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Byline: Gopikrishnan. Anjaneyan, Nandhetha. Sreenivaasan, Lekshmi. Sajini, C. Mithun, Asmita. Mehta Sir, A woman in her 50s presented with itchy rashes over the forehead for a duration of three months. [...]

Byline: Rita. Vora, Rahul Krishna. Kota, Rochit. Singhal, Gopikrishnan. AnjaneyanContext: Androgenic alopecia (AGA) is a hereditary androgen-dependent disorder, characterized by gradual conversion of terminal hair into miniaturized hair and defined [...]

Byline: Soumya. Jagadeesan, V. Anilkumar, Vinitha. Panicker, Gopikrishnan. Anjaneyan, Jacob. Thomas Mycobacterium chelonae is a rapidly growing non-tuberculous mycobacterium. The skin and soft tissue infections due to this organism are [...]

Byline: Pradeep. Balasubramanian, Soumya. Jagadeesan, Gopikrishnan. Anjaneyan, Jacob. Thomas Sir, Anagen effluvium is the abrupt loss of hairs that are in their growing phase (anagen) due to an event that [...]

Byline: Rita. Vora, Gopikrishnan. Anjaneyan, Rajat. Gupta Cutaneous angiosarcoma is a rare aggressive tumor of capillary and lymphatic endothelial cell origin. Cutaneous angiosarcoma of the head and neck regions seems [...]

However, I CV i sepsis with extensive violaceous to hemorrhagic and pus-filled vesiculobullous eruptions has never been reported. Fatal Chromobacterium violaceum septicaemia in northern Laos, a modified oxidase test and post-mortem forensic family G6PD analysis. I Chromobacterium violaceum (CV) i , a gram-negative bacillus, can manifest as localized skin and soft tissue infections to severe and fatal systemic infections with high case fatality rates (up to 60%), particularly in children with chronic granulomatous disease (CGD).1 We present a case of disseminated I CV i infection with widespread polymorphic skin eruptions. [Extracted from the article]

Introduction: Juvenile-onset systemic lupus erythematosus (SLE) is one of the most common systemic autoimmune connective tissue disorders in children. Studies focusing on the mucocutaneous manifestations of childhood lupus are scanty in literature. Objectives: This study was an attempt to describe the cutaneous changes seen in Pediatric Lupus and to correlate with the histopathological and immunofluoresecence findings. Methods: This was a retrospective study. All children under the age of 18 years who were diagnosed to have SLE according to the ACR criteria and presented to the dermatology outpatient department during a period of 1 year were included in the study. Details including clinical features, investigation findings including immunological tests and skin biopsy findings were noted. The analysis was performed using descriptive statistical tools such as percentage and frequency. Results: A total of 14 cases, average age at presentation was 10.14 years. Among the cutaneous manifestations, the most common presenting feature was urticarial vasculitis. Malar rash was seen in 57% of cases. Other cutaneous features seen were diffuse alopecia, oral ulcers. Antinuclear antibody was positive in all cases. Conclusion: Pediatric lupus tends to have a more aggressive course than adult lupus. Early diagnosis and treatment is necessary to prevent progression and development of complications. [ABSTRACT FROM AUTHOR]

Objective To assess the trichoscopic features of alopecia areata, and determine correlation between the findings and the severity of alopecia tool (SALT) score . Methods A cross-sectional study was done on 67 patients in Amrita Institute, Kochi, who were clinically diagnosed with alopecia areata of scalp. Patients were examined using Heine Delta 20 Plus dermoscope. Results Yellow dots were the most common finding on trichoscopy, seen in 86.6% of patients. Black dots were next most common finding, seen in 68.7% of patients, followed by broken hair (59.7%), vellus hair (49.3%) and tapering hairs (25.4%). Grey hair was seen in 11.9% and coiled hair in 7.5% patients. There was a significant relationship between vellus hair and lower SALT score. This study did not find any significant association between the other trichoscopic features of alopecia areata and clinical type or SALT score. Conclusion Scalp lesions in alopecia areata show characteristic features on trichoscopy, such as yellow dots, black dots, broken hair, vellus hair and tapering hair. Trichoscopy is a quick, easy tool in the diagnosis of alopecia and it can be a non-invasive alternative to skin biopsy. [ABSTRACT FROM AUTHOR]

Mycobacterium chelonae is a rapidly growing non-tuberculous mycobacterium. The skin and soft tissue infections due to this organism are steadily on the rise and need to be delineated specifically as most of these are not responsive to routine antituberculosis treatment. Here, we report 3 different presentations caused by Mycobacterium chelonae in traumatic and surgical wounds. Mycobacterium chelonae can complicate surgical or traumatic wounds.This infection may also present as injection site abscesses. Diabetics on insulin injections are especially at risk. A high index of suspicion is necessary in long standing culture negative lesions for clinching the diagnosis. PCR can be helpful in confirming the diagnosis. [ABSTRACT FROM AUTHOR]

Sarcoidosis is a multisystem, granulomatous disease of unknown etiology that can affect the pulmonary, reticulo-endothelial, skin, gastrointestinal, cardiac, musculo -- skeletal, endocrine or central nervous system. Exclusive cutaneous involvement is very rare in sarcoidosis. Lupus pernio is a variant of cutaneous sarcoidosis presenting with erythematous to violaceous nodules and plaques located symmetrically over the nose, cheeks, ears and digits. We present a case of lupus pernio which showed rapid improvement with topical steroids and has yet not developed any systemic involvement even after 6 years of regular follow up. [ABSTRACT FROM AUTHOR]

Most common form of cutaneous tuberculosis (TB) is lupus vulgaris, which usually occurs in previously sensitized individuals who have a high degree of tuberculin sensitivity. Various forms including plaque, ulcerative, hypertrophic, vegetative, papular, and nodular forms have been described. We are reporting a case of a young female, who presented with 6 well defined erythematous scaly plaques involving both arms and a puckered scar on right forearm and right breast. Clinically, it was looking like lupus vulgaris with cold abscess, few lesions mimicking scrofuloderma, but skin biopsy from both the types of lesions revealed lupus vulgaris. Patient improved with Anti Tuberculous Therapy and surgical drainage of underlying cold abscess. [ABSTRACT FROM AUTHOR]

Ectodermal dysplasia is a rare disorder. Christ-Siemens-Touraine syndrome (Hypohidrotic Ectodermal dysplasia (HED)) is a diffuse, non-progressive disease present at birth and involves at least two tissues of ectodermal origin. It is caused by mutation in gene ectodysplasin (EDA, EDA1)located at Xq12-13. Main clinical feature of HED is sparse or absent eccrine gland as well as hypotrichosis, nail, and teeth abnormality with characteristic faces. The absence or diminished activity of sweat gland results in patients having more chances of developing hyperthermia and with intolerance to warm environment. Most do well with simple measures such as wet clothes, air conditioning, wet bands etc. We present cases of two brothers, born of non-consanguineous marriage, who presented to us with complaints of heat intolerance and abnormal facial features [ABSTRACT FROM AUTHOR]