33 results on '"Amro C"'
Search Results
2. The enigma of incisional hernia prediction unraveled: external validation of a prognostic model in colorectal cancer patients
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Amro, C., Smith, L., Shulkin, J., McGraw, J. R., Hill, N., Broach, R. B., Torkington, J., and Fischer, J. P.
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- 2024
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3. THE ENIGMA OF INCISIONAL HERNIA PREDICTION UNRAVELLED: EXTERNAL VALIDATION OF A PROGNOSTIC MODEL IN COLORECTAL CANCER PATIENTS
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Amro, C, primary, Smith, L, additional, Shulkin, J, additional, Reed McGraw, J, additional, Hill, N, additional, Broach, R B, additional, Torkington, J, additional, and Fischer, J P, additional
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- 2024
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4. Transversus abdominis release with biosynthetic mesh for large ventral hernia repair: a 5-year analysis of clinical outcomes and quality of life
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Messa, C. A., primary, Amro, C., additional, Niu, E. F., additional, Habarth-Morales, T. E., additional, Talwar, A. A., additional, Thrippleton, S., additional, Broach, R., additional, and Fischer, J. P., additional
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- 2023
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5. OC-019 LEVERAGING NATURAL LANGUAGE PROCESSING AND ARTIFICIAL INTELLIGENCE TO LABEL UNSTRUCTURED DATA FOR RISK PREDICTION
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Amro, C, primary, Desai, A, additional, Dattatri, P, additional, Liu, T, additional, Hsu, J Y, additional, Broach, R B, additional, Ungar, L H, additional, and Fischer, J P, additional
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- 2023
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6. OC-113 GENETIC AND BIOLOGIC RISK FACTORS ASSOCIATED WITH HERNIA FORMATION: A SYSTEMATIC REVIEW
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Amro, C, primary, Niu, E F, additional, Deianni, E, additional, Smith, L, additional, Qiu, M, additional, Torkington, J, additional, Broach, R B, additional, Maguire, L H, additional, Damrauer, S M, additional, and Fischer, J P, additional
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- 2023
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7. P-073 RESORBABLE SYNTHETIC VS. BIOLOGIC MESH VENTRAL HERNIA REPAIR IN CONTAMINATED FIELDS
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Amro, C, primary, Niu, E F, additional, Honig, S, additional, Davis, H D, additional, Habarth-Morales, T E, additional, Broach, R B, additional, and Fischer, J P, additional
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- 2023
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8. OC-010 5-YEAR ASSESSMENT OF RESORBABLE BIOSYNTHETIC MESH WITH TRANSVERSE ABDOMINIS RELEASE FOR LARGE VENTRAL HERNIA REPAIR: A LONG-TERM EVALUATION OF CLINICAL OUTCOMES AND QUALITY OF LIFE
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Amro, C, primary, Messa Iv, C A, additional, Niu, E F, additional, Habarth-Morales, T E, additional, Talwar, A A, additional, Thrippleton, S, additional, Broach, R B, additional, and Fischer, J P, additional
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- 2023
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9. OC-081 DIASTASIS RECTI REPAIR – DEVELOPMENT OF A PATIENT REPORTED OUTCOME MEASURE THROUGH QUALITATIVE ASSESSMENT
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Amro, C, primary, Mcauliffe, P B, additional, Niu, E F, additional, Bilger, A, additional, Broach, R B, additional, Rendle, K A, additional, and Fischer, J P, additional
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- 2023
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10. Abdominoplasty With Umbilical Hernia Repair: A Long-term Comparative Analysis of Clinical Outcomes.
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Messa Iv CA, Davis HD, Habarth-Morales TE, Amro C, Broach RB, and Fischer JP
- Abstract
Background: The risks and benefits of performing small fat-containing ventral or umbilical hernia repair (HR) during cosmetic abdominoplasty remains a reconstructive and aesthetic challenge for plastic surgeons., Objectives: This study aimed to compare clinical outcomes in patients undergoing abdominoplasty with concurrent HR and abdominoplasty alone., Methods: Retrospective review of patients undergoing abdominoplasty with and without a concurrent HR from January 2015- June 2022 was performed. Patients were stratified by concurrent HR. All hernia patients underwent primary fascial repair, without the use of mesh. Demographics, surgical site occurrences (SSO) and cosmetic complications, including delayed healing and necrosis were assessed. Multivariate analysis was used to compare association of umbilical hernia repair with clinical outcomes., Results: One hundred and six patients underwent abdominoplasty, 68 (64%) had concurrent HR. No significant difference in demographics was identified between groups including mean BMI (HR=27.2 kg/m2 and No HR= 26.3 kg/m2, P=0.73), and number of previous open hernia repairs (P=0.09). After a mean follow-up of 1.5 years, hernia recurrence rate was 1.4% (n=1), with a time to hernia recurrence of 12.2 months. After controlling for confounders, there was no difference in risk of SSO (OR 1.02 [0.31-3.36] P=0.978), cosmetic complications (OR 0.80 [0.14-4.57] P=0.805), procedure length (-21.5 minutes [-46.92-22.93] P=0.501), readmissions (2.8% vs. 0%, P=0.336), or reoperations (8.8% vs. 10%, P=0.766), compared to patients who underwent abdominoplasty alone., Conclusions: Abdominoplasty with concurrent HR can be performed safely and effectively, with no increase in adverse outcomes or cosmetic complications. The benefit of performing mesh-free HR with abdominoplasty can achieve an enhanced aesthetic outcome and reduce long-term abdominal wall morbidity., (© The Author(s) 2024. Published by Oxford University Press on behalf of The Aesthetic Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
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- 2024
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11. Marijuana and Its Implications in Breast Reduction Surgery Outcomes and Quality of Life: A Matched Analysis.
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Ewing JN, Amro C, Chang A, Gala Z, Lemdani MS, Broach RB, Fischer JP, Serletti JM, and Azoury SC
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Background: With marijuana use on the rise, its influence on surgical outcomes, particularly for breast reduction, warrants investigation. This study aims to clarify marijuana's effects on breast reduction surgery outcomes, given its limited research focus despite potential perioperative implications., Methods: A retrospective review was conducted from 2016 to 2022 of patients with/without marijuana use undergoing breast reduction. Propensity score-matching considered age, body mass index, ptosis, and breast tissue mass. Patient demographics, clinical attributes, and postoperative details were analyzed. Quality-of-life (QoL) changes were gauged using pre- and postoperative BREAST-Q., Results: Of 415 patients who underwent breast reduction, 140 patients documented marijuana use. After propensity matching, a total of 108 patients (54 marijuana users versus 54 nonusers) were analyzed. The average age was 39 years ± 12 and body mass index 30.1 kg/m
2 ± 5.3. There were no differences between the 2 groups in comorbidities, breast symmetry, excision patterns, pedicle use, or drain count ( P > 0.05). Furthermore, surgical outcomes including surgical site occurrences, scarring, pain levels, hypersensitivity, or sensation loss were comparable between the groups ( P > 0.05). There were also no differences in number of readmissions, reoperations, or emergency department visits ( P > 0.05). Both groups showed enhanced postoperative QoL, regardless of marijuana usage., Conclusions: This study indicates that marijuana use does not significantly impact breast reduction surgery outcomes. Comparable surgical results and postoperative QoL improvements were observed in both marijuana users and nonusers. This study provides surgeons with the knowledge to offer more informed patient counseling regarding the implications of marijuana use in relation to breast reduction procedures., Competing Interests: Dr. John P. Fischer has received consulting payments from 3M, AbbVie, Baxter, Becton-Dickinson, WL Gore, and Integra Life Sciences. He has received research support from the National Institutes of Health. Dr. Said C. Azoury has received consulting payments from GORE, RTI and Integra Life Sciences. The other authors have no financial interest to declare in relation to the content of this article. Disclosure statements are at the end of this article, following the correspondence information., (Copyright © 2024 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.)- Published
- 2024
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12. Unplanned 180-day Readmissions and Healthcare Utilization After Immediate Breast Reconstruction for Breast Cancer.
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Rios-Diaz AJ, Habarth-Morales T, Isch EL, Amro C, Davis HD, Broach R, Jenkins M, Fischer JP, and Serletti JM
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Purpose: To assess the burden of post-discharge healthcare utilization given by readmissions beyond 30-days following immediate breast reconstruction (IBR) nationwide., Methods: Women with breast cancer who underwent mastectomy and concurrent IBR (autologous and implant-based) were identified within the 2010-2019 Nationwide Readmission Database. Cox proportional hazards and generalized linear regression controlling for patient- and hospital-level confounders were used to determine factors associated with 180-day unplanned readmissions and incremental hospital costs, respectively., Results: Within 180 days 10.7% of 100,942 women were readmitted following IBR.. Readmissions tended to be publicly insured (30.8% vs. 21.7%, P<0.001), and multimorbid (Elixhauser comorbidity index >2 31.6% vs. 19.6%, P<0.001) compared to non-readmitted patients. There were no differences in readmission rates amongst types of IBR (tissue expander 11.2%, implant 10.7%, autologous 10.8%; P>0.69). Of all readmissions, 40% occurred within 30 days and 21.7% in a different hospital, and 40% required a major procedure in the operating room. Infection was the leading cause of readmissions (29.8%). In risk-adjusted analyses, patients with carcinoma in situ, publicly insured, low socioeconomic status, and higher comorbidity burden were associated with increased readmissions (all P<0.05). Readmissions resulted in additional $8,971.78 (95% CI: $8,537.72-9,405.84, P<0.001) in hospital costs which accounted for 15% of the total cost of immediate breast reconstruction nationwide., Conclusion: The majority of inpatient healthcare utilization given by readmissions following mastectomy and IBR occurs beyond the 30-day benchmark. There is evidence of fragmentation of care as a quarter of readmissions occur in a different hospital and over one-third require major procedures. Mitigating postoperative infectious complications could result in the highest reduction of readmissions., Competing Interests: The authors declare that they have no conflict of interest., (Thieme. All rights reserved.)
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- 2024
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13. Reevaluation of Recipient Vessel Selection in Breast Free Flap Reconstruction.
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Lemdani MS, Crystal DT, Ewing JN, Gala Z, Amro C, Azoury SC, Broach RB, Rhemtulla IA, and Serletti JM
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- Humans, Female, Retrospective Studies, Middle Aged, Adult, Postoperative Complications epidemiology, Anastomosis, Surgical methods, Aged, Microsurgery methods, Graft Survival, Breast Neoplasms surgery, Free Tissue Flaps blood supply, Free Tissue Flaps transplantation, Mammaplasty methods, Mammary Arteries surgery
- Abstract
Background: Current consensus has established the internal mammary vessels (IMV) over the thoracodorsal vessels (TDV) as the preferred recipients for microvascular breast reconstruction due to their superior flow rates and long-established outcomes. Yet, there are occurrences where the IMVs are not reliable and may subsequently prompt intraoperative decision-making. Several options exist, including the contralateral IMVs, thoracoacromial vessels, and TDVs. The appropriate sequence for vessel choice is not universally agreed upon. This study reevaluates the TDVs to highlight their viability as a second-line intraoperative alternative to the IMV and provide reference to the straightforward dissection required for harvest., Methods: A retrospective, single-institution, breast-level analysis examining 4754 breast free flaps from 2978 patients undergoing bilateral free flap reconstruction was conducted. Postoperative complications within 180 days were evaluated, and cohorts based on anatomic anastomosis (IMV vs. TDV) were created to compare outcomes. Subanalysis was conducted based on flap laterality as well as whether a flap was planned or converted intraoperatively., Results: Of 4754 breast free flaps, 4269 (89.8%) used the IMV while 485 (10.2%) used the TDV. Most complication rates between the TVD and IMV were not significantly different. Rates of flap loss were 1.0% and 1.2% for the IMV and TDV anastomosis (p = 0.59). IMV and TDV anastomosed flaps experienced similar rates of fat necrosis (6.3% vs. 6.2%, p = 0.915). However, multivariable analysis of all breasts regardless of laterality showed that skin necrosis was significantly less likely in TDV breasts (OR 0.45, 95% CI 0.29-0.71, p < 0.001)., Conclusions: Given the relative similarity in cohort outcomes, TDV anastomosis can be considered a viable alternative to the IMV when the IMV is unavailable or technically disadvantageous. The TDV artery remains a robust and reliable option in the present-day plastic surgeon's repertoire for breast reconstruction., (© 2024 The Author(s). Microsurgery published by Wiley Periodicals LLC.)
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- 2024
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14. Analysis of the microsurgery fellowship match: 2019-2022 update.
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McGraw JR, Sulkar RS, Amro C, Gala Z, Mehrara BJ, Wong AK, Kovach SJ 3rd, Matros E, and Azoury SC
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- Humans, United States, Education, Medical, Graduate, Microsurgery education, Fellowships and Scholarships statistics & numerical data, Internship and Residency
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Background: A recent analysis of microsurgery fellowship match data published in 2019 demonstrated increased competition for available positions. With growing opportunities in the field, the authors hypothesize that the landscape for both applicants and programs has become more competitive. The aim of this study is to compare two periods of match data to inform residents and programs in microsurgery., Methods: Microsurgery fellowship match data was obtained from the San Francisco Match with approval by the American Society for Reconstructive Microsurgery for the years 2014-2022. Data were stratified into the categories of 2016-2018 and 2019-2022. Parameters assessed included: program and position fill rates, match rates, and in-service examination percentiles. Data were analyzed using Pearson's Chi-square tests and unpaired t-tests., Results: The median number of participating programs and positions increased to 29 and 47 in 2019-2022, compared with 23 and 40 in 2016-2018. This coincided with a decrease in the number of applicants per position (1.3 [52-40] vs. 1.1 [50-47], p = .45). There was a significant increase in the match rate between groups (67.8% vs. 80.2%, p = .007). Recently, 2022 saw the lowest position fill rate on record, at 75.4% (40 of 53 positions filled), down from 85.3% (35 of 41) in 2018 (p = .35) and 95.6% (43 of 45) in 2019 (p = .006). Mean in-service examination percentiles for successfully matched applicants did not differ between (2016-2018) and (2019-2022) applicants., Conclusion: Recent years have seen a rise in the number of microsurgery fellowship training programs with a decline in the number of applicants. Accordingly, there has been an increased match rate for prospective applicants. Despite this, a pool of unmatched applicants and unfilled positions with training opportunities still remain. The reasons for which are likely multifactorial., (© 2024 Wiley Periodicals LLC.)
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- 2024
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15. Balancing the Scales: Caution in Reduction Mammaplasty Recommendations for Obesity Class III Patients.
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Ewing JN, Niu EF, Amro C, Gala Z, Lemdani MS, Chang AE, Broach RB, Serletti JM, and Fischer JP
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- Humans, Female, Adult, Middle Aged, Retrospective Studies, Treatment Outcome, Postoperative Complications epidemiology, Postoperative Complications etiology, Mammaplasty methods, Quality of Life, Body Mass Index, Obesity surgery, Obesity complications
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Introduction: The prevalence of obesity has risen worldwide, posing a problem to surgeons as obesity is a well-known risk factor for surgical outcomes. While prior studies have suggested performing reduction mammaplasty (RM) in patients with obesity, the variance in outcomes and quality of life (QoL) for obesity classes are ill-defined. We investigated whether obesity classes should be considered for RM by examining the surgical outcomes and QoL across different weight classes, aiming to pinpoint when outcomes become less favorable., Methods: Patients undergoing RM by nine surgeons from 2016 to 2022 were included. Body mass index (BMI) cohorts were formed according to the Center for Disease Control and Prevention (CDC) guidelines: Healthy (18.5-24.9 kg/m 2 ), overweight (25-29.9 kg/m 2 ), obesity class I (30-34.9 kg/m 2 ), II (35-39.9 kg/m 2 ), and III (>40 kg/m 2 ). QoL was assessed by comparing preoperative and postoperative BREAST-Q scores within cohorts. A comparison analysis was performed between weight classes., Results: A total of 461 RM patients were identified (healthy: 83, overweight: 178, I: 142, II: 39, III: 19). Percentage of Black patients, procedure length, weight of tissue removed, and inferior pedicle technique all significantly increased as BMI increased ( P < 0.001). Higher BMI cohorts, especially class III, had significantly higher rates of surgical site infections (healthy: 0%, overweight: 1.1%, I: 1.4%, II: 0%, III: 15.8%, P < 0.01), fat necrosis (healthy: 1.2%, overweight: 5.1%, I: 7%, II: 0%, III: 22.2%, P = 0.01), dehiscence (healthy: 3.6%, overweight: 2.8%, I: 2.1%, II: 5.1%, III: 31.6%, P < 0.01), delayed healing (health: 4.8%, overweight: 11.2%, I: 16.9%, II: 28.2%, III: 42.1%, P < 0.01), minor T-point breakdown (healthy: 10.8%, overweight: 15.7%, I: 23.9%, II: 23.1%, III: 52.6%, P = 0.01), and surgical site occurrence requiring procedural intervention (healthy: 6.0%, overweight: 5.6%, I: 6.3%, II: 15.4%, III: 21.1%, P < 0.05). When compared to the other weight classes independently, class III was associated with unfavorable outcomes ( P < 0.05). Significant improvement in average postoperative QoL scores in satisfaction with breast, psychosocial well-being, sexual well-being, and physical well-being were seen in all cohorts except class III ( P < 0.05)., Conclusions: Severe obesity class III patients undergoing RM have a higher yet still acceptable risk profile and should be counseled on the risks despite its improved quality of life., Competing Interests: Conflicts of interest and sources of funding: none declared., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2024
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16. Mesh exposure after ventral hernia repair with onlay biosynthetic mesh: a retrospective review of associated risk factors and management strategies.
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Amro C, Ryan I, Lemdani MS, Bascone CM, McAuliffe PB, Desai AA, McGraw JR, Broach RB, Kovach SJ, and Fischer JP
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- Humans, Middle Aged, Female, Retrospective Studies, Male, Risk Factors, Aged, Adult, Recurrence, Hydroxybutyrates, Postoperative Complications etiology, Absorbable Implants adverse effects, Polyesters, Surgical Mesh adverse effects, Hernia, Ventral surgery, Herniorrhaphy adverse effects
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Background: Although intraperitoneal and retromuscular mesh placement in ventral hernia repair (VHR) are associated with lower recurrence rates, the onlay plane remains a well-established option for certain clinical scenarios. A knowledge gap remains regarding resorbable biosynthetic onlay mesh and mesh exposure. We aim to determine exposure rate, risk factors, and treatment options., Study Design: A single-center, two-surgeon retrospective review was performed examining patients who underwent VHR with onlay, Poly-4-hydroxybutyrate (P4HB) mesh from 2015 to 2021. Demographics, operative characteristics, outcomes, and mesh exposure management were analyzed., Results: Of 346 patients, 15 (4.3%) experienced mesh exposure. The mean age was 53 years and BMI of 33.6 kg/m
2 . Patients were majority ASA class 3 (65%), female (64.2%), and averaged a defect size of 307.9 ± 235.2 cm2 . Independent risk factors included diabetes (AOR = 4.3,CI 1.5-12.5;p < 0.005) and COPD (AOR = 5.2,CI 1.3-21.8;p = 0.02). Mesh exposures were identified as outpatient (20%) or intraoperative (80%). All underwent operative debridement, in which nine were managed with skin reclosure, two with partial closure, and four healed by secondary intention. Five patients required excision of unincorporated mesh. Four patients required further debridement from chronic surgical site occurrences; however, all mesh exposure patents healed after a mean of 260.8 ± 313.2 days and retained original mesh. The recurrence rate was 6.7% for mesh exposure patients., Conclusion: When faced with mesh exposure, resorbable biosynthetic mesh placed in onlay fashion was retained in all patients. Patients with a history of diabetes or COPD have increased risk of mesh exposure and should be counseled., (© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)- Published
- 2024
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17. An Update on the Independent Plastic Surgery Match (2019-2022): Trends, Predictors, and Program Leaders' Perspectives.
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Amro C, Ryan IA, McGraw JR, Broach RB, Kovach SJ, Serletti JM, Butler PD, Janis JE, and Azoury SC
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Background: A previous study by the authors noted a decline in independent plastic surgery residency programs and rising applicant participation. This study provides updates on match trends and influential predictors, and gathers program leaders' views on the future of the independent track., Methods: Match data (2019-2022) were obtained from the San Francisco match after American Council of Educators in Plastic Surgery approval. Variables influencing match success were analyzed, and program leaders were surveyed about desirable applicant traits and program trajectories., Results: From 2019 to 2022, 243 of 428 applicants matched. Programs and positions declined by 10% and 9.5%, respectively. Applicants rose to 42.3%, but match rates fell from 82% to 56%. Osteopathic graduates doubled, whereas international graduates increased to 53.8%. Successful matches were associated with US allopathic medical school graduates, university-affiliated general surgery residencies, eight or more interviews, United States Medical Licensing Examination scores greater than 230, and high post graduate year (PGY)1-3 American Board of Surgery In-service Training Examination scores (PGY1-64.7%, PGY2-61.2%, PGY3-60.7%; P < 0.05). Of surveyed programs, 55.6% aimed to continue running the independent track in the next year. Conversely, 7.4% planned to discontinue in the next year, 22.2% within 2-5 years, 7.4% within the next decade, and 7.4% were unsure., Conclusions: Although support for the independent plastic surgery track remains, program participation diminishes as applicant interest increases, intensifying match challenges. Increasing number of interviews improves match potential. Program leaders display varied commitments, with looming plans for some programs to discontinue offering this track. Applicant evaluation pivots on strong recommendations, research, and test scores., Competing Interests: Jeffrey Janis receives royalties from Thieme and Springer publishing and is a co-founder of the Plastic Surgery Central Application. All the other authors have no financial interest to declare in relation to the content of this article., (Copyright © 2024 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.)
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- 2024
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18. A Longitudinal Evaluation of Collaboration in Plastic Surgery Clinical Research.
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Ewing JN, Lemdani MS, Gala Z, Amro C, Broach RB, Serletti J, and Fischer JP
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Background: Few dedicated, funded clinical research fellowship positions exist in plastic surgery. This study provides insights from an established clinical research fellowship, highlighting its educational impact and confirming the impact of positive institutional support and a collaborative-first approach., Methods: All research fellows within the program from 2008 to 2020 were examined during their year of employment and subsequent 2 years. Internal and external collaboration trends were assessed using PubMed affiliations. Correlation between external collaborations and research impact were examined. Research impact was characterized by publication count, journal impact factor, and journal diversity., Results: Thirty-one research fellows were identified, with a 100% match rate. Four phases of development were identified, and a three-period cycle of productivity was noted to occur every 3 years. A shift toward more external collaborations occurred after 2016 ( P = 0.008). A positive correlation was observed between external collaborations and academic output (r = 0.72, P = 0.004), journal diversity (r = 0.74, P = 0.004), and journal impact (r = 0.63, P < 0.05). Significant growth was observed in the collaborative networks ( P = 0.002), publications ( P = 0.003), journal diversity ( P < 0.001), and research personnel ( P = 0.002)., Conclusions: As a result of our strategic decision to engage collaborators across multiple disciplines, there is discernible improvement in measurable impact, contributing to the growth of our program. Dedicating resources to foster deeper collaborations can enrich the field of plastic surgery research, recognizing that this investment fuels the cycle of productivity, offering promising returns to the future., Competing Interests: Dr. Fischer has received consulting payments from 3M, AbbVie, Baxter, Becton-Dickinson, WL Gore, and Integra Life Sciences. The authors have no financial interest to declare in relation to the content of this article., (Copyright © 2024 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.)
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- 2024
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19. Genetic and biologic risk factors associated with hernia formation: A review.
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Amro C, Niu EF, Deianni E, Smith L, Qiu M, Torkington J, Broach RB, Maguire LH, Damrauer SM, Itani K, and Fischer JP
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- Humans, Risk Factors, Hernia, Inguinal genetics, Incisional Hernia genetics, Incisional Hernia epidemiology, Hernia, Hiatal genetics, Hernia, Hiatal complications, Hernia, Abdominal genetics, Hernia, Abdominal epidemiology, Biomarkers, Genetic Predisposition to Disease
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Background: This systematic review aims to identify genetic and biologic markers associated with abdominal hernia formation., Methods: Following PRIMSA-guidelines, we searched PubMed, MEDLINE, Embase, Scopus, and COCHRANE databases., Results: Of 5946 studies, 65 were selected, excluding parastomal hernias due to insufficient data. For inguinal hernias, five studies unveiled 92 susceptible loci across 66 genes, predominantly linked to immune responses. Eleven studies observed elevated MMP-2 levels, with seven highlighting greater MMP-2 in direct compared to indirect inguinal hernias. One incisional hernia study identified unique gene-expression profiles in 174 genes associated with inflammation and cell-adhesion. In hiatal hernias, several genetic risk loci were identified. For all hernia categories, type I/III collagen ratios diminished., Conclusions: Biological markers in inguinal hernias appears consistent. Yet, the genetic predisposition in incisional hernias remains elusive. Further research to elucidate these genetic and biological intricacies can pave the way for more individualized patient care., Competing Interests: Declaration of competing interest Dr. Fischer has received consulting payments from 3 M, AbbVie, Baxter, Becton-Dickson, WL Gore, and Integra Life Sciences. He has received research support from the National Institutes of Health (NIH). The other authors have no disclosures. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors., (Published by Elsevier Inc.)
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- 2024
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20. Accelerating Fleur-de-lis Panniculectomy with the Absorbable Dermal Stapler-A Study of Efficiency, Aesthetics, and Quality-of-life.
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Amro C, Ryan IA, Lemdani MS, McGraw JR, Schafer S, Broach RB, and Fischer JP
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- Humans, Retrospective Studies, Female, Male, Middle Aged, Adult, Treatment Outcome, Operative Time, Cohort Studies, Absorbable Implants, Suture Techniques instrumentation, Quality of Life, Abdominoplasty methods, Esthetics, Surgical Stapling methods, Surgical Staplers
- Abstract
Background: Fleur-de-lis panniculectomy (FDL), a contouring technique involving vertical and horizontal tissue resections, often involves longer operative times and potential complications. This study assessed operative time, postoperative outcomes, and patient-reported quality of life (PRO) with Insorb
® Absorbable Subcuticular Skin Stapler versus traditional sutures during FDL., Methods: A retrospective review from 2015 to 2022 of FDL patients excluded those with complex concomitant procedures. Demographics, operative details, and surgical outcomes were compared between patients using the dermal stapler and those with suture-only closures., Results: Forty subjects were identified, with 25 (62.5%) in the dermal stapler cohort. The dermal stapler significantly reduced total procedure time (66.76 vs. 125.33 min, p < 0.05). There were no significant differences in surgical site occurrences, aesthetic outcomes, readmissions, or reoperations. Multivariate regression analysis further highlighted the choice of closure technique as an independent predictor of operative time, with traditional sutures indicating a significantly increased operative time compared to using the dermal stapler (AOR 76.53, CI 38.11-114.95, p < 0.001). Regarding PROs, both groups saw improvements across multiple BODY-Q domains, but the dermal stapler group reported greater enhancements (six out of nine domains vs. three for sutures)., Conclusion: The absorbable dermal stapler significantly reduces FDL operative time without increasing wound healing or aesthetic dissatisfaction incidents and maintains comparable quality-of-life improvements to standard suture closure., Level of Evidence Iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors https://link.springer.com/journal/00266 ., (© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)- Published
- 2024
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21. Increased Patient Age as a Risk Factor Following Free Flap Reconstruction after Breast Cancer: A Single Institutional Review of 2,598 Cases.
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Honig SE, Habarth-Morales TE, Davis HD, Niu EF, Amro C, Broach RB, Serletti JM, and Azoury SC
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Background: Autologous breast reconstruction (ABR) after mastectomy is increasing due to benefits over implant-based reconstruction. However, free flap reconstruction is not universally offered to patients of advanced age due to perceived increased perioperative risk., Methods: Patients undergoing free flap breast reconstruction at our institution from 2005 to 2018 were included. Risk-adjusted logistic regression models were fit while controlling for demographic and comorbid characteristics to determine the association of age with the probability of venous thromboembolism (VTE), delayed healing, skin necrosis, surgical site infection (SSI), seroma, hematoma, hernia, and flap loss. Linear predictions from risk-adjusted logistic regression models were used to create spline curves and determine the risk of outcomes associated with age., Results: A cohort of 2,598 patients underwent free flap breast reconstruction in the period examined. The median age was 51 with approximately 9% of patients being 65 or older. Increased age was associated with a greater risk of delayed healing, skin necrosis, and hematoma after surgery. There was no increased risk of medical complications such as VTE or complications such as flap loss, seroma, or SSI., Conclusion: A set age cutoff for patients undergoing free flap breast reconstruction does not appear warranted. There is no difference in major surgical complications such as flap loss with increasing age. However, older age does predispose patients to specific wound complications such as hematoma, skin necrosis, and delayed wound healing, which should guide preoperative counseling. Further, medical complications do not increase with advanced age. Overall, however, the safety of ABR in older patients appears uncompromised., Competing Interests: The views expressed are those of the authors and do not reflect the official policy or position of the US Army, Department of Defense or the US Government., (Thieme. All rights reserved.)
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- 2024
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22. Obesity as a Risk Factor in Cosmetic Abdominal Body Contouring: A Systematic Review and Meta-Analysis.
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Niu EF, Honig SE, Wang KE, Amro C, Davis HD, Habarth-Morales TE, Broach RB, and Fischer JP
- Subjects
- Humans, Risk Factors, Risk Assessment, Female, Abdominoplasty adverse effects, Abdominoplasty methods, Body Contouring adverse effects, Body Contouring methods, Obesity complications, Postoperative Complications epidemiology, Postoperative Complications etiology
- Abstract
Background: The incidence of obesity is on the rise around the globe. Outside of the massive weight loss (MWL) patient population, knowledge of risk factors associated with abdominal body contouring (BC) is limited. This systematic review and meta-analysis assesses the impact of obesity has on cosmetic abdominal BC outcomes., Methods: A systematic review conducted in accordance with PRISMA 2020 was done. PubMed, Embase, Scopus, and COCHRANE databases were reviewed under search syntax "obesity," "abdominoplasty," "panniculectomy," and "body contouring" for articles. Cosmetic was defined as abdominoplasty or panniculectomy outside the context of MWL. Obesity was defined as BMI ≥ 30 kg/m
2 . Studies reporting postoperative outcomes with less than 50% of their population involving MWL patients were included. Postoperative outcomes were assessed by pooled analysis and meta-analysis., Results: Of 3088 initial studies, 16 met inclusion criteria, and nine were used for pooled and meta-analysis. Meta-analysis demonstrated that obesity was associated with more seromas (OR 1.45, 1.06-1.98, p = 0.02), hematomas (OR 2.21, 1.07-4.57, p = 0.03), and total surgical site occurrences (OR 1.99, 1.30-3.04, p = 0.0016). There was no significant difference in odds of any other complications. Analysis by obesity class showed no significant increase in odds in seromas or wound dehiscence., Conclusions: This review demonstrates obesity increased odds of postoperative complications following cosmetic abdominal BC. However, risk of complications does not continue to increase with higher obesity class. A BMI ≥ 30 kg/m2 should not be a strict contraindication to cosmetic abdominal BC. Instead, plastic surgeons should evaluate patients on a case-by-case basis., Level of Evidence Iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 ., (© 2023. Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery.)- Published
- 2024
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23. Outcomes and Quality of Life After Resorbable Synthetic Ventral Hernia Repair in Contaminated Fields.
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Lemdani MS, Niu EF, Amro C, Gala Z, Ewing JN, Honig SE, Broach RB, and Fischer JP
- Subjects
- Humans, Middle Aged, Quality of Life, Herniorrhaphy adverse effects, Treatment Outcome, Surgical Wound Infection etiology, Surgical Mesh adverse effects, Recurrence, Retrospective Studies, Hernia, Ventral surgery, Incisional Hernia surgery
- Abstract
Introduction: The ideal mesh type for hernia repair in a contaminated field remains controversial. Data regarding outcomes beyond 1 year and the impact on quality of life (QoL) are unknown. This study aims to evaluate the long-term surgical outcomes and patient-reported outcomes (PROs) after contaminated repair with poly-4-hydroxybutyrate (P4HB) mesh., Materials Methods: Patients undergoing a contaminated hernia repair with P4HB between 2015 and 2020 were identified. Surgical site occurrences and hernia recurrences were recorded. Long-term PROs as defined by the Abdominal Hernia-Q and Hernia-Related Quality-of-Life Survey were assessed., Results: Fifty-five patients were included with a mean age of 54.5 years, a body mass index of 34 kg/m2, and a defect size of 356.9 ± 227.7 cm2. Median follow-up time was 49 months with a reoperation rate of 14.5% and a hernia recurrence rate of 7.3%. Of the 55 patients, 37 completed preoperative and postoperative PRO questionnaires. When comparing preoperative with postoperative Abdominal Hernia-Q, there was significant improvement in overall PROs (2.1 vs 3.5, P < 0.001). This improvement was maintained with no significant changes between postoperative scores over the course of 5 years. Patients with complications saw the same improvement in postoperative PRO scores as those without complications., Conclusions: Our study found a low hernia recurrence and acceptable long-term reoperation rates in patients undergoing hernia repair with P4HB mesh in a contaminated setting. We demonstrate a sustained significant improvement in QoL scores after hernia repair. These data yield insight into the long-term outcomes and QoL improvement, providing physicians further knowledge to better counsel their patients., Competing Interests: Conflicts of interest and sources of funding: Dr Fischer has received consulting payments from 3M; AbbVie; Baxter; Becton, Dickinson and Co; WL Gore; and Integra Life Sciences. He has received research support from the National Institutes of Health. No support was provided for this work., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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24. Comparative Analysis of Ventral Hernia Repair and Transverse Abdominis Release With and Without Panniculectomy: A 4-Year Match-Pair Analysis.
- Author
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Amro C, Ryan IA, Elhage SA, Messa CA 4th, Niu EF, McGraw JR, Broach RB, and Fischer JP
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- Humans, Quality of Life, Postoperative Complications surgery, Postoperative Complications etiology, Retrospective Studies, Herniorrhaphy methods, Surgical Mesh adverse effects, Recurrence, Hernia, Ventral surgery, Abdominoplasty methods, Lipectomy methods
- Abstract
Introduction: Amid rising obesity, concurrent ventral hernia repair and panniculectomy procedures are increasing. Long-term outcomes of transverse abdominis release (TAR) combined with panniculectomy remain understudied. This study compares clinical outcomes and quality of life (QoL) after TAR, with or without panniculectomy., Methods: A single-center retrospective review from 2016 to 2022 evaluated patients undergoing TAR with and without panniculectomy. Propensity-scored matching was based on age, body mass index, ASA, and ventral hernia working group. Patients with parastomal hernias were excluded. Patient/operative characteristics, postoperative outcomes, and QoL were analyzed., Results: Fifty subjects were identified (25 per group) with a median follow-up of 48.8 months (interquartile range, 43-69.7 months). The median age and body mass index were 57 years (47-64 years) and 31.8 kg/m2 (28-36 kg/m2), respectively. The average hernia defect size was 354.5 cm2 ± 188.5 cm2. There were no significant differences in hernia recurrence, emergency visits, readmissions, or reoperations between groups. However, ventral hernia repair with TAR and panniculectomy demonstrated a significant increase in delayed healing (44% vs 4%, P < 0.05) and seromas (24% vs 4%, P < 0.05). Postoperative QoL improved significantly in both groups (P < 0.005) across multiple domains, which continued throughout the 4-year follow-up period. There were no significant differences in QoL among ventral hernia working group, wound class, surgical site occurrences, or surgical site occurrences requiring intervention (P > 0.05). Patients with concurrent panniculectomy demonstrated a significantly greater percentage change in overall scores and appearance scores., Conclusions: Ventral hernia repair with TAR and panniculectomy can be performed safely with low recurrence and complication rates at long-term follow-up. Despite increased short-term postoperative complications, patients have a significantly greater improvement in disease specific QoL., Competing Interests: Conflicts of interest and sources of funding: Dr Fischer has received consulting payments from 3M, AbbVie, Baxter, Becton-Dickson, WL Gore, and Integra Life Sciences. He has received research funding support from the National Institutes of Health. The other authors have no disclosures., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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25. Discussion: Relationship between Body Mass Index and Outcomes in Microvascular Abdominally Based Autologous Breast Reconstruction.
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Niu EF, Amro C, and Fischer JP
- Subjects
- Humans, Female, Body Mass Index, Retrospective Studies, Postoperative Complications, Mammaplasty, Breast Neoplasms surgery
- Published
- 2024
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26. Non-Small Cell Lung Cancer Causing Atraumatic Splenic Rupture Without Splenic Metastasis.
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Amro C, Pepe RJ, Parekh AT, and Butts CA
- Subjects
- Humans, Female, Middle Aged, Splenectomy adverse effects, Carcinoma, Non-Small-Cell Lung complications, Splenic Neoplasms complications, Splenic Neoplasms surgery, Lung Neoplasms complications, Splenic Rupture etiology, Splenic Rupture surgery
- Abstract
Atraumatic splenic rupture (ASR) is a rare occurrence but an important clinical entity. Although trauma is the most common cause of splenic rupture, there is limited literature on ASR. This case report discusses a 59-year-old woman presenting with tension hydrothorax and ASR in the setting of non-small cell lung carcinoma requiring emergent chest tube insertion and emergent splenectomy. Her hospital course was complicated by pulmonary embolism and thrombosis of the inferior vena cava. The patient expired three months after her initial presentation. This patient's presentation represents only the second documented case of atraumatic splenic rupture secondary to metastatic lung carcinoma without pathological evidence of splenic metastasis. Atraumatic splenic rupture secondary to metastatic NSCLC is a rare occurrence; though failure to detect, it may be fatal. Pathologic ASR may be an occult presentation of lung malignancy and in the presence of confirmed NSCLC may portend a poor prognosis.
- Published
- 2023
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27. Traumatic Popliteal Artery Occlusion Following Lower Extremity Crush Injury Presenting With Isolated Patellar Dislocation.
- Author
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Amro C, Parekh AT, Diamond K, Lissauer ME, and Butts CA
- Subjects
- Male, Humans, Aged, Popliteal Artery surgery, Popliteal Artery injuries, Lower Extremity, Retrospective Studies, Treatment Outcome, Patellar Dislocation complications, Leg Injuries complications, Vascular System Injuries complications, Vascular System Injuries diagnosis, Crush Injuries complications
- Abstract
While traumatic popliteal artery injury historically has a low incidence, failure to acutely recognize the vascular insult poses a significant risk of limb loss and functional impairment. A 71-year-old male presented with left lower extremity pain in setting of a crush injury working underneath a vehicle resulting in an isolated lateral dislocation of his patella and complete occlusion of the distal popliteal artery. He was taken to the operating room for an in-situ bypass and four-compartment fasciotomy. His hospital stay included three staged washouts/debridements with eventual closure. He was discharged after 38 days to a rehabilitation facility with ability to self-ambulate with assistance within one month. This patient's presentation is unique for his isolated patellar dislocation without associated injuries characteristically associated with a traumatic vascular injury of the popliteal artery and serves to remind the importance of complete examination in the setting of blunt trauma.
- Published
- 2023
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28. Utility of computed tomography reconstructed thoracolumbar spinal imaging in blunt trauma.
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Swarup A, Amro C, Choron RL, Cong A, Park J, Butts CA, Goswami J, and Teichman AL
- Subjects
- Humans, Retrospective Studies, Quality of Life, Thoracic Vertebrae diagnostic imaging, Thoracic Vertebrae injuries, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae injuries, Tomography, X-Ray Computed methods, Magnetic Resonance Imaging, Wounds, Nonpenetrating diagnostic imaging, Fractures, Bone, Spinal Fractures diagnostic imaging
- Abstract
Objectives: Fractures of the thoracolumbar (TL) spine are common and may cause neurologic damage, pain, and reduced quality of life. Computed tomography (CT) TL reconstructions from CT chest, abdomen, and pelvis (CAP) are used to identify TL fractures; however, their benefit over CAP imaging is unclear. We hypothesized that reformatted TL images do not identify additional clinically significant injuries or change outcomes., Methods: Retrospective data were collected 2016 to 2021 from trauma patients at a level 1 trauma center. All patients 18 years or older with TL fractures on CT CAP with/without CT TL reformats were included. Clinically significant TL fractures were defined as requiring operative fixation, brace, or spinal rehabilitation. A binary classification model was created to assess the diagnostic utility of CTCAP compared with CTTL in predicting clinically significant fractures in patients who underwent CT CAP/TL., Results: There were 828 patients with TL fractures, 634 had both CT CAP/CT TL (CAPTL) and 194 CTCAP only (CAP). There were 134 clinically significant TL fractures (16%) (14 [7.2%] CT CAP vs. 120 [18.9%] CT CAPTL, p < 0.001). There were no differences among unstable fractures, fractures on magnetic resonance imaging (MRI) only, mortality, or neurologic deficits on discharge between CAPTL and CAP ( p > 0.05). Among clinically significant fractures, CAPTL was not associated with increased MRI utilization, surgery, spinal brace, or spinal cord rehabilitation ( p > 0.05). Among clinically insignificant fractures, CAPTL was associated with increased MRIs, length of stay (LOS), and intensive care unit LOS ( p < 0.05). CAPTL was also an independent predictor of increased MRIs (odds ratio, 5.79; 95% confidence interval, 2.29-14.65; p < 0.01) and spine consultation (odds ratio, 2.39; 95% confidence interval, 1.64-3.67; p < 0.01). More CT CAP/TL were performed in those with clinically significant fractures; however, CTCAP was equivalent to CTTL for detection of fractures ( p > 0.05)., Conclusion: CTCAP alone is sufficient to identify clinically significant TL fractures. While the addition of TL reformatted imaging minimizes missed injuries, it is associated with increased hospital LOS and MRI resource utilization. Therefore, careful consideration is needed for appropriate CT TL patient selection., Level of Evidence: Therapeutic/Care Management; Level IV., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2023
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29. Preoperative Botulinum Toxin for Abdominal Wall Reconstruction in Massive Hernia Defects-A Propensity-Matched Analysis.
- Author
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Niu EF, Kozak GM, McAuliffe PB, Amro C, Bascone C, Honig SE, Elsamaloty LH, Hao M, Broach RB, Kovach SJ 3rd, and Fischer JP
- Subjects
- Adult, Humans, Male, Middle Aged, Retrospective Studies, Herniorrhaphy methods, Surgical Mesh, Recurrence, Abdominal Wall surgery, Botulinum Toxins, Hernia, Ventral surgery, Incisional Hernia surgery
- Abstract
Purpose: Reconstruction of massive incisional hernias (IHs) poses a significant challenge with high rates of recurrence. Preoperative chemodenervation using botulinum toxin (BTX) injections in the abdominal wall is a technique that has been used to facilitate primary fascial closure. However, there is limited data directly comparing primary fascial closure rates and postoperative outcomes after hernia repair between patients who do and do not receive preoperative BTX injections. The objective of our study was to compare the outcomes of patients who did and did not receive BTX injections before abdominal wall reconstruction., Methods: This is a retrospective cohort study including adult patients from 2019 to 2021 who underwent IH repair with and without preoperative BTX injections. Propensity score matching was performed based on body mass index, age, and intraoperative defect size. Demographic and clinical data were recorded and compared. The statistical significance level was set at P < 0.05., Results: Twenty patients underwent IH repair with preoperative BTX injections. Twenty patients who underwent IH repair without preoperative BTX injections were selected to comprise a 1:1 propensity-matched control cohort. The average defect size was 663.9 cm2 in the BTX group and 640.7 cm2 in the non-BTX group (P = 0.816). There was no difference in average age (58.6 vs 59.2 years, P = 0.911) and body mass index (33.0 vs 33.2 kg/m2, P = 0.911). However, there was a greater proportion of male patients in the BTX group (85% vs 55%, P = 0.082).Primary fascial closure was achieved in 95% of BTX patients and 90% of non-BTX patients (P = 1.0). Significantly fewer patients in the BTX group required component separation techniques to achieve primary fascial closure (65% vs 95%, P = 0.044). There was no significant difference in any postoperative surgical and medical outcomes. Hernia recurrence was 10% in the BTX group and 20% in non-BTX group (P = 0.661)., Conclusions: In our study, we observed a lower rate of component separations to achieve primary fascial closure among patients with massive hernia defects who received preoperative BTX injections. These results suggest that preoperative BTX injections may "downstage" the complexity of hernia repair with abdominal wall reconstruction in patients with massive hernia defects and reduce the need for component separation., Competing Interests: Conflicts of interest and sources of funding: none declared., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2023
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30. The Role of Dedicated Research Training in Promoting Academic Success in Plastic Surgery: Analysis of 949 Faculty Career Outcomes.
- Author
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McGraw JR, Amro C, Niu EF, Honig SE, Broach RB, Fischer JP, Kovach SJ 3rd, and Azoury SC
- Abstract
This study aimed to analyze the association between completion of research training and career success in American plastic surgery faculty to aid trainees in their decisions to perform research fellowships., Methods: A cross-sectional analysis of attending academic plastic surgeons in the United States was conducted. Outcomes were compared between faculty who completed research training (research fellowship, PhD, or MPH) and those who did not. Outcomes included promotion to full professor and/or department chair, h-index, and attainment of National Institutes of Health funding. Outcomes were analyzed using chi-squared tests, t tests, and multivariable regressions., Results: A total of 949 plastic surgery faculty members were included, and of those, 185 (19.5%) completed dedicated research training, including 13.7% (n = 130) who completed a research fellowship. Surgeons who completed dedicated research training were significantly more likely to achieve full professorship (31.4% versus 24.1%, P = 0.01), obtain National Institutes of Health funding (18.4% versus 6.5%, P < 0.001), and have a higher mean h-index (15.6 versus 11.6, P < 0.001). Dedicated research fellowships were independently predictive of achieving full professorship (OR = 2.12, P = 0.002), increased h-index (β = 4.86, P < 0.001), and attainment of National Institutes of Health funding (OR = 5.06, P = 0.01). Completion of dedicated research training did not predict an increased likelihood of becoming department chair., Conclusion: The performance of dedicated research training was predictive of improved markers of career success in plastic surgery and should be considered beneficial in both the short and long term., Competing Interests: The authors have no financial interest to declare in relation to the content of this article., (Copyright © 2023 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.)
- Published
- 2023
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31. Large Gathering Attendance is Associated with Increased Odds of Contracting COVID-19: A Survey Based Study.
- Author
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Schroeder ME, Manderski MT, Amro C, Swaminathan S, Parekh A, Yoshitake S, Yang J, Romeo P, Reyes D, Choron R, and Rodricks M
- Subjects
- COVID-19 Testing, Humans, Pandemics, SARS-CoV-2, Surveys and Questionnaires, COVID-19 epidemiology
- Abstract
We used a telephone survey to determine risk factors associated with a positive polymerase chain reaction test of a nasopharyngeal swab for severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) at a community hospital in Central New Jersey during the early stages of the pandemic. We compared survey responses of 176 patients in March 2020. Respondents were asked about their living situation, work environment, use of public transportation and attendance at one or more large gatherings (more than 10 people) in the 3 weeks prior to undergoing COVID testing. We found that those who attended a large gathering in the 3 weeks prior to their COVID test had a 2.50 odds ratio (95% CI 1.19, 5.22) of testing positive after controlling for age, sex, race/ethnicity, occupation, living situation and recent visit to a nursing home. The total number of gatherings attended or the number of people in attendance was not associated with a positive test. An association was also seen for specific job types such as factory workers, construction workers, and facilities managers. Attendance at a gathering of more than ten people was associated with testing positive for COVID-19., (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2022
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32. The Utility of Lower Extremity Screening Duplex for the Detection of Deep Vein Thrombosis in Trauma.
- Author
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Teichman AL, Walls D, Choron RL, Butts CA, Krumrei N, Amro C, Swaminathan S, Arcomano N, Parekh A, and Romeo P
- Subjects
- Humans, Lower Extremity blood supply, Lower Extremity diagnostic imaging, Male, Retrospective Studies, Risk Factors, Trauma Centers, Ultrasonography, Doppler, Duplex, Venous Thromboembolism diagnostic imaging, Venous Thromboembolism epidemiology, Venous Thrombosis diagnostic imaging, Venous Thrombosis etiology, Wounds and Injuries complications
- Abstract
Background: Trauma patients are high-risk for venous thromboembolism (VTE). Lower extremity screening duplex ultrasonography (LESDUS) is controversial and not standardized for early VTE diagnosis. By implementing risk stratification and selective screening, we aim to optimize resource utilization., Materials and Methods: A retrospective review were conducted at a Level-1 Trauma Center, January 2015-October 2019. LESDUS was performed within 72-h of presentation, then weekly. Demographics, VTE data, and outcomes were collected from the trauma registry. Risk assessment profile (RAP) score was calculated based on collected data., Results: Of 5,645 patients included, 2,813 (49.8%) were screened for lower extremity deep vein thrombosis (LEDVT). Of 187 patients with LEDVT, 154 were diagnosed on LESDUS, 18 after negative LESDUS, and 15 in unscreened patients. Patients with VTE were older (61y versus 55, P < 0.01), more often male (70.9% versus 29.1%, P = 0.03), had higher ISS (16 versus 10, P < 0.01), longer hospital length of stay (LOS) (11.5 d versus 3, P < 0.01), longer ICU LOS (4.5 d versus 1, P < 0.01), and increased mortality (9.1% versus 4.3%, P = 0.01). RAP was higher in VTE patients versus those without (nine versus three, P < 0.01). RAP ≥8 was 62.5% sensitive and 70.4% specific for VTE. Chemoprophylaxis delay also correlated with increased VTE (OR = 1.48, 95% CI = 1.03-2.12)., Conclusions: VTE remains a significant complication in trauma patients. Despite a universal LESDUS protocol, only 50% of patients underwent screening and 20% of all LE DVTs were not identified on LESDUS. To optimize resource utilization and protocol adherence, LESDUS should only be performed if RAP ≥8 or if unable to administer timely chemoprophylaxis., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2022
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33. Amyand's hernia complicated with appendicitis: an interval approach with transabdominal laparoscopic appendectomy and laparoscopic hernioplasty-a case report.
- Author
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Parekh AT, Diamond K, Littlejohn M, Ehsani-Nia H, and Amro C
- Abstract
Amyand's hernia is a rare classification of inguinal hernia where the vermiform appendix is located within the hernial sac. This case report discusses a patient presenting with abdominal and groin pain shown to be an Amyand's hernia complicated by acute appendicitis on computed tomography. The patient was treated with a two-stage approach, involving transabdominal laparoscopic appendectomy and elective laparoscopic hernioplasty after recovery. As some controversy exists regarding the timing of appendectomy and hernioplasty, we examine the benefits of the interval approach in the reduction of postoperative infection risk compared with a concurrent approach in patients presenting with Amyand's hernia complicated by appendiceal inflammation., (Published by Oxford University Press and JSCR Publishing Ltd 2021.)
- Published
- 2021
- Full Text
- View/download PDF
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