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Excessive use and abuse of disinfectants over the past century has created problems associated with the emergence of resistant microorganisms. In addition, there is always a potential risk to human and animal health, as the use of aggressive disinfectants can lead to diseases. The purpose of the study was to investigate the toxicity of an ex perimental disinfectant to determine the possibility of its use in the presence of humans and animals. Study material – an experimental product (water-soluble disinfection powder). Experimental studies were conducted at the premises of a certified vivarium of the ECOMEDCHIM regional centre of Sumy State University and Sumy National Agrarian University. Acute toxicity of the preparation was studied on 30 white mice weighing 19.5±1.0 and 15 white rats weighing 200±15.0 g. Determination of toxicity by prolonged oral administration was studied in two analogous groups of white rats, 6 animals each with a bodyweight of 185±10.0 g. The effect of the preparation on the state of internal organs was evaluated by comparing relative mass coefficients. The local irritating effect of the preparation was determined by skin applications on 10 rabbits weighing 2.97±0.3 kg. The disinfectant, when administered orally once at doses of 1,250, 2,500, and 5,000 mg/kg of body weight, did not cause the death of experimental mice and rats. When administered orally for 30 days at a dose of 2,500 mg/kg of body weight, the disinfectant did not cause any negative and toxic effects on the body of experimental rats, did not affect the growth and development of rats, and did not cause changes in the relative mass of internal organs. It was found that the average manifestation of erythema in rabbits is 2.46. According to the study results, it was found that the disinfectant can be classified as Hazard Class 4 according to the international standard GOST 12.1.007-76, or Category 5 according to the international global classification Global Harmonised System (GHS) (LD50 with oral administration exceeds 5,000 mg/kg of body weight). The results obtained give grounds to assert the possibility of using an experimental disinfectant in the presence of humans and animals

Today there is not enough scientific data on the energy level and the velocity of an explosion in actual mine workings, which have a cross-sectional area larger than experimental mine workings. The objective of the paper is to justify the energy parameters of an explosion in actual mine workings based on the disclosure of the fire front development mechanism when coal dust explodes in an experimental mine working with a limited cross-sectional area. These studies can be the basis for choosing the speed of action and the strength of the means of the localization of dust explosions. The main research method is an experimental and analytical method, based on the analysis of the results of experimental explosions of coal dust in experimental mine workings and theoretical substantiation of the regularities of the development of the velocity and additional energy of the fire front with further extrapolation to the conditions of actual mine workings. It is proposed to supplement the mechanism of explosion development with an idea about the sections of development of explosion dynamics, i.e. initiation, dust explosion, crater, which determine the characteristic parameters of the explosive front velocity: maximum initiating velocity, average velocity, and maximum velocity in a crater. It was established that during methane initiation in the experimental mine working at the boundary between the initiation and dusting zones, there is a situation of a hybrid explosion of a mixture of methane and dust with air, which has its own velocity and energy indicators. A linear dependence of the energy generated during the coal aerosol explosion on the cross-sectional plane of the mine working was established. This makes it possible to use the results of testing the coal from certain deposits in small-scale experimental set-ups to justify the parameters of protective means for the actual mine workings.