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Background: The IMF fears the COVID-19 pandemic will create an economic down-turn matching the Great Depression. More recent recessions\ud have led to physical and mental health problems including suicide deaths of\ud young adults (15 - 34). We aim to identify risk patterns of mortality by age\ud from influenza and suicide mortality in peak years from 1979 to 2016 to see if\ud there are lessons to be learned for policy makers and psychiatric services.\ud Method: Using WHO mortality data for 1979-2016 peak years of influenza\ud deaths and suicides are identified in ten Western countries. Death rates per\ud million in each age-band are calculated for both sexes and the percentage of\ud the total deaths accruing in each of five age-bands for influenza and suicides.\ud Ratios of influenza to suicide by age in regard to rates and percentages of\ud deaths indicate differential risk mortality and morbidity patterns. Results: Of\ud the ten country’s average Influenza deaths, 95% occurred in people over 55,\ud including 80% - 85% for the over 75’s. Conversely it was 59% of suicides occurred in peoples aged

Aims: To examine whether increased neurological deaths during 21st Century are predominately due to elderly demographics, or major influences of interactive-multiple environmental contributory factors? We examine WHO Early-Adult-Deaths (55-74yearolds), which is below Western life-expectancy, and total Age-Standardised-Death-Rates (ASDR) controlled by age, sex, and population, to challenge the demographic assumption. Method. Based upon WHO latest global neurological mortality categories, Nervous-Disease-Deaths and Alzheimer’s & Other Dementias, which provides the Combined Neurological Death, rates per million (pm), for the twenty-one West-Developed-Nations (WDN) over the period. Early-Adult-Death rates based upon numbers of deaths, divided by 55-74 population and WHO total ASDR during the 21st Century. Increases between Over 75’s population and Over 75’s neurological mortality is compared using Odds Ratios. Numbers of deaths are indicative of family and services pressures. Results: Every country’s 55-74yearolds Nervous-Disease-Deaths rates were higher than Alzheimer’s & Dementia Deaths, ten countries Nervous-Disease-Deaths rose higher than Alzheimer’s & Dementias during Century. Highest Combined Deaths and increases were Finland 1006 per million (pm) up 44%, USA 710pm, rose 39% and UK 653pm a rise of 32%, countries average of 25%, though Belgium, Canada and France rates fell. Highest ASDR were Finland 973pm, up 104%, USA 592pm, rose 76%, UK 553pm, increase 170%. Lowest were Japan 112pm, yet up 90%, Greece 184pm, rose 64% and Austria 214pm increased 102%, average nation’s 62%. Belgium at 387pm up 34%, Canada 401pm, increased 13% and France ASDR 336pm up 11%. Population compared with total neurological amongst Early-Adult-Deaths and Over 75’s, ratios of change, were respectively 1:1.34 and 1:2.21, yielding an Odds ratios of 1:1.65 French total neurological numbers were 40,594 rose to 71,543, up 76%, UK 24,601 to 103,550 increased 321% and the USA 174,708 to 436,438 rising 150%. Discussion: We reject the hypothesis that neurological increases were mainly dues to demographics. Our results support by new studies across the continents, with their findings of significant causal multiple-interactive-environmental pollutants, including, endocrine disruptive chemicals, air pollution, organophosphates, plastics, petrochemicals, impact of low ubiquitous prolonged electro-magnetism, etc, associated with neuro-degenerative disease, especially Early-Onset-Dementia, below Western life-expectancy. Conclusions: Governments should seek urgent research to explain this new epidemic.

Objectives A population-based controlled study to determine whether adult (55-74 years) neurological disease deaths are continuing to rise and are there significant differences between America and the twenty developed countries 1989-91 and 2012-14. Method Total Neurological Deaths (TND) rates contrasted against control Cancer and Circulatory Disease Deaths (CDD) extrapolated from WHO data. Confidence intervals compare USA and the other countries over the period. The Over-75's TND and population increases are examined as a context for the 55-74 outcomes. Results Male neurological deaths rose >10% in eleven countries, the other countries average rose 20% the USA 43% over the period. Female neurological deaths rose >10% in ten counties, averaging 14%, the USA up 68%. USA male and female neurological deaths increased significantly more than twelve and seventeen countries, respectively. USA over-75s population increased by 49%, other countries 56%. Other countries TND up 187% the USA rose fourfold. Male and female cancer and CDD fell in every country averaging 26% and 21%, respectively, and 64% and 67% for CDD. Male neurological rates rose significantly more than Cancer and CCD in every country; Female neurological deaths rose significantly more than cancer in 17 countries and every country for CDD. There was no significant correlation between increases in neurological deaths and decreases in control mortalities. Conclusions There are substantial increases in neurological deaths in most countries, significantly so in America. Rises in the 55-74 and over-75's rates are not primarily due to demographic changes and are a matter of concern warranting further investigation.

© 2019 Elsevier Ltd Whilst humans evolved in the earth's Electro-Magnetic-Field (EMF) and sun-light, both being essential to life but too much sun and we burn. What happens if background EMF rise to critical levels, coinciding with increasing environmental pollutants? Two of the authors can look back over 50 clinical years and appreciate the profound changes in human morbidity across a range of disparate conditions – autoimmune diseases, asthma, earlier cancer incidence and reduced male sperm counts. In particular have been increased autism, dyslexia, Attention Deficit Hyperactivity Disorder and neurological diseases, such as Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Parkinson's Disease, Early Onset Dementia, Multiple System Atrophy and Progressive Supranuclear Palsy. What might have caused these changes-whilst genetic factors are taken as given, multiple environmental pollutants are associated with neurological disease although the mechanisms are unclear. The pace of increased neurological deaths far exceeds any Gompertzian explanation - that because people are living longer they are more likely to develop more age-related problems such as neurological disease. Using WHO global mortality categories of Neurological Disease Deaths (NDD) and Alzheimer's and Dementia deaths (Alz), updated June 2018, together they constitute Total Neurological Mortality (TNM), to calculate mortality rates per million for people aged 55–74 and for the over-75's in twenty-one Western countries. Recent increases in American people aged over-75's rose 49% from 1989 to 2015 but US neurological deaths increased five-fold. In 1989 based on Age-Standardised-Deaths-Rates America USA was 17th at 324 pm but rising to 539 pm became second highest. Different environmental/occupational factors have been found to be associated with neuro-degenerative diseases, including background EMF. We briefly explore how levels of EMF interact upon the human body, which can be described as a natural antennae and provide new evidence that builds upon earlier research to propose the following hypothesis. Based upon recent and new evidence we hypothesise that a major contribution for the relative sudden upsurge in neurological morbidity in the Western world (1989–2015), is because of increased background EMF that has become the tipping point-impacting upon any genetic predisposition, increasing multiple-interactive pollutants, such as rises in petro-chemicals, hormone disrupting chemicals, industrial, agricultural and domestic chemicals. The unprecedented neurological death rates, all within just twenty-five years, demand a re-examination of long-term EMF safety related to the increasing background EMF on human health. We do not wish to 'stop the modern world’, only make it safer.

The interplay between the human brain and the environment is both dynamic and mysterious. For millennia phenomena have been experienced and observed by our ancestors of all cultures. But in the present Anthropocene age for human beings, many scientists still dismiss phenomena as “anecdotal” and not worthy of study. Beware the reductive power of science and research – good science advances on the wings of hypotheses. Genetics has loaded the gun but our environment pulls the trigger. There are no unnatural or supernatural phenomena – there are only very large gaps in our knowledge of what is natural. Thus the many bountiful phenomena which are covered in five domains of this paper have natural explanations – in physics and geophysics – in the slow brainwaves of human beings capable of entrainment – the waves of Natural systems – in action at a distance – in the piezo-electric signals generated by the crystals surrounding the pineal gland and our dna – itself a Fractal antenna. As the Roman Senator Seneca wrote “The language of truth is simple.”

Objective: To test whether the Village incidence of new cases of Motor Neurone Disease (MND) over an 8-year period, is significantly different from those in the County to serve as a pilot study to identify possible interactive multienvironmental aetiology. Design: Between September 2003-June 2011, Village MND cases were compared with the County’s in people aged >54 years. The incidence of MND was determined and Odds ratios calculated. The Village MND mortality rates were juxtaposed against England & Wales MND deaths over the period. Setting: A rural Village flanked by Electro-Magnetic-Fields (EMF) close to an active airfield. The Village population has remained relatively stable, plane-take off from the airfield is at a low angle for 3-4 miles, with radar TACAN beams pulsed every 4 seconds. Participants: General population (>54 yrs) in Village and County. Main outcome measures: Cases and deaths of MND. Results: Of the County’s 236 MND cases, 11came from the Village, equal to 1 MND case per 410 people, County rate was 1: 1,844, yielding an Odds ratio of 4.5:1. Village MND deaths compared to England & Wales gave an Odds ratio of 2.3: 1; England & Wales MND deaths were double the County’s. Conclusion: The disproportionate incidence of Village MND, with its relatively intensive exposure to EMF and petrochemicals, leads us to a speculative hypothesis of possible multi-interactive environmental influences. Despite limitations inherent in cluster studies, these indicative results suggest that a more detailed national study of geographic, occupational, life-style and family background is merited and feasible.