483 results on '"Andrews, Rebecca"'
Search Results
2. The Role of Digital Technologies in Supporting Quality Improvement in Australian Early Childhood Education and Care Settings
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Hatzigianni, Maria, Stephenson, Tanya, Harrison, Linda J., Waniganayake, Manjula, Li, Philip, Barblett, Lennie, Hadley, Fay, Andrews, Rebecca, Davis, Belinda, and Irvine, Susan
- Abstract
This national study explored the role of digital technologies in early childhood education and care settings and whether they could contribute to quality improvement as reported by educators and assessors of quality in Australia. In this paper, data from Stage 2 of the Quality Improvement Research Project were used, which comprised 60 Quality Improvement Plans from educators linked with 60 Assessment and Rating reports from the assessors who visited early childhood centres as part of the administration of the National Quality Standards by each of Australia's State and Territory jurisdictions. Bronfenbrenner's ecological systems theory (Bronfenbrenner, U. (1995). Developmental ecology through space and time: A future perspective. In P. Moen, G.H. Elder, Jr., & K. Lüscher (Eds.), Examining lives in context: Perspectives on the ecologyof human development (pp. 619-647). American Psychological Association. https://doi.org/10.1037/10176-018; Bronfenbrenner & Ceci, Bronfenbrenner and Ceci, Psychological Review 101:568-586, 1994) was adopted to facilitate a systemic and dynamic view on the use of digital technologies in these 60 ECEC settings. References (e.g. comments/ suggestions/ examples) made by the educators about the implementation of digital technologies were counted and thematically analysed. Results revealed the strong role new technologies (e.g. documentation and management platforms, tablets, apps, etc.) play in the majority of ECEC settings and especially in relation to three of the seven Quality Areas: Educational programme and practice (Quality Area 1); Collaborative partnerships with families and communities (Quality Area 6) and Governance and leadership (Quality Area 7). Future directions for research are suggested and implications for embracing a more holistic, integrated and broad view on the use of digital technologies are discussed.
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- 2023
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3. Educators', Children's and Mothers' Use of Temporal Language in Reminiscing and Future Talk Conversations
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Andrews, Rebecca, Van Bergen, Penny, and Wyver, Shirley
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We investigated how educators, mothers and children used temporal language in reminiscing and future talk conversations. Participants initially included 40 educator-younger child dyads (27-36 months) and 45 educator-older child dyads (48-60 months) from early childhood centres in Sydney, Australia. Educators were asked to nominate and discuss four past and future events with the participating children. To determine how conversations about different events might vary, temporal focus (past/future) and event novelty (novel/familiar) were manipulated. To enable comparisons between educator-child and mother-child use of temporal language 42 mother-child dyads also completed the same tasks. Educators were noted to use timeless present references to add new information about events. With the older children, educators made significantly more future action and future hypothetical references. Educators' use of future hypothetical references was significantly greater than that of mothers. Educators used reminiscing and future talk conversations to extend children's exposure to temporal language.
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- 2023
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4. The Mentoring Role of Professional Experience Coordinators: Beyond a Sink-Or-Swim Discourse
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Hadley, Fay, Hay, Iain, Andrews, Rebecca, Vale, Vanessa, Winslade, Matthew, editor, Loughland, Tony, editor, and Eady, Michelle J., editor
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- 2023
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5. Quality Improvement Research Project
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Australian Children's Education and Care Quality Authority (ACECQA), Macquarie University (Australia), Queensland University of Technology (QUT) (Australia), Edith Cowan University (ECU) (Australia), Harrison, Linda J., Hadley, Fay, Irvine, Sue, Davis, Belinda, Barblett, Lennie, Hatzigianni, Maria, Mulhearn, Gerry, Waniganayake, Manjula, Andrews, Rebecca, and Li, Philip
- Abstract
Australia's National Quality Framework (NQF) guides State/Territory government regulatory authorities to meet national goals for continuous quality improvement. Australian Children's Education and Care Quality Authority (ACECQA) commissioned Macquarie University to lead a national study of long day care (LDC) services that had improved their National Quality Standard (NQS) rating over two sequential NQS assessments. This report presents findings from the three phase, mixed-methods Quality Improvement Research Project, which investigated the characteristics and internal processes of quality improvement in LDC services. While recognising the integrated nature of the NQS, and interrelationship between the seven quality areas, the study concentrated on Quality Area 1 (Educational Program and Practice) and Quality Area 7 (Governance and Leadership). Genuine and sustained quality improvement is the result of collaborative effort, and therefore needs to be seen as a shared responsibility. The findings place emphasis on the need for leadership at all levels of service delivery and early childhood education and care (ECEC) policy. In particular, the important role of the Educational Leader is highlighted. The study also identifies priority areas to support and sustain quality improvement evidenced by improved Assessment and Rating (A&R) outcomes.
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- 2019
6. A school-based cross-sectional study to understand the public health measures needed to improve the emotional and mental wellbeing of young carers aged 12 to 14 years
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Sharpe, Richard A., Russell, Natalie, Andrews, Rebecca, Curry, Whitney, and Williams, Andrew James
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- 2023
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7. Psychological interventions in Acquired Brain Injury (ABI)
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Andrews, Rebecca
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ABI ,Acquired Brain Injury ,stroke ,Traumatic Brain Injury ,TBI ,acceptance and commitment therapy ,ACT ,Values - Abstract
Background: Psychological distress such as depression is common following ABI and is often more debilitating than changes experienced in thinking and physical abilities. Distress can impact negatively on long-term outcomes including social and occupational functioning, quality of life and adjustment to the injury and its consequences. It is suggested that interventions focusing on an individual's values (what is truly important to them) can improve mood and adjustment, and lead to increased meaningful behaviours despite their injury. However, depression can reduce motivation for engaging in valued activities. In individuals without an ABI, imagery has been shown to increase engagement and motivation for planned activities. The current study therefore explored the use of a values-based intervention for individuals with an ABI and symptoms of depression. Mental imagery was optional and added to the intervention for instances where participants experienced reduced motivation to engage in the values-based activities discussed during therapy sessions. Method: The study aimed to recruit six individuals with an ABI who were undergoing inpatient neurorehabilitation at one of two London hospitals. All participants were over the age of 18 and experiencing symptoms of depression, and were not of high risk (i.e., they did not present with suicidal intent or substance misuse). Participants took part in a values-based intervention, which aimed to increase their engagement in activities that were personally meaningful to them. Measures of psychological distress and values-based behaviour were completed as close to daily as possible during the baseline period of two, three or four weeks, the intervention stage (consisting of five to seven sessions) and the two-week follow-up. Throughout the study participants were also assessed using standardised questionnaires of mood, quality of life, adjustment, future thinking, and behaviour. Data was analysed by comparing participant's scores on each measure to their scores at earlier time points. Results: Four individuals completed the intervention, with three completing follow-ups. The following was found: o All individuals demonstrated an increase in values-consistent behaviour when tracking specific values that were identified in early sessions (i.e., they engaged with more things that mattered to them). o Most participants reported engaging in additional values-based behaviours in addition to those discussed with the therapist. o Three out of four participants improved on at least one questionnaire postintervention, with the most improvement made in depression. However, findings were not always maintained at follow-up and were inconsistent across measures (e.g., participants often demonstrated a reduction in depression on standardised questionnaires but not on daily ratings of low mood). o The intervention was feasible and deemed acceptable by all participants. Conclusions: This was the first study to explore the use of a values-based intervention for neurorehabilitation inpatients with an ABI and symptoms of depression. The flexible nature of the research therapy meant that participants physical and thinking abilities could be considered when establishing value-based activities within sessions, encouraging them to engage in meaningful behaviours despite their injury. Most participants reported increased values-consistent behaviours and reduced symptoms of depression over the course of therapy. However, results were inconsistent across participants and measures. Additionally, study limitations including not reaching the desired number of participants, the sole use of self-report and the uncontrollability of the rehabilitation environment during COVID-19, are likely to have impacted on findings.
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- 2021
8. Development of single-molecule DNA hybridisation tools for high-content analysis of protein-DNA interactions and gene expression
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Andrews, Rebecca and Kapanidis, Achillefs
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This thesis presents results in the development of two single-molecule methods which use DNA hybridisation, in vitro and in vivo, to investigate protein-DNA interactions and processes. Single-molecule DNA sequencing methods have made important contributions to genomics, diagnostics and functional analysis of genetic processes. Despite the fact that there are a large variety of single-molecule sequencing methods, there is currently no systematic way to connect the functional properties, with regards to protein interactions, of a single DNA molecule (single-molecule phenotype) with DNA sequence. In this thesis, I describe proof-of-principle experiments for 'Gap-Seq', a short-read single-molecule sequencing method that interrogates DNA sequence through the transient binding of short fluorescent DNA strands to surface-immobilised gapped-DNA substrates. A way to identify a base can be the dwell times of the short DNAs on the immobilised substrates: the correct base shows comparatively long dwells of the short DNAs on the substrates, whereas, non-complementary bases show no binding or comparatively shorter dwells on the substrates. I also show how single base DNA modifications affect protein-DNA interactions and a method for how Gap-Seq can be implemented to evaluate the DNA sequence at the protein binding site. Once developed further, Gap-Seq will fill a significant void in single-molecule DNA/RNA sequencing and will be important for both mechanistic work and screening libraries of nucleic acids against targets of biomedical importance. I have also used DNA hybridisation to demonstrate the proof-of-principle for a new type of fluorescence in situ hybridisation (FISH) assay in live bacterial cells. Specifically, my work introduces 'in vivo single-molecule FISH' (in vivo smFISH), where short doubly labelled single-stranded DNAs are electroporated into cells and subsequently bind transiently or stably to target RNA. I establish that the electroporated probes exhibit site-specific binding and produce bright fluorescence signals that should lead to direct measurements of the kinetics of gene transcription on the chromosome, and advance the understanding of many fundamental processes involving RNA.
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- 2021
9. Protocol for a mixed-methods investigation of quality improvement in early childhood education and care in Australia
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Harrison, Linda J., Andrews, Rebecca, Hadley, Fay, Irvine, Susan, Waniganayake, Manjula, Barblett, Lennie, Davis, Belinda, Hatzigianni, Maria, and Li, Hui
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- 2023
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10. When and Why Do Early Childhood Educators Reminisce with Children about Their Past Experiences?
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Van Bergen, Penny and Andrews, Rebecca
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When children reminisce with adults about their own past experiences, they are offered a rich forum in which to develop cognitive and socioemotional skills, build their sense of self, and form emotional bonds. Little attention has been directed to reminiscing in educational contexts, however. Our aim was to explore when, how often, and why early childhood educators engage young children in reminiscing conversations. Participants included 251 Australian educators with 1-45 years of experience. Educators completed an online survey asking them (i) the number of times per day they engaged children in reminiscing, relative to other types of talk, and (ii) the times and places these reminiscing conversations were most likely to occur. While individual differences were apparent, more than 85% of educators reporting engaging children in reminiscing multiple times per day. Popular times included arrival (67.7%), meals (65.7%) and group/circle time (58.2%). Educators' qualitative explanations suggested several important reasons to engage children in reminiscing, including to bond, establish home-centre connections, build children's socioemotional competence, reflect on 'centre life' and support intentional learning activities. Implications for research and practice are discussed.
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- 2022
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11. Inviting Inquiry on Pedagogical Documentation in Singapore: Perspectives of Parents and Teachers
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Chng, Angela, Waniganayake, Manjula, and Andrews, Rebecca
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Pedagogical documentation within early childhood centres is a key component of pedagogy and teacher accountability. In Singapore, documentation is a requirement specified under legislative policies included in the national Pre-school Accreditation Framework, with parents often perceived as the main audience. This paper reports on a study utilising Rogoff's observation on social cultural activities to focus on the interconnectedness between children, parents and teachers as stakeholders in the early childhood sector. An electronic survey was used to ascertain parents' perspectives on documentation of their child's learning and development. Analysis of this data was shared in five individual teacher interviews to explore responses to the parents' perspectives. Findings of this study affirmed that documentation varied as a process and a product of pedagogy in early childhood centres. Within a climate of assessment and accountability, these findings invite inquiry and offer possibilities for professional learning on improving pedagogical documentation across the sector.
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- 2022
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12. Distinguishing learned categorical perception from selective attention to adimension: Preliminary evidence from a new method
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Andrews, Janet, de Leeuw, Joshua, Andrews, Rebecca, Landolt, Cole, and Griesmer, Chrissy
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categorical perception ,categorization ,learning ,expansion ,compression ,dimensional modulation ,selectiveattention - Abstract
A novel experimental method is motivated and applied in aneffort to test for effects of category learning on perceptualdiscrimination so as to clearly distinguish category boundaryeffects of expansion and compression from changes insensitivity to stimulus dimensions. The method includes acontrol group performing a task that, like category learning,requires attention to one systematically varying stimulusdimension rather than another. Discrimination accuracy istracked over time and measured using a psychophysicalstaircase procedure tailored to individual participants thatdoesn’t rely on memory. Initial results suggest improvementin discrimination accuracy over time, particularly on thedimension relevant to the categorization or control task, butno evidence of category boundary effects or effects ofcategory learning on dimension perception stronger than thoseof the control task. Possible reasons for this and directions forfurther research are briefly discussed .
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- 2019
13. Systematic review on Cryptococcus neoformans/Cryptococcus gattii species complex infections with recommendations for practice in health and care settings
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van der Torre, Mireille H., Andrews, Rebecca A.J., Hooker, Emma L., Rankin, Annette, and Dodd, Susie
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- 2022
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14. A Follow-Up Study of an Early Childhood Mentoring Program: Sustaining Impactful Change for Mentors and Mentees.
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Andrews, Rebecca, Hadley, Fay, and Hay, Iain
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CAREER development ,EARLY childhood teachers ,MENTORING ,LABOR supply ,MENTORS ,EMPLOYERS - Abstract
Government funded mentoring programs are one strategy to address the supply crisis of early childhood teachers (ECTs) in Australia. There is little or no published research on the long-term impacts of these programs. This paper presents the findings of an evaluation survey completed 18 months after the mentoring program finished, covering the perspectives of experienced ECTs (mentors) and beginning ECTs (mentees). The participants (N = 39) reported personal and professional growth over the period of the program. Subsequently, their enriched knowledge, skills and understanding of mentoring impacted their own, other individuals and wider practices within their workplaces. Enablers to participation were a supportive director and the scheduling of the program out of hours. The predominant challenge for ongoing enactment of learnings was time constraints due to daily demands of early childhood workplaces. Recommendations for sustainability of effective mentoring practices are proffered and warrant the attention of governments, employers and the sector. [ABSTRACT FROM AUTHOR]
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- 2024
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15. The Pathophysiology of Myeloma Bone Disease: Bone Remodelling and the Role of Osteoclasts
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Andrews, Rebecca E., Chantry, Andrew D., Ashcroft, A. John, and Zamagni, Elena, editor
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- 2021
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16. Correction to: The Pathophysiology of Myeloma Bone Disease: Bone Remodelling and the Role of Osteoclasts
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Andrews, Rebecca E., Chantry, Andrew D., Ashcroft, A. John, and Zamagni, Elena, editor
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- 2021
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17. Characteristics of Educators' Talk about Decontextualised Events
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Andrews, Rebecca and Van Bergen, Penny
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This study investigated the characteristics of educators' talk about decontextualised events with young children in seven early childhood long day care centres in Sydney, Australia. Educators were partnered with up to six children aged between 27 and 60 months. Across two time points, 85 educator-child dyads discussed past and future events. Educators' use of questions, contextual statements, evaluations and prompts and children's use of questions, open-ended responses, yes-no responses and spontaneous information statements were examined. Educators' evaluative statements were highly correlated and educators' questions were moderately correlated with children's open-ended responses in past event conversations. Educators' evaluative statements were highly correlated with children's open-ended responses in future event conversations and were the only significant predictor for children's talk. Given the important role of educators in scaffolding children's thinking and communication skills, the recommended strategies for educators' talk in decontextualised conversations include: sharing the conversational load, making frequent contextual statements and following the child's lead/interests.
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- 2020
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18. Use of Mental State Language during Educator-Child and Mother-Child Conversations about the Past and Future
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Andrews, Rebecca, Van Bergen, Penny, and Wyver, Shirley
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Research findings: No research to date has compared mental state language (MSL) in conversations between children and different adult talk partners, such as mothers and educators. The aim of this study was to investigate the use of MSL (verbalization of mental states such as remembering, knowing and thinking) by children, educators, and mothers during conversations about the past and future. Eighty-five educator-child dyads from seven childcare centers in Sydney, Australia participated in eight conversations that varied by temporal (past/future) and novelty (novel/familiar) focus. Ten educators talked with 40 younger children (27-36 months), and 11 talked with 45 older children (48-60 months). A subsample of 42 mother-child dyads completed the same tasks: 20 with the younger children (27-36 months) and 22 with the older children (48-60 months). Educators used significantly more MSL than mothers. Compared to diploma-qualified educators, degree trained educators were especially likely to use more MSL. Educators' MSL was significantly associated with children's MSL for future talk conversations only. Practice or Policy: Educators' and mothers' MSL may influence children in different ways. Pre-service teacher training appears to facilitate educators' own use of MSL. More research is needed to determine why children use more MSL with their mothers than with their educators. Practice or Policy
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- 2020
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19. Amino Functionality Enables Aqueous Synthesis of Carboxylic Acid-Based MOFs at Room Temperature by Biomimetic Crystallization
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Wang, Xiangyu, primary, Singh, Samarth Pratap, additional, Zhang, Tongtong, additional, Andrews, Rebecca, additional, Lizio, Maria Giovanna, additional, Whitehead, George F. S., additional, and Riddell, Imogen A., additional
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- 2024
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20. RASP: Optimal Single Puncta Detection in Complex Cellular Backgrounds
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Fu, Bin, primary, Brock, Emma E., additional, Andrews, Rebecca, additional, Breiter, Jonathan C., additional, Tian, Ru, additional, Toomey, Christina E., additional, Lachica, Joanne, additional, Lashley, Tammaryn, additional, Ryten, Mina, additional, Wood, Nicholas W., additional, Vendruscolo, Michele, additional, Gandhi, Sonia, additional, Weiss, Lucien E., additional, Beckwith, Joseph S., additional, and Lee, Steven F., additional
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- 2024
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21. The quest for continuous quality improvement in Australian long day care services: Getting the most out of the assessment and rating process
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Irvine, Susan L., Barblett, Lennie, Waniganayake, Manjula, Hadley, Fay, Andrews, Rebecca, Hatzigianni, Maria, Li, Hui, Lavina, Leanne, Harrison, Linda J., Davis, Belinda, Irvine, Susan L., Barblett, Lennie, Waniganayake, Manjula, Hadley, Fay, Andrews, Rebecca, Hatzigianni, Maria, Li, Hui, Lavina, Leanne, Harrison, Linda J., and Davis, Belinda
- Abstract
The National Quality Framework (NQF) was intended to drive continuous improvement in education and care services in Australia. Ten years into implementation, the effectiveness of the NQF is demonstrated by steady improvements in quality as measured against the National Quality Standard (NQS). The process of assessing and rating services is a key element in the NQF, drawing together regulatory compliance and quality assurance. This paper draws on findings from a national Quality Improvement Research Project investigating the characteristics, processes, challenges and enablers of quality improvement in long day care services, concentrating on Quality Area 1 Educational program and practice and Quality Area 7 Governance and leadership. This was a mixed-method study focusing on long day care services that had improved their rating from Working toward NQS to Meeting NQS or to Exceeding NQS. The study comprised three phases, and in this paper, we draw on Phase 3 to understand the contribution of the NQS Assessment and Rating (A&R) process to continuous quality improvement from the standpoint of providers and professionals delivering these services. Phase 3 involved qualitative case studies of 15 long day care services to investigate factors that enabled and challenged quality improvement. Data was collected during two-day site visits, using professional conversations and field notes to elicit the views and experiences of service providers, leaders and educators. In this paper, we look at how the A&R process is experienced by those involved in service provision, with a focus on the factors that enabled and challenged quality improvement. Recognizing the interchangeability of enablers and challenges, three broad themes emerged: (i) curriculum knowledge, pedagogical skills and agency; (ii) collaborative leadership and teamwork; and (iii) meaningful engagement in the A&R process. The study found that meaningful engagement in the A&R process informed priorities for ongoing lea
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- 2024
22. Evidence for peri-lacunar remodeling and altered osteocyte lacuno-canalicular network in mouse models of myeloma-induced bone disease.
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Evans, Holly, Andrews, Rebecca, Abedi, Fatma Ali, Sprules, Alexandria, Trend, Jacob, Lovric, Goran, Green, Alanna, Chantry, Andrew, Clarkin, Claire, Brown, Janet, and Lawson, Michelle
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SCLEROSTIN ,BONE cells ,STAINS & staining (Microscopy) ,MULTIPLE myeloma ,X-ray computed microtomography - Abstract
Myeloma bone disease (MBD) affects ~90% of multiple myeloma patients, but current treatment options are suboptimal. Therefore, to successfully develop new therapies or optimize current ones, we must improve our fundamental knowledge of how myeloma affects bone microstructure and function. Here, we have investigated the osteocyte lacuno-canalicular network (LCN) in MBD, as bone porosity affects bone quality and resilience. We used the syngeneic 5TGM1-C57BL-Kalwrij and the xenograft U266-NSG models at end stage and compared them to healthy controls (naïve). Micro-computed tomography (μCT) and histomorphometry indicated the 5TGM1 and U266 models developed mild and extensive MBD, respectively, with the U266 model producing large osteolytic lesions. High-resolution synchrotron micro-CT (SR-μCT) revealed significant osteocyte lacunae changes in U266 bones but not 5TGM1, with a reduction in lacunae number and sphericity, and an increase in lacunae volume compared with naïve. Canalicular length, visualized using histological Ploton silver staining, appeared significantly shorter in 5TGM1 and U266 bones compared with naïve. Canalicular area as a proportion of the bone was also decreased by 24.2% in the U266 model. We observed significant upregulation of genes implicated in peri-lacunar remodeling (PLR), but immunohistochemistry confirmed that the osteocyte-specific protein sclerostin, a known driver of PLR, was unchanged between MBD and naïve bones. In summary, we have demonstrated evidence of PLR and altered organization of the osteocyte LCN in MBD mouse models. The next step would be to further understand the drivers and implications of PLR in MBD, and whether treatments to manipulate PLR and the LCN may improve patient outcomes. Lay Summary: Multiple myeloma is a blood cancer that causes bone damage in ~90% of patients. Currently, treatment options for myeloma bone disease (MBD) are suboptimal, leaving patients with chronic pain and increased fracture risk. Therefore, it is important that we improve our fundamental knowledge of how myeloma causes bone damage. With the development of more powerful imaging technologies, this allows us to visualize bone at the submicron level. Here, we assessed bones from two murine models of MBD (termed 5TGM1 and U266) and compared them to bones from healthy control mice (naïve). Using high-resolution imaging (SR-μCT), we found structural changes in the pores where the most abundant bone cells (osteocytes) reside, and that the orientation of their signaling network (lacuno-canalicular network, LCN) is altered in MBD compared with healthy bones. We also found differences in gene expression of key molecules in osteocytes from bones with MBD compared with healthy bones and identified a potential mechanism leading to these changes. The next step would be to use this knowledge to determine how myeloma treatments can affect the osteocyte LCN, as this may allow informed treatment decisions to be made, potentially reducing fracture risk and improving outcomes for patients with MBD. Graphical Abstract [ABSTRACT FROM AUTHOR]
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- 2024
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23. Large-scale visualisation of α-synuclein oligomers in Parkinson's disease brain tissue
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Andrews, Rebecca, primary, Fu, Bin, additional, Toomey, Christina E., additional, Breiter, Jonathan C., additional, Lachica, Joanne, additional, Tian, Ru, additional, Beckwith, Joseph S., additional, Needham, Lisa-Maria, additional, Chant, Gregory J., additional, Loiseau, Camille, additional, Deconfin, Angèle, additional, Baspin, Kenza, additional, Magill, Peter J., additional, Jaunmuktane, Zane, additional, Freeman, Oliver J., additional, Taylor, Benjamin J.M., additional, Hardy, John, additional, Lashley, Tammaryn, additional, Ryten, Mina, additional, Vendruscolo, Michele, additional, Wood, Nicholas W., additional, Weiss, Lucien E., additional, Gandhi, Sonia, additional, and Lee, Steven F., additional
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- 2024
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24. The quest for continuous quality improvement in Australian long day care services: getting the most out of the Assessment and Rating process
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Irvine, Susan Lee, primary, Barblett, Lennie, additional, Waniganayake, Manjula, additional, Hadley, Fay, additional, Andrews, Rebecca, additional, Hatzigianni, Maria, additional, Li, Hui, additional, Lavina, Leanne, additional, Harrison, Linda J., additional, and Davis, Belinda, additional
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- 2024
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25. Single-Molecule Antibody Slides For Fluorescence Microscopy v1
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Andrews, Rebecca, primary
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- 2024
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26. The hyperfine Paschen-Back Faraday effect
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Zentile, Mark A, Andrews, Rebecca, Weller, Lee, Knappe, Svenja, Adams, Charles S, and Hughes, Ifan G
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Physics - Atomic Physics ,Physics - Optics ,Quantum Physics - Abstract
We investigate experimentally and theoretically the Faraday effect in an atomic medium in the hyperfine Paschen-Back regime, where the Zeeman interaction is larger than the hyperfine splitting. We use a small permanent magnet and a micro-fabricated vapour cell, giving magnetic fields of the order of a Tesla. We show that for low absorption and small rotation angles, the refractive index is well approximated by the Faraday rotation signal, giving a simple way to measure the atomic refractive index. Fitting to the atomic spectra, we achieve magnetic field sensitivity at the $10^{-4}$ level. Finally we note that the Faraday signal shows zero crossings which can be used as temperature insensitive error signals for laser frequency stabilisation at large detuning. The theoretical sensitivity for $^{87}$Rb is found to be $\sim 40$ kHz/$^\circ$C., Comment: 8 pages, 4 figures
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- 2014
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27. Raising the Quality of Praxis in Online Mentoring
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Kelly, Nick, Kickbusch, Steven, Hadley, Fay, Andrews, Rebecca, Wade-Leeuwen, Bronwen, O’Brien, Mia, Kriewaldt, Jeana, editor, Ambrosetti, Angelina, editor, Rorrison, Doreen, editor, and Capeness, Ros, editor
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- 2018
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28. Reconsidering the Communicative Space: Learning to Be
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O’Brien, Mia, Wade-Leeuwen, Bronwen, Hadley, Fay, Andrews, Rebecca, Kelly, Nick, Kickbusch, Steven, Kriewaldt, Jeana, editor, Ambrosetti, Angelina, editor, Rorrison, Doreen, editor, and Capeness, Ros, editor
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- 2018
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29. Daily Passive Muscle Stretching Improves Flow-Mediated Dilation of Popliteal Artery and 6-minute Walk Test in Elderly Patients with Stable Symptomatic Peripheral Artery Disease
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Hotta, Kazuki, Batchelor, Wayne B., Graven, James, Dahya, Vishal, Noel, Thomas E., Ghai, Akash, Katopodis, John N., Dixon, William C., Andrews, Rebecca, Pragle, Aimee, Chheda, Jegghna, Liberatore, Lia, Behnke, Brad J., and Muller-Delp, Judy
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- 2019
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30. Relational Pedagogies
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Van Bergen, Penny and Andrews, Rebecca
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- 2022
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31. Reminiscing and future talk conversations between young children, their early childhood educators and mothers
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Andrews, Rebecca, Van Bergen, Penny, and Wyver, Shirley
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- 2019
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32. Placing a child with learning disabilities into out-of-home care : parents' and caregivers' decision making processes and 'breaking point' : a grounded theory exploration
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Andrews, Rebecca
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150 ,children ,learning disabilities ,care ,grounded theory - Abstract
Research suggests that parents of children with learning disabilities are particularly vulnerable to stress and that parental distress impacts negatively on family functioning, parenting roles and relationships, behaviours, socialisation and the psychological well-being of both parent and child; as a consequence many parents reach ‘breaking point’ and will choose to place their child in out-of-home care. However, the research literature outlining this process is limited. The purpose of this research was twofold: to explore the process leading to ‘breaking point’ in parents and caregivers of children with learning disabilities and how this impacted on the decision making process leading to out-of-home care, and secondly, to formulate a grounded theory of this process and its consequences. The study used a social constructionist grounded theory methodology. Fourteen participants were interviewed and three participants completed a qualitative survey. The sample included two birth fathers, twelve birth mothers, one adoptive mother, one sibling and one guardian. The level of their child’s learning disability varied from mild to severe. In all cases, the child had additional diagnoses, such as autism, fragile-X syndrome and Down’s syndrome. A grounded theory was constructed from the data outlining the basic psychosocial process which led to ‘breaking point’ and the decision to place the child in out-of-home care. Parents developing awareness of their child’s disability combined with social prejudice, contributed to the development of a negative parental identity. To defend against this, parents created a compensatory good parent identity and in doing so convinced themselves that they could cope with the 24/7 child. This increased stress, caused relationship breakdowns, financial difficulties and mental health problems. Parents faced additional stressors when screaming to be heard by professionals as they sought guidance, diagnosis and support. Eventually breaking point was experienced as they became overwhelmed. This initiated the decision making about out-of-home care. Once the move occurred, a process of adjusting and managing the loss of role was entered, linking to evaluation and constant monitoring of care. In this sense parental responsibility was never relinquished and parental roles were redefined. The findings outline a lack of support, information and guidance for parents and families based on their experiences of prejudice and dismissal of concerns by society, professionals and on occasion family and friends. Suggestions for future research and research limitations are explored. The implications for practice and more generally for counselling psychology are also considered.
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- 2014
33. Quality Indicators for Major Depressive Disorder in Adults: A Review of Performance Measures by the American College of Physicians.
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Qaseem, Amir, Andrews, Rebecca A., Campos, Karen, Goldzweig, Caroline L., MacDonald, Scott, McLean, Robert M., Powell, Rhea E., and Fitterman, Nick
- Subjects
- *
MENTAL depression , *SUICIDE risk assessment , *PHYSICIANS , *ADULTS , *HOSPITAL accreditation , *AFFECTIVE disorders - Abstract
This position paper from the American College of Physicians (ACP) presents a review of current performance measures for major depressive disorder (MDD) to inform physicians, payers, and policymakers about their quality and appropriateness for use in various measurement programs. The paper also highlights challenges related to developing performance measures that address MDD management. Major depressive disorder (MDD) is a severe mood disorder that affects at least 8.4% of the adult population in the United States. Characteristics of MDD include persistent sadness, diminished interest in daily activities, and a state of hopelessness. The illness may progress quickly and have devastating consequences if left untreated. Eight performance measures are available to evaluate screening, diagnosis, and successful management of MDD. However, many performance measures do not meet the criteria for validity, reliability, evidence, and meaningfulness. The American College of Physicians (ACP) embraces performance measurement as a means to externally validate the quality of care of practices, medical groups, and health plans and to drive reimbursement processes. However, a plethora of performance measures that provide low or no value to patient care have inundated physicians, practices, and systems and burdened them with collecting and reporting of data. The ACP's Performance Measurement Committee (PMC) reviews performance measures using a validated process to inform regulatory and accreditation bodies in an effort to recognize high-quality performance measures, address gaps and areas for improvement in performance measures, and help reduce reporting burden. Out of 8 performance measures, the PMC found only 1 measure (suicide risk assessment) that was valid at all levels of attribution. This paper presents a review of MDD performance measures and highlights opportunities to improve performance measures addressing MDD management. [ABSTRACT FROM AUTHOR]
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- 2024
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34. Evolving use of recreational drugs in UK—nitazenes and xylazine
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Nahar, Limon Khatun, primary, Andrews, Rebecca, additional, and Paterson, Sue, additional
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- 2023
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35. Role of The Osteoclast in Cancer
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Green, Alanna Claire, primary, Andrews, Rebecca Elizabeth, additional, and Lawson, Michelle Anne, additional
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- 2020
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36. Analysis of cannabinoids in post-mortem blood and hair : its value in post-mortem toxicology
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Andrews, Rebecca, Paterson, Sue, and Murphy, Kevin
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610 - Abstract
The work presented in this thesis describes the development of methods for the analysis of cannabinoids in post-mortem blood samples and hair specimens from cannabis users. It investigates the value of measuring post-mortem blood cannabinoid concentrations and potential value of analysis for cannabinoids in hair for post-mortem toxicology. The development and validation of a method for analysis of cannabinioids in post-mortem blood is described. The method involved liquid-liquid extraction (LLE) of the cannabinoids ∆9-tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN) and metabolites 11-hydroxy-∆9-tetrahydrocannabinol (11-OH-THC) and 11-nor-∆9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) from post-mortem blood followed by analysis by two dimensional gas chromatography-mass spectrometry (2D GC-MS). The developed method was applied to post-mortem blood samples submitted by Her Majesty’s (HM) Coroners from fatal road traffic collisions (RTCs) and other routine case types (control group). The prevalence of cannabinoids in the RTC and control group was similar (21% of the RTC group and 26% of the control group were positive for at least one cannabinoid), however, 90% of the cannabinoid positive RTCs had detectable THC (the psychoactive component of cannabis), compared to 60% of the cannabinoid positive control cases. It was demonstrated that it is feasible to indicate possible impairment due to cannabis use in fatal RTCs when the concentration of THC detected is higher than those usually observed in other routine HM Coroners’ cases. A method was developed for analysis of THC, CBD, CBN and THC-COOH from hair. The method involved LLE combined with solid phase extraction (SPE) from hair followed by analysis by 2D GC-MS and standard GC-MS. The developed method was applied to 31 authentic hair specimens from regular cannabis users. The method was suitable for detecting exposure (by detection of THC, CBD and CBN) in weekly users but may only prove ingestion in daily users (by detection of THC-COOH).
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- 2013
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37. Gastrostomies Preserve But Do Not Increase Quality of Life for Patients and Caregivers
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Kurien, Matthew, Andrews, Rebecca E., Tattersall, Rachel, McAlindon, Mark E., Wong, Emma F., Johnston, Alex J., Hoeroldt, Barbara, Dear, Keith L., and Sanders, David S.
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- 2017
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38. High-throughput super-resolution analysis of influenza virus pleomorphism reveals insights into viral spatial organization
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McMahon, Andrew, primary, Andrews, Rebecca, additional, Groves, Danielle, additional, Ghani, Sohail V., additional, Cordes, Thorben, additional, Kapanidis, Achillefs N., additional, and Robb, Nicole C., additional
- Published
- 2023
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39. Mapping the leap: differences in quality improvement in relation to assessment rating outcomes
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Davis, Belinda, primary, Dunn, Rosemary, additional, Harrison, Linda J., additional, Waniganayake, Manjula, additional, Hadley, Fay, additional, Andrews, Rebecca, additional, Li, Hui, additional, Irvine, Susan, additional, Barblett, Lennie, additional, and Hatzigianni, Maria, additional
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- 2023
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40. Metastatic Infiltration of Nervous Tissue and Periosteal Nerve Sprouting in Multiple Myeloma-Induced Bone Pain in Mice and Human
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Diaz-delCastillo, Marta, primary, Palasca, Oana, additional, Nemler, Tim T., additional, Thygesen, Didde M., additional, Chávez-Saldaña, Norma A., additional, Vázquez-Mora, Juan A., additional, Ponce Gomez, Lizeth Y., additional, Jensen, Lars Juhl, additional, Evans, Holly, additional, Andrews, Rebecca E., additional, Mandal, Aritri, additional, Neves, David, additional, Mehlen, Patrick, additional, Caruso, James P., additional, Dougherty, Patrick M., additional, Price, Theodore J., additional, Chantry, Andrew, additional, Lawson, Michelle A., additional, Andersen, Thomas L., additional, Jimenez-Andrade, Juan M., additional, and Heegaard, Anne-Marie, additional
- Published
- 2023
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41. Mapping the leap: Differences in quality improvement in relation to assessment rating outcomes
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Davis, Belinda, Dunn, Rosemary, Harrison, Linda J., Waniganayake, Manjula, Hadley, Fay, Andrews, Rebecca, Li, Hui, Irvine, Susan, Barblett, Lennie, Hatzigianni, Maria, Davis, Belinda, Dunn, Rosemary, Harrison, Linda J., Waniganayake, Manjula, Hadley, Fay, Andrews, Rebecca, Li, Hui, Irvine, Susan, Barblett, Lennie, and Hatzigianni, Maria
- Abstract
Introduction: Australia’s National Quality Standard (NQS) outlines the criteria to assess the quality of early childhood services. A four-point rating scale: (i) Exceeding NQS; (ii) Meeting NQS; (iii) Working Toward NQS; and (iv) Significant Improvement Required is applied to services following a regular assessment and rating process. Settings rated as Working Toward are reassessed within 12 months. Most settings achieved a one-step improvement in this Time 2 reassessment, moving to a Meeting rating but some settings made a two-step improvement, moving to an Exceeding rating. The QIP is a key document used by authorities to assess the quality of a service. Methods: A grounded theory, data driven approach was taken to deepen understanding of quality rating improvements in long day care services in Australia of quality rating improvements by early childhood education and care [ECEC] services in Australia. This study, part of the second phase of a three phase study involved a document analysis of the Time 2 Quality Improvement Plans (QIPs) of a representative sample of Long Day Care (LDC) services (n = 60) from all Australian states and territories to determine what factors may have contributed to these different levels of improvement, with a focus on Quality Area 1 (QA1) (Educational programs and practices) and Quality Area 7 (QA7) (Governance and leadership). The study utilized the semantic analysis tool Leximancer 4.5. Leximancer 4.5 statistically analyses the semantic relationships between concepts in documents by measuring word proximity and correlation. The software creates visual maps of concepts and their connections to each other in texts. Concepts located near one another on the map are more likely to be contextually related. This tool is particularly useful when there are multiple, complex documents to analyze, reducing the potential biases that can arise from documents that use language with which these researchers are very familiar with. Results: The analy
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- 2023
42. Structures and systems influencing quality improvement in Australian early childhood education and care centres
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Harrison, Linda J., Waniganayake, Manjula, Brown, Jude, Andrews, Rebecca, Li, Hui, Hadley, Fay, Irvine, Susan, Barblett, Lennie, Davis, Belinda, Hatzigianni, Maria, Harrison, Linda J., Waniganayake, Manjula, Brown, Jude, Andrews, Rebecca, Li, Hui, Hadley, Fay, Irvine, Susan, Barblett, Lennie, Davis, Belinda, and Hatzigianni, Maria
- Abstract
This study assessed the impact of structural characteristics on quality rating and improvement systems (QRIS) outcomes in an Australian national study. Data from the Australian Children's Education and Care Quality Authority (ACECQA) repository of National Quality Standard (NQS) ratings were used to identify long day care services that had improved from Working Towards NQS to Meeting or Exceeding NQS or had no change over two assessments. QRIS outcomes were examined for state/territory jurisdiction, urban–rural location, community socio-economic status, type and size of provider organisation, centre size and stability of centre owner/provider using multinomial logistic regression analyses. Controlling for jurisdiction, results showed that improvement to Meeting NQS was more likely for not-for-profit versus for-profit providers and for large multi-site provider organisations versus small, stand-alone providers. Improvement to Exceeding NQS was also associated with not-for-profit and larger provider organisations, as well as larger versus smaller centres, and centres that had stable ownership.
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- 2023
43. Metastatic Infiltration of Nervous Tissue and Periosteal Nerve Sprouting in Multiple Myeloma-Induced Bone Pain in Mice and Human
- Author
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Diaz-delCastillo, Marta, Palasca, Oana, Nemler, Tim T., Thygesen, Didde M, Chávez-Saldaña, Norma A, Vázquez-Mora, Juan A, Ponce Gomez, Lizeth Y, Jensen, Lars Juhl, Evans, Holly, Andrews, Rebecca E, Mandal, Aritri, Neves, David, Mehlen, Patrick, Caruso, James P, Dougherty, Patrick M, Price, Theodore J, Chantry, Andrew, Lawson, Michelle A, Andersen, Thomas L, Jimenez-Andrade, Juan M, Heegaard, Anne-Marie, Diaz-delCastillo, Marta, Palasca, Oana, Nemler, Tim T., Thygesen, Didde M, Chávez-Saldaña, Norma A, Vázquez-Mora, Juan A, Ponce Gomez, Lizeth Y, Jensen, Lars Juhl, Evans, Holly, Andrews, Rebecca E, Mandal, Aritri, Neves, David, Mehlen, Patrick, Caruso, James P, Dougherty, Patrick M, Price, Theodore J, Chantry, Andrew, Lawson, Michelle A, Andersen, Thomas L, Jimenez-Andrade, Juan M, and Heegaard, Anne-Marie
- Abstract
Multiple myeloma (MM) is a neoplasia of B plasma cells that often induces bone pain. However, the mechanisms underlying myeloma-induced bone pain (MIBP) are mostly unknown. Using a syngeneic MM mouse model, we show that periosteal nerve sprouting of calcitonin gene-related peptide (CGRP+) and growth associated protein 43 (GAP43+) fibers occurs concurrent to the onset of nociception and its blockade provides transient pain relief. MM patient samples also showed increased periosteal innervation. Mechanistically, we investigated MM induced gene expression changes in the dorsal root ganglia (DRG) innervating the MM-bearing bone of male mice and found alterations in pathways associated with cell cycle, immune response and neuronal signaling. The MM transcriptional signature was consistent with metastatic MM infiltration to the DRG, a never-before described feature of the disease that we further demonstrated histologically. In the DRG, MM cells caused loss of vascularization and neuronal injury, which may contribute to late-stage MIBP. Interestingly, the transcriptional signature of a MM patient was consistent with MM cell infiltration to the DRG. Overall, our results suggest that MM induces a plethora of peripheral nervous system alterations that may contribute to the failure of current analgesics and suggest neuroprotective drugs as appropriate strategies to treat early onset MIBP.SIGNIFICANCE STATEMENT Multiple myeloma (MM) is a painful bone marrow cancer that significantly impairs the quality of life of the patients. Analgesic therapies for myeloma-induced bone pain (MIBP) are limited and often ineffective, and the mechanisms of MIBP remain unknown. In this manuscript, we describe cancer-induced periosteal nerve sprouting in a mouse model of MIBP, where we also encounter metastasis to the dorsal root ganglia (DRG), a never-before described feature of the disease. Concomitant to myeloma infiltration, the lumbar DRGs presented blood vessel damage and transcriptional
- Published
- 2023
44. 'Because Uni Is Totally Different than What You Do at TAFE': Protective Strategies and Provisions for Diploma Students Traversing Their First Professional Experience Placement at University
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Hadley, Fay and Andrews, Rebecca
- Abstract
Students who enrol in a Bachelor of Education (Early Childhood Education) at the Institute of Early Childhood, Macquarie University, with a Diploma in Children's Services attained from a Technical and Further Education (TAFE) institution or a Registered Training Organisation (RTO) often experience challenges in their first professional experience unit. Utilising a phenomenological approach to understand the students' previous knowledge and experiences as they navigated through their first professional experience unit, this qualitative study identified factors including institutional structures and course content as challenging to the diploma student. To ensure diploma students can successfully transition to and participate in their first professional experience unit at university, all stakeholders including the university, the academics teaching the students, and the students themselves need to commit to a multilevel support programme. Key findings from this study support the previous research on this student cohort.
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- 2015
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45. What Is the Antibody Response and Role in Conferring Natural Immunity After SARS-CoV-2 Infection? Rapid, Living Practice Points From the American College of Physicians (Version 2)
- Author
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Qaseem, Amir, Yost, Jennifer, Etxeandia-Ikobaltzeta, Itziar, Forciea, Mary Ann, Abraham, George M., Miller, Matthew C., Obley, Adam J., Humphrey, Linda L., Akl, Elie A., Andrews, Rebecca, Dunn, Andrew, Haeme, Ray, Kansagara, Devan L., and P. Tschanz, CDR Mark
- Subjects
medicine.medical_specialty ,COVID-19 Vaccines ,viruses ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,MEDLINE ,Appropriate use ,Antibodies, Viral ,COVID-19 Testing ,Physicians ,Health care ,Agency (sociology) ,medicine ,Internal Medicine ,Humans ,skin and connective tissue diseases ,Intensive care medicine ,business.industry ,SARS-CoV-2 ,Public health ,fungi ,Foundation (evidence) ,COVID-19 ,General Medicine ,biochemical phenomena, metabolism, and nutrition ,Immunity, Innate ,respiratory tract diseases ,body regions ,Antibody response ,Reinfection ,Antibody Formation ,business ,Clinical Guidelines - Abstract
Antibody tests for SARS-CoV-2, the virus that causes COVID-19, are widely available. These practice points help clinicians, patients, and public health professionals understand how to use and interpret these results on the basis of the available evidence. The practice points will be updated as more evidence becomes available., Description: The widespread availability of SARS-CoV-2 antibody tests raises important questions for clinicians, patients, and public health professionals related to the appropriate use and interpretation of these tests. The Scientific Medical Policy Committee (SMPC) of the American College of Physicians developed these rapid, living practice points to summarize the current and best available evidence on the antibody response to SARS-CoV-2 infection, antibody durability after initial infection with SARS-CoV-2, and antibody protection against reinfection with SARS-CoV-2. Methods: The SMPC developed these rapid, living practice points based on a rapid and living systematic evidence review done by the Portland VA Research Foundation and funded by the Agency for Healthcare Research and Quality. Ongoing literature surveillance is planned through December 2021. When new studies are identified and a full update of the evidence review is published, the SMPC will assess the new evidence and any effect on the practice points. Practice Points: Practice Point 1: Do not use SARS-CoV-2 antibody tests for the diagnosis of SARS-CoV-2 infection. Practice Point 2: Antibody tests can be useful for the purpose of estimating community prevalence of SARS-CoV-2 infection. Practice Point 3: Current evidence is uncertain to predict presence, level, or durability of natural immunity conferred by SARS-CoV-2 antibodies against reinfection (after SARS-CoV-2 infection).
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- 2022
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46. Relatively (im)permanent: The ever-changing scope of the Clean Water Act.
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Hagerty, Shawn, Andrews, Rebecca, and Johnson, Samuel
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- *
WETLANDS , *VERNAL pools , *TERRITORIAL waters ,CLEAN Water Act of 1972 (U.S.) - Abstract
The article discusses the Supreme Court case Sackett v. EPA, which addressed the jurisdictional scope of the Clean Water Act (CWA) and the definition of "waters of the United States" (WOTUS). The Court's decision in Sackett attempted to provide a clear definition of WOTUS, but ongoing litigation, proposed legislation, and ambiguities in the decision have led to continued debate on the true meaning of WOTUS. Following the decision, the Environmental Protection Agency (EPA) and the Army Corps of Engineers (Corps) revised their regulations to align with the Court's narrower definition. However, the revised regulations are only operative in 23 states and the District of Columbia, creating a patchwork regulatory scheme across the country. Additionally, a bill has been introduced in Congress to expand the scope of the CWA, but it is expected to face opposition and likely fail. Overall, the Sackett decision has provided some clarity but has also raised new questions and sparked further litigation. [Extracted from the article]
- Published
- 2024
47. Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 2).
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Qaseem, Amir, Yost, Jennifer, Abraham, George M., Andrews, Rebecca, Jokela, Janet A., Miller, Matthew C., Humphrey, Linda L., Obley, Adam J., Akl, Elie A., Dunn, Andrew, Forciea, Mary Ann, Haeme, Ray, Kansagara, Devan L., Lee, Rachael, Mackey, Katherine, Marcucci, Maura, Saini, Sameer D., Tschanz, CDR Mark P., Wilt, Timothy J., and Carroll, Kate
- Subjects
COVID-19 treatment ,SARS-CoV-2 Omicron variant ,PHYSICIANS ,MEDICAL sciences ,HEALTH policy - Abstract
The Population Health and Medical Science Committee of the American College of Physicians (ACP) updates the living, rapid practice points on the treatment of adults with COVID-19 in an outpatient setting. Practice points are based on a living, rapid review done by the ACP Center for Evidence Reviews at Cochrane Austria at the University for Continuing Education Krems. Description: Evidence for the use of outpatient treatments in adults with confirmed COVID-19 continues to evolve with new data. This is version 2 of the American College of Physicians (ACP) living, rapid practice points focusing on 22 outpatient treatments for COVID-19, specifically addressing the dominant SARS-CoV-2 Omicron variant. Methods: The Population Health and Medical Science Committee (formerly the Scientific Medical Policy Committee) developed this version of the living, rapid practice points on the basis of a living, rapid review done by the ACP Center for Evidence Reviews at Cochrane Austria at the University for Continuing Education Krems (Danube University Krems). This topic will be maintained as living and rapid by continually monitoring and assessing the impact of new evidence. Practice Point 1: Consider molnupiravir to treat symptomatic patients with confirmed mild to moderate COVID-19 in the outpatient setting who are within 5 days of the onset of symptoms and at a high risk for progressing to severe disease. Practice Point 2: Consider nirmatrelvir–ritonavir combination therapy to treat symptomatic patients with confirmed mild to moderate COVID-19 in the outpatient setting who are within 5 days of the onset of symptoms and at a high risk for progressing to severe disease. Practice Point 3: Do not use ivermectin to treat patients with confirmed mild to moderate COVID-19 in the outpatient setting. Practice Point 4: Do not use sotrovimab to treat patients with confirmed mild to moderate COVID-19 in the outpatient setting. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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48. Quality Indicators for Osteoporosis in Adults: A Review of Performance Measures by the American College of Physicians.
- Author
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Qaseem, Amir, Mount, Cristin A., Campos, Karen, McLean, Robert M., Tierney, Samantha, Cross Jr., J. Thomas, Fitterman, Nick, Cross, J. Thomas, Andrews, Rebecca A., Basch, Peter, Goldzweig, Caroline L., MacDonald, Scott T., MacLean, Catherine H., Mathew, Suja M., Powell, Rhea E., and Saini, Sameer D.
- Subjects
BONE fractures ,HIP fractures ,PHYSICIANS ,OSTEOPOROSIS ,BONE density ,ADULTS ,VERTEBRAL fractures - Abstract
Several performance measures have been developed to assess and improve osteoporosis screening, diagnosis, and treatment. These performance measures vary in quality but are often used in accountability, public reporting, and/or payment programs. This article evaluates 6 osteoporosis performance measures relevant to internal medicine physicians to inform physicians, payers, and policy makers in their selection and interpretation of performance measures for this condition. Primary osteoporosis is characterized by decreasing bone mass and density and reduced bone strength that leads to a higher risk for fracture, especially hip and spine fractures. The prevalence of osteoporosis in the United States is estimated at 12.6% for adults older than 50 years. Although it is most frequently diagnosed in White and Asian females, it still affects males and females of all ethnicities. Osteoporosis is considered a major health issue, which has prompted the development and use of several performance measures to assess and improve the effectiveness of screening, diagnosis, and treatment. These performance measures are often used in accountability, public reporting, and/or payment programs. However, the reliability, validity, evidence, attribution, and meaningfulness of performance measures have been questioned. The purpose of this paper is to present a review of current performance measures on osteoporosis and inform physicians, payers, and policymakers in their selection of performance measures for this condition. The Performance Measurement Committee identified 6 osteoporosis performance measures relevant to internal medicine physicians, only 1 of which was found valid at all levels of attribution. This paper also proposes a performance measure concept to address a performance gap for the initial approach to therapy for patients with a new diagnosis of osteoporosis based on the current American College of Physicians guideline. [ABSTRACT FROM AUTHOR]
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- 2023
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49. Annals On Call - Outpatient Treatment of COVID-19
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Centor, Robert M., primary and Andrews, Rebecca, additional
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- 2023
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- View/download PDF
50. Single-molecule Immunofluorescence Tissue Staining Protocol for Oligomer Imaging v2
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Andrews, Rebecca, primary and Lachica, Joanne, additional
- Published
- 2023
- Full Text
- View/download PDF
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