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Research indicates inadequate evidence-based practice (EBP) implementation for autistic adolescents in schools, despite schools being the most accessed service system by autistic youth. It is critical for school personnel to have a systematic approach to select and adopt autism EBPs. The Autism Community Toolkit: Systems to Measure and Adopt Research-based Treatments (ACT SMART) is a packaged implementation process tool designed to facilitate autism EBP adoption and uptake in community agencies, with promising feasibility, utility, and effectiveness. The current study describes the first iterative study of a community-partnered, iterative redesign of ACT SMART for use in educational settings. Using mixed-methods (focus groups, surveys), we gathered district and school administrators', teachers', paraeducators', autistic students' and their caregivers' perspectives of the feasibility, usability, and appropriateness of ACT SMART. We also gathered recommendations for redesign to ensure its contextual appropriateness and usability in middle and high schools. Results indicated the perceived acceptability (satisfaction with ACT SMART), feasibility (practicability of ACT SMART), and appropriateness (perceived fit or relevance of ACT SMART) but more limited usability (extent to which ACT SMART can be used by educators to achieve intended goals) of ACT SMART for schools. Key modifications include integrating the toolkit with school structures (i.e., conducting training on professional development days, aligning budget planning with the district timeline, tying the toolkit to students' IEPs, aligning with school calendars) and content modifications (i.e., altering language, shortening assessments, incorporating toolkit engagement strategies) to improve usability in schools. The current study highlights the relevance and potential of tools targeting EBP selection and adoption support for public schools. Next steps include further application of community-partnered and human-centered design methods to further refine and finalize the redesigned ACT SMART Toolkit and subsequent feasibility pilot testing.

We aimed to characterize scenarios where magnetic resonance elastography (MRE) of the liver was ordered and its impact on clinical course and management. 96 consecutive MRE examinations and subsequent encounters over 14 months were reviewed. Indication for MRE of the liver and subsequent management were abstracted from the medical record. In all cases, non-invasive assessment of liver fibrosis was the primary indication and at least one additional rationale was noted. There was a significant decrease in recommendations to undergo liver biopsy after MRE. Additionally, a greater percentage of those recommended to undergo biopsy completed the procedure after discussion of the results. Given the significant cost and rare but serious risks of liver biopsy, MRE of the liver provides an attractive, safer alternative that may have a comparable impact on management, or select cases where biopsy is essential to guide management. We demonstrate the versatility of MRE in real-world hepatology practice, including its utility as a non-invasive surrogate for liver biopsy.

Microgravity exposure induces a cephalad fluid shift and an overall reduction in physical activity levels which can lead to cardiovascular deconditioning in the absence of countermeasures. Future spaceflight missions will expose crew to extended periods of microgravity among other stressors, the effects of which on cardiovascular health are not fully known. In this study, we determined cardiac responses to extended microgravity exposure using the rat hindlimb unloading (HU) model. We hypothesized that exposure to prolonged simulated microgravity and subsequent recovery would lead to increased oxidative damage and altered expression of genes involved in the oxidative response. To test this hypothesis, we examined hearts of male (three and nine months of age) and female (3 months of age) Long-Evans rats that underwent HU for various durations up to 90 days and reambulated up to 90 days post-HU. Results indicate sex-dependent changes in oxidative damage marker 8-hydroxydeoxyguanosine (8-OHdG) and antioxidant gene expression in left ventricular tissue. Three-month-old females displayed elevated 8-OHdG levels after 14 days of HU while age-matched males did not. In nine-month-old males, there were no differences in 8-OHdG levels between HU and normally loaded control males at any of the timepoints tested following HU. RNAseq analysis of left ventricular tissue from nine-month-old males after 14 days of HU revealed upregulation of pathways involved in pro-inflammatory signaling, immune cell activation and differential expression of genes associated with cardiovascular disease progression. Taken together, these findings provide a rationale for targeting antioxidant and immune pathways and that sex differences should be taken into account in the development of countermeasures to maintain cardiovascular health in space.

Background and aimsFatty liver disease (FLD), alcohol-associated and metabolically associated, often coexists. Increase in physical activity is associated with metabolic health and decreased FLD. We aimed to identify factors associated with physical activity and its improvement following FLD education in a racially diverse, vulnerable population.MethodsFrom February 19, 2020 to December 30, 2022, 314 adults with FLD at safety-net hepatology clinics in San Francisco were surveyed at baseline, immediately after FLD education, and at 6-month follow-up. After collecting clinical and sociodemographic data, logistic regression (adjusted for age, sex, and race/ethnicity) assessed factors associated with physical activity at baseline and its improvement following education.ResultsParticipant characteristics in those without vs with any physical activity were median age 49 vs 55 years, 64% vs 56% female, 66% vs 53% Hispanic race/ethnicity, 75% vs 55% obese, and 30% vs 22% consumed heavy alcohol, respectively. On multivariable analysis, older age was the only significant factor associated with physical activity at baseline (relative risk ratio 1.37 per decade increase, 95% confidence interval [CI] 1.07-1.75). Hispanic (vs non-Hispanic) participants had a significantly higher odds of improvement in physical activity (vs no change) 6 months after education (odds ratio 2.36, 95% CI 1.27-4.39). Among those with suboptimal or no physical activity at baseline, participants who consumed heavy alcohol (vs no drinking) had a significantly higher likelihood of achieving optimal physical activity following education (relative risk ratio 1.98, 95% CI 1.05-3.74).ConclusionDespite social and structural barriers, FLD education increased uptake of physical activity in vulnerable populations, especially among Hispanic individuals and those consuming heavy alcohol. Implementation of patient-centered education is important for FLD management.

This study aimed to explore the influence of feeding regimens on carcase traits and meat quality of Gangba lambs. Thirty healthy Gangba ram lambs at nine months of age and an average body weight of 14.08 ± 0.79 kg were randomly distributed into three treatment groups (10 replicates per group). The groups are as follows: a grazing (G) group without any supplementation and housing; a semi-grazing (SG) group provided with 200–300 g of concentrates and free access to oat hay off-pasture; and a stall-feeding (SF) group with 400–500 g of concentrates and free access to oat hay. The experiment lasted 85 d, comprising a 10-d adaptation period and a 75-d experimental period. Results showed that significant differences in carcase weight existed among groups, respectively, with the SF group having the highest weights and the G group having the lowest weights (p

Abstract Background and aim Migraine is a common disabling conditions which, globally, affects 15.2% of the population. It is the second cause of health loss in terms of years lived with disability, the first among women. Despite being so common, it is poorly recognised and too often undertreated. Specialty centres and neurologists with specific expertise on headache disorders have the knowledge to provide specific care: however, those who do not regularly treat patients with migraine will benefit from a synopsis on the most relevant and updated information about this condition. This paper presents a comprehensive view on the hallmarks of migraine, from genetics and diagnostic markers, up to treatments and societal impact, and reports the elements that identify migraine specific features. Main results The most relevant hallmark of migraine is that it has common and individual features together. Besides the known clinical manifestations, migraine presentation is heterogeneous with regard to frequency of attacks, presence of aura, response to therapy, associated comorbidities or other symptoms, which likely reflect migraine heterogeneous genetic and molecular basis. The amount of therapies for acute and for prophylactic treatment is really wide, and one of the difficulties is with finding the best treatment for the single patient. In addition to this, patients carry out different daily life activities, and might show lifestyle habits which are not entirely adequate to manage migraine day by day. Education will be more and more important as a strategy of brain health promotion, because this will enable reducing the amount of subjects needing specialty care, thus leaving it to those who require it in reason of refractory condition or presence of comorbidities. Conclusions Recognizing the hallmarks of migraine and the features of single patients enables prescribing specific pharmacological and non-pharmacological treatments. Medical research on headaches today particularly suffers from the syndrome of single-disease approach, but it is important to have a cross-sectional and joint vision with other close specialties, in order to treat our patients with a comprehensive approach that a heterogeneous condition like migraine requires.

Purpose: The article considers a methodological approach to the formation and determination of potential locations of logistics infrastructure: warehouse storage facilities, wholesale distribution centers for storage, marketing and trade of agro-food products. Design/methodology/approach: A study of 204 objects - administrative districts and cities of Kazakhstan, where the production, storage, distribution and trade of agri-food products is carried out. The standardization of indicators, cluster, correlation-regression, factor analysis was carried out, the method of ranking and center of gravity. Findings: At the first stage of the study, potential locations of distribution centers of agricultural products were identified based on the proposed criteria. Based on factor analysis, new factors have been formed in order to determine the criteria for choosing the location of the logistics infrastructure. Cluster analysis made it possible to differentiate territories and determine the characteristics of the logistics infrastructure for their placement, depending on their specialization. At the second stage, the potential locations of logistics infrastructure and the geographical location of objects on the territory of administrative-territorial units were clarified. At the third stage, with the help of weighting coefficients and an integral indicator of the attractiveness of the location of logistics infrastructures, the service area of the logistics infrastructure of storage, sales and trade is determined in accordance with potential locations on the territory. The proposed approach, in contrast to the existing ones, takes into account the peculiarities of the functioning of the storage, marketing and trade infrastructure and links these facilities with transport and warehouse availability in the regions. Research limitations/implications: The study is aimed at complementing existing approaches and methods for determining the location of logistics infrastructure facilities with a more detailed account of the specialization of districts and the economic potential of regions. Practical implications: The conclusions allow us to use different criteria when determining the location of logistics infrastructures depending on their purpose. They also provide important information in the process of designing logistics infrastructure, conducting a differentiated investment policy during their construction and operation. Originality: In this article, a new point of view is given on the choice of criteria for the placement and determination of the number of logistics infrastructure, based on their functional purpose, specialization of districts and the potential of regions, which increase their efficiency.

Background: Fatty acid-binding protein 4 (FABP4) is an adipokine that plays significant roles in the development of insulin resistance and atherosclerosis. High levels of soluble tumor necrosis factor receptors (TNFRs) including TNFR1 and TNFR2 are associated with renal dysfunction and increased mortality in patients with diabetes mellitus (DM). However, the association between circulating levels of FABP4 and TNFRs remains unclear. Methods: We investigated the associations of FABP4 with TNFRs and metabolic markers in Japanese patients with type 1 DM (T1DM, n = 76, men/women: 31/45) and type 2 DM (T2DM, n = 575, men/women: 312/263). Results: FABP4 concentration was positively correlated with levels of TNFR1 and TNFR2 in both patients with T1DM and those with T2DM. Multivariable regression analyses showed that there were independent associations of FABP4 concentration with body mass index (BMI) and estimated glomerular filtration rate (eGFR) after adjustment for age and sex in both patients with T1DM and those with T2DM. FABP4 concentration was independently associated with circulating levels of TNFR1 and TNFR2 after adjustment for the confounders in patients with T2DM but not in those with T1DM. Similarly, levels of TNFR1 and TNFR2 were independently associated with FABP4 concentration after adjustment for age, sex, systolic blood pressure, duration of DM and levels of eGFR, high-density lipoprotein cholesterol, and C-reactive protein in patients with T2DM but not in those with T1DM. Conclusion: FABP4 concentration is independently associated with levels of TNFRs in patients with DM, but the association is more evident in patients with T2DM than in those with T1DM.

Scaling up the use of evidence-based practice (EBP) for autism across service sectors and regions has presented a considerable challenge indicating a clear need for continued development. The California Autism Professional Training and Information Network (CAPTAIN) integrates implementation drivers into specific procedures and methodology as an implementation strategy to support statewide scale up. The current study was designed to evaluate the impact of CAPTAIN on provider-level outcomes including attitude toward, and knowledge, fidelity and use of autism EBPs, and overall classroom quality. Overall, results indicated variability across measures, with some significant differences between CAPTAIN-trained and non-CAPTAIN-trained providers. CAPTAIN-trained providers reported more openness to EBP. Significantly more CAPTAIN-trained direct service providers reported collecting fidelity of implementation data (X[superscript 2](2, N = 1515) = 10.95, p = 0.004), collecting student data (X[superscript 2](2, N = 1509) = 14.19, p = 0.001), and reported using their primary EBP with "most or all students" (X[superscript 2](2, N = 1514) = 11.41, p = 0.003) than providers not trained by CAPTAIN. In summary, these preliminary findings show promise for the efficacy of the CAPTAIN model to increase dissemination and implementation of EBP at the classroom level.

The effect of coating thickness (CT) on the microstructures, hardness, and wear of cold sprayed Ti-6Al-4V (CS-Ti64) coatings was systematically investigated since the prolonged high pressure CS deposition could change their microstructures and porosity levels. In addition, the CT was relatively important for their durability, performance, and service life. Therefore, the CS-Ti64 coatings with different CT of 100-3000 µm were prepared on commercially available Ti64 (CA-Ti64) substrates via high pressure CS processes. The CS-Ti64 coatings had low porosity levels wherewith severely deformed Ti64 particles with a crescent-shape could be seen in their cross-sectional microstructures. The hardness of the CS-Ti64 coatings increased with increased CT probably due to their lowered bulk porosity levels associated with longer high pressure CS deposition. As a result, the increased CT from 100 to 3000 µm resulted in a 9.8% decrease in the wear of the CS-Ti64 coatings. The wear of the CS-Ti64 coating with 3000 µm was 16.8% lower than that of the CA-Ti64 as all the CS-Ti64 coatings had lower wear than the CA-Ti64. It could be concluded that the prolonged high pressure CS deposition for the thick CS-Ti64 coatings had an influence on their porosity, hardness, and wear.

Abstract Artificial intelligence (AI) is revolutionizing the field of biomedical research and treatment, leveraging machine learning (ML) and advanced algorithms to analyze extensive health and medical data more efficiently. In headache disorders, particularly migraine, AI has shown promising potential in various applications, such as understanding disease mechanisms and predicting patient responses to therapies. Implementing next-generation AI in headache research and treatment could transform the field by providing precision treatments and augmenting clinical practice, thereby improving patient and public health outcomes and reducing clinician workload. AI-powered tools, such as large language models, could facilitate automated clinical notes and faster identification of effective drug combinations in headache patients, reducing cognitive burdens and physician burnout. AI diagnostic models also could enhance diagnostic accuracy for non-headache specialists, making headache management more accessible in general medical practice. Furthermore, virtual health assistants, digital applications, and wearable devices are pivotal in migraine management, enabling symptom tracking, trigger identification, and preventive measures. AI tools also could offer stress management and pain relief solutions to headache patients through digital applications. However, considerations such as technology literacy, compatibility, privacy, and regulatory standards must be adequately addressed. Overall, AI-driven advancements in headache management hold significant potential for enhancing patient care, clinical practice and research, which should encourage the headache community to adopt AI innovations. Graphical Abstract

Leaf economics spectrum (LES) describes the fundamental trade-offs between leaf structural, chemical, and physiological investments. Generally, structurally robust thick leaves with high leaf dry mass per unit area (LMA) exhibit lower photosynthetic capacity per dry mass (Amass). Paradoxically, “soft and thin-leaved” mosses and spikemosses have very low Amass, but due to minute-size foliage elements, their LMA and its components, leaf thickness (LT) and density (LD), have not been systematically estimated. Here, we characterized LES and associated traits in cryptogams in unprecedented details, covering five evolutionarily different lineages. We found that mosses and spikemosses had the lowest LMA and LT values ever measured for terrestrial plants. Across a broad range of species from different lineages, Amass and LD were negatively correlated. In contrast, Amass was only related to LMA when LMA was greater than 14 g cm−2. In fact, low Amass reflected high LD and cell wall thickness in the studied cryptogams. We conclude that evolutionarily old plant lineages attained poorly differentiated, ultrathin mesophyll by increasing LD. Across plant lineages, LD, not LMA, is the trait that represents the trade-off between leaf robustness and physiology in the LES.

For young adults (YAs), a cancer diagnosis and subsequent treatments may result in physical changes that can negatively impact body image (BI) and health-related quality of life (HRQL). Physical activity (PA) is an evidence-based tool found to impact both BI and HRQL. However, most research has focused on the perspectives of older adults with breast or prostate cancer. No research has explored the experiences of PA, BI, and HRQL in YA males affected by cancer. A qualitative study was designed for YA males diagnosed with cancer between the ages of 20 and 39 years. Eligible participants were recruited through pre-existing exercise oncology studies, support organizations, and social media. Semi-structured interviews were conducted to understand participants’ experiences of PA, BI, and HRQL. All interviews were transcribed verbatim and analyzed using interpretive description. The participants were YA males (n = 7) with a mean age of 32.7 ± 4.0 years. Themes included a loss of identity due to cancer, building autonomy and identity using PA, and the “should” behind BI. PA for YA males living with and beyond cancer may support them in rebuilding their identity and BI. The development of exercise oncology resources for YA males may consider addressing BI through education or exercise prescription programs, with the goal of enhancing HRQL.

Abstract The work numerically investigated laminar natural convection heat transfer from the single sphere with a constant heat flux surface in air over the wide range of Grashof number ( $$10 \le Gr \le 10^{7}$$ 10 ≤ G r ≤ 10 7 ). The more efficient and precise numerical method based on Bejan et al. was employed here, the accuracy of which has been confirmed through validation against a single sphere case. The heat transfer characteristics were systemically analyzed in terms of isothermal contours and streamlines around the sphere, dimensionless temperature and velocity profiles. Additionally, local Nusselt number as well as local pressure and friction drag coefficients were studied with different Grashof number. In comparison to the sphere with uniform heat flux surface, the heat transfer from the isothermal sphere was found to be enhanced attributable to a more robust buoyancy force and a steeper temperature gradient. Moreover, the average Nusselt number for the sphere with a constant heat flux between 60.4 and 98.6% of the isothermal sphere’s value, this range being contingent upon the specific Grashof number. What’s more, the proposed correlation addresses a notable void in the predictive understanding of heat transfer from the sphere with uniform heat flux, which is scenario prevalent in various engineering applications, particularly for the cooling of electrical and nuclear systems, and offer values for academic research.

Abstract Background Surfactant is a well-established therapy for preterm neonates affected by respiratory distress syndrome (RDS). The goals of different methods of surfactant administration are to reduce the duration of mechanical ventilation and the severity of bronchopulmonary dysplasia (BPD); however, the optimal administration method remains unknown. This study compares the effectiveness of the INtubate-RECruit-SURfactant-Extubate (IN-REC-SUR-E) technique with the less-invasive surfactant administration (LISA) technique, in increasing BPD-free survival of preterm infants. This is an international unblinded multicenter randomized controlled study in which preterm infants will be randomized into two groups to receive IN-REC-SUR-E or LISA surfactant administration. Methods In this study, 382 infants born at 24+0–27+6 weeks’ gestation, not intubated in the delivery room and failing nasal continuous positive airway pressure (nCPAP) or nasal intermittent positive pressure ventilation (NIPPV) during the first 24 h of life, will be randomized 1:1 to receive IN-REC-SUR-E or LISA surfactant administration. The primary outcome is a composite outcome of death or BPD at 36 weeks’ postmenstrual age. The secondary outcomes are BPD at 36 weeks’ postmenstrual age; death; pulse oximetry/fraction of inspired oxygen; severe intraventricular hemorrhage; pneumothorax; duration of respiratory support and oxygen therapy; pulmonary hemorrhage; patent ductus arteriosus undergoing treatment; percentage of infants receiving more doses of surfactant; periventricular leukomalacia, severe retinopathy of prematurity, necrotizing enterocolitis, sepsis; total in-hospital stay; systemic postnatal steroids; neurodevelopmental outcomes; and respiratory function testing at 24 months of age. Randomization will be centrally provided using both stratification and permuted blocks with random block sizes and block order. Stratification factors will include center and gestational age (24+0 to 25+6 weeks or 26+0 to 27+6 weeks). Analyses will be conducted in both intention-to-treat and per-protocol populations, utilizing a log-binomial regression model that corrects for stratification factors to estimate the adjusted relative risk (RR). Discussion This trial is designed to provide robust data on the best method of surfactant administration in spontaneously breathing preterm infants born at 24+0–27+6 weeks’ gestation affected by RDS and failing nCPAP or NIPPV during the first 24 h of life, comparing IN-REC-SUR-E to LISA technique, in increasing BPD-free survival at 36 weeks’ postmenstrual age of life. Trial registration ClinicalTrials.gov NCT05711966. Registered on February 3, 2023.

Bambara groundnuts (Vigna subterranea (L.) Verdc) provide essential proteins for African farmers, but the yield is largely affected by Alectra vogelii infestation, particularly on nutrient-depleted soils. Laboratory and field investigations were conducted to assess the influence of phosphorus rates and Bambara groundnut genotypes on Alectra vogelii infestation. In the laboratory, a 4 × 26 factorial experiment, varying phosphorus rates (0, 20, 30 and 40 kg ha−1) across 26 genotypes, revealed a significant (p

For many people living at high altitudes for long or short periods of time, hypoxia is a challenge affecting many aspects of the body, including the immune system. Recently, myeloid-derived suppressor cells (MDSCs) have emerged as an immune cell population that plays an important role in several pathological conditions. However, to the best of our knowledge, there are no data regarding the behavior of MDSCs under hypoxic conditions. Therefore, the aim of this study is to investigate the monocytic type (M)- and polymorphonuclear type (PMN)-MDSC ratios in different hypoxic conditions to reveal the relationship between MDSCs and high-altitude hypoxia, as well as to determine whether MDSCs are involved in the regulation of the immune balance under hypoxic conditions as immunosuppressive factors. For the first time, we showed that MDSC abundance varies under different lengths of hypoxic exposure. We found that acute normobaric hypoxia led to an initial increase in the number of M-MDSCs, which decreased within 30 d. Both M- and PMN-MDSC ratios initially decreased under hypobaric hypoxia conditions within 30 d, but after 6 months in the real high altitude environment, M-MDSC ratio increased significantly. In summary, our data suggest that different hypoxic conditions influence MDSCs in mice, thereby contributing to a better understanding of the process of hypoxia adaptation and the occurrence and development of high-altitude disease.

AbstractClimate change is causing significant damage to crop production in the central plateau zone of Rwanda, particularly affecting sorghum, food, and the incomes of smallholder farmers. Understanding farmers’ perceptions and the factors impacting their responses is crucial for improving sorghum production policies and programs. Therefore, a study was conducted to assess sorghum farmers’ perceptions of climate change and the factors determining their adaptation strategies. A multistage sampling method and a cluster random selection were utilized to select 345 respondents from five districts of the study area. The data were analyzed using descriptive statistics and a multivariate probit model. The results showed that 98.8% of farmers were aware of climate change, with deforestation being the main anthropogenic activity causing it. Consequently, 95.7% and 84.3% of farmers experienced grain yield reductions, and over 20 sorghum varieties disappeared. To address these impacts, farmers adopted five adaptation strategies: early maturing sorghum varieties (67%), adjusting planting dates (50.1%), drought-tolerant varieties (46.7%), soil conservation practices (38.3%), and crop diversification (32.8%). The multivariate probit model results showed the age and literacy level of the household head, access to extension services, access to information, access to credit, farming experience, and land size as the important factors influencing at least one of the climate change adaptation strategies. The study concluded that sorghum farmers are aware of the impacts of climate change and are acting to address its negative effects. The results suggest that the government and stakeholders should support farmers in strengthening their adaptation strategies for sustainable sorghum production.

Background: Fetal fibrinogen is a variant present in neonates. Blood products used in neonates are tailored for adults and do not seamlessly integrate into neonatal clots. Increased sialic acid content has been found in fetal fibrinogen compared with adult fibrinogen. However, the extent or location of sialic acids on fibrinogen remains unknown. Objectives: To investigate differences in glycosylation and sialic acid content between fetal and adult fibrinogen. Methods: Glycans were eluted from human cord blood-isolated fetal fibrinogen and commercially available adult fibrinogen using filter-aided N-linked glycan separation. A α, B β, and λ chains were isolated using sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and in-gel enzymatic digestion was performed. Infrared matrix-assisted laser desorption electrospray ionization mass spectrometry was used for analysis. Results: In total, 39 and 22 glycans were detected in fetal and adult fibrinogen, respectively. Fetal fibrinogen glycans were most abundant in the lower molecular weight range

ABSTRACT Pinus sylvestris var. mongolica plays a crucial role in the ecological restoration and industrial raw material production of arid and semiarid regions in northern China. The widespread degradation of its near‐mature plantation (over 30 years) is a significant concern, having been a topic of interest in recent decades. In this study, the genetic diversity and population genetic structure were assessed using 12 simple sequence repeat (SSR) markers within 11 native provenance populations and eight plantation populations. Additionally, variations in eight morphological traits of their offspring were evaluated at three sites in northern China. The results revealed high genetic diversity and weak genetic differentiation among the native provenance populations. The mean number of alleles (Na), allelic richness (Ar), expected heterozygosity (He), and Shannon–Wiener diversity index (I) were 5.492, 4.679, 0.550, and 1.120, respectively, and the genetic differentiation coefficient (FST) was 0.022. Significant population effects of tree height and height to live crown base (HCB), as well as interactions of population with site and block within site, were observed in tree height, HCB, stem diameter at breast height (DBH), stem volume (VOL), crown shape (CS), and disease grade (DG). The genetic diversity parameters based on SSR markers and breeding values of tree height, DBH, HCB, VOL, and stem form (SF) of plantation populations were found to be lower than those of native provenance populations. Significant positive correlations were identified between the mean effective number of alleles per locus (Ne) and VOL as well as He and crown width (CW). Furthermore, the maximum temperature of the warmest month (BIO5) and the silt content (T_SILT) were identified as significant factors influencing genetic diversity parameters and morphological variation, respectively. The findings provide scientific support for the reduction of plantation degradation, the effective restoration, and the sustainable management of forests for this species.