1,013 results on '"Andreini D"'
Search Results
2. Long-term risk assessment in athletes with ventricular arrhythmias: the key roles of arrhythmia morphology, complexity, and substrate
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Compagnucci, P, primary, Casella, M, additional, Narducci, M L, additional, Conte, E, additional, Cammarano, M, additional, Pelargonio, G, additional, Andreini, D, additional, Palmieri, V, additional, Lo Russo, G, additional, Pontone, G, additional, Natale, A, additional, Tondo, C, additional, Crea, F, additional, Zeppilli, P, additional, and Dello Russo, A, additional
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- 2024
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3. Physiological and angiographic outcomes of PCI in calcified lesions after rotational atherectomy or intravascular lithotripsy
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Gallinoro, E., Monizzi, G., Sonck, J., Candreva, A., Mileva, N., Nagumo, S., Munhoz, D., Buytaert, D., Mastrangelo, A., Andreini, D., Galli, S., Bartorelli, A.L., Barbato, E., De Bruyne, B., and Collet, C.
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- 2022
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4. Predictors Of Percutaneous Coronary Intervention Derived From Coronary Ct Angiography In Patients With Chronic Coronary Syndromes
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Belmonte, M., primary, Paolisso, P., additional, Gallinoro, E., additional, Bertolone, D., additional, Leone, A., additional, Sonck, J., additional, Vanderheyden, M., additional, Collet, C., additional, De Bruyne, B., additional, Andreini, D., additional, Penicka, M., additional, and Barbato, E., additional
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- 2024
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5. STRA-MI-VT (STereotactic RadioAblation by Multimodal Imaging for Ventricular Tachycardia): rationale and design of an Italian experimental prospective study
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Carbucicchio, C., Jereczek-Fossa, B. A., Andreini, D., Catto, V., Piperno, G., Conte, E., Cattani, F., Rondi, E., Vigorito, S., Piccolo, C., Bonomi, A., Gorini, A., Pepa, M., Mushtaq, S., Fassini, G., Moltrasio, M., Tundo, F., Marvaso, G., Veglia, F., Orecchia, R., Tremoli, E., and Tondo, C.
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- 2021
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6. Association of high-risk coronary atherosclerosis at CCTA with clinical and circulating biomarkers: Insight from CAPIRE study
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Maseri, A., Andreini, D., Berti, S., Canestrari, M., Casolo, G., Gabrielli, D., Latini, R., Magnoni, M., Marraccini, P., Masson, S., Moccetti, T., Modena, M.G., Pontone, G., Gaspari, F., Ferrari, S., Cannata, A., Stucchi, N., Fois, M., Bernasconi, R., Balconi, G., Vago, T., Letizia, T., Bottazzi, B., Leone, R., Suliman, I., Sommaruga, M., Gremigni, P., Olivieri, R., Pennacchietti, L., Magnacca, M., Rossi, M.G., Pasotti, E., Clemente, A., Mushtaq, S., Mauro, E., Rossi, R., Pigazzani, F., Faggioni, L., Ciardetti, M., Puppato, M., Conte, Edoardo, Andreini, Daniele, Magnoni, Marco, Masson, Serge, Mushtaq, Saima, Berti, Sergio, Canestrari, Mauro, Casolo, Giancarlo, Gabrielli, Domenico, Latini, Roberto, Marraccini, Paolo, Moccetti, Tiziano, Modena, Maria Grazia, Pontone, Gianluca, Gorini, Marco, Maggioni, Aldo P., and Maseri, Attilio
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- 2021
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7. Feasibility and accuracy of real-time 3D-holographic graft length measurement, a sub-study of the FAST-TRACK CABG trial
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Tsai, T, primary, Kageyama, S, additional, He, X C, additional, Onuma, Y, additional, Pompilio, G, additional, Andreini, D, additional, La Meir, M, additional, De Mey, J, additional, Puskas, J, additional, and Narula, J, additional
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- 2023
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8. Artificial intelligence analysis applied to facial features for prediction of high-risk coronary atherosclerosis at cardiac CT: the LOMBROSO Trial
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Conte, E, primary, Chiesa, M, additional, Melotti, E, additional, Marchetti, D, additional, Schillaci, M, additional, Mushtaq, S, additional, Baggiano, A, additional, Pontone, G, additional, Bartorelli, A, additional, and Andreini, D, additional
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- 2023
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9. Low HDL cholesterol and hyperglicemia are metabolic syndrome components associated with plaque progression in patients with chronic coronary syndrome: a PARADIGM study
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Neglia, D, primary, Caselli, C, additional, Maffei, E, additional, Lee, S E, additional, Sung, J M, additional, Andreini, D, additional, Al-Mallah, M, additional, Budoff, M J, additional, Gottlieb, I, additional, Hadamitzky, M, additional, Marques, H, additional, Min, J K, additional, Cademartiri, F, additional, and Chang, H J, additional
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- 2023
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10. PB0064 Involvement of Platelet Activation in Long COVID-19 Syndrome
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Brambilla, M., primary, Conti, M., additional, Becchetti, A., additional, Canzano, P., additional, Agostoni, P., additional, Pengo, M., additional, Tortorici, E., additional, Mancini, M., additional, Andreini, D., additional, Bonomi, A., additional, Parati, G., additional, and Camera, M., additional
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- 2023
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11. Quantification of calcium burden by coronary CT angiography compared to optical coherence tomography
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Monizzi, G., Sonck, J., Nagumo, S., Buytaert, D., Van Hoe, L., Grancini, L., Bartorelli, A. L., Vanhoenacker, P., Simons, P., Bladt, O., Wyffels, E., De Bruyne, B., Andreini, D., and Collet, C.
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- 2020
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12. Current trends in patients with chronic total occlusions undergoing coronary CT angiography
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Opolski, MP, Hartaigh, BO, Berman, DS, Budoff, MJ, Achenbach, S, Al-Mallah, M, Andreini, D, Cademartiri, F, Chang, HJ, Chinnaiyan, K, Chow, BJW, Hadamitzky, M, Hausleiter, J, Feuchtner, G, Kim, YJ, Kaufmann, PA, Leipsic, J, Maffei, E, Pontone, G, Raff, G, Shaw, LJ, Villines, TC, and Min, JK
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Cardiovascular System & Hematology ,Cardiorespiratory Medicine and Haematology - Abstract
Objective: Data describing the prevalence, characteristics and management of coronary chronic total occlusions (CTOs) in patients undergoing coronary CT angiography (CCTA) have not been reported. The purpose of this study was to determine the prevalence, characteristics and treatment strategies of CTO identified by CCTA. Methods: We identified 23 745 patients who underwent CCTA for suspected coronary artery disease (CAD) from the prospective international CCTA registry. Baseline clinical data were collected, and allocation to early coronary revascularisation performed within 90 days of CCTA was determined. Multivariable hierarchical mixed-effects logistic regression reporting OR with 95% CI was performed. Results: The prevalence of CTO was 1.4% (342/23 745) in all patients and 6.2% in patients with obstructive CAD (≥50% stenosis). The presence of CTO was independently associated with male sex (OR 3.12, 95% CI 2.39 to 4.08, p
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- 2015
13. Cardiac magnetic resonance for ischaemia and viability detection. Guiding patient selection to revascularization in coronary chronic total occlusions: The CARISMA_CTO study design
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Pica, S., Di Giovine, G., Bollati, M., Testa, L., Bedogni, F., Camporeale, A., Pontone, G., Andreini, D., Monti, L., Gasparini, G., Grancini, L., Secco, G.G., Maestroni, A., Ambrogi, F., Milani, V., and Lombardi, M.
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- 2018
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14. Feasibility And Accuracy Of Real-time 3d-holographic Graft Length Measurement, A Substudy Of The Fasttrack Cabg Trial
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Tsai, T., primary, Kageyama, S., additional, He, X., additional, Onuma, Y., additional, Pompilio, G., additional, Andreini, D., additional, La Meir, M., additional, De Mey, J., additional, Puskas, J., additional, Narula, J., additional, and Serruys, P., additional
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- 2023
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15. Predictors Of Percutaneous Coronary Intervention Derived From Coronary Ct Angiography In Patients With Chronic Coronary Syndromes
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Belmonte, M., primary, Paolisso, P., additional, Gallinoro, E., additional, Bertolone, D., additional, Caglioni, S., additional, Leone, A., additional, De Colle, C., additional, Bermpeis, K., additional, Storozhenko, T., additional, Mileva, N., additional, Sonck, J., additional, Wyffels, E., additional, Venderheyden, M., additional, Collet, C., additional, De Bruyne, B., additional, Andreini, D., additional, Penicka, M., additional, and Barbato, E., additional
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- 2023
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16. Diagnostic Accuracy Of Dynamic Stress Myocardial Ct Perfusion As Compared With Invasive Coronary Physiology Assessment In Patients With Suspected In-stent Restenosis Or Cad Progression: Results Of Advantage 2 Study
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Mushtaq, S., primary, Andreini, D., additional, Conte, E., additional, baggiano, A., additional, trabattoni, D., additional, maragna, R., additional, fazzari, F., additional, collet, C., additional, belmonte, M., additional, LoRusso, G., additional, Bartorelli, A., additional, annoni, A., additional, and pontone, G., additional
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- 2023
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17. Comparison Of The Diagnostic Accuracy Of Dynamic Ct Perfusion And Cardiac Cmr With Quantitative Perfusion: A Subanalysis Of Advantage Ii Study
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Mushtaq, S., primary, Andreini, D., additional, gaudenzi asinelli, M., additional, junod, D., additional, conte, E., additional, baggiano, A., additional, annoni, A., additional, maragna, R., additional, fazzari, F., additional, wang, S., additional, and pontone, G., additional
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- 2023
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18. Multimodality imaging for negative T waves among athletes with normal transthoracic echocardiography: prevalence and prognosis of structural heart disease
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Conte, E, primary, Pizzamiglio, F, additional, Dessanai, M, additional, Mushtaq, S, additional, Schillaci, M, additional, Marchetti, D, additional, Melotti, E, additional, Volpato, V, additional, Tondo, C, additional, Bartorelli, A, additional, and Andreini, D, additional
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- 2023
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19. SPREAD multicentre study: sports practice and its effect on bicuspid aortic valve disease
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D'ascenzi, F, primary, Cavigli, L, additional, Claessen, G, additional, Van Craenenbroeck, E, additional, Cavarretta, E, additional, D'andrea, A, additional, Sanz De La Garza, M, additional, Eijsvogels, T, additional, Halle, M, additional, Andreini, D, additional, Moreo, A, additional, Schreurs, B, additional, Sitges, M, additional, Stefani, L, additional, and Pelliccia, A, additional
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- 2023
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20. P153 A DEEP–LEARNING APPROACH FOR SCAR DETECTION IN EARLY CONTRAST–ENHANCED CARDIAC COMPUTED TOMOGRAPHY IMAGES
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Penso, M, primary, Babbaro, M, additional, Guglielmo, M, additional, Baggiano, A, additional, Moccia, S, additional, Pepi, M, additional, Fusini, L, additional, Carerj, L, additional, Andreini, D, additional, Caiani, E, additional, and Pontone, G, additional
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- 2023
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21. Myocardial Fibrosis at Cardiac MRI Helps Predict Adverse Clinical Outcome in Patients with Mitral Valve Prolapse
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Figliozzi, S, Georgiopoulos, G, Lopes, P, Bauer, K, Moura-Ferreira, S, Tondi, L, Mushtaq, S, Censi, S, Pavon, A, Bassi, I, Servato, M, Teske, A, Biondi, F, Filomena, D, Pica, S, Torlasco, C, Muraru, D, Monney, P, Quattrocchi, G, Maestrini, V, Agati, L, Monti, L, Pedrotti, P, Vandenberk, B, Squeri, A, Lombardi, M, Ferreira, A, Schwitter, J, Aquaro, G, Chiribiri, A, Rodríguez Palomares, J, Yilmaz, A, Andreini, D, Florian, A, Leiner, T, Abecasis, J, Badano, L, Bogaert, J, Masci, P, Figliozzi, Stefano, Georgiopoulos, Georgios, Lopes, Pedro M, Bauer, Klemens B, Moura-Ferreira, Sara, Tondi, Lara, Mushtaq, Saima, Censi, Stefano, Pavon, Anna Giulia, Bassi, Ilaria, Servato, Maria Luz, Teske, Arco J, Biondi, Federico, Filomena, Domenico, Pica, Silvia, Torlasco, Camilla, Muraru, Denisa, Monney, Pierre, Quattrocchi, Giuseppina, Maestrini, Viviana, Agati, Luciano, Monti, Lorenzo, Pedrotti, Patrizia, Vandenberk, Bert, Squeri, Angelo, Lombardi, Massimo, Ferreira, António M, Schwitter, Juerg, Aquaro, Giovanni Donato, Chiribiri, Amedeo, Rodríguez Palomares, José F, Yilmaz, Ali, Andreini, Daniele, Florian, Anca, Leiner, Tim, Abecasis, João, Badano, Luigi, Bogaert, Jan, Masci, Pier-Giorgio, Figliozzi, S, Georgiopoulos, G, Lopes, P, Bauer, K, Moura-Ferreira, S, Tondi, L, Mushtaq, S, Censi, S, Pavon, A, Bassi, I, Servato, M, Teske, A, Biondi, F, Filomena, D, Pica, S, Torlasco, C, Muraru, D, Monney, P, Quattrocchi, G, Maestrini, V, Agati, L, Monti, L, Pedrotti, P, Vandenberk, B, Squeri, A, Lombardi, M, Ferreira, A, Schwitter, J, Aquaro, G, Chiribiri, A, Rodríguez Palomares, J, Yilmaz, A, Andreini, D, Florian, A, Leiner, T, Abecasis, J, Badano, L, Bogaert, J, Masci, P, Figliozzi, Stefano, Georgiopoulos, Georgios, Lopes, Pedro M, Bauer, Klemens B, Moura-Ferreira, Sara, Tondi, Lara, Mushtaq, Saima, Censi, Stefano, Pavon, Anna Giulia, Bassi, Ilaria, Servato, Maria Luz, Teske, Arco J, Biondi, Federico, Filomena, Domenico, Pica, Silvia, Torlasco, Camilla, Muraru, Denisa, Monney, Pierre, Quattrocchi, Giuseppina, Maestrini, Viviana, Agati, Luciano, Monti, Lorenzo, Pedrotti, Patrizia, Vandenberk, Bert, Squeri, Angelo, Lombardi, Massimo, Ferreira, António M, Schwitter, Juerg, Aquaro, Giovanni Donato, Chiribiri, Amedeo, Rodríguez Palomares, José F, Yilmaz, Ali, Andreini, Daniele, Florian, Anca, Leiner, Tim, Abecasis, João, Badano, Luigi, Bogaert, Jan, and Masci, Pier-Giorgio
- Abstract
Background: Patients with mitral valve prolapse (MVP) may develop adverse outcomes even in the absence of mitral regurgitation or left ventricular (LV) dysfunction. Purpose: To investigate the prognostic value of mitral annulus disjunction (MAD) and myocardial fibrosis at late gadolinium enhancement (LGE) cardiac MRI in patients with MVP without moderate-to-severe mitral regurgitation or LV dysfunction. Materials and Methods: In this longitudinal retrospective study, 118 144 cardiac MRI studies were evaluated between October 2007 and June 2020 at 15 European tertiary medical centers. Follow-up was from the date of cardiac MRI examination to June 2020; the minimum and maximum follow-up intervals were 6 months and 156 months, respectively. Patients were excluded if at least one of the following conditions was present: cardiomyopathy, LV ejection fraction less than 40%, ischemic heart disease, congenital heart disease, inflammatory heart disease, moderate or worse mitral regurgitation, participation in competitive sport, or electrocardiogram suggestive of channelopathies. In the remainder, cardiac MRI studies were reanalyzed, and patients were included if they were aged 18 years or older, MVP was diagnosed at cardiac MRI, and clinical information and electrocardiogram monitoring were available within 3 months from cardiac MRI examination. The end point was a composite of adverse outcomes: sustained ventricular tachycardia (VT), sudden cardiac death (SCD), or unexplained syncope. Multivariable Cox regression analysis was performed. Results: A total of 474 patients (mean age, 47 years ± 16 [SD]; 244 women) were included. Over a median follow-up of 3.3 years, 18 patients (4%) reached the study end point. LGE presence (hazard ratio, 4.2 [95% CI: 1.5, 11.9]; P = .006) and extent (hazard ratio, 1.2 per 1% increase [95% CI: 1.1, 1.4]; P = .006), but not MAD presence (P = .89), were associated with clinical outcome. LGE presence had incremental prognostic value over MVP severi
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- 2023
22. Mercaptoalbumin Is Associated with Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting
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Brioschi, M, Gianazza, E, Andreini, D, Mushtaq, S, Cavallotti, L, Veglia, F, Tedesco, C, Colombo, G, Pepi, M, Polvani, G, Tremoli, E, Parolari, A, Banfi, C, Brioschi M., Gianazza E., Andreini D., Mushtaq S., Cavallotti L., Veglia F., Tedesco C. C., Colombo G. I., Pepi M., Polvani G., Tremoli E., Parolari A., Banfi C., Brioschi, M, Gianazza, E, Andreini, D, Mushtaq, S, Cavallotti, L, Veglia, F, Tedesco, C, Colombo, G, Pepi, M, Polvani, G, Tremoli, E, Parolari, A, Banfi, C, Brioschi M., Gianazza E., Andreini D., Mushtaq S., Cavallotti L., Veglia F., Tedesco C. C., Colombo G. I., Pepi M., Polvani G., Tremoli E., Parolari A., and Banfi C.
- Abstract
Coronary artery bypass graft (CABG) surgery still represents the gold standard for patients with complex multivessel coronary artery disease. However, graft occlusion still occurs in a significant proportion of CABG conduits, and oxidative stress is currently considered to be a potential contributor. Human serum albumin (HSA) represents the main antioxidant in plasma through its reduced amino acid Cys34, which can efficiently scavenge several oxidants. In a nested case-control study including 36 patients with occluded grafts and 38 age- and sex-matched patients without occlusion, we assessed the levels of the native mercaptoalbumin (HSA-SH) and oxidized thiolated form of albumin (Thio-HSA) in relation with graft occlusion within 5 years after CABG. We found that the plasma level of preoperative HSA-SH was significantly lower in patients with occluded graft at 5 years follow-up than in patients with graft patency. Furthermore, low HSA-SH remained independently associated with graft occlusion even after adjusting for preoperative D-dimer, a well-known marker of activated coagulation recently found to be associated with graft occlusion. In conclusion, the preoperative level of HSA-SH is independently associated with graft occlusion in CABG and represents a measurable and potentially druggable predictor.
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- 2022
23. Diagnostic performance of deep learning algorithm for analysis of computed tomography myocardial perfusion
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Muscogiuri, G, Chiesa, M, Baggiano, A, Spadafora, P, De Santis, R, Guglielmo, M, Scafuri, S, Fusini, L, Mushtaq, S, Conte, E, Annoni, A, Formenti, A, Mancini, M, Ricci, F, Ariano, F, Spiritigliozzi, L, Babbaro, M, Mollace, R, Maragna, R, Giacari, C, Andreini, D, Guaricci, A, Colombo, G, Rabbat, M, Pepi, M, Sardanelli, F, Pontone, G, Muscogiuri G, Chiesa M, Baggiano A, Spadafora P, De Santis R, Guglielmo M, Scafuri S, Fusini L, Mushtaq S, Conte E, Annoni A, Formenti A, Mancini ME, Ricci F, Ariano FP, Spiritigliozzi L, Babbaro M, Mollace R, Maragna R, Giacari CM, Andreini D, Guaricci AI, Colombo GI, Rabbat MG, Pepi M, Sardanelli F, Pontone G., Muscogiuri, G, Chiesa, M, Baggiano, A, Spadafora, P, De Santis, R, Guglielmo, M, Scafuri, S, Fusini, L, Mushtaq, S, Conte, E, Annoni, A, Formenti, A, Mancini, M, Ricci, F, Ariano, F, Spiritigliozzi, L, Babbaro, M, Mollace, R, Maragna, R, Giacari, C, Andreini, D, Guaricci, A, Colombo, G, Rabbat, M, Pepi, M, Sardanelli, F, Pontone, G, Muscogiuri G, Chiesa M, Baggiano A, Spadafora P, De Santis R, Guglielmo M, Scafuri S, Fusini L, Mushtaq S, Conte E, Annoni A, Formenti A, Mancini ME, Ricci F, Ariano FP, Spiritigliozzi L, Babbaro M, Mollace R, Maragna R, Giacari CM, Andreini D, Guaricci AI, Colombo GI, Rabbat MG, Pepi M, Sardanelli F, and Pontone G.
- Abstract
Purpose: To evaluate the diagnostic accuracy of a deep learning (DL) algorithm predicting hemodynamically significant coronary artery disease (CAD) by using a rest dataset of myocardial computed tomography perfusion (CTP) as compared to invasive evaluation. Methods: One hundred and twelve consecutive symptomatic patients scheduled for clinically indicated invasive coronary angiography (ICA) underwent CCTA plus static stress CTP and ICA with invasive fractional flow reserve (FFR) for stenoses ranging between 30 and 80%. Subsequently, a DL algorithm for the prediction of significant CAD by using the rest dataset (CTP-DLrest) and stress dataset (CTP-DLstress) was developed. The diagnostic accuracy for identification of significant CAD using CCTA, CCTA + CTP stress, CCTA + CTP-DLrest, and CCTA + CTP-DLstress was measured and compared. The time of analysis for CTP stress, CTP-DLrest, and CTP-DLStress was recorded. Results: Patient-specific sensitivity, specificity, NPV, PPV, accuracy, and area under the curve (AUC) of CCTA alone and CCTA + CTPStress were 100%, 33%, 100%, 54%, 63%, 67% and 86%, 89%, 89%, 86%, 88%, 87%, respectively. Patient-specific sensitivity, specificity, NPV, PPV, accuracy, and AUC of CCTA + DLrest and CCTA + DLstress were 100%, 72%, 100%, 74%, 84%, 96% and 93%, 83%, 94%, 81%, 88%, 98%, respectively. All CCTA + CTP stress, CCTA + CTP-DLRest, and CCTA + CTP-DLStress significantly improved detection of hemodynamically significant CAD compared to CCTA alone (p < 0.01). Time of CTP-DL was significantly lower as compared to human analysis (39.2 ± 3.2 vs. 379.6 ± 68.0 s, p < 0.001). Conclusion: Evaluation of myocardial ischemia using a DL approach on rest CTP datasets is feasible and accurate. This approach may be a useful gatekeeper prior to CTP stress..
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- 2022
24. Computed tomography predictors of structural valve degeneration in patients undergoing transcatheter aortic valve implantation with balloon-expandable prostheses
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Guglielmo, M, Fusini, L, Muratori, M, Tamborini, G, Mantegazza, V, Andreini, D, Annoni, A, Babbaro, M, Baggiano, A, Conte, E, Carriero, S, Formenti, A, Guaricci, A, Mancini, E, Mollace, R, Muscogiuri, G, Mushtaq, S, Ricci, F, Rossi, A, Scafuri, S, Alushi, B, Cau, C, Cau, R, Cesarano, M, Saba, L, Rabbat, M, Pepi, M, Pontone, G, Guglielmo M., Fusini L., Muratori M., Tamborini G., Mantegazza V., Andreini D., Annoni A., Babbaro M., Baggiano A., Conte E., Carriero S., Formenti A., Guaricci A. I., Mancini E., Mollace R., Muscogiuri G., Mushtaq S., Ricci F., Rossi A., Scafuri S., Alushi B., Cau C., Cau R., Cesarano M., Saba L., Rabbat M., Pepi M., Pontone G., Guglielmo, M, Fusini, L, Muratori, M, Tamborini, G, Mantegazza, V, Andreini, D, Annoni, A, Babbaro, M, Baggiano, A, Conte, E, Carriero, S, Formenti, A, Guaricci, A, Mancini, E, Mollace, R, Muscogiuri, G, Mushtaq, S, Ricci, F, Rossi, A, Scafuri, S, Alushi, B, Cau, C, Cau, R, Cesarano, M, Saba, L, Rabbat, M, Pepi, M, Pontone, G, Guglielmo M., Fusini L., Muratori M., Tamborini G., Mantegazza V., Andreini D., Annoni A., Babbaro M., Baggiano A., Conte E., Carriero S., Formenti A., Guaricci A. I., Mancini E., Mollace R., Muscogiuri G., Mushtaq S., Ricci F., Rossi A., Scafuri S., Alushi B., Cau C., Cau R., Cesarano M., Saba L., Rabbat M., Pepi M., and Pontone G.
- Abstract
Objectives: Computed tomography (CT) provides excellent anatomy assessment of the aortic annulus (AoA) and is utilized for pre-procedural planning of transcatheter aortic valve implantation (TAVI). We sought to investigate if geometrical characteristics of the AoA determined by CT may represent predictors of structural valve degeneration (SVD) in patients undergoing TAVI with balloon-expandable valves. Methods: This is a retrospective study on 124 consecutive patients (mean age: 79 ± 7 years; female: 61%) undergoing balloon-expandable TAVI prospectively enrolled in a registry. AoA maximum diameter (Dmax), minimum diameter (Dmin), and area were assessed using pre-procedural CT. SVD was identified during follow-up with transthoracic echocardiography documenting structural prosthetic valve abnormalities with or without hemodynamic changes. Results: The mean follow-up was 5.9 ± 1.7 years. SVD was found in 48 out of 124 patients (38%). AoA Dmax, Dmin, and area were significantly smaller in patients with SVD compared to patients without SVD (25.6 ± 2.2 mm vs. 27.1 ± 2.8 mm, p = 0.012; 20.5 ± 2.1 mm vs. 21.8 ± 2.1 mm, p = 0.001 and 419 ± 77 mm2 vs. 467 ± 88 mm2, p = 0.002, respectively). At univariable analysis, female sex, BSA, 23-mm prosthetic valve size, Dmax < 27.1 mm, and a Dmin < 19.9 mm were associated with SVD, whereas at multivariable analysis, only Dmin < 19.9 mm (OR = 2.873, 95% CI: 1.191–6.929, p = 0.019) and female sex (OR = 2.659, 95% CI: 1.095–6.458, p = 0.031) were independent predictors of SVD. Conclusions: Female sex and AoA Dmin < 19.9 mm are associated with SVD in patients undergoing TAVI with balloon-expandable valves. When implanting large prostheses in order to avoid paraprosthetic regurgitation, caution should be observed due to the risk of excessive stretching of the AoA Dmin, which may play a role in SVD. Key Points: • Long-term durability is a concern for transcatheter aortic valve bioprosthesis. • CT provides an excellent assessment
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- 2022
25. Plaque assessment by coronary CT angiography may predict cardiac events in high risk and very high risk diabetic patients: A long-term follow-up study
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Andreini, D, Conte, E, Mushtaq, S, Magatelli, M, Traversari, F, Gigante, C, Belmonte, M, Gaudenzi-Asinelli, M, Annoni, A, Formenti, A, Mancini, M, Guglielmo, M, Baggiano, A, Melotti, E, Muscogiuri, G, Rondinelli, M, Pontone, G, Bartorelli, A, Pepi, M, Genovese, S, Andreini D, Conte E, Mushtaq S, Magatelli M, Traversari F, Gigante C, Belmonte M, Gaudenzi-Asinelli M, Annoni A, Formenti A, Mancini ME, Guglielmo M, Baggiano A, Melotti E, Muscogiuri G, Rondinelli M, Pontone G, Bartorelli AL, Pepi M, Genovese S., Andreini, D, Conte, E, Mushtaq, S, Magatelli, M, Traversari, F, Gigante, C, Belmonte, M, Gaudenzi-Asinelli, M, Annoni, A, Formenti, A, Mancini, M, Guglielmo, M, Baggiano, A, Melotti, E, Muscogiuri, G, Rondinelli, M, Pontone, G, Bartorelli, A, Pepi, M, Genovese, S, Andreini D, Conte E, Mushtaq S, Magatelli M, Traversari F, Gigante C, Belmonte M, Gaudenzi-Asinelli M, Annoni A, Formenti A, Mancini ME, Guglielmo M, Baggiano A, Melotti E, Muscogiuri G, Rondinelli M, Pontone G, Bartorelli AL, Pepi M, and Genovese S.
- Abstract
Background and aims: The aim of the present study is to evaluate whether advanced coronary atherosclerosis analysis by CCTA may improve prognostic stratification among diabetic patients at high cardiovascular risk (CV risk). Methods and results: The study population consisted of 265 consecutive diabetic patients at high CV risk who underwent CCTA for suspected CAD between January 2011 and December 2016. For every patients both traditional and advanced, qualitative and quantitative coronary plaque analysis were performed. The occurrence of cardiac death, ACS, and non-urgent revascularization were recorded at follow-up. Among the 265 patients enrolled, 21 were lost to follow-up, whereas 244 (92%) had a complete follow-up (mean 45 ± 22 months) and were classified at high (n = 67) or very high cardiovascular risk (n = 177), according to ESC Guidelines. A total of 63 events were recorded (3 Cardiac Death, 3 NSTEMI, 8 unstable angina, 36 late non-urgent revascularization and 13 non-cardiac death) in 57 different patients. Elevated fibro-fatty plaque volume was the only predictor of events over age, gender and traditional risk factor when ACS and MACE were considered as end-points [HR (95% CI) 6.01 (1.65–21.87), p = 0.006 and 3.46 (2.00–5.97); p < 0.001]. Conclusion: The present study confirms the prognostic role of advance coronary atherosclerosis evaluation beyond risk factors and stenosis severity, even in diabetics. Despite the very high cardiovascular risk of study population, a not negligible portion (23%) of patients exhibited totally normal coronaries.
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- 2022
26. Different Phases of Disease in Lymphocytic Myocarditis: Clinical and Electrophysiological Characteristics
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Casella, M., Gasperetti, A., Compagnucci, P., Narducci, M. L., Pelargonio, G., Catto, V., Carbucicchio, C., Bencardino, G., Conte, E., Schicchi, N., Andreini, D., Pontone, G., Giovagnoni, A., Rizzo, S., Inzani, F., Basso, C., Natale, A., Tondo, C., Russo, A. D., and Crea, F.
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cardiac magnetic resonance imaging ,endomyocardial biopsy ,ventricular arrhythmias ,substrate characterization ,electroanatomical mapping ,myocarditis - Published
- 2023
27. A deep-learning approach for scar detection in early contrast-enhanced cardiac computed tomography images
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Penso, M, primary, Babbaro, M, additional, Moccia, S, additional, Baggiano, A, additional, Pepi, M, additional, Andreini, D, additional, Caiani, E G, additional, and Pontone, G, additional
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- 2022
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28. Comparison of the SYNTAX score 2020 based on Coronary Artery Computed Tomography (CCTA) with Invasive Coronary Angiography (ICA)
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Masuda, S, primary, Kageyama, S, additional, Kotoku, N, additional, Ninomiya, K, additional, Schneider, U, additional, Doenst, T, additional, Tanaka, K, additional, Mey, J D, additional, Lameir, M, additional, Mushtaq, S, additional, Bartorelli, A, additional, Pompilio, G, additional, Andreini, D, additional, Onuma, Y, additional, and Serruys, P W, additional
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- 2022
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29. Diagnostic and prognostic role of cardiac magnetic resonance in patients with MINOCA
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Mileva, N, primary, Paolisso, P, additional, Gallinoro, E, additional, Bergamaschi, L, additional, Pizzi, C, additional, Barbato, E, additional, Penicka, M, additional, Andreini, D, additional, and Vassilev, D I, additional
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- 2022
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30. Long COVID-19 syndrome: association of cardiopulmonary impairment with a persistent platelet activation
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Camera, M, primary, Brambilla, M, additional, Canzano, P, additional, Becchetti, A, additional, Conti, M, additional, Agostoni, P G, additional, Pengo, M, additional, Tortorici, E, additional, Mancini, M E, additional, Andreini, D, additional, Bonomi, A, additional, and Parati, G F, additional
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- 2022
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31. Deep learning applied to facial features for prediction of high risk coronary atherosclerosis at cardiac CT: preliminary data from LOMBROSO Trial
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Conte, E, primary, Chiesa, M, additional, Mushtaq, S, additional, Schillaci, M, additional, Marchetti, D, additional, Baggiano, A, additional, Volpe, A, additional, Colombo, G, additional, Pompilio, G, additional, Bartorelli, A, additional, Pontone, G, additional, and Andreini, D, additional
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- 2022
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32. Additional diagnostic value of cardiac magnetic resonance feature tracking in patients with biopsy-proven arrhythmogenic cardiomyopathy
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Muscogiuri, G, Fusini, L, Ricci, F, Sicuso, R, Guglielmo, M, Baggiano, A, Gasperetti, A, Casella, M, Mushtaq, S, Conte, E, Annoni, A, Formenti, A, Mancini, M, Babbaro, M, Mollace, R, Collevecchio, A, Scafuri, S, Kukavica, D, Andreini, D, Basso, C, Rizzo, S, De Gaspari, M, Priori, S, Dello Russo, A, Tondo, C, Pepi, M, Sommariva, E, Rabbat, M, Guaricci, A, Pontone, G, Muscogiuri G., Fusini L., Ricci F., Sicuso R., Guglielmo M., Baggiano A., Gasperetti A., Casella M., Mushtaq S., Conte E., Annoni A., Formenti A., Mancini M. E., Babbaro M., Mollace R., Collevecchio A., Scafuri S., Kukavica D., Andreini D., Basso C., Rizzo S., De Gaspari M., Priori S., Dello Russo A., Tondo C., Pepi M., Sommariva E., Rabbat M., Guaricci A. I., Pontone G., Muscogiuri, G, Fusini, L, Ricci, F, Sicuso, R, Guglielmo, M, Baggiano, A, Gasperetti, A, Casella, M, Mushtaq, S, Conte, E, Annoni, A, Formenti, A, Mancini, M, Babbaro, M, Mollace, R, Collevecchio, A, Scafuri, S, Kukavica, D, Andreini, D, Basso, C, Rizzo, S, De Gaspari, M, Priori, S, Dello Russo, A, Tondo, C, Pepi, M, Sommariva, E, Rabbat, M, Guaricci, A, Pontone, G, Muscogiuri G., Fusini L., Ricci F., Sicuso R., Guglielmo M., Baggiano A., Gasperetti A., Casella M., Mushtaq S., Conte E., Annoni A., Formenti A., Mancini M. E., Babbaro M., Mollace R., Collevecchio A., Scafuri S., Kukavica D., Andreini D., Basso C., Rizzo S., De Gaspari M., Priori S., Dello Russo A., Tondo C., Pepi M., Sommariva E., Rabbat M., Guaricci A. I., and Pontone G.
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Background: We aim to evaluate the value of Cardiac magnetic resonance (CMR) feature tracking (CMR-FT) in addition to Task Force Criteria(TFC) in patients with (arrhythmogenic cardiomyopathy) AC biopsy-proved. Methods: Thirty-five patients with AC histologically proven who performed CMR with late gadolinium enhancement (LGE) acquisition were enrolled. The study population was divided in Group1 (negative CMR TFC and LV ejection fraction≥55%) and Group2 (positive CMR TFC and/or LVEF<55%) and compared to an age and gender-matched control group. CMR datasets of all patients were analyzed to calculate LV indexed end-diastolic (LVEDi) and end-systolic (LVESi) volumes and RV indexed end-diastolic (RVEDi) and end-systolic (RVESi) volumes, both LV ejection fraction (LVEF) and RV ejection fraction (RVEF). Moreover, LV and RV global longitudinal (GLS), circumferential (GCS) and radial (GRS) strain were measured. Results: The AC patients showed both higher LVEDi (p:0.002) and RVEDi (p:0.017) and lower LVEF (p: 0.016) as compared to control patients. Moreover, AC patients showed impaired LV-GLS (p < 0.001), LV-GRS (p < 0.001), LV-GCS (p < 0.001) and RV-GRS (p:0.026) as compared to control subjects. Group1 patients showed a significant reduction of LV-GRS (p < 0.05) and LV-GCS p < 0.01) as compared to control subjects. At univariate analysis LV-GCS was the most discriminatory parameter between Group1 vs heathy subjects with an optimal cut-off of −15.8 (Sensitivity: 74%; Specificity: 10%). Conclusions: In patients with AC biopsy-proven, CMR-FT could improve the diagnostic yield in the subset of patients who results negative for imaging TFC criteria resulting as useful gatekeeper for indication of myocardial biopsy in case of equivocal clinical and imaging presentation.
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- 2021
33. Platelet and Endothelial Activation as Potential Mechanisms Behind the Thrombotic Complications of COVID-19 Patients
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Canzano, P, Brambilla, M, Porro, B, Cosentino, N, Tortorici, E, Vicini, S, Poggio, P, Cascella, A, Pengo, M, Veglia, F, Fiorelli, S, Bonomi, A, Cavalca, V, Trabattoni, D, Andreini, D, Omodeo Sale, E, Parati, G, Tremoli, E, Camera, M, Canzano P., Brambilla M., Porro B., Cosentino N., Tortorici E., Vicini S., Poggio P., Cascella A., Pengo M., Veglia F., Fiorelli S., Bonomi A., Cavalca V., Trabattoni D., Andreini D., Omodeo Sale E., Parati G., Tremoli E., Camera M., Canzano, P, Brambilla, M, Porro, B, Cosentino, N, Tortorici, E, Vicini, S, Poggio, P, Cascella, A, Pengo, M, Veglia, F, Fiorelli, S, Bonomi, A, Cavalca, V, Trabattoni, D, Andreini, D, Omodeo Sale, E, Parati, G, Tremoli, E, Camera, M, Canzano P., Brambilla M., Porro B., Cosentino N., Tortorici E., Vicini S., Poggio P., Cascella A., Pengo M., Veglia F., Fiorelli S., Bonomi A., Cavalca V., Trabattoni D., Andreini D., Omodeo Sale E., Parati G., Tremoli E., and Camera M.
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The authors hypothesized that the cytokine storm described in COVID-19 patients may lead to consistent cell-based tissue factor (TF)-mediated activation of coagulation, procoagulant microvesicles (MVs) release, and massive platelet activation. COVID-19 patients have higher levels of TF+ platelets, TF+ granulocytes, and TF+ MVs than healthy subjects and coronary artery disease patients. Plasma MV-associated thrombin generation is present in prophylactic anticoagulated patients. A sustained platelet activation in terms of P-selectin expression and platelet–leukocyte aggregate formation, and altered nitric oxide/prostacyclin synthesis are also observed. COVID-19 plasma, added to the blood of healthy subjects, induces platelet activation similar to that observed in vivo. This effect was blunted by pre-incubation with tocilizumab, aspirin, or a P2Y12 inhibitor.
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- 2021
34. The hidden interplay between sex and COVID-19 mortality: the role of cardiovascular calcification
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Cereda, A, Toselli, M, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Mangieri, A, Khokhar, A, Campo, G, Scoccia, A, Bertini, M, Loffi, M, Sergio, P, Andreini, D, Pontone, G, Iannopollo, G, Nannini, T, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Vignali, L, Sverzellati, N, Iannaccone, M, Vaudano, P, Sangiorgi, G, Turchio, P, Monello, A, Tumminello, G, Maggioni, A, Rapezzi, C, Colombo, A, Giannini, F, Esposito, A, Cereda A., Toselli M., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Mangieri A., Khokhar A., Campo G., Scoccia A., Bertini M., Loffi M., Sergio P., Andreini D., Pontone G., Iannopollo G., Nannini T., Ippolito D., Bellani G., Patelli G., Besana F., Vignali L., Sverzellati N., Iannaccone M., Vaudano P. G., Sangiorgi G. M., Turchio P., Monello A., Tumminello G., Maggioni A. P., Rapezzi C., Colombo A., Giannini F., Esposito A., Cereda, A, Toselli, M, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Mangieri, A, Khokhar, A, Campo, G, Scoccia, A, Bertini, M, Loffi, M, Sergio, P, Andreini, D, Pontone, G, Iannopollo, G, Nannini, T, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Vignali, L, Sverzellati, N, Iannaccone, M, Vaudano, P, Sangiorgi, G, Turchio, P, Monello, A, Tumminello, G, Maggioni, A, Rapezzi, C, Colombo, A, Giannini, F, Esposito, A, Cereda A., Toselli M., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Mangieri A., Khokhar A., Campo G., Scoccia A., Bertini M., Loffi M., Sergio P., Andreini D., Pontone G., Iannopollo G., Nannini T., Ippolito D., Bellani G., Patelli G., Besana F., Vignali L., Sverzellati N., Iannaccone M., Vaudano P. G., Sangiorgi G. M., Turchio P., Monello A., Tumminello G., Maggioni A. P., Rapezzi C., Colombo A., Giannini F., and Esposito A.
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Recent clinical and demographical studies on COVID-19 patients have demonstrated that men experience worse outcomes than women. However, in most cases, the data were not stratified according to gender, limiting the understanding of the real impact of gender on outcomes. This study aimed to evaluate the disaggregated in-hospital outcomes and explore the possible interactions between gender and cardiovascular calcifications. Data was derived from the sCORE-COVID-19 registry, an Italian multicentre registry that enrolled COVID-19 patients who had undergone a chest computer tomography scan on admission. A total of 1683 hospitalized patients (mean age 67±14 years) were included. Men had a higher prevalence of cardiovascular comorbidities, a higher pneumonia extension, more coronary calcifications (63% vs.50.9%, p<0.001), and a higher coronary calcium score (391±847 vs. 171±479 mm3, p<0.001). Men experienced a significantly higher mortality rate (24.4% vs. 17%, p=0.001), but the death event tended to occur earlier in women (15±7 vs. 8±7 days, p= 0.07). Non-survivors had a higher coronary, thoracic aorta, and aortic valve calcium score. Female sex, a known independent predictor of a favorable outcome in SARS-CoV2 infection, was not protective in women with a coronary calcification volume greater than 100 mm3. There were significant differences in cardiovascular comorbidities and vascular calcifications between men and women with SARS-CoV2 pneumonia. The differences in outcomes can be at least partially explained by the different cardiovascular profiles. However, women with poor outcomes had the same coronary calcific burden as men. The presumed favorable female sex bias in COVID-19 must therefore be reviewed in the context of comorbidities, especially cardiovascular ones.
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- 2021
35. Impact of clinical and subclinical coronary artery disease as assessed by coronary artery calcium in COVID-19
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Scoccia, A, Gallone, G, Cereda, A, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Monello, A, Khokhar, A, Sticchi, A, Biagi, A, Tacchetti, C, Campo, G, Rapezzi, C, Ponticelli, F, Danzi, G, Loffi, M, Pontone, G, Andreini, D, Casella, G, Iannopollo, G, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Costa, C, Vignali, L, Benatti, G, Iannaccone, M, Vaudano, P, Pacielli, A, De Carlini, C, Maggiolini, S, Bonaffini, P, Senni, M, Scarnecchia, E, Anastasio, F, Colombo, A, Ferrari, R, Esposito, A, Giannini, F, Toselli, M, Scoccia A., Gallone G., Cereda A., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Monello A., Khokhar A., Sticchi A., Biagi A., Tacchetti C., Campo G., Rapezzi C., Ponticelli F., Danzi G. B., Loffi M., Pontone G., Andreini D., Casella G., Iannopollo G., Ippolito D., Bellani G., Patelli G., Besana F., Costa C., Vignali L., Benatti G., Iannaccone M., Vaudano P. G., Pacielli A., De Carlini C. C., Maggiolini S., Bonaffini P. A., Senni M., Scarnecchia E., Anastasio F., Colombo A., Ferrari R., Esposito A., Giannini F., Toselli M., Scoccia, A, Gallone, G, Cereda, A, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Monello, A, Khokhar, A, Sticchi, A, Biagi, A, Tacchetti, C, Campo, G, Rapezzi, C, Ponticelli, F, Danzi, G, Loffi, M, Pontone, G, Andreini, D, Casella, G, Iannopollo, G, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Costa, C, Vignali, L, Benatti, G, Iannaccone, M, Vaudano, P, Pacielli, A, De Carlini, C, Maggiolini, S, Bonaffini, P, Senni, M, Scarnecchia, E, Anastasio, F, Colombo, A, Ferrari, R, Esposito, A, Giannini, F, Toselli, M, Scoccia A., Gallone G., Cereda A., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Monello A., Khokhar A., Sticchi A., Biagi A., Tacchetti C., Campo G., Rapezzi C., Ponticelli F., Danzi G. B., Loffi M., Pontone G., Andreini D., Casella G., Iannopollo G., Ippolito D., Bellani G., Patelli G., Besana F., Costa C., Vignali L., Benatti G., Iannaccone M., Vaudano P. G., Pacielli A., De Carlini C. C., Maggiolini S., Bonaffini P. A., Senni M., Scarnecchia E., Anastasio F., Colombo A., Ferrari R., Esposito A., Giannini F., and Toselli M.
- Abstract
Background and aims: The potential impact of coronary atherosclerosis, as detected by coronary artery calcium, on clinical outcomes in COVID-19 patients remains unsettled. We aimed to evaluate the prognostic impact of clinical and subclinical coronary artery disease (CAD), as assessed by coronary artery calcium score (CAC), in a large, unselected population of hospitalized COVID-19 patients undergoing non-gated chest computed tomography (CT) for clinical practice. Methods: SARS-CoV 2 positive patients from the multicenter (16 Italian hospitals), retrospective observational SCORE COVID-19 (calcium score for COVID-19 Risk Evaluation) registry were stratified in three groups: (a) “clinical CAD” (prior revascularization history), (b) “subclinical CAD” (CAC >0), (c) “No CAD” (CAC = 0). Primary endpoint was in-hospital mortality and the secondary endpoint was a composite of myocardial infarction and cerebrovascular accident (MI/CVA). Results: Amongst 1625 patients (male 67.2%, median age 69 [interquartile range 58–77] years), 31%, 57.8% and 11.1% had no, subclinical and clinical CAD, respectively. Increasing rates of in-hospital mortality (11.3% vs. 27.3% vs. 39.8%, p < 0.001) and MI/CVA events (2.3% vs. 3.8% vs. 11.9%, p < 0.001) were observed for patients with no CAD vs. subclinical CAD vs clinical CAD, respectively. The association with in-hospital mortality was independent of in-study outcome predictors (age, peripheral artery disease, active cancer, hemoglobin, C-reactive protein, LDH, aerated lung volume): subclinical CAD vs. No CAD: adjusted hazard ratio (adj-HR) 2.86 (95% confidence interval [CI] 1.14–7.17, p=0.025); clinical CAD vs. No CAD: adj-HR 3.74 (95% CI 1.21–11.60, p=0.022). Among patients with subclinical CAD, increasing CAC burden was associated with higher rates of in-hospital mortality (20.5% vs. 27.9% vs. 38.7% for patients with CAC score thresholds≤100, 101–400 and > 400, respectively, p < 0.001). The adj-HR per 50 points increase in C
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- 2021
36. Feasibility of late gadolinium enhancement (LGE) in ischemic cardiomyopathy using 2D-multisegment LGE combined with artificial intelligence reconstruction deep learning noise reduction algorithm
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Muscogiuri, G, Martini, C, Gatti, M, Dell'Aversana, S, Ricci, F, Guglielmo, M, Baggiano, A, Fusini, L, Bracciani, A, Scafuri, S, Andreini, D, Mushtaq, S, Conte, E, Gripari, P, Annoni, A, Formenti, A, Mancini, M, Bonfanti, L, Guaricci, A, Janich, M, Rabbat, M, Pompilio, G, Pepi, M, Pontone, G, Muscogiuri G., Martini C., Gatti M., Dell'Aversana S., Ricci F., Guglielmo M., Baggiano A., Fusini L., Bracciani A., Scafuri S., Andreini D., Mushtaq S., Conte E., Gripari P., Annoni A. D., Formenti A., Mancini M. E., Bonfanti L., Guaricci A. I., Janich M. A., Rabbat M. G., Pompilio G., Pepi M., Pontone G., Muscogiuri, G, Martini, C, Gatti, M, Dell'Aversana, S, Ricci, F, Guglielmo, M, Baggiano, A, Fusini, L, Bracciani, A, Scafuri, S, Andreini, D, Mushtaq, S, Conte, E, Gripari, P, Annoni, A, Formenti, A, Mancini, M, Bonfanti, L, Guaricci, A, Janich, M, Rabbat, M, Pompilio, G, Pepi, M, Pontone, G, Muscogiuri G., Martini C., Gatti M., Dell'Aversana S., Ricci F., Guglielmo M., Baggiano A., Fusini L., Bracciani A., Scafuri S., Andreini D., Mushtaq S., Conte E., Gripari P., Annoni A. D., Formenti A., Mancini M. E., Bonfanti L., Guaricci A. I., Janich M. A., Rabbat M. G., Pompilio G., Pepi M., and Pontone G.
- Abstract
Background: Despite the low spatial resolution of 2D-multisegment late gadolinium enhancement (2D-MSLGE) sequences, it may be useful in uncooperative patients instead of standard 2D single segmented inversion recovery gradient echo late gadolinium enhancement sequences (2D-SSLGE). The aim of the study is to assess the feasibility and comparison of 2D-MSLGE reconstructed with artificial intelligence reconstruction deep learning noise reduction (NR) algorithm compared to standard 2D-SSLGE in consecutive patients with ischemic cardiomyopathy (ICM). Methods: Fifty-seven patients with known ICM referred for a clinically indicated CMR were enrolled in this study. 2D-MSLGE were reconstructed using a growing level of NR (0%,25%,50%,75%and 100%). Subjective image quality, signal to noise ratio (SNR) and contrast to noise ratio (CNR) were evaluated in each dataset and compared to standard 2D-SSLGE. Moreover, diagnostic accuracy, LGE mass and scan time were compared between 2D-MSLGE with NR and 2D-SSLGE. Results: The application of NR reconstruction ≥50% to 2D-MSLGE provided better subjective image quality, CNR and SNR compared to 2D-SSLGE (p < 0.01). The best compromise in terms of subjective and objective image quality was observed for values of 2D-MSLGE 75%, while no differences were found in terms of LGE quantification between 2D-MSLGE versus 2D-SSLGE, regardless the NR applied. The sensitivity, specificity, negative predictive value, positive predictive value and accuracy of 2D-MSLGE NR 75% were 87.77%,96.27%,96.13%,88.16% and 94.22%, respectively. Time of acquisition of 2D-MSLGE was significantly shorter compared to 2D-SSLGE (p < 0.01). Conclusion: When compared to standard 2D-SSLGE, the application of NR reconstruction to 2D-MSLGE provides superior image quality with similar diagnostic accuracy.
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- 2021
37. Cardiac care of non-covid-19 patients during the sars-cov-2 pandemic: The pivotal role of ccta
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Conte, E, Mushtaq, S, Mancini, M, Annoni, A, Formenti, A, Muscogiuri, G, Asinelli, M, Gigante, C, Collet, C, Sonck, J, Guglielmo, M, Baggiano, A, Cosentino, N, Denora, M, Belmonte, M, Agalbato, C, Esposito, A, Assanelli, E, Bartorelli, A, Pepi, M, Pontone, G, Andreini, D, Conte E., Mushtaq S., Mancini M. E., Annoni A., Formenti A., Muscogiuri G., Asinelli M. G., Gigante C., Collet C., Sonck J., Guglielmo M., Baggiano A., Cosentino N., Denora M., Belmonte M., Agalbato C., Esposito A. A., Assanelli E., Bartorelli A. L., Pepi M., Pontone G., Andreini D., Conte, E, Mushtaq, S, Mancini, M, Annoni, A, Formenti, A, Muscogiuri, G, Asinelli, M, Gigante, C, Collet, C, Sonck, J, Guglielmo, M, Baggiano, A, Cosentino, N, Denora, M, Belmonte, M, Agalbato, C, Esposito, A, Assanelli, E, Bartorelli, A, Pepi, M, Pontone, G, Andreini, D, Conte E., Mushtaq S., Mancini M. E., Annoni A., Formenti A., Muscogiuri G., Asinelli M. G., Gigante C., Collet C., Sonck J., Guglielmo M., Baggiano A., Cosentino N., Denora M., Belmonte M., Agalbato C., Esposito A. A., Assanelli E., Bartorelli A. L., Pepi M., Pontone G., and Andreini D.
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Aim: The aim of this study is to evaluate the potential use of coronary CT angiography (CCTA) as the sole available non-invasive diagnostic technique for suspected coronary artery disease (CAD) during the coronavirus disease 2019 (COVID-19) pandemic causing limited access to the hospital facilities. Methods and Results: A consecutive cohort of patients with suspected stable CAD and clinical indication to non-invasive test was enrolled in a hub hospital in Milan, Italy, from March 9 to April 30, 2020. Outcome measures were obtained as follows: cardiac death, ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina. All the changes in medical therapy following the result of CCTA were annotated. A total of 58 patients with a mean age of 64 ± 11 years (36 men and 22 women) were enrolled. CCTA showed no CAD in 14 patients (24.1%), non-obstructive CAD in 30 (51.7%) patients, and obstructive CAD in 14 (24.1%) patients. Invasive coronary angiography (ICA) was considered deferrable in 48 (82.8%) patients. No clinical events were recorded after a mean follow-up of 376.4 ± 32.1 days. Changes in the medical therapy were significantly more prevalent in patients with vs. those without CAD at CCTA. Conclusion: The results of the study confirm the capability of CCTA to safely defer ICA in the majority of symptomatic patients and to correctly identify those with critical coronary stenoses necessitating coronary revascularization. This characteristic could be really helpful especially when the hospital resources are limited
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- 2021
38. State of the art paper: Cardiovascular CT for planning ventricular tachycardia ablation procedures
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Conte, E, Mushtaq, S, Carbucicchio, C, Piperno, G, Catto, V, Mancini, M, Formenti, A, Annoni, A, Guglielmo, M, Baggiano, A, Muscogiuri, G, Belmonte, M, Cattani, F, Pontone, G, Jereczek-Fossa, B, Orecchia, R, Tondo, C, Andreini, D, Conte E, Mushtaq S, Carbucicchio C, Piperno G, Catto V, Mancini ME, Formenti A, Annoni A, Guglielmo M, Baggiano A, Muscogiuri G, Belmonte M, Cattani F, Pontone G, Jereczek-Fossa BA, Orecchia R, Tondo C, Andreini D., Conte, E, Mushtaq, S, Carbucicchio, C, Piperno, G, Catto, V, Mancini, M, Formenti, A, Annoni, A, Guglielmo, M, Baggiano, A, Muscogiuri, G, Belmonte, M, Cattani, F, Pontone, G, Jereczek-Fossa, B, Orecchia, R, Tondo, C, Andreini, D, Conte E, Mushtaq S, Carbucicchio C, Piperno G, Catto V, Mancini ME, Formenti A, Annoni A, Guglielmo M, Baggiano A, Muscogiuri G, Belmonte M, Cattani F, Pontone G, Jereczek-Fossa BA, Orecchia R, Tondo C, and Andreini D.
- Abstract
In the last 20 years coronary computed tomography angiography (CCTA) gained a pivotal role in the evaluation of patients with suspected coronary artery disease (CAD) as finally recognized by the ESC guidelines on stable CAD. Technological advances have progressively improved the temporal resolution of CT scanners, contemporary reducing acquisition time, radiation dose and contrast volume needed for the whole heart volume acquisition, further expanding the role of cardiac CT beyond coronary anatomy evaluation. Aim of the present review is to discuss use and benefit of cardiac CT for the planning and preparation of VT ablation.
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- 2021
39. CarDiac magnEtic Resonance for prophylactic Implantable-cardioVerter defibrillAtor ThErapy in Non-Ischaemic dilated CardioMyopathy: an international Registry
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Guaricci, A, Masci, P, Muscogiuri, G, Guglielmo, M, Baggiano, A, Fusini, L, Lorenzoni, V, Martini, C, Andreini, D, Pavon, A, Aquaro, G, Barison, A, Todiere, G, Rabbat, M, Tat, E, Raineri, C, Valentini, A, Varga-Szemes, A, Schoepf, U, De Cecco, C, Bogaert, J, Dobrovie, M, Symons, R, Focardi, M, Gismondi, A, Lozano-Torres, J, Rodriguez-Palomares, J, Lanzillo, C, Di Roma, M, Moro, C, Di Giovine, G, Margonato, D, De Lazzari, M, Perazzolo Marra, M, Nese, A, Casavecchia, G, Gravina, M, Marzo, F, Carigi, S, Pica, S, Lombardi, M, Censi, S, Squeri, A, Palumbo, A, Gaibazzi, N, Camastra, G, Sbarbati, S, Pedrotti, P, Masi, A, Carrabba, N, Pradella, S, Timpani, M, Cicala, G, Presicci, C, Puglisi, S, Sverzellati, N, Santobuono, V, Pepi, M, Schwitter, J, Pontone, G, Guaricci AI, Masci PG, Muscogiuri G, Guglielmo M, Baggiano A, Fusini L, Lorenzoni V, Martini C, Andreini D, Pavon AG, Aquaro GD, Barison A, Todiere G, Rabbat MG, Tat E, Raineri C, Valentini A, Varga-Szemes A, Schoepf UJ, De Cecco CN, Bogaert J, Dobrovie M, Symons R, Focardi M, Gismondi A, Lozano-Torres J, Rodriguez-Palomares JF, Lanzillo C, Di Roma M, Moro C, Di Giovine G, Margonato D, De Lazzari M, Perazzolo Marra M, Nese A, Casavecchia G, Gravina M, Marzo F, Carigi S, Pica S, Lombardi M, Censi S, Squeri A, Palumbo A, Gaibazzi N, Camastra G, Sbarbati S, Pedrotti P, Masi A, Carrabba N, Pradella S, Timpani M, Cicala G, Presicci C, Puglisi S, Sverzellati N, Santobuono VE, Pepi M, Schwitter J, Pontone G, Guaricci, A, Masci, P, Muscogiuri, G, Guglielmo, M, Baggiano, A, Fusini, L, Lorenzoni, V, Martini, C, Andreini, D, Pavon, A, Aquaro, G, Barison, A, Todiere, G, Rabbat, M, Tat, E, Raineri, C, Valentini, A, Varga-Szemes, A, Schoepf, U, De Cecco, C, Bogaert, J, Dobrovie, M, Symons, R, Focardi, M, Gismondi, A, Lozano-Torres, J, Rodriguez-Palomares, J, Lanzillo, C, Di Roma, M, Moro, C, Di Giovine, G, Margonato, D, De Lazzari, M, Perazzolo Marra, M, Nese, A, Casavecchia, G, Gravina, M, Marzo, F, Carigi, S, Pica, S, Lombardi, M, Censi, S, Squeri, A, Palumbo, A, Gaibazzi, N, Camastra, G, Sbarbati, S, Pedrotti, P, Masi, A, Carrabba, N, Pradella, S, Timpani, M, Cicala, G, Presicci, C, Puglisi, S, Sverzellati, N, Santobuono, V, Pepi, M, Schwitter, J, Pontone, G, Guaricci AI, Masci PG, Muscogiuri G, Guglielmo M, Baggiano A, Fusini L, Lorenzoni V, Martini C, Andreini D, Pavon AG, Aquaro GD, Barison A, Todiere G, Rabbat MG, Tat E, Raineri C, Valentini A, Varga-Szemes A, Schoepf UJ, De Cecco CN, Bogaert J, Dobrovie M, Symons R, Focardi M, Gismondi A, Lozano-Torres J, Rodriguez-Palomares JF, Lanzillo C, Di Roma M, Moro C, Di Giovine G, Margonato D, De Lazzari M, Perazzolo Marra M, Nese A, Casavecchia G, Gravina M, Marzo F, Carigi S, Pica S, Lombardi M, Censi S, Squeri A, Palumbo A, Gaibazzi N, Camastra G, Sbarbati S, Pedrotti P, Masi A, Carrabba N, Pradella S, Timpani M, Cicala G, Presicci C, Puglisi S, Sverzellati N, Santobuono VE, Pepi M, Schwitter J, and Pontone G
- Abstract
Aims: The aim of this registry was to evaluate the additional prognostic value of a composite cardiac magnetic resonance (CMR)-based risk score over standard-of-care (SOC) evaluation in a large cohort of consecutive unselected non-ischaemic cardiomyopathy (NICM) patients. Methods and results: In the DERIVATE registry (www.clinicaltrials.gov/registration: RCT#NCT03352648), 1000 (derivation cohort) and 508 (validation cohort) NICM patients with chronic heart failure (HF) and left ventricular ejection fraction [removed]3 segments with midwall fibrosis on late gadolinium enhancement (LGE) were the only independent predictors of all-cause mortality (HR: 1.036, 95% CI: 1.0117-1.056, P < 0.001 and HR: 2.077, 95% CI: 1.211-3.562, P = 0.008, respectively). For MAACE, the independent predictors were male gender, left ventricular end-diastolic volume index by CMR (CMR-LVEDVi), and >3 segments with midwall fibrosis on LGE (HR: 2.131, 95% CI: 1.231-3.690, P = 0.007; HR: 3.161, 95% CI: 1.750-5.709, P < 0.001; and HR: 1.693, 95% CI: 1.084-2.644, P = 0.021, respectively). A composite clinical and CMR-based risk score provided a net reclassification improvement of 63.7% (P < 0.001) for MAACE occurrence when added to the model based on SOC evaluation. These findings were confirmed in the validation cohort. Conclusion: In a large multicentre, multivendor cohort registry reflecting daily clinical practice in NICM work-up, a composite clinical and CMR-based risk score provides incremental prognostic value beyond SOC evaluation, which may have impact on the indication of implantable cardioverter-defibrillator implantation.
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- 2021
40. Quantitative Evaluation of COVID-19 Pneumonia Lung Extension by Specific Software and Correlation with Patient Clinical Outcome. Quantitative Evaluation of COVID-19 Pneumonia Lung Extension by Specific Software and Correlation with Patient Clinical Outcome
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Annoni, A, Conte, E, Mancini, M, Gigante, C, Agalbato, C, Formenti, A, Muscogiuri, G, Mushtaq, S, Guglielmo, M, Baggiano, A, Bonomi, A, Pepi, M, Pontone, G, Andreini, D, Annoni AD, Conte E, Mancini ME, Gigante C, Agalbato C, Formenti A, Muscogiuri G, Mushtaq S, Guglielmo M, Baggiano A, Bonomi A, Pepi M, Pontone G, Andreini D, Annoni, A, Conte, E, Mancini, M, Gigante, C, Agalbato, C, Formenti, A, Muscogiuri, G, Mushtaq, S, Guglielmo, M, Baggiano, A, Bonomi, A, Pepi, M, Pontone, G, Andreini, D, Annoni AD, Conte E, Mancini ME, Gigante C, Agalbato C, Formenti A, Muscogiuri G, Mushtaq S, Guglielmo M, Baggiano A, Bonomi A, Pepi M, Pontone G, and Andreini D
- Abstract
Lung infection named as COVID-19 is an infectious disease caused by the most recently discovered coronavirus 2 (SARS-CoV-2). CT (computed tomography) has been shown to have good sensitivity in comparison with RT-PCR, particularly in early stages. However, CT findings appear to not always be related to a certain clinical severity. The aim of this study is to evaluate a correlation between the percentage of lung parenchyma volume involved with COVID-19 infection (compared to the total lung volume) at baseline diagnosis and correlated to the patient’s clinical course (need for ventilator assistance and or death). All patients with suspected COVID-19 lung disease referred to our imaging department for Chest CT from 24 February to 6 April 2020were included in the study. Specific CT features were assessed including the amount of high attenuation areas (HAA) related to lung infection. HAA, defined as the percentage of lung parenchyma above a predefined threshold of −650 (HAA%, HAA/total lung volume), was automatically calculated using a dedicated segmentation software. Lung volumes and CT findings were correlated with patient’s clinical course. Logistic regressions were performed to assess the predictive value of clinical, inflammatory and CT parameters for the defined outcome. In the overall population we found an average infected lung volume of 31.4 ± 26.3% while in the subgroup of patients who needed ventilator assistance and who died as well as the patients who died without receiving ventilator assistance the volume of infected lung was significantly higher 41.4 ± 28.5 and 72.7 ± 36.2 (p < 0.001). In logistic regression analysis best predictors for ventilation and death were the presence of air bronchogram (p = 0.006), crazy paving (p = 0.007), peripheral distribution (p < 0.001), age (p = 0.002), fever at admission (p = 0.007), dyspnea (p = 0.002) and cardiovascular comorbidities (p < 0.001). In multivariable analysis, quantitative CT parameters and features
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- 2021
41. Role of computed tomography in COVID-19
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Pontone, G, Scafuri, S, Mancini, M, Agalbato, C, Guglielmo, M, Baggiano, A, Muscogiuri, G, Fusini, L, Andreini, D, Mushtaq, S, Conte, E, Annoni, A, Formenti, A, Gennari, A, Guaricci, A, Rabbat, M, Pompilio, G, Pepi, M, Rossi, A, Pontone G, Scafuri S, Mancini ME, Agalbato C, Guglielmo M, Baggiano A, Muscogiuri G, Fusini L, Andreini D, Mushtaq S, Conte E, Annoni A, Formenti A, Gennari AG, Guaricci AI, Rabbat MR, Pompilio G, Pepi M, Rossi A, Pontone, G, Scafuri, S, Mancini, M, Agalbato, C, Guglielmo, M, Baggiano, A, Muscogiuri, G, Fusini, L, Andreini, D, Mushtaq, S, Conte, E, Annoni, A, Formenti, A, Gennari, A, Guaricci, A, Rabbat, M, Pompilio, G, Pepi, M, Rossi, A, Pontone G, Scafuri S, Mancini ME, Agalbato C, Guglielmo M, Baggiano A, Muscogiuri G, Fusini L, Andreini D, Mushtaq S, Conte E, Annoni A, Formenti A, Gennari AG, Guaricci AI, Rabbat MR, Pompilio G, Pepi M, and Rossi A
- Abstract
Coronavirus disease 2019 (COVID-19) has become a rapid worldwide pandemic. While COVID-19 primarily manifests as an interstitial pneumonia and severe acute respiratory distress syndrome, severe involvement of other organs has been documented. In this article, we will review the role of non-contrast chest computed tomography in the diagnosis, follow-up and prognosis of patients affected by COVID-19 pneumonia with a detailed description of the imaging findings that may be encountered. Given that patients with COVID-19 may also suffer from coagulopathy, we will discuss the role of CT pulmonary angiography in the detection of acute pulmonary embolism. Finally, we will describe more advanced applications of CT in the differential diagnosis of myocardial injury with an emphasis on ruling out acute coronary syndrome and myocarditis.
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- 2021
42. T1 mapping and cardiac magnetic resonance feature tracking in mitral valve prolapse
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Guglielmo, M, Fusini, L, Muscogiuri, G, Baessato, F, Loffreno, A, Cavaliere, A, Rizzon, G, Baggiano, A, Rabbat, M, Muratori, M, Tamborini, G, Danza, L, Del Torto, A, Tonet, E, Viani, G, Mushtaq, S, Conte, E, Bonalumi, G, Gripari, P, Zanobini, M, Andreini, D, Alamanni, F, Pepi, M, Guaricci, A, Pontone, G, Guglielmo M, Fusini L, Muscogiuri G, Baessato F, Loffreno A, Cavaliere A, Rizzon G, Baggiano A, Rabbat MG, Muratori M, Tamborini G, Danza LML, Del Torto A, Tonet E, Viani G, Mushtaq S, Conte E, Bonalumi G, Gripari P, Zanobini M, Andreini D, Alamanni F, Pepi M, Guaricci AI, Pontone G, Guglielmo, M, Fusini, L, Muscogiuri, G, Baessato, F, Loffreno, A, Cavaliere, A, Rizzon, G, Baggiano, A, Rabbat, M, Muratori, M, Tamborini, G, Danza, L, Del Torto, A, Tonet, E, Viani, G, Mushtaq, S, Conte, E, Bonalumi, G, Gripari, P, Zanobini, M, Andreini, D, Alamanni, F, Pepi, M, Guaricci, A, Pontone, G, Guglielmo M, Fusini L, Muscogiuri G, Baessato F, Loffreno A, Cavaliere A, Rizzon G, Baggiano A, Rabbat MG, Muratori M, Tamborini G, Danza LML, Del Torto A, Tonet E, Viani G, Mushtaq S, Conte E, Bonalumi G, Gripari P, Zanobini M, Andreini D, Alamanni F, Pepi M, Guaricci AI, and Pontone G
- Abstract
Objectives: T1 mapping (T1-map) and cardiac magnetic resonance feature tracking (CMR-FT) techniques have been introduced for the early detection of interstitial myocardial fibrosis and deformation abnormalities. We sought to demonstrate that T1-map and CMR-FT may identify the presence of subclinical myocardial structural changes in patients with mitral valve prolapse (MVP). Methods: Consecutive MVP patients with moderate-to-severe mitral regurgitation and comparative matched healthy subjects were prospectively enrolled and underwent CMR-FT analysis to calculate 2D global and segmental circumferential (CS) and radial strain (RS) and T1-map to determine global and segmental native T1 (nT1) values. Results: Seventy-three MVP patients (mean age, 57 ± 13 years old; male, 76%; regurgitant volume, 57 ± 21 mL) and 42 matched control subjects (mean age, 56 ± 18 years; male, 74%) were included. MVP patients showed a lower global CS (− 16.3 ± 3.4% vs. − 17.8 ± 1.9%, p = 0.020) and longer global nT1 (1124.9 ± 97.7 ms vs. 1007.4 ± 26.1 ms, p < 0.001) as compared to controls. Moreover, MVP patients showed lower RS and CS in basal (21.6 ± 12.3% vs. 27.6 ± 8.9%, p = 0.008, and − 13.0 ± 6.7% vs. − 14.9 ± 4.1%, p = 0.013) and mid-inferolateral (20.6 ± 10.7% vs. 28.4 ± 8.7%, p < 0.001, and − 12.8 ± 6.3% vs. − 16.5 ± 4.0%, p < 0.001) walls as compared to other myocardial segments. Similarly, MVP patients showed longer nT1 values in basal (1080 ± 68 ms vs. 1043 ± 43 ms, p < 0.001) and mid-inferolateral (1080 ± 77 ms vs. 1034 ± 37 ms, p < 0.001) walls as compared to other myocardial segments. Of note, nT1 values were significantly correlated with CS (r, 0.36; p < 0.001) and RS (r, 0.37; p < 0.001) but not with regurgitant volume. Conclusions: T1-map and CMR-FT identify subclinical left ventricle tissue changes in patients with MVP. Further studies are required to correlate these subclinical tissue changes with the outcome. Key Points: • T1 mapping (T1-map) and cardia
- Published
- 2021
43. Assessment Of Surgical Revascularization Completeness With Quantitative Myocardial Blood Flow Distribution Derived From Ccta In Severe Coronary Artery Disease.
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Serruys, P., Tsai, T., Kageyama, S., Tanaka, K., De Mey, J., La Meir, M., Schneider, U., Doenst, T., Mushtaq, S., Pompilio, G., Andreini, D., Pontone, G., Puskas, J., Narula, J., and Onuma, Y.
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- 2024
- Full Text
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44. Early versus late acute coronary syndrome risk patterns of coronary atherosclerotic plaque
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Hoogen, I.J. van den, Stuijfzand, W.J., Gianni, U., Rosendael, A.R. van, Bax, A.M., Lu, Y., Tantawy, S.W., Hollenberg, E.J., Andreini, D., Al-Mallah, M.H., Cademartiri, F., Chinnaiyan, K., Chow, B.J.W., Conte, E., Cury, R.C., Feuchtner, G., Goncalves, P.D., Hadamitzky, M., Kim, Y.J., Leipsic, J., Maffei, E., Marques, H., Plank, F., Pontone, G., Villines, T.C., Lee, S.E., Al'Aref, S.J., Baskaran, L., Danad, I., Gransar, H., Budoff, M.J., Samady, H., Virmani, R., Berman, D.S., Chang, H.J., Narula, J., Min, J.K., Bax, J.J., Lin, F.Y., Shaw, L.J., ICONIC Investigators, Cardiology, and ACS - Atherosclerosis & ischemic syndromes
- Subjects
Male ,Computed Tomography Angiography ,Settore MED/11 - Malattie dell'Apparato Cardiovascolare ,General Medicine ,Middle Aged ,Coronary Angiography ,Plaque, Atherosclerotic ,acute coronary syndrome ,Cross-Sectional Studies ,Predictive Value of Tests ,Humans ,Female ,Radiology, Nuclear Medicine and imaging ,coronary computed tomography angiography ,atherosclerosis ,Cardiology and Cardiovascular Medicine ,coronary artery disease ,Aged - Abstract
Aims The temporal instability of coronary atherosclerotic plaque preceding an incident acute coronary syndrome (ACS) is not well defined. We sought to examine differences in the volume and composition of coronary atherosclerosis between patients experiencing an early (≤90 days) versus late ACS (>90 days) after baseline coronary computed tomography angiography (CCTA). Methods and results From a multicenter study, we enrolled patients who underwent a clinically indicated baseline CCTA and experienced ACS during follow-up. Separate core laboratories performed blinded adjudication of ACS events and quantification of CCTA including compositional plaque volumes by Hounsfield units (HU): calcified plaque >350 HU, fibrous plaque 131–350 HU, fibrofatty plaque 31–130 HU and necrotic core Conclusions Volumetric differences in composition of coronary atherosclerosis exist between ACS patients according to their timing antecedent to the acute event. These data support that a large burden of non-calcified plaque on CCTA is strongly associated with near-term plaque instability and ACS risk.
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- 2022
45. Feasibility study of a mixed reality tool for real 3D visualization and planning of left atrial appendage occlusion
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Pasquali, M., primary, Fusini, L., additional, Italiano, G., additional, Maltagliati, A., additional, Tamborini, G., additional, Penso, M., additional, Andreini, D., additional, Redaelli, A., additional, Pappalardo, O., additional, and Pepi, M., additional
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- 2022
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46. Phantom study of stereotactic radioablation for ventricular tachycardia (STRA-MI-VT) using Cyberknife Synchrony Respiratory Tracking System with a single fiducial marker
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Piccolo, C., primary, Vigorito, S., additional, Rondi, E., additional, Piperno, G., additional, Ferrari, A., additional, Pepa, M., additional, Riva, G., additional, Durante, S., additional, Conte, E., additional, Catto, V., additional, Andreini, D., additional, Carbucicchio, C., additional, Jereczek-Fossa, B.A., additional, Pompilio, G., additional, Orecchia, R., additional, and Cattani, F., additional
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- 2022
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47. 462 Comparison Of The Syntax Score 2020 Based On Coronary Artery Computed Tomography (CCTA) With Invasive Coronary Angiography (ICA)
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Masuda, S., primary, Kageyama, S., additional, Kotoku, N., additional, Ninomiya, K., additional, Schneider, U., additional, Doenst, T., additional, Tanaka, K., additional, Mey, J., additional, Meir, M., additional, Mushtaq, S., additional, Bartorelli, A., additional, Pompilio, G., additional, Andreini, D., additional, Onuma, Y., additional, and Serruys, P., additional
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- 2022
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48. 478 Pre-tavi Aortic Annulus Sizing: Comparison Between Manual And Semi-automated New Generation Software Measurements
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Annoni, A., primary, Andreini, D., additional, Mancini, M., additional, Mushtaq, S., additional, Formenti, A., additional, Baggiano, A., additional, Carlicchi, E., additional, Conte, E., additional, and Pontone, G., additional
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- 2022
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49. 437 Accuracy Of The FFRCTPlanner In Coronary Calcific Lesions
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Belmonte, M., primary, Collet, C., additional, Nørgaard, B., additional, Otake, H., additional, Koo, B., additional, Andreini, D., additional, Mizukami, T., additional, Updegrove, A., additional, Barbato, E., additional, De Bruyne, B., additional, Leipsic, J., additional, Taylor, C., additional, Maeng, M., additional, and Sonck, J., additional
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- 2022
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50. Quantitative versus qualitative evaluation of static stress computed tomographic perfusion to detect hemodinamically significant coronary artery disease in intermediate to high risk patients: P719
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Guglielmo, M., Guaricci, A I., Baggiano, A., Fazzari, F., Andreini, D., Calligaris, G., Galli, S., Teruzzi, G., Trabattoni, D., Fabbiocchi, F., Lualdi, A., Montorsi, P., Bartorelli, A., Pepi, M., and Pontone, G.
- Published
- 2017
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