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1. Efficacy and Safety of Inosine Pranobex in COVID‐19 Patients: A Multicenter Phase 3 Randomized Double‐Blind, Placebo‐Controlled Trial

Author

Jayanthi C R, Ashok K Swain, Ranganath T Ganga, Dnyaneshwar Halnor, Ajit Avhad, Mohd. Saif Khan, Ayan Ghosh, Sumer Sanjiv Choudhary, Anand Namdevrao Yannawar, Shubhangi Despande, Manish Patel, Krishna Prasad Anne, and Yogesh Bangar

Subjects
Pharmacology, Biochemistry (medical), Pharmaceutical Science, Medicine (miscellaneous), Pharmacology (medical), Genetics (clinical)
Abstract

Inosine pranobex (IP), an immunomodulatory agent, is used in the treatment of various viral infections. The results of a phase 3 randomized controlled trial are reported, evaluating the efficacy and safety of IP in the treatment of mild to moderate COVID-19. It includes 416 symptomatic patients with confirmed SARS-CoV-2 infection. In addition to a defined standard of care, patients randomly (1:1) receive either IP 500 mg tablet (IP group) or a matching placebo (placebo group) at 50 mg kg

Published
2022
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