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Aim: To evaluate if statistically significant results are more likely to be reported in title/abstracts compared to non-significant outcomes. Methods: In this methodological survey, we reanalyzed 59 observational studies from a previous systematic review. The PECO question was: Patient (P): children with primary teeth; Exposure (E): low birth weight and/or preterm; Comparison (C): normal birth weight and/or full-term; Outcome (O): dental caries. We analyzed the presence of key terms in the titles and abstracts, such as gestational age, preterm, full-term, birth weight, low/normal birth weight. Full texts were analyzed for “positive outcomes” (statistically significant association, p < 0.05 or 95% CI not crossing the null effect line) related to the association between the outcome and the exposure; and “negative outcomes” (when the outcome had statistically similar occurrence between the exposure and the comparison group). The odds ratio (OR) was calculated between the presence of key terms in titles/abstracts and the type of outcome (positive or negative). Results: Of 59 studies, 66% cited the key terms in titles/abstracts, and 75% reported negative outcomes. Studies with positive outcomes were more likely to report key terms in the titles/abstracts compared to studies with negative outcomes (OR: 4.5; 95% CI: 0.9-22.4; Chi-square test: p = 0.06). Studies with statistically significant outcomes, favoring the exposure or the comparison, were more likely to report these data in the titles/abstracts. Conclusion: When conducting a systematic review, the final decision related to the inclusion of a study must be based on a full-text level.

To synthesize the oral alterations observed in children with microcephaly associated with congenital Zika virus syndrome (CZS); and to compare the oral alterations of these children to a normotypic healthy controls.A search was performed in six electronic databases. Observational studies published that reported oral alterations in children with CZS were selected. Two authors independently extracted data, assessed study quality, using the Joanna Briggs Institute Critical Appraisal Checklist tools, and the certainty of evidence, using Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Twenty-one studies were included in this systematic review and meta-analysis. The pooled crude occurrence showed 88% of increased salivation (95%CI: 82%-94%), 83% of biofilm (95%CI: 75%-91%), and 73% of bruxism (95%CI: 52%-95%). Compared to normotypic controls, children with CZS-associated microcephaly had a higher chance to have difficulty in lip sealing (OR: 18.28; 95%CI: 1.42-235.91), inadequate lingual posture at rest (OR: 13.57; 95%CI: 4.24-43.44), and delayed eruption (OR: 12.92; 95%CI: 3.42-48.78), with very low certainty.There are several oral alterations found among children with CZS-associated microcephaly. They are more prone to present some of these alterations, such as difficulty in lip sealing, although with very low certainty of evidence.

Objetivo: Fornecer um guia no formato de checklist para auxiliar pesquisadores na condução de revisões integrativas em Odontologia. Métodos: O guia para revisões integrativas em Odontologia foi construído a partir do Preferred Reporting Items for Systematic Reviews and Meta-Analyses (The PRISMA Statement). Resultados: Para o delineamento de revisões integrativas em Odontologia é preciso percorrer etapas distintas: 1. Identificação do tema (elaboração da pergunta de pesquisa); 2. Estabelecimento dos critérios de elegibilidade de estudos; 3. Busca sistematizada em diversas fontes de informação; 4. Coleta de dados; 5. Análise dos dados; 6. Discussão; 7. Apresentação da revisão/síntese do conhecimento. Os erros mais comuns ao realizar uma revisão integrativa estão relacionados à descrição incompleta ou não realização de etapas importantes, tais como: 1. Processo de seleção das evidências; 2. Estratégia de busca reprodutível; 3. Detalhes relacionados à busca, seleção e inclusão de estudos; 4. Aplicação dos critérios de elegibilidade; 5. Processo de extração dos dados (definição clara dos dados a serem extraídos, número de revisores envolvidos); 6. Apresentação do processo de seleção de estudos no formato de fluxograma; 7. Avaliação da qualidade dos estudos; 8. Síntese dos resultados. Conclusão: O guia para revisões integrativas em Odontologia apresenta utilidade na redução de equívocos metodológicos frequentemente observados nesse desenho de estudo, bem como estimula a condução de trabalhos com delineamentos robustos.

External factors during social distancing caused by the COVID-19 pandemic might have influenced human behavior and impacted the different chronotype’s profiles. This cross-sectional study evaluated...

Evaluate dietary habits and the presence of erosive tooth wear (ETW) among female adolescents with varying severity of bulimic symptomatology. An explanatory study was conducted with 72 female school adolescents with bulimic symptomatology, aged 15–18 years in Southeastern Brazil. Dietary habits were evaluated through a food frequency questionnaire. Bulimic symptomatology was evaluated and classified (mild, moderate and severe) according to the Bulimic Investigatory Test of Edinburgh. ETW examinations were performed. Data analysis involved descriptive statistics, bivariate analysis, Kruskal–Wallis/Mann–Whitney tests and Poisson regression. Ethical approval and informed consents were obtained. The final population consisted of 62 participants. The prevalence of ETW differed among adolescents with mild, moderate and severe bulimic symptomatology (p = 0.001), corresponding to 5.9%, 8.0% and 45.0%, respectively. Adolescents with severe bulimic symptomatology presented higher daily consumption of acidic food: citric fruits (p

Erosive tooth wear (ETW) is defined as a chemical-mechanical process leading to the cumulative loss of hard dental tissue without the involvement of bacteria. The prevalence of ETW has been reported to range from 10% to over 80% in children and 4% to 82% in adults. The management of ETW should include an early diagnosis, the evaluation of different etiological factors, risk identification and the proposal of preventive measures to delay the advance of the condition. These measures include fluoride exposure, use of low abrasive toothpastes, clinical monitoring, and in more severe cases sealant application and restorations. Patients suffering from eating disorders with purging behaviour and gastroesophageal reflux disease are considered the most important group of risk for this condition. Clinicians should be aware of this condition with growing prevalence, once substance loss is an irreversible condition, providing prompt preventive measures, during the early stages, are essential to reduce ETW. Key words: Erosive Tooth Wear, Dental Erosion, Diagnosis, Prevention. O Desgaste Dentário Erosivo é definido como um processo químico-mecânico que leva a uma perda cumulativa de tecido dentário duro, sem que ocorra o envolvimento de bactérias. A prevalência de Desgaste Dentário Erosivo tem sido reportada na literatura em porcentagens que variam de 10% a 80% em crianças e de 4% a 82% em adultos. A abordagem clínica do Desgaste Dentário Erosivo deve incluir um diagnóstico precoce, a avaliação dos diferentes fatores etiológicos, a identificação do risco e a proposta de medidas preventivas para retardar a progressão dessa condição. Essas medidas incluem a aplicação de fluoretos, o uso de dentifrícios com baixa abrasividade, monitoramento clinico e, em casos mais graves, a aplicação de selantes e procedimentos restauradores. Pacientes diagnosticados com transtornos alimentares ou com refluxo gastroesofágico são considerados um dos grupos de risco mais importantes para o desenvolvimento dessa condição. Os clínicos devem estar atentos a essa condição de prevalência crescente, uma vez que a perda de estrutura dentária é irreversível, provovendo medidas preventivas eficazes, desde os estágios iniciais, contribuindo assim para o controle e redução do Desgaste Dentário Erosivo entre seus pacientes. Palavras chave: Desgaste Dentário Erosivo, Erosão Dentária, Diagnóstico, Prevenção.

The aim of this study is to evaluate the effectiveness of two types of oral appliance (OA) in the treatment of severe obstructive sleep apnea syndrome (OSAS) and their impact on the reduction of obstructive, central and mixed apneas. Forty-eight patients suffering from severe OSAS with a history of non-adherence to positive airway pressure therapy were treated with OA (lingual orthosis and combined orthosis). Polysomnography exams were performed before and after treatment. Computed tomography and cephalometric radiography were requested for all patients to evaluate the titrated position of the OA and the airspace obtained. Statistical tests used the Minitab, version 17, program. The level of statistical significance was 5%. Before treatment, the mean AHI was 56.3 ± 19.1 events/h. It decreased to 8.1 ± 5.2 after the OA titration (p ≤ 0.001). There was a significant reduction in obstructive events from 43.0 ± 20.2 to 7.1 ± 4.6 events/h (p ≤ 0.001). The reduction in central events after OA treatment was also significant (from 5.1 ± 9.3 to 0.8 ± 1.9 events/h; p ≤ 0.001), whereas that in mixed events decreased from 6.4 ± 9.5 to 0.1 ± 0.3 events/h (p ≤ 0.001). The minimum oxygen saturation also showed significant improvement after treatment (p ≤ 0.001). There was no statistically significant difference between both OA with respect to central events (p = 0.22) or mixed events (p = 0.98). The treatment was effective in reducing obstructive events which were evaluated through the AHI and minimum oxygen saturation. The oral appliances also normalized central and mixed events among patients with severe OSAS.

Este estudo teve como objetivo avaliar o conhecimento relacionado ao desgaste dentário erosivo entre pacientes, alunos e docentes de uma faculdade de odontologia brasileira, e compará-lo com um estudo anterior, realizado dez anos antes, no mesmo ambiente acadêmico. Trata-se de um estudo transversal controlado, envolvendo 289 participantes, que foi realizado em uma faculdade de odontologia em Belo Horizonte, sudeste do Brasil. O conhecimento do desgaste erosivo foi avaliado por um questionário autoaplicável. A análise estatística utilizou o teste qui-quadrado e teste Z ajustado pela correção de Bonferroni (p0,05). Aprovação ética e consentimento informado foram obtidos. Dentre os 289 participantes, 71,0% já ouviram falar sobre o desgaste dentário erosivo, com menor percentual entre os pacientes (p0,001). Alunos e docentes frequentemente mencionaram transtornos alimentares e dieta ácida como os principais fatores etiológicos para o desgaste erosivo (p0,001). No entanto, os pacientes relataram bactérias (p=0,026) e má higiene bucal (p=0,002) como fatores etiológicos. A comparação entre os resultados atuais e o estudo anterior não mostrou aumento significativo quanto aos participantes que tinham ouvido falar sobre a essa implicação dentária (p0,499). Também não houve melhora no conhecimento do desgaste erosivo entre os pacientes (p0,227), e nenhuma diferença significativa quando eles foram questionados se haviam recebido recomendações preventivas dos alunos (p=0,303). No entanto, houve uma melhora significativa em todas as variáveis em relação às habilidades diagnósticas dos alunos (p0,005) e no conhecimento dos sinais e sintomas do desgaste erosivo entre os docentes (p=0,030). Em conclusão, o conhecimento do desgaste dentário erosivo ainda não está totalmente incorporado pela amostra. No entanto, houve uma melhoria nas habilidades de diagnóstico dos alunos e docentes desde o último estudo, realizado em 2010.

Aim: This study aimed to evaluate the respiratory parameters among patients diagnosed with severe obstructive sleep apnea (OSA) syndrome treated with a novel design of an oral appliance (OA): a lingual orthosis.Methods: A case series study was conducted with 11 patients suffering from severe OSA, apnea-hypopnea index (AHI) > 30 events/h. All patients underwent pre- and post-treatment overnight polysomnography and were diagnosed by a physician based on polysomnography indexes. All selected patients had a history of nonadherence to continuous positive airway pressure devices.Results: Before treatment, the mean AHI of the sample was 65.9 ± 30.5. After reaching the optimal OA titration, the polysomnography (PSG) showed an average AHI of 10.1 ± 5.5 (p

The World Health Organization recommends exclusive breast feeding for at least six months. However, there is no scientific evidence of the benefits of breast feeding for oral health in children under primary dentition. This study aimed to search for scientific evidence regarding the following question: is bottle feeding associated with malocclusion in the primary dentition compared to children that are breastfed? An electronic search was performed in seven databases. The systematic review included 10 cohort studies. It was not possible to conduct meta-analysis, therefore a qualitative analysis was assessed. The majority of studies evaluated feeding habits by means of questionnaires and conducted a single examination. Three studies observed that bottle feeding was significantly associated with overjet and posterior crossbite. Studies reported several cut-off times for breastfeeding (varying from 1 month up to 3 years of age) and several types of malocclusion. Controlling for non-nutritive sucking habits was reported for only half of the studies and this may have led to biased results. The scientific evidence could not confirm a specific type of malocclusion associated with the feeding habits or an adequate time of breastfeeding to benefit the children against malocclusion. Further cohort studies are needed to confirm this evidence.

Assess agreement between proxy respondents (caregivers) and children/adolescents related to the impact of cancer on children’s/adolescents’ health-related quality of life, with respect to anxiety and worry issues. A cross-sectional study was conducted among 83 Brazilian children/adolescents, of both genders, diagnosed with cancer, aged 5–18 years and their proxy respondents. Anxiety and worry were assessed through items of the instrument Pediatric Quality of Life Inventory™ Cancer Module Scale. Participants were recruited from the pediatric hematology/oncology centers at two public hospitals. All individuals were receiving medical care. Descriptive statistics were performed as well as a weighted kappa coefficient, Spearman’s correlation coefficient, Wilcoxon signed-rank test and Bland–Altman plots. The magnitude of the difference between the mean scores obtained from children/adolescents and that of their proxy respondents was evaluated through effect size. The proxy respondents underestimated the feelings of worry among children (8–12 years) (p

BACKGROUND: Dental practitioners have a key role in the quality of life and prevention of occupational accidents of workers with Obstructive Sleep Apnea Syndrome (OSAS). AIM: The aim of this study was to review the impact of OSAS, the Continuous Positive Airway Pressure (CPAP) therapy, and the evidence regarding the use of oral appliances (OA) on the health and safety of workers. MATERIALS AND METHODS: Searches were conducted in MEDLINE (PubMed), Lilacs and Sci ELO. Articles published from January 1980 to June 2014 were included. RESULTS: The research retrieved 2188 articles and 99 met the inclusion criteria. An increase in occupational accidents due to reduced vigilance and attention in snorers and patients with OSAS was observed. Such involvements were related to excessive daytime sleepiness and neurocognitive function impairments. The use of OA are less effective when compared with CPAP, but the results related to excessive sleepiness and cognitive performance showed improvements similar to CPAP. Treatments with OA showed greater patient compliance than the CPAP therapy. CONCLUSION: OSAS is a prevalent disorder among workers, leads to increased risk of occupational accidents, and has a significant impact on the economy. The CPAP therapy reduces the risk of occupational accidents. The OA can improve the work performance; but there is no scientific evidence associating its use with occupational accidents reduction. Future research should focus on determining the cost-effectiveness of OA as well as its influence and efficacy in preventing occupational accidents. Language: en

PURPOSE: To verify the nutritive and non-nutritive stimuli efficacy in the newborn's response to pain during venipuncture. METHODS: The main sample was composed of 64 newborns that were randomly divided into three groups. The first group (n=20) received nutritive sucking stimulus that was performed through maternal breastfeeding. The second group (n=21) received non-nutritive sucking stimulus that was performed through the introduction of the researcher little finger in the newborn's oral cavity. The third group or control group (n=23) did not receive any analgesia stimulus. The newborns were evaluated using the Neonatal Infant Pain Scale, and the responses to painful stimuli were compared. RESULTS: The nutritive as well as non-nutritive suction methods provided a comforting effect, resulting in lower pain response scores (p0.05). CONCLUSION: The nutritive and the non-nutritive sucking stimuli proved to be efficacious tools in relieving pain among newborns. OBJETIVO: Verificar a eficácia dos estímulos de sucção nutritiva e não nutritiva na resposta do recém-nascido à dor durante a punção venosa. MÉTODOS: A amostra principal foi composta por 64 recém-nascidos que foram divididos aleatoriamente em três grupos. O primeiro grupo (n=20) recebeu estímulo de sucção nutritiva, o qual foi realizado através da amamentação materna. O segundo grupo (n=21) recebeu estímulo de sucção não nutritiva, o qual foi realizado através da introdução do dedo mínimo do pesquisador na cavidade oral do recém-nascido. O terceiro grupo ou grupo de controle (n=23) não recebeu qualquer estímulo de analgesia. Os recém-nascidos foram avaliados utilizando a Escala de Dor do Recém-nascido e as respostas aos estímulos dolorosos foram comparadas. RESULTADOS: Ambos os estímulos de sucção proporcionaram efeito analgésico, resultando em respostas a dor menores se comparados ao controle (p0.05). CONCLUSÃO: Tanto o estímulo de sucção nutritiva quanto a sucção não nutritiva provaram ser métodos eficazes no alívio da dor em recém-nascidos.

Objective To compare the occurrence of tooth erosion (TE) and dental caries (DC) in adolescents with and without risk behavior for eating disorders (EDs). Method A controlled cross-sectional study involving 1,203 randomly selected female students aged 15–18 years was conducted in Brazil. Risk behavior for EDs was evaluated through the Bulimic Investigatory Test of Edinburgh and dental examinations were performed. Results The prevalence of risk behavior for EDs was 6%. Twenty adolescents (1.7%) were identified with severe risk behavior for EDs and matched to 80 adolescents without such risk. Among the severe risk group, 45% of adolescents were affected by TE and 80% by DC compared with 8.8 and 51.3%, respectively, in the matched group. Adolescents with severe risk had higher chances for TE (OR = 10.04; 95% CI = 2.5–39.4). Discussion In this study, a severe risk behavior for EDs was significantly associated with TE, but not with DC. © 2013 Wiley Periodicals, Inc. (Int J Eat Disord 2013; 46:677–683)

The aim of this cross-sectional study was to assess awareness and attitudes related to tooth erosion among dental students, patients, and faculty members in a Brazilian dental school. Data were collected by means of a self-applied questionnaire that was distributed among 298 participants. The response rate was 89.6 percent. Chi-square and Fisher's exact tests were used for statistical analysis (p