49 results on '"Andreyeva, E"'
Search Results
2. System for Preparing Management Decisions: A Gas pipeline siting case study
- Author
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Larichev, O. I., Andreyeva, E. N., Sternin, M. Y., Humphreys, Patrick, editor, Bannon, Liam, editor, McCosh, Andrew, editor, Migliarese, Piero, editor, and Pomerol, Jean-Charles, editor
- Published
- 1996
- Full Text
- View/download PDF
3. Intercalary heterochromatin in polytene chromosomes of Drosophila melanogaster
- Author
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Belyaeva, E. S., Andreyeva, E. N., Belyakin, S. N., Volkova, E. I., and Zhimulev, I. F.
- Published
- 2008
- Full Text
- View/download PDF
4. Local DNA underreplication correlates with accumulation of phosphorylated H2Av in the Drosophila melanogaster polytene chromosomes
- Author
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Andreyeva, E. N., Kolesnikova, T. D., Belyaeva, E. S., Glaser, R. L., and Zhimulev, I. F.
- Published
- 2008
- Full Text
- View/download PDF
5. NDICATORS OF PROFESSIONAL DEFORMATION OF TEACHERS
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Gunina, E. V., primary, Vishnevskaya, M. N., additional, and Andreyeva, E. A., additional
- Published
- 2021
- Full Text
- View/download PDF
6. THE INFLUENCE OF THE LEVEL OF CREATIVITY ON THE CHOICE OF COPING BEHAVIOUR STRATEGIES
- Author
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Andreyeva, E. A., primary and Vishnevskaya, M. N., additional
- Published
- 2021
- Full Text
- View/download PDF
7. EE116 Predicting High-Cost Diabetes Patients: An Analysis of Commercially-Insured Population
- Author
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Zhong, L., Huyan, Y., Andreyeva, E., Smith, M., Han, G., Carpenter, K., Towne, S., Jani, S., Preston, V., and Ory, M.
- Published
- 2023
- Full Text
- View/download PDF
8. Influence of the SuUR gene on intercalary heterochromatin in Drosophila melanogaster polytene chromosomes
- Author
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Zhimulev, I., Belyaeva, E., Makunin, I., Pirrotta, V., Volkova, E., Alekseyenko, A., Andreyeva, E., Makarevich, G., Boldyreva, L., Nanayev, R., and Demakova, O.
- Published
- 2003
- Full Text
- View/download PDF
9. ИНТЕРАКТИВНЫЙ ДИЗАЙН В ПРОИЗВОДСТВЕ МЕХОВОЙ ОДЕЖДЫ
- Author
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Guseva, M, primary, Andreyeva, E, additional, and Alibekova, M, additional
- Published
- 2020
- Full Text
- View/download PDF
10. Immunogold electron microscope localization of proteins in Drosophila polytene chromosomes: applications and limitations of the method
- Author
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Semeshin, V. F., Andreyeva, E. N., Shloma, V. V., Saumweber, H., and Zhimulev, I. F.
- Published
- 2002
11. Non3 is an essential Drosophila gene required for proper nucleolus assembly
- Author
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Andreyeva, E. N., primary, Ogienko, A. A., additional, Yushkova, A. A., additional, Popova, J. V., additional, Pavlova, G. A., additional, Kozhevnikova, E. N., additional, Ivankin, A. V., additional, Gatti, M., additional, and Pindyurin, A. V., additional
- Published
- 2019
- Full Text
- View/download PDF
12. The Release 6 reference sequence of the Drosophila melanogaster genome
- Author
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Hoskins, R, Carlson, J, Wan, K, Park, S, Mendez, I, Galle, S, Booth, B, Pfeiffer, B, George, R, Svirskas, R, Krzywinski, M, Schein, J, Accardo, M, Damia, E, Messina, G, Mendez-Lago, M, De Pablos, B, Demakova, O, Andreyeva, E, Boldyreva, L, Marra, M, Carvalho, A, Dimitri, P, Villasante, A, Zhimulev, I, Rubin, G, Karpen, G, Celniker, S, Hoskins R. A., Carlson J. W., Wan K. H., Park S., Mendez I., Galle S. E., Booth B. W., Pfeiffer B. D., George R. A., Svirskas R., Krzywinski M., Schein J., Accardo M. C., Damia E., Messina G., Mendez-Lago M., De Pablos B., Demakova O. V., Andreyeva E. N., Boldyreva L. V., Marra M., Carvalho A. B., Dimitri P., Villasante A., Zhimulev I. F., Rubin G. M., Karpen G. H., Celniker S. E., Hoskins, R, Carlson, J, Wan, K, Park, S, Mendez, I, Galle, S, Booth, B, Pfeiffer, B, George, R, Svirskas, R, Krzywinski, M, Schein, J, Accardo, M, Damia, E, Messina, G, Mendez-Lago, M, De Pablos, B, Demakova, O, Andreyeva, E, Boldyreva, L, Marra, M, Carvalho, A, Dimitri, P, Villasante, A, Zhimulev, I, Rubin, G, Karpen, G, Celniker, S, Hoskins R. A., Carlson J. W., Wan K. H., Park S., Mendez I., Galle S. E., Booth B. W., Pfeiffer B. D., George R. A., Svirskas R., Krzywinski M., Schein J., Accardo M. C., Damia E., Messina G., Mendez-Lago M., De Pablos B., Demakova O. V., Andreyeva E. N., Boldyreva L. V., Marra M., Carvalho A. B., Dimitri P., Villasante A., Zhimulev I. F., Rubin G. M., Karpen G. H., and Celniker S. E.
- Abstract
Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies of heredity, development, metabolism, behavior, and human disease. The initial reference genome sequence reported more than a decade ago had a profound impact on progress in Drosophila research, and improving the accuracy and completeness of this sequence continues to be important to further progress. We previously described improvement of the 117-Mb sequence in the euchromatic portion of the genome and 21 Mb in the heterochromatic portion, using a whole-genome shotgun assembly, BAC physical mapping, and clone-based finishing. Here, we report an improved reference sequence of the single-copy and middle-repetitive regions of the genome, produced using cytogenetic mapping to mitotic and polytene chromosomes, clone-based finishing and BAC fingerprint verification, ordering of scaffolds by alignment to cDNA sequences, incorporation of other map and sequence data, and validation by whole-genome optical restriction mapping. These data substantially improve the accuracy and completeness of the reference sequence and the order and orientation of sequence scaffolds into chromosome arm assemblies. Representation of the Y chromosome and other heterochromatic regions is particularly improved. The new 143.9-Mb reference sequence, designated Release 6, effectively exhausts clone-based technologies for mapping and sequencing. Highly repeat-rich regions, including large satellite blocks and functional elements such as the ribosomal RNA genes and the centromeres, are largely inaccessible to current sequencing and assembly methods and remain poorly represented. Further significant improvements will require sequencing technologies that do not depend on molecular cloning and that produce very long reads.
- Published
- 2015
13. Social efficiency of the state support of the families having the child aged up to 3 years
- Author
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Andreyeva, E. E. and Morozov, G. B.
- Subjects
CHILD CARE LEAVE ,ПОСОБИЕ ПО УХОДУ ЗА РЕБЕНКОМ ДО 1,5 ЛЕТ ,МИНИМАЛЬНЫЙ РАЗМЕР ОПЛАТЫ ТРУДА ,КОМПЕНСАЦИОННАЯ ВЫПЛАТА ДО ДОСТИЖЕНИЯ РЕБЕНКОМ 3 ЛЕТ ,MINIMUM WAGE ,CHILD CARE ALLOWANCE UP TO 1,5 YEARS ,COMPENSATION PAYMENT BEFORE ACHIEVEMENT OF 3 YEARS BY THE CHILD ,ОТПУСК ПО УХОДУ ЗА РЕБЕНКОМ - Abstract
Оценивается эффективность двух основных видов материальной поддержки российских семей, имеющих ребенка в возрасте до 3 лет: пособие по уходу за ним до 1,5 лет и компенсационная выплата до достижения ребенком 3 лет. В ходе анализа порядка исчисления и размера выплат раскрывается их неэффективность, а в отношении компенсационной выплаты ставится вопрос о нецелесообразности назначения. Выдвигаются предложения законотворческого характера, реализация которых способна решить данную проблему. Efficiency of two main types of material support of the Russian families having the child aged up to 3 years is estimated: a grant on care of him up to 1,5 years and compensation payment before achievement of 3 years by the child. During the analysis of an order of calculation and the amount of payments their inefficiency reveals, and concerning compensation payment the question of inexpediency of appointment is raised. Proposals of legislative character which implementation is capable to solve a dannuyunny problem are made.
- Published
- 2017
14. About influence of higher education institutions on formation of the social portrait of the modern student of the Ural region
- Author
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Myslyakova, Yu. G. and Andreyeva, E. L.
- Subjects
КУЛЬТУРА И СОЦИАЛЬНЫЙ ПОРТРЕТ ,ВУЗЫ ,HIGHER EDUCATION INSTITUTIONS ,CULTURE AND SOCIAL PORTRAIT ,VALUES OF STUDENTS ,СОЦИАЛЬНО-ЦЕННОСТНЫЕ ОРИЕНТИРЫ МОЛОДЕЖИ ,ЦЕННОСТИ СТУДЕНТОВ ,SOCIAL AND VALUABLE REFERENCE POINTS OF YOUTH - Abstract
Данная статья посвящена расширению традиционного понимания роли вузов в формировании личности и ценностных ориентиров молодого поколения. Автор кратко представил результаты опросов студентов ведущих университетов уральского региона и сделал выводы, отражающие способность вузов создавать социальный портрет молодежи, адаптированный к неоиндустриальной картине мира и позволяющий ей успешно существовать в ней. This article is devoted to expansion of traditional understanding of a role of higher education institutions in formation of the personality and valuable reference points of the younger generation. The author briefly presented results of polls of students of leading universities of the Ural region and drew the conclusions reflecting ability of higher education institutions to create the social portrait of youth adapted for a new industrial picture of the world and allowing it to exist successfully in it.
- Published
- 2017
15. Comparative analysis of higher education institutes in Russia and the USA
- Author
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Dyachkova, A. V. and Andreyeva, E. V.
- Subjects
AUTONOMY OF THE UNIVERSITY ,ЭЛИТАРНОЕ ОБРАЗОВАНИЕ ,BOLOGNA PROCESS ,ИНДИВИДУАЛЬНЫЙ ОБРАЗОВАТЕЛЬНЫЙ МАРШРУТ ,UNIVERSITY RATING ,АВТОНОМИЯ УНИВЕРСИТЕТОВ ,ИНДИВИДУАЛИЗАЦИЯ ОБРАЗОВАНИЯ ,БОЛОНСКИЙ ПРОЦЕСС ,ELITIST EDUCATION ,INDIVIDUALIZATION OF EDUCATION ,ПАРТНЕРСТВО ЧАСТНОГО И ГОСУДАРСТВЕННОГО СЕКТОРА ,PARTNERSHIP OF THE PRIVATE AND PUBLIC SECTORS ,INDIVIDUAL EDUCATIONAL ROUTE ,РЕЙТИНГ УНИВЕРСИТЕТОВ ,HIGHER EDUCATION ,ВЫСШЕЕ ОБРАЗОВАНИЕ - Abstract
В статье рассмотрен институт высшего образования в России и США, дан сравнительный анализ высших школ России и США, показано, что российское образование в настоящее время находится в стадии реформирования. The article considers the institute of higher education in Russia and the USA, gives the comparative analysis of the higher education institutions of Russia and the USA; it is shown that Russian education is in the process of reforming.
- Published
- 2017
16. Сравнительный анализ института высшего образования в России и США
- Author
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Дьячкова, А. В., Андреева, Е. В., Dyachkova, A. V., Andreyeva, E. V., Дьячкова, А. В., Андреева, Е. В., Dyachkova, A. V., and Andreyeva, E. V.
- Abstract
В статье рассмотрен институт высшего образования в России и США, дан сравнительный анализ высших школ России и США, показано, что российское образование в настоящее время находится в стадии реформирования., The article considers the institute of higher education in Russia and the USA, gives the comparative analysis of the higher education institutions of Russia and the USA; it is shown that Russian education is in the process of reforming.
- Published
- 2017
17. О влиянии вузов на формирование социального портрета современного студента Уральского региона
- Author
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Мыслякова, Ю. Г., Андреева, Е. Л., Myslyakova, Yu. G., Andreyeva, E. L., Мыслякова, Ю. Г., Андреева, Е. Л., Myslyakova, Yu. G., and Andreyeva, E. L.
- Abstract
Данная статья посвящена расширению традиционного понимания роли вузов в формировании личности и ценностных ориентиров молодого поколения. Автор кратко представил результаты опросов студентов ведущих университетов уральского региона и сделал выводы, отражающие способность вузов создавать социальный портрет молодежи, адаптированный к неоиндустриальной картине мира и позволяющий ей успешно существовать в ней., This article is devoted to expansion of traditional understanding of a role of higher education institutions in formation of the personality and valuable reference points of the younger generation. The author briefly presented results of polls of students of leading universities of the Ural region and drew the conclusions reflecting ability of higher education institutions to create the social portrait of youth adapted for a new industrial picture of the world and allowing it to exist successfully in it.
- Published
- 2017
18. Социальная эффективность государственной поддержки семей, имеющих ребенка в возрасте до 3 лет
- Author
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Андреева, Е. Е., Морозов, Г. Б., Andreyeva, E. E., Morozov, G. B., Андреева, Е. Е., Морозов, Г. Б., Andreyeva, E. E., and Morozov, G. B.
- Abstract
Оценивается эффективность двух основных видов материальной поддержки российских семей, имеющих ребенка в возрасте до 3 лет: пособие по уходу за ним до 1,5 лет и компенсационная выплата до достижения ребенком 3 лет. В ходе анализа порядка исчисления и размера выплат раскрывается их неэффективность, а в отношении компенсационной выплаты ставится вопрос о нецелесообразности назначения. Выдвигаются предложения законотворческого характера, реализация которых способна решить данную проблему., Efficiency of two main types of material support of the Russian families having the child aged up to 3 years is estimated: a grant on care of him up to 1,5 years and compensation payment before achievement of 3 years by the child. During the analysis of an order of calculation and the amount of payments their inefficiency reveals, and concerning compensation payment the question of inexpediency of appointment is raised. Proposals of legislative character which implementation is capable to solve a dannuyunny problem are made.
- Published
- 2017
19. The Release 6 Drosophila melanogaster reference genome
- Author
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Hoskins, R. A., Carlson, J. W., Wan, K. H., Park, S., Mendez, I., Galle, S. E., Booth, B., Pfeiffer1, B. D., George, R. A., Svirskas, R., Krzywinski, M., Schein, J., Accardo, M. C., Damia, E., Messina, Giovanni, Mendez Lago, M., Demakova, O. V., Andreyeva, E. N., Boldyreva, L. V., Marra, M., Carvalho, A. B., Dimitri, Patrizio, Villasante, A., Zhimulev, I. F., Rubin, G. M., Karpen, G. H., and Celniker, S. E.
- Subjects
drosophila genome sequence ,Heterochromatin ,cytogenetic mapping - Published
- 2015
20. Region Foreign Economic Relations as a Factor of Reindustiralization
- Author
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Andreyeva, E. L., Canen, A. G., Ratner, A. V., Zakharova, V. V., Andreyeva, E. L., Canen, A. G., Ratner, A. V., and Zakharova, V. V.
- Abstract
At present, the strengthening vector of the developing economies, in particular, of the countries of Eurasian Economic Union and BRICS, in the geographic structure of Russian foreign economic activity is observed. The subject matter of the article is to see, how the development of this direction can be economically favorable. For this purpose, the forms and degree of the development of economic partnership including collaboration with the Russian regions are investigated. The agreements on the economic partnership with the regions of partner countries of Russia, their production relations are considered. The analysis of foreign trade shows that in the case of the partner countries within Eurasian integration and the BRICS group — Russian economy gets the high possibility to become the supplier of products of relatively high degree of processing which is the key factor of development of its processing industry, i.e. the factor of reindustrialization and export-oriented import substitution.
- Published
- 2015
21. Region Foreign Economic Relations as a Factor of Reindustiralization
- Author
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Andreyeva, E. L., primary, Canen, A. G., additional, Ratner, A. V., additional, and Zakharova, V. V., additional
- Published
- 2015
- Full Text
- View/download PDF
22. Recrystallization of cold-drawn stainless steel
- Author
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Dolinskaya, L. A., Rizol', A. I., Nekrasova, S. Z., and Andreyeva, E. M.
- Published
- 1962
- Full Text
- View/download PDF
23. The estimation of labor life quality in regions of Russia
- Author
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Andreyeva, E. L, primary and Polkova, T. V., additional
- Published
- 2013
- Full Text
- View/download PDF
24. In vitro accumulation of the photosensitizer Photosens in the atherosclerotic plaque of the human carotid artery
- Author
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Efremova, Yu E., Andreyeva, E. R., Soboleva, G. N., Natalya Radyukhina, Beloyartsev, D. F., Karpov, Yu A., and Tararak, E. M.
25. Molecular biological features of the ectopic and eutopic endometrium in genital endometriosis
- Author
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Zairatyants, O. V., Adamyan Leila, Andreyeva, E. N., Maksimova, Yu V., Murdalova, Z. Kh, Opalenov, K. V., Movtayeva, R. Kh, Sonova, M. M., and Zarubtna, I. P.
26. Cognitive development in children with brain tumors
- Author
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Voronin, N. A., Burdukova, Yu A., Gniteyeva, L. N., Popov, V. E., Andreyeva, E. V., and Tatiana Stroganova
27. EPH125 Geographic Disparities in Chronic Kidney Disease Hospitalizations: Exploring Associations with Neighborhood Socioeconomic Status in Texas.
- Author
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Zhong, L, Farej, R, Andreyeva, E, Farag, Y, Singh, R, Kong, SX, Sorescu, A, Ma, P, Du, Y, Udeani, G, Guerrero, G, Ohsfeldt, RL, Young, J, Cameron, J, and Williamson, T
- Published
- 2024
- Full Text
- View/download PDF
28. The Release 6 reference sequence of the Drosophila melanogaster genome
- Author
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Ivonne Mendez, Maria Mendez-Lago, Alfredo Villasante, Lidiya V. Boldyreva, Joseph W. Carlson, Kenneth H. Wan, Jacqueline E. Schein, Benjamin W. Booth, Reed A. George, Evgeniya N. Andreyeva, Gary H. Karpen, Patrizio Dimitri, Maria Carmela Accardo, A. Bernardo Carvalho, Robert Svirskas, Marco A. Marra, Soo Park, Martin Krzywinski, Elisabetta Damia, Olga V. Demakova, Giovanni Messina, Beatriz de Pablos, Igor F. Zhimulev, Gerald M. Rubin, Roger A. Hoskins, Samuel E. Galle, Susan E. Celniker, Barret D. Pfeiffer, Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro, Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil), Fondazione Cenci Bolognetti, University of California, Ministry of Education and Science of the Russian Federation, Ministerio de Economía y Competitividad (España), Hoskins, R, Carlson, J, Wan, K, Park, S, Mendez, I, Galle, S, Booth, B, Pfeiffer, B, George, R, Svirskas, R, Krzywinski, M, Schein, J, Accardo, M, Damia, E, Messina, G, Mendez-Lago, M, De Pablos, B, Demakova, O, Andreyeva, E, Boldyreva, L, Marra, M, Carvalho, A, Dimitri, P, Villasante, A, Zhimulev, I, Rubin, G, Karpen, G, and Celniker, S
- Subjects
Resource ,Chromosomes, Artificial, Bacterial ,Sequence analysis ,Bioinformatics ,Restriction Mapping ,Molecular Sequence Data ,Drosophila, Genome ,Sequence assembly ,Computational biology ,Biology ,Genome ,Medical and Health Sciences ,Contig Mapping ,Chromosomes ,Fluorescence ,03 medical and health sciences ,0302 clinical medicine ,Restriction map ,Genetics ,Animals ,In Situ Hybridization, Fluorescence ,Genetics (clinical) ,In Situ Hybridization ,030304 developmental biology ,Sequence (medicine) ,Polytene Chromosomes ,0303 health sciences ,Human Genome ,Bacterial ,Chromosome Mapping ,Computational Biology ,High-Throughput Nucleotide Sequencing ,Genome project ,Biological Sciences ,Drosophila melanogaster ,Artificial ,Generic health relevance ,030217 neurology & neurosurgery ,Reference genome ,Biotechnology - Abstract
Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies of heredity, development, metabolism, behavior, and human disease. The initial reference genome sequence reported more than a decade ago had a profound impact on progress in Drosophila research, and improving the accuracy and completeness of this sequence continues to be important to further progress. We previously described improvement of the 117-Mb sequence in the euchromatic portion of the genome and 21 Mb in the heterochromatic portion, using a whole-genome shotgun assembly, BAC physical mapping, and clone-based finishing. Here, we report an improved reference sequence of the single-copy and middle-repetitive regions of the genome, produced using cytogenetic mapping to mitotic and polytene chromosomes, clone-based finishing and BAC fingerprint verification, ordering of scaffolds by alignment to cDNA sequences, incorporation of other map and sequence data, and validation by whole-genome optical restriction mapping. These data substantially improve the accuracy and completeness of the reference sequence and the order and orientation of sequence scaffolds into chromosome arm assemblies. Representation of the Y chromosome and other heterochromatic regions is particularly improved. The new 143.9-Mb reference sequence, designated Release 6, effectively exhausts clone-based technologies for mapping and sequencing. Highly repeat-rich regions, including large satellite blocks and functional elements such as the ribosomal RNA genes and the centromeres, are largely inaccessible to current sequencing and assembly methods and remain poorly represented. Further significant improvements will require sequencing technologies that do not depend on molecular cloning and that produce very long reads., This work was supported by NIH grants P50 HG00750 (G.M.R.), R01 HG00747 (G.H.K.), and R01 HG002673 (S.E.C.) and performed under U.S. Department of Energy Contracts DE-AC0376SF00098 and DE-AC02-05CH11231, University of California. I.F.Z. was supported by grant 13-04-40137 from the Russian Federation; E.N.A. was supported by grant 12-04-00874-a from the Russian Federation; P.D. was supported by a grant from the Instituto Pasteur-Fondazione Cenci Bolognetti; A.V. was supported by Ministerio de Economía y Competitividad grant BFU2011-30295-C02-01; and A.B.C. was supported by NIH grant R01 GM064590 and grants from Fundaçao de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ) and the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).
- Published
- 2015
- Full Text
- View/download PDF
29. Assessing the Readiness of Rural Public Librarians to Implement Public Health Programs.
- Author
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Lenstra N, Franklin H, Dieckmann NF, Andreyeva E, Maddock J, Seguin-Fowler RA, Winkle J, and Perry CK
- Abstract
Although health promotion is not the primary function of public libraries, it is well documented that many libraries engage in health promotion activities, even when resources are constrained. Less understood is the readiness of the public library workforce, particularly in rural communities, to implement evidence-based health promotion programs. This study uses a modified version of the Competency Assessment for Tier 2 Public Health Professionals to assess the readiness of a small sample (n = 21) of Oregon rural library managers to implement evidence-based health initiatives. Results show that outside of communication skills, most rural library workers do not consider themselves to have proficiency in core health promotion competencies. Although some slight differences were found among librarians based on socio-demographic factors, those differences were not statistically significant. Implications include the need for strengthened support to build the capacity for rural public library workers who are interested in delivering evidence-based health promotion programs., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
30. Examining the impact of Medicaid payments for immediate postpartum long-acting reversible contraception on the mental health of low-income mothers.
- Author
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Marthey D, Rochford H, and Andreyeva E
- Subjects
- Humans, United States, Female, Adult, Adolescent, Young Adult, Behavioral Risk Factor Surveillance System, Mothers psychology, Mothers statistics & numerical data, Medicaid statistics & numerical data, Medicaid economics, Long-Acting Reversible Contraception statistics & numerical data, Long-Acting Reversible Contraception economics, Poverty, Mental Health, Postpartum Period
- Abstract
Objective: To examine the effect of Medicaid immediate postpartum long-acting reversible contraception (IPP LARC) reforms on self-reported mental health among low-income mothers aged 18-44 years., Data Sources and Study Setting: We used national secondary data on self-reported mental health status in the past 30 days from the core component (2014-2019) of the Behavioral Risk Factor Surveillance System (BRFSS)., Study Design: We estimated linear probability models for reporting any days of not good mental health in the past 30 days. We adjusted for individual-level factors, state-level factors, and state and year fixed effects. Our primary independent variable was an indicator for IPP LARC payment reform. We examined the effect of the Medicaid payment reforms on self-reported mental health status in the past 30 days using difference-in-differences and event-study designs., Data Collection/extraction Methods: Not applicable., Principal Findings: State adoption of Medicaid IPP LARC reforms was associated with significant reductions (between 5.7% and 11.5%) in the predicted probability of reporting any days of not good mental health among low-income mothers. Treatment effects appeared to be driven by respondents reporting two or more children (less than 18 years of age) in the household (ATT = -0.028, p = 0.04). Results are robust to a series of sensitivity tests and alternative estimation strategies., Conclusions: Our findings suggest that contemporary efforts to improve access to contraceptive methods may have important benefits beyond reproductive autonomy. These findings have implications for policymakers as the landscape related to family planning services continues to shift., (© 2024 The Authors. Health Services Research published by Wiley Periodicals LLC on behalf of Health Research and Educational Trust.)
- Published
- 2024
- Full Text
- View/download PDF
31. Examining Health Inequities in A1C Control over Time across Individual, Geospatial, and Geopolitical Factors among Adults with Type 2 Diabetes: Analyses of a Sample from One Commercial Insurer in a Southern State.
- Author
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Towne SD Jr, Ory MG, Zhong L, Smith ML, Han G, Andreyeva E, Carpenter K, Ahn S, and Preston VA
- Subjects
- Humans, Male, Middle Aged, Female, Texas epidemiology, Adult, Aged, Health Inequities, Healthcare Disparities, Diabetes Mellitus, Type 2 epidemiology, Glycated Hemoglobin analysis
- Abstract
Introduction: Type 2 diabetes impacts millions and poor maintenance of diabetes can lead to preventable complications, which is why achieving and maintaining target A1C levels is critical. Thus, we aimed to examine inequities in A1C over time, place, and individual characteristics, given known inequities across these indicators and the need to provide continued surveillance., Methods: Secondary de-identified data from medical claims from a single payer in Texas was merged with population health data. Generalized Estimating Equations were utilized to assess multiple years of data examining the likelihood of having non-target (>7% and ≥7%, two slightly different cut points based on different sources) and separately uncontrolled (>9%) A1C. Adults in Texas, with a Type 2 Diabetes (T2D) flag and with A1C reported in first quarter of the year using data from 2016 and 2019 were included in analyses., Results: Approximately 50% had A1Cs within target ranges (<7% and ≤7%), with 50% considered having non-target (>7% and ≥7%) A1Cs; with 83% within the controlled ranges (≤9%) as compared to approximately 17% having uncontrolled (>9%) A1Cs. The likelihood of non-target A1C was higher among those individuals residing in rural (vs urban) areas ( P < .0001); similar for the likelihood of reporting uncontrolled A1C, where those in rural areas were more likely to report uncontrolled A1C ( P < .0001). In adjusted analysis, ACA enrollees in 2016 were approx. 5% more likely (OR = 1.049, 95% CI = 1.002-1.099) to have non-target A1C (≥7%) compared to 2019; in contrast non-ACA enrollees were approx. 4% more likely to have non-target A1C (≥7%) in 2019 compared to 2016 (OR = 1.039, 95% CI = 1.001-1.079). In adjusted analysis, ACA enrollees in 2016 were 9% more likely (OR = 1.093, 95% CI = 1.025-1.164) to have uncontrolled A1C compared to 2019; whereas there was no significant change among non-ACA enrollees., Conclusions: This study can inform health care interactions in diabetes care settings and help health policy makers explore strategies to reduce health inequities among patients with diabetes. Key partners should consider interventions to aid those enrolled in ACA plans, those in rural and border areas, and who may have coexisting health inequities., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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32. Merging Rural And Urban ACA Rating Areas Improved Choice, Premiums In Rural Texas.
- Author
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Haeder SF, Andreyeva E, Marthey D, and Ukert BD
- Subjects
- Humans, United States, Texas, Rural Population, Insurance, Health, Insurance Coverage, Patient Protection and Affordable Care Act, Health Insurance Exchanges
- Abstract
Rural consumers often face a limited choice of carriers and plans and high premiums. To mitigate this issue, Texas recently adjusted its Affordable Care Act Marketplace rating areas to integrate rural areas into nearby urban markets for rating purposes. We found that rural consumers subsequently saw increases in carrier and plan choices, as well as decreases in overall plan premiums.
- Published
- 2023
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33. Group-based trajectory analysis identifies varying diabetes-related cost trajectories among type 2 diabetes patients in Texas: an empirical study using commercial insurance.
- Author
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Han G, Spencer MS, Ahn S, Smith ML, Zhong L, Andreyeva E, Carpenter K, Towne SD Jr, Preston VA, and Ory MG
- Subjects
- Humans, Texas epidemiology, Glycated Hemoglobin, Diabetes Mellitus, Type 2, Diabetes Complications, Insurance
- Abstract
Background: The trend of Type 2 diabetes-related costs over 4 years could be classified into different groups. Patient demographics, clinical factors (e.g., A1C, short- and long-term complications), and rurality could be associated with different trends of cost. Study objectives are to: (1) understand the trajectories of cost in different groups; (2) investigate the relationship between cost and key factors in each cost trajectory group; and (3) assess significant factors associated with different cost trajectories., Methods: Commercial claims data in Texas from 2016 to 2019 were provided by a large commercial insurer and were analyzed using group-based trajectory analysis, longitudinal analysis of cost, and logistic regression analyses of different trends of cost., Results: Five groups of distinct trends of Type 2 diabetes-related cost were identified. Close to 20% of patients had an increasing cost trend over the 4 years. High A1C values, diabetes complications, and other comorbidities were significantly associated with higher Type 2 diabetes costs and higher chances of increasing trend over time. Rurality was significantly associated with higher chances of increasing trend over time., Conclusions: Group-based trajectory analysis revealed distinct patient groups with increased cost and stable cost at low, medium, and high levels in the 4-year period. The significant associations found between the trend of cost and A1C, complications, and rurality have important policy and program implications for potentially improving health outcomes and constraining healthcare costs., (© 2023. BioMed Central Ltd., part of Springer Nature.)
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- 2023
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34. Rural libraries implementing walking groups or walking groups plus civic engagement for walkability in rural communities: a comparative effectiveness trial study protocol.
- Author
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Perry CK, Seguin-Fowler R, Maddock JE, Lenstra N, Dieckmann NF, Currier J, Andreyeva E, Winkle J, and Trost SG
- Subjects
- Adult, Humans, Exercise, Health Promotion methods, Health Behavior, Randomized Controlled Trials as Topic, Rural Population, Walking
- Abstract
Background: Rural residents generally lack adequate physical activity to benefit health and reduce disparities in chronic diseases, such as cardiovascular disease and certain cancers. The Socioecological Model describes physical activity as involving a dynamic and reciprocal interaction between individual, social, and community factors. Community group-based walking programs and civic engagement interventions aimed at enhancing physical activity have been successful in rural communities but have not targeted all three socioecological levels. Public libraries can act as innovative public health partners in rural communities. However, challenges remain because rural libraries often lack the capacity to implement evidence-based health promotion programming. The goals of this study are (1) build the capacity for rural libraries to implement evidence-based health promotion programs, (2) compare changes in physical activity between a group-based walking program and a combined group-based walking and civic engagement program with rural residents, and (3) conduct an implementation evaluation., Methods: We will conduct a comparative effectiveness study of a group-based walking (standard approach) versus a group-based walking plus civic engagement program (combined approach) aimed at enhancing walkability to increase physical activity among rural adults. Key mediators between the program effects and change in outcomes will also be identified. Finally, we will evaluate program implementation, conduct a cost effectiveness evaluation, and use a positive deviance analysis to understand experiences of high and low changers on key outcomes. Twenty towns will be matched and randomized to one of the two conditions and our aim is to enroll a total of 350-400 rural residents (15-20 per town). Study outcomes will be assessed at baseline, and 6, 12, and 24 months., Discussion: This study will build the capacity of rural libraries to implement evidence-based walking programs as well as other health promotion programs in their communities. The study results will answer questions regarding the relative effectiveness and cost effectiveness of two multilevel physical activity interventions targeting rural communities. We will learn what works and how these multilevel interventions can be implemented in rural populations., Trial Registration: ClinicalTrials.gov Identifier: NCT05677906., (© 2023. BioMed Central Ltd., part of Springer Nature.)
- Published
- 2023
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35. Factors associated with higher hemoglobin A1c and type 2 diabetes-related costs: Secondary data analysis of adults 18 to 64 in Texas with commercial insurance.
- Author
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Ory MG, Han G, Jani SN, Zhong L, Andreyeva E, Carpenter K, Towne SD Jr, Preston VA, and Smith ML
- Subjects
- Adult, Male, Humans, Female, Glycated Hemoglobin, Secondary Data Analysis, Texas epidemiology, Diabetes Mellitus, Type 2 epidemiology, Insurance
- Abstract
Objective: This study will identify factors associated with higher hemoglobin A1c (A1c) values and diabetes-related costs among commercially insured adults in Texas diagnosed with type 2 diabetes., Research Design and Methods: This secondary data analysis was based on claims data from commercially insured individuals 18-64 years of age residing in Texas with diagnosed type 2 diabetes during the 2018-2019 study period. The final analysis sample after all the exclusions consisted of 34,992 individuals. Measures included hemoglobin A1c, diabetes-related costs, Charlson Comorbidity Index, diabetes-related complications, rurality and other socioeconomic characteristics. Longitudinal A1c measurements were modeled using age, sex, rurality, comorbidity, and diabetes-related complications in generalized linear longitudinal regression models adjusting the observation time, which was one of the 8 quarters in 2018 and 2019. The diabetes-related costs were similarly modeled in both univariable and multivariable generalized linear longitudinal regression models adjusting the observation time by calendar quarters and covariates., Results: The median A1c value was 7, and the median quarterly diabetes-related cost was $120. A positive statistically significant relationship (p = < .0001) was found between A1c levels and diabetes-related costs, although this trend slowed down as A1c levels exceeded 8.0%. Higher A1c values were associated with being male, having diabetes-related complications, and living in rural areas. Higher costs were associated with higher A1c values, older age, and higher Charlson Comorbidity Index scores., Conclusion: The study adds updated analyses of the interrelationships among demographic and geographic factors, clinical indicators, and health-related costs, reinforcing the role of higher A1c values and complications as diabetes-related cost drivers., Competing Interests: The commercial affiliation for Dr. Preston was declared as she was employed by a commercial company at the time this manuscript was prepared., (Copyright: © 2023 Ory et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
- Published
- 2023
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36. Social determinants of health and high-cost utilization among commercially insured population.
- Author
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Andreyeva E, Chi W, Zhang Y, Kaushal R, and Haynes K
- Subjects
- Adult, Child, Humans, Social Determinants of Health
- Abstract
Objectives: To assess the impact of adding neighborhood social determinants of health (SDOH) data to demographic and clinical characteristics for predicting high-cost utilizers and to examine variations across age groups., Study Design: Using US Census data and 2017-2018 commercial claims from a large national insurer, we estimated association between neighborhood-level SDOH and the probability of being a high-cost utilizer., Methods: Observational study using administrative claims from a national insurer and US Census data. Data included a 50% random sample of commercially insured individuals who were younger than 89 years and had 1 year of continuous eligibility in 2017 and at least 30 days in 2018. Probit models assessed impact of SDOH and neighborhood conditions on predicting cost status., Results: SDOH did not improve predictive power of evaluated models. However, disadvantaged neighborhood residence was still associated with being a high-cost utilizer. Adults 65 years and older in disadvantaged neighborhoods had increased likelihood of high-cost utilization. Children and younger adults in disadvantaged neighborhoods had lower risk of becoming high-cost utilizers., Conclusions: Policy makers and industry stakeholders should be aware of the mechanisms behind the relationship between neighborhood social conditions and health outcomes and how the relationship differs across age groups.
- Published
- 2023
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37. Laparoscopic cyst enucleation is a promising technique for treatment of gastrointestinal tract duplications in children.
- Author
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Shchapov N, Kulikov D, Ekimovskaya E, Sergeyeva S, Andreyeva E, and Ivanitskaya O
- Subjects
- Humans, Child, Gastrointestinal Tract, Intestines, Postoperative Complications epidemiology, Postoperative Complications etiology, Treatment Outcome, Retrospective Studies, Laparoscopy methods, Cysts surgery, Cysts etiology
- Abstract
Background: Laparoscopic cyst enucleation has its advantages and limitations in treatment of gastrointestinal tract (GIT) duplications. It allows to avoid bowel resection in such locations as ileocecal valve. We introduced laparoscopic cyst enucleation with further bowel plasty using cyst muscle layer and without monopolar coagulation, for cyst dissection we used straight scissors., Materials and Methods: Our study included 20 children with GIT duplications, who underwent cyst enucleation from 2018 to 2021. Laparoscopy was performed in all cases with various cyst locations (stomach - 2, duodenum - 3, small bowel - 14, ileocecal area - 1). Mean age of surgery was 40 ± 35,3 days (min 6 days, max 150 days)., Results: Mean operation time was 84,4 ± 27,35 min (min - 40 min, max - 160 min). We had no intraoperative complications. All patients received parenteral feeding for 3-5 days after the operation. Postoperative complications occurred in 3 cases: bowel perforation which required enterostomy (10%) and bowel volvulus required resection (5%). To our opinion, perforations occurred due to monopolar coagulation used for cyst enucleation in these children. No complications were observed in patients who underwent enucleation by straight scissors. Mean postoperative hospital stay was 15.6 ± 10.48 days (min - 4 days, max - 58 days). We observed neither stenosis nor any other complications in the long-term follow-up., Conclusions: Laparoscopic cyst enucleation is a feasible and safe approach for GIT duplications. It allows to avoid bowel resection, and the use of straight scissors instead of monopolar coagulation provides less postoperative complications such as perforation., The Level of Evidence: III., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2023
- Full Text
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38. Nursing turnover in a large, rural health system.
- Author
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Andreyeva E, David G, Griese E, Stansbury Ward C, and Candon M
- Subjects
- Humans, Personnel Turnover, Workforce, Hospitals, Rural, Rural Health, Rural Population
- Abstract
Purpose: Nursing turnover is a leading cause of inefficiency in health care delivery. Few studies have examined turnover among nurses who work in rural areas., Methods: We accessed human resources data that tracked hiring and terminations from a large health system operating in South Dakota, North Dakota, and Minnesota between January 2016 and December 2017. Our study sample included 7,634 registered nurses, 1,765 of whom worked in a rural community. Within the health system, there were 27 affiliated hospitals, 17 of which were designated critical access hospitals. We estimated nursing turnover rates overall and stratified turnover rates by available demographic and occupational characteristics, including whether the nurse worked in a community with an affiliated acute care hospital or critical access hospital., Findings: Overall, 19% of nurses left their position between January 2016 and December 2017. Turnover rates were associated with state, nurse gender and age, and occupational tenure, but were similar in urban and rural areas. Of note, turnover rates were significantly higher in communities without an affiliated acute care hospital or critical access hospital., Conclusion: Between 2016 and 2017, nearly 1 in 5 nurses working in this health system left their position. Turnover rates differed based on nurse demographics and selected occupational characteristics, including tenure. We also found higher turnover rates among nurses who worked in communities without an affiliated hospital, which points to a potential but unexplored benefit of hospitals in rural areas., (© 2022 National Rural Health Association.)
- Published
- 2023
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39. Rural Hospital Closures: Effects on Utilization and Medical Spending Among Commercially Insured Individuals.
- Author
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Andreyeva E, Kash B, Averhart Preston V, Vu L, and Dickey N
- Subjects
- Aged, Emergency Service, Hospital, Health Services Accessibility, Humans, Medicare, Rural Population, United States, Health Facility Closure, Hospitals, Rural
- Abstract
Background: Access to health care continues to be a challenge, especially in remote areas. Since 2013, 70 rural hospitals have closed in the United States further exacerbating barriers to health care access in rural areas., Objective: The objective of this study is to identify the impact of rural hospital closures on total medical spending and utilization among the commercially insured rural population., Research Design: We use a pre-post study design with a comparison group. Individual-level Texas commercial claims data in 2014-2019 were linked to the Centers for Medicare & Medicaid Services (CMS) Provider of Services Current Files, Area Health Resource File, and Census American Community Survey. We performed an event study to test for pre-trends., Subjects: Analysis sample included commercially insured individuals 19-64 years of age residing in Texas., Measures: Total medical spending and counts of health care encounters., Results: Individuals residing in rural Texas areas affected by a hospital closure experienced decreases in outpatient and emergency department (ED) utilization and no statistically significant changes in total medical spending relative to the unaffected individuals. Outpatient and ED utilization decreased by 0.133 (<0.1) and 0.015 (7<0.05) visits, respectively. Heterogeneity analysis showed that individuals residing in urban Texas experienced increases in total medical spending by $12.2 per month (<0.01) as well as individual spending subcategories., Conclusions: Rural hospital closures led to significant decreases in outpatient and ED utilization while having no effect on health care spending. Close attention must be paid to rural hospital closures to ensure equitable health care access, especially for underserved populations., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
40. Frequency and factors associated with foregone and delayed medical care due to COVID-19 among nonelderly US adults from August to December 2020.
- Author
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Giannouchos TV, Brooks JM, Andreyeva E, and Ukert B
- Subjects
- Adult, Aged, Health Services Accessibility, Health Status, Humans, Pandemics, Patient Care, SARS-CoV-2, United States epidemiology, COVID-19
- Abstract
Objectives: To estimate the frequency and factors associated with foregone and delayed medical care attributed to the COVID-19 pandemic among nonelderly adults from August to December 2020 in the United States., Methods: We used three survey waves from the Urban Institute's Household Pulse Survey (HPS) collected between August 19-31, October 14-26 and December 9-21. The final sample included 155,825 nonelderly (18-64) respondents representing 135,835,598 million individuals in the United States. We used two multivariable logistic regressions to estimate the association between respondents' characteristics and foregone and delayed care., Results: The frequency of foregone and delayed medical care was 26.9% and 35.9%, respectively. Around 60% of respondents reported difficulties in paying for usual household expenses in the last 7 days. More than half reported several days of mental health issues. The regression results indicated that foregone or delayed care were significantly associated with difficulties in paying usual household expenses (p < 0.001), worse self-reported health status (p < 0.001), increased mental health problems (p < 0.001), Veterans Affairs (p <0.001) or Medicaid (p = 0.003) coverage compared to private healthcare coverage, and older age groups. Individuals who participated in the latter two waves of the survey (October, December) were less likely to report foregone and delayed care compared to those who participated in Wave 1 (August)., Conclusion: Overall, the frequency of foregone and delayed medical care remained high from August to December 2020 among nonelderly US adults. Our findings highlight that pandemic-induced access barriers are major drivers of reduced healthcare provision during the second half of the pandemic and highlight the need for policies to support patients in seeking timely care., (© 2021 John Wiley & Sons Ltd.)
- Published
- 2022
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41. Neighborhood-level Social Determinants of Health Improve Prediction of Preventable Hospitalization and Emergency Department Visits Beyond Claims History.
- Author
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Chi W, Andreyeva E, Zhang Y, Kaushal R, and Haynes K
- Subjects
- Emergency Service, Hospital, Hospitalization, Humans, Prospective Studies, Ambulatory Care Sensitive Conditions, Social Determinants of Health
- Abstract
This study was conducted to assess if neighborhood-level social determinants of health improve model performance of predicting preventable hospitalization. Using medical and pharmacy claims and neighborhood-level social determinants and the split sample method (67% training with balanced sample and 33% validation), the authors developed prospective modeling for preventable hospital use, defined as hospitalization for ambulatory care sensitive conditions (Agency for Healthcare Research and Quality Prevention Quality Indicators 90 and 92) and preventable emergency department (ED) use (based on Billing's algorithm). Performance of age-gender only or age-gender with administrative claims models were compared to models with the addition of social determinants. Adding social determinants to age-gender only models and claim history models improves model performance as measured by Brier score, C statistics, and area under the precision-recall curve for preventable ED use measures while it leads to similar performance for predicting preventable hospital use compared to models without social determinants. Adding neighborhood-level social determinants improved prediction for preventable ED use in the absence of individual-level social determinants, regardless of the availability of full administrative claims history.
- Published
- 2021
- Full Text
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42. Trends in outpatient emergency department visits during the COVID-19 pandemic at a large, urban, academic hospital system.
- Author
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Giannouchos TV, Biskupiak J, Moss MJ, Brixner D, Andreyeva E, and Ukert B
- Subjects
- Adolescent, Adult, COVID-19, Cross-Sectional Studies, Female, Hospitals, Teaching, Hospitals, Urban, Humans, Male, Retrospective Studies, Utah, Young Adult, Ambulatory Care statistics & numerical data, Ambulatory Care trends, Emergency Service, Hospital statistics & numerical data, Emergency Service, Hospital trends, Facilities and Services Utilization statistics & numerical data
- Abstract
Background: The coronavirus disease 2019 (COVID-19) pandemic has critically affected healthcare delivery in the United States. Little is known on its impact on the utilization of emergency department (ED) services, particularly for conditions that might be medically urgent. The objective of this study was to explore trends in the number of outpatient (treat and release) ED visits during the COVID-19 pandemic., Methods: We conducted a cross-sectional, retrospective study of outpatient emergency department visits from January 1, 2019 to August 31, 2020 using data from a large, urban, academic hospital system in Utah. Using weekly counts and trend analyses, we explored changes in overall ED visits, by patients' area of residence, by medical urgency, and by specific medical conditions., Results: While outpatient ED visits were higher (+6.0%) in the first trimester of 2020 relative to the same period in 2019, the overall volume between January and August of 2020 was lower (-8.1%) than in 2019. The largest decrease occurred in April 2020 (-30.4%), followed by the May to August period (-12.8%). The largest declines were observed for visits by out-of-state residents, visits classified as non-emergent, primary care treatable or preventable, and for patients diagnosed with hypertension, diabetes, headaches and migraines, mood and personality disorders, fluid and electrolyte disorders, and abdominal pain. Outpatient ED visits for emergent conditions, such as palpitations and tachycardia, open wounds, syncope and collapse remained relatively unchanged, while lower respiratory disease-related visits were 67.5% higher in 2020 relative to 2019, particularly from March to April 2020. However, almost all types of outpatient ED visits bounced back after May 2020., Conclusions: Overall outpatient ED visits declined from mid-March to August 2020, particularly for non-medically urgent conditions which can be treated in other more appropriate care settings. Our findings also have implications for insurers, policymakers, and other stakeholders seeking to assist patients in choosing more appropriate setting for their care during and after the pandemic., Competing Interests: Declaration of Competing Interest All authors report not conflict of interest., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2021
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43. The Impact of Medical Marijuana Laws and Dispensaries on Self-Reported Health.
- Author
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Andreyeva E and Ukert B
- Subjects
- Adult, Alcohol Drinking, Body Weight, Female, Humans, Male, Middle Aged, Smoking, United States, Young Adult, Health Status, Marijuana Use legislation & jurisprudence, Medical Marijuana
- Abstract
Growing evidence suggests that medical marijuana laws have harm reduction effects across a variety of outcomes related to risky health behaviors. This study investigates the impact of medical marijuana laws on self-reported health using data from the Behavioral Risk Factor Surveillance System from 1993 to 2013. In our analyses we separately identify the effect of a medical marijuana law and the impact of subsequent active and legally protected dispensaries. Our main results show surprisingly limited improvements in self-reported health after the legalization of medical marijuana and legally protected dispensaries. Subsample analyses reveal strong improvements in health among non-white individuals, those reporting chronic pain, and those with a high school degree, driven predominately by whether or not the state had active and legally protected dispensaries. We also complement the analysis by evaluating the impact on risky health behaviors and find that the aforementioned demographic groups experience large reductions in alcohol consumption after the implementation of a medical marijuana law.
- Published
- 2019
- Full Text
- View/download PDF
44. Naloxone Availability and Pharmacy Staff Knowledge of Standing Order for Naloxone in Pennsylvania Pharmacies.
- Author
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Graves RL, Andreyeva E, Perrone J, Shofer FS, Merchant RM, and Meisel ZF
- Subjects
- Health Expenditures statistics & numerical data, Health Services Accessibility, Humans, Naloxone economics, Narcotic Antagonists economics, Nonprescription Drugs economics, Nonprescription Drugs supply & distribution, Opioid-Related Disorders economics, Opioid-Related Disorders rehabilitation, Pennsylvania, Pharmaceutical Services, Pharmacies economics, Prescription Drugs economics, Prescription Drugs supply & distribution, Health Knowledge, Attitudes, Practice, Naloxone supply & distribution, Narcotic Antagonists supply & distribution, Pharmacies statistics & numerical data, Standing Orders
- Abstract
Objective: To assess the availability and price of naloxone as well as pharmacy staff knowledge of the standing order for naloxone in Pennsylvania pharmacies., Methods: We conducted a telephone audit study from December 2016 to April 2017 in which staff from Pennsylvania pharmacies were surveyed to evaluate naloxone availability, staff understanding of the naloxone standing order, and out-of-pocket cost of naloxone., Results: Responses were obtained from 682 of 758 contacted pharmacies (90% response rate). Naloxone was stocked (ie, available for dispensing) in 306 (45%) pharmacies surveyed. Of the 376 (55%) pharmacies that did not stock naloxone, 118 (31%) stated that they could place an order for naloxone for pickup within 1 business day. Responses by pharmacy staff to questions about key components of the standing order for naloxone were collected from 581 of the 682 pharmacies who participated in the survey (85%). Of the 581 pharmacy staff members who stated that they either stocked or could order naloxone, 64% correctly answered all questions pertaining to understanding of the naloxone standing order. The respective median out-of-pocket prices stated in the audit varied by formulation and ranged from $50 to $4000. Staff from national pharmacies were significantly more likely than staff from regional/local chain and non-chain pharmacies to correctly answer that a prescription was not required to obtain naloxone (68.5%, 57.7%, and 52.4% respectively, (P = 0.0045)., Conclusions: Multiple barriers to naloxone access exist in pharmacies across a large, diverse state, despite the presence of a standing order to facilitate such access. Limited availability of naloxone in pharmacies, lack of knowledge or understanding by pharmacy staff of the standing order, and variability in out-of-pocket cost for this drug are among these potential barriers. Regulatory or legal incentives for pharmacies or drug manufacturers, education efforts directed toward pharmacy staff members, or other interventions may be needed to increase naloxone availability in pharmacies.
- Published
- 2019
- Full Text
- View/download PDF
45. The impact of the minimum wage on health.
- Author
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Andreyeva E and Ukert B
- Subjects
- Adult, Age Factors, Alcohol Drinking epidemiology, Behavioral Risk Factor Surveillance System, Body Mass Index, Diet, Humans, Middle Aged, Models, Economic, Obesity epidemiology, Smoking epidemiology, Socioeconomic Factors, United States, Health Behavior, Health Services Accessibility statistics & numerical data, Health Status, Income statistics & numerical data
- Abstract
This study evaluates the effect of minimum wage on risky health behaviors, healthcare access, and self-reported health. We use data from the 1993-2015 Behavioral Risk Factor Surveillance System, and employ a difference-in-differences strategy that utilizes time variation in new minimum wage laws across U.S. states. Results suggest that the minimum wage increases the probability of being obese and decreases daily fruit and vegetable intake, but also decreases days with functional limitations while having no impact on healthcare access. Subsample analyses reveal that the increase in weight and decrease in fruit and vegetable intake are driven by the older population, married, and whites. The improvement in self-reported health is especially strong among non-whites, females, and married.
- Published
- 2018
- Full Text
- View/download PDF
46. Neighborhood Interventions to Reduce Violence.
- Author
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Kondo MC, Andreyeva E, South EC, MacDonald JM, and Branas CC
- Subjects
- Alcoholic Beverages supply & distribution, Crime prevention & control, Housing standards, Humans, Poverty statistics & numerical data, Built Environment standards, Residence Characteristics statistics & numerical data, Violence prevention & control
- Abstract
Violence is a widespread problem that affects the physical, mental, and social health of individuals and communities. Violence comes with an immense economic cost to its victims and society at large. Although violence interventions have traditionally targeted individuals, changes to the built environment in places where violence occurs show promise as practical, sustainable, and high-impact preventive measures. This review examines studies that use quasi-experimental or experimental designs to compare violence outcomes for treatment and control groups before and after a change is implemented in the built environment. The most consistent evidence exists in the realm of housing and blight remediation of buildings and land. Some evidence suggests that reducing alcohol availability, improving street connectivity, and providing green housing environments can reduce violent crimes. Finally, studies suggest that neither transit changes nor school openings affect community violence.
- Published
- 2018
- Full Text
- View/download PDF
47. Firearm Violence as a Disease-"Hot People" or "Hot Spots"?
- Author
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Branas CC, Jacoby S, and Andreyeva E
- Subjects
- Wounds, Gunshot, Firearms, Violence
- Published
- 2017
- Full Text
- View/download PDF
48. PATHWAYS OF SPINDLE FORMATION IN DROSOPHILA MITOTIC AND MEIOTIC CELLS.
- Author
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Andreyeva EN, Pechkovsky EV, Pindyurin AV, and Gatti M
- Subjects
- Animals, Drosophila melanogaster, Microtubules genetics, Spindle Apparatus genetics, Meiosis physiology, Microtubules metabolism, Mitosis physiology, Spindle Apparatus metabolism
- Abstract
Spindle assembly relies on three main classes of microtubules (MTs): MTs nucleated by the centrosomes, MTs nucleated near the chromosomes/kinetochores and MTs nucleated from preexisting MTs through the augmin-based pathway. Here, we review the roles of these microtubule generation pathways in Drosophila spindle assembly. The extant results indicate that female meiotic cells, male meiotic cells, larval brain cells and S2 tissue culture cells exploit specific pathway combinations for generating the MTs necessary for spindle formation. Thus, different Drosophila cell types have specific modes of spindle assembly, which might be related to specific functional and developmental requirements.
- Published
- 2016
49. Polytene chromosomes: 70 years of genetic research.
- Author
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Zhimulev IF, Belyaeva ES, Semeshin VF, Koryakov DE, Demakov SA, Demakova OV, Pokholkova GV, and Andreyeva EN
- Subjects
- Animals, DNA Replication genetics, Dosage Compensation, Genetic, Gene Silencing physiology, Genetics, Chromosomes genetics, Chromosomes ultrastructure, Interphase genetics, Transcription, Genetic genetics
- Abstract
Polytene chromosomes were described in 1881 and since 1934 they have served as an outstanding model for a variety of genetic experiments. Using the polytene chromosomes, numerous biological phenomena were discovered. First the polytene chromosomes served as a model of the interphase chromosomes in general. In polytene chromosomes, condensed (bands), decondensed (interbands), genetically active (puffs), and silent (pericentric and intercalary heterochromatin as well as regions subject to position effect variegation) regions were found and their features were described in detail. Analysis of the general organization of replication and transcription at the cytological level has become possible using polytene chromosomes. In studies of sequential puff formation it was found for the first time that the steroid hormone (ecdysone) exerts its action through gene activation, and that the process of gene activation upon ecdysone proceeds as a cascade. Namely on the polytene chromosomes a new phenomenon of cellular stress response (heat shock) was discovered. Subsequently chromatin boundaries (insulators) were discovered to flank the heat shock puffs. Major progress in solving the problems of dosage compensation and position effect variegation phenomena was mainly related to studies on polytene chromosomes. This review summarizes the current status of studies of polytene chromosomes and of various phenomena described using this successful model.
- Published
- 2004
- Full Text
- View/download PDF
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