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We report the case of a 75-year-old female patient with a big tumour in the lower rectum with intestinal obstruction and lower gastrointestinal bleeding history who underwent a tumour biopsy under laparotomy and end colostomy at another hospital in Peru. She came to our institution for clinical evaluation with a pathology result of a rectal gastrointestinal stromal tumour. An extra elevator abdominoperineal resection was performed with tumour-free margins. The histology confirmed a high-grade (G2) rectal gastrointestinal stromal tumour with a mitotic index of 27/50. DOC-1 (+) and CD117 (+) in immunohistochemistry. Genomic DNA was extracted from the paraffin-fixed tumour sample, and c.1504_1509dupGCCTAT (p.Ala502_Tyr503dup) mutation was detected in exon 9 of the KIT gene. Imatinib 400 mg per day for 3 years was indicated as adjuvant treatment. Currently, she has a disease-free survival of 12 months.

Objetivo: Identificar las características epidemiológicas y clínicas de las cardiopatías congénitas en niños menores de 5 años en el Hospital "Almanzor Aguinaga Asenjo" durante enero - diciembre de 2012. Material y Métodos: Estudio cuantitativo de diseño descriptivo transversal, población escogida niños menores de 5 años atendidos en Hospital Nacional "Almanzor Aguinaga Asenjo", diagnosticados con cardiopatías congénitas entre enero - diciembre de 2012, los datos se obtuvieron del Sistema de Gestión Hospitalaria mediante el código CIE-10 (Q00-Q99) en la Oficina de Inteligencia Sanitaria del Hospital Nacional "Almanzor Aguinaga Asenjo" obteniéndose una lista con la cual se solicitó a la Oficina de Registros médicos las historias clínicas para la confección de la base de datos en Excel 2010. Resultados: Se tuvo 109 pacientes, predominando sexo masculino (55%) entre 6 meses y 2 años (40%) procediendo de Lambayeque (55%). Predominaron las cardiopatías congénitas acianóticas (92%), siendo comunicación interventricular (CIV), comunicación interauricular (CIA) y persistencia del conducto arterioso (PCA) los más frecuentes, mientras que las cianóticas (8%), el 56% representól a Tetralogía de Fallot. Su tratamiento: 38% farmacológico, 22% observación y 40% quirúrgico. Conclusión: Las cardiopatías congénitas más prevalentes en el Hospital Nacional Almanzor Aguinaga Asenjo son similares a las reportadas en literatura nacional e internacional. Con mayor frecuencia en sexo masculino, procedentes de Lambayeque y según tipo, acianóticas, siendo comunicación interventricular en mayor proporción, y su tratamiento prevalece el conservador, siendo observación y farmacológico predominantemente. Objective: Identify the epidemiological and clinical characteristics of congenital cardiopathies in children under 5 in "Almanzor Aguinaga Asenjo's" Hospital during January - December 2012. Material and Methods: Quantitative descriptive cross sectional study design, the chosen were children under 5 years who were diagnosed with congenital cardiopathies in "Almanzor Aguinaga Asenjo's" Hospital between January to December 2012, data were obtained from the Hospital Management System using the ICD-10 (Q00 -Q99) in the area of Health Intelligence of "Almanzor Aguinaga Asenjo's" Hospital and obtained a list of which doctors office requested medical records for making database in Excel 2010. Results: 109 patients, predominantly male (55%) between 6 months and 2 years (40 %) from Lambayeque (55%), predominated acyanotic congenital cardiopathies (92%), ventricular septal defect (VSD ) , atrial septal defect (ASD ) and patent ductus arteriosus (PCA ) the most common, whereas cyanotic congenital heart disease (8 % ) , 56% represented by Tetralogy of Fallot. Treatment, 38% with drug treatment, 22% observation and 40% surgical treatment. Conclusion: The most prevalent congenital heart disease in the Almanzor Aguinaga Asenjo's Hospital are similar to those reported in national and international literature. More frequently in males, from Lambayeque and of the acyanotic type, being the interventricular communication most frequently, and treatment prevails conservative, observation and pharmacological depending on hemodynamic stability.