Search

Your search keyword '"Amy Riddle"' showing total 6 results
Start Over Author "Amy Riddle"
6 results on '"Amy Riddle"'

1. Regional citrate anticoagulation 'non-shock' protocol with pre-calculated flow settings for patients with at least 6 L/hour liver citrate clearance

Author

Lenar Yessayan, Ryann Sohaney, Vidhit Puri, Benjamin Wagner, Amy Riddle, Sharon Dickinson, Lena Napolitano, Michael Heung, David Humes, and Balazs Szamosfalvi

Subjects
Veno-venous hemodiafiltration, CKRT, Citrate anticoagulation, Hypocalcemia, Personalized calcium dosing, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract Background Regional citrate anticoagulation (RCA) for the prevention of clotting of the extracorporeal blood circuit during continuous kidney replacement therapy (CKRT) has been employed in limited fashion because of the complexity and complications associated with certain protocols. Hypertonic citrate infusion to achieve circuit anticoagulation results in variable systemic citrate- and sodium load and increases the risk of citrate accumulation and hypernatremia. The practice of “single starting calcium infusion rate for all patients” puts patients at risk for clinically significant hypocalcemia if filter effluent calcium losses exceed replacement. A fixed citrate to blood flow ratio, personalized effluent and pre-calculated calcium infusion dosing based on tables derived through kinetic analysis enable providers to use continuous veno-venous hemo-diafiltration (CVVHDF)-RCA in patients with liver citrate clearance of at least 6 L/h. Methods This was a single-center prospective observational study conducted in intensive care unit patients triaged to be treated with the novel pre-calculated CVVHDF-RCA “Non-shock” protocol. RCA efficacy outcomes were time to first hemofilter loss and circuit ionized calcium (iCa) levels. Safety outcomes were surrogate of citrate accumulation (TCa/iCa ratio) and the incidence of acid-base and electrolyte complications. Results Of 53 patients included in the study, 31 (59%) had acute kidney injury and 12 (22.6%) had the diagnosis of cirrhosis at the start of CVVHDF-RCA. The median first hemofilter life censored for causes other than clotting exceeded 70 h. The cumulative incidence of hypernatremia (Na > 148 mM), metabolic alkalosis (HCO3- > 30 mM), hypocalcemia (iCa 1.5 mM) were 1/47 (1%), 0/50 (0%), 1/53 (2%), 1/53 (2%) respectively and were not clinically significant. The median (25th–75th percentile) of the highest TCa/iCa ratio for every 24-h interval on CKRT was 1.99 (1.91–2.13). Conclusions The fixed citrate to blood flow ratio, as opposed to a titration approach, achieves adequate circuit iCa (

Published
2021
Full Text
View/download PDF

2. Acceleration of Coronal Mass Ejection Plasma in the Low Corona as Measured by the Citizen CATE Experiment

Author

Matthew J Penn, Robert Baer, Donald Walter, Michael Pierce, Richard Gelderman, Andrei Ursache, David Elmore, Adrianna Mitchell, Sarah Kovac, Honor Hare, Myles McKay, Logan Jensen, Zachary Watson, Mike Conley, Lynn Powers, Marianna Lazarova, Joseph Wright, David Young, Fred Isberner, C. Alexandra Hart, N. R. Sheeley, Debbie Penn, Kate Allen-Penn, Bruce Alder, Ryan Alder, Geri Hall-Conley, David Gerdes, Katherine Weber, Jeffrey Johnson, Gerald Matzek, Steven Somes, Rob Sobnosky, Robert McGowen, Michael Meo, Damani Proctor, Charlie Wessinger, Jeannine Schilling, Jay Kerr, Alexander Beltzer-Sweeney, Alex Falatoun, David Higgins, Grady Boyce, Jared Hettick, Philip Blanco, Scott Dixon, Sepehr Ardebilianfard, Pat Boyce, Richard Lighthill, Denese Lighthill, David Anderson, Mine Anderson, Thomas Schad, Sonna Smith, Declan Jensen, Anthony Allen, Donavan Smith, Gage Brandon, Joe Earp, Jane Earp, Bob Blair, Chuck F. Claver, Jennifer A. Claver, Ryan H. Claver, Danielle Hoops, Esteban Rivera, Llanee Gibson, Martin Hiner, Rein Lann, Shaedyn Miller, Burton Briggs, Karan Davis, Brian Jackson, Kaleb Kautzsch, Wesley Sandidge, Russell Lucas, Duane Gregg, Julia Kamenetzky, Tiffany Rivera, Joe Shaw, Bryan Scherrer, Dylan Sandbak, Richard McFate, Wilson Harris, Zachery Brasier, Stephen McNeil, Jack Jensen, Makai Jensen, Mason Moore, Alexandria Temple, Thomas Vanderhorst, Richard Kautz, Orion Bellorado, LaVor R Jenkins, Corey Pantuso, Marley Carey, Josh Byrnes, Kyle Scholtens, Julian Web, Brain Baker, Katie Barngrover, Drew Hathaway, Kallen Smith, Kellyn Chandler, Lydia Hinkle, Ione Chandler, Galen Gisler, Jack Benner, Madison Mas, Maya Rogers, Prescott Moore, Elijah Pelofske, Stephen Gulley, Beth Short, Isabel Crooker, Jennifer Hammock, Katsina Cardenas, Kateri Cardenas, Jennifer Wellman, Mark Roy, Joe Meyer, Jalynne Brough, Kameron Brough, Tim Nelson, Zack Nelson, Caleb Russell, Theresa Bautz, Eric Weitzel & Team, Michele Wistisen, Shae Aagard, Zachary Whipps, Logan Neuroth, Dawson Poste, Connor Worthen, Sanjay Gosain, Mark Steward, Vanshita Gosain, Ruchi Gosain, Janet Jorgensen, Eleanor Doucette, Reba Doucette, Elliott Iwen, Alexus Cochran, James Stith, Doug Scribner, Austen Kenney, Kolby Pisciotti, Irene Pease, Samuel Cynamon, Charles Cynamon, Dawn Cynamon, Bart Tolbert, Jean A. Dupree, Jeremy Weremeichik, Nathan Pindell, Kristen Stives, Thomas K Simacek, Yolanta G Simacek, Anne L. Simacek, Wayne Boeck, Andreea Boeck, Austin Ryan, Gabriel Wierzorec, Dimitri Klebe, Bryan Costanza, Arnie Cerny, Trevor Schmale, Tessa Hoffman, Sam Streeter, Jack Erickson, Michele McClellan, Ella Erickson, Brynn Brettell, Savannah Shoffner, Emilie McClellan, Julie VanVoorhis, Cole Bramhall, Daniel Stelly, Bentley Bee, Bruno Acevedo, Madison Kroeger, Ben Trumpenski, Nolan Sump, Liam Brook, Jagert Ernzen, Jessica Lewis, Ryan Maderak, Charles Kennedy, David Dembinski, Rita Wright, Michael Foster, Mohammad Ahmadbasir, Monty Laycox, James Foster, Ethan Orr, Ashley Staab, Angela Speck, Sean Baldridge, Lucy Kegley, Jordan Bavlnka, Thomas Ballew, Bruce Callen, Gregory Ojakangas, Mark Bremer, Maryanne Angliongto, Mark Redecker, Chris Bremer, Peggy Hill, Michael Rodgers, Jordan Duncan, Sam Fincher, Ben Nielsen, Samantha Hasler, Taylor Shivelbine, Tyler Howard, Chris Midden, Sean Patrick, Kerry Glenn, Chris Mandrell, Kyle Dawson, Margaret Cortez, Alyssa Levsky, Dinuka Gallaba, Mason Perrone, Jasmyn Taylor, Padma A. Yanamandra-Fisher, Howard Harper, Lindsay Adams, Michaela Springer, BillyJoe Menard, Dylan Boggs, Caitlin Lynch, Jacob Watson, Andi York, David Matthews, Kiley Brown, Dylan Garrison, Jonathan Mangin, Isaac Mangin, Jennifer Birriel, Ignacio Birriel, Capp Yess, Jesse Anderson, Ethan Caudill, Allyn Smith, Spencer Buckner, Russ Longhurst, Ben Fagan, Christian Nations, Jeffrey DiMatties, Patricia Thompson, David Garrison, Thomas Garrison, William Garrison, Mary Kidd, Maria Baker, Mary-Beth Ledford, Amy Winebarger, Michael Freed, Morgyn Church, Jim Dickens, Bob Anderson, Ned Smith, Lynne Dorsey, Doug Justice, Daniel Zavala, Zach Stockbridge, Sean Brittain, Stanley Jensen, Harrison Leiendecker, Erin Thompson, Michelle Deady, Kelly Quinn-Hughes, David Slimmer, Valerie Granger, Michael LaRoche, Serena Hill LaRoche, Rachel Manspeaker, Peter Nguyen, Daniel Smith, Jim Payne, Jerry Zissett, Arianna M. Roberts, Gabrielle W. Roberts, Harrison Roberts, Amy Riddle, Corina Ursache, and Elena Ursache

Published
2019
Full Text
View/download PDF

3. Nature and the supernatural in African literature

Author

Amy Riddle

Subjects
Cultural Studies, Anthropology, Philosophy, Supernaturalism, Representation (arts), Naturalism, Realism, Epistemology
Abstract

This essay examines the relationship between literary naturalism and supernaturalism, with an emphasis on the latter. The supernatural genre, a common avenue of representation in African cultural p...

Published
2020

4. Regional citrate anticoagulation 'non-shock' protocol with pre-calculated flow settings for patients with at least 6 L/hour liver citrate clearance

Author

Michael Heung, Amy Riddle, Sharon Dickinson, Lenar Yessayan, Balazs Szamosfalvi, David Humes, Ryann Sohaney, Lena M. Napolitano, Vidhit Puri, and Benjamin Wagner

Subjects
Male, Nephrology, medicine.medical_specialty, CKRT, Continuous Renal Replacement Therapy, Critical Care, 030232 urology & nephrology, Metabolic alkalosis, Veno-venous hemodiafiltration, 030204 cardiovascular system & hematology, Hematocrit, Citric Acid, law.invention, 03 medical and health sciences, 0302 clinical medicine, Clinical Protocols, law, Internal medicine, Humans, Medicine, Cumulative incidence, Prospective Studies, Citrate anticoagulation, Aged, Calcium metabolism, Hypocalcemia, medicine.diagnostic_test, business.industry, Research, Acute kidney injury, Anticoagulants, Middle Aged, medicine.disease, Intensive care unit, Diseases of the genitourinary system. Urology, Solutions, Liver, Anesthesia, Personalized calcium dosing, Female, RC870-923, Hypernatremia, business, Kidneys, Artificial
Abstract

Background Regional citrate anticoagulation (RCA) for the prevention of clotting of the extracorporeal blood circuit during continuous kidney replacement therapy (CKRT) has been employed in limited fashion because of the complexity and complications associated with certain protocols. Hypertonic citrate infusion to achieve circuit anticoagulation results in variable systemic citrate- and sodium load and increases the risk of citrate accumulation and hypernatremia. The practice of “single starting calcium infusion rate for all patients” puts patients at risk for clinically significant hypocalcemia if filter effluent calcium losses exceed replacement. A fixed citrate to blood flow ratio, personalized effluent and pre-calculated calcium infusion dosing based on tables derived through kinetic analysis enable providers to use continuous veno-venous hemo-diafiltration (CVVHDF)-RCA in patients with liver citrate clearance of at least 6 L/h. Methods This was a single-center prospective observational study conducted in intensive care unit patients triaged to be treated with the novel pre-calculated CVVHDF-RCA “Non-shock” protocol. RCA efficacy outcomes were time to first hemofilter loss and circuit ionized calcium (iCa) levels. Safety outcomes were surrogate of citrate accumulation (TCa/iCa ratio) and the incidence of acid-base and electrolyte complications. Results Of 53 patients included in the study, 31 (59%) had acute kidney injury and 12 (22.6%) had the diagnosis of cirrhosis at the start of CVVHDF-RCA. The median first hemofilter life censored for causes other than clotting exceeded 70 h. The cumulative incidence of hypernatremia (Na > 148 mM), metabolic alkalosis (HCO3- > 30 mM), hypocalcemia (iCa 1.5 mM) were 1/47 (1%), 0/50 (0%), 1/53 (2%), 1/53 (2%) respectively and were not clinically significant. The median (25th–75th percentile) of the highest TCa/iCa ratio for every 24-h interval on CKRT was 1.99 (1.91–2.13). Conclusions The fixed citrate to blood flow ratio, as opposed to a titration approach, achieves adequate circuit iCa (

Published
2021

5. Regional Citrate Anticoagulation Protocol for Patients with Presumed Absent Citrate Metabolism

Author

Ryann Sohaney, Lena M. Napolitano, Sharon Dickinson, Amy Riddle, Balazs Szamosfalvi, Vidhit Puri, David Humes, Benjamin Wagner, Lenar Yessayan, and Michael Heung

Subjects
Adult, medicine.medical_specialty, Cirrhosis, 030232 urology & nephrology, Urology, Metabolic alkalosis, Original Investigations, Citric Acid, 03 medical and health sciences, 0302 clinical medicine, Interquartile range, Renal Dialysis, Intensive care, medicine, Humans, Prospective Studies, Blood Coagulation, Calcium metabolism, business.industry, Anticoagulants, 030208 emergency & critical care medicine, General Medicine, medicine.disease, Shock (circulatory), Hypernatremia, medicine.symptom, business, Hypophosphatemia
Abstract

BACKGROUND: Regional citrate anticoagulation (RCA) is not recommended in patients with shock or severe liver failure. We designed a protocol with personalized precalculated flow settings for patients with absent citrate metabolism that abrogates risk of citrate toxicity, and maintains neutral continuous KRT (CKRT) circuit calcium mass balance and normal systemic ionized calcium levels. METHODS: A single-center prospective cohort study of patients in five adult intensive care units triaged to the CVVHDF-RCA “Shock” protocol. RESULTS: Of 31 patients included in the study, 30 (97%) had AKI, 16 (52%) had acute liver failure, and five (16%) had cirrhosis at the start of CKRT. The median lactate was 5 mmol/L (interquartile range [IQR], 3.2–10.7), AST 822 U/L (IQR, 122–2950), ALT 352 U/L (IQR, 41–2238), total bilirubin 2.7 mg/dl (IQR, 1.0–5.1), and INR two (IQR, 1.5–2.6). The median first hemofilter life censored for causes other than clotting exceeded 70 hours. The cumulative incidence of hypernatremia (Na >148 mM), metabolic alkalosis (HCO3- >30 mM), and hypophosphatemia (P0.75 minimizes the risk of citrate toxicity even in patients with absent citrate metabolism. Precalculated, personalized dosing of the initial Ca-infusion rate from a table on the basis of the patient’s albumin level and the filter effluent flow rate maintains neutral CKRT circuit calcium mass balance and a normal systemic iCa level.

Published
2020

6. Acceleration of Coronal Mass Ejection Plasma in the Low Corona as Measured by the Citizen CATE Experiment

Author

Capp Yess, Sepehr Ardebilianfard, Charlie Wessinger, Zach Stockbridge, Valerie Granger, James C. Dickens, Jared Hettick, Michael Freed, Michael Meo, Jagert Ernzen, James Stith, Caitlin Lynch, Martin Hiner, Rita Wright, Charles Cynamon, Bruno Acevedo, Jennifer Hammock, Joseph Wright, Donald K. Walter, Morgyn Church, Charles Kennedy, Lydia Hinkle, Samantha Hasler, Zachary Watson, Harrison Roberts, Harrison Leiendecker, Nolan Sump, Isabel Crooker, Rob Sobnosky, Jennifer Wellman, Thomas A. Schad, C. Alexandra Hart, Bob Anderson, Alexandria Temple, Llanee Gibson, Tim Nelson, Brynn Brettell, Sonna Smith, Mary-Beth Ledford, LaVor R Jenkins, Bruce Alder, Mark Roy, Dimitri I. Klebe, Ione Chandler, Sam Fincher, Rein Lann, Lynne Dorsey, Doug Scribner, Emilie McClellan, Jesse Anderson, Thomas K Simacek, J. Kamenetzky, Samuel Cynamon, Margaret Cortez, Bryan Scherrer, Kolby Pisciotti, Ruchi Gosain, Dylan Sandbak, Chris Mandrell, Richard L. Kautz, Andi York, Dawn Cynamon, Arnie Cerny, Jalynne Brough, Julie VanVoorhis, Robert McGowen, Ignacio Birriel, Daniel Zavala, Jacob Watson, Chris Bremer, Sanjay Gosain, David Higgins, Jack Erickson, Ned Smith, Lynn Powers, Beth Short, Jeff A. Johnson, Jerry Zissett, Mason Moore, Ryan Alder, BillyJoe Menard, David Dembinski, Mason Perrone, Kyle Scholtens, Elena Ursache, Karan Davis, Michael LaRoche, Jennifer J. Birriel, Ben Nielsen, Jessica Lewis, Jay Kerr, Thomas Vanderhorst, Isaac Mangin, Thomas Garrison, Mike Conley, Zachary Whipps, Wilson Harris, Bob Blair, Mark Steward, Anne L. Simacek, Connor Worthen, N. R. Sheeley, Patricia Thompson, Kelly D. Quinn-Hughes, Grady Boyce, Drew Hathaway, Kiley Brown, Andreea Boeck, David Young, Janet Jorgensen, Padma A. Yanamandra-Fisher, Liam Brook, Peter Nguyen, Doug Justice, Alex Falatoun, Alexus Cochran, Cole Bramhall, Michele McClellan, Monty Laycox, Tiffany A. Rivera, Mark Redecker, Ethan Caudill, D. W. Gerdes, Austen Kenney, Orion Bellorado, Arianna M. Roberts, Gage Brandon, Amy Riddle, Jordan Bavlnka, Richard Lighthill, Gerald Matzek, Jack Benner, Katsina Cardenas, Trevor Schmale, Kameron Brough, Bart Tolbert, Theresa Bautz, Russell Lucas, Chuck F. Claver, Christian Nations, Gabriel Wierzorec, Anthony Allen, Russ Longhurst, Shae Aagard, Chris Midden, Duane Gregg, Gregory W. Ojakangas, Maria Baker, Jeannine Schilling, Elijah Pelofske, Angela Speck, Corina Ursache, Michael L. Rodgers, Jack Jensen, Gabrielle W. Roberts, Wesley Sandidge, Vanshita Gosain, Kaleb Kautzsch, Taylor Shivelbine, Ashley Staab, Kellyn Chandler, Fred Isberner, Sam Streeter, Madison Kroeger, Lindsay Adams, Yolanta G Simacek, Ben Trumpenski, Maryanne Angliongto, Dawson Poste, Adrianna Mitchell, Robert Baer, Stephen Gulley, Corey Pantuso, Erin Thompson, Daniel M. Smith, Joe Meyer, Honor Hare, Alyssa Levsky, Zack Nelson, Mine Anderson, Sean D. Brittain, Jordan Duncan, Myles McKay, Jeffrey DiMatties, Marianna Lazarova, Kyle Dawson, Bruce W. Callen, Thomas Ballew, David G. Anderson, Dylan Garrison, Julian Web, Makai Jensen, Pat Boyce, Denese Lighthill, Ryan M. Maderak, David Elmore, Michele Wistisen, Kerry Glenn, William Garrison, Howard Harper, Michael J. Pierce, Eleanor Doucette, David Garrison, Richard McFate, Michael Foster, Jonathan Mangin, Geri Hall-Conley, Lucy Kegley, Katherine G. Weber, Sarah Kovac, Brian Jackson, David Matthews, Jennifer A. Claver, Spencer Buckner, Brain Baker, Ethan Orr, Kallen Smith, Dylan Boggs, Savannah Shoffner, Ben Fagan, Serena Hill LaRoche, Kateri Cardenas, Logan Jensen, Maya Rogers, Philip Blanco, Galen Gisler, Zachery Brasier, Jean A. Dupree, Mark Bremer, Jeremy M. Weremeichik, Reba Doucette, Andrei Ursache, Sean Baldridge, James Foster, Michaela Springer, Richard Gelderman, Scott Dixon, Alexander Beltzer-Sweeney, Shaedyn Miller, Daniel Stelly, M. J. Penn, Wayne Boeck, Eric Weitzel Team, Caleb Russell, Madison Mas, Dinuka H. Gallaba, Ryan H. Claver, Joe Earp, Danielle Hoops, Prescott Moore, Declan Jensen, Mohammad Ahmadbasir, Amy R. Winebarger, Burton Briggs, Jasmyn Taylor, Irene Pease, Esteban Rivera, Mary Kidd, Tyler V. Howard, Kristen Stives, Joe Shaw, Marley Carey, Debbie Penn, Steven Somes, Nathan Pindell, Kate Allen-Penn, Donavan Smith, S. Jensen, Katie Barngrover, Logan Neuroth, Bryan Costanza, Ella Erickson, Damani Proctor, David Slimmer, Michelle Deady, Josh Byrnes, Jim Payne, Austin Ryan, Stephen McNeil, Sean Patrick, Bentley Bee, Rachel Manspeaker, Jane Earp, Peggy Hill, Elliott Iwen, Tessa Hoffman, and Allyn Smith

Subjects
Physics, Manchester Cancer Research Centre, ResearchInstitutes_Networks_Beacons/mcrc, Astronomy and Astrophysics, Plasma, Astrophysics, 010502 geochemistry & geophysics, 01 natural sciences, Corona, Acceleration, Space and Planetary Science, 0103 physical sciences, Coronal mass ejection, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences
Abstract

The citizen Continental-America Telescopic Eclipse (CATE) Experiment was a new type of citizen science experiment designed to capture a time sequence of white-light coronal observations during totality from 17:16 to 18:48 UT on 2017 August 21. Using identical instruments the CATE group imaged the inner corona from 1 to 2.1 RSun with 1.″43 pixels at a cadence of 2.1 s. A slow coronal mass ejection (CME) started on the SW limb of the Sun before the total eclipse began. An analysis of CATE data from 17:22 to 17:39 UT maps the spatial distribution of coronal flow velocities from about 1.2 to 2.1 RSun, and shows the CME material accelerates from about 0 to 200 km s−1 across this part of the corona. This CME is observed by LASCO C2 at 3.1–13 RSun with a constant speed of 254 km s−1. The CATE and LASCO observations are not fit by either constant acceleration nor spatially uniform velocity change, and so the CME acceleration mechanism must produce variable acceleration in this region of the corona.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results