1. Alcohol consumption and oesophageal squamous cell cancer risk in east Africa: findings from the large multicentre ESCCAPE case-control study in Kenya, Tanzania, and Malawi
- Author
-
Daniel R S Middleton, Blandina T Mmbaga, Diana Menya, Charles Dzamalala, Gissela Nyakunga-Maro, Peter Finch, Yohannie Mlombe, Joachim Schüz, Valerie McCormack, Nicolas Kigen, Margaret Oduor, Stephen Karuru Maina, Fatima Some, Caroline Kibosia, Amos Mwasamwaja, Alex Mremi, Ireen Kiwelu, Remigi Swai, Godwin Kiwelu, Sophia Mustapha, Eliawawomy Mghase, Amana Mchome, Redfan Shao, Evarista Mallya, Kajiru Kilonzo, Anstead Kamkwantira, Mercy Kamdolozi, George Liomba, Steady Chasimpha, Clement Narh, Liacine Bouaoun, Behnoush Abedi-Ardekani, Godfrey Mushi, Theresia Namwai, Mary Suwedi, Thandiwe Solomon, Rose Malamba, and Christine Carreira
- Subjects
Alcohol Drinking ,Esophageal Neoplasms ,Risk Factors ,parasitic diseases ,Humans ,Articles ,Esophageal Squamous Cell Carcinoma ,General Medicine ,Africa South of the Sahara - Abstract
Summary Background The contribution of alcohol to the large burden of oesophageal squamous cell carcinoma (ESCC) in east Africa remains uncertain and difficult to assess owing to complex consumption patterns of traditional and commercial drinks. We aimed to assess whether alcohol drinking, overall and at specific intake levels, contributes to ESCC risk in east Africa. Methods We did a hospital-based case-control study in Kenya, Tanzania, and Malawi, which included comprehensive assessment of a variety of locally consumed alcohol that we used to classify drinkers as exclusively low alcohol-by-volume (ABV
- Published
- 2022
- Full Text
- View/download PDF