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Among adolescents, acute intoxications caused by drugs as well as intoxications caused by toxic substances make up an important chapter of emergency pediatric pathology. We conducted a retrospective study carried out for a period of 1 year, 2021–2022, which included a number of 37 patients, admitted in the Pediatric Clinic of the County Clinical Hospital “Sfântul Apostol Andrei” Constanța. Out of the total of admissions during a 12 months period, 0,5% consisted in acute intoxications in adolescents. There is a higher tendency for substance intoxication in females (65,5% of total cases). There is a higher tendency for adolescents with suicide ideation to use substances in order to end their life because of multiple risk factors, mental health disorders putting them at a higher risk to attempt suicide. Alcohol is widely used.

Hypertrophic pyloric stenosis (HPS) is a gastrointestinal condition that affects newborns and young infants and is characterized by progressive, non-bilious projectile vomiting. This study aimed to investigate the demographics and clinical manifestations of HPS. A retrospective, non-randomized study was conducted over a period of three years (2019-2022) and included 29 patients diagnosed with HPS at the Pediatric Clinic of the County Clinical Emergency Hospital of Constanta. The results showed a significant male predilection, with a ratio of 1:4.8, and a seasonal variation with a higher incidence of HPS in the summer months. The primary symptom of HPS was non-bilious forceful vomiting after feeding, observed in nearly all cases. Other symptoms included dehydration, stagnation and decrease in weight. The thickness of the pyloric muscle was measured using ultrasonography and was found to be an average of 54.5 mm, with a range between 30 mm and 79 mm, which is considered a strong indication of HPS. This study highlights the importance of considering HPS as a possible diagnosis in newborns and young infants presenting with symptoms of projectile vomiting, and emphasizes the need for further research into the seasonal variation of HPS and its underlying causes.