1. Twenty‐Four‐Month Blood Pressure Results After Renal Denervation Using Endovascular Ultrasound
- Author
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Sebastian Rosch, Karl‐Philipp Rommel, Stephan Blazek, Karl‐Patrik Kresoja, Anne Schöber, Maximilian von Roeder, Steffen Desch, Holger Thiele, Philipp Lurz, and Karl Fengler
- Subjects
arterial hypertension ,renal denervation ,resistant hypertension ,ultrasound renal denervation ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BACKGROUND Renal denervation has proven its efficacy to lower blood pressure in comparison to sham treatment in recent randomized clinical trials. Although there is a large body of evidence for the durability and safety of radiofrequency‐based renal denervation, there are a paucity of data for endovascular ultrasound–based renal denervation (uRDN). We aimed to assess the long‐term efficacy and safety of uRDN in a single‐center cohort of patients. METHODS AND RESULTS Data from 2 previous studies on uRDN were pooled. Ambulatory 24‐hour blood pressure measurements were taken before as well as 3, 6, 12, and 24 months after treatment with uRDN. A total of 130 patients (mean age 63±9 years, 24% women) underwent uRDN. After 3, 6, 12, and 24 months, systolic mean 24‐hour ambulatory blood pressure values were reduced by 10±12, 10±14, 8±15, and 10±15 mm Hg, respectively, when compared with baseline (P
- Published
- 2023
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