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2. Exercise for depression and depressive symptoms in older adults: an umbrella review of systematic reviews and Meta-analyses

Author

Roberto L. Bigarella, Dener lizot Rech, Luciano Selistre, Lucas Goldmann Bigarella, Lucas Ferrazza Mazurkiewicz, Vinícius Remus Ballotin, and Ana Carolina Ballardin

Subjects
medicine.medical_specialty, Cochrane Library, law.invention, Meta-Analysis as Topic, Randomized controlled trial, Older patients, law, Humans, Medicine, Depressive symptoms, Depression (differential diagnoses), Aged, Randomized Controlled Trials as Topic, Exercise intervention, Depression, business.industry, Exercise Therapy, Psychiatry and Mental health, Systematic review, Strictly standardized mean difference, Physical therapy, Geriatrics and Gerontology, Pshychiatric Mental Health, business, Gerontology, Systematic Reviews as Topic
Abstract

Objectives We aimed to gather and update the evidence on the impact of exercise on late-life depression. Method We conducted an umbrella review of meta-analyses of randomized controlled trials (RCTs) that assessed the effects of an exercise intervention for depression in older adults (e.g. 60+). Searches were conducted in Scopus, Web of Science, Embase, PubMed, BIREME, LILACS, SciELO, Cochrane Library for Systematic Reviews, and Opengray.eu. Methodological quality was assessed using A MeaSurement Tool to Assess Systematic Reviews (AMSTAR 2). Data analysis was performed with RStudio (version 4.0.2) and the generic inverse-variance method was used to pool the effect sizes from the included studies. Results Twelve meta-analyses of 97 RCTs were included. The AMSTAR 2 rating was considered critically low in five studies, low in six studies, and high in one study. The effect size expressed by the standardized mean difference (SMD) varied between studies from -0.90 (95% CI = -1.51; -0.28) to -0.14 (95% CI = -0.36; 0.07) in favor of the exercise intervention. Pooling of the effect sizes produced a statistically significant moderate effect in which exercise was associated with lower levels of depression and depressive symptoms (OR = 2.24, 95% CI 1.77; 2.84). Conclusion Our findings suggest that exercise produces a moderate improvement in depression and depressive symptoms in older patients. We recommend providing physical activity for older adults. Key-points We investigated the effects of exercise interventions for depression in older adults. Supplemental data for this article can be accessed online at https://doi.org/10.1080/13607863.2021.1951660.

Published
2021
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4. The Impact of Obesity on Plastic Surgery Outcomes: A Systematic Review and Meta-analysis

Author

Lucas Goldmann Bigarella, Ana Carolina Ballardin, Luísa Serafini Couto, Ana Carolina Porciuncula de Ávila, Vinícius Remus Ballotin, Anderson Ricardo Ingracio, and Matheus Piccoli Martini

Subjects
Reoperation, Humans, Surgery, General Medicine, Obesity, Overweight, Plastic Surgery Procedures, Surgery, Plastic
Abstract

Background Obesity is a potential risk factor for complications in plastic surgeries. However, the data presented by primary studies are contradictory. Objectives The aim of this study was to summarize and clarify the divergences in the literature to provide a better understanding of the impact of obesity in different plastic surgery procedures. Methods We conducted a systematic review and meta-analysis of the impact of obesity on plastic surgery outcomes. Searches were conducted in MEDLINE, LILACS, SciELO, Scopus, Embase, Web of Science, Opengrey.eu, and the Cochrane Database of Systematic Reviews. The primary outcomes assessed were surgical complications, medical complications, and reoperation rates. The secondary outcome assessed was patient satisfaction. Subgroup analysis was performed to investigate the impact of each BMI category on the outcomes. Results Ninety-three articles were included in the qualitative synthesis, and 91 were used in the meta-analysis. Obese participants were 1.62 times more likely to present any of the primary outcomes (95% CI, 1.48-1.77; P < 0.00001). The highest increase in risk among plastic surgery types was observed in cosmetic procedures (risk ratio [RR], 1.80; 95% CI, 1.43-2.32; P < 0.00001). Compared with normal-weight participants, overweight participants presented a significantly increased RR for complications (RR, 1.16; 95% CI, 1.07-1.27; P = 0.0004). Most authors found no relation between BMI and overall patient satisfaction. Conclusions Obesity leads to more complications and greater incidence of reoperation compared with nonobese patients undergoing plastic surgeries. However, this effect is not evident in reconstructive surgeries in areas of the body other than the breast.

Published
2022

5. Endocrinologia e Imunologia

Author

Henrique Mota Dias Gabriel da Silva, Paula Gouvêa Abrantes, Fábio Giancoli Jabour, GABRIELA DE PAULA FAGUNDES NETTO, Álvaro Maciel Campos Resende, Rafael Matoso de Oliveira Figueiredo, HUGO DUARTE MASCARENHAS DE CASTRO, Gabriela Carneiro Neves, André Mourão Costa Lima, Danielle Souza Silva, Dhener Gonzaga Abade, Gabriel Cavalcanti de Mello Moura, João Vitor Prado Rodrigues, José Reinaldo Corrêa Roveda, Olívio Marques Brum, Rayan Viana das Chagas, JAQUELINE VASCONCELOS DA SILVA GUSMÃO, Paula schatz de Gusmão Lyra Cavalcanti, CAMILA YANDARA SOUSA VIEIRA DE MELO, Vitor Augusto Pereira de Carvalho, Bruna Cappelli Coutinho, Bruno de Oliveira Vaz Lanza, Abraão Mendes Peixoto, Bruno Lucas de Andrade, Pedro Duarte Moreira Andrade, Vinícius Nunes Soares, Vitória Moraes de Campos Belo, Rodrigo Tavares de Lanna Rocha, João Victor Cota Postali, Larissa Verçosa Tramontina, Pedro Antônio Oliveira Aquino Gusmão, Victor Buchini de Freitas, Beatriz Saez Bragança Rezende, Gabriela Freitas Moreira, Mariana Santos de Andrès Abreu, João Henrique Vilaça Santiago, Gabriela Vaz Campos, Letícia Fogaça Saud, Livia Viana Trevisan, Daniela Vieira e Silva Vitor, Stefani Z Monção, Camilla Caramaschi Vernizzi, Gretha Faber Bortolan, Bárbara Mamede Silva Machado, Marcelo Eduardo Ramos Barbosa, Gabriela da Silva Cervi Machado, Maria Luiza Ricarte Ruggeri, RAFAELA SILVEIRA XIMENES DE SOUZA, Ana Raquel Whitaker Filipe, Carla Rossini Crepaldi, Mila Pontes Ramos Cunha, Eugênia M de Q F B da Silveira, Iris Lopes Veras, Ana Beatriz de Alexandria Leal Vasconcelos, Márcia Gomes Marinheiro Coelho, Fernanda Pimentel de Oliveira, Mateus Sampaio Coelho, Isabela de Araújo Belo Passos, Gabriely de Oliveira, Angel Adriany da Silva, Silvia Regina Seibel de Matos, Gustavo Henrique Sumnienski Bertoldi, Isabela Yurie Yamada, Gabriela Somma Gomes, Sofia Landim Teixeirense Pinheiro, Letícia Elen Carpenedo Frare, Milena Gonçalves Guerreiro, Joanna Lara Castelo Rodrigues, Mary Morioka, Bruna Duz, Julio Soares Curi, Caroline Brand, Cézane Priscila Reuter, Marcos Fonseca Melo, Ana Clara Rosa, Gabriel Araújo Moura Leite, Géssyca Tolomeu de Oliveira, Gustavo Sabec Folgueral, Hygor Cordeiro Fontes, Laila Fernandes da Cunha, Luciana Siuves Ferreira Couto, Victor Miguel Fernandes de Moraes, Vítor Luiz Rocha Rodrigues, Vitória Dias Dos Santos, Leticia Ferreira Santos Brito, Lucas Reis Oliveira, Bianca Santos Melo, Katlhen Cruz Santana, Bruna Passos Santos, Yane Passos de Oliveira, Mariana Moraes Vieira, Maria Beatriz Meneses Melo, João Victor Oliveira Prado, Tássia Virgínia de Carvalho Oliveira, SAMUEL MELO RIBEIRO, Mauro Marques Lopes, Jhennifer Stephanye Venturato Vieira, Gustavo Coutinho Nogueira Pereira, BIANCA RODRIGUES TAVARES, Juliana Vieira Gama, MARCOS ANTÔNIO RIBEIRO MENDES, Ana Carolina de Sousa Andrade, Caroline Souza Araújo, Laís Correa Marques, Maria Nila Sutana de Mendonça, Thainã Medeiros de Souza Andrade, Renata Giacomini Occhiuto Ferreira Leite, Elomar Rezende Moura, Victoria de Andrade Santos, Leticia Rocha Sobral, ryan fernando menezes, Kamille Costa Nunes, Alessandra Vitoria de Menezes Nunes, Julia Alves Santos, Lorena dos Santos Blinofi Cruz, Izabelle de Lourdes Pereira Ribeiro, Halley Ferraro Oliveira, Clara Lopes Lima, Laura de Araujo SOARES, Beatriz Maria Monteiro Souza, Vinícius Fonseca Bernardes, Gustavo Junho Toledo, Helena de Cunha Lopes Lima, Laura Teodoro Campos Faleiros, Mateus Gomes Polo, Rafaela Silveira Ximenes de Souza, Rosinês Padilha da Silva, Liliana Portal Weber, Luísa Santiago Ramos, Ana Clara Resende Rodrigues, Eduarda Viana de Souza, Gabriel Oliveira Souza, Igor Tomoyuki Kamino, Paulo Augusto Carvalho Miranda, Andressa Mendes de Sousa, Myrna Beatriz de Melo Oliveira, Larissa Mota Oliveira, Marcely Juliana Silva de Meneses, Bárbara Cândida Nogueira Piauilino, Carlos Daniel de Sousa Lima, Maria Clara Leal Cortez, Maria Luana de Moura Sousa, Lucas Ferrari da Silva Mendes, Amanda Vitória da Rocha Granja, Maysa Mauriz de Galiza Robatini Ramos, Ramona Dias Horta, Alice Maia Marinho de Andrade, Christian Diego Hernández Camacho, Kittaro Oittavo Moreira Teixeira da Luz, Lucas Henrique de Carvalho Machado, MARIANA NUNES LIMA DIAS, Gabriela Dantas Carvalho, Rayssa Maria de Araújo Carvalho, Klégea Maria Cândido Ramos Carvalho, Rebeca Múálem de Moraes Santos, Guilherme Barroso, Ana Carvalho Kilson, André Mendonça Palhares, Bruno Guerra Paiva, Carlos Augusto Wolmer de Carvalho Rocha, Chiara Giovanna de Paiva Ayres, Cibele Morais da Vitória, Felipe Barros, Gabriel Chaves Rettore Leandro, Gabriela Cordeiro Costa, Giovanna Galantini Silveira, Isabela Galantini Silveira, Isabela Soares Bôa Morte, Isabella Zechlinski Machado, Laura Tomaz Silva, Luiz Francisco Campos Freitas, Luiz Sequeira Fernandes, Luiza de Souza Cabral, Maria Júlia Giraud Mansilha, Mariana Madureira Frois, Mariana Ribeiro Nobre, Nicholas Franco SantAna Medeiros, Rafaela Pessoa Alves Luso, Renata Viana Hoffmann Monteiro Guedes, Stella Assis Guerra, Thaila Bastos Silva da Cruz, Paula Melo Vale, Thaís Toledo Nora, Rachel Calazans de Oliveira Costa, Victor Silame Braga, Vitoria Grecco Collodetti, Júlia Bueno Nascimento Jannotti, Natália Campos Ramos, Juliana Gonzaga Araújo Clark, Ulisses Guimarães Fernandes, Leandro Petronetto Loureiro, Pedro Terra De Martin Galito, Felipe Terra De Martin Galito, Higor Fontana Nicoli, Vinicios Teixeira de Carvalho Soares, Eduarda Maria Cetto Meira, Pedro Flavio Antunes Gallo Pinheiro, Carla Gomes da Silva Lacerda, Ramon Machado Avelar, Nádya Ribeiro Corrêa, João Paulo Pereira Martins, Juliana Aguiar Cavalcante Diniz, Juliana de Assis Pires, Karenn Tavares Kiepper, Maria Carolina Gonçalves Lana, Natália Andrade Lanna, Tatiana Borges Quadros, Matheus Neres Batista, Weberton Dorásio Sobrinho, Joel A S, Eliana A N Veloso, Karolinne Dorneles Dias, Amanda Carolina de Melo Gonçalves, Laura Vilela Buiatte Silva, Carla Azevedo Zaibak, Bianca Vieira de Sousa, Nathálya Faria Alves, Lanna do Carmo Carvalho, Luciano Souza Magalhães, Luana Vilela Matos, Layanne Cintra Soares, Paula Castro Ferreira, Isys de Paula, Letícia Priscila dos Anjos Goulart, Laura Vitória Melo Gomes, Beatriz Cozzer, Ana Clara Gambarini Mello, Lara Gouvêa de Azevedo, Beatriz Teixeira Lodi, Kelly Cristina Mota Braga Chiepe, Gustavo Henrique Silva Sidrim, Marina Oliveira Quinto, Ianca Siqueira Libânio, Paula Luiza Isabella Cruz, Mariana de Fátima Rodrigues da Silva, Letícia de Castro Nascimento, Bárbara Viana Marchesi, Gabriella Rocha Vilela, Renzo Câmara Arreguy, Isabella Almeida Sá, Cíntia Dias Vieira Bemfica, Milena Aguiar de Oliveira, Stefani Zaqué Monção, Débora Silva Ciríaco, Bruna Piassi Guaitolini Vargas, Marina Alvarenga Andrade Siqueira, Júllia Beatriz Araujo Souza, Ana Luiza Almeida Menezes, Beatriz Oliveira Santos, Edson Santana Gois, Eduarda Lavínia Carneiro Santos, João Victor Santos Melo, Leila Maria Lemos Nascimento, Mariana Sattler Lima Medina, Rosa Carolina Santos De Oliveira, Vitória Dias dos Santos, Igor Silva Matias, Aalec Rinhel, Andrei Biliato Colmanetti, Amanda Pita Oliveira, Filipe Abrão Borges Salomão, Guilherme Assis Xavier, Lívia dos Santos Souza, Marcela Mamede Elias, Mateus Nascimento Barbosa Barros, Murilo Pita Oliveira, Paula Cristina Santos Soares, Thales Milhorim da Silva, Ana Theresa Simões Rosa Borges, Maria Luiza Costa Santos, Sophia Mourão Gontijo de Castro, Mariane da Mata Morato Mendes, Eduarda Paula Markus Xavier, Ranieri Alvin Stroher, André Luiz Cezar, Ana Elisa Choucair Hosken Arão, Anna Carlinda Arantes de Almeida Braga, Igor Yury Silva, Gabriela de Alcântara Fonseca, Ariel Eugênio Salgueiro de Almeida, Vitor Medeiros Delgado, Patrícia Oliveira Lima de Macedo, Louyse Jerônimo de Morais, Júlio César Benjamim Moreira Silva, Vitor Rodrigues de Miranda, Bárbara Coelho Pereira, Amanda Barros França, Danielle Ribeiro Duarte, Ana Paula Tobias Antunes, Sophia Avelar Freitas, Priscilla Martins Valadares, Helena Rodrigues de Miranda, Luísa De Luca Felicíssimo, Rafaella Moreira Gonçalves Magalhães, Maria Laura Pires de Carvalho Pereira, Luiza Aguiar Puff, Larissa Chaves Teodoro, Fernanda Gualberto Costa Campos, Tiago Pessoa Mendes, Flávia Chaves Cardoso de Paula, Arthur Andrade Brum, João Pedro Campos Pereira, Fernanda Valcarenghi, Guilherme Amaral Stangherlini, Ana Carolina Porciuncula de Ávila, Murillo Cesar Gionedis, Elise Cristina Reolon de Mello, Ana Carolina Ballardin, Gabriel Michelin De Carli, Rafaela Dresch Pereira, Amanda Marques Coelho, Davidson de Lima Cavassola, Giovanna de Carvalho Meneses Costa, Maria Júlia Ribeiro da Costa, Vinícius Leite Siebra, Bruno Araújo Rocha, Carlos Wesley Ribeiro Pereira, Felipe Gomes da Silva, Francisco Socorro Rocha, Gabriel Melo de Sousa, Jadsonn Souza de Melo, Lorena Terra Campos, Alice Maciel de Lacerda, Artur Moreira Rodrigues, Bárbara Ribeiro Diniz, Bruna Pereira Vilaça, Matheus Álvaro Colbert Câmara, Pedro Alcântara Antunes Lopes, Bárbara Campolina Carvalho e Silva, Bárbara Belloni Perez Couto, Izabella Pereira Chaves, Lucas Pinheiro Costa, Letícia Freitas de Castro Silva, Elisa Pinheiro Weber, Debbie Priscila Weber, Ana Clara Moreira Noronha Fonseca, Bárbara Luiza Klein, Jamile Cássia Gonçalves Aniceto Ferreira, Maria Eduarda Tavares de Oliveira, Maria Fernanda Luz Silva, Kawanny Kennedy de Arruda Batista, Milena Maria da Silva Aguiar, Fabiano dos Santos, Geovani Andriel Alves Martiniano da Silva, Letícia Kelly Melo Santana, Lívia Leandro de Souza Pereira, Maria Eduarda Osório Marafante, Weslley Jonathan Lopes da Penha, PAULA FONTES LELIS, Juliana Souza Martins, Júlia Gatti Ladeia Costa, Ana Laura Martins Marra Magno Lucindo, Gabriella Soares de Souza, Tiago Araújo Monteiro, Estevão Curado Domingues, Leilianny Alencar Secundino Curado, Amanda Holanda de Mesquita, Aline Castro de Almeida, Isabela Araujo Schmidt, Laura Krepk Vieira, Breno Veggi Godinho, Olívia Féres Varela, Lara Bastos Spinelli Pinto, Cecília Barra de Oliveira Hespanhol, Letícia F Soares, Matheus Itaborai de Castro Nogueres, Thais Sette Espósito, Amanda do Carmo Gusmão, Andressa de Araujo Rodrigues, Daniela O W Rodrigues, Patricia Pimenta Nunes, Hellen Louize Pacheco di Firmo, Laiane Cristina De Camargos Silva, Luiza Lacerda Lima, Lara Campos Martins, Luiza Fernandes Rios, Beatriz Campos Garcia, Giovana Campos Garcia, Cecilia Miranda Gonçalves, Gabriella Bretas Alves, Nayla Fernanda de Oliveira Tanus, Gustavo de Moura Campos, Vitória Guerra Melo, Alice Costa Duarte, Isadora Pessoa Coimbra Rabello, Ana Julia Amaral Melo, Maria Carla Silva Teixeira, lara Resende Melgaço, Marielle Caroline Barcelos, Caroline Marinho Simião, Giulia Cazzoletti, Marina Silveira Braga, Luísa Guerra Brandão, Rafael Bessa Fleming, Sophia Filgueiras Vieira, ANA CAROLINA AMORIM OLIVEIRA, Eduarda Santana dos Santos, George Lucas Santos Pereira, Juliana Thalia Souza de Moura, Lara Santana Bastos, Larissa Gusmão Guimarães, Julianne Alves Machado, Maria Ingrid Ferreira Dias Gregório, Luana Pereira da Silva, Ráira Thiele Ribeiro FEITOSA, Sarah Buarque Gomes de Moura, Lívia Maria Alves de Souza, Fabiana Oliveira dos Santos Gomes, Caio Fossalussa da Silva, Anny Isabelly dos Santos Souza, Fabio Franceschini Mitri, João César Guimarães Henriques, Raquel Carmo Araújo, Gabriela de Oliveira Carvalho, Matheus Jannuzzi Moreira de Mendonça, Vitória Aparecida Cunha, and Pamela Andrea Alves Durães

Published
2021
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