116 results on '"Andel, D"'
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2. Pre-existing Subclones Determine Radioresistance in Rectal Cancer Organoids
- Author
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Andel, D., primary, Viergever, B.J., additional, Peters, N.A., additional, Raats, D.A.E., additional, van Schelven, S.J., additional, Intven, M.P.W., additional, Zandvliet, M., additional, Hagendoorn, J., additional, Rinkes, I.H.M. Borel, additional, and Kranenburg, O., additional
- Published
- 2023
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3. CO2 WAG Huff-N-Puff for Waterflooded Conventional Reservoirs: Design and Field Learnings from Deployment in the Permian Basin of West Texas
- Author
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Bandyopadhyay, P., additional, Andel, D., additional, Hampton, D. W., additional, and Stone, L. D., additional
- Published
- 2023
- Full Text
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4. Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)
- Author
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Spiers, H, Kouli, O, Ahmed, W, Varley, R, Ahari, D, Argus, L, Mclean, K, Kamarajah, S, Coe, P, Griffiths, E, Chan, A, Macutkiewicz, C, Jamdar, S, Wilson, M, Fullwood, C, Toogood, G, Gilchrist, A, Goldsworthy, M, Rashid, M, Pockney, P, Varela, J, Brindl, N, Ramirez, J, Marafante, C, Iwao, Y, Ghzawi, A, Elhadi, M, Gacaferi, H, Varghese, C, Adeyeye, A, Alser, O, Teh, C, Prieto, M, Hasan, A, Al-Naggar, H, Salgado, R, Veracierto, F, Lancelotti, T, Solinas, D, Oddi, R, Garcia, F, Mazza Diez, E, Andrade Ramirez, M, Bracco, R, Fernandez, D, Maraschio, M, Obeide, L, Giordano, E, Alcaraz, A, Marani, M, Aguirre, N, Luna, F, Francesconi, M, Chiham, F, Ramos Cossio, R, Alvarez, F, Pantoja Pachajoa, D, Mandojana, F, Merlo, I, Gonzalez, M, Cervelo, G, Puma, R, Vardaro, G, Davis, A, Jurat, D, Guenoff, C, Raubenheimer, K, Goddard, K, Brown, K, Wegrecki, K, Cheung, H, Yang, M, Siddiqui, J, Ahn, J, Huynh, R, Lam, Y, Afzal, M, Ong, B, Chua, M, Ly, K, Thomson, J, Watson, D, Dawson, A, Drane, A, Van Ruyven, S, Lun, E, Ferguson, M, Jeong, J, De Silva, C, Wills, V, Gundara, J, Mccourt, E, Bong, C, Tabone, R, Wong, W, Gray, A, Koh, D, Pollock, M, Singhal, S, Smith, R, Dudi-Venkata, N, Kanhere, H, Stranz, C, Seow, W, Mansour, L, Wormald, J, Loveday, B, Thomson, B, O'Donnell, T, Milenkovski, N, Herath, M, Trochsler, M, Farfus, A, Maddern, G, Bunjo, Z, Kuan, L, Atanasov, G, Samadov, E, Namazov, I, Asgarov, M, Ibrahimli, A, Srinivasan, M, Saeed, M, Aljawder, H, Juma, I, Coimbra, F, Marques, N, Casteleins, W, Petruzziello, A, Jabur, G, Rodriguez, J, Buso, P, Mackenzie, S, Hsiao, M, Sljivic, I, Tecson, A, Karanicolas, P, Roke, R, Moon, J, Butler, E, Riquelme, F, Yanez, M, Catan, F, Uribe, M, Carriel, F, Oppliger, F, Paredes, A, Daroch, D, Aguayo, J, Perez Rivera, C, Acosta Buitrago, L, Kadamani Abiyomaa, A, Mosquera Paz, M, Cabrera, P, Corso, J, Ozcay, N, Ozant, A, Arslan, K, Besim, H, Almezghwi, H, Azzam, A, Bessa, S, El-Sayes, I, Badawy, A, Wael, M, El-Gendi, A, Azab, M, Fayed, M, El Kassas, M, Gamal, M, Tawheed, A, Al Shafie, A, Emile, S, Elfallal, A, Elfeki, H, Shalaby, M, Sakr, A, Elbahnasawy, M, Shama, M, Abdel-Elsalam, W, Abd-Elsalam, S, Escobar Dominguez, J, Medrano, F, Gaitan, S, Escalon Gonzalez, O, Alfaro Varela, J, Cea, M, Interiano, M, Cabrera, B, Lakkis, Z, Georges, P, Antonot, C, Magnin, J, Kamphues, C, Lauscher, J, Schineis, C, Loch, F, Lee, L, Beyer, K, Bouchagier, K, Galanis, I, Bartziotas, D, Lostoridis, E, Tourountzi, P, Nagorni, E, Charalabopoulos, A, Baili, E, Kyros, E, Vagios, I, Skotsimara, A, Liakakos, T, Alexandrou, A, Papalampros, A, Papadopolous, V, Tooulias, A, Kentarchos, I, Christou, C, Tsoulfas, G, Tale-Rosales, L, Lopez Muralles, I, Melendez, H, Bran, G, Monroy Mahecha, F, Contreras, J, Porras, D, Paiz, E, Soto, E, Ixcayau Hernandez, J, Gupta, A, Rajput, D, Kumar, N, Mani, R, Kant, R, Sonkar, A, Anand, A, Agrawal, M, Gaurav, K, Tripathi, M, Sikora, S, Bharathy, K, Kumar Rangapa, M, Khuller, D, Bhojwwani, R, Ayyar, S, Jain, N, Mehraj, A, Hussain, F, Nazir, I, Shah, M, Chowdri, N, Hilmi, A, Argenio, G, Atelli, P, Palladino, E, Armellino, M, Tamini, N, Nespoli, L, Degrate, L, Angrisani, M, Carissimi, F, Bordoni, P, Fleres, F, Clarizia, G, Spolini, A, Franzini, M, Cucinotta, E, Badessi, G, Mazzeo, C, Viscosi, F, Pintabona, G, Campagnaro, T, Poletto, E, Turri, G, Ruzzenente, A, Conci, S, Guglielmi, A, Feo, C, Fabbri, N, Fazzin, M, Giaccari, S, Massani, M, Pelizzo, P, Colella, M, Tutino, R, Cappellacci, F, Medas, F, Canu, G, Erdas, E, Calo, P, Porcu, A, Perra, T, Scanu, A, Fancellu, A, Germani, P, Giunta, C, Biloslavo, A, Abdallah, H, Aizza, G, Barberis, A, Belli, F, Santoliquido, M, Filauro, M, Canonico, G, Nelli, T, Di Martino, C, Capezzuoli, L, Anastasi, A, Bressan, L, Cortinovis, S, Nagliati, C, Colombo, F, Ferrario, L, Bondurri, A, Guerci, C, Maffioli, A, Catena, F, Perrone, G, Giuffrida, M, Morini, A, Annicchiarico, A, Gallo, G, Carpino, A, Ferrari, F, De Paola, G, Sammarco, G, Callari, C, Licari, L, Sorce, V, Di Miceli, D, Lovisetto, F, Zonta, S, Chessa, A, Fiorini, A, De Manzoni Garberini, A, Angelini, E, Moggia, E, Murgese, A, Mungo, S, Birolo, S, Garino, M, Pipitone Federico, N, Muratore, A, Lunghi, E, Calabro, M, Cianci, P, Enrico, R, Capuzzolo, S, Cafagna, L, Minafra, M, Sasia, D, Gattolin, A, Migliore, M, Rimonda, R, Travaglio, E, De Marco, G, Elter, C, Bargellini, T, D'Amico, S, Zambonin, D, Caponi, A, Calini, G, Puggioni, A, Bresadola, V, Zalla, T, Cantafio, S, Feroci, F, Romoli, L, Giudicissi, R, Picciariello, A, Papagni, V, Dibra, R, Altomare, D, Pinotti, E, Montuori, M, Baronio, G, Tonini, V, Sartarelli, L, Gori, A, Cervellera, M, Lapolla, P, Sapienza, P, Brachini, G, Cirillo, B, Zambon, M, Mingoli, A, Pascariello, A, Boccia, L, Benedetti, S, Mantovani, G, De Angelis, M, Ferrara, F, Testa, V, Borghi, F, Maione, F, Pruiti Ciarello, V, Giraudo, G, Agresta, F, Cestaro, G, Prando, D, Cavallo, F, Zese, M, Cillara, N, Sechi, R, Cardia, R, Cannavera, A, Putzu, G, Frongia, F, Pisanu, A, Delogu, D, Esposito, G, Podda, M, Iossa, A, De Angelis, F, Boru, C, Silecchia, G, Palini, G, Garulli, G, Veneroni, S, Tammaro, P, Maida, P, Leake, P, Wanliss, M, Sato, K, Chiyonobu, N, Imamura, H, Yamazaki, S, Watanabe, M, Qasem, A, Ayasra, F, Al Dahabrh, S, Khaled, A, Alsaafin, S, Al-Thunaibat, A, Olaywah, D, Alqudah, S, Alqawasmi, S, Khamees, A, Guboug, A, Es Salim, M, Althwabteh, T, Bani Khaled, H, El-Hammuri, N, Aljesrawi, A, Alamaadany, F, Eljareh, M, Al Gasi, A, Alsaeiti, S, Alkhafeefi, A, Suliaman, T, Alanasri, A, Haroun, A, Haron, A, Kilani, A, Ahmed, M, Alawami, M, Alawami, A, Albashri, M, Abusannuga, M, Malek, A, Jwaili, N, Aldenfria, A, Elzwawi, F, Almugaddami, A, Egdeer, A, Masoud, M, Alazzabi, B, Alezabi, B, Shuwayyah, A, Alkamkhe, A, Aboulqasim, I, Atiyah, H, Alfagi, R, Abdulmula, A, Bouhuwaish, A, Samer, A, Salim, R, Aboazamazem, H, Almiqlash, B, Biala, M, Alganimi, W, Ghamgh, R, Ben Omar, N, Alsoufi, A, Aldreawi, M, Saleim, N, Sowan, F, Saleem, H, Ahmed, A, Samalavicius, N, Aliosin, O, Dailidenas, S, Dulskas, A, Buckus, B, Kuliesius, Z, Bradunaite, R, Dominguez-Rosado, I, Buerba, G, Posadas-Trujillo, O, Alfaro-Goldaracena, A, Cortes, R, Mercado, M, Beristain-Hernandez, J, Mora-Munoz, V, Mena-Bedolla, J, Palacios Ramirez, A, Astorga Medina, M, Van Aert, G, Ombashi, S, Spillenaar Bilgen, R, Vos, D, Besselink, M, Alberts, V, Busch, O, Bemelman, W, Boermeester, M, Daams, F, Gordinou De Gouberville, M, Van Duijvendijk, P, De Graaff, M, Baaij, J, Gans, S, Bos, K, Goudsmit, B, Den Dekker, B, Braat, A, Kuijpers, A, Breukers, S, Borel Rinkes, I, Andel, D, Hayes, T, Carson, D, Bhat, S, Van Der Have, J, Anderson, C, Bissett, I, Windsor, J, Elliott, B, Scowcroft, H, Mclauchlan, J, Ritchie, D, Jeffery, F, Connor, S, Xu, W, Mashlan, H, Thirayan, V, Ly, J, Mcguinness, M, Ferguson, L, Watt, I, Harmston, C, Akinmade, A, Enoch, E, Kayode-Nissi, V, Ogundele, I, Ayoade, B, Adekoya, A, Nwokoro, C, Opadeyi, A, Yusuf, A, Ojajuni, A, Adepoju, O, Muhammad Dauda, M, Keffi Mubarak, M, Lawal, K, Muhammad, D, Salonga, D, Sael, N, Rey, C, Pestano, M, Tan, D, Bangayan, N, Sy, D, Ang, D, Bernardo, E, Chua, J, Alharthi, M, Bukhari, W, Bakier Mohammed, K, Al Athath, S, Ghunaim, M, Saiedi, H, Sultan, N, Farsi, A, Basendowah, M, Malibary, N, Jaloun, H, Altalhi, D, Organjee, A, Moamena, M, Al Zaidi, T, Alyami, M, Alqannas, M, Al-Urfan, M, Elawad, A, Alawadhi, A, Alalawi, Y, Alqarni, A, Alqahtani, B, Alayed, A, Alsobaie, K, Adi, H, Elhaj, M, Dehlawi, A, Behairy, G, Khaled, I, Kmezic, S, Radenkovic, D, Aleksic, L, Markovic, V, Pejovic, I, Antic, A, Kalkan, M, Vujanovic Gadjanski, O, Dusan, S, Marcetic, B, Thiruchelvam, N, Chiow, A, Mun, D, Tan, E, Koh, Y, Loh, W, Wang, Z, Chan, C, Kloppers, C, Almgla, N, Bernon, M, Kahn, M, Karimbocus, N, Roldan Villavicencio, J, Goitia, V, Gutierrez Rios, R, Garcia Ruiz, S, Lopez Deogracias, M, Turrado-Rodriguez, V, Morales, X, Hessheimer, A, Termes Serra, R, Beltran De Heredia, J, Trujillo-Diaz, J, Herreros-Rodriguez, J, Montes-Manrique, M, De Andres-Asenjo, B, Beltran-Heredia, J, Gimenez Maurel, T, Utrilla Fornals, A, Martin Anoro, L, Cortese, S, Perez Diaz, M, Ballon, M, Morote, M, Cebolla Rojas, L, Oliver Guillen, J, Lopez De Fernandez, A, Del Campo Lavilla, M, Mora-Guzman, I, Escartin, A, Pinillos, A, Vela Polanco, F, Jara Quezada, J, Muriel Alvarez, P, Tur-Martinez, J, Camps, J, Herrero, E, Garcia-Domingo, M, Cugat Andorra, E, Crespi Mir, A, Claramonte Bellmunt, O, Vicens Arbona, J, Fernandez Burgos, I, Sarriugarte Lasarte, A, Marin, H, Tellaeche De La Iglesia, M, Ocerin Alganza, O, Salinas Gomez, J, Ramos-Martin, P, Urbieta, A, Nasimi Sabbagh, R, Castell Gomez, J, Serrablo, A, Paterna -Lopez, S, GutiCrossed D SignCopyrightrrez-Diez, M, Abadia-Forcen, M, Serradilla-Martin, M, Duran Munoz-Cruzado, V, Pareja Ciuro, F, Perea Del Pozo, E, Aparicio Sanchez, D, Dios-Barbeito, S, Marenco De La Cuadra, B, Retamar Gentil, M, Reguera-Rosal, J, Infantes Ormad, M, Lopez-Ruiz, J, Landaluce-Olavarria, A, Zevallos-Quiroz, J, Barrutia Leonardo, J, Emaldi, A, Begona, E, Balciscueta Coltell, I, Sebastian, M, Martinez Ramos, S, Martinez Alcaide, S, Lorenzo Perez, J, Martinez Insfran, L, Lopez-Morales, P, Gimenez Frances, C, Rahy-Martin, A, Pelloni, M, Ortiz-Lopez, D, Benet-Munoz, O, Pinero-Gonzalez, L, Alconchel, F, Nicolas-Lopez, T, Rodrigues, K, Cascales Campos, P, Gomez-Bosch, F, Ramirez Romero, P, Ibrahim, M, Hamid, H, Idres, R, Idris, M, Mohammed, O, Ayran, S, Sinan, A, Ozben, V, Aytac, E, Aliyeva, Z, Mutlu, A, Bilgin, I, Karahasanoglu, T, Hamzaoglu, I, Bozkirli, B, Uprak, T, Kotan, T, Coskun, M, Kara, Y, Somuncu, E, Kocatas, A, Bozkurt, M, Demirli Atici, S, Kaya, T, Sert, I, Emiroglu, M, Jaffar, M, Younis, M, Aziz, T, Ikram, F, Sandal, M, Al Madhloum Al Suwaidi, F, Alshaikh, M, Saber, A, Khammas, A, Nessa, A, Jardine, R, Nicol, L, Clark, C, Mcgee, A, Alkari, B, Feretis, M, Antakia, R, Georgiades, F, Moneim, J, O'Neill, R, Balakrishnan, A, Lunevicius, R, Sud, A, Moutsos, I, Gomez, D, Shahid, S, Majeed, T, Ibrahim, W, Kadum, K, Melia, R, Magee, C, Chicken, D, Kumar, S, Alshibshoubi, M, Van Laarhoven, S, Dewi, F, Williams, J, Byrne, B, Wilkerson, P, Tang, C, Farhangmehr, N, Jonas, A, Charavanamuttu, V, Almeida, K, Efthimiou, E, Boardley, J, White, A, Butt, M, Menzies, D, Gundkalli, Z, Hassanzadeh-Baboli, D, Jones, O, Mistry, P, Saha, S, Gerrard, A, Evans, J, Rajeev, S, Ali, W, Ross, E, Gilliam, A, Hitchins, C, Emslie, K, Spellar, K, Sked, H, Briggs, C, Brown, L, A Hemadasa, N, Apollos, J, Belgaumkar, A, Tawfik, A, Brewin, L, Oyewole, B, Wadhawan, H, Massie, E, Rutherford, D, Mcgivern, K, Mcelroy, L, De'Ath, H, Tobbal, M, Nagendram, S, Patel, P, Handa, S, Houghton, G, Sundaralingam, S, Parker, J, Morgan, R, Gala, T, Ibrahim, S, Harby, R, Abdelkarim, M, Holroyd, D, Thomas, R, Mclennan, E, Boardley, R, Jamieson, N, Ebied, H, Gossage, J, Davies, A, Wheatstone, S, Jawad, Z, Jiao, L, Rajagopal, P, Sodergren, M, Lami, M, Wiberg, A, Bond-Smith, G, Gemmill, E, Lenzi, E, Sapre, D, Herrod, P, Boyd-Carson, H, Garcea, G, Issa, E, Jackson, A, Fashina, T, Pan, H, Farquharson, B, Shafiq, H, Emanuel, O, Mahdi, S, Jeyarajah, S, Finch, L, Whiting, G, Pigott, L, Martin, J, Siriwardena, A, Beatson, K, Abawi, L, Lam, W, Rea, W, Andrews, B, Al-Sarireh, B, Soliman, F, Burridge, J, Jenvey, C, Hammoda, M, Hollyman, M, Merker, L, Richards, J, Sukumaran, V, Rogers, S, Payne, C, Bibi, S, Raza, K, Ul Ain, N, Dronamraju, S, Patil, S, Nachimuthu, S, Ravindran, S, Patel, S, Ivanov, B, Patel, M, Ejtehadi, F, Jebamani, J, Akhter Rahman, M, Woodun, H, De Prendergast, A, Afzal, A, Bota, E, Abdul, S, Karmarkar, R, Crockett, E, Evans, L, Appleton, B, Dada, O, Kulkarni, R, Albirnawi, H, Gravestock, P, Vincenti, C, Taribagil, S, Dent, B, Tse, C, Clayton, B, Burdekin, E, Bannister, L, Alam, I, Gray, J, Mactier, M, Pollock, A, Gough, V, Kanchustambam, S, Ridgway, M, Arujunan, K, Gopalswamy, S, Monteiro De Barros, J, Lyons, T, Griffith, D, Awan, A, Latif, J, Bandlamudi, N, Bhatti, I, Raptis, D, Machairas, N, Pissanou, T, Mestre-Costa, J, Hidalgo Salinas, C, Pollok, J, Al-Ardah, M, Watson-Jones, E, Rontree-Carey, T, Boyce, T, Hawkin, P, Elmaradny, A, Ross, K, Adu-Peprah, E, Pinto, K, Dunne, D, Mccready, R, Nita, G, Szatmary, P, Tay, V, Rajput, K, Rajendran, I, Chaudhury, M, Zambas, G, Swaminathan, C, Atif, Q, Barrow, T, Williams, O, Malik, A, Conroy, S, Lindley, S, Gilmore, K, Boden, E, Richards, S, Hraishawi, I, Polak, P, Mclaughlin, D, Deeny, D, Shuttleworth, R, Harris, A, Peilober-Richardson, A, Morris, G, Sara, X, Almourad, H, Ang, Y, Smyth, R, Ding, D, Foster, J, Bond, A, Kumar, Y, Ahmad, A, Radoi, D, Alkaili-Alyamani, A, Balakrishnan, S, Satchidanand, R, Danwaththa Liyanage, A, Blake, I, Ransome, M, Weerasinghe, C, Kenington, C, Mayo, K, Mohammed, M, Cockbain, A, Peckham-Cooper, A, Mccauley, G, Gordon, C, Smith, A, Hawkins, W, Chakravartty, S, Baillie, C, Kenny, R, Kumar, A, Koimtzis, G, Bellamy, E, Menon, A, Kanakala, A, Nevins, E, Madhavan, A, Thulasiraman, S, France, K, O'Connor, A, Idama, D, Raslan, C, Sridhar, S, Parveen, M, Mubashar, T, Jarvis, S, Cakmak, I, Wright, C, Andrews, S, Abdelsaid K Abdul Aal, Y, Jayasankar, B, Morilla, J, Shehata, M, Subba, N, Tewari, N, El-Sayed, C, Somaie, D, Beheiry, N, Douka, E, Arumugam, S, Wijetunga, I, Leivers, E, Ibrahim, B, Khan, K, Wheat, J, Christopher, J, Barnett, R, Elberm, H, Booker, J, Ashai, S, Berry, D, Luhmann, A, Sgro, A, Galea, M, Jeyakumar, J, Marriott, P, Zafar, S, Baker, A, Yershov, D, Galanopoulos, G, Jordan, R, Peinado Garcia, C, Anyaugo, N, Bath, M, Omatseye, J, Roberts, L, Argyriou, E, Machesney, M, Parmar, C, Clark, S, Khalil, H, Unsworth, S, Mlotshwa, M, Ayoub, N, Aboelkhair, A, Iosif, E, Mohamed, N, Reynolds, E, Mackender, E, Robinson, D, Mufti, W, Fischkoff, K, Coleman, N, Anantha Sathyanarayana, S, Deutsch, G, Giangola, M, Lin, D, Weiss, M, Chung, C, Nguyen, A, Mueller, J, Dabit, M, Gordon, J, Mcguire, E, Rashid, O, Georgi, E, Gallo, M, Kunstman, J, Peters, N, O'Connor, R, Bhattacharya, B, Onkendi, E, Santos, A, Richmond, R, Warren, M, Zhang, K, Broderick, R, Clary, B, Horgan, S, Doucet, J, Liepert, A, Harmon, L, Mccall, C, Sham, J, Williams, E, Labadie, K, Clark, N, Dickerson, L, Hammill, C, Williams, G, Kushner, B, Cos, H, Zarate Rodriguez, J, Bailey, K, Al-Raimi, I, Al-Zazay, K, Ahmed Mohammed Al-Mahdi, S, Mohammed Aldowbli, S, Al-Shehari, M, Shream, S, Al-Ameri, S, Aeed, M, Aldawbali, M, Alsayadi, R, Alsayadi, M, Spiers H. V. M., Kouli O., Ahmed W. U., Varley R., Ahari D., Argus L., McLean K. A., Kamarajah S. K., Coe P., Griffiths E. A., Chan A. K. C., Macutkiewicz C., Jamdar S., Wilson M., Fullwood C., Toogood G., McLean K., Ahmed W., Gilchrist A., Goldsworthy M., Rashid M., Pockney P., Varela J., Brindl N., Ramirez J., Marafante C., Iwao Y., Ghzawi A., Elhadi M., Gacaferi H., Varghese C., Adeyeye A., Alser O., Teh C., Prieto M., Hasan A., Al-Naggar H., Salgado R., Veracierto F., Lancelotti T., Solinas D., Oddi R., Garcia F. W., Mazza Diez E., Andrade Ramirez M. R., Bracco R., Fernandez D., Maraschio M. A., Obeide L., Giordano E., Alcaraz A., Marani M. A., Aguirre N., Luna F., Francesconi M., Chiham F., Ramos Cossio R., Alvarez F. A., Pantoja Pachajoa D. A., Mandojana F., Merlo I. G., Gonzalez M. H., Cervelo G., Puma R., Vardaro G. F., Davis A., Jurat D., Guenoff C., Raubenheimer K., Goddard K., Brown K., Wegrecki K. J., Cheung H. Y. C., Yang M., Cheung H., Siddiqui J., Ahn J. H., Huynh R., Lam Y. H., Afzal M., Ong B. S., Chua M. Y. M., Ly K., Thomson J. E., Watson D., Dawson A. C., Drane A., Van Ruyven S., Lun E. W. Y., Ferguson M., Jeong J. Y., De Silva C., Wills V., Gundara J., McCourt E., Bong C., Tabone R., Wong W. J., Gray A., Koh D., Pollock M., Singhal S., Smith R., Dudi-Venkata N. N., Kanhere H., Stranz C., Seow W., Mansour L. T., Wormald J., Loveday B. P. T., Thomson B., O'Donnell T., Milenkovski N., Herath M., Trochsler M., Farfus A., Maddern G., Bunjo Z., Kuan L. L., Atanasov G., Dawson A., Lun E., Samadov E., Namazov I., Asgarov M., Ibrahimli A., Srinivasan M., Saeed M. F., Aljawder H., Juma I., Coimbra F. J., Marques N., Casteleins W. A., Petruzziello A., Jabur G., Rodriguez J. F. P., Buso P. L., Mackenzie S., Hsiao M., Sljivic I., Tecson A., Karanicolas P. J., Roke R., Moon J., Butler E. V., Riquelme F., Yanez M., Catan F., Uribe M., Carriel F., Oppliger F., Paredes A., Daroch D., Aguayo J. C., Perez Rivera C. J., Acosta Buitrago L. M., Kadamani Abiyomaa A., Mosquera Paz M. S., Cabrera P., Corso J., Ozcay N., Ozant A., Arslan K., Besim H., Almezghwi H., Azzam A. Y., Bessa S., El-Sayes I., Badawy A., Wael M., El-Gendi A., Azab M. A., Fayed M., El Kassas M., Gamal M., Tawheed A., Al Shafie A., Emile S., Elfallal A., Elfeki H., Shalaby M., Sakr A., Elbahnasawy M., Shama M., Abdel-Elsalam W., Abd-Elsalam S., Escobar Dominguez J. E., Medrano F., Gaitan S., Escalon Gonzalez O. M., Alfaro Varela J. C., Cea M., Interiano M., Cabrera B., Lakkis Z., Georges P., Antonot C., Magnin J., Kamphues C., Lauscher J. C., Schineis C., Loch F. N., Lee L. D., Beyer K., Bouchagier K., Galanis I., Bartziotas D., Lostoridis E., Tourountzi P., Nagorni E. A., Charalabopoulos A., Baili E., Kyros E., Vagios I., Skotsimara A., Liakakos T., Alexandrou A., Papalampros A., Papadopolous V., Tooulias A., Kentarchos I., Christou C., Tsoulfas G., Tale-Rosales L. F., Lopez Muralles I., Melendez H., Bran G., Monroy Mahecha F. A., Contreras J. R., Porras D. E., Paiz E., Soto E. R., Ixcayau Hernandez J. R., Gupta A., Rajput D., Kumar N., Mani R., Kant R., Sonkar A. A., Anand A., Agrawal M. K., Gaurav K., Tripathi M., Sikora S., Bharathy K., Kumar Rangapa M., Khuller D. S., Bhojwwani R., Ayyar S., Jain N., Mehraj A., Hussain F., Nazir I., Shah M., Chowdri N. A., Hilmi A., Argenio G., Atelli P., Palladino E., Armellino M. F., Tamini N., Nespoli L. C., Degrate L., Angrisani M., Carissimi F., Bordoni P., Fleres F., Clarizia G., Spolini A., Franzini M., Cucinotta E., Badessi G., Mazzeo C., Viscosi F., Pintabona G., Campagnaro T., Poletto E., Turri G., Ruzzenente A., Conci S., Guglielmi A., Feo C., Fabbri N., Fazzin M., Giaccari S., Feo C. V., Massani M., Pelizzo P., Colella M., Tutino R., Cappellacci F., Medas F., Canu G. L., Erdas E., Calo P. G., Porcu A., Perra T., Scanu A. M., Feo C. F., Fancellu A., Germani P., Giunta C., Biloslavo A., Abdallah H., Aizza G., Barberis A., Belli F., Santoliquido M., Filauro M., Canonico G., Nelli T., Di Martino C., Capezzuoli L., Anastasi A., Bressan L., Cortinovis S., Nagliati C., Colombo F., Ferrario L., Bondurri A., Guerci C., Maffioli A., Catena F., Perrone G., Giuffrida M., Morini A., Annicchiarico A., Gallo G., Carpino A., Ferrari F., De Paola G., Sammarco G., Callari C., Licari L., Sorce V., Di Miceli D., Lovisetto F., Zonta S., Chessa A., Fiorini A., De Manzoni Garberini A., Angelini E., Moggia E., Murgese A., Mungo S., Birolo S. L., Garino M., Pipitone Federico N. S., Muratore A., Lunghi E. G., Calabro M., Cianci P., Enrico R., Capuzzolo S., Cafagna L., Minafra M., Sasia D., Gattolin A., Migliore M., Rimonda R., Travaglio E., De Marco G., Elter C., Bargellini T., D'Amico S., Zambonin D., Caponi A., Calini G., Puggioni A., Bresadola V., Zalla T., Cantafio S., Feroci F., Romoli L., Giudicissi R., Picciariello A., Papagni V., Dibra R., Altomare D. F., Pinotti E., Montuori M., Baronio G., Tonini V., Sartarelli L., Gori A., Cervellera M., Lapolla P., Sapienza P., Brachini G., Cirillo B., Zambon M., Mingoli A., Pascariello A., Boccia L., Benedetti S., Mantovani G., De Angelis M., Ferrara F., Testa V., Borghi F., Maione F., Pruiti Ciarello V., Giraudo G., Agresta F., Cestaro G., Prando D., Cavallo F., Zese M., Cillara N., Sechi R., Cardia R., Cannavera A., Putzu G., Frongia F., Pisanu A., Delogu D., Esposito G., Podda M., Iossa A., De Angelis F., Boru C., Silecchia G., Palini G. M., Garulli G., Veneroni S., Tammaro P., Maida P., Leake P. A., Wanliss M. G., Sato K., Chiyonobu N., Imamura H., Yamazaki S., Watanabe M., Qasem A., Ayasra F., Al Dahabrh S., Khaled A., Alsaafin S., Al-Thunaibat A., Olaywah D., Alqudah S., Alqawasmi S., Khamees A., Guboug A., Es Salim M., Althwabteh T., Bani Khaled H., El-Hammuri N., Aljesrawi A., Alamaadany F., Eljareh M., Al Gasi A. E. J., Alsaeiti S., Alkhafeefi A. S., Suliaman T., Alanasri A. H. A., Haroun A. B. A., Haron A., Kilani A. I., Ahmed M., Alawami M., Alawami A., Albashri M., Abusannuga M., Malek A., Jwaili N., Aldenfria A., Elzwawi F., Almugaddami A., Egdeer A. S. A., Masoud M., Alazzabi B., Alezabi B., Shuwayyah A., Alkamkhe A. A. S., Aboulqasim I., Atiyah H., Alfagi R. A. A., Abdulmula A., Bouhuwaish A., Samer A., Salim R., Aboazamazem H., Almiqlash B., Biala M., Alganimi W., Ghamgh R., Ben Omar N., Alsoufi A., Aldreawi M., Saleim N., Sowan F., Saleem H., Ahmed A., Samalavicius N. E., Aliosin O., Dailidenas S., Dulskas A., Buckus B., Kuliesius Z., Bradunaite R., Dominguez-Rosado I., Buerba G. A., Posadas-Trujillo O. E., Alfaro-Goldaracena A., Cortes R., Mercado M. A., Beristain-Hernandez J. L., Mora-Munoz V. S., Mena-Bedolla J. M., Palacios Ramirez A. R., Astorga Medina M. M., Van Aert G., Ombashi S., Spillenaar Bilgen R., Vos D., Besselink M., Alberts V., Busch O., Bemelman W., Boermeester M., Daams F., Gordinou De Gouberville M., Van Duijvendijk P., De Graaff M., Baaij J., Gans S., Bos K., Goudsmit B., Den Dekker B., Braat A., Kuijpers A., Breukers S., Borel Rinkes I., Andel D., Hayes T., Carson D., Bhat S., Van Der Have J., Anderson C., Bissett I., Windsor J., Elliott B. M., Scowcroft H., McLauchlan J., Ritchie D., Jeffery F., Connor S., Xu W., Mashlan H., Thirayan V., Ly J., McGuinness M. J., Ferguson L., Watt I., Harmston C., Akinmade A., Enoch E., Kayode-Nissi V., Ogundele I., Ayoade B. A., Adekoya A., Nwokoro C., Opadeyi A., Yusuf A., Ojajuni A., Adepoju O., Muhammad Dauda M., Keffi Mubarak M., Lawal K., Muhammad D., Salonga D., Sael N. A., Rey C. M., Pestano M., Tan D., Bangayan N. R., Sy D. K., Ang D., Bernardo E., Chua J. P., Alharthi M., Bukhari W., Bakier Mohammed K., Al Athath S., Ghunaim M., Saiedi H., Sultan N., Farsi A., Basendowah M., Malibary N., Jaloun H., Altalhi D., Organjee A., Moamena M., Al Zaidi T. M., Alyami M., Alqannas M., Al-Urfan M., Elawad A., Alawadhi A., Alalawi Y., Alqarni A., Alqahtani B., Alayed A., Alsobaie K., Adi H., Elhaj M., Dehlawi A., Behairy G., Khaled I., Kmezic S., Radenkovic D., Aleksic L., Markovic V., Pejovic I., Antic A., Kalkan M., Vujanovic Gadjanski O., Dusan S., Marcetic B., Thiruchelvam N., Chiow A. K. H., Lee L. S., Mun D. Y. C., Tan E. K., Koh Y. X., Loh W. L., Wang Z., Chan C. Y., Kloppers C., Almgla N., Bernon M., Kahn M., Karimbocus N., Roldan Villavicencio J. I., Goitia V., Gutierrez Rios R. D., Garcia Ruiz S., Lopez Deogracias M., Turrado-Rodriguez V., Morales X., Hessheimer A., Termes Serra R., Beltran De Heredia J., Trujillo-Diaz J., Herreros-Rodriguez J., Montes-Manrique M., De Andres-Asenjo B., Beltran-Heredia J., Gimenez Maurel T., Utrilla Fornals A., Martin Anoro L. F., Cortese S., Perez Diaz M. D., Ballon M., Morote M., Cebolla Rojas L., Oliver Guillen J. R., Lopez De Fernandez A., Del Campo Lavilla M., Mora-Guzman I., Escartin A., Pinillos A., Vela Polanco F. F., Jara Quezada J. H., Muriel Alvarez P., Tur-Martinez J., Camps J., Herrero E., Garcia-Domingo M. I., Cugat Andorra E., Crespi Mir A., Claramonte Bellmunt O., Vicens Arbona J. C., Fernandez Burgos I. R., Sarriugarte Lasarte A., Marin H., Tellaeche De La Iglesia M., Ocerin Alganza O., Salinas Gomez J., Ramos-Martin P., Urbieta A., Nasimi Sabbagh R., Castell Gomez J. T., Serrablo A., Paterna -Lopez S., GutiCrossed D SignCopyrightrrez-Diez M., Abadia-Forcen M. T., Serradilla-Martin M., Duran Munoz-Cruzado V. 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D., Tobbal M., Nagendram S., Patel P., Handa S., Houghton G., Sundaralingam S. S., Parker J., Morgan R., Gala T., Ibrahim S., Harby R., Abdelkarim M., Holroyd D., Thomas R., McLennan E., Boardley R., Jamieson N. B., Ebied H., Gossage J., Davies A., Wheatstone S., Jawad Z., Jiao L., Rajagopal P., Sodergren M., Lami M., Wiberg A., Bond-Smith G., Gemmill E., Lenzi E., Sapre D., Herrod P., Boyd-Carson H., Garcea G., Issa E., Jackson A., Fashina T., Pan H., Farquharson B., Shafiq H., Emanuel O., Mahdi S., Jeyarajah S., Finch L., Whiting G., Pigott L., Martin J., Siriwardena A. K., Beatson K., Abawi L., Lam W., Rea W., Andrews B., Al-Sarireh B., Soliman F., Burridge J., Jenvey C., Hammoda M., Hollyman M., Merker L., Richards J., Sukumaran V., Rogers S., Payne C., Bibi S., Raza K., Ul Ain N., Dronamraju S., Patil S., Nachimuthu S., Ravindran S., Patel S., Ivanov B., Patel M., Ejtehadi F., Jebamani J., Akhter Rahman M. M., Woodun H., De Prendergast A., Afzal A., Bota E., Abdul S. R., Karmarkar R., Crockett E., Evans L., Appleton B., Griffiths E., Dada O., Kulkarni R., Albirnawi H., Gravestock P., Vincenti C., Taribagil S., Dent B., Tse C., Clayton B., Burdekin E., Bannister L., Alam I., Gray J., Mactier M., Pollock A., Gough V., Kanchustambam S. R., Ridgway M., Arujunan K., Gopalswamy S., Monteiro De Barros J., Lyons T., Griffith D., Awan A. K., Latif J., Bandlamudi N., Bhatti I., Raptis D. A., Machairas N., Pissanou T., Mestre-Costa J., Hidalgo Salinas C., Pollok J. M., Al-Ardah M., Watson-Jones E., Rontree-Carey T., Boyce T., Hawkin P., Elmaradny A., Ross K., Adu-Peprah E., Pinto K., Dunne D., McCready R., Nita G., Szatmary P., Tay V. L., Rajput K., Rajendran I., Chaudhury M., Zambas G., Swaminathan C., Atif Q. A. A., Barrow T., Williams O., Malik A., Conroy S., Lindley S., Gilmore K., Boden E., Richards S. K., Hraishawi I., Polak P., McLaughlin D., Deeny D., Shuttleworth R., Harris A., Peilober-Richardson A., Morris G. C., Sara X., Almourad H., Ang Y., Smyth R., Ding D., Foster J., Bond A., Kumar Y., Ahmad A., Radoi D., Alkaili-Alyamani A., Balakrishnan S., Satchidanand R. Y., Danwaththa Liyanage A. S., Blake I., Ransome M., Weerasinghe C., Kenington C., Mayo K., Mohammed M., Cockbain A. J., Peckham-Cooper A., McCauley G., Gordon C., Smith A., Hawkins W., Chakravartty S., Baillie C., Kenny R., Kumar A., Koimtzis G., Bellamy E., Menon A., Kanakala A., Nevins E. J., Madhavan A., Thulasiraman S., France K., O'Connor A., Idama D., Raslan C., Sridhar S., Parveen M., Mubashar T., Jarvis S., Cakmak I., Wright C., Andrews S., Abdelsaid K Abdul Aal Y., Jayasankar B., Morilla J., Shehata M., Subba N., Tewari N., El-Sayed C., Somaie D., Beheiry N., Douka E., Arumugam S., Wijetunga I., Leivers E., Ibrahim B., Khan K., Wheat J., Christopher J., Barnett R., Elberm H., Booker J., Ashai S., Berry D., Luhmann A., Sgro A., Rashid M. M., Galea M., Jeyakumar J., Marriott P., Zafar S., Baker A., Yershov D., Galanopoulos G., Jordan R., Peinado Garcia C., Anyaugo N., Bath M. F., Omatseye J., Roberts L., Argyriou E. O., Machesney M., Parmar C., Clark S., Khalil H., Unsworth S., Mlotshwa M., Ayoub N., Aboelkhair A., Iosif E., Mohamed N., Reynolds E., Mackender E., Robinson D., Mufti W., Fischkoff K., Coleman N., Anantha Sathyanarayana S., Deutsch G., Giangola M., Lin D., Weiss M., Chung C., Nguyen A., Mueller J., Dabit M., Gordon J., McGuire E., Rashid O., Georgi E., Gallo M., Kunstman J. W., Peters N. V., O'Connor R., Bhattacharya B., Onkendi E., Santos A. P., Richmond R., Warren M., Zhang K., Broderick R., Clary B., Horgan S., Doucet J., Liepert A., Harmon L., McCall C., Sham J. G., Williams E., Labadie K. P., Clark N. M., Dickerson L. K., Hammill C. W., Williams G., Kushner B., Cos H., Zarate Rodriguez J., Bailey K., Al-Raimi I. M. N., Al-Zazay K., Ahmed Mohammed Al-Mahdi S., Mohammed Aldowbli S., Al-Shehari M., Shream S., Al-Ameri S., Aeed M., Aldawbali M., Alsayadi R., Alsayadi M., Spiers, H, Kouli, O, Ahmed, W, Varley, R, Ahari, D, Argus, L, Mclean, K, Kamarajah, S, Coe, P, Griffiths, E, Chan, A, Macutkiewicz, C, Jamdar, S, Wilson, M, Fullwood, C, Toogood, G, Gilchrist, A, Goldsworthy, M, Rashid, M, Pockney, P, Varela, J, Brindl, N, Ramirez, J, Marafante, C, Iwao, Y, Ghzawi, A, Elhadi, M, Gacaferi, H, Varghese, C, Adeyeye, A, Alser, O, Teh, C, Prieto, M, Hasan, A, Al-Naggar, H, Salgado, R, Veracierto, F, Lancelotti, T, Solinas, D, Oddi, R, Garcia, F, Mazza Diez, E, Andrade Ramirez, M, Bracco, R, Fernandez, D, Maraschio, M, Obeide, L, Giordano, E, Alcaraz, A, Marani, M, Aguirre, N, Luna, F, Francesconi, M, Chiham, F, Ramos Cossio, R, Alvarez, F, Pantoja Pachajoa, D, Mandojana, F, Merlo, I, Gonzalez, M, Cervelo, G, Puma, R, Vardaro, G, Davis, A, Jurat, D, Guenoff, C, Raubenheimer, K, Goddard, K, Brown, K, 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F., Fancellu A., Germani P., Giunta C., Biloslavo A., Abdallah H., Aizza G., Barberis A., Belli F., Santoliquido M., Filauro M., Canonico G., Nelli T., Di Martino C., Capezzuoli L., Anastasi A., Bressan L., Cortinovis S., Nagliati C., Colombo F., Ferrario L., Bondurri A., Guerci C., Maffioli A., Catena F., Perrone G., Giuffrida M., Morini A., Annicchiarico A., Gallo G., Carpino A., Ferrari F., De Paola G., Sammarco G., Callari C., Licari L., Sorce V., Di Miceli D., Lovisetto F., Zonta S., Chessa A., Fiorini A., De Manzoni Garberini A., Angelini E., Moggia E., Murgese A., Mungo S., Birolo S. L., Garino M., Pipitone Federico N. S., Muratore A., Lunghi E. G., Calabro M., Cianci P., Enrico R., Capuzzolo S., Cafagna L., Minafra M., Sasia D., Gattolin A., Migliore M., Rimonda R., Travaglio E., De Marco G., Elter C., Bargellini T., D'Amico S., Zambonin D., Caponi A., Calini G., Puggioni A., Bresadola V., Zalla T., Cantafio S., Feroci F., Romoli L., Giudicissi R., Picciariello A., Papagni V., Dibra R., Altomare D. F., Pinotti E., Montuori M., Baronio G., Tonini V., Sartarelli L., Gori A., Cervellera M., Lapolla P., Sapienza P., Brachini G., Cirillo B., Zambon M., Mingoli A., Pascariello A., Boccia L., Benedetti S., Mantovani G., De Angelis M., Ferrara F., Testa V., Borghi F., Maione F., Pruiti Ciarello V., Giraudo G., Agresta F., Cestaro G., Prando D., Cavallo F., Zese M., Cillara N., Sechi R., Cardia R., Cannavera A., Putzu G., Frongia F., Pisanu A., Delogu D., Esposito G., Podda M., Iossa A., De Angelis F., Boru C., Silecchia G., Palini G. M., Garulli G., Veneroni S., Tammaro P., Maida P., Leake P. A., Wanliss M. 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A., Adekoya A., Nwokoro C., Opadeyi A., Yusuf A., Ojajuni A., Adepoju O., Muhammad Dauda M., Keffi Mubarak M., Lawal K., Muhammad D., Salonga D., Sael N. A., Rey C. M., Pestano M., Tan D., Bangayan N. R., Sy D. K., Ang D., Bernardo E., Chua J. P., Alharthi M., Bukhari W., Bakier Mohammed K., Al Athath S., Ghunaim M., Saiedi H., Sultan N., Farsi A., Basendowah M., Malibary N., Jaloun H., Altalhi D., Organjee A., Moamena M., Al Zaidi T. M., Alyami M., Alqannas M., Al-Urfan M., Elawad A., Alawadhi A., Alalawi Y., Alqarni A., Alqahtani B., Alayed A., Alsobaie K., Adi H., Elhaj M., Dehlawi A., Behairy G., Khaled I., Kmezic S., Radenkovic D., Aleksic L., Markovic V., Pejovic I., Antic A., Kalkan M., Vujanovic Gadjanski O., Dusan S., Marcetic B., Thiruchelvam N., Chiow A. K. H., Lee L. S., Mun D. Y. C., Tan E. K., Koh Y. X., Loh W. L., Wang Z., Chan C. Y., Kloppers C., Almgla N., Bernon M., Kahn M., Karimbocus N., Roldan Villavicencio J. I., Goitia V., Gutierrez Rios R. D., Garcia Ruiz S., Lopez Deogracias M., Turrado-Rodriguez V., Morales X., Hessheimer A., Termes Serra R., Beltran De Heredia J., Trujillo-Diaz J., Herreros-Rodriguez J., Montes-Manrique M., De Andres-Asenjo B., Beltran-Heredia J., Gimenez Maurel T., Utrilla Fornals A., Martin Anoro L. F., Cortese S., Perez Diaz M. D., Ballon M., Morote M., Cebolla Rojas L., Oliver Guillen J. R., Lopez De Fernandez A., Del Campo Lavilla M., Mora-Guzman I., Escartin A., Pinillos A., Vela Polanco F. F., Jara Quezada J. H., Muriel Alvarez P., Tur-Martinez J., Camps J., Herrero E., Garcia-Domingo M. I., Cugat Andorra E., Crespi Mir A., Claramonte Bellmunt O., Vicens Arbona J. C., Fernandez Burgos I. R., Sarriugarte Lasarte A., Marin H., Tellaeche De La Iglesia M., Ocerin Alganza O., Salinas Gomez J., Ramos-Martin P., Urbieta A., Nasimi Sabbagh R., Castell Gomez J. T., Serrablo A., Paterna -Lopez S., GutiCrossed D SignCopyrightrrez-Diez M., Abadia-Forcen M. T., Serradilla-Martin M., Duran Munoz-Cruzado V. 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U., Aziz T., Ikram F., Sandal M., Al Madhloum Al Suwaidi F., Alshaikh M. O., Saber A., Khammas A., Nessa A., Jardine R., Nicol L., Clark C., McGee A., Alkari B., Feretis M., Antakia R., Georgiades F., Moneim J., O'Neill R., Balakrishnan A., Lunevicius R., Sud A., Moutsos I., Gomez D., Shahid S., Majeed T., Ibrahim W. K. G., Kadum K., Melia R., Magee C., Chicken D. W., Kumar S., Alshibshoubi M., Van Laarhoven S., Dewi F., Williams J., Byrne B., Wilkerson P., Tang C. B., Farhangmehr N., Jonas A., Charavanamuttu V., Almeida K., Efthimiou E., Boardley J., White A., Butt M. A., Menzies D., Gundkalli Z., Hassanzadeh-Baboli D., Jones O., Mistry P., Saha S., Gerrard A., Evans J., Rajeev S., Ali W., Ross E., Gilliam A., Hitchins C., Emslie K., Spellar K., Sked H., Briggs C., Brown L., A Hemadasa N., Apollos J. R., Belgaumkar A., Tawfik A., Brewin L., Oyewole B., Wadhawan H., Massie E., Rutherford D., McGivern K., McElroy L., De'Ath H. D., Tobbal M., Nagendram S., Patel P., Handa S., Houghton G., Sundaralingam S. S., Parker J., Morgan R., Gala T., Ibrahim S., Harby R., Abdelkarim M., Holroyd D., Thomas R., McLennan E., Boardley R., Jamieson N. B., Ebied H., Gossage J., Davies A., Wheatstone S., Jawad Z., Jiao L., Rajagopal P., Sodergren M., Lami M., Wiberg A., Bond-Smith G., Gemmill E., Lenzi E., Sapre D., Herrod P., Boyd-Carson H., Garcea G., Issa E., Jackson A., Fashina T., Pan H., Farquharson B., Shafiq H., Emanuel O., Mahdi S., Jeyarajah S., Finch L., Whiting G., Pigott L., Martin J., Siriwardena A. K., Beatson K., Abawi L., Lam W., Rea W., Andrews B., Al-Sarireh B., Soliman F., Burridge J., Jenvey C., Hammoda M., Hollyman M., Merker L., Richards J., Sukumaran V., Rogers S., Payne C., Bibi S., Raza K., Ul Ain N., Dronamraju S., Patil S., Nachimuthu S., Ravindran S., Patel S., Ivanov B., Patel M., Ejtehadi F., Jebamani J., Akhter Rahman M. M., Woodun H., De Prendergast A., Afzal A., Bota E., Abdul S. R., Karmarkar R., Crockett E., Evans L., Appleton B., Griffiths E., Dada O., Kulkarni R., Albirnawi H., Gravestock P., Vincenti C., Taribagil S., Dent B., Tse C., Clayton B., Burdekin E., Bannister L., Alam I., Gray J., Mactier M., Pollock A., Gough V., Kanchustambam S. R., Ridgway M., Arujunan K., Gopalswamy S., Monteiro De Barros J., Lyons T., Griffith D., Awan A. K., Latif J., Bandlamudi N., Bhatti I., Raptis D. A., Machairas N., Pissanou T., Mestre-Costa J., Hidalgo Salinas C., Pollok J. M., Al-Ardah M., Watson-Jones E., Rontree-Carey T., Boyce T., Hawkin P., Elmaradny A., Ross K., Adu-Peprah E., Pinto K., Dunne D., McCready R., Nita G., Szatmary P., Tay V. L., Rajput K., Rajendran I., Chaudhury M., Zambas G., Swaminathan C., Atif Q. A. A., Barrow T., Williams O., Malik A., Conroy S., Lindley S., Gilmore K., Boden E., Richards S. K., Hraishawi I., Polak P., McLaughlin D., Deeny D., Shuttleworth R., Harris A., Peilober-Richardson A., Morris G. C., Sara X., Almourad H., Ang Y., Smyth R., Ding D., Foster J., Bond A., Kumar Y., Ahmad A., Radoi D., Alkaili-Alyamani A., Balakrishnan S., Satchidanand R. Y., Danwaththa Liyanage A. S., Blake I., Ransome M., Weerasinghe C., Kenington C., Mayo K., Mohammed M., Cockbain A. J., Peckham-Cooper A., McCauley G., Gordon C., Smith A., Hawkins W., Chakravartty S., Baillie C., Kenny R., Kumar A., Koimtzis G., Bellamy E., Menon A., Kanakala A., Nevins E. J., Madhavan A., Thulasiraman S., France K., O'Connor A., Idama D., Raslan C., Sridhar S., Parveen M., Mubashar T., Jarvis S., Cakmak I., Wright C., Andrews S., Abdelsaid K Abdul Aal Y., Jayasankar B., Morilla J., Shehata M., Subba N., Tewari N., El-Sayed C., Somaie D., Beheiry N., Douka E., Arumugam S., Wijetunga I., Leivers E., Ibrahim B., Khan K., Wheat J., Christopher J., Barnett R., Elberm H., Booker J., Ashai S., Berry D., Luhmann A., Sgro A., Rashid M. M., Galea M., Jeyakumar J., Marriott P., Zafar S., Baker A., Yershov D., Galanopoulos G., Jordan R., Peinado Garcia C., Anyaugo N., Bath M. F., Omatseye J., Roberts L., Argyriou E. O., Machesney M., Parmar C., Clark S., Khalil H., Unsworth S., Mlotshwa M., Ayoub N., Aboelkhair A., Iosif E., Mohamed N., Reynolds E., Mackender E., Robinson D., Mufti W., Fischkoff K., Coleman N., Anantha Sathyanarayana S., Deutsch G., Giangola M., Lin D., Weiss M., Chung C., Nguyen A., Mueller J., Dabit M., Gordon J., McGuire E., Rashid O., Georgi E., Gallo M., Kunstman J. W., Peters N. V., O'Connor R., Bhattacharya B., Onkendi E., Santos A. P., Richmond R., Warren M., Zhang K., Broderick R., Clary B., Horgan S., Doucet J., Liepert A., Harmon L., McCall C., Sham J. G., Williams E., Labadie K. P., Clark N. M., Dickerson L. K., Hammill C. W., Williams G., Kushner B., Cos H., Zarate Rodriguez J., Bailey K., Al-Raimi I. M. N., Al-Zazay K., Ahmed Mohammed Al-Mahdi S., Mohammed Aldowbli S., Al-Shehari M., Shream S., Al-Ameri S., Aeed M., Aldawbali M., Alsayadi R., and Alsayadi M.
- Abstract
https://www.scopus.com/record/display.uri?eid=2-s2.0-85138595712&origin=inward&txGid=728c82ff11b9726b5d443216a91e7ffa#:~:text=Background: This study,of this pandemic.
- Published
- 2022
5. STEPPING BEYOND COUNTS, FEASIBILITY OF PASSIVELY COLLECTED QUALITATIVE GAIT METRICS USING A SMARTPHONE-BASED CARE MANAGEMENT PLATFORM FOLLOWING TOTAL JOINT ARTHROPLASTY
- Author
-
Fary, C., primary, Abshagen, S., additional, Van Andel, D., additional, Ren, A.N., additional, Anderson, M.B., additional, and Klar, B., additional
- Published
- 2023
- Full Text
- View/download PDF
6. Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)
- Author
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Spiers H. V. M., Kouli O., Ahmed W. U., Varley R., Ahari D., Argus L., McLean K. A., Kamarajah S. K., Coe P., Griffiths E. A., Chan A. K. C., Macutkiewicz C., Jamdar S., Wilson M., Fullwood C., Toogood G., McLean K., Ahmed W., Gilchrist A., Goldsworthy M., Rashid M., Pockney P., Varela J., Brindl N., Ramirez J., Marafante C., Iwao Y., Ghzawi A., Elhadi M., Gacaferi H., Varghese C., Adeyeye A., Alser O., Teh C., Prieto M., Hasan A., Al-Naggar H., Salgado R., Veracierto F., Lancelotti T., Solinas D., Oddi R., Garcia F. W., Mazza Diez E., Andrade Ramirez M. R., Bracco R., Fernandez D., Maraschio M. A., Obeide L., Giordano E., Alcaraz A., Marani M. A., Aguirre N., Luna F., Francesconi M., Chiham F., Ramos Cossio R., Alvarez F. A., Pantoja Pachajoa D. A., Mandojana F., Merlo I. G., Gonzalez M. H., Cervelo G., Puma R., Vardaro G. F., Davis A., Jurat D., Guenoff C., Raubenheimer K., Goddard K., Brown K., Wegrecki K. J., Cheung H. Y. C., Yang M., Cheung H., Siddiqui J., Ahn J. H., Huynh R., Lam Y. H., Afzal M., Ong B. S., Chua M. Y. M., Ly K., Thomson J. E., Watson D., Dawson A. C., Drane A., Van Ruyven S., Lun E. W. Y., Ferguson M., Jeong J. Y., De Silva C., Wills V., Gundara J., McCourt E., Bong C., Tabone R., Wong W. J., Gray A., Koh D., Pollock M., Singhal S., Smith R., Dudi-Venkata N. N., Kanhere H., Stranz C., Seow W., Mansour L. T., Wormald J., Loveday B. P. T., Thomson B., O'Donnell T., Milenkovski N., Herath M., Trochsler M., Farfus A., Maddern G., Bunjo Z., Kuan L. L., Atanasov G., Dawson A., Lun E., Samadov E., Namazov I., Asgarov M., Ibrahimli A., Srinivasan M., Saeed M. F., Aljawder H., Juma I., Coimbra F. J., Marques N., Casteleins W. A., Petruzziello A., Jabur G., Rodriguez J. F. P., Buso P. L., Mackenzie S., Hsiao M., Sljivic I., Tecson A., Karanicolas P. J., Roke R., Moon J., Butler E. V., Riquelme F., Yanez M., Catan F., Uribe M., Carriel F., Oppliger F., Paredes A., Daroch D., Aguayo J. C., Perez Rivera C. J., Acosta Buitrago L. M., Kadamani Abiyomaa A., Mosquera Paz M. S., Cabrera P., Corso J., Ozcay N., Ozant A., Arslan K., Besim H., Almezghwi H., Azzam A. Y., Bessa S., El-Sayes I., Badawy A., Wael M., El-Gendi A., Azab M. A., Fayed M., El Kassas M., Gamal M., Tawheed A., Al Shafie A., Emile S., Elfallal A., Elfeki H., Shalaby M., Sakr A., Elbahnasawy M., Shama M., Abdel-Elsalam W., Abd-Elsalam S., Escobar Dominguez J. E., Medrano F., Gaitan S., Escalon Gonzalez O. M., Alfaro Varela J. C., Cea M., Interiano M., Cabrera B., Lakkis Z., Georges P., Antonot C., Magnin J., Kamphues C., Lauscher J. C., Schineis C., Loch F. N., Lee L. D., Beyer K., Bouchagier K., Galanis I., Bartziotas D., Lostoridis E., Tourountzi P., Nagorni E. A., Charalabopoulos A., Baili E., Kyros E., Vagios I., Skotsimara A., Liakakos T., Alexandrou A., Papalampros A., Papadopolous V., Tooulias A., Kentarchos I., Christou C., Tsoulfas G., Tale-Rosales L. F., Lopez Muralles I., Melendez H., Bran G., Monroy Mahecha F. A., Contreras J. R., Porras D. E., Paiz E., Soto E. R., Ixcayau Hernandez J. R., Gupta A., Rajput D., Kumar N., Mani R., Kant R., Sonkar A. A., Anand A., Agrawal M. K., Gaurav K., Tripathi M., Sikora S., Bharathy K., Kumar Rangapa M., Khuller D. S., Bhojwwani R., Ayyar S., Jain N., Mehraj A., Hussain F., Nazir I., Shah M., Chowdri N. A., Hilmi A., Argenio G., Atelli P., Palladino E., Armellino M. F., Tamini N., Nespoli L. C., Degrate L., Angrisani M., Carissimi F., Bordoni P., Fleres F., Clarizia G., Spolini A., Franzini M., Cucinotta E., Badessi G., Mazzeo C., Viscosi F., Pintabona G., Campagnaro T., Poletto E., Turri G., Ruzzenente A., Conci S., Guglielmi A., Feo C., Fabbri N., Fazzin M., Giaccari S., Feo C. V., Massani M., Pelizzo P., Colella M., Tutino R., Cappellacci F., Medas F., Canu G. L., Erdas E., Calo P. G., Porcu A., Perra T., Scanu A. M., Feo C. F., Fancellu A., Germani P., Giunta C., Biloslavo A., Abdallah H., Aizza G., Barberis A., Belli F., Santoliquido M., Filauro M., Canonico G., Nelli T., Di Martino C., Capezzuoli L., Anastasi A., Bressan L., Cortinovis S., Nagliati C., Colombo F., Ferrario L., Bondurri A., Guerci C., Maffioli A., Catena F., Perrone G., Giuffrida M., Morini A., Annicchiarico A., Gallo G., Carpino A., Ferrari F., De Paola G., Sammarco G., Callari C., Licari L., Sorce V., Di Miceli D., Lovisetto F., Zonta S., Chessa A., Fiorini A., De Manzoni Garberini A., Angelini E., Moggia E., Murgese A., Mungo S., Birolo S. L., Garino M., Pipitone Federico N. S., Muratore A., Lunghi E. G., Calabro M., Cianci P., Enrico R., Capuzzolo S., Cafagna L., Minafra M., Sasia D., Gattolin A., Migliore M., Rimonda R., Travaglio E., De Marco G., Elter C., Bargellini T., D'Amico S., Zambonin D., Caponi A., Calini G., Puggioni A., Bresadola V., Zalla T., Cantafio S., Feroci F., Romoli L., Giudicissi R., Picciariello A., Papagni V., Dibra R., Altomare D. F., Pinotti E., Montuori M., Baronio G., Tonini V., Sartarelli L., Gori A., Cervellera M., Lapolla P., Sapienza P., Brachini G., Cirillo B., Zambon M., Mingoli A., Pascariello A., Boccia L., Benedetti S., Mantovani G., De Angelis M., Ferrara F., Testa V., Borghi F., Maione F., Pruiti Ciarello V., Giraudo G., Agresta F., Cestaro G., Prando D., Cavallo F., Zese M., Cillara N., Sechi R., Cardia R., Cannavera A., Putzu G., Frongia F., Pisanu A., Delogu D., Esposito G., Podda M., Iossa A., De Angelis F., Boru C., Silecchia G., Palini G. M., Garulli G., Veneroni S., Tammaro P., Maida P., Leake P. A., Wanliss M. G., Sato K., Chiyonobu N., Imamura H., Yamazaki S., Watanabe M., Qasem A., Ayasra F., Al Dahabrh S., Khaled A., Alsaafin S., Al-Thunaibat A., Olaywah D., Alqudah S., Alqawasmi S., Khamees A., Guboug A., Es Salim M., Althwabteh T., Bani Khaled H., El-Hammuri N., Aljesrawi A., Alamaadany F., Eljareh M., Al Gasi A. E. J., Alsaeiti S., Alkhafeefi A. S., Suliaman T., Alanasri A. H. A., Haroun A. B. A., Haron A., Kilani A. I., Ahmed M., Alawami M., Alawami A., Albashri M., Abusannuga M., Malek A., Jwaili N., Aldenfria A., Elzwawi F., Almugaddami A., Egdeer A. S. A., Masoud M., Alazzabi B., Alezabi B., Shuwayyah A., Alkamkhe A. A. S., Aboulqasim I., Atiyah H., Alfagi R. A. A., Abdulmula A., Bouhuwaish A., Samer A., Salim R., Aboazamazem H., Almiqlash B., Biala M., Alganimi W., Ghamgh R., Ben Omar N., Alsoufi A., Aldreawi M., Saleim N., Sowan F., Saleem H., Ahmed A., Samalavicius N. E., Aliosin O., Dailidenas S., Dulskas A., Buckus B., Kuliesius Z., Bradunaite R., Dominguez-Rosado I., Buerba G. A., Posadas-Trujillo O. E., Alfaro-Goldaracena A., Cortes R., Mercado M. A., Beristain-Hernandez J. L., Mora-Munoz V. S., Mena-Bedolla J. M., Palacios Ramirez A. R., Astorga Medina M. M., Van Aert G., Ombashi S., Spillenaar Bilgen R., Vos D., Besselink M., Alberts V., Busch O., Bemelman W., Boermeester M., Daams F., Gordinou De Gouberville M., Van Duijvendijk P., De Graaff M., Baaij J., Gans S., Bos K., Goudsmit B., Den Dekker B., Braat A., Kuijpers A., Breukers S., Borel Rinkes I., Andel D., Hayes T., Carson D., Bhat S., Van Der Have J., Anderson C., Bissett I., Windsor J., Elliott B. M., Scowcroft H., McLauchlan J., Ritchie D., Jeffery F., Connor S., Xu W., Mashlan H., Thirayan V., Ly J., McGuinness M. J., Ferguson L., Watt I., Harmston C., Akinmade A., Enoch E., Kayode-Nissi V., Ogundele I., Ayoade B. A., Adekoya A., Nwokoro C., Opadeyi A., Yusuf A., Ojajuni A., Adepoju O., Muhammad Dauda M., Keffi Mubarak M., Lawal K., Muhammad D., Salonga D., Sael N. A., Rey C. M., Pestano M., Tan D., Bangayan N. R., Sy D. K., Ang D., Bernardo E., Chua J. P., Alharthi M., Bukhari W., Bakier Mohammed K., Al Athath S., Ghunaim M., Saiedi H., Sultan N., Farsi A., Basendowah M., Malibary N., Jaloun H., Altalhi D., Organjee A., Moamena M., Al Zaidi T. M., Alyami M., Alqannas M., Al-Urfan M., Elawad A., Alawadhi A., Alalawi Y., Alqarni A., Alqahtani B., Alayed A., Alsobaie K., Adi H., Elhaj M., Dehlawi A., Behairy G., Khaled I., Kmezic S., Radenkovic D., Aleksic L., Markovic V., Pejovic I., Antic A., Kalkan M., Vujanovic Gadjanski O., Dusan S., Marcetic B., Thiruchelvam N., Chiow A. K. H., Lee L. S., Mun D. Y. C., Tan E. K., Koh Y. X., Loh W. L., Wang Z., Chan C. Y., Kloppers C., Almgla N., Bernon M., Kahn M., Karimbocus N., Roldan Villavicencio J. I., Goitia V., Gutierrez Rios R. 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Z., Mutlu A.U., Bilgin I.A., Karahasanoglu T., Hamzaoglu I., Bozkirli B., Uprak T.K., Kotan T., Coskun M., Kara Y., Somuncu E., Kocatas A., Bozkurt M.A., Demirli Atici S., Kaya T., Sert I., Emiroglu M., Jaffar M., Younis M.U., Aziz T., Ikram F., Sandal M., Al Madhloum Al Suwaidi F., Alshaikh M.O., Saber A., Khammas A., Nessa A., Jardine R., Nicol L., Clark C., McGee A., Alkari B., Feretis M., Antakia R., Georgiades F., Moneim J., O'Neill R., Balakrishnan A., Lunevicius R., Sud A., Moutsos I., Gomez D., Shahid S., Majeed T., Ibrahim W.K.G., Kadum K., Melia R., Magee C., Chicken D.W., Kumar S., Alshibshoubi M., Van Laarhoven S., Dewi F., Williams J., Byrne B., Wilkerson P., Tang C.B., Farhangmehr N., Jonas A., Charavanamuttu V., Almeida K., Efthimiou E., Boardley J., White A., Butt M.A., Menzies D., Gundkalli Z., Hassanzadeh-Baboli D., Jones O., Mistry P., Saha S., Gerrard A., Evans J., Rajeev S., Ali W., Ross E., Gilliam A., Hitchins C., Emslie K., Spellar K., Sked H., Briggs C., Brown L., A Hemadasa N., Apollos J.R., Belgaumkar A., Tawfik A., Brewin L., Oyewole B., Wadhawan H., Massie E., Rutherford D., McGivern K., McElroy L., De'Ath H.D., Tobbal M., Nagendram S., Patel P., Handa S., Houghton G., Sundaralingam S.S., Parker J., Morgan R., Gala T., Ibrahim S., Harby R., Abdelkarim M., Holroyd D., Thomas R., McLennan E., Boardley R., Jamieson N.B., Ebied H., Gossage J., Davies A., Wheatstone S., Jawad Z., Jiao L., Rajagopal P., Sodergren M., Lami M., Wiberg A., Bond-Smith G., Gemmill E., Lenzi E., Sapre D., Herrod P., Boyd-Carson H., Garcea G., Issa E., Jackson A., Fashina T., Pan H., Farquharson B., Shafiq H., Emanuel O., Mahdi S., Jeyarajah S., Finch L., Whiting G., Pigott L., Martin J., Siriwardena A.K., Beatson K., Abawi L., Lam W., Rea W., Andrews B., Al-Sarireh B., Soliman F., Burridge J., Jenvey C., Hammoda M., Hollyman M., Merker L., Richards J., Sukumaran V., Rogers S., Payne C., Bibi S., Raza K., Ul Ain N., Dronamraju S., Patil S., Nachimuthu S., Ravindran 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M, Cockbain, A, Peckham-Cooper, A, Mccauley, G, Gordon, C, Smith, A, Hawkins, W, Chakravartty, S, Baillie, C, Kenny, R, Kumar, A, Koimtzis, G, Bellamy, E, Menon, A, Kanakala, A, Nevins, E, Madhavan, A, Thulasiraman, S, France, K, O'Connor, A, Idama, D, Raslan, C, Sridhar, S, Parveen, M, Mubashar, T, Jarvis, S, Cakmak, I, Wright, C, Andrews, S, Abdelsaid K Abdul Aal, Y, Jayasankar, B, Morilla, J, Shehata, M, Subba, N, Tewari, N, El-Sayed, C, Somaie, D, Beheiry, N, Douka, E, Arumugam, S, Wijetunga, I, Leivers, E, Ibrahim, B, Khan, K, Wheat, J, Christopher, J, Barnett, R, Elberm, H, Booker, J, Ashai, S, Berry, D, Luhmann, A, Sgro, A, Galea, M, Jeyakumar, J, Marriott, P, Zafar, S, Baker, A, Yershov, D, Galanopoulos, G, Jordan, R, Peinado Garcia, C, Anyaugo, N, Bath, M, Omatseye, J, Roberts, L, Argyriou, E, Machesney, M, Parmar, C, Clark, S, Khalil, H, Unsworth, S, Mlotshwa, M, Ayoub, N, Aboelkhair, A, Iosif, E, Mohamed, N, Reynolds, E, Mackender, E, Robinson, D, Mufti, W, Fischkoff, K, 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S., Radenkovic, D., Aleksic, L., Markovic, V., Pejovic, I., Antic, A., Kalkan, M., Vujanovic Gadjanski, O., Dusan, S., Marčetić, B., Thiruchelvam, N., Chiow, Akh, Lee, L S, Mun, Dyc, Tan, E K, Koh, Y X, Loh, W L, Wang, Z., Chan, C Y, Ibrahim, M., Hamid, Hks, Idres, R., Idris, M., Mohammed, O., Ayran, S., Sinan, A H, Ozben, V., Aytac, E., Aliyeva, Z., Mutlu, A U, Bilgin, I A, Karahasanoglu, T., Hamzaoglu, I., Bozkirli, B., Uprak, T K, Kotan, T., Coskun, M., Kara, Y., Somuncu, E., Kocatas, A., Bozkurt, M A, Demirli Atici, S., Kaya, T., Sert, I., Emiroglu, M., Jaffar, M., Younis, M U, Aziz, T., Ikram, F., Sandal, M., Al Madhloum Al Suwaidi, F., Alshaikh, M O, Saber, A., Khammas, A., Nessa, A., Jardine, R., Nicol, L., Clark, C., Mcgee, A., Alkari, B., Feretis, M., Antakia, R., Georgiades, F., Moneim, J., O'Neill, R., Balakrishnan, A., Lunevicius, R., Sud, A., Moutsos, I., Gomez, D., Shahid, S., Majeed, T., Ibrahim, Wkg, Kadum, K., Melia, R., Magee, C., Chicken, D W, Kumar, S., Alshibshoubi, M., van Laarhoven, S., Dewi, F., Williams, J., Byrne, B., Wilkerson, P., Tang, C B, Farhangmehr, N., Jonas, A., Charavanamuttu, V., Almeida, K., Efthimiou, E., Boardley, J., White, A., Butt, M A, Menzies, D., Gundkalli, Z., Hassanzadeh-Baboli, D., Jones, O., Mistry, P., Saha, S., Gerrard, A., Evans, J., Rajeev, S., Ali, W., Ross, E., Gilliam, A., Hitchins, C., Emslie, K., Spellar, K., Sked, H., Briggs, C., Brown, L., A Hemadasa, N., Apollos, J R, Belgaumkar, A., Tawfik, A., Brewin, L., Oyewole, B., Wadhawan, H., Massie, E., Rutherford, D., Mcgivern, K., Mcelroy, L., De'Ath, H D, Tobbal, M., Nagendram, S., Patel, P., Handa, S., Houghton, G., Sundaralingam, S S, Parker, J., Morgan, R., Gala, T., Ibrahim, S., Mithany, R., Abdelkarim, M., Holroyd, D., Thomas, R., Mclennan, E., Boardley, R., Jamieson, N B, Ebied, H., Gossage, J., Davies, A., Wheatstone, S., Jawad, Z., Jiao, L., Rajagopal, P., Sodergren, M., Lami, M., Wiberg, A., Bond-Smith, G., Gemmill, E., Lenzi, E., Sapre, D., Herrod, P., Boyd-Carson, H., Garcea, G., Issa, E., Jackson, A., Fashina, T., Pan, H., Farquharson, B., Shafiq, H., Emanuel, O., Mahdi, S., Jeyarajah, S., Finch, L., Whiting, G., Pigott, L., Martin, J., Siriwardena, A., Beatson, K., Abawi, L., Lam, W., Rea, W., Andrews, B., Al-Sarireh, B., Soliman, F., Burridge, J., Jenvey, C., Hammoda, M., Hollyman, M., Merker, L., Richards, J., Sukumaran, V., Rogers, S., Payne, C., Bibi, S., Raza, K., Ul Ain, N., Dronamraju, S., Patil, S., Nachimuthu, S., Ravindran, S., Patel, S., Ivanov, B., Patel, M., Ejtehadi, F., Jebamani, J., Akhter Rahman, M M, Woodun, H., De Prendergast, A., Afzal, A., Bota, E., Abdul, S R, Karmarkar, R., Crockett, E., Evans, L., Appleton, B., Griffiths, E., Dada, O., Kulkarni, R., Albirnawi, H., Gravestock, P., Vincenti, C., Taribagil, S., Dent, B., Tse, C., Clayton, B., Burdekin, E., Bannister, L., Alam, I., Gray, J., Mactier, M., Pollock, A., Gough, V., Kanchustambam, S R, Ridgway, M., Arujunan, K., Gopalswamy, S., Monteiro De Barros, J., Lyons, T., Griffith, D., Awan, A K, Latif, J., Bandlamudi, N., Bhatti, I., Raptis, D A, Machairas, N., Pissanou, T., Mestre-Costa, J., Hidalgo Salinas, C., Pollok, J M, Al-Ardah, M., Watson-Jones, E., Rontree-Carey, T., Boyce, T., Hawkin, P., Elmaradny, A., Ross, K., Adu-Peprah, E., Pinto, K., Dunne, D., Mccready, R., Nita, G., Szatmary, P., Tay, V L, Rajput, K., Rajendran, I., Chaudhury, M., Zambas, G., Swaminathan, C., Atif, Qaa, Barrow, T., Williams, O., Malik, A., Conroy, S., Lindley, S., Gilmore, K., Boden, E., Richards, S K, Hraishawi, I., Polak, P., Mclaughlin, D., Deeny, D., Shuttleworth, R., Harris, A., Peilober-Richardson, A., Morris, G C, Sara, X., Almourad, H., Ang, Y., Smyth, R., Ding, D., Foster, J., Bond, A., Kumar, Y., Ahmad, A., Radoi, D., Alkaili-Alyamani, A., Balakrishnan, S., Satchidanand, R Y, Danwaththa Liyanage, A S, Blake, I., Ransome, M., Weerasinghe, C., Kenington, C., Mayo, K., Mohammed, M., Cockbain, A J, Peckham-Cooper, A., Mccauley, G., Gordon, C., Smith, A., Hawkins, W., Chakravartty, S., Baillie, C., Kenny, R., Kumar, A., Koimtzis, G., Bellamy, E., Menon, A., Kanakala, A., Nevins, E J, Madhavan, A., Thulasiraman, S., France, K., O'Connor, A., Idama, D., Raslan, C., Sridhar, S., Parveen, M., Mubashar, T., Jarvis, S., Cakmak, I., Wright, C., Andrews, S., Abdelsaid K Abdul Aal, Y., Jayasankar, B., Morilla, J., Shehata, M., Subba, N., Tewari, N., El-Sayed, C., Somaie, D., Beheiry, N., Douka, E., Arumugam, S., Wijetunga, I., Leivers, E., Ibrahim, B., Khan, K., Wheat, J., Christopher, J., Barnett, R., Elberm, H., Booker, J., Ashai, S., Berry, D., Luhmann, A., Sgro, A., Rashid, M M, Galea, M., Jeyakumar, J., Marriott, P., Zafar, S., Baker, A., Yershov, D., Galanopoulos, G., Jordan, R., Peinado Garcia, C., Anyaugo, N., Bath, M F, Omatseye, J., Roberts, L., Argyriou, E O, Machesney, M., Parmar, C., Clark, S., Khalil, H., Unsworth, S., Mlotshwa, M., Ayoub, N., Aboelkhair, A., Iosif, E., Mohamed, N., Reynolds, E., Mackender, E., Robinson, D., Mufti, W., Fischkoff, K., Coleman, N., Anantha Sathyanarayana, S., Deutsch, G., Giangola, M., Lin, D., Weiss, M., Chung, C., Nguyen, A., Mueller, J., Dabit, M., Gordon, J., McGuire, E., Rashid, O., Georgi, E., Gallo, M., Kunstman, J W, Peters, N V, O'Connor, R., Bhattacharya, B., Onkendi, E., Santos, A P, Richmond, R., Warren, M., Zhang, K., Broderick, R., Clary, B., Horgan, S., Doucet, J., Liepert, A., Harmon, L., McCall, C., Sham, J G, Williams, E., Labadie, K P, Clark, N M, Dickerson, L K, Hammill, C W, Williams, G., Kushner, B., Cos, H., Zarate Rodriguez, J., Bailey, K., Al-Raimi, Imn, Al-Zazay, K., Ahmed Mohammed Al-Mahdi, S., Mohammed Aldowbli, S., Al-Shehari, M., Shream, S., Al-Ameri, S., Aeed, M., Aldawbali, M., Alsayadi, R., and Alsayadi, M.
- Subjects
Pandemic ,SARS-CoV-2 ,acute cholecystitis ,COVID-19 ,management ,Cholecystitis, Acute ,acute ,General Medicine ,pandemics ,cholecystectomy ,humans ,cholecystitis ,Cholecystectomy ,Humans ,Pandemics ,Settore MED/18 - Chirurgia Generale ,Human - Abstract
Background This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic.
- Published
- 2022
7. Konfliktmatrix: Instrument des Risikomanagements im Operationssaal
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Andel, D., Markstaller, K., and Andel, H.
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- 2017
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8. Peritumor Lymphatics in Post-‘radiation Lobectomy’ Livers Are Dysfunctional
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Andel, D., primary, van den Bent, L., additional, Lam, M.G.E.H., additional, Smits, M.L.J., additional, de Bruijne, J., additional, Lacle, M.M., additional, Kranenburg, O.W., additional, Rinkes, I.H.M. Borel, additional, and Hagendoorn, J., additional
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- 2023
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9. Art und Umfang der Anästhesierisikoaufklärung: Auswertung einer Befragung aller Gerichtssachverständigen in Österreich
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Andel, D., Röder, G., Markstaller, K., and Andel, H.
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- 2015
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10. Molecular Methodology for Tick Speciation and Tickborne Pathogen Surveillance
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Green, E., primary, Chase, A., additional, Robinson, M., additional, Callagy, S., additional, Lundstedt, C., additional, Dykstra, L., additional, Van Andel, D., additional, Noyes, C., additional, Rostama, B., additional, Miller, W., additional, and May, M., additional
- Published
- 2022
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11. Cancer Cells that Survive Radiation Lobectomy Display Markers of Increased Tumor Aggressiveness
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Andel, D., primary, Alsultan, A., additional, Peters, N., additional, Laclé, M., additional, Lam, M., additional, Kranenburg, O., additional, Hagendoorn, J., additional, and Rinkes, I. Borel, additional
- Published
- 2022
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12. Laser Spectroscopy of Neutron-Rich Hg 207 , 208 Isotopes: Illuminating
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T. Day Goodacre, A. V. Afanasjev, A. E. Barzakh, B. A. Marsh, S. Sels, P. Ring, H. Nakada, A. N. Andreyev, P. Van Duppen, N. A. Althubiti, B. Andel, D. Atanasov, J. Billowes, K. Blaum, T. E. Cocolios, J. G. Cubiss, G. J. Farooq-Smith, D. V. Fedorov, V. N. Fedosseev, K. T. Flanagan, L. P. Gaffney, L. Ghys, M. Huyse, S. Kreim, D. Lunney, K. M. Lynch, V. Manea, Y. Martinez P
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- 2021
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13. Base deficit and lactate: Early predictors of morbidity and mortality in patients with burns
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Andel, D., Kamolz, L.-P., Roka, J., Schramm, W., Zimpfer, M., Frey, M., and Andel, H.
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- 2007
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14. Antithrombin deficiency and its relationship to severe burns
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Niedermayr, M., Schramm, W., Kamolz, L., Andel, D., Römer, W., Hoerauf, K., Zimpfer, M., and Andel, H.
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- 2007
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15. P.130 Bumetanide versus placebo for core symptoms of autism spectrum disorder at 91 days (BAMBI): a single-centre, double-blinded, patient-randomized, placebo-controlled, phase-2-trial
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Sprengers, J., primary, Van Andel, D., additional, Zuithoff, N., additional, Keijzer-Veen, M., additional, Annelien, S., additional, Scheepers, F., additional, Lilien, M., additional, Oranje, B., additional, and Bruining, H., additional
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- 2020
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16. Surgical outcomes of major hepatectomy following “radiation lobectomy” for hepatic malignancies and insufficiently functional future liver remnant: initial experience
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Andel, D, primary, Dassen, M G, additional, Reinders-Hut, M T M, additional, Peters, N A, additional, Kranenburg, O W, additional, Lam, M G E H, additional, Hagendoorn, J, additional, and Rinkes, I H M Borel, additional
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- 2020
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17. Surgical outcomes of major hepatectomy following 'radiation lobectomy' for hepatic malignancies and insufficiently functional future liver remnant: initial experience
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Lab Translational Oncology, MS CGO, Cancer Center, Cancer, Researchgr. Nucleaire Geneeskunde, Regenerative Medicine and Stem Cells, Andel, D, Dassen, M G, Reinders-Hut, M T M, Peters, N A, Kranenburg, O W, Lam, M G E H, Hagendoorn, J, Rinkes, I H M Borel, Lab Translational Oncology, MS CGO, Cancer Center, Cancer, Researchgr. Nucleaire Geneeskunde, Regenerative Medicine and Stem Cells, Andel, D, Dassen, M G, Reinders-Hut, M T M, Peters, N A, Kranenburg, O W, Lam, M G E H, Hagendoorn, J, and Rinkes, I H M Borel
- Published
- 2020
18. Outcomes of intended chemotherapy treatment of patients with pancreatic adenocarcinoma treated at a tertiary hospital
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Andel, D., primary, Kotze, U., additional, Bernon, M., additional, Kloppers, C., additional, Burmeister, S., additional, and Jonas, E., additional
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- 2020
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19. Hyperbaric oxygen therapy in osteomyelitis
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Andel, H., Felfernig, M., Andel, D., Blaicher, W., and Schramm, W.
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- 1998
20. Time-management in the operating-room
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Andel, H., Wagner, H., Felfernig, M., Andel, D., Schramm, W., and Zimpfer, M.
- Published
- 1998
21. SPLANCHNIC PERFUSION DURING DELIBERATE HYPOTENSION WITH ISOFLURANE
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Andel, D., Schramm, W., Andel, H., and Zimpfer, M.
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- 1997
22. DELAYED EMERGENCE IN PATIENTS AFTER TOTAL INTRA-VENOUS ANAESTHESIA WITH KETAMINE / PROPOFOL
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Blaicher, A M, Blaicher, W, Felfernig, M, Andel, D, Sladen, R N, and Andel, H
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- 1997
23. NECESSARY PROPOFOL DOSE FOR ENDOTRACHEAL INTUBATION WITHOUT NEUROMUSCULAR BLOCKING
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Andel, D, Klune, G, Krafft, P, Schramm, W, Andel, H, and Zimpfer, M.
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- 1997
24. MINIMAL PROPOFOL DOSE FOR FIBRESCOPIC ENDOTRACHEAL INTUBATION WITHOUT RELAXATION
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Klune, G, Andel, D, Schramm, W, Krafft, P, Andel, H, and Zimpfer, M
- Published
- 1997
25. Impact of early high caloric duodenal feeding on the oxygen balance of the splanchnic region after severe burn injury
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Andel, H, Rab, M, Andel, D, Felfernig, M, Hörauf, K, Felfernig, D, Schramm, W, and Zimpfer, M
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- 2001
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26. The axillary vein central venous catheter in severely burned patients
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Andel, H, Rab, M, Felfernig, M, Andel, D, Koller, R, Kamolz, L-P, and Zimpfer, M
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- 1999
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27. Konfliktmatrix
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Andel, D., primary, Markstaller, K., additional, and Andel, H., additional
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- 2017
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28. The Influence of Deliberate Hypotension on Splanchnic Perfusion Balance with Use of Either Isoflurane or Esmolol and Nitroglycerin
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Harald Andel, Michael Zimpfer, Millesi W, Klaus Hörauf, Andel D, and D Felfernig
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Adult ,Vasodilator Agents ,Adrenergic beta-Antagonists ,Oral Surgical Procedures ,Hemodynamics ,Hypotension, Controlled ,Propanolamines ,Nitroglycerin ,medicine ,Humans ,Splanchnic Circulation ,Isoflurane ,business.industry ,Carbon Dioxide ,Hydrogen-Ion Concentration ,Esmolol ,Anesthesiology and Pain Medicine ,Anesthesia ,Anesthetics, Inhalation ,Midazolam ,Arterial blood ,Splanchnic ,Propofol ,business ,Perfusion ,medicine.drug - Abstract
UNLABELLED Various techniques to induce deliberate hypotension (DH) have different influences on splanchnic perfusion. The aim of our study was to determine whether splanchnic perfusion is clinically impaired during DH by using either isoflurane (ISO) or a combination of esmolol and nitroglycerin (E/N). We randomized 16 patients undergoing elective maxillofacial surgery to receive either ISO (0.7%-1.8%) or E (105 g x kg(-1) x min(-1)) and N (1-6 mg/h) to induce DH. General anesthesia was performed in both groups by IV midazolam 0.07 mg/kg, fentanyl 0.003 mg/kg, propofol 1.5 mg/kg, and vecuronium 0.1 mg/kg followed by a propofol infusion with 6 mg x kg(-1) x h(-1). After the induction of anesthesia, a gastric tonometer (TRIP NGS Catheter) and a radial artery catheter were inserted. Baseline values of gastric intramucosal pH (pHi) were determined 60 min after placement of the catheter and before the induction of DH. The pHi values were calculated every 60 min until DH was discontinued. In both groups, DH was satisfactorily established. None of the pHi values calculated was less than 7.37 in the E/N or 7.41 in the ISO group. Arterial blood lactate levels did not increase in any of the patients. We conclude that neither method of producing DH compromises splanchnic tissue oxygen balance in healthy patients. Furthermore, overall organ perfusion was sufficient in both groups, because none of the patients showed an increase in blood lactate. IMPLICATIONS Neither the isoflurane nor the esmolol/nitroglycerin method of producing deliberate hypotension compromises splanchnic tissue oxygen balance in healthy patients. Furthermore, overall organ perfusion was sufficient in both groups, because none of the patients showed an increase in blood lactate.
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- 2001
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29. Treatment of diving-accidents with oxygen under hyperbaric conditions (HBO)
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Andel, H, Andel, D, Kamolz, LP, Schramm, W, and Markstaller, K
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ddc: 610 ,610 Medical sciences ,Medicine ,human activities - Abstract
Introduction: Although diving-accidents may occur during all phases of a dive (descent, isobaric stage, ascent) the main course of accidents is during ascent due to the development of nitrogen bubbles (DCS) or arterial embolization of air (AGE). As DCS and AGE have very similar symptoms, summarized [for full text, please go to the a.m. URL], 7th EFSMA – European Congress of Sports Medicine, 3rd Central European Congress of Physical Medicine and Rehabilitation
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- 2011
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30. The 5-HT2A/1A agonist psilocybin disrupts modal object completion associated with visual hallucinations
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Kometer, M, Cahn, B R, Andel, D, Carter, O L, Vollenweider, F X, University of Zurich, and Kometer, M
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10054 Clinic for Psychiatry, Psychotherapy, and Psychosomatics ,610 Medicine & health ,2803 Biological Psychiatry - Published
- 2011
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31. Atemwegsmanagement des schwer Brandverletzten - das Wiener Konzept
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Andel, D, Kamolz, LP, Römer, W, Brenner, L, Ortner, C, and Andel, H
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ddc: 610 - Published
- 2008
32. Sauerstoff als Medikament und seine Bedeutung für die Wundheilung
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Andel, H., primary, Kamolz, L., additional, Andel, D., additional, Brenner, L., additional, Frey, M., additional, and Zimpfer, M., additional
- Published
- 2007
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33. WHO Guidelines for Pain Management as a New Concept of Analgesia in Severely Burned Patients
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Andel, D., primary, Greher, M., additional, Kamolz, L. P., additional, Andel, H., additional, and Zimpfer, M., additional
- Published
- 2002
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34. The Influence of Deliberate Hypotension on Splanchnic Perfusion Balance with Use of Either Isoflurane or Esmolol and Nitroglycerin
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Andel, D., primary, Andel, H., additional, Hörauf, K., additional, Felfernig, D., additional, Millesi, W., additional, and Zimpfer, M., additional
- Published
- 2001
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35. CENTRAL VENOUS APPROACH VIA VENA AXILLARIS IN CRITICALLY BURNED PATIENTS
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Andel, H., primary, Koller, R., additional, Andel, D., additional, Blaicher, A., additional, and Zimpfer, M., additional
- Published
- 1998
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36. REMIFENTANYL IN THE TREATMENT OF CRITICALLY BURNED PATIENTS
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Andel, D., primary, Koller, R., additional, Felfernig, M., additional, Kapral, S., additional, and Andel, H., additional
- Published
- 1998
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37. A999 INFLUENCE OF DELIBERATE HYPOTENSION ON SPLANCHNIC PERFUSION
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Andel, D., primary, Tonczar, &NA;, additional, Zimpfer M., &NA;, additional, and Andel, H., additional
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- 1997
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38. Which of the abbreviated burn severity index variables are having impact on the hospital length of stay?
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Andel D, Kamolz LP, Niedermayr M, Hoerauf K, Schramm W, Andel H, Andel, Dorothea, Kamolz, Lars-Peter, Niedermayr, Monika, Hoerauf, Klaus, Schramm, Wolfgang, and Andel, Harald
- Published
- 2007
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39. Impact of duodenal feeding on the oxygen balance of the splanchnic region during different phases of severe burn injury.
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Andel H, Rab M, Andel D, Hörauf K, Felfernig D, Schramm W, Zimpfer M, Andel, Harald, Rab, Matthias, Andel, Dorothea, Horauf, Klaus, Felfernig, Dagmar, Schramm, Wolfgang, and Zimpfer, Michael
- Abstract
Enteral nutrition is recommended in burned patients. Depending on the amount administered, enteral feeding causes an increase of intestinal oxygen-demand. Since intestinal perfusion is decreased after major burns the aim of this study was to evaluate, whether duodenal feeding might be a cofactor for the development of a splanchnic O(2)-imbalance. In 15 severely burned patients during duodenal feeding starting within 6 h after injury the assessment of the CO(2)-gap between arterial and gastric CO(2), as a parameter for the measurement of intestinal O(2)-balance was performed. Beginning prior to enteral nutrition CO(2)-gap measurements were carried out to show when the CO(2)-gap increased above 30 mmHg during the whole critical illness phase of the patients. When the CO(2)-gap increased above 30 mmHg enteral nutrition was reduced by 50% and the CO(2)-gap was measured 1 h later. In none of the patients the CO(2)-gap increased during increase of enteral nutrition. In seven patients, the CO(2)-gap increased between the 6th and 13th day above 30 mmHg and fell significantly 1 h after reduction of enteral nutrition. Contrary to the early postburn phase, enteral feeding might have adverse effects on the oxygen balance of the intestine in the later stages of the critical illness phase. [ABSTRACT FROM AUTHOR]
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- 2002
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40. MT46 Patient Experience and Outcomes with Post-Surgical Remote Monitoring for Patients with Total Knee Arthroplasty (TKA).
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Parikh, N, Redfern, R, Yocum, D, Andel D, Van, and Yergler, J
- Published
- 2024
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41. Completion of Patient-Reported Outcome Measures Improved With Use of a Mobile Application in Arthroplasty Patients: Results From a Randomized Controlled Trial.
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Miller MD, Redfern RE, Anderson MB, Abshagen S, Van Andel D, and Lonner JH
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- Humans, Female, Male, Middle Aged, Aged, Smartphone, Patient Compliance, Osteoarthritis, Hip surgery, Patient Reported Outcome Measures, Mobile Applications, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Abstract
Background: The collection of patient-reported outcome measures (PROMs) has historically been reported as costly and time-consuming, with low compliance rates that may impact reimbursement. Little research has reported the effects of mobile applications to support PROMs collection following arthroplasty., Methods: Secondary analysis of data from a multicenter randomized controlled trial was performed. Patients undergoing knee and hip arthroplasty were randomized to utilize a smartphone-based care management platform (app) for self-directed rehabilitation and completed joint-specific PROMs (Hip Dysfunction and Osteoarthritis Outcome Score, Joint Replacement or Knee Injury and Osteoarthritis Score, Joint Replacement) via the application at prescribed intervals or on paper during clinic visits. Control patients received practice standard of care, and completed PROMs via emailed hyperlink or during clinic visits following lower limb arthroplasty. Overall, 455 patients underwent knee arthroplasty procedures (245 control, 210 app group) and 380 underwent total hip arthroplasty (206 control, 174 app group). Compliance with expected PROMs completion was calculated through one year postoperatively., Results: Compliance was higher in the app group preoperatively in both knee (98.1 versus 86.9%, P < .0001) and hip cohorts (96.0 versus 88.4%, P = .008), and postoperatively, including at one year (knees, 72.2 versus 53.7%, P < .0001; hips, 71.1 versus 49.2%, P < .0001). On log-binomial regressions, intervention arm was the strongest predictor of completion of all PROMs, where app users undergoing knee (Relative Risk 2.039, 95% confidence interval (CI) 1.595 to 2.607, P < .000) and hip arthroplasty (2.268 95% CI 1.742 to 2.953, P < .0001) were more likely to be compliant at all timepoints. The majority of patients in the app group, including those over 65 years of age, completed PROMs using the application as opposed to paper methods., Conclusions: A smartphone mobile application that engages patients during recovery after knee and hip joint arthroplasty improved compliance with completion of preoperative and postoperative PROMs compared to other electronic and paper methods., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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42. Patient satisfaction and patient-reported outcomes do not vary by BMI class in total hip arthroplasty.
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Huffman N, Pasqualini I, Redfern RE, Murray TG, Deren ME, Israelite CL, Nelson CL, Van Andel D, Cholewa JM, Anderson MB, Klika AK, McLaughlin JP, and Piuzzi NS
- Subjects
- Humans, Male, Female, Middle Aged, Prospective Studies, Aged, Obesity complications, Pain, Postoperative etiology, Pain Measurement, Arthroplasty, Replacement, Hip adverse effects, Body Mass Index, Patient Satisfaction, Patient Reported Outcome Measures, Osteoarthritis, Hip surgery
- Abstract
Purpose: Obesity has been identified as a risk factor for postoperative complications in patients undergoing total hip arthroplasty (THA). This study aimed to investigate patient-reported outcomes, pain, and satisfaction as a function of body mass index (BMI) class in patients undergoing THA., Methods: 1736 patients within a prospective observational study were categorized into BMI classes. Pre- and postoperative Hip disability and Osteoarthritis Outcome Score for Joint Replacement (HOOS JR), satisfaction, and pain scores were compared by BMI class using one-way ANOVA., Results: Healthy weight patients reported the highest preoperative HOOS JR (56.66 ± 13.35) compared to 45.51 ± 14.45 in Class III subjects. Healthy weight and Class III patients reported the lowest (5.65 ± 2.01) and highest (7.06 ± 1.98, p < 0.0001) preoperative pain, respectively. Changes in HOOS JR scores from baseline suggest larger improvements with increasing BMI class, where Class III patients reported an increase of 33.7 ± 15.6 points at 90 days compared to 26.1 ± 17.1 in healthy weight individuals (p = 0.002). Fewer healthy weight patients achieved the minimal clinically important difference (87.4%) for HOOS JR compared to Class II (96.5%) and III (94.7%) obesity groups at 90 days postoperatively. Changes in satisfaction and pain scores were largest in the Class III patients. Overall, no functional outcomes varied by BMI class postoperatively., Conclusion: Patients of higher BMI class reported greater improvements following THA. While risk/benefit shared decision-making remains a personalized requirement of THA, this study highlights that utilization of BMI cutoff may not be warranted based on pain and functional improvement., (© 2024. The Author(s).)
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- 2024
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43. Pre-existing subclones determine radioresistance in rectal cancer organoids.
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Andel D, Viergever BJ, Peters NA, Elisabeth Raats DA, Schenning-van Schelven SJ, Willem Intven MP, Zandvliet M, Hagendoorn J, Max Borel Rinkes IH, and Kranenburg O
- Subjects
- Humans, Cell Line, Chromosomal Instability, Karyotype, Organoids, Rectal Neoplasms genetics, Rectal Neoplasms radiotherapy
- Abstract
More than half of all patients with cancer receive radiation therapy, but resistance is commonly observed. Currently, it is unknown whether resistance to radiation therapy is acquired or inherently present. Here, we employed organoids derived from rectal cancer and single-cell whole-genome sequencing to investigate the long-term evolution of subclones in response to radiation. Comparing single-cell whole-genome karyotypes between in-vitro-unirradiated and -irradiated organoids revealed three patterns of subclonal evolution: (1) subclonal persistence, (2) subclonal extinction, and (3) subclonal expansion. Organoids in which subclonal shifts occurred (i.e., expansion or extinction) became more resistant to radiation. Although radioresistant subclones did not share recurrent copy-number alterations that could explain their radioresistance, resistance was associated with reduced chromosomal instability, an association that was also observed in 529 human cancer cell lines. These data suggest that resistance to radiation is inherently present and associated with reduced chromosomal instability., Competing Interests: Declaration of interests The authors declare no competing interests., (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.)
- Published
- 2024
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44. A Retrospective Study on the Feasibility of Using Low-burden Patient-reported Pain Scores to Track Recovery and Outcomes After Total Joint Replacement.
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Surmacz K, Ribeiro-Castro AL, Anderson MB, Van Andel D, Redfern RE, and Duwelius PJ
- Abstract
Background: Patients undergo total joint arthroplasty to improve function and resolve pain. Patient-reported outcome measures (PROMs) are often sought to determine the success of total joint arthroplasty but are time-consuming and patient response rates are often low. This study sought to determine whether pain numeric rating scores (NRSs) were associated with PROMs and objective mobility outcomes., Methods: This is a retrospective review of data in patients who utilized a smartphone-based care management application prior to and following total joint arthroplasty. NRS, Hip Disability and Osteoarthritis Outcome Score, Joint Replacement and Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, and objective mobility data (step counts, gait speed, and gait asymmetry) were collected preoperatively and at 30 and 90 days postoperatively. Quantile regression was performed to evaluate the correlations between NRS and PROMs., Results: Total knee arthroplasty patients reported higher NRS than total hip arthroplasty patients postoperatively. NRS was significantly correlated with gait speed preoperatively and at 30 and 90 days postoperatively on quantile regression. Gait asymmetry was significantly associated with NRS at 30 days postoperatively. Regression results suggested significant correlations between NRS and PROMs scores; Hip Disability and Osteoarthritis Outcome Score, Joint Replacement, -0.46 (95% confidence interval: -0.48 to -0.44, P < .001) and Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, -0.38 (95% confidence interval: -0.40 to -0.36, P < .001)., Conclusions: NRS is correlated with both objective and subjective measures of function in patients undergoing arthroplasty. Simple pain ratings may be a valid measurement to help predict functional outcomes when collection of traditional PROMs is not feasible., (© 2023 The Authors.)
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- 2024
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45. Early post-operative walking bouts are associated with improved gait speed and symmetry at 90 days.
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Ribeiro-Castro AL, Surmacz K, Aguilera-Canon MC, Anderson MB, Van Andel D, Redfern RE, and Cook CE
- Subjects
- Humans, Gait, Walking, Lower Extremity, Walking Speed, Arthroplasty, Replacement, Knee methods
- Abstract
Introduction: There is a paucity of literature on optimal patterns of daily walking following joint arthroplasty, which are now evaluated with consumer technologies like smartphones, and can enhance our understanding of post-operative mobility. When smartphone-recorded, daily walking patterns are captured, qualities of gait-recovery such as gait speed or symmetry can be analyzed in real-world environments., Research Question: Are the daily distribution of walking bouts in the early post-operative period associated with 90-day gait quality measures following hip and knee arthroplasty?, Methods: Gait data was collected passively using a smartphone-based care management platform in patients undergoing hip and knee arthroplasty. As recorded via subjects' free-living smartphone-collected gait bouts, data were investigated as a function of the walking session length and were used to create a ratio to the total time logging bouts, representing the fraction of walking performed during a single session per day (aggregation score). Quantile regression was performed to evaluate the association between early walking session lengths or aggregation score at 30 days post-operatively and the gait-sampled speed and asymmetry of walking at 90 days., Results: In total, 2255 patients provided evaluable data. The walking session length at 30 days was positively associated with 90-day mean gait speed across procedure types where quantile regression coefficients ranged from 0.11 to 0.17. In contrast, aggregation score was negatively associated with gait speed at 90 days, with coefficients ranging from -0.18 to -0.12., Significance: The duration and frequency of walking bouts was associated with recovery of gait speed and symmetry following lower limb arthroplasty. The findings may help clinicians design walking protocols that are associated with improved gait metrics at 3 months., Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Chad Cook – paid consultant, Zimmer Biomet. Alex Ribeiro-Castro – employee of Zimmer Biomet at the time of project. Karl Surmacz – employee of Zimmer Biomet with stock or stock options. Mara Catalina Aguilera-Canon – employee of Zimmer Biomet with stock or stock options. Mike B Anderson – employee of Zimmer Biomet with stock or stock options. Dave Van Andel – employee of Zimmer Biomet with stock or stock options. Roberta Redfern – employee of Zimmer Biomet with stock or stock options., (Copyright © 2023 Elsevier B.V. All rights reserved.)
- Published
- 2024
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46. 90 Y-/ 166 Ho- 'Radiation lobectomy' for liver tumors induces abnormal morphology and impaired drainage of peritumor lymphatics.
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Andel D, van den Bent L, Ernest Hendrik Lam MG, Johannes Smits ML, Molenaar IQ, de Bruijne J, Laclé MM, Kranenburg O, Max Borel Rinkes IH, and Hagendoorn J
- Abstract
Background & Aims: High-dose unilobar radioembolization, or 'radiation lobectomy' (RL), is an induction therapy that achieves contralateral future liver remnant hypertrophy while simultaneously irradiating the tumor. As such, it may prevent further growth, but it is unknown whether RL affects intrahepatic lymphatics, a major route via which liver tumors disseminate., Methods: This was a case-control study conducted at University Medical Center Utrecht. The study compared lymph vessels in livers that had undergone RL (cases) with those in livers that had not undergone RL (controls). Histological samples were acquired from patients diagnosed with hepatocellular carcinoma (HCC) or colorectal liver metastases (CRLM) between 2017 and 2022. Lymph vessel morphology was analyzed by two researchers using podoplanin, a protein that is expressed in lymphatic endothelium. In vivo liver lymph drainage of radioembolized livers was assessed using intraoperative liver lymphangiography (ILL): during liver surgery, patent blue dye was injected into the liver parenchyma, followed by inspection for staining of perihepatic lymph structures. ILL results were compared to a previously published cohort., Results: Immunohistochemical analysis on post-RL tumor tissues from ten patients with CRLM and nine patients with HCC revealed aberrant morphology of irradiated liver lymphatics when compared to controls (n = 3 per group). Irradiated lymphatics were tortuous ( p <0.05), thickened ( p <0.05) and discontinuous ( p <0.05). Moreover, post-RL lymphatics had larger lumens (1.5-1.7x, p <0.0001), indicating lymph stasis. ILL revealed diminished lymphatic drainage to perihepatic lymph nodes and vessels in irradiated livers when compared to non-radioembolized controls ( p = 1.0x10
-4 )., Conclusions: Radioembolization impairs peritumoral lymph vessel function. Further research is needed to evaluate if radioembolization impairs tumor dissemination via this route., Impact and Implications: Unilobar radioembolization can serve as an alternative to portal venous embolization for patients who are considered unresectable due to an insufficient future liver remnant. This research suggests that radioembolization impairs the function of peritumoral liver lymph vessels, potentially hindering dissemination via this route. These findings provide support for considering unilobar radioembolization over standard portal venous embolization., Competing Interests: Marnix Lam is a consultant for Boston Scientific and Terumo. Maarten Smits is consultant for Philips and Terumo/Quierem Medical and has served as speakers for SirTex, BTG, Swedisch Orphan Biovitrum, Terumo and Metronic. The Department of Radiology and Nuclear Medicine of the UMC Utrecht receives royalties from Quirem Medical. No other potential conflict of interest relevant to this article was reported. Please refer to the accompanying ICMJE disclosure forms for further details., (© 2023 The Authors.)- Published
- 2023
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47. Colorectal liver metastases that survive radioembolization display features of aggressive tumor behavior.
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Andel D, Hagendoorn J, Alsultan AA, Lacle MM, Smits MLJ, Braat AJAT, Kranenburg O, Lam MGEH, and Borel Rinkes IHM
- Abstract
Background: Radiation lobectomy is a therapeutic approach that involves targeted radiation delivery to induce future liver remnant hypertrophy and tumor control. In patients with colorectal liver metastases, only 30-40% have complete tumor regression. The importance of tumor biology in treatment response remains elusive., Methods: Patients with colorectal liver metastases who received radiation lobectomy were selected from surgical pathology files. Using a machine learning scoring protocol, pathological response was correlated to tumor absorbed dose and expression of markers of radioresistance Ki-67 (proliferation), CAIX (hypoxia), Olfm4 (cancer stem cells) and CD45 (leukocytes)., Results: No linear association was found between tumor dose and response (ρ < 0.1, P = 0.73 (
90 Y), P = 0.92 (166 Ho)). Response did correlate with proliferation (ρ = 0.56, P = 0.012), and non-responsive lesions had large pools (>15%) of Olfm4 positive cancer stem cells (Fisher's exact test, P = 0.0037). Responding lesions (regression grade ≤2) were highly hypoxic compared to moderate and non-responding lesions (P = 0.011). Non-responsive lesions had more tumor-infiltrating leukocytes (3240 cells/mm2 versus 650 cells/mm2 ), although this difference was not significant (P = 0.08)., Conclusion: The aggressive phenotype of a subset of surviving cancer cells emphasizes the importance of prompt resection after radiation lobectomy., (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)- Published
- 2023
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48. Novel Benchmark Values for Open Major Anatomic Liver Resection in Non-cirrhotic Patients: A Multicentric Study of 44 International Expert Centers.
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Sousa Da Silva RX, Breuer E, Shankar S, Kawakatsu S, Hołówko W, Santos Coelho J, Jeddou H, Sugiura T, Ghallab M, Da Silva D, Watanabe G, Botea F, Sakai N, Addeo P, Tzedakis S, Bartsch F, Balcer K, Lim C, Werey F, Lopez-Lopez V, Peralta Montero L, Sanchez Claria R, Leiting J, Vachharajani N, Hopping E, Torres OJM, Hirano S, Andel D, Hagendoorn J, Psica A, Ravaioli M, Ahn KS, Reese T, Montes LA, Gunasekaran G, Alcázar C, Lim JH, Haroon M, Lu Q, Castaldi A, Orimo T, Moeckli B, Abadía T, Ruffolo L, Dib Hasan J, Ratti F, Kauffmann EF, de Wilde RF, Polak WG, Boggi U, Aldrighetti L, McCormack L, Hernandez-Alejandro R, Serrablo A, Toso C, Taketomi A, Gugenheim J, Dong J, Hanif F, Park JS, Ramia JM, Schwartz M, Ramisch D, De Oliveira ML, Oldhafer KJ, Kang KJ, Cescon M, Lodge P, Rinkes IHMB, Noji T, Thomson JE, Goh SK, Chapman WC, Cleary SP, Pekolj J, Regimbeau JM, Scatton O, Truant S, Lang H, Fuks D, Bachellier P, Ohtsuka M, Popescu I, Hasegawa K, Lesurtel M, Adam R, Cherqui D, Uesaka K, Boudjema K, Pinto-Marques H, Grąt M, Petrowsky H, Ebata T, Prachalias A, Robles-Campos R, and Clavien PA
- Subjects
- Humans, Hepatectomy methods, Benchmarking, Postoperative Complications etiology, Retrospective Studies, Length of Stay, Liver Neoplasms surgery, Liver Neoplasms etiology, Liver Failure etiology, Laparoscopy methods
- Abstract
Objective: This study aims at establishing benchmark values for best achievable outcomes following open major anatomic hepatectomy for liver tumors of all dignities., Background: Outcomes after open major hepatectomies vary widely lacking reference values for comparisons among centers, indications, types of resections, and minimally invasive procedures., Methods: A standard benchmark methodology was used covering consecutive patients, who underwent open major anatomic hepatectomy from 44 high-volume liver centers from 5 continents over a 5-year period (2016-2020). Benchmark cases were low-risk non-cirrhotic patients without significant comorbidities treated in high-volume centers (≥30 major liver resections/year). Benchmark values were set at the 75th percentile of median values of all centers. Minimum follow-up period was 1 year in each patient., Results: Of 8044 patients, 2908 (36%) qualified as benchmark (low-risk) cases. Benchmark cutoffs for all indications include R0 resection ≥78%; liver failure (grade B/C) ≤10%; bile leak (grade B/C) ≤18%; complications ≥grade 3 and CCI ® ≤46% and ≤9 at 3 months, respectively. Benchmark values differed significantly between malignant and benign conditions so that reference values must be adjusted accordingly. Extended right hepatectomy (H1, 4-8 or H4-8) disclosed a higher cutoff for liver failure, while extended left (H1-5,8 or H2-5,8) were associated with higher cutoffs for bile leaks, but had superior oncologic outcomes, when compared to formal left hepatectomy (H1-4 or H2-4). The minimal follow-up for a conclusive outcome evaluation following open anatomic major resection must be 3 months., Conclusion: These new benchmark cutoffs for open major hepatectomy provide a powerful tool to convincingly evaluate other approaches including parenchymal-sparing procedures, laparoscopic/robotic approaches, and alternative treatments, such as ablation therapy, irradiation, or novel chemotherapy regimens., Competing Interests: The authors report no conflicts of interest., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2023
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49. Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol.
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Andel D, Lam MGEH, de Bruijne J, Smits MLJ, Braat AJAT, Moelker A, Vegt E, Ruiter SJS, Noordzij W, Grazi G, Vallati GE, Bennink RJ, van Delden OM, Kranenburg OW, Ijzermans JNM, Nijkamp MW, Erdmann JI, Sciuto R, Hagendoorn J, and Borel Rinkes IHM
- Subjects
- Humans, Microspheres, Prospective Studies, Quality of Life, Hepatomegaly, Multicenter Studies as Topic, Carcinoma, Hepatocellular radiotherapy, Liver Neoplasms radiotherapy
- Abstract
Background: High dose unilobar radioembolization (also termed 'radiation lobectomy')-the transarterial unilobar infusion of radioactive microspheres as a means of controlling tumour growth while concomitantly inducing future liver remnant hypertrophy-has recently gained interest as induction strategy for surgical resection. Prospective studies on the safety and efficacy of the unilobar radioembolization-surgery treatment algorithm are lacking. The RALLY study aims to assess the safety and toxicity profile of holmium-166 unilobar radioembolization in patients with hepatocellular carcinoma ineligible for surgery due to insufficiency of the future liver remnant., Methods: The RALLY study is a multicenter, interventional, non-randomized, open-label, non-comparative safety study. Patients with hepatocellular carcinoma who are considered ineligible for surgery due to insufficiency of the future liver remnant (< 2.7%/min/m
2 on hepatobiliary iminodiacetic acid scan will be included. A classical 3 + 3 dose escalation model will be used, enrolling three to six patients in each cohort. The primary objective is to determine the maximum tolerated treated non-tumourous liver-absorbed dose (cohorts of 50, 60, 70 and 80 Gy). Secondary objectives are to evaluate dose-response relationships, to establish the safety and feasibility of surgical resection following unilobar radioembolization, to assess quality of life, and to generate a biobank., Discussion: This will be the first clinical study to assess the unilobar radioembolization-surgery treatment algorithm and may serve as a stepping stone towards its implementation in routine clinical practice., Trial Registration: Netherlands Trial Register NL8902 , registered on 2020-09-15., (© 2023. BioMed Central Ltd., part of Springer Nature.)- Published
- 2023
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50. Stepping Beyond Counts in Recovery of Total Hip Arthroplasty: A Prospective Study on Passively Collected Gait Metrics.
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Fary C, Cholewa J, Abshagen S, Van Andel D, Ren A, Anderson MB, and Tripuraneni K
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- Humans, Prospective Studies, Walking, Benchmarking, Gait, Arthroplasty, Replacement, Hip
- Abstract
Gait quality parameters have been used to measure recovery from total hip arthroplasty (THA) but are time-intensive and previously could only be performed in a lab. Smartphone sensor data and algorithmic advances presently allow for the passive collection of qualitative gait metrics. The purpose of this prospective study was to observe the recovery of physical function following THA by assessing passively collected pre- and post-operative gait quality metrics. This was a multicenter, prospective cohort study. From six weeks pre-operative through to a minimum 24 weeks post-operative, 612 patients used a digital care management application that collected gait metrics. Average weekly walking speed, step length, timing asymmetry, and double limb support percentage pre- and post-operative values were compared with a paired-sample t -test. Recovery was defined as the post-operative week when the respective gait metric was no longer statistically inferior to the pre-operative value. To control for multiple comparison error, significance was set at p < 0.002. Walking speeds and step length were lowest, and timing asymmetry and double support percentage were greatest at week two post-post-operative ( p < 0.001). Walking speed (1.00 ± 0.14 m/s, p = 0.04), step length (0.58 ± 0.06 m/s, p = 0.02), asymmetry (14.5 ± 19.4%, p = 0.046), and double support percentage (31.6 ± 1.5%, p = 0.0089) recovered at 9, 8, 7, and 10 weeks post-operative, respectively. Walking speed, step length, asymmetry, and double support all recovered beyond pre-operative values at 13, 17, 10, and 18 weeks, respectively ( p < 0.002). Functional recovery following THA can be measured via passively collected gait quality metrics using a digital care management platform. The data suggest that metrics of gait quality are most negatively affected two weeks post-operative; recovery to pre-operative levels occurs at approximately 10 weeks following primary THA, and follows a slower trajectory compared to previously reported step count recovery trajectories.
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- 2023
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