Hypertension (HTN), or high blood pressure (BP), is the leading cause of cardiovascular disease-related death and disability worldwide (1). Deemed a global epidemic by the World Health Organization (2-6), HTN is the most commonly diagnosed chronic condition in primary care (7-9). BP control is inadequate world-wide, with more than half of patients not treated to within clinical target ranges (10). Thus, there is an urgent need to implement effective therapies that adequately lower and maintain BP. Newly incorporated into the American College of Cardiology/American Heart Association Guidelines for the Prevention and Management of High Blood Pressure (11), isometric handgrip (IHG) training is one such therapy (four, 2-min sustained squeezes at 30% of maximal effort, separated by 1-min rest, performed 3X/week on a computerized handgrip dynamometer). The high costs associated with the computerized devices (upwards of ~$400 CAD) may impede the main stream utilization of IHG training for BP management. As a first step in determining the effectiveness of an inexpensive (mechanical, ~$10 CAD) device to lower BP, this study compared systolic and diastolic BP responses to an acute bout of IHG performed using the mechanical and computerized devices. Young, healthy adults (N=12; 5 women; resting BP: 114/65 mmHg) randomly performed a bout of IHG on each device, with a 30-minute resting period between protocols. BP was acquired every minute using the Dinamap ProCare 200 BP Monitor. Across all contractions, the peak systolic BP response was similar between devices (all P > 0.05). With the exception of the 2nd contraction eliciting a higher BP response in the mechanical device (P = 0.013), diastolic BP changes were also similar (all P > 0.05). These findings suggest that more affordable devices may be an acceptable, low-cost alternative to the computerized IHG device, and that groundwork has been laid for a future training study. 1. Pan American Health Organization/World Health Organization. (2013). World health day: In the Americas, one in three adults has hypertension, the leading risk factor for death from cardiovascular disease. Retrieved from: http://www.paho.org/hq/index.php?option=com_content&view=article&id=8466&Itemid=1926&lang=en 2. World Health Organization. (2013). A global brief on hypertension: Silent killer, global public health crisis. Retrieved from: http://apps.who.int/iris/bitstream/10665/79059/1/WHO_DCO_WHD_2013.2_eng.pdf?ua=1 3. Joffres, M., Falaschetti, E., Gillespie, C., Robitaille, C., Loustalot, F., Poulter, N., … Campbell, N. (2013). 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