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Background: Infection is one of the challenging complications after open reduction and internal fixation for ankle fractures. Previously published case series conclude that Staphylococcus aureus is the most frequent causative microorganism. An unexpected increase in Enterobacter cloacae infections after this surgery was observed in a preliminary analysis of data at the promoting center of the study. In traumatology, its incidence has been reported in chronic osteomyelitis, prosthetic infections, septic osteoarthritis, open fractures in children and adults, and fractures other than the ankle. Because of this unexpected finding, we decided to perform this study to analyze the demographic and microbiological variables of acute osteosynthesis infection after ankle fracture and determine the distinctive features of the patients with E cloacae infection., Methods: We performed a retrospective multicenter study including 4 university hospitals. All patients diagnosed with acute osteosynthesis infection after ankle fracture fixation between January 2015 and December 2018 were included. We analyzed demographic data, type of fracture, surgical technique, and microorganisms responsible for the infection. We performed a descriptive statistical analysis of the variables. Univariate and multivariate regression analysis were performed to compare patients with E cloacae infection to patients with infection caused by other microorganisms., Results: A total of 65 patients were included. A predominance of polymicrobial infections (24.62%), followed by infections caused by S aureus (23.07%) and E cloacae (23.07%) was observed. When E cloacae isolated in polymicrobial infections were added, the incidence of E cloacae as a causative microorganism increased to 32.3%. Patients with E cloacae infection were older (64/53, P  = .008) and had a higher requirement of negative-pressure therapy after surgical debridement (71%/40%, P  = .017)., Conclusion: A high incidence of E cloacae infections was observed. Patients with E cloacae infection were generally older and required a higher use of negative-pressure therapy after debridement., Level of Evidence: Level V, mechanism-based reasoning.

Objective: To evaluate the influence of tourniquet pressure (TP) on the postoperative pain of patients undergoing total knee arthroplasty (TKA)., Material and Methods: This prospective double-blind study enrolled 86 patients scheduled for TKA. The patients were randomized to groups to receive either a high TP (400 mgHg) or a low TP (100 mgHg above systolic pressure). A spinal block was performed in each patient. Intravenous morphine and metamizol were infused through a patient-controlled analgesia device. Postoperative pain was estimated on a visual analog scale (VAS). We also recorded the amount of morphine infused, functional recovery of the limb and the presence of complications., Results: Surgical field conditions were considered good in all but two low PT cases. Postoperative pain was less intense in the low TP group at 6, 12, 24 and 36 hours, and that group required less morphine (11.38 +/- 4.9 mg vs. 15.13 +/- 4.9 mg, p < 0.05). More patients achieved 90 degrees flexion four days after surgery in the low TP group (65%) than in the high TP group (41%) (p < 0.05)., Conclusions: Applying a lower-than-usual TP in orthopedic surgery could be sufficient for reducing postoperative pain while still providing a bloodless surgical field.