3 results on '"Anne Kinmonth"'
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2. Vox Sanguinis International Forum on paediatric indications for blood component transfusion:Summary
- Author
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Julián Sevilla, Wendy Lau, Gemma Crighton, Helen Savoia, Araci M. Sakashita, Ana P. H. Yokoyama, Hana Lejdarová, Pavel Trakhtman, Meghan Delaney, Marian van Kraaij, Elise J. Huisman, Helen V New, Hitoshi Okazaki, Hartirathpal Kaur, Praveen Kumar, Giuseppina Facco, Miquel Lozano, Joyce Lam Ching Mei, Mie Topholm Bruun, Ratti Ram Sharma, Yutaka Nagura, Anne Kinmonth, Josune Zubicaray, Kjell Titlestad, Rekha Hans, E. Zhiburt, Koh Pei Lin, Lakhvinder Singh, Costantino Avdis, Joanne Yacobovich, Paola Manzini, Agneta Wikman, Selina Ho Kah Ying, Mary Comande, Nikolay Starostin, Philip C. Spinella, Emöke Deschmann, Dana E. Pavlova, Rachel Moss, Jose Mauro Kutner, Vered Yahalom, Mitsuteru Hiwatari, and Mark H. Yazer
- Subjects
medicine.medical_specialty ,business.industry ,Blood Component Transfusion ,MEDLINE ,Medicine ,Hematology ,General Medicine ,business ,Intensive care medicine - Published
- 2019
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3. The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia
- Author
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Donald M. Arnold, Francois Lauzier, Martin Albert, David Williamson, Na Li, Ryan Zarychanski, Chip Doig, Lauralyn McIntyre, Andreas Freitag, Mark Crowther, Lois Saunders, France Clarke, Rinaldo Bellomo, Ismael Qushmaq, Renato D. Lopes, Diane Heels‐Ansdell, Kathryn Webert, Deborah Cook, Rick Hall, Graeme Rocker, Lisa Julien, Debbie Wright, Caroline Roy, Judy Theriault, Susan Pleasance, Maureen Meade, Lori Hand, Christine Wynne, Mark Duffett, Michelle Kho, Nicole Zytaruk, John Granton, Andrea Matte, Paulina Farias, Leslie Chu, Nancy Brockest, Stephanie Go, Margaret McGrath‐Chong, Madison Dennis, Marc Lipkus, Emily Stern, Ryan Albert, Stephan Langevin, Alexis F Turgeon, Marie‐Claude Tremblay, Martine Blais, Maxime Beauparlant, Julie Asselin, Chantal Gagne, Marie Thibodeau, Germain Poirier, Sandrine Spearson, Isabelle Neas, Joe Pagliarello, Paul Hébert, Irene Watpool, Tracy McArdle, Claude Gaudert, Paule Marchand, Carson Davidson, Mary‐Jo Lewis, Erin Murphy, Julia Foxall, Yoanna Skrobik, Johanne Harvey, Stefania Chitu, Virginie Williams, Carole Sirois, Carole Nadon, Stephanie Dolle, Audrey‐Anne Gosselin, Patrice Deroy, Geeta Mehta, Sumesh Shah, Cheryl Ethier, Sam Tirgari, Lindsay Steinberg, Rod McDonald, Vidhya Sivanantham, Kristofer Bandayrel, Friederike Quittnat Pelletier, Marnie Kramer‐Kile, Maedean Brown, Scott Kim, Rob Fowler, Nicole Marinoff, Karen Code, Boris Bojilov, Derek Parsotam, John Marshall, Orla Smith, Beth Fry, Kerri Porretta, Yoon Lee, Jeanna Morrissey, Victoria Wen, John Muscedere, Miranda Hunt, Susan Fleury, Nicole Godfrey, Sharlene Hammond, Elizabeth Mann, Monica Myers, Amber Robinson, Donald Griesdale, Dean Chittock, Vinay Dhingra, Denise Foster, Maureen Gardner, Susan Logie, Roger Autio, Dara Davies, Pia Ganz, Laurie Smith, Peter Dodek, Victoria Alcuaz, Betty Jean Ashley, Sheilagh Mans, Niall Ferguson, James Stevenson, Joel Elman, Timothy Karachi, Tina Millen, Andrea Tkaczyk, Mike Jacka, Marleen Irwin, Carmen Chan, Leeca Sonnema, Kelly Marsh, Jennifer Maurer, Tamara Kreidl, Candice Varden, Carey Kinjerski, Christopher Doig, Stacy Ruddell, Linda Knox, Crystal Wilson, Kevin Champagne, Gordon Wood, Fiona Auld, Leslie Atkins, Bojan Paunovic, Nicole Marten, Kym Wiebe, Ellen McDonald, Sean Keenan, Steven Reynolds, Miroslav Svetik, Mary Van Osch, Jim Kutsogiannis, Patrica Thompson, Norine Whalen, Francois Lellouche, Marie‐Claude Ferland, Patrick Dussault, Caroline Jacob, Marie‐Eve Morneau, Nancy Laberge, Kosar Khwaja, Laura Banici, Lena Havell, Olivier Lesur, Francois Lamontagne, Sandra Proulx, Gerald Hollinger, Vasanti Shende, Vanessa Belcastro, Bill Plaxton, Anders Foss, Jonathan Eisenstat, Tammy Doerle, Michael Sharpe, Mona Madady, Jamie Cooper, Andrew Davies, Shirley Vallance, Cindy Weatherburn, Jasmin Board, Victoria Bennett, Simon Finfer, Naresh Ramakrishnan, Simon Bird, Julie Potter, Anne O’Connor, Susan Ankers, Jack Cade, Deborah Barge, Tania Caf, Belinda Howe, Glenn Eastwood, Leah Peck, Donna Goldsmith, Kim O’Sullivan, David Ernest, Sam Radford, Ann Whitfield, Anthony Cross, Suzanne Eliott, Jaspreet Sidhu, Inga Mercer, Angela Hamilton, John Botha, Jodi Vuat, Sharon Allsop, Nina Fowler, Tim Crozier, Jonathan Barrett, Chris Wright, Pauline Galt, Carly Culhane, Rebecca Ioannidis, Sue Burton, Marnie Reily, Cyveen Weeraratna, Ian Seppelt, Leonie Weisbrodt, Robyn Bond, Nepean Hospital, Justine Rivett, Stephanie O’Connor, Alex Poole, Clive Woolfe, Dorrilyn Rajbhandari, Caitlin Rees, John Edington, Jason Fletcher, Julie Smith, Catherine Boschert, Graham Reece, Treena Sara, Kiran Nand, Andrew Bersten, Alex Gallus, Elisha Matheson, Margie O’Callaghan, Neil Orford, Tania Elderkin, Melissa Fraser, Allison Bone, Tania Salerno, Anne Kinmonth, Subhash Arora, Bridget O’Bree, Katherine Shepherd, Alan –Quinn, Martin Sterba, Bronwyn Ruth Johnson, Renee Xu, Francisco Hill, Rajaram Ramadoss, Josette Wood, Marcelo Garcia da Rocha, Andréa Kramer, Martha Hädrich, Nilton Brandao, Cassiano Teixeira, Cíntia Roehrig, Juliana Zeni, Suzana Alves da Silva, Rubens Costa Filho, Renato Correa, Alves Moreira, Plínio N. Gomes, Rodrigo Biondi, Otavio Berwanger, Edson Romano, Anna Maria Buehler, Helio Penna Guimarães, Adriano Truffa, Rosana Nakamura, Lillian Mazza Barbosa, Jean Brennick, Sawsan Bassi, Mohammed Alsultan, Yaseen Arabi, Riette Brits, Jamal Alhashemi, Sanaa Shalabi, Yasser Mandourah, Nadeem Shaikh, Manal Al‐Hazmi, M. Ali Al‐Azem, Trevor Wyngaard, Barbara Smithson, Nicholas E Vlahakis, Laurie Meade, Michael Cox, Jackie O’Brien, Catherine Krause, Joseph Nates, Sajid Haque, Deidre Mooring, Rose Erfe, Paula Nickerson, Tony Sherry, John Smith, Barnaby Sanderson, Josephine Ng, John Brooks, Ling Lim, and Katie Lei
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medicine.medical_specialty ,Anemia ,Population ,thrombocytopenia ,030204 cardiovascular system & hematology ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,Internal medicine ,medicine ,Platelet ,education ,transfusion ,education.field_of_study ,business.industry ,Hazard ratio ,Original Articles ,Hematology ,medicine.disease ,mortality ,Intensive care unit ,Thrombosis ,3. Good health ,critical care ,Platelet transfusion ,030228 respiratory system ,Online‐only Articles ,platelets ,Original Article ,Medical emergency ,hemorrhage ,business ,Cohort study - Abstract
Background Platelet transfusions are commonly used to treat critically ill patients with thrombocytopenia. Whether platelet transfusions are associated with a reduction in the risk of major bleeding is unknown. Patients/Methods Observational cohort study nested in a previous multicenter, randomized thromboprophylaxis trial in the intensive care unit (ICU). The objective was to evaluate the association between platelet transfusions and adjudicated major bleeding events. Platelet transfusion episodes were reviewed for timing of administration, product type, and dose. Major bleeding with and without platelet transfusions was adjusted for severity of thrombocytopenia, use of anti‐platelet agents, surgery and other covariates. Secondary outcomes were thrombosis, death in ICU and platelet count increment. Results Among 2,256 patients, 71 (3.1%) received 190 platelet transfusions. Of those, 121 (63.7%) were administered to 54 non‐bleeding, thrombocytopenic patients. Adjusted rates of major bleeding were not statistically different with or without the administration of platelet transfusions (hazard ratio for transfused patients 0.85; 95% confidence interval, 0.42‐1.72). We did not find a significant association between platelet transfusion use and thrombosis or death in ICU in adjusted analyses. Thrombocytopenia, anemia, major or minor bleeding and use of anticoagulants were associated with platelet transfusion administration. The median post‐transfusion platelet count increment was 20×109/L at 3.5 hours post‐transfusion. Conclusions Rates of major bleeding were not different for patients who did and did not receive platelet transfusions. Inferences were limited by the small number of transfused patients. Clinical trials are needed to better investigate the potential hemostatic benefit and potential harms of platelet transfusions for this high‐risk population.
- Published
- 2017
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