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567 results on '"Andresen D."'

1. Walking activity during ambulant cardiac rehabilitation is related to maximum working capacity, age, and smoking behavior

Author

Al Najem S, Groll A, Schmermund A, Nowak B, Voigtländer T, Kaltenbach U, Dohmann P, Andresen D, and Scharhag J

Subjects
Walking activity, cardiac rehabilitation, physical activity, fitness, step recommendation, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Sinann Al Najem,1,2 Andreas Groll,3,4 Axel Schmermund,5,6 Bernd Nowak,5,6 Thomas Voigtländer,5,6 Ulrike Kaltenbach,5 Peter Dohmann,5 Dietrich Andresen,7 Jürgen Scharhag2,8 1German Heart Foundation, Frankfurt, Germany; 2Institute of Sports and Preventive Medicine, Saarbrücken, Germany; 3Chair of Statistics, Georg August University, Göttingen, Germany; 4Faculty of Statistics, Technical University Dortmund, Dortmund, Germany; 5Cardioangiologisches Centrum Bethanien Herzwerk, Frankfurt, Germany; 6Bethanien Krankenhaus, Cardioangiologisches Centrum Bethanien, Frankfurt, Germany; 7Lutheran Hospital Hubertus, Berlin, Germany; 8Outpatients’ Clinic for Prevention, Rehabilitation and Sports Medicine, Technical University of Munich, Munich, Germany Background: A total of 6,500 to 8,000 steps per day are recommended for cardiovascular secondary prevention. The aim of this research was to examine how many steps per day patients achieve during ambulant cardiac rehabilitation (CR), and if there is a correlation between the number of steps and physical and cardiological parameters. Methods: In all, 192 stable CR patients were included and advised for sealed pedometry. The assessed parameters included maximum working capacity and heart rate, body mass index (BMI), New York Heart Association (NYHA) class, ejection fraction (EF), coronary artery disease status, beta-blocker medication, age, sex, smoking behavior, and laboratory parameters. A regularized regression approach called least absolute shrinkage and selection operator (LASSO) was used to detect a small set of explanatory variables associated with the response for steps per day. Based on these selected covariates, a sparse additive regression model was fitted. Results: The model noted that steps per day had a strong positive correlation with maximum working capacity (P=0.001), a significant negative correlation with higher age (P=0.01) and smoking (smoker: P40: 6,077±1,567). Conclusion: Walking activity during CR is reduced in patients who are unfit, older, smoke, or used to smoke. In addition to training recommendations, estimated steps per day during CR could be seen as a baseline orientation that helps patients to stay generally active or even to increase activity after CR. Keywords: step recommendation, steps/day in cardiac patients, pedometer

Published
2018

2. Sports Cardiology

Author

Al Najem S, Groll A, Schmermund A, Nowak B, Voigtländer T, Kaltenbach U, Dohmann P, Andresen D, and Scharhag J

Subjects
Sports medicine, RC1200-1245
Abstract

Background: Keeping patients active is an essential goal of cardiac rehabilitation (CR). This research aims to analyze the development of steps/day after CR.Methods: 126 adult, stable cardiac patients who had completed treatment for their acute condition, usually acute coronary syndrome or heart failure, were enrolled during CR and advised for daily step recording up to one year post CR. Mean number of steps during and for 3 weeks post CR were compared by paired t-test. Furthermore, influence of gender, age, smoking, NYHA, EF, BMI, day of the year, and length of time post CR on steps/day were estimated using a generalized additive regression model.Results: Compared to CR, steps/day increased on average by 925steps/day in the first 3 weeks (p0.05), whereas seasonal correlations existed, indicating a summer increase and a winter decline (p

Published
2020
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15. Antiarrhythmic drug therapy after catheter ablation for atrial fibrillation has no impact on recurrences, cardiovascular events and mortality – insights from the German Ablation Registry

Author

Schleberger, R, primary, Metzner, A, additional, Kuck, K H, additional, Andresen, D, additional, Willems, S, additional, Hoffmann, E, additional, Deneke, T, additional, Eckardt, L, additional, Brachmann, J, additional, Hochadel, M, additional, Senges, J, additional, and Rillig, A, additional

Published
2021
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21. The Atrial Fibrillation Ablation Pilot Study: an European Survey on Methodology and results of catheter ablation for atrial fibrillation conducted by the European Heart Rhythm Association

Author

Arbelo, Elena, Brugada, Josep, Hindricks, Gerhard, Maggioni, Aldo P., Tavazzi, Luigi, Vardas, Panos, Laroche, Cécile, Anselme, Frédéric, Inama, Giuseppe, Jais, Pierre, Kalarus, Zbigniew, Kautzner, Josef, Lewalter, Thorsten, Mairesse, Georges H., Perez-Villacastin, Julian, Riahi, Sam, Taborsky, Milos, Theodorakis, George, Trines, Serge A., Brugada, Josep, Arbelo, Elena, Hindriks, Gerhard, Maggioni, Aldo P., Morgan, John, Tavazzi, Luigi, Vardas, Panos, Alonso, Angeles, Ferrari, Roberto, Komajda, Michel, Tavazzi, Luigi, Wood, David, Vardas, Panos, Brugada, Josep, Mairesse, Georges, Taborsky, Milos, Kautzner, Josef, Lewalter, Thorsten, Riahi, Sam, Jais, Pierre, Anselme, Frédéric, Theodorakis, George, Inama, Giuseppe, Trines, Serge, Kalarus, Zbigniew, Villacastin, Julian Perez, Maggioni, Aldo P., Manini, Malika, Gracia, Gérard, Laroche, Cécile, Missiamenou, Viviane, Taylor, Charles, Konte, Marème, Fiorucci, Emanuela, Lefrancq, Elin Folkesson, Glémot, Myriam, McNeill, Patti-Ann, Bois, Timothée, Heidbüchel, H., Nuyens, D., Boland, J., Dinraths, V., Herzet, J.-M., Hoffer, E., Malmendier, D., Massoz, M., Pourbaix, S., Ballant, E., Blommaert, D., Deceuninck, O., Dormal, F., Xhaet, O., De Potter, T., Geelen, P., Derycker, K., Duytschaever, M., Tavernier, R., Vandekerckhove, Y., Vankats, D., Bulava, A., Hanis, J., Sitek, D., Blahova, M., Cihak, R., Hanyasova, L., Jansova, H., Peichl, P., Tanzerova, M., Wichterle, D., Duda, J., Haman, L., Parizek, P., Coling, L., Neuzil, P., Petru, J., Sediva, L., Skoda, J., Chovancik, J., Fiala, M., Neuwirth, R., Karlsdottir, A., Pehrson, S., Gerdes, C., Jensen, H.K., Lukac, P., Nielsen, J. C., Hansen, J., Johannessen, A., Hansen, P. S., Pedersen, A.K., Heath, F.P., Hjortshoj, S., Thogersen, A.M., Da Costa, A., Martel, I., Romeyer-Bouchard, C., Sadki, N., Schmid, A., Haissaguerre, M., Hocini, M., Knecht, S., Sacher, F., Ait Said, M., Cauchemez, B., Ledoux, F., Thomas, O., Cebron, J.-P., Decarsin, N., Gras, D., Hervouet, S., Durand, C., Durand-Dubief, A., Poty, H., Babuty, D., Pierre, B., Albenque, J.-P., Boveda, S., Combes, N., Mas, R., Hermida, J-S., Kubala, M., Godin, B., Savouré, A., Soublin, Y., Defaye, P., Jacon, P., Brigadeau, F., Corbut, S., Flament-Balzola, F., Kacet, S., Klug, D., Lacroix, D., Copie, X., Gilles, L., Hocine, Z., Paziaud, O., Piot, O., Crocq, C., Kaballu, G., Le Moal, V., Lotton, P., Mabo, P., Pavin, D., Andronache, M., De Chillou, C., Magnin-Poull, I., Deharo, J.-C., Durand, C., Franceschi, F., Peyrouse, E., Prevot, S., Etchegoin, M., Extramiana, F., Leenhardt, A., Messali, A., Heine, T., Schneider, A., Winter, N., Brachmann, J., Ritscher, G., Schertel-Gruenler, B., Simon, H., Sinha, A.-M., Turschner, O., Wystrach, A., Stemberg, M., Kuck, K.-H., Metzner, A., Tilz, R., Wissner, E., Heitmann, K., Willems, S., Andresen, D., Mueller, S., Volkmer, M., Schmidt, B., Kostopoulou, A., Livanis, E., Voudris, V., Efremidis, M., Letsas, K., Tsikrikas, S., Christoforatou, E., Ioannidis, P., Katsivas, A., Kourouklis, S., Andrikopoulos, G., Rassias, I., Tzeis, S., Dakos, G., Paraskevaidis, S., Stavropoulos, G., Theofilogiannakos, E., Vassilikos, V.P., Bongiorni, M.G., Zucchelli, G., Raviele, A., Themistoclakis, S., Pratola, C., Tritto, M., Della Bella, P., Mazzone, P., Moltrasio, M., Tondo, C., Calo, L., De Luca, L., Guarracini, F., Lioy, E., Dozza, L., Frigoli, E., Giannelli, L., Pappone, C., Saviano, M., Schiavina, G., Vicedomini, G.G., De Ponti, R., Doni, L. A., Marazzi, R., Salerno-Uriarte, J.A., Tamborini, C., Anselmino, M., Ferraris, F., Gaita, F., Bertaglia, E., Brandolino, G., Zoppo, F., De Groot, N., Janse, P., Jordaens, L., Pison, L., Roos, C., Van Gelder, I., Manusama, R., Meijer, A., Van der Voort, P., Trines, S., Compier, Marieke G., Kazmierczak, J., Kornacewicz-Jach, Z., Wielusinski, M., Baran, J., Kulakowski, P., Dzidowski, M., Fuglewicz, A., Nowak, K., Pruszkowska-Skrzep, P., Wozniak, A., Nowak, S., Trusz-Gluza, M., Almendral, J., Atienza, F., Castellanos, E., De Diego, C., Ortiz, M., Moreno Planas, J., Perez Castellano, N., Benezet, J., Farre Muncharaz, J., Rubio Campal, J.M., Hernandez Madrid, A., Matia, R., Arana, E., Pedrote, A., Cozar, R., Peinado, R., Valverde, I., Arbelo, E., Berruezo, A., Calvo, N., Guiu, E., Husseini, S., and Mont Girbau, L.

Published
2014
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24. Positionspapier zur Statintherapie

Author

Böhm, M., Laufs, U., Hamm, C., Andresen, D., Becker, H.-J., Borggrefe, M., Brachmann, J., Dietz, R., Ertl, G., Fleck, E., Gottwik, M.G., de Haan, F., Hoffmeister, H.M., Heusch, G., Meinertz, T., Osterspey, A., Silber, S., and Trappe, H.-J.

Published
2007
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26. Vancomycin exposure and acute kidney injury outcome: A Snapshot From the CAMERA2 Study

Author

Liu, J., Tong, S.Y.C., Davis, J.S., Rhodes, N.J., Scheetz, M.H., Anagostou, N., Andresen, D., Archuleta, S., Bak, N., Cass, A., Chatfield, M., Cheng, A., Davies, J., Davis, J., Dishon, Y., Dotel, R., Ferguson, P., Foo, H., Fowler, V., Ghosh, N., Gray, T., Guy, S., Holmes, N., Howden, B., Johnson, S., Kalimuddin, S., Lye, D., McBride, S., McKew, G., Meagher, N., Nelson, J., O’Sullivan, M., Paterson, D., Paul, M., Price, D., Ralph, A., Roberts, M., Robinson, O., Rogers, B., Runnegar, N., Smith, S., Sud, A., Tong, S., Tramontana, A., Van Hal, S., Walls, G., Warner, M., Yahav, D., Young, B., Liu, J., Tong, S.Y.C., Davis, J.S., Rhodes, N.J., Scheetz, M.H., Anagostou, N., Andresen, D., Archuleta, S., Bak, N., Cass, A., Chatfield, M., Cheng, A., Davies, J., Davis, J., Dishon, Y., Dotel, R., Ferguson, P., Foo, H., Fowler, V., Ghosh, N., Gray, T., Guy, S., Holmes, N., Howden, B., Johnson, S., Kalimuddin, S., Lye, D., McBride, S., McKew, G., Meagher, N., Nelson, J., O’Sullivan, M., Paterson, D., Paul, M., Price, D., Ralph, A., Roberts, M., Robinson, O., Rogers, B., Runnegar, N., Smith, S., Sud, A., Tong, S., Tramontana, A., Van Hal, S., Walls, G., Warner, M., Yahav, D., and Young, B.

Abstract

Among patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia from a prospective randomized clinical trial, acute kidney injury (AKI) rates increased with increasing vancomycin exposure, even within the therapeutic range. AKI was independently more common for the (flu)cloxacillin group. Day 2 vancomycin AUC ≥470 mg·h/L was significantly associated with AKI, independent of (flu)cloxacillin receipt.

Published
2020

27. Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex

Author

Dick, ALW, Zhao, Q, Crossin, R, Baker-Andresen, D, Li, X, Edson, J, Roeh, S, Marshall, V, Bredy, TW, Lawrence, AJ, Duncan, JR, Dick, ALW, Zhao, Q, Crossin, R, Baker-Andresen, D, Li, X, Edson, J, Roeh, S, Marshall, V, Bredy, TW, Lawrence, AJ, and Duncan, JR

Abstract

Inhalants containing the volatile solvent toluene are misused to induce euphoria or intoxication. Inhalant abuse is most common during adolescence and can result in cognitive impairments during an important maturational period. Despite evidence suggesting that epigenetic modifications may underpin the cognitive effects of inhalants, no studies to date have thoroughly investigated toluene-induced regulation of the transcriptome or discrete epigenetic modifications within the brain. To address this, we investigated effects of adolescent chronic intermittent toluene (CIT) inhalation on gene expression and DNA methylation profiles within the rat medial prefrontal cortex (mPFC), which undergoes maturation throughout adolescence and has been implicated in toluene-induced cognitive deficits. Employing both RNA-seq and genome-wide Methyl CpG Binding Domain (MBD) Ultra-seq analysis, we demonstrate that adolescent CIT inhalation (10 000 ppm for 1 h/day, 3 days/week for 4 weeks) induces both transient and persistent changes to the transcriptome and DNA methylome within the rat mPFC for at least 2 weeks following toluene exposure. We demonstrate for the first time that adolescent CIT exposure results in dynamic regulation of the mPFC transcriptome likely relating to acute inflammatory responses and persistent deficits in synaptic plasticity. These adaptations may contribute to the cognitive deficits associated with chronic toluene exposure and provide novel molecular targets for preventing long-term neurophysiological abnormalities following chronic toluene inhalation.

Published
2020

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