (I1), 75% (I2) and 100% (I3) of evaporation from Class A evaporation PAN] and genotypes [DKC 5783, red corn and Sakarya]. It was noted that DKC 5783 had the highest values at two (thousand grain weight, grain yield), Sakarya had at two (total phenolic compounds and grain crude oil) and red corn had at four (total anthocyanin content, total antioxidant activity, grain crude protein and starch) properties among eight under I1 during 2019 as well as red corn had at two (total anthocyanin content and total phenolic compounds), Sakarya had at two (grain crude protein and grain crude oil) and DKC 5783 had highest values at four (thousand grain weight, total antioxidant activity, starch and grain yield) features among eight under I1 during 2020. Thousand grain weight values of I3 were 6.71% and 0.57% more than I2 while starch was 9.19% and 3.96% more than I2 during 2019 - 2020. Red corn had better contents of bio - active compounds than other two varieties during both years of the trial. The mean yield of I3 was 6.87% more than I2 in 2019 and 9.05% more than I2 in 2020 which revealed that regulated deficit irrigation might help growers to cope with decline in water availability also 25% water restriction caused tolerable decreases in grain yield and some yield compounds of the current work. [ABSTRACT FROM AUTHOR]
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- 2024
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15. Investigation of the Oxidative Process by Measuring Total Antioxidant Capacity and Total Oxidant Capacity in Patients with Mucopolysaccharidosis: Cross-Sectional Prospective Study.
- Author
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KALKAN, Eylem Şerife, YAVAŞ, Aynur KÜÇÜKÇONGAR, UZUN, Özlem ÜNAL, and GÜNDÜZ, Mehmet
- Abstract
Objective: To compare the oxidative stress status between the patients with mucopolysaccharidosis who received and did not receive enzyme replacement therapy and healthy control group. Material and Methods: A retrospective study of mucopolysaccharidosis patients with analysis of the total oxidant and antioxidant capacity levels. Results: We included 29 mucopolysaccharidosis patients aged between 1-18 years and 50 healthy children. Total antioxidant capacity and total oxidant capacity parameters between this patients and healthy control group were compared. The median age of the patients who were included in the study was 9.0 years and the median age of the cases included in the control group was 8.0 years. Total antioxidant capacity, total oxidant capacity and Oxidative Stress Index (OSI) values did not differ significantly in patients receiving enzyme replacement therapy compared to patients who did not receive enzyme replacement therapy. A comparison of the oxidant and antioxidant system parameters between the patient and control groups revealed a distinct difference, with the control group exhibiting a considerably higher total antioxidant capacity than mucopolysaccharidosis patients, and the patient group showing a significantly higher total oxidant capacity and OSI. Conclusion: In this study, it was observed that the antioxidant defence system decreased in patients with mucopolysaccharidoses. It is thought that, in addition to standard treatments, the administration of antioxidant treatments and supporting nutrition in mucopolysaccharidosis patients will increase the quality of life of the patients. Regular sleep, eating healthy foods and doing regular exercise would also increase the effectiveness of these supplements [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
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16. The effect of six days open water swimming activity on salivary, oxidative stress and cortisol levels on elite master swimmers.
- Author
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OKTAY, Nihal Şehkar, ÇİMEN, Kubilay, TACAL ASLAN, Beste, ÇALIŞKAN, Şükriye, KARAGÖZOĞLU, Cengiz, and ULUCAN, Korkut
- Abstract
Copyright of Journal of ROL Sport Sciences / ROL Spor Bilimleri Dergisi is the property of Journal of ROL Sport Sciences / ROL Spor Bilimleri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
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17. Investigation of Effects of Local Vitamin C Application on Inflammatory Response and Periodontal Tissue Destruction in Rat Periodontitis Model
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Kübra Karaçam, Ayşe Toraman, and Zeliha Aytekin
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antioxidants ,experimental periodontitis ,oxidative stress ,vitamin c ,antioksidanlar ,deneysel periodontitis ,oksidatif stres ,Dentistry ,RK1-715 - Abstract
Background: The present study aims to evaluate the effect of local vitamin C application on inflammatory response and periodontal tissue destruction in rats with experimental periodontitis. Methods: A total of 21 animals, 7 rats in each group, were used in the study: 1- Non-ligation (NL), 2-experimental periodontitis (EP), and 3- local vitamin C (VtC) groups. Experimental periodontitis was induced in EP and VtC group rats. After 11 days, the ligature was removed. 50 mL of saline solution and vitamin C were injected locally into the vestibule sulcus of the EP and VtC group rats, respectively. After the rats were sacrificed, blood and gingival tissue samples were taken. TNF-α levels were analyzed biochemically in serum and 8-OHdG and MMP-8 were analyzed immunohistochemically in gingival tissue. The mandibular specimens were histologically evaluated for bone destruction and attachment loss. Results: The numeric density of 8-OHdG and MMP-8 immunopositive cells were found to be statistically significantly lower in the Vtc group than in the EP group. Vitamin C administration significantly reduced attachment loss and bone loss in the VtC group as compared to the EP group. However, there was no significant difference in serum TNF-α level in the VtC group compared to the EP group. Conclusions: Local application of vitamin C may reduce inflammation-related bone destruction by supporting the inflammatory response with the antioxidant activity of vitamin C and contributing to the resolution of inflammation with its potential immunomodulatory effect. Vitamin C may be a therapeutic agent that can be used in the treatment of periodontitis.
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- 2023
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18. Tuz Stresinin Bitkiler Üzerindeki Etkileri ve Geliştirilen Tolerans Mekanizmaları
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Büşra Sevgi and Sema Leblebici
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abiyotik stres ,tuzluluk ,ozmolitler ,antioksidanlar ,moleküler yanıtlar ,abiotic stress ,salinity ,osmolytes ,antioxidants ,molecular responses ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Science ,Science (General) ,Q1-390 - Abstract
Jeolojik, hidrolojik ve antropojenik birçok faktörün neden olduğu tuz stresi, bitkilerin hemen hemen tüm gelişme dönemlerinde olumsuz etkilere sebep olan oldukça karmaşık bir abiyotik strestir. Tuz stresinin neden olduğu ozmotik stres, bitki hücresindeki iyonik dengeyi ve genel homeostazı bozar. Bu abiyotik stres, osmotik strese neden olarak bitkilerin kullanabileceği su miktarını kısıtladığı gibi, iyonik stresi de tetikleyerek bitkilerde iyon miktarının toksik seviyelere ulaşmasına neden olmaktadır. Ayrıca bitkilerde reaktif oksijen türlerinin (ROT) artışını tetikleyen ikincil bir oksidatif stres oluşumuna neden olmaktadır. Genel olarak tuz stresine maruz kalan bitkilerde turgor kaybı, stoma iletkenliği ve fotosentez hızında azalma, besin dengesizliği, biyokütlenin azalması ve büyümenin yavaşlaması yaygın etkiler arasında görülür. Bitkiler bu olumsuz etkilerle baş edebilmek ve tuza tolerans oluşturabilmek için tuz alımı ve iyon taşınmasının kontrolü, ozmolitlerin ve antioksidanların sentezi veya birikimini içeren çeşitli savunma mekanizmaları geliştirmişlerdir. Farklı bitkiler, genotipe, adaptasyon kabiliyetine ve bitkinin diğer özelliklerine bağlı olarak tuzluluğa farklı tepkiler vermektedir. Endüstrileşmenin ve insan faaliyetlerinin hızla arttığı küreselleşen dünyada tuzluluğa dayanıklı transgenik bitkilerin geliştirilmesi verimliliği ve ürün kalitesi daha yüksek bitkiler elde etmek için oldukça önemlidir. Yüksek tuz konsantrasyonlarında yaşamlarını sürdürebilen halofitler ise, istenilen gen kaynağının sağlaması açısından tuza toleranslı glikofit bitkilerin yetiştirildiği çoğu transgenik çalışmada model organizmalar olarak kullanılmaktadır.
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- 2023
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19. Besinlerde melanoidinlerin oluşumu ve sağlık üzerine etkileri.
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KARAGÖL, Gülbin and RAKICIOĞLU, Neslişah
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AMINO acid metabolism ,PROTEIN metabolism ,ANTIHYPERTENSIVE agents ,APPETITE ,DIETARY fiber ,BREAD ,PREBIOTICS ,GUT microbiome ,FOOD consumption ,MONOSACCHARIDES ,ANTIOXIDANTS ,ANTI-infective agents ,FOOD handling ,CARBOHYDRATES ,XENOBIOTICS - Abstract
Copyright of Food & Health (2602-2834) is the property of Scientific Web Journals (SWJ) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
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20. The Potential Antioxidant Effects Of Ziziphus Jujube On Melanoma Cells.
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KÜÇÜKGÜL, Altuğ, DÜZGÜNER, Vesile, İŞGÖR, Mehmet Mustafa, KIZILKAYA, Pınar, and CELLAT, Mustafa
- Subjects
- *
JUJUBE (Plant) , *ZIZIPHUS , *OXIDANT status , *MELANOMA , *REACTIVE oxygen species - Abstract
Cellular redox homeostasis is compromised when exposed to internal or external stress factors, resulting in the superiority of the oxidant. It is known that these reactive oxygen species play a critical role in the etiology of many serious diseases like diabetes and cancer. Melanoma is the deadliest form of skin cancer and its rates are currently increasing faster than other preventable cancers. Melanoma is caused by the appearance of genetic mutations in pigment-producing cells, melanocytes. Ziziphus jujube Mill. spreads in regions of Asia with tropical/subtropical climates and has been used for thnds of years as basic traditional folk medicine. This study was carried out to determine the potential antioxidant effects of Ziziphus jujube on melanoma. Survival of cells was measured by MTT assay (colorimetric). Melanoma cells were treated three hours with 100% concentration Ziziphus jujube essential oil. Total antioxidant and oxidant capacity, glutathione, and nitric oxide levels were determined by spectrophotometrically. Ziziphus jujube prevented cell proliferation and increased total antioxidant capacity. Our results indicated that Ziziphus jujube inhibited the decrease in antioxidant levels and elevation of nitric oxide levels in melanoma cells. Also, the Ziziphus jujube administration improved GSH levels. Briefly, it can be concluded that Ziziphus jujube showed potential antioxidative and antiproliferative effects in melanoma cells. Recent research provides a detailed ethnopharmacological approach for the medicinal use of Ziziphus jujube fruit. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
21. Effect of Dose-Related Astaxanthin on Rats with Cerebral Ischemia-Reperfusion.
- Author
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Yegin, Bengi, Oz, Semih, Donmez, Dilek Burukoglu, Ozden, Hilmi, Ustuner, Cengiz, Kabay, Sibel Canbaz, and Yucel, Ferruh
- Subjects
ASTAXANTHIN ,BRAIN damage ,FREE radicals ,CEREBRAL cortex ,DIMETHYL sulfoxide ,MYOCARDIAL reperfusion - Abstract
Copyright of Journal of Health Science Yuksek Ihtisas University / Yüksek İhtisas Üniversitesi Sağlık Bilimleri Dergisi is the property of Journal of Health Science Yuksek Ihtisas University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
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22. Tuz Stresinin Bitkiler Üzerindeki Etkileri ve Geliştirilen Tolerans Mekanizmaları.
- Author
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SEVGİ, Büşra and LEBLEBİCİ, Sema
- Abstract
Copyright of Duzce University Journal of Science & Technology is the property of Duzce University Journal of Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
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23. Otoprotective effects of farnesene against oxidative damage induced by paclitaxel
- Author
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Arzu Tatar, Fatma Atalay, and Büşra Dincer
- Subjects
antioksidanlar ,farnesen ,otoakustik emisyon ,ototoksisite ,paklitaksel ,antioxidants ,farnesene ,otoacoustic emission ,ototoxicity ,paclitaxel ,Medicine (General) ,R5-920 - Abstract
Purpose: This study explores the biochemical and functional effects of farnesene, which has potent free radical scavenging and antioxidant properties, on paclitaxel-induced ototoxicity. Materials and Methods: Eighteen male Wistar albino rats were allocated into three groups of six rats at random. No paclitaxel or farnesene was given to the control group throughout the research. Paclitaxel was given four times intraperitoneally at a dose of 5 mg/kg (1st, 7th, 14th & 21st days) in the paclitaxel group. In the Farnesene + Paclitaxel group, 5 mg/kg paclitaxel was given first, followed by 4 times 50 mg/kg farnesene intraperitoneally 30 minutes later (1st, 7th, 14th & 21st days). Otoacoustic emission measurement was taken on days 0 and 21 in all rats. After that, the animals were sacrificed, and their cochleas were extracted for biochemical testing. Results: Paclitaxel caused oxidative stress in the cochlea, which considerably elevated malondialdehyde levels and lowered glutathione levels in cochlear tissues. Furthermore, the paclitaxel group’s distortion product otoacoustic emission values were significantly lower than the other groups. Improvements in the damage produced by paclitaxel in various biochemical and functional parameters were observed in the Farnesene+Paclitaxel group. Conclusion: The study findings imply that farnesene, a natural antioxidant, reduced paclitaxel-induced hearing loss in rats, and a combination of farnesene and paclitaxel therapy may have protected from paclitaxel-induced ototoxicity for future clinical use.
- Published
- 2022
- Full Text
- View/download PDF
24. Characterization of White, Yellow, Red, And Purple Colored Corns (Zea Mays İndentata L.) According to Bio - Active Compounds and Quality Traits.
- Author
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ÖZDEMİR, Elif, CENGİZ, Rahime, and SADE, Bayram
- Subjects
BIOACTIVE compounds ,PHENOLS ,CAROTENOIDS ,ANTIOXIDANTS ,ANTHOCYANINS - Abstract
Copyright of Anadolu Tarım Bilimleri Dergisi is the property of Ondokuz Mayis Universitesi, Ziraat Fakultesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
25. Gökkuşağı Alabalığı (Oncorhynchus mykiss, w.)'nda Arı Poleninin Bazı İmmünolojik Parametrelere Etkisi.
- Author
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YÖNTÜRK, Yassir and YONAR, M. Enis
- Subjects
RAINBOW trout ,BEE pollen ,RADICALS (Chemistry) ,BLOOD sampling ,POLLEN ,HEMATOCRIT ,POLLINATION - Abstract
Copyright of Firat Universitesi Saglik Bilimleri Veteriner Dergisi is the property of Firat Universitesiu, Saglik Bilimleri Enstitusu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
26. Sous vide ve geleneksel pişirme yöntemlerinin kabak ve yeşil fasulyenin renk özellikleri ve antioksidan kapasitesine etkisinin karşılaştırılması.
- Author
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YILMAZ, Sena Nur and İLYASOĞLU, Huri
- Subjects
VEGETABLES ,LEGUMES ,PHENOLS ,IRON ,ANTIOXIDANTS ,COOKING ,IRON in the body ,STEAM - Abstract
Copyright of Food & Health (2602-2834) is the property of Scientific Web Journals (SWJ) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
27. Farklı su sıcaklıklarındaki pullu sazan (Cyprinus carpio Linnaeus, 1758)’ da polenin antioksidan etkisinin araştırılması.
- Author
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Taşkan, Merve and Yonar, Muhammet Enis
- Subjects
OXIDANT status ,TEMPERATURE control ,BEE pollen ,WATER temperature ,CARP - Abstract
Copyright of Ege Journal of Fisheries & Aquatic Sciences (EgeJFAS) / Su Ürünleri Dergisi is the property of Ege Journal of Fisheries & Aquatic Sciences (EgeJFAS) / Su Urunleri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
28. Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase.
- Author
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Gul, Pinar, Karatas, Ozcan, Sagsoz, Omer, Askın, Seda, Turkerı, Ozge, and Kızıltunc, Ahmet
- Subjects
METALLOTHIONEIN ,SUPEROXIDE dismutase ,DENTAL fillings ,INDUCTIVELY coupled plasma mass spectrometry ,ANTIOXIDANTS ,BLOOD sampling - Abstract
Copyright of European Oral Research is the property of Istanbul University, Faculty of Dentistry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
29. Determination of Oxidative Stress and Antioxidant Activities in Dogs Infected with Canine Distemper Virus.
- Author
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HATİPOĞLU, Durmuş, DİK, Irmak, and GÜLERSOY, Erdem
- Subjects
- *
CANINE distemper virus , *LIPID peroxidation (Biology) , *DOG breeds , *OXIDATIVE stress , *DOGS , *ENZYME-linked immunosorbent assay , *REACTIVE oxygen species - Abstract
Supraphysiological reactive oxygen species (ROS) has been linked to a variety of diseases, including cancer, inflammation, and neurodegeneration. One of the diseases pathophysiologically associated with ROS accumulation is canine distemper (CD). The purpose of this study was to compare lipid peroxidation and antioxidant biomarkers in dogs infected with canine distemper virus (CDV) to healthy dogs. The animals in this study consisted of a total of 20 dogs, 10 CDV-positive dogs (Trial group) aged 0-12 months of different breeds and sexes, and 10 healthy dogs (Control group) aged 0-12 months of different breeds and sexes. Thiobarbituric acid reactive substances (TBARS), glutathione (GSH) and superoxide dismutase (SOD) were evaluated with commercially available enzyme-linked immunosorbent assay kits using serum samples. While the activities of GSH and SOD were statistically lower in CDV positive animals compared to healthy animals (p<0.05), the level of TBARS was significantly higher (p<0.05). In conclusion, current study findings that CDV increases lipid peroxidation activity in serum while decreasing antioxidant enzyme levels may be useful for future research. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
30. Potential effects of punicalagin on New Zealand White rabbits exposed to bisphenol A.
- Author
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YILDIZ GÜLAY, Özlem, CANDAN, Gülşah, and GÜLAY, Mehmet Şükrü
- Subjects
RABBITS ,BISPHENOL A ,ANTIOXIDANTS ,MALONDIALDEHYDE - Abstract
Copyright of Kocatepe Veterinary Journal / Kocatepe Veteriner Dergisi is the property of Afyon Kocatepe University, Faculty of Veterinary Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
31. Diyabetik Makula Ödemi ile Diyet İleri Glikasyon Son Ürünleri (AGEs) ve Oksidatif Stres Arasındaki İlişkinin Değerlendirilmesi
- Author
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Gülhan Samur, Sibel Kadayıfçılar, Dila Kırağı, and Sedat Arslan
- Subjects
maküla ödemi ,diyabet komplikasyonları ,i̇leri glikasyon son ürünleri ,beslenme ,antioksidanlar ,Medicine (General) ,R5-920 - Abstract
Giriş: Diyabetik makula ödemi (DMÖ), görme bozukluklarına ve körlüğe sebep olan bir hastalıktır. Kötü yönetilen diyabetin, retinopati komplikasyonu riski yüksektir. Diyetle glisemik kontrolü iyileştirmenin, diyabetik retinopatinin önlenmesinde etkili olduğu belirtilmiştir. Amaç: Bu çalışma, serum ileri glikasyon son ürünleri (AGEs), ileri glikasyon son ürünleri reseptörü (sRAGE) ve bireylerin diyet AGE (dAGE) alımları ile DMÖ hastalığı arasındaki ilişkiyi incelemek amacıyla yapılmıştır. Yöntem: Hacettepe Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı’nda takip edilen DMÖ tanısı alan ve almayan toplam 90 diyabetli bireyin katılımıyla yapılmıştır. Bireylerin serumunda toplam antioksidan seviye (TAS), toplam oksidan seviye (TOS) ve ELISA yöntemiyle AGEs (karboksimetil lizin (CML)), sRAGE düzeyleri analiz edilmiştir. Ayrıca bireylerin besin tüketim kayıtları alınarak diyet AGEs alımı ve diyet glisemik indeksi/yükü hesaplanmıştır. Bulgular: DMÖ grubunun yaş ortalaması 62.6±8.4 ve kontrol grubunun yaş ortalaması 58.7±7.8 olarak belirlenmiştir. DMÖ grubunun AGEs düzeyleri ve diyet AGEs alımları kontrol grubuna göre istatistiksel olarak anlamlı düzeyde yüksek bulunmuştur (p0,05). Vaka grubunun TOS değerleri ve oksidatif stres indeksi (OSİ) ortalamaları kontrol grubuna göre istatistiksel olarak anlamlı düzeyde yüksek bulunmuştur (p0.05). Vaka grubunda serum AGE ve sRAGE düzeyleri arasında pozitif yönde orta derecede korelasyon (p
- Published
- 2021
- Full Text
- View/download PDF
32. Effects of Acupuncture on Cholesterol, Antioxidant and Oxidant Parameters in Obese Women: Clinical Trials.
- Author
-
MİT, Şebnem Setenay, SEVERCAN, Çınar, GEÇİOĞLU, Ersel, SİVRİ, Ayşe Banu ÇAYCI, YILMAZ, Canan, GÜÇEL, Funda, and ÇEVİK, Cemal
- Subjects
ACUPUNCTURE ,CHOLESTEROL ,ANTIOXIDANTS ,OVERWEIGHT women ,CLINICAL trials - Abstract
Objective: Obesity has a profound adverse impact on health care systems. Acupuncture has been shown to have beneficial effects on obesity. The aim of this study is to investigate the effects of acupuncture on serum oxidative stress parameters in obese women. Material and Methods: During the study, 20 obese patients had acupuncture treatment, and as a control group, 20 obese patients had sham acupuncture treatment. Serum samples were taken from each patient before the first session and at the end of the 10th session and serum levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol, malondialdehyde (MDA), advanced oxidation protein products (AOPP), the serum activity of superoxide dismutase enzyme (SOD) and glutathione peroxidase enzyme (GPx) were measured. Results: Changes in the serum levels of TG, HDL, MDA, AOPP and activity of SOD after the treatment compared to before the treatment in both acupuncture and sham acupuncture treated groups were found insignificant (p>0.05). On the other hand, the TC and LDL levels were observed to decrease significantly in comparison to the before-treatment values in both the acupuncture and sham acupuncture groups (p<0.05). In addition to this, the GPx activity significantly increased only as a result of the acupuncture treatment (p<0.05). Conclusion: The results of our study indicated that acupuncture treatment may be effective in reducing cholesterol levels and increasing the activity of antioxidant enzymes. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
33. Otoprotective effects of farnesene against oxidative damage induced by paclitaxel.
- Author
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Dincer, Büşra, Atalay, Fatma, and Tatar, Arzu
- Subjects
PACLITAXEL ,OTOACOUSTIC emissions ,PRESBYCUSIS ,CONTROL groups ,AUDITORY neuropathy ,LABORATORY rats - Abstract
Copyright of Cukurova Medical Journal / Çukurova Üniversitesi Tip Fakültesi Dergisi is the property of Cukurova University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
34. The efficiency of oxerutin on apoptosis and kidney function in rats with renal ischemia reperfusion injury.
- Author
-
Güzel, Ahmet, Özorak, Alper, Oksay, Taylan, Öztürk, Sefa Alperen, Bozkurt, Kemal Kürşat, Yunusoğlu, Sedat, Uz, Efkan, Uğuz, Abdulhadi Cihangir, and Koşar, Pınar Aslan
- Subjects
ISCHEMIA ,FLAVONOIDS ,BLOOD urea nitrogen ,CYSTATINS ,ANIMAL experimentation ,RENAL artery ,APOPTOSIS ,ANTIOXIDANTS ,KIDNEY diseases ,RATS ,OXIDATIVE stress ,REPERFUSION injury ,CREATININE ,BLOOD - Abstract
Copyright of Turkish Journal of Trauma & Emergency Surgery / Ulusal Travma ve Acil Cerrahi Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
35. Thiols and Their Uses in the Food Industry
- Author
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İnci Cerit, Aslı Demirer, Eda Bülbül, Merve Yaman, Şeyma Nur Güngör, and Omca Demirkol
- Subjects
antioksidanlar ,tiyoller ,katkı maddeleri ,glutatyon ,oksidatif stres ,Agriculture ,Agriculture (General) ,S1-972 - Abstract
Studies have shown that many of the synthetic additives which are added to food for different purposes have negative impacts on human health. For this reason, researchers have focused on natural additives that can replace with synthetic ones and positively affect health through their various functions. Biothiols have effects on color, taste and aroma in foods. In addition, they possess various functions in the prevention of cancer, Alzheimer's, Parkinson's, lung and heart diseases by decreasing oxidative damage with their antioxidant and protective effects. In this review, the studies about thiol contents of food, their functions and the possibilities of using thiols in the food industry instead of synthetic additives have been brought together.
- Published
- 2020
- Full Text
- View/download PDF
36. GC/FID ile ekstrakte edilen Ferula elaeochytris kök ekstresinden yağ asidlerinin analizi
- Author
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Ferudun Koçer, Nadire Eser, and Atila Yoldaş
- Subjects
yağ asitleri ,kromotografi ,antioksidanlar ,gc/fid ,Medicine - Published
- 2020
- Full Text
- View/download PDF
37. Ameliorative Potential of Rosuvastatin on Doxorubicin-induced Cardiotoxicity by Modulating Oxidative Damage in Rats.
- Author
-
RAJANGAM, Jayaraman, KRISHNAN S., Navaneetha, PALEI, Narahari N., BHATT, Shvetank, DAS, Manas Kumar, DAS, Saumya, and MATHUSOOTHANAN, Krishnapillai
- Subjects
- *
DOXORUBICIN , *ASPARTATE aminotransferase , *LIVER enzymes , *ROSUVASTATIN , *HEMATOXYLIN & eosin staining , *CARDIOTOXICITY , *LACTATE dehydrogenase - Abstract
Objectives: The study aimed to explore the in vivo protective potential of rosuvastatin (ROSS), an oral antihyperlipidemic drug against doxorubicin (DOXO) induced cardio toxicity in rats. Materials and Methods: Cardiac toxicity was induced by DOXO injection (10 mg/kg, i.p.), once on the 20th day of the experiment. Except for the control rats, all were received DOXO and the study was continued for up to 21 days. The influence of ROSS on acute treatment was analyzed by quantification of cardiac marker enzymes such as creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH) and liver marker enzymes like aspartate aminotransferase (AST), alanine aminotransferase (ALT) along with the measurement of in vivo antioxidants like superoxide dismutase and catalase. To observe histological changes of myocardial tissue hematoxylin and eosin staining were used. Results: Acute administration of DOXO resulted in a marked rise of cardiac marker enzymes that confirms the myocardial damage compared to control animals whereas administration of ROSS (10 mg/kg, p.o.) resulted in the significant reduction of CK-MB, LDH levels (p<0.05) and AST, ALT levels to a remarkable extent. Moreover, ROSS administration significantly increased the activities of various in vivo antioxidant levels. Conclusion: From the results, the acute administration of ROSS showed significant cardioprotective property, which was evidenced by a significant reduction of cardiac and liver marker enzymes along with significant improvement of in vivo antioxidant activities. Furthermore the results were supported with histopathological observations. Hence, it can be concluded that cardioprotective potential of ROSS may be through attenuation of oxidative stress by modulating oxidative damage in rats. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
38. A Traditional Review of the Role of Nutrition in the Autism Spectrum Disorder.
- Author
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ÇITAR DAZIROĞLU, Merve Esra, SAĞDIÇOĞLU CELEP, Adviye Gülçin, and ÖZTÜRK, Cansu
- Subjects
NUTRITION ,AUTISM spectrum disorders ,FOOD allergy ,OMEGA-3 fatty acids ,ANTIOXIDANTS - Abstract
Copyright of Turkiye Klinikleri Journal of Health Sciences / Türkiye Klinikleri Sağlık Bilimleri Dergisi is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
39. A Review on the Bioactive, Antioxidant Properties of Einkorn (Triticum monococcum L. ssp. monococcum) Populations and Using in Organic Agriculture
- Author
-
Alaettin Keçeli
- Subjects
siyez ,organik tarım ,antioksidanlar ,biyoaktif bileşenler ,i̇nsan sağlığı ,Agriculture ,Agriculture (General) ,S1-972 - Abstract
In addition to having the most cultivation area and production in the world, cereals are irreplaceable in agriculture and in our life with being a basic food material. Wheat, which ranks first in terms of sowing area, is also an origin of our country and has been a basic food raw material since the beginning of history. Besides, wheat contains starch, protein, phytochemical and antioxidant substances which have an important role in human nutrition. As agricultural fertilizers, pesticides and herbicides have negative effects on the environment and human health, the interest in organic agriculture is increasing. The suspicion that pesticide, synthetic fertilizer and growth regulator residues can lead to cancer and other health problems in humans has led the researchers to focus their attention to improve of production methods that will prevent these disadvantages. Research has shown that the most reliable method of production is called Organic or Ecological or Biological Agriculture method. For these reasons, organic agriculture practices in the world have increased in the last 15 years. New breeding varieties selected in high-yielding traditional farming conditions do not sufficiently adapt to organic farming conditions. Readily available existing varieties due to yet correspond to new breeding for organic farming conditions not only yield when used in organic farming but also that they contain proteins and other useful in amounts of vitamins components also occurs a decrease. Cultivation of local varieties is becoming more attractive instead of already cultivated in marginal areas and stable yield values. For this purpose, local varieties produced in restricted regions of our country are the most suitable candidates for both breeding and organic production since they are well adapted to the regions where they are located.
- Published
- 2019
- Full Text
- View/download PDF
40. The effects of ozone therapy on extremity ischemia-reperfusion injury in a rabbit model
- Author
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Ganime Coban, Burak Kaymaz, Umut Hatay Golge, Ferdi Goksel, Erkam Komurcu, and Huseyin Toman
- Subjects
rabbits ,ozone ,femoral artery ,reperfusion injury ,ischemia ,antioxidants ,tavşanlar ,ozon ,femoral arter ,reperfüzyon hasarı ,iskemi ,antioksidanlar ,Public aspects of medicine ,RA1-1270 - Abstract
Introduction: Ischemia is reversible orirreversible cell/tissue damage that is secondary to insufficient blood flow totissues or organs. Ischemia causes many metabolic and structural changes at thecellular level. Ozone therapy is often used as an antioxidant remedy. Thisstudy aimed to investigate the effects of ozone therapy on extremityischemia-reperfusion (IR) injury.Methods: Twenty-four New ZealandWhite (NZW) rabbits were randomly allocated into three groups. Each groupconsisted of eight rabbits. Group I was the control group, Group II was theischemia group, and Group III, the ozone group.Femoral arteries of the right legs were dissected, and femoral arterialocclusion was performed in Group II and III.Hematological and histopathological evaluation was performed in allgroups.Results: The levels of totalantioxidant status (TAS) after the surgical procedure was higher in the ozonegroup compared to the ischemia group (p=0.036). In addition, the levels ofmalondialdehyde (MDA) after the surgical procedure were lower in the ozonegroup compared to the ischemia group but not statistically significant(p=0.093). The control and ozone groups were histopathologically similar.Conclusions: Ozone therapy may be usedas an alternative treatment modality with its anti-inflammatory and antioxidanteffects for the treatment of extremity IR injury.
- Published
- 2019
- Full Text
- View/download PDF
41. VITAMIN D DEFICIENCY DID NOT AUGMENT THE PROGRESSION OF HIGH-FRUCTOSE-INDUCED NONALCOHOLIC FATTY LIVER DISEASE IN RATS.
- Author
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BİNGÜL, İlknur, KÜÇÜKGERGİN, Canan, AYDIN, Abdurrahman Fatih, DOĞAN EKİCİ, Işın, DOĞRU ABBASOĞLU, Semra, and UYSAL, Müjdat
- Subjects
- *
NON-alcoholic fatty liver disease , *VITAMIN D deficiency , *RAT diseases , *FATTY liver , *LABORATORY rats - Abstract
Objective: Vitamin D has antioxidant, anti-inflammatory and antiglycation activities, and hepatoprotective potential. There is a relationship between vitamin D deficiency (VDD) and the severity of liver disorders. VDD has been proposed to contribute to the progression of nonalcoholic fatty liver disease (NAFLD). However, experimental results are not clear. Therefore, in this study, the effects of a VDD diet on high fructose (HFr) drinking-induced NAFLD was evaluated. Material and Method: Male Wistar rats were divided into four groups as control, HFr, VDD+HFr, and VDD. Control and HFr groups were fed a control diet, and other groups with a VDD-diet for 12 weeks. HFr (30%; w/v; in drinking water) was given in the last 8 weeks. Insulin resistance (IR), serum lipids, hepatic triglyceride, lipid peroxide, protein carbonyl, advanced glycation end products (AGEs) and inflammation (TNF-α and myeloperoxidase) parameters, and histopathological changes were investigated. Results: Increases in serum transaminases, hypertriglyceridemia, and IR were observed in HFr and VDD+HFr groups. Increased liver triglyceride, lipid and protein oxidation products, protein glycation and inflammation markers as well as microvesicular hepatic steatosis and hepatocyte ballooning were observed in both groups. Although IR and hepatic inflammation markers were higher in the VDD+HFr group, serum transaminases, hepatic triglyceride, lipid and protein oxidation products, and glycation indicators in the liver did not alter between the two groups. However, Nrf2 mRNA expression and superoxide dismutase and glutathione peroxidase mRNA expression and activities were significantly higher in the VDD+HFr group. Conclusion: Our results show that VDD did not augmented HFr-induced hepatotoxicity and glycooxidative stress in the liver of rats. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
42. Lead and Cadmium Induced Oxidative Stress in the Epididymis and Spleen of Rats: Effects of Sesamol.
- Author
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APAYDIN, Fatma Gökçe, BAŞ, Hatice, and KALENDER, Yusuf
- Subjects
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LEAVES , *CADMIUM , *OXIDATIVE stress , *EPIDIDYMIS , *POLLUTANTS - Abstract
Lead and cadmium are known as environmental pollutants extensively found in food and water that induce hazards to animals' and people's health. Sesamol is a dietary antioxidant that is found in some plants. Epididymis is known to play an important role in the maturation and storage of the sperm. The spleen is an important organ involved in the immune response. The present study aims to analyze the oxidative stress in spleen and epididymis. Therefore, Lead (LN) (90 mg/kg bw per day, 1/25 LD50), Cadmium (CdCl2) (3 mg/kg bw per day, 1/25 LD50), and sesamol (50 mg/kg bw per day) were given to rats by gavage for 28 days. Antioxidant enzyme activities in epididymis and spleen tissues [superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione S transferase], malondialdehyde (MDA) were investigated at the end of 28 days comparatively with the control group. It is revealed that there is a significant decline in the antioxidant enzymes and increase in MDA levels in the spleen and epididymis tissues of the lead and cadmium treated rats compared to the control group. A small increase in these parameters was also observed in the sesamol treated groups. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
43. İnsülin-dirençli Memeli Kalp Fonksiyon Bozukluğunda Mitokondrihedefli Antioksidan Mitotempo Uygulamasının Pozitif Etkileri.
- Author
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Bitirim, Ceylan Verda, Olgar, Yusuf, Billur, Deniz, Akçalı, Kamil, and Turan, Belma
- Abstract
Copyright of Journal of Ankara University Faculty of Medicine / Ankara Üniversitesi Tip Fakültesi Mecmuasi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
44. Solanum Fruit Juice as a Natural and Sustainable Source of Antioxidants for Patients with Chronic Hepatitis C under Antiviral Therapy.
- Author
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Iheka, Chidiebere Uchenna, Osuoha, Justice Obinna, Archibong, Idongesit Ekong, Amadi, Peter Uchenna, and Adeoti, Oluwatoyin Taiwo
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FRUIT juices , *CHRONIC hepatitis C , *SOLANUM , *ADIPOSE tissues , *HEPATITIS C virus - Abstract
Variations in liver metabolism as a result of hepatitis C virus have been established by numerous clinical trials. The use of antioxidants supplements has been reported to minimize the implication of this disease. In this regard, we examined the suitability of Solanum fruit juice, a natural source of vitamin C and citrus flavoniod as a precursor for the treatment of patients with chronic hepatitis C. Forty adult patients who were diagnosed with chronic hepatitis C and were under antiviral therapy were divided into two equal groups. Group 1 patients received their antiviral therapy with normal food and water and served as the control group while patients in group 2 were supplemented with Solanum fruit juice for eight consecutive weeks. Measurements for Anthropometric data, C reactive protein (CRP), atherogenic indices, biochemical parameters and activities of liver marker enzymes were recorded before and after eight weeks. No alterations were found in waist circumference, body mass and body fat following regular use of Solanum fruit juice. The serum levels of oxidative stress markers, LDL-cholesterol, total cholesterol, CRP and atherogenic indices decreased in the Solanum fruit juice group when compared to the control group. Moreover, the activities of the liver marker enzyme AST decreased in those who had high levels before the intervention. These results underscore the benefits of Solanum fruit juice in the diet of patients with HCV as a result of decreased cholesterol in blood serum, decreased inflammation, and increase in antioxidant capacity as well as maintaining body mass index. This clinical trial is registered at Pan African Clinical Trial Registry (www.pactr.org) with unique identification number PACTR201802003092138. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
45. Comparative Seed Morphology, Pharmacognostic, Phytochemical, and Antioxidant Potential of Memecylon L. Fruits.
- Author
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SREE, P. R. RAMYA and THOPPIL, J. E.
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PHYTOCHEMICALS , *COMPARATIVE anatomy , *ENERGY dispersive X-ray spectroscopy , *COMPOSITION of seeds , *FRUIT , *FRUIT seeds - Abstract
Objectives: Memecylon is the genus of the family Melastomataceae and their identification is somewhat difficult as a result of similarities in their intraspecies morphologies. Thus, identification of these species is much strenuous. The present study investigated the seed morphology, pharmacognostic, phytochemical, and antioxidant potential of Memecylon fruits. Materials and Methods: The species Memecylon grande, Memecylon randerianum and Memecylon umbellatum were selected for this study. The surface morphology of seeds or fruits, pharmacognostic evaluation, and phytochemical analysis are effective methods for rectifying taxonomic difficulties in authentication process and it opens a platform for pharmaceutical analysis. The surface morphology was analyzed by scanning electron microscopy (SEM) and elemental compositions were revealed by using energy dispersive X-ray spectroscopy (EDX) and inductively coupled plasma-mass spectroscopy (ICP-MS). While evaluating the pharmacognostic property of the seeds, powder microscopic analysis was used, which focusesd on the functional purity of the fruit samples. 2,2-diphenyl-1-picrylhydrazyl, hydroxyl, nitric oxide and superoxide radical scavenging assays are carried out to determine the antioxidant potential of Memecylon fruits. Results: The surface morphology of seeds had a distinct pattern of topography. SEM and EDX studies gave an insight on the elemental composition of the seeds. ICP-MS analysis showed the presence of biologically potent trace elements in the fruit samples. Quantitative estimation of secondary metabolites, such as alkaloids, terpenoids, flavonoids, and phenols, revealed that fruit extracts possess a significant amount of these phytoconstituents. The present study also reveals the antioxidant potential of Memecylon fruit extracts. Conclusion: Powder microscopy, SEM, EDX and ICP-MS analyses provided knowledge about the functional purity and elemental composition of Memecylon fruits samples. The free radical scavenging assays showed that Memecylon fruits were natural antioxidant sources. Therefore, these findings can be effectively targeted toward the pharmacological utilization of Memecylon fruits. [ABSTRACT FROM AUTHOR]
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- 2021
- Full Text
- View/download PDF
46. Dynamics of Oxidants, Antioxidants and Hormones During Different Phases of Pregnancy in Hairy Goats.
- Author
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ÇETİN, Nebi, EŞKİ, Funda, MİS, Leyla, NASEER, Zahid, and BOLACALI, Memiş
- Subjects
- *
ESTRUS , *GOATS , *GOAT breeds , *OXIDIZING agents , *PREGNANCY , *ANTIOXIDANTS , *PROGESTERONE receptors - Abstract
The aim of the present study was to observe the variation in oxidant (MDA), antioxidants (SOD, GSH, GSH-Px) and hormones (P4 and E2) levels in pregnant hairy goats during breeding season. In the this study, twenty hairy goats were synchronized by using sponges containing progesterone (fluorogestone acetate). The animals showing oestrus were inseminated twice, first at 18th -24th h and second at 36th - 48th h of oestrus. On 35th and 42nd days after insemination, pregnancy diagnosis examination was performed with transrectal ultrasonography. The blood samples were collected from pregnant goats at 0, 11, 24, 57, 100, 134, 141 days of gestation and immediately after the parturation. Serum samples collected at estrus and different stages of gestation were analyzed for MDA, SOD, GSH-Px, GSH, P4 and E2 concentrations using standard protocols. The results showed that MDA level did not change in pregnant goats. The SOD, GSH and GSH-Px levels also shown a similar pattern throughout pregnancy period. The peak (P<0.05) level of progesterone was recorded between 11th to 134th days of gestation. At time of estrus (day 0) and late gestation (day 134 and 141), the concentrations estradiol reached at maximal level (P<0.05) in hairy goats. In conclusion, the oxidants and antoixidants do not change with respect to dynamics of progesterone or estradiol level during gestation period in black hairy goats. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
47. Bazı besinlerin antioksidan özellikleri.
- Author
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Bülbül, Selda Fatma, Bulat, Gözde, Gülbahçe, Aliye, and Deprem, Gonca
- Abstract
Antioxidants are defense elements that protect the cell from damage by removing or neutralizing harmful molecules called free radicals. Balanced functioning of the antioxidant system is important for maintaining the vital functions of cells, and its degradation leads to the emergence of many diseases (such as cancer, diabetes, hypertension, respiratory diseases). Cells can produce their own antioxidants, and more over antioxidant activity is supported by the compounds such as flavonoids, polyphenols, flavones, anthocyanins, lycopenes, resveratrol, catesin, carotenoids takes place in the content of many nutrients consumed in daily life. In recent years, the rising popularity of healthy eating has brought attention to exogenous antioxidant intake. In this article, we aimed to define the antioxidant properties of foods we daily consume such as propolis, chocolate, pomegranate, grapes, turmeric and mulberry fruits. [ABSTRACT FROM AUTHOR]
- Published
- 2021
48. The Role of Oxidant and Antioxidant Parameters in the Infectious Diseases: A Systematic Literature Review.
- Author
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ÇENESİZ, Sena
- Subjects
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REACTIVE oxygen species , *COMMUNICABLE diseases , *OXIDIZING agents , *MOLECULAR structure - Abstract
The formation of reactive oxygen species is a physiological event in aerobic life. In case of infection, if the increased oxidant substances cannot be cleaned sufficiently by antioxidants, oxidative stress occurs. As a result, a number of pathological problems occur by damaging DNA, protein, carbohydrate and lipids. In biological systems, the balance between oxidants and antioxidants is important. In oxidative stress situations where the balance cannot be achieved sufficiently, support can be provided with the use of exogenous antioxidants. However, the molecular structure, route of administration and concentrations of these exogenous antioxidants are important. Otherwise, they may show a pro-oxidative effect. The present rewiev study makes a general overview of oxidative-nitrosative stress markers commonly used in infective clinical studies, antioxidant enzymes and parameters and antioxidant supplements. [ABSTRACT FROM AUTHOR]
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- 2020
- Full Text
- View/download PDF
49. Osteoartritte Beslenmenin Rolü.
- Author
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ÖZALP, Beda Büşra and SEREMET KÜRKLÜ, Nilgün
- Abstract
Copyright of Turkiye Klinikleri Journal of Health Sciences / Türkiye Klinikleri Sağlık Bilimleri Dergisi is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
50. Oksidatif Stres ve Yaşlanma.
- Author
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Tanakol, Ali, Uzunçakmak, Tuğba Kevser, and Kutlubay, Zekayi
- Abstract
Copyright of Dermatoz is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
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