Search

Sea surface temperature (SST) can be measured from space using infrared sensors on Earth-observing satellites. However, the tradeoff between spatial resolution and swath size (and hence revisit time) means that SST products derived from remote sensing measurements commonly only have a moderate resolution (>1 km). In this article, we adapt the design of a super-resolution neural network architecture [specifically very deep super-resolution (VDSR)] to enhance the resolution of both top-of-atmosphere thermal images of sea regions and bottom-of-atmosphere SST images by a factor of 5. When tested on an unseen dataset, the trained neural network yields thermal images that have an RMSE 2-3x smaller than interpolation, with a 6-9 dB improvement in PSNR. A major contribution of the proposed neural network architecture is that it fuses optical and thermal images to propagate the high-resolution information present in the optical image to the restored thermal image. To illustrate the potential benefits of using super-resolution (SR) in the context of oceanography, we present super-resolved SST images of a gyre and an ocean front, revealing details and features otherwise poorly resolved by moderate resolution satellite images.

The genus Pinna includes two species in the Mediterranean Sea: Pinna nobilis and Pinna rudis. Both these species are under threat from multiple stressors. Pinna nobilis, in particular, has been exhibiting mass mortality events (MMEs) since 2016. The population and distribution of these species have never been comprehensively explored in the Maltese archipelago, and in this work, we collate information collected between 2006 and 2019 through a number of SCUBA underwater visual census monitoring programs. The logistical barriers surrounding SCUBA-based sampling techniques and the low-density distribution of these species constitute significant obstacles to an extensive conventional population assessment. Citizen science was thus also deployed in this study to supplement the data collected through SCUBA surveys: recreational SCUBA divers worked as citizen scientists, providing data on the distribution of these two endangered species from areas never explored before. This information can be used for assessing the conservation status of P. nobilis and P. rudis in Maltese waters, whilst contributing to the next generation of ocean-literate citizens.

Introduction: Malta is a small island in the middle of the Mediterranean with a population of 514,564 inhabitants and is served by one public tertiary hospital, Mater Dei Hospital. The Vascular unit was set up in 2007. The aim of this review is to analyse the work related to peripheral arterial occlusive disease (PAOD) in Malta with an in-depth focus on amputations and revascularisation procedures since the introduction of the Vascular unit. Method: Various sources of data have been interrogated to address this subject. Population and prevalence data on obesity and type II diabetes mellitus from 2003 to 2019 was obtained from the National Statistics Office, the World Health Organization, and the International Diabetes Federation, respectively. The Maltese Vascular Register (MaltaVasc), and in-hospital reports from 2003 to 2019 was used to obtain data on revascularisation procedures, major amputations and minor amputation rates in Malta. Results: Malta has one of the highest rates of obesity in Europe. In 2015, the prevalence rate was 30.6%. Similarly, data from the International Diabetes Federation Atlas showed that the prevalence rate of T2DM among adults was 14% in 2017. There was a mean of 33 open/hybrid procedures per 100,000 population (28–38, 95% confidence interval) between 2005 and 2009 and a mean of 57 endovascular procedures per 100,000 population (46–68, 95% confidence interval) during the same time-period. From 2009 to 2019, there was a mean of 16 major amputations and 78 minor amputations per 100,000 population. Conclusion: A significant reduction in major amputation rates with an increase in minor amputation rates and revascularisation rates has been noted since the establishment of the vascular unit in Malta. During this period, there has been an increase in prevalence in obesity and T2DM together with an aging population., peer-reviewed

The CALYPSO HF radar network is a permanent and fully operational observing system currently composed of four CODAR SeaSonde stations. The system is providing real-time hourly maps of sea surface currents and waves data in the Malta-Sicily Channel. The present work aims to compare significant wave height measurements by HF Radar to wave data from numerical models and satellite altimeter. This is the first time that this set of wave data are analysed since the four HF radars were installed between 2012 and 2015. Results suggest that CODAR HF Radar wave data are a reliable source of wave information even in the case of extreme events, providing an avenue to improve and complete the offer of services deriving from the CALYPSO system. Comparisons of HF radar data with both numerical sea wave model and satellite altimeter data confirm agreement, in particular for radar measurements in the annular sectors within the central range-cells which are also characterized by a more reliable and homogeneous temporal behaviour.

Gatt, M.P., Deidun, A., Galea, A., and Gauci, A., 2018. Is citizen science a valid tool to monitor the occurrence of jellyfish? The spot the jellyfish case in the Maltese Islands. In: Shim, J.-S.; Chun, I., and Lim, H.S. (eds.), Proceedings from the International Coastal Symposium (ICS) 2018 (Busan, Republic of Korea). Journal of Coastal Research, Special Issue No. 85, pp. 316–320. Coconut Creek (Florida), ISSN 0749-0208.The potential of citizen science in monitoring transient biological phenomena occurring over large spatial scales, such as the blooming of jellyfish species, has received increased acknowledgment in recent years. The Spot the Jellyfish citizen science campaign was launched by the International Ocean Institute and by the University of Malta in the summer of 2010, with thousands of jellyfish spotting reports having been submitted by sea-users through the campaign website, social media site, smart phone app or even through email, since then. The 2011–2015 submitted jellyfish reports were analysed, besides a number of water quality parameters (temperature, salinity, chlorophyll a content, nutrient and phytoplankton concentration), whose values were gleaned for the marine area of interest through online satellite water quality data portals. The main aim of this exercise was to seek to identify possible relationships, through a variety of univariate and multivariate statistical techniques, between the distribution of submitted campaign jellyfish records and the same water quality parameters. Possible bias introduced in the report database through artefacts such as differences in bay frequentation were addressed through normalisation procedures. Spatial differences in the abundance of jellyfish reports submitted along different parts of the Maltese coastline emerged, with the highest number of such reports having been submitted along the north-eastern coastline of the island of Malta, and jellyfish sighting reports correlated well with the values of the selected water quality values. Despite this, our results indicate that besides the selected water quality parameters, other forces, possibly hydrodynamic ones, were contributing to the recorded spatial variability in jellyfish occurrence.

BACKGROUND Autologous blood-derived products can target specific inflammatory molecular pathways and have potentially beneficial therapeutic effects on inflammatory pathologies. The purpose of this study was to assess in vitro the anti-inflammatory and anti-catabolic potential of an autologous blood product as a possible treatment for COVID-19-induced cytokine storm. MATERIAL AND METHODS Blood samples from healthy donors and donors who had recovered from COVID-19 were incubated using different techniques and analyzed for the presence of anti-inflammatory, anti-catabolic, regenerative, pro-inflammatory, and procatabolic molecules. RESULTS The highest concentrations of therapeutic molecules for targeting inflammatory pathways were found in the blood that had been incubated for 24 h at 37°C, whereas a significant increase was observed after 6 h of incubation in blood from COVID-19-recovered donors. Beneficially, the 6-h incubation process did not downregulate anti-COVID-19 immunoglobulin G concentrations. Unfortunately, increases in matrix metalloproteinase 9, tumor necrosis factor alpha, and interleukin-1 were detected in the product after incubation; however, these increases could be blocked by adding citric acid, with no effect on the concentration of the target therapeutic molecules. Our data allow for safer and more effective future treatments. CONCLUSIONS An autologous blood-derived product containing anti-inflammatory and anti-catabolic molecules, which we term Cytorich, has a promising therapeutic role in the treatment of a virus-induced cytokine storm, including that associated with COVID-19.

The CALYPSO HF radar network is a permanent and fully operational observing system currently composed of four CODAR HF stations. The system is providing realtime hourly maps of sea surface currents and wave data in the Malta-Sicily Channel since 2012. Significant wave height derived from the HF radar wave measurements are confirmed to be a reliable source of wave information even in case of extreme events. However, it is noticed that the HF radar wave data are subject to differing interfering noise in the signal from unknown sources that may be competing with transmissions in the same frequency band. These interferences lead to frequent gaps and/or outliers that affect the continuity and reliability of the data set. The aim of this work is to estimate missing values and to detect possible outliers building and fitting a Markov chain mixture model on the significant wave height data collected at the four stations. It is verified that the proposed procedure is sufficiently robust since the model estimates succeed to classify radar observations with a high percentage of missing data and to equally highlight spikes and outliers., peer-reviewed

The referral of patients for open heart surgery, presenting with a history of heparin hypersensitivity instigated a multidisciplinary effort to find an alternative anticoagulant to heparin. The various options mentioned in the literature call for changes in the routine practice of open heart surgery on cardiopulmonary bypass. These changes involve mostly the perfusion setup and conduct on bypass and to a lesser extent the anesthetic and surgical practice. Nevertheless, the different professions involved in the cardiac surgical firm discussed the proposed changes in a multidisciplinary effort. A new protocol was drafted, endorsed, and executed. The authors highlight these changes and their successful use in the subsequent case study.

In the present paper, we use numerical simulation to investigate currents, mixing and water renewal in Barcelona harbour under typical conditions of wind forcing for the winter season. This site is of particular importance due to the interplay between touristic and commercial activities, requiring detailed and high-definition studies of water quality within the harbour. We use Large Eddy Simulation (LES) which directly resolves the anisotropic and energetic large scales of motion and parametrizes the small, dissipative, ones. Small-scale turbulence is modelled by the anisotropic Smagorinsky model (ASM) to be employed in presence of large cell anisotropy. The complexity of the harbour is modelled using a combination of curvilinear, structured, non-staggered grid and the immersed boundary method. Boundary conditions for wind and currents at the inlets of the port are obtained from in-situ measurements. Analysis of the numerical results is carried out based on both instantaneous and time-averaged velocity fields. First- and second-order statistics, such as turbulent kinetic energy and horizontal and vertical eddy viscosities, are calculated and their spatial distribution is discussed. The study shows the presence of intense current in the narrow and elongated part of the harbour together with sub-surface along-shore elongated rolling structures (with a time scale of a few hours), and they contribute to the vertical water mixing. Time-averaged velocity field reveals intense upwelling and downwelling zones along the walls of the harbour. The analysis of second-order statistics shows strong inhomogeneity of turbulent kinetic energy and horizontal and vertical eddy viscosities in the horizontal plane, with larger values in the regions characterized by stronger currents. The water renewal within the port is quantified for particular sub-domain regions, showing that the complexity of the harbour is such that certain in-harbour basins have a water renewal of over five days, including the yacht marina area. The LES solution compares favourably with available current-meter data. The LES solution is also compared with a RANS solution obtained in literature for the same site under the same forcing conditions, the comparison demonstrating a large sensitivity of properties to model resolution and frictional parametrization.

Objective To describe the epidemiology of the serosubtypes of Neisseria meningitidis serogroup B (MenB) in the most densely populated area in Europe and to review the MenB Porin A (PorA) based outer membrane vesicle (OMV) vaccines that could provide the broadest protection. Study design and setting Active surveillance of invasive meningococcal disease in a population of 400,000 inhabitants in Malta from 1999 to 2006. Serogroup B isolates were serosubtyped and analysed by age and year. The suitability of OMV vaccines was then assessed. Results Laboratory confirmation of invasive meningococcal disease was obtained in 48% (79/163) of notified cases. Serogroup B caused the majority of invasive meningococcal disease (76%, 60/79) with the greatest disease burden occurring in 0–14-year-old children (73%, 44/60). MenC caused 14% (11/79) of cases. The most prevalent MenB serotype:serosubtype combination was B:4:P1.19,15 which constituted 59% (34/58) of all phenotypeable MenB isolates. The PorA epitopes P1.15 and P1.19, detected in 74% (43/58) of isolates, were significantly more prevalent than serosubtypes with other PorA epitopes ( χ 2 : 7.18, P Conclusion An assessment of the usefulness of a MenB OMV vaccine in Malta requires further research. The wild-type OMV vaccine developed by the Finlay Institute (FI) in Cuba could potentially be used to control an outbreak with a MenB P1.19,15 clone. A multivalent OMV vaccine would however be needed for broader protection against the endemic heterogenous MenB strains. A serogroup B vaccine incorporating more conserved proteins than PorA would be more suitable for comprehensive control of meningococcal B disease.

A 74-year-old man on warfarin for aortic valve replacement presented with recurrent episodes of melaena. An initial oesophagogastroduodenoscopy (OGD) was normal, as were red cell scanning and colonoscopy. It was a third OGD that revealed the cause of the melaena—a vascular lesion in the duodenum, at the junction between D1 and D2. An extragastric Dieulafoy's lesion was diagnosed, and the lesion was injected with epinephrine and tattooed. Over the following months, episodes of bleeding recurred despite further attempts at injection. Percutaneous radiologically assisted embolisation of the gastroduodenal artery, and eventually duodenotomy and oversuturing of the lesion were performed to no avail. The patient has undergone over 10 endoscopies, and has received over 70 units of packed red cells to date, since his initial presentation 6 years ago. Attempts to stop the bleeding permanently have been difficult, highlighting the complexity of managing such a lesion.