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Introduction Smoking has been linked to cancer occurrence and survival rates for a long time. However, there is little research into the impacts of smoking on oncological treatments. The aim of the study is to show the impact that smoking can have on the effects of cancer therapy. Methods Epidemiological situation analysis of the malignant diseases based on the data of incidence and mortality and the impact of smoking on the results of treatment. Results At the time of establishing the diagnosis, the incidence of smoking varies from 10 to 95 per cent ( 60% for lung cancer). The previous research indicates that continuing smoking after the establishment of a diagnosis can impact the treatment outcomes and is related to worse prognosis and survival rate. Active smoking can be connected to lower survival rates with advanced non-small cell lung cancer, limited small cell lung cancer, bladder cancer, and upper tract urothelial cancer. The smokers suffering from prostate cancer have a higher risk of death outcomes and worse prognoses after the treatment. The research has shown that there is a link between smoking and slower wound healing in operated patients and that it can also intensify the side-effects of chemotherapy and prolong the responses to radiation. Conclusions It is essential to increase knowledge about the health benefits of quitting smoking in order to advance the results of oncological treatments. Implemented smoking cessation programs need to be adapted to oncology patients.

To assess the motivation and barrier factors influencing participation of women in opportunistic breast cancer screening in Belgrade, Serbia, and to detect changes in these factors over time.A cross-sectional study has been carried out at the Institute for Oncology and Radiology of Serbia in 2009 and 2016 among women aged 40 to 69 years from Belgrade who came at the Institute for opportunistic breast cancer screening. The demographic characteristics, data regarding breast exams practices, screening motivators and barriers and sources of information on breast cancer were collected by self-administered questionnaire.The questionnaire was completed by 478 women in 2009 and 453 in 2016, with increase in women reporting regular mammograms or at least one previous mammogram (from 30.1% to 58.6%, p=0.000). In 2009, the most frequent motivating factors were health maintenance (36%), friend's advice, TV, cancer in the family or fear of breast cancer; in 2016, advice from gynecologist (significant increase from 10.9% to 37.7%, p=0.000), health maintenance, family cancer and fear of cancer. The most frequent reasons for not going to exams regularly were absence of breast problems, crowded doctor's offices and no family breast cancer.These findings provide information on motivation and barrier factors that may influence women's decision to participate in opportunistic breast cancer screening. Those factors have changed over time and the role of physicians has increased significantly. Further exploration of motivating and barrier factors and the extent of their association with actual women's behavior would be helpful for the development of interventions to improve organized and opportunistic screening participation.

Introduction It has been proven that tobacco is the most dangerous single risk factor for development of many chronic diseases, cancer or early death. Tobacco smoke has more than 7000 chemicals, at least 250 are known to be harmful and more than 50 are known to cause cancer. Although quit smoking medications – substitution therapy has been approved and officially acknowledged as well as programs for stop smoking, the smoking rate is still very high. More than 1/6 of world population (1.1 billion) are smokers. The aim of this work is to present the importance of carrying out stop smoking programs for patients dealing with cancer. Methods The analysis of epidemiological situation of malignant disease is based on information of incidence and mortality as well as on smoking impacts. Results Researches show that larger part of oncological patients recognizes smoking as harmless and determination of diagnosis motivates these patients to stop smoking. Estimations show that 38% to 65% of cancer patients stop smoking in the first year after confirming diagnosis. Quitting smoking during oncological treatment is related to: better treatment response, reduced risk of complications, better quality of life and reduced risk of disease progression. Quitting smoking among oncological patients will affect long-term health as well by reducing risks of development of other diseases (heart attack, stroke). Conclusions All patients disregarding the stage of disease during oncological treatment may benefit from smoking cessation and have a right to quitting smoking treatment. Health care workers may improve motivation and influence quitting by providing help, giving advice and prescribing medications.

Background/Aim. Bearing in mind a high smoking prevalence in Serbia (34% in adult population; men 38%, women 30%) and leading role of health professionals in intervention and prevention, a cross-sectional study was performed smong the representative sample of health professionals in Serbia. The aim of the study was to identify predictors of smoking and smoking cessation prior to the total smoking ban in November 2010. Methods. In this nationwide study, 3,084 physicians and nurses from 4 types of institutions and four geographical regions were selected and 2,282 included (response rate 74.0%). Data were collected using a self-administered structured questionnaire. Standard statistical methods were used to calculate prevalence rates, and multivariate logistic regressions to evaluate independent predictors of smoking pattern. Risks were expressed as odds ratios (OR) which represent approximation of relative risks of exposed persons with 95% confidence intervals (95% CI). Results. We found a high smoking prevalence of 38.0%, the same for women and men (37.8% and 37.6%, respectively; p = 0.138), higher among nurses (41.7%) than physicians (29.1%) (p = 0.000), as well as among those employed in general hospitals (42.6%) and institutes of public health (43.8%) (p = 0.000). Significantly increased risk of being an ever or current smoker was noticed for nurses (OR = 1.75, 95% CI 1.42-2.14; and OR = 1.91, 95% CI 1.52-2.40, respectively), those employed in general hospitals (OR = 1.37, 95% CI 1.09-1.73 and OR = 1.40, 95% CI 1.09-1.79, respectively), and with worse self-estimated health (OR = 1.15, 95% CI 1.02-1.30; and OR = 1.17, 95% CI 1.02-1.34, respectively). Intentions to quit smoking or to reduce the number of cigarettes were more frequent in women (OR = 1.51, 95% CI 1.01-2.27) and participants who worse evaluated their health (OR = 1.74, 95% CI 1.39- 2.18). Conclusion. High smoking prevalence in health professionals could be a barrier for the full implementation of smoking ban in health institutions in Serbia. Smoking cessation programs at workplaces, formal education in smoking cessation techniques, and better Law enforcement by health administrations should be implemented.

The aim of this study was to develop a new material which has high hydrogen storage capacity and hydrogen absorption/desorption rate. This material, which is based on cobalt powder onto which palladium was chemically deposited can be used in environmentally friendly energy generation processes, thus ensuring preventive protection of human health. Hydrogen absorption was investigated using differential scanning calorimetry (DSC) and by measuring hydrogen pressure under isothermal and non-isothermal conditions in a chamber containing either pure cobalt powder either cobalt powder onto which palladium was chemically deposited (Co-0.003 Pd). The mechanism of hydrogen absorption has been described. It was noticed that palladium catalyses hydrogen absorption by dissociating the adsorbed H2 molecules into H atoms more rapidly on its own atoms than on cobalt ones. The catalysis of dissociation of H2 molecules enabled hydrogen absorption into Co-0.003 Pd powder to occur at lower temperatures. The results of this study enable integration of technological and public health investigation in order to ensure preventive protection of human health through enviromental protection.

Background and context: The Institute of Oncology and Radiology of Serbia (IORS), supported by the Ministry of Health, launched the project Knowledge Against Cancer in 2015, whose aim was to prepare educational material for cancer patients. Thirteen brochures were presented on WCC in Paris in 2016. The IORS conducted a survey among oncology patients in January 2017 for them to evaluate the distributed brochures and suggest the topics for new educational material. Aim: This paper aims at evaluation of brochures for cancer patients which were created during the project and its primary goal is to define new topics for future educational material. Strategy/Tactics: The study includes 348 respondents (92% women, 8% men) with average age of 54.77 ± 13.26 and predominantly highly educated (45.4%). 90% of the respondents has evaluated this kind of educational material as significant. The study has also examined the choice and relevance of topics and the quantity and usage potential of new data. The analysis has shown that most patients are interested in including psychological aspects of cancer treatment as a new topic (76%) and in including topics concerning healthy lifestyles (69%). As the majority of the respondents are women, the significant interest has been shown for topics concerning lifedem and tumor radiation of female genital organs (over 85% of female respondents). Based on the results obtained through survey and consultations and interviews with patient support group and patients associations the educational brochures were created. Program/Policy process: In 2017, nine new topics were prepared by multidisciplinary teams from IORS: Brochure: psychological support for oncology patients, the manual for family and friends, the manuals for patients on radiation of tumors on female genital organs, for head and neck tumors, lymphoedema - prevention and treatment, treatment of thyroid gland cancer with radioactive iodine, tumor markers and laboratory diagnostic, prevention of malign illnesses and quitting smoking. Outcomes: Brochures are currently available both in paper and on the Web site free of charge. The design of mobile phone application is planned for the future. The educational material is not only presented and distributed to cancer families and the public but also to health professionals and medical workers. What was learned: The research has shown that this educational material is very important for cancer patients and that with adequate information and data such patients can improve life quality predominantly through the reduction of fears and anxiety, development of coping mechanisms to deal with the cancer diagnosis and treatment and encouraging them to take active part in cancer treatment.

Efficient prevention is strongly correlated with an early detection of breast cancer. The common effort of many researchers in this field resulted in the selection of the most prominent risk factors related to breast cancer. In this paper we present a neural network based model for the efficient automated identification of women at high risk of developing breast cancer from a wide, healthy population on the basis of data, referring to a properly selected set of risk factors and symptoms. Using this model we achieved a highly accurate classification and also the initial set of features reduction.

Cervical cancer is the second most common female malignancy in Serbia, after breast cancer, with 1089 new registered cases and an age-standardized incidence rate of 27.2 per 100,000 women in 2002. It is the fourth leading cause of cancer death with 452 deaths and an age-standardized death rate of 7.2 per 100,000 women. Compared with other European countries, the incidence of cervical cancer in Central Serbia is the highest. Regional differences in incidence are pronounced in Serbia with the lowest age-standardized incidence rate (16.6 per 100,000 women) registered in the Ma~- vanski region and the highest in eastern Serbia and the region of Belgrade where the rates are double at 32.5–38.1 per 100,000 women. Cervical cancer prevention in Serbia has relied on opportunistic screening that is characterized by high coverage in younger and low coverage in middle-aged and older women. Screening of selected groups of women employed in large companies is performed annually by many regional hospitals but this approach has little effect on morbidity and mortality. Recently, the Ministry of Health nominated an Expert Group to develop and implement a national cervical cancer screening program. A number of pilot projects have been undertaken with the results used for development of a national programme for cervical cancer screening. This is expected to be finalized in 2007, and launched over a 3-years period in order to cover all women aged 25–64 in entire Serbia.