65 results on '"Andreas, Eichhorn"'
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2. IMU/magnetometer based 3D indoor positioning for wheeled platforms in NLoS scenarios.
- Author
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Hendrik Hellmers, Andreas Eichhorn, Abdelmoumen Norrdine, and Jörg Blankenbach
- Published
- 2016
- Full Text
- View/download PDF
3. Auffinde- und Passagedauer als Parameter zur Funktionsbewertung von Fischaufstiegsanlagen
- Author
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Ulrich Schwevers, Sabrina Steineck, Boris Lehmann, and Andreas Eichhorn
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Water Science and Technology - Published
- 2022
4. Indoor localisation for wheeled platforms based on IMU and artificially generated magnetic field.
- Author
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Hendrik Hellmers, Andreas Eichhorn, Abdelmoumen Norrdine, and Jörg Blankenbach
- Published
- 2014
- Full Text
- View/download PDF
5. An IMU/magnetometer-based Indoor positioning system using Kalman filtering.
- Author
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Hendrik Hellmers, Abdelmoumen Norrdine, Jörg Blankenbach, and Andreas Eichhorn
- Published
- 2013
- Full Text
- View/download PDF
6. Zur musikalischen Interpretationsgeschichte von Kurt Weills Violinkonzert op. 12
- Author
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Andreas Eichhorn
- Subjects
Music - Abstract
Unter allen 25 untersuchten Aufnahmen ist Hermann Scherchen der einzige, der Kurt Weills Tempoarchitektur nicht nur korrekt, sondern auch mit großer Plastizität herausmodelliert. Als vorläufiges Resümee der Interpretationsgeschichte des ersten Satzes von Weills Violinkonzert ließe sich festhalten, dass die Entschlüsselung seines Aufführungssinns nicht nur disparat ausfällt, sondern dass das Werk seit Scherchen immer noch einer angemessenen Realisation seiner Tempoarchitektur harrt.
- Published
- 2021
7. Vom Volksfest zur 'musikalischen Prunkausstellung'
- Author
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Andreas Eichhorn
- Subjects
Music - Abstract
Die Musikfestlandschaft des 19. Jahrhunderts ist ausgesprochen vielfältig. Ihre Entwicklung steht im Kontext der jeweils unterschiedlichen lokalen Gegebenheiten, der politischen Situation und der Veränderung des allgemeinen Musiklebens. Artikulierte sich bis 1815 ein aktives, bürgerliches Bildungsinteresse vermischt mit nationalpatriotisch-freiheitlicher Gesinnung, so standen später politische Aspekte eher im Hintergund. Je stärker die von den Musikfesten auf das allgemeine Musikleben ausstrahlenden Impulse ihre belebende Wirkung entfalteten, desto mehr veränderten die Musikfeste ihr Profil: Sie wandelten sich zu professionellen Konzertveranstaltungen gehobenen Niveaus. Damit büßten sie ihren Volksfestcharakter ein. Einige monumentale Musikfeste sind als Zeichen des Fortschrittsenthusiasmus des industriellen Zeitalters zu sehen.
- Published
- 2021
8. 'Hauptthema' im ersten Satz von Beethovens Neunter Symphonie
- Author
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Andreas Eichhorn
- Subjects
Music - Abstract
Der expositionelle Gehalt des Hauptthemenkomplexes der Neunten Symphonie Beethovens erschöpft sich nicht allein im thematisch-motivischen Material. Exponiert werden zugleich auch bestimmte Texturmodelle, die sich satzübergreifend ausbreiten und zur Werkeinheit beitragen. Als traditionelle Substanz ist dem Hauptthemenkomplex der dorische Ton eingeschrieben. Indem Beethoven an dem einzelnen Strukturelementen entlangkomponiert, wird das Dorische zu einem strukturellen Gerüst, das die äußerlich heterogene Syntax verklammert.
- Published
- 2021
9. Tasks and newest trends in geodetic deformation analysis: A tutorial.
- Author
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Andreas Eichhorn
- Published
- 2007
10. WiKaF - A Knowledge-based Kalman-Filter for Pedestrian Positioning.
- Author
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Michael Thienelt, Andreas Eichhorn, and Alexander Reiterer
- Published
- 2007
- Full Text
- View/download PDF
11. Map-independent positioning of land vehicles with causative modified motion equations.
- Author
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Andreas Eichhorn
- Published
- 2007
- Full Text
- View/download PDF
12. Improved Classification of Surface Defects for Quality Control of Car Body Panels.
- Author
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Christian Döring, Andreas Eichhorn, Xiaomeng Wang, and Rudolf Kruse
- Published
- 2006
- Full Text
- View/download PDF
13. Neuro-fuzzy classification of surface form deviations.
- Author
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Andreas Eichhorn, Daniela Girimonte, Aljoscha Klose, and Rudolf Kruse
- Published
- 2003
- Full Text
- View/download PDF
14. Polyhedral Risk Measures and Lagrangian Relaxation in Electricity Portfolio Optimization.
- Author
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Andreas Eichhorn, Werner Römisch, and Isabel Wegner
- Published
- 2005
15. Felix Mendelssohn Bartholdy: Elias
- Author
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Andreas Eichhorn and Andreas Eichhorn
- Abstract
Mendelssohns'Elias'- das romantische Oratorium als herausragendes Werk der Musikgeschichte erläutert. Mendelssohns'Elias'ist neben dem'Paulus'eines der wenigen romantischen Oratorien, das auch heute aufgeführt wird und sich seit den 1970er-Jahren steigender Aufführungszahlen erfreut. Was den'Elias'so beliebt macht, ist die Modernität seiner Dramaturgie: Wem geht nicht die Spannung angesichts der heraufziehenden Regenwolke, die Erscheinung Gottes am Horeb oder die zunehmende Aggression des Volkes unter die Haut? Mit der weitgehenden Dramatisierung des Handlungsverlaufs realisiert Mendelssohn ein Oratorienkonzept, das damals zwar umstritten war, aber dem Oratorium eine überwältigende, fast opernhaft szenische Plastizität verleiht. Eichhorns Werkeinführung beleuchtet zunächst die Sonderstellung des'Elias'im gattungsgeschichtlichen Kontext, erläutert die Entstehungsgeschichte und profiliert das Werk als Ganzes. Im Hauptteil werden die einzelnen Nummern in allgemein verständlicher Sprache prägnant und anschaulich erläutert. Ausblicke auf die wechselvolle Rezeptionsgeschichte runden die Werkmonographie ab. Die mit Notenbeispielen ausgestattete Werkeinführung eignet sich für Chorsänger, musikinteressierte Laien, Konzertbesucher und Musikstudenten. Felix Mendelssohn Bartholdy realisierte mit seinem großen Oratorium'Elias'ein Konzept, das in seiner Zeit für Diskussionen sorgte und heute einer der Gründe für seine Beliebtheit ist: Er dramatisierte den Handlungsverlauf und gestaltete die Abschnitte zu fast opernhaften Szenen, die bis heute sowohl Chorsänger als auch Zuhörer gefangen nehmen. Andreas Eichhorn hat seine Werkeinführung so angelegt, dass die einzelnen Kapitel unabhängig voneinander gelesen werden können. Dadurch erhält der Leser einen schnellen Überblick, findet aber auch spezielle Informationen zu einzelnen Sätzen des Werkes. Das Buch umfasst neben einer kurzen Einführung in die Geschichte des Oratoriums im 19. Jahrhundert und dem kompletten Libretto die folgenden Kapitel: Entstehungsgeschichte / Werkgestalt / Szenisch-dramaturgisches Konzept / Musikalische Gestaltung / Aspekte der Rezeption
- Published
- 2019
16. Belastungsversuche an einer Mauerwerksbrücke: Terrestrisches Laserscanning zur Verformungsmessung
- Author
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Mathias Burger, Ralf Lichtenberger, Ingo Neumann, Ulrich Stenz, Frank Neitzel, Jens-André Paffenholz, Andreas Eichhorn, Daniel Wujanz, and Florian Schill
- Subjects
010504 meteorology & atmospheric sciences ,0211 other engineering and technologies ,02 engineering and technology ,01 natural sciences ,021101 geological & geomatics engineering ,0105 earth and related environmental sciences - Abstract
Dieser Beitrag fokussiert auf die Uberwachung einer historischen Brucke mittels terrestrischem Laserscanning wahrend eines Belastungsversuchs. Dabei wurde ein Belastungsregime von etwa 1 bis 6 MN durchfahren. Zur Erfassung der statischen Haltephasen wurden 3-D-Laserscanner eingesetzt, welche die Verformung der Brucke infolge des Lasteintrags dokumentieren. Um Verfalschungen der zu berechnenden Verformungen ausschliesen zu konnen, wurde zum einen eine ebenenbasierte Registrierung basierend auf stabilen Objektbereichen und zum anderen eine Referenzierung uber diskrete, signalisierte Stabilpunkte durchgefuhrt. Mit dem Einsatz eines Profillaserscanners konnte zusatzlich zum statischen auch der dynamische Lasteintrag uberwacht werden. Im Rahmen dieses Beitrags wurde dazu das Konzept der Klassenreprasentanten eingesetzt. Das hier gezeigte Rauschniveau lag dabei im Bereich von 0,1 mm und kann somit auch kleinmasstabliche geometrische Veranderungen infolge der Auflast nachweisen.
- Published
- 2018
17. Accurate 3D Positioning for a Mobile Platform in Non-Line-of-Sight Scenarios Based on IMU/Magnetometer Sensor Fusion
- Author
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Zakaria Kasmi, Abdelmoumen Norrdine, Andreas Eichhorn, and Hendrik Hellmers
- Subjects
robotic ,Computer science ,mobile platform ,Real-time computing ,MILPS ,Ultra-wideband ,magnetic field ,02 engineering and technology ,indoor positioning ,Kalman filter ,magnetometer ,pressure sensor ,barometer ,01 natural sciences ,Biochemistry ,Article ,Analytical Chemistry ,Non-line-of-sight propagation ,Indoor positioning system ,Inertial measurement unit ,0202 electrical engineering, electronic engineering, information engineering ,Computer Science::Networking and Internet Architecture ,Fading ,Electrical and Electronic Engineering ,Instrumentation ,020208 electrical & electronic engineering ,010401 analytical chemistry ,Sensor fusion ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,GNSS applications ,Ultrasonic sensor ,Multipath propagation - Abstract
In recent years, a variety of real-time applications benefit from services provided by localization systems due to the advent of sensing and communication technologies. Since the Global Navigation Satellite System (GNSS) enables localization only outside buildings, applications for indoor positioning and navigation use alternative technologies. Ultra Wide Band Signals (UWB), Wireless Local Area Network (WLAN), ultrasonic or infrared are common examples. However, these technologies suffer from fading and multipath effects caused by objects and materials in the building. In contrast, magnetic fields are able to pass through obstacles without significant propagation errors, i.e. in Non-Line of Sight Scenarios (NLoS). The aim of this work is to propose a novel indoor positioning system based on artificially generated magnetic fields in combination with Inertial Measurement Units (IMUs). In order to reach a better coverage, multiple coils are used as reference points. A basic algorithm for three-dimensional applications is demonstrated as well as evaluated in this article. The established system is then realized by a sensor fusion principle as well as a kinematic motion model on the basis of a Kalman filter. Furthermore, a pressure sensor is used in combination with an adaptive filtering method to reliably estimate the platform’s altitude. View Full-Text
- Published
- 2018
- Full Text
- View/download PDF
18. IMU/magnetometer based 3D indoor positioning for wheeled platforms in NLoS scenarios
- Author
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Andreas Eichhorn, Jörg Blankenbach, Hendrik Hellmers, and Abdelmoumen Norrdine
- Subjects
0209 industrial biotechnology ,Orientation (computer vision) ,Computer science ,Magnetometer ,020208 electrical & electronic engineering ,02 engineering and technology ,law.invention ,Non-line-of-sight propagation ,020901 industrial engineering & automation ,Inertial measurement unit ,law ,0202 electrical engineering, electronic engineering, information engineering ,Electronic engineering ,Fading ,Ultrasonic sensor ,Multipath propagation - Abstract
In recent years the research on localization and navigation systems in GNSS-denied environments has been focused from both industry and research. Although many technologies based on e.g. UWB, WLAN, ultrasonic or infrared have been utilized, there is still no final solution for position and orientation determination in indoor areas. The fact, that applied signals in common approaches are influenced by fading and multipath inside buildings leads to restrictions on line-of-sight (LoS) conditions.
- Published
- 2016
19. Medikamentöse Versorgung des Behçet-Syndroms mit Chlorambucil
- Author
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Andreas Eichhorn, Wilhelm Kirch, and Martin Siepmann
- Subjects
Erythema nodosum ,medicine.medical_specialty ,Chlorambucil ,business.industry ,Incidence (epidemiology) ,General Medicine ,medicine.disease ,Dermatology ,stomatognathic diseases ,Oral administration ,Prednisone ,Rheumatoid arthritis ,Medicine ,Methotrexate ,business ,medicine.drug ,Systemic vasculitis - Abstract
Background: Behcet's syndrome rarely occurs in North America and Central Europe (incidence: 1: 500,000), whereas it is more frequently seen in Japan and Mediterranean countries (incidence: 1: 10,000). The diagnosis is based on the detection of symptoms and clinical signs. Orogenital aphthosis, anterior and posterior uveitides that frequently cause loss of vision are considered to be primary symptoms. Dermatologic manifestations, i.e., erythema nodosum, vascular lesions (angio-Behcet's syndrome), gastrointestinal ulcers and neurologic involvement, can be observed. HLA B5 is found in some of the patients with Behcet's syndrome. Administration of chlorambucil, a cytotoxic compound, is an effective form of treatment of symptoms and complications of Behcet's syndrome. Case Reports: The present article describes the course of a female and a male patient who were 39 and 23 years old when Behcet's syndrome was diagnosed for the first time. Treatment whith chlorambucil was started in the early 1990s and continued for a period of 9½ and 3 3/4 years, respectively, with the symptoms remitting during and after this therapy. Approximately 10 years after the start of treatment with chlorambucil, the patients' symptoms changed. The female patient who was first diagnosed having Behcet's syndrome at the age of 39 years developed rheumatoid arthritis with joint destruction. Her symptoms could be controlled in the long term by oral administration of prednisone, at doses below the Cushing threshold combined with methotrexate. The male patient who was first diagnosed having Behcet's syndrome at the age of 23 years developed systemic vasculitis remitting during low-dose treatment with prednisone. Conclusion: Immunosuppressive therapy with chlorambucil administered over several years often induces remission of Behcet's syndrome. However, both case reports indicate that symptoms can change from Behcet's syndrome to systemic vasculitis or rheumatoid arthritis.
- Published
- 2010
20. Innenhochdruckabschneiden von Hohlprofilen
- Author
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Andreas Eichhorn, Bernhard Karpuschewski, and Walter Tóth
- Subjects
Strategy and Management ,General Engineering ,Management Science and Operations Research - Abstract
Kurzfassung In den letzten Jahren konnte die Herstellung eigenschaftsoptimierter Bauteile, besonders im Hinblick auf geringes Gewicht und hohe Funktionalität, durch die Anwendung von Innenhochdruckumformtechnologien in der industriellen Praxis auf ein beachtliches Niveau gebracht werden. Die Realisierung des Innenhochdruckumformens erfordert in der Regel eine lange Prozesskette mit vor- und nachgelagerten Prozessschritten. Das Innenhochdruckabschneiden bietet die Möglichkeit, bislang in separaten Prozessstufen durchgeführte Schneidoperationen in den Innenhochdruckumformprozess zu integrieren und somit die Effektivität des Gesamtprozesses zu erhöhen. Im vorliegenden Artikel werden wesentliche Ergebnisse der wissenschaftlichen Untersuchungen zum Innenhochdruckabschneiden mit Schneidring unter inhomogenen Schneidbedingungen für innenhochdruckumgeformte Hohlprofile mit Quadrat- und Rechteckquerschnitt dargestellt.
- Published
- 2008
21. Stability of multistage stochastic programs incorporating polyhedral risk measures
- Author
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Andreas Eichhorn and Werner Römisch
- Subjects
Mathematical optimization ,Continuous-time stochastic process ,Control and Optimization ,Basis (linear algebra) ,Process (engineering) ,Stochastic process ,Applied Mathematics ,Bounded function ,Filtration (mathematics) ,Stability (learning theory) ,Sensitivity (control systems) ,Management Science and Operations Research ,Mathematics - Abstract
We analyse stability aspects of linear multistage stochastic programs with polyhedral risk measures in the objective. In particular, we consider sensitivity of the optimal value with respect to perturbations of the underlying stochastic input process. An existing stability result for multistage stochastic programs with expectation objective is carried forward to the case of polyhedral risk-averse objectives. Beside Lr-distances these results also involve filtration distances of the perturbations of the stochastic process. We discuss additional requirements for the polyhedral risk measures such that the problem dependent filtration distances can be bounded by problem independent ones. Stability and such bounds are the basis for scenario tree approximation techniques used in practical problem solving.
- Published
- 2008
22. Klang und Eros. Gesammelte Schriften Bd. 2
- Author
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Paul Bekker (Au), Herbert Schneider (Ed), Andreas Eichhorn (Ed), Paul Bekker (Au), Herbert Schneider (Ed), and Andreas Eichhorn (Ed)
- Abstract
Paul Bekker (1882-1937) war zwischen 1910 und 1925 der einflussreichste deutschsprachige Musikpublizist. Die sprachliche Brillanz seiner Texte, die Plastizität und Unkonventionalität seiner Thesen erschlossen sich einen Leserkreis, der weit über das engere musikalische Fachpublikum hinausging. Bekkers publizistische Aktivitäten fallen in eine Zeit, die sich als gravierende kulturelle Umbruchsphase des frühen 20. Jahrhunderts darstellt. Theodor W. Adorno bezeichnete ihn als den gescheitesten Musikkritiker in Deutschland zwischen den beiden Kriegen. Bekker prägte während seiner Tätigkeit an der Frankfurter Zeitung (1911–1924) maßgeblich das Berufsbild des professionellen Musikkritikers, und er setzte sich nicht nur emphatisch für die neue Musik – für Mahler, Hindemith, Krenek, Schönberg, Schreker ein, sondern stellte als Publizist, enger Berater Kestenbergs und Intendant zweier Preußischer Staatstheater (Kassel, Wiesbaden) seine ganze Persönlichkeit in den Dienst des Aufbaus moderner, demokratischer Strukturen für die Kultur. Bekker war eine zentrale Figur im Musikleben der Weimarer Republik. Nach seiner Entlassung aufgrund der jüdischen Herkunft im Jahre 1933 emigrierte er in die USA. Geistig fühlte er sich zeitlebens dem ethisch-humanitären Gedankengut der Aufklärung verbunden. Die Texte in'Klang und Eros'stehen außerhalb des Kreises tagesaktueller kulturpolitischer Kontroversen. Es ist kein Zufall, dass Bekker den Titel des abschließenden Aufsatz „Klang und Eros“ als Buchtitel gewählt hat und seinen Lesern empfiehlt, diesen zuerst zu lesen. Darin geht er vom „Klang“ aus: „Von fernher klingt der Gesang einer Frauenstimme. Ein seltsamer, schwerer Duft strömt aus ihr. Was ist das? Der Reiz der Melodie kann es nicht sein, wenn ich sie für mich wiederhole, ist der eigentliche Zauber entwichen. Auch der Klang als physikalisches Phänomen erklärt die Wirkung nicht, denn die nachspielende Violine gibt sofort einen veränderten Eindruck. Es muß etwas anderes sein, etwas, dem gegenüber die akustische Klangerscheinung und das ästhetische Wohlgefallen an der Melodie nebengeordnete Begleitwirkungen sind. Mir scheint, es ist die Stimme an sich […].“ Bekker entwickelt eine Phänomenologie des Klanges auf der Basis seiner Materialität, die unabhängig von künstlerischer Formung, von geistigen, ästhetischen oder historischen Bedingtheiten ist. Er knüpft den Klang an das Medium seiner Erzeugung.
- Published
- 2014
23. Neue Musik. Gesammelte Schriften Bd. 3
- Author
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Paul Bekker (Au), Herbert Schneider (Ed), Andreas Eichhorn (Ed), Paul Bekker (Au), Herbert Schneider (Ed), and Andreas Eichhorn (Ed)
- Abstract
Paul Bekker (1882-1937) war zwischen 1910 und 1925 der einflussreichste deutschsprachige Musikpublizist. Die sprachliche Brillanz seiner Texte, die Plastizität und Unkonventionalität seiner Thesen erschlossen sich einen Leserkreis, der weit über das engere musikalische Fachpublikum hinausging. Bekkers publizistische Aktivitäten fallen in eine Zeit, die sich als gravierende kulturelle Umbruchsphase des frühen 20. Jahrhunderts darstellt. Theodor W. Adorno bezeichnete ihn als den gescheitesten Musikkritiker in Deutschland zwischen den beiden Kriegen. Bekker prägte während seiner Tätigkeit an der Frankfurter Zeitung (1911–1924) maßgeblich das Berufsbild des professionellen Musikkritikers, und er setzte sich nicht nur emphatisch für die neue Musik – für Mahler, Hindemith, Krenek, Schönberg, Schreker ein, sondern stellte als Publizist, enger Berater Kestenbergs und Intendant zweier Preußischer Staatstheater (Kassel, Wiesbaden) seine ganze Persönlichkeit in den Dienst des Aufbaus moderner, demokratischer Strukturen für die Kultur. Bekker war eine zentrale Figur im Musikleben der Weimarer Republik. Nach seiner Entlassung aufgrund der jüdischen Herkunft im Jahre 1933 emigrierte er in die USA. Geistig fühlte er sich zeitlebens dem ethisch-humanitären Gedankengut der Aufklärung verbunden. Für seine Schriftensammlung'Neue Musik'hat Bekker einen thematischen Kern benannt, nämlich die Auseinandersetzung mit der Romantik. Unter den Aufsätzen des Bandes war der Essay „Die Sinfonie von Beethoven bis Mahler“ (1918) der folgenreichste. Bekker ging es dabei nicht um einen historischen Überblick, sondern sein Ziel war es, das „Wesen der sinfonischen Gattung“ zu bestimmen. Bekkers These von der „gesellschaftsbildenden“ Kraft der Beethovenschen Sinfonik wurde vielfältig rezipiert, auch kritisch. Sie wirkte beispielsweise bei Adorno nach wie auch bei Carl Dahlhaus.
- Published
- 2014
24. Kritische Zeitbilder. Gesammelte Schriften Bd. 1
- Author
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Paul Bekker (Au), Herbert Schneider (Ed), Andreas Eichhorn (Ed), Paul Bekker (Au), Herbert Schneider (Ed), and Andreas Eichhorn (Ed)
- Abstract
Paul Bekker (1882-1937) war zwischen 1910 und 1925 der einflussreichste deutschsprachige Musikpublizist. Die sprachliche Brillanz seiner Texte, die Plastizität und Unkonventionalität seiner Thesen erschlossen sich einen Leserkreis, der weit über das engere musikalische Fachpublikum hinausging. Bekkers publizistische Aktivitäten fallen in eine Zeit, die sich als gravierende kulturelle Umbruchsphase des frühen 20. Jahrhunderts darstellt. Theodor W. Adorno bezeichnete ihn als den gescheitesten Musikkritiker in Deutschland zwischen den beiden Kriegen. Bekker prägte während seiner Tätigkeit an der Frankfurter Zeitung (1911–1924) maßgeblich das Berufsbild des professionellen Musikkritikers, und er setzte sich nicht nur emphatisch für die neue Musik – für Mahler, Hindemith, Krenek, Schönberg, Schreker ein, sondern stellte als Publizist, enger Berater Kestenbergs und Intendant zweier Preußischer Staatstheater (Kassel, Wiesbaden) seine ganze Persönlichkeit in den Dienst des Aufbaus moderner, demokratischer Strukturen für die Kultur. Bekker war eine zentrale Figur im Musikleben der Weimarer Republik. Nach seiner Entlassung aufgrund der jüdischen Herkunft im Jahre 1933 emigrierte er in die USA. Geistig fühlte er sich zeitlebens dem ethisch-humanitären Gedankengut der Aufklärung verbunden. Der Band ist in drei große Kapitel aufgeteilt: Das „erste bringt Charakteristiken von Persönlichkeiten und Werken“, das „zweite zeitgeschichtliche Betrachtungen“, das „dritte ästhetische Auseinandersetzungen. Zusammengefasst umschließen sie das gesamte Gebiet, das dem Kritiker der Tageszeitung zur Verfügung steht.“ Zweifellos bilden die Beiträge, die im Kontext der Auseinandersetzung mit Hans Pfitzner entstanden sind – darunter vor allem der bereits 1917 „im Felde“ geschriebene Aufsatz „Erfinder und Gestalter“, der Pfitzner zu seiner Schrift Die neue Ästhetik der musikalischen Impotenz. Ein Verwesungssymptom? provozierte – das Zentrum dieses Bands.
- Published
- 2014
25. Stochastic Integer Programming: Limit Theorems and Confidence Intervals
- Author
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Werner Römisch and Andreas Eichhorn
- Subjects
Discrete mathematics ,Delta method ,General Mathematics ,Resampling ,Limit (mathematics) ,Management Science and Operations Research ,Stability (probability) ,Stochastic programming ,Empirical process ,Confidence interval ,Computer Science Applications ,Central limit theorem ,Mathematics - Abstract
We consider empirical approximations (sample average approximations) of two-stage stochastic mixed-integer linear programs and derive central limit theorems for the objectives and optimal values. The limit theorems are based on empirical process theory and the functional delta method. We also show how these limit theorems can be used to derive confidence intervals for optimal values via resampling methods (bootstrap, subsampling).
- Published
- 2007
26. Soft computing for automated surface quality analysis of exterior car body panels
- Author
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Aljoscha Klose, Daniela Girimonte, Andreas Eichhorn, and Rudolf Kruse
- Subjects
Surface (mathematics) ,Soft computing ,Computer science ,business.industry ,media_common.quotation_subject ,Process (computing) ,Computer vision ,Quality (business) ,Artificial intelligence ,business ,Software ,Interpretability ,media_common - Abstract
Today the method for surface quality analysis of exterior car body panels is still characterized by manual detection of local form deviations and evaluation by experts. The new approach presented in this paper is based on 3D image processing. A major step in this process is the classification of the different kinds of surface form deviations. For this purpose, we compared the performance of different soft-computing techniques. Although the dataset was rather small, high dimensional and unbalanced, we achieved promising results with regard to classification accuracies and interpretability of rule bases.
- Published
- 2005
27. Polyhedral Risk Measures in Stochastic Programming
- Author
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Andreas Eichhorn and Werner Römisch
- Subjects
Mathematical optimization ,Risk measure ,Stability (learning theory) ,Context (language use) ,Coherence (statistics) ,Entropic value at risk ,Mathematical economics ,Software ,Stochastic programming ,Convexity ,Theoretical Computer Science ,Mathematics ,Dual (category theory) - Abstract
We consider stochastic programs with risk measures in the objective and study stability properties as well as decomposition structures. Thereby we place emphasis on dynamic models, i.e., multistage stochastic programs with multiperiod risk measures. In this context, we define the class of polyhedral risk measures such that stochastic programs with risk measures taken from this class have favorable properties. Polyhedral risk measures are defined as optimal values of certain linear stochastic programs where the arguments of the risk measure appear on the right-hand side of the dynamic constraints. Dual representations for polyhedral risk measures are derived and used to deduce criteria for convexity and coherence. As examples of polyhedral risk measures we propose multiperiod extensions of the Conditional-Value-at-Risk.
- Published
- 2005
28. Polyhedral risk measures in electricity portfolio optimization
- Author
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Isabel Wegner, Werner Römisch, and Andreas Eichhorn
- Subjects
Power utility ,Mathematical optimization ,Class (computer programming) ,Computer science ,business.industry ,Portfolio ,Electricity ,Portfolio optimization ,business ,Stochastic programming - Abstract
We compare different multiperiod risk measures taken from the class of polyhedral risk measures with respect to the effect they show when used in the objective of a stochastic program. For this purpose, simulation results of a stochastic programming model for optimizing the electricity portfolio of a German municipal power utility are presented and analyzed. This model aims to minimize risk and expected overall cost simultaneously. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
- Published
- 2004
29. Mean-risk optimization of electricity portfolios
- Author
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Werner Römisch, Nicole Gröwe-Kuska, Isabel Wegner, Andreas Eichhorn, Gorden Spangardt, and Andrea Liebscher
- Subjects
Mathematical optimization ,Horizon (archaeology) ,Discretization ,Computer science ,CVAR ,business.industry ,Portfolio ,Electricity ,Portfolio optimization ,business ,Energy derivative ,Weighting - Abstract
We present a mathematical model with stochastic input data for mean-risk optimization of electricity portfolios containing several physical components and energy derivative products. The model is designed for the optimization horizon of one year in hourly discretization. The aim consists in maximizing the mean book value of the portfolio at the end of the optimization horizon and, at the same time, in minimizing the risk of the portfolio decisions. The risk is measured by the conditional value-at-risk and by some multiperiod extension of CVaR, respectively.We present numerical results for a large-scale realistic problem adapted to a municipal power utility and study the effects of varying weighting of risk. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
- Published
- 2004
30. Homogeneous hydrogenation in supercritical fluids mediated by colloidal catalysts
- Author
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Heiko G. Niessen, Joachim Bargon, Andreas Eichhorn, and Klaus Woelk
- Subjects
Supercritical carbon dioxide ,Chemistry ,Process Chemistry and Technology ,Inorganic chemistry ,Nanoparticle ,Reactivity (chemistry) ,Homogeneous catalysis ,Physical and Theoretical Chemistry ,Heterogeneous catalysis ,Chemical reaction ,Catalysis ,Supercritical fluid - Abstract
As an intermediate form between homogeneous and heterogeneous catalysis, catalysts based on transition metal colloids have drawn a lot of attention in recent years. Mating advantages from different concepts of catalysis, they turn out to be highly active, selective, and, in addition, easily separated from other reaction components. Even though colloidal catalysts are widely used in conventional solvents, hardly anything is known about their reactivity in supercritical fluids such as supercritical carbon dioxide (scCO 2 ). Furthermore, scCO 2 is an especially attractive, non-toxic, and environmentally benign solvent for chemical reactions. When hydrogenations were conducted using polymer-supported colloidal Pd nanoparticles as catalysts in scCO 2 , we found turnover frequencies (TOFs) as high as 4 000 000 h −1 even at a reasonably low hydrogen pressures of 15 bar and temperatures of 50 °C. To our surprise, their reactivity turned out to be much higher than those of most other catalysts reported in the literature. The kinetics of their catalytic reactions in supercritical fluids has been investigated using in situ NMR in combination with a toroid cavity autoclave (TCA).
- Published
- 2002
31. 13C PHIP NMR spectra and polarization transfer during the homogeneous hydrogenation of alkynes with parahydrogen
- Author
-
Joachim Bargon, Andreas Eichhorn, Matthias Stephan, Olaf Kohlmann, and Heiko G. Niessen
- Subjects
NMR spectra database ,Heteronuclear molecule ,Chemistry ,Carbon-13 NMR satellite ,Proton NMR ,Molecule ,General Materials Science ,General Chemistry ,Carbon-13 NMR ,Triple bond ,Spin isomers of hydrogen ,Photochemistry - Abstract
Homogeneously catalyzed hydrogenations of unsaturated substrates with parahydrogen not only lead to strong polarization signals in 1H NMR spectra, but also can give rise to strong heteronuclear polarization, especially if the hydrogenations are carried out in low magnetic fields. As a typical example, the polarization transfer from protons to carbon nuclei during the hydrogenation of alkynes is outlined for several substrates. In systems containing easily accessible triple bonds, e.g. phenylethyne or 3,3-dimethyl-1-butyne, polarization transfer occurs to all carbon nuclei in the molecule. Accordingly, in NMR spectra recorded in situ all 13C resonances can be observed with good to excellent signal-to-noise ratios using only a single transient. The qualitative influence of symmetry and electronic aspects of the substrate and its hydrogenation product on the efficiency of the transfer of polarization to the 13C-nuclei are discussed. Copyright © 2001 John Wiley & Sons, Ltd.
- Published
- 2002
32. Parametric Modeling of Static and Dynamic Processes in Engineering Geodesy
- Author
-
Andreas Eichhorn
- Subjects
Set (abstract data type) ,Engineering ,business.industry ,Ordinary differential equation ,Parametric model ,Finite difference ,Context (language use) ,Focus (optics) ,Geodesy ,business ,Finite element method ,Parametric statistics - Abstract
In this paper, the main focus is set on the utilization of parametric methods for the quantification of causative relationships in static and dynamic deformation processes. Parametric methods are still ‘exotic’ in engineering geodesy but state of the art e.g. in civil and mechanical engineering. Within this context, an essential part is the physical (parametric) modeling of the functional relationships based on partial or ordinary differential equations using the corresponding numerical solutions represented by finite element (FE) or finite difference (FD) models.
- Published
- 2014
33. Indoor localisation for wheeled platforms based on IMU and artificially generated magnetic field
- Author
-
Abdelmoumen Norrdine, Hendrik Hellmers, Jörg Blankenbach, and Andreas Eichhorn
- Subjects
Inertial measurement unit ,Computer science ,Dead reckoning ,Local positioning system ,Real-time computing ,Trajectory ,Electronic engineering ,Context (language use) ,Kinematics ,Kalman filter ,Sensor fusion - Abstract
In recent years the research on positioning and navigation systems for indoor environments has progressed rapidly. For this purpose many technologies based on e.g. UWB, WLAN, ultrasonic or infrared were utilized. However, these systems are restricted on line-of-sight (LOS) conditions due to disturbances, fading and multipath inside of buildings. Because magnetic fields are able to penetrate walls, building materials or other objects, a DC Magnetic signal based Indoor Local Positioning System (MILPS) was developed, which provides localisation in harsh indoor environments. Multiple electrical coils — representing reference stations — and tri-axial magnetometers as mobile stations are utilized. Capturing the magnetic field intensities of at least three different coils leads to the specific slope distances and finally to the observer's position. Because the current positioning algorithm is designed for stop-and-go applications originally, this contribution focuses on the sensor fusion of MILPS and an Inertial Measurement Unit (IMU) to face kinematic applications for wheeled platforms. The short time stable IMU-integrated data, which is influenced by sensor drifts and integration errors, is then supported by MILPS, which delivers positions in a low frequent update interval. To estimate a position in two dimensional environments — in the first step — an Iterative Kaiman Filter (IKF) is applied to eliminate linearization errors caused by inaccurate predictions. Therefore the dead reckoning trajectory is updated by using MILPS' distance observations. In this context first promising experiments with combinations of IMU and MILPS have been performed proving the capability of sensor integration. While acceleration and angular rate measurements lead to a state prediction (consisting of current position and velocity) external MILPS-observations are used for IMU-data support. The IKF estimates a current state in respect to both measurement systems' statistical information.
- Published
- 2014
34. An IMU/magnetometer-based Indoor positioning system using Kalman filtering
- Author
-
Abdelmoumen Norrdine, Jörg Blankenbach, Andreas Eichhorn, and Hendrik Hellmers
- Subjects
Engineering ,business.industry ,Magnetometer ,Local positioning system ,law.invention ,Indoor positioning system ,law ,Inertial measurement unit ,Electronic engineering ,Ultrasonic sensor ,Fading ,business ,Inertial navigation system ,Multipath propagation - Abstract
Many infrastructure-based indoor positioning technologies such as UWB, WLAN, ultrasonic or infrared are limited by disturbances and errors caused by building objects (e.g. walls, ceiling and furniture). Magnetic fields, however, are able to penetrate various obstacles - in this case commonly used (building) materials - without attenuation, fading, multipath or signal delay. Thus, in the past years a DC Magnetic signal based Indoor Local Positioning System (MILPS), which consists of multiple electrical coils as reference stations and tri-axial magnetic sensors as mobile stations was developed. By observing magnetic field intensities of at least three different magnetic coils, position estimation of the magnetic sensors can be carried out even in severe indoor environments. However, the positioning algorithm currently used is designed for stop-and-go localization.
- Published
- 2013
35. Automatic generation of intersection topologies using numerous GPS traces
- Author
-
Dieter Schramm, Peter Zahn, and Andreas Eichhorn
- Subjects
Approximation theory ,Wireless network ,business.industry ,Real-time computing ,Topology (electrical circuits) ,Network topology ,Maschinenbau ,Intersection ,Global Positioning System ,A priori and a posteriori ,business ,Collision avoidance ,Simulation ,Mathematics - Abstract
To provide reliable assistance to drivers at intersections, a priori information has to be supplied to so-called Cooperative Intersection Collision Avoidance Systems (CICAS), such as lane geometry, admissible turning maneuvers, and the areas where the paths of traffic participants typically cross. In the implementation of the CICAS of the project simTD, this information is stored in the intersection topology and transmitted via a wireless network to vehicles approaching an intersection. To achieve high coverage, timeliness and precision of the stored data at the same time, an approach to automatic generation of intersection topologies from noisy measurements is applied, which is based on B-spline curve approximation.
- Published
- 2013
36. Stochastic Optimization of Power Generation and Storage Management in a Market Environment
- Author
-
Andreas Eichhorn
- Subjects
Microeconomics ,Electricity generation ,Order (exchange) ,business.industry ,Electricity market ,Spot market ,Energy market ,Stochastic optimization ,Business ,Process engineering ,Stochastic programming ,Renewable energy - Abstract
This chapter provides an overview of practically applying mathematical optimization techniques to short-term and medium-term planning of a power generation system in a market environment. The considered power generating system may contain thermal plants (gas or coal fired), hydro power plants, new renewables, as well as dedicated energy storages (e.g., gas storages, hydro reservoirs). We argue that stochastic optimization is an appropriate modeling framework in order to take into account the uncertainty of input data (such as natural hydrologic inflows and energy market prices), market decision structures, as well as the optional character of power generating units and energy storages.
- Published
- 2013
37. A Warning Algorithm for Intersection Collision Avoidance
- Author
-
Peter Zahn, Dieter Schramm, and Andreas Eichhorn
- Subjects
Safe driving ,Maschinenbau ,Computer science ,media_common.quotation_subject ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,Advanced driver assistance systems ,Function (engineering) ,Implementation ,Algorithm ,Collision avoidance ,Field (computer science) ,Intersection (aeronautics) ,media_common - Abstract
This paper addresses two challenges for successful implementations of driver assistance systems for providing intersection collision avoidance based on Vehicle-to-Vehicle communication. Firstly, satellite based positioning typically comes along with varying precision, which has to be considered by the warning function. Secondly, a distinction has to be made between critical and safe driver behavior. An ideal warning function for the use in critical driver behavior is one which warns the accident perpetrator early enough so that the driver can defuse the situation on his own, and which remains silent during normal safe driving behavior. The following article develops such a warning algorithm and verifies it using data obtained in a field test. The validation considers to what extent parameterization of the algorithm can resolve the conflict mentioned above between the two goals of a low false-positive warning rate and high capability for accidence avoidance.
- Published
- 2013
38. Maneuver prediction at intersections using cost-to-go gradients
- Author
-
Dieter Schramm, Moritz Werling, Peter Zahn, and Andreas Eichhorn
- Subjects
Jerk ,Model predictive control ,Engineering ,Nonlinear system ,Optimization problem ,Terminal (electronics) ,Maschinenbau ,Control theory ,business.industry ,Advanced driver assistance systems ,Optimal control ,business ,Field (computer science) - Abstract
According to the analysis of car accidents many casualties occur at intersections. As ongoing research demonstrates, Advanced Driver Assistance Systems that aim at preventing this type of accident, need to reliably predict the turning maneuver of all relevant participants in the scene. In this work an approach is introduced, which models human drivers as the optimizer of an optimal control problem with an unknown terminal state. Tracking the cost-to-go gradient to the terminal state of each driving option leads to the most plausible hypothesis. The optimal control problem itself is formulated with costs that minimize jerk, time and steering effort with good resemblance to typical human driving behavior. In combination with a simplified vehicle model this leads to a nonlinear constrained dynamic optimization problem, which is solved numerically. The performance of the proposed approach is evaluated on data obtained in a field test with promising results.
- Published
- 2013
39. Karamell und Schokolade optimal
- Author
-
Andreas Eichhorn
- Abstract
In verschiedenen Situationen in Technik, Wirtschaft oder Politik ist man daran interessiert unter einer Anzahl von moglichen Entscheidungen die jeweils beste auszuwahlen, also die optimale Entscheidung zu treffen, die den grostmoglichen Nutzen bringt. In den meisten Fallen sind Nutzen und Entscheidungsalternativen nicht exakt gegeben, Entscheidungen werden dann entweder sprachlichargumentativ ausgewahlt und begrundet oder gar aus dem Bauch heraus gefallt. In manchen Fallen ist es aber moglich, Entscheidungsalternativen und Nutzen in Zahlen und Formeln so auszudrucken, dass uber diese Beschreibung im Prinzip die optimalen Entscheidungen und der maximale Nutzen festgelegt sind. Dabei ist zu beachten, dass bei mehreren (gleichzeitig oder hintereinander) zu treffenden Entscheidungen gewisse Abhangigkeiten zu berucksichtigen sind, bezuglich der moglichen Alternativen. Wenn beispielsweise die Umsetzung einer bestimmten (Teil-)Entscheidung mit bestimmten Kosten verbunden ware, so stunde dieser Geldbetrag fur andere Entscheidungen nicht mehr zur Verfugung.
- Published
- 2012
40. In situ PHIP NMR — a new tool to investigate hydrogenation mediated by colloidal catalysts
- Author
-
Joachim Bargon, Andreas Eichhorn, and Andreas Koch
- Subjects
inorganic chemicals ,chemistry.chemical_classification ,endocrine system ,Chemistry ,Process Chemistry and Technology ,digestive, oral, and skin physiology ,Alkyne ,Homogeneous catalysis ,Spin isomers of hydrogen ,Photochemistry ,complex mixtures ,Catalysis ,Styrene ,chemistry.chemical_compound ,Colloid ,Phenylacetylene ,Physical and Theoretical Chemistry ,Polarization (electrochemistry) - Abstract
It is known that some colloidal catalysts show “homogeneous”-like behavior, but it is unclear which parameters define the borderline between heterogeneous, i.e. surface reactions, and homogeneous-type catalysis of colloidal systems. The reaction of ethynylbenzene (phenylacetylene) with parahydrogen using the colloidal palladium catalyst Pd x [(N(octyl) 4 Cl] y leads to nuclear spin polarization in the hydrogenation products. Accordingly, the in situ NMR method parahydrogen induced polarization (PHIP) is an appropriate tool to investigate hydrogenation mediated by colloidal catalysts.
- Published
- 2001
41. Stochastic Optimization of Electricity Portfolios: Scenario Tree Modeling and Risk Management
- Author
-
Holger Heitsch, Andreas Eichhorn, and Werner Römisch
- Subjects
Flexibility (engineering) ,Power management ,Mathematical optimization ,business.industry ,Stochastic optimization ,Electricity ,business ,Constructive ,Stochastic programming ,Risk management ,Field (computer science) ,Mathematics - Abstract
We present recent developments in the field of stochastic programming with regard to application in power management. In particular, we discuss issues of scenario tree modeling, that is, appropriate discrete approximations of the underlying stochastic parameters. Moreover, we suggest risk avoidance strategies via the incorporation of so-called polyhedral risk functionals into stochastic programs. This approach, motivated through tractability of the resulting problems, is a constructive framework providing particular flexibility with respect to the dynamic aspects of risk.
- Published
- 2010
42. An adaptive Kalman-filtering approach for the calibration of finite difference models of mass movements
- Author
-
Thilo Schmalz, Volker Buhl, and Andreas Eichhorn
- Subjects
Mathematical optimization ,Computer science ,Calibration (statistics) ,Modeling and Simulation ,Earth and Planetary Sciences (miscellaneous) ,Finite difference method ,Finite difference ,Kalman filter ,Engineering (miscellaneous) ,Algorithm - Published
- 2010
43. Lemmata
- Author
-
Gerrit Walther, Merio Scattola, Ulrich Pfisterer, Georg Satzinger, Saskia Wiedner, Sabine Meine, Sven Externbrink, Reinhold Reith, Georg Stöger, Horst Carl, Barbara Stollberg-Rilinger, Ulrich Hufeld, Sibylle Appuhn-Radtke, Wolfgang E. J. Weber, Robert von Friedeburg, Hans-Joachim König, Susanne Rode-Breymann, Markus Meumann, Stefan Rinke, Mark Hengerer, Katrin Keller, Rainer Babel, Gudrun Gersmann, Wolfgang Schmale, Rolf Reichardt, Dieter Langewiesche, Stefanie Lieb, Edith Koller, Hans-Jürgen Lüsebrink, Christine Siegert, Martin Gierl, Steffen Schlinker, Iris Gareis, Hendrikje Mautner, Achim Mittag, Martin Otto, Hans-Peter Haferkamp, Martin Gabriel, Thomas Schirren, Thomas Synofzik, Mariacarla Gadebusch-Bondio, Wolfgang Behringer, Matthias Tischer, Ignacio Czeguhn, Ulrike Müßig, Onno Poppinga, Rebekka von Mallinckrodt, Wolfgang Altgeld, Martin Wrede, Thomas Töpfer, Axel Flügel, Klaus Wolf, Susanna Layh, Roland Kanz, Günter Butzer, Manuela Günter, Inge Kroppenberg, Dennis F. Mahoney, Frank Büttner, Andreas Eichhorn, Christoph Meinel, Peter Walter, Renko Geffarth, Georg Eckert, Konrad Schneider, Josef Ehmer, Michael Beck, Alexander Weber, Stefan Schweizer, Jürgen Henkel, Jennifer Wasmuth, Jan Willem Veluwenkamp, Hans-Heinrich Nolte, Elena Marasinova, Steffi Bahro, Andreas Bingener, Thomas Bremer, Werner Troßbach, Wolfgang Friedrich, Heiner Lück, Peter Burschel, Wolfgang Seidenspinner, Walter Sparn, Friederike Nüssel, Friedrich Wilhelm Graf, Peter Piasecki, Margarete Zimmermann, Hans Körner, Michael Fessner, Gloria Sanz Lafuente, Markus A. Denzel, Claus Priesner, Andrea Griesebner, Rosa Costa, Rainer Schöller, Anke te Heesen, Regine Mathias, Rebecca Grotjahn, Christoph Deupmann, Stefan Jordan, Kai Bremer, Hubert Moßburger, Jörg Vögele, Dietrich Erben, Staffan Müller-Wille, Gottfried Schiemann, Silvia Serena Tschopp, Edith Saurer, Gisela Wilbertz, Stefan Reichmuth, Johannes Dillinger, Thomas Sing, Peter W. Marx, Beate Agnes Schmidt, Michael North, Silvia Carola Dobler, Bernadette Malinowski, Martin Löhnig, Rainer Brunner, Christoph Kampmann, Carolyn Dougherty, Christoph Bartels, Marcus Popplow, Detlev Ellmers, Eckhard Schinkel, Axel Bayer, Sonja Kinzler, Rita Voltmer, Heiko Laß, Wolfgang Uwe Eckart, Stefan Gorißen, Kim Siebenhüner, Philipp Robinson Rössner, Mark Häberlein, Uwe Meiners, Carsten Goehrke, Stéphanie Chapuis-Després, Martin Laube, Roman Köster, Ulrich Troitzsch, Harald Haarmann, Helmut Bley, Helwig Schmidt-Glintzer, Heiko Frese, Clemens Zimmermann, Marion Hiller, Volker Leppin, Nanny Kim, Dirk Niefanger, Jens Bruning, Ingrid Lohmann, Andreas Rutz, Paul Richard Blum, Katharina Weikl, Eva Brinkschulte, Werner Röcke, Lothar Vogel, Peer Schmidt, Hubert Weitensfelder, R. Johanna Regnath, Thomas Maissen, Friedrich Steinle, Michael Wagner, Christoph Müller, Wilhelm Brauneder, Thomas Beck, John Hattendorf, Helmut Holzhey, Helmut Zander, Christian Möller, Johann Schneider, Birgit Pelzer-Reith, Rudolf Holbach, Tobias Sarx, Alexander Kästner, Arno Strohmeyer, Peter Collin, Daniela Siebe, Matthias Asche, Philippe Hamou, Sicco Lehmann-Brauns, Cornelia Aust, Arne Karsten, Ekkehard Kraft, Camilla Bork, Claudia Jarzebowski, Klaus Antoni, Christian Mathieu, Florian Freitag, Andreas Dix, Kirsten Rüther, Marion Stange, Reinhard Wendt, Jan Lucassen, Leo Lucassen, Klaus Beyrer, and Karin Gludovatz
- Published
- 2010
44. Miltefosine Efficiently Eliminates Leishmania major Amastigotes from Infected Murine Dendritic Cells without Altering Their Immune Functions▿
- Author
-
Esther von Stebut, Andreas Eichhorn, Caroline Gazeau, and Klaus G. Griewank
- Subjects
CD4-Positive T-Lymphocytes ,Phosphorylcholine ,Antigen presentation ,Antiprotozoal Agents ,Leishmaniasis, Cutaneous ,Apoptosis ,Biology ,CD8-Positive T-Lymphocytes ,Microbiology ,Mice ,Immune system ,medicine ,Animals ,Pharmacology (medical) ,Leishmania major ,Antigen-presenting cell ,Mechanisms of Action: Physiological Effects ,Cells, Cultured ,Cell Proliferation ,Pharmacology ,Miltefosine ,Dendritic cell ,Dendritic Cells ,biology.organism_classification ,Leishmania ,Mice, Inbred C57BL ,Infectious Diseases ,Immunology ,Interleukin 12 ,medicine.drug - Abstract
As a treatment for leishmaniasis, miltefosine exerts direct toxic effects on the parasites. Miltefosine also modulates immune cells such as macrophages, leading to parasite elimination via oxidative radicals. Dendritic cells (DC) are critical for initiation of protective immunity against Leishmania through induction of Th1 immunity via interleukin 12 (IL-12). Here, we investigated the effects of miltefosine on DC in Leishmania major infections. When cocultured with miltefosine for 4 days, the majority of in vitro -infected DC were free of parasites. Miltefosine treatment did not influence DC maturation (upregulation of major histocompatibility complex II [MHC II] or costimulatory molecules, e.g., CD40, CD54, and CD86) or significantly alter cytokine release (IL-12, tumor necrosis factor alpha [TNF-α], or IL-10). Further, miltefosine DC treatment did not alter antigen presentation, since unrestricted antigen-specific proliferation of CD4 + and CD8 + T cells was observed upon stimulation with miltefosine-treated, infected DC. In addition, miltefosine application in vivo did not lead to maturation/emigration of skin DC. DC NO − production, a mechanism used by phagocytes to rid themselves of intracellular parasites, was also unaltered upon miltefosine treatment. Our data confirm prior studies indicating that in contrast to, e.g., pentavalent antimonials, miltefosine functions independently of the immune system, mostly through direct toxicity against the Leishmania parasite.
- Published
- 2009
45. [Chlorambucil treatment of Behçet's syndrome. Retrospective evaluation of two cases]
- Author
-
Andreas, Eichhorn, Martin, Siepmann, and Wilhelm, Kirch
- Subjects
Erythema Nodosum ,Behcet Syndrome ,Humans ,Prednisone ,Chlorambucil ,Retrospective Studies - Abstract
Behçet's syndrome rarely occurs in North America and Central Europe (incidence: 1 : 500,000), whereas it is more frequently seen in Japan and Mediterranean countries (incidence: 1 : 10,000). The diagnosis is based on the detection of symptoms and clinical signs. Orogenital aphthosis, anterior and posterior uveitides that frequently cause loss of vision are considered to be primary symptoms. Dermatologic manifestations, i.e., erythema nodosum, vascular lesions (angio-Behçet's syndrome), gastrointestinal ulcers and neurologic involvement, can be observed. HLA B5 is found in some of the patients with Behçet's syndrome. Administration of chlorambucil, a cytotoxic compound, is an effective form of treatment of symptoms and complications of Behçet's syndrome.The present article describes the course of a female and a male patient who were 39 and 23 years old when Behçet's syndrome was diagnosed for the first time. Treatment with chlorambucil was started in the early 1990s and continued for a period of 9 1/2 and 3(3/4) years, respectively, with the symptoms remitting during and after this therapy. Approximately 10 years after the start of treatment with chlorambucil, the patients' symptoms changed. The female patient who was first diagnosed having Behçet's syndrome at the age of 39 years developed rheumatoid arthritis with joint destruction. Her symptoms could be controlled in the long term by oral administration of prednisone, at doses below the Cushing threshold combined with methotrexate. The male patient who was first diagnosed having Behçet's syndrome at the age of 23 years developed systemic vasculitis remitting during low-dose treatment with prednisone.Immunosuppressive therapy with chlorambucil administered over several years often induces remission of Behçet's syndrome. However, both case reports indicate that symptoms can change from Behçet's syndrome to systemic vasculitis or rheumatoid arthritis.
- Published
- 2009
46. Scenario Tree Approximation and Risk Aversion Strategies for Stochastic Optimization of Electricity Production and Trading
- Author
-
Holger Heitsch, Werner Römisch, and Andreas Eichhorn
- Subjects
Mathematical optimization ,Spot contract ,Optimization problem ,Computer science ,Risk aversion ,Spot market ,Probability distribution ,Statistical model ,Stochastic optimization ,Portfolio optimization - Abstract
Dynamic stochastic optimization techniques are highly relevant for applications in electricity production and trading since there are uncertainty factors at different time stages (e.g., demand, spot prices) that can be described reasonably by statistical models. In this paper, two aspects of this approach are highlighted: scenario tree approximation and risk aversion. The former is a procedure to replace a general statistical model (probability distribution), which makes the optimization problem intractable, suitably by a finite discrete distribution. Our methods rest upon suitable stability results for stochastic optimization problems. With regard to risk aversion we present the approach of polyhedral risk measures. For stochastic optimization problems minimizing risk measures from this class it has been shown that numerical tractability as well as stability results known for classical (nonrisk-averse) stochastic programs remain valid. In particular, the same scenario approximation methods can be used. Finally, we present illustrative numerical results from an electricity portfolio optimization model for a municipal power utility.
- Published
- 2009
47. Dynamic risk management in electricity portfolio optimization via polyhedral risk functionals
- Author
-
Werner Römisch and Andreas Eichhorn
- Subjects
Mathematical optimization ,Optimization problem ,Spot contract ,Computer science ,Stochastic process ,business.industry ,Probabilistic logic ,Stochastic programming ,Production (economics) ,Revenue ,Stochastic optimization ,Cash flow ,Portfolio optimization ,business ,Risk management - Abstract
We propose a methodology for combining risk management with optimal planning of power production and trading based on probabilistic knowledge about future uncertainties such as demands and spot prices. Typically, such a joint optimization of risk and (expected) revenue yields additional overall efficiency. Our approach is based on stochastic optimization (stochastic programming) with a risk functional as objective. The latter maps an uncertain cash flow to a real number. In particular, we employ so-called polyhedral risk functionals which, though being non-linear mappings, preserve linearity structures of optimization problems. Therefore, these are favorable to the numerical tractability of the optimization problems. The class of polyhedral risk functionals contains well-known risk functionals such as average-value-at-risk and expected polyhedral utility. Moreover, it is also capable to model different dynamic risk mitigation strategies.
- Published
- 2008
48. Applications of knowledge-based systems in technical surveying
- Author
-
Klaus Chmelina and Andreas Eichhorn
- Subjects
Knowledge-based systems ,Knowledge management ,Quality assessment ,business.industry ,Computer science ,Modeling and Simulation ,Free stationing ,Knowledge engineering ,Earth and Planetary Sciences (miscellaneous) ,Domain knowledge ,business ,Engineering (miscellaneous) - Published
- 2008
49. Lemmata
- Author
-
Ulrich Pfister, Prachi Deshpande, Mathias Mayer, Peter Walter, Hans-Joachim Konig, Wolfgang Petter, Konrad Schneider, Louis Pahlow, Stefan Brakensiek, Christoph Bartels, Gero Steffens, Ian-Otrnar Hesse, Reinhold Reith, Michael Kopsidis, Sibylle Hofer, Rolf Reichardt, Sabine Berthold, Marcus Popplow, Karl Pichol, Michael Mende, Thomas Buchner, Alexander Michael Fischer, Mara R. Wade, Harald Witthoft, Peter Burschel, Wolfgang Schmale, Jörn Henrich, James G Snyder, Christoph Meinel, Wolfgang Behringer, Moritz Epple, Florian Heesch, Hans Niels Jahnke, Michaela Hohkamp, Tim Neu, Dietrich Erben, Ingrid Kummels, Andreas Grünschloß, Gerrit Walther, Ute Schneider, Susanne Rode-Breymann, Niccolò Guicciardini, Jon Miller, Torsten Fried, Alexander Koller, Ulrich Hufeld, Katrin Keller, Wolfgang Uwe Eckart, Robert Jütte, Wolfgang Kaiser, Hinrich Biesterfeldt, Antje Zare, Johanna Bleker, Johanna Bieker, Thomas Synofzik, Werner Wilhelm Schnabel, William G. Naphy, Angelika Dworzak, Gabriele Busch-Salmen, Maria Rößner-Richarz, Jörn Rüsen, Stefan Jordan, Birgitta Bader-Zaar, Diethelm Klippel, Maria Elena Paulus, Iris Gareis, Thomas Sokoll, Oliver Hochadel, Franz Körndle, Markus A. Denzel, Nathanael Riemer, Christian Büschges, Claus Priesner, Georg Toepfer, Walter Sparn, Wilhelm Schmidt-Biggemann, Bernhard Fritscher, Steve O’Malley, Burkhard Moennighoff, Helmut Bley, Claudia Strieter, Rita Gudermann, Martin Löhnig, Jan Lucassen, Leo Lucassen, Jutta Schickore, Barbara Orland, Bernhard R. Kroener, Daniel Hohrath, Markus Meumanna, Fritz Dross, Achim Hofer, Angela Strauß, Cordula Kapser, Karoline Noack, Kirsten Rüther, Barend J. ter Haar, Carsten Zelle, Roland Kanz, Stéphanie Chapuls-Després, Max Sebastián Hering Torres, Martin Rothkege, Sandra Hindriks, Rainer Babel, Wilhelm Brauneder, Friedrich Huber, Stefan Rinke, Kocku von Stuckrad, Margareth Lanzinge, Anne Conrad, Caspar Hirschi, Annette Kreutzlger-Herr, Oliver Werner, Ulinka Rublack, Brigitte Söleh, Friedrich Jaeger, Grischka Petr, Katharina Hottmann, Dirk Niefanger, Alf Christophersen, Heidrun Rosenberg, Stephan Conermann, Ronald G. Asch, Jöm Leonhard, Wolfgang E. J. Weber, Benedikt Mertens, Dorothea Wendebourg, Rudolf Prokschi, Sebastian Maximilian Hacker, Ulrich Theobald, Sabine Meine, Kai Bremer, Jan-Otmar Hesse, Martin Ohst, Staffan Müller-Wille, Rainer Siotta, Ekkehard Westermann, Angelika Westermann, Michael Fessner, Ulrike Weckel, Harald Maihold, Katharina Reinholdt, Jörg Vögele, Stefan Reichmuth, Joachim Gierlichs, Franz Korndle, Dietmar Bleidick, Thorsten Keiser, Michaela Kalusok, Joachim Kremer, Michael Fischer, Martin Petzoldt, Irenäus Totzke, Ruth Müller-Lindenberg, Wolfgang Rathert, Christine Siegert, Arne Spohr, Andreas Eichhorn, Annette Kreutziger-Herr, Hendrikje Mautner, Rainer Bayreuthera, Bernd Redmann, Matthias Tischer, Albert Schirrmeister, Andreas Gestrich, Volker Leppin, Erich Bryner, Karl Erich Grözinger, Rita Voltmer, Jörg Requate, Christopher Spehr, Edith Koller, Julia Carrasco, Ernst Gerhard Eder, Bernward Seiter, Renate Blickle, Rosa Kohlheim, Volker Kohlheim, Hans Rudolf Velten, Reinhard Stauber, Nils Freytag, Gunter Mahlerwein, Rupert Klieber, Harald Haarmann, Claudia Ulrich, Heinrich Best, Jörn Sieglerschmidt, Birgit Biehler, Kristin Marek, and Marianne Klemun
- Published
- 2008
50. WiKaF - A Knowledge-based Kalman-Filter for Pedestrian Positioning
- Author
-
Andreas Eichhorn, Michael Thienelt, and Alexander Reiterer
- Subjects
Computer science ,Hybrid positioning system ,business.industry ,media_common.quotation_subject ,Real-time computing ,Pedestrian ,Kalman filter ,Precondition ,Position (vector) ,Dead reckoning ,Location-based service ,Quality (business) ,Computer vision ,Artificial intelligence ,business ,media_common - Abstract
The precise, reliable and preferably ubiquitous positioning of mobile users is a substantial precondition for the provision of location and situation based information by Location Based Services. Within these applications, determining the location of pedestrians in ‘passive environment’ represents a special challenge. In this paper a new knowledge-based approach for the improvement of position quality is presented.
- Published
- 2007
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