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Objective: Innovative therapies such as thermoembolization are expected to play an important role in improvising care for patients with diseases such as hepatocellular carcinoma. Thermoembolization is a minimally invasive strategy that combines thermal ablation and embolization in a single procedure. This approach exploits an exothermic chemical reaction that occurs when an acid chloride is delivered via an endovascular route. However, comprehension of the complexities of the biophysics of thermoembolization is challenging. Mathematical models can aid in understanding such complex processes and assisting clinicians in making informed decisions. In this study, we used a Hagen Poiseuille 1D blood flow model to predict the mass transport and possible embolization locations in a porcine hepatic artery. Method: The 1D flow model was used on in vivo embolization imaging data of three pigs. The hydrolysis time constant of acid chloride chemical reaction was optimized for each pig, and LOOCV method was used to test the model's predictive ability. Conclusion: This basic model provided a balanced accuracy rate of 66.8% for identifying the possible locations of embolization in the hepatic artery. Use of the model provides an initial understanding of the vascular transport phenomena that are predicted to occur as a result of thermoembolization.

We revise the cosmological interaction between dark energy and dark matter. More precisely, we focus on models that support compartmentalization or co-existence in the dark sector of the universe. Within the framework of a homogeneous and isotropic, spatially flat Friedmann--Lema\^itre--Robertson--Walker geometry, we analyse the asymptotic behaviour of the physical parameters for two interacting models, where dark energy and dark matter have constant equations of state parameters, in the presence of dark radiation, when dark energy is described by a quintessence scalar field. For each model, we determine the asymptotic solutions and attempt to understand how the interaction affects the cosmological evolution and history., Comment: 40 pages, 17 figures; version to appear in Physics of the Dark Universe

This paper investigates the impact of the effects of bulk viscosity on the accelerating expansion and large-scale structure formation of a universe in which the underlying gravitational interaction is described by $f(Q)$ gravity. Various toy models of the $f(Q)$ gravity theory, including power-law ($f_{1\rm{CDM}}$), exponential ($f_{2\rm{CDM}}$), and logarithmic ($f_{3\rm{CDM}}$) are considered. To test the cosmological viability of these models, we use 57 Hubble parameter data points (OHD), 1048 supernovae distance modulus (SNIa), their combined analysis (OHD+SNIa), 14 growth rate ($f$-data), and 30 redshift-space distortions ($f\sigma_8$) datasets. We compute the best-fit values $\Omega_m, H_0$ and exponents $\{n, p, \gamma\}$ including the bulk viscosity coefficient $\zeta_0$, through a detailed statistical analysis. Moreover, we study linear cosmological perturbations and compute the density contrast \(\delta(z)\), growth factor $D(z)$, growth rate $(f(z)$, and redshift-space distortion $f\sigma_8(z)$. Based on the Akaike Information Criterion (AIC) and Bayesian / Schwartz Information Criterion (BIC), a statistical comparison of the $f(Q)$ gravity models with \lcdm is made. From our statistical analysis of cosmic measurements, we found an underestimation of all models on the OHD data; therefore, statistical viability led us to weigh it in favour of SNIa data which resulted in the exponential ($f_{2\rm{CDM}}$) model without bulk viscosity being the most plausible alternative model, while on average the $f_{1\rm{CDM}}$ model performed statistically the weakest. We also found that adding bulk viscosity did not improve the fit of the models to all observational data., Comment: 16 pages, 9 Tables, 8 Figures

This paper investigates the integration and validation of multi-energy systems within the H2020 ERIGrid 2.0 project, focusing on the deployment of the JaNDER software middleware and universal API (uAPI) to establish a robust, high-data-rate, and low-latency communication link between Research Infrastructures (RIs). The middleware facilitates seamless integration of RIs through specifically designed transport layers, while the uAPI provides a simplified and standardized interface to ease deployment. A motivating case study explores the provision of power-to-heat services in a local multi-energy district, involving laboratories in Denmark, Greece, Italy, the Netherlands, and Norway, and analyzing their impact on electrical and thermal networks. This paper not only demonstrates the practical application of Geographically Distributed Simulations and Hardware-in-the-Loop technologies but also highlights their effectiveness in enhancing system flexibility and managing grid dynamics under various operational scenarios., Comment: 6 pages, 10 figures, Accepted for presentation to the 2024 Open Source Modelling and Simulation of Energy Systems (OSMSES 2024), Vienna, Austria

This paper delves into the late-time accelerated expansion of the universe and the evolution of cosmic structures within the context of a specific \( f(R, L_m) \) gravity model, formulated as \( f(R, L_m) = \lambda R + \beta L_m^\alpha + \eta \). To study the cosmological viability of the model, we employed the latest cosmic measurement datasets: i) 57 observational Hubble parameter data points (\texttt{OHD}); ii) 1048 distance moduli data points (\texttt{SNIa}); iii) a combined dataset (\texttt{OHD+SNIa}); and large scale structure datasets, including iv) 14 growth rate data points (\texttt{f}); and v) 30 redshift space distortion data points (\texttt{f}$\sigma_8$). These datasets facilitated the constraint of the \( f(R, L_m) \)-gravity model via MCMC simulations, followed by a comparative analysis with the \(\Lambda\)CDM model. A comprehensive statistical analysis has been conducted to evaluate the \( f(R, L_m) \)-gravity model's efficacy in explaining both the accelerated expansion of the universe and the growth of cosmic structures., Comment: 12 pages, 11 figures, 5 tables

We take into account redshift-space distortion measurements to investigate the growth of cosmological large-scale structures within the framework of modified symmetric teleparallel $f(Q)$ gravity. After comparing the predictions of the $f(Q)$-gravity expansion history with OHD and SNIa datasets and constraining the pertinent cosmological parameters $\Omega_{m}$ and $H_0$, together with the exponent $n$ for $f(Q)$ power-law models, we derive the full system of equations governing linear cosmological perturbations to study matter fluctuations using the $1 + 3$ covariant formalism when applied to $f(Q)$ gravity. Thus, we resort to both the usual redshift-space distortion data $f\sigma_8$ and some recent separate measurements of the growth rate $f$ and the amplitude of matter fluctuations $\sigma_8$ from the VIPERS and SDSS collaborations to find the best-fit cosmological parameters $\Omega_m$, $\sigma_{8}$ and $n$. We also apply a collective analysis of such growth-structure data together with the aforementioned cosmic expansion measurements, to restrict these parameters through Monte Carlo Markov Chain simulations. determining the statistical significance for the best-fit parameter values through the AIC and BIC Bayesian selection criteria., Comment: 7 Figures, 6 Tables, 22 pages

Weakly interacting massive particles (WIMPs) are well-motivated candidates for dark matter. One signature of galactic WIMPs is the annual modulation expected in a detector's interaction rate, which arises from Earth's revolution around the Sun. Over two decades, the DAMA/LIBRA experiment has observed such modulation with 250 kg of NaI(Tl) scintillators, in accordance with WIMP expectations but inconsistent with the negative results of other experiments. The signal depends on the target material, so to validate or refute the DAMA result, the experiment must be replicated using the same material. This is the goal of the ANAIS-112 experiment, currently underway since August 2017 with 112.5 kg of NaI(Tl). In this work, we present a reanalysis of three years of data employing an improved analysis chain to enhance the experimental sensitivity. The results presented here are consistent with the absence of modulation and inconsistent with DAMA's observation at nearly 3$\sigma$ confidence level, with the potential to reach a 5$\sigma$ level within 8 years from the beginning of the data collection. Additionally, we explore the impact of different scintillation quenching factors in the comparison between ANAIS-112 and DAMA/LIBRA., Comment: 16 pages, 10 figures, 1 table

We present a dynamical system formulation for inhomogeneous LRS-II spacetimes using the covariant 1+1+2 decomposition approach. Our approach describes the LRS-II dynamics from the point of view of a comoving observer. Promoting the covariant radial derivatives of the covariant dynamical quantities to new dynamical variables and utilizing the commutation relation between the covariant temporal and radial derivatives, we were able to construct an autonomous system of first-order ordinary differential equations along with some purely algebraic constraints. Using our dynamical system formulation we found several interesting features in the LRS-II phase space with dust, one of them being that the homogeneous solutions constitute an invariant submanifold. For the particular case of LTB, we were also able to recover the previously known result that an expanding LTB tends to Milne in the absence of a cosmological constant, providing a potential validation of our formalism., Comment: JCAP accepted version. Acknowledgement modified

ANAIS is a direct dark matter detection experiment whose goal is to confirm or refute in a model independent way the positive annual modulation signal claimed by DAMA/LIBRA. Consisting of 112.5 kg of NaI(Tl) scintillators, ANAIS-112 is taking data at the Canfranc Underground Laboratory in Spain since August, 2017. Results corresponding to the analysis of three years of data are compatible with the absence of modulation and incompatible with DAMA/LIBRA. However, testing this signal relies on the knowledge of the scintillation quenching factors (QF), which measure the relative efficiency for the conversion into light of the nuclear recoil energy with respect to the same energy deposited by electrons. Previous measurements of the QF in NaI(Tl) show a large dispersion. Consequently, in order to better understand the response of the ANAIS-112 detectors to nuclear recoils, a specific neutron calibration program has been developed. This program combines two different approaches: on the one hand, QF measurements were carried out in a monoenergetic neutron beam; on the other hand, the study presented here aims at the evaluation of the QF by exposing directly the ANAIS-112 crystals to neutrons from low activity $^{252}$Cf sources, placed outside the lead shielding. Comparison between these onsite neutron measurements and detailed GEANT4 simulations will be presented, confirming that this approach allows testing different QF models., Comment: Contributed to the TAUP2023 Conference, August-September 2023. To be published in Proceeding of Science

In this paper, we investigate the evolution of cosmological perturbations within the context of Bianchi Type$-I$ spacetimes. We consider models containing viscous fluids with evolving cosmological (\LL) and Newtonian gravitational (G) parameters. The investigation of how over-densities in the viscous matter content in the Bianchi Type$-I$ model is our primary emphasis. In particular, we investigate the generation and propagation of signals associated with large-scale structures in this setting. We contrast our findings with the predictions of the classic $\Lambda$CDM ($\Lambda$-Cold-Dark-Matter) cosmological model to draw relevant contrasts and insights. Our findings emphasise the need to incorporate viscous fluids into the Bianchi Type$-I$ geometry, as well as the dynamic fluctuations of \LL and $G$. These factors influence the rate of structure growth in the cosmos as a whole. Thus, our findings offer light on the complex dynamic interaction between viscosity, changing cosmological parameters, and the growth of large-scale structures in an anisotropic universe., Comment: 12 pages, 6figures

The ANAIS experiment is intended to search for dark matter annual modulation with ultrapure NaI(Tl) scintillators in order to provide a model independent confirmation or refutation of the long-standing DAMA/LIBRA positive annual modulation signal in the low energy detection rate, using the same target and technique. Other experiments exclude the region of parameters singled out by DAMA/LIBRA. However, these experiments use different target materials, so the comparison of their results depends on the models assumed for the dark matter particle and its distribution in the galactic halo. ANAIS-112, consisting of nine 12.5 kg NaI(Tl) modules produced by Alpha Spectra Inc., disposed in a 3$\times$3 matrix configuration, is taking data smoothly with excellent performance at the Canfranc Underground Laboratory, Spain, since August, 2017. Last published results corresponding to three-year exposure were compatible with the absence of modulation and incompatible with DAMA/LIBRA for a sensitivity above 2.5$\sigma$ C.L. Present status of the experiment and a reanalysis of the first 3 years data using new filtering protocols based on machine-learning techniques are reported. This reanalysis allows to improve the sensitivity previously achieved for the DAMA/LIBRA signal. Updated sensitivity prospects are also presented: with the improved filtering, testing the DAMA/LIBRA signal at 5$\sigma$ will be within reach in 2025., Comment: Contributed to the TAUP2023 Conference, August-September 2023. To be published in Proceeding of Science. arXiv admin note: substantial text overlap with arXiv:2110.10649, arXiv:2209.14113

We present a joint cosmological analysis of the power spectra measurement of the Planck Compton parameter and the integrated Sachs-Wolfe (ISW) maps. We detect the statistical correlation between the Planck Thermal Sunyaev-Zeldovich (tSZ) map and ISW data with a significance of a $3.6\sigma$ confidence level~(CL), with the autocorrelation of the Planck tSZ data being measured at a $25 \sigma$ CL. The joint auto- and cross-power spectra constrain the matter density to be $\Omega_{\rm m}= 0.317^{+0.040}_{-0.031}$, the Hubble constant $H_{0}=66.5^{+2.0}_{-1.9}\,{\rm km}\,{\rm s}^{-1}\,{\rm Mpc}^{-1}$ and the rms matter density fluctuations to be $\sigma_{8}=0.730^{+0.040}_{-0.037}$ at the 68% CL. The derived large-scale structure $S_{8}$ parameter is $S_8 \equiv \sigma_{8}(\Omega_{\rm m}/0.3)^{0.5} = 0.755\pm{0.060} $. If using only the diagonal blocks of covariance matrices, the Hubble constant becomes $H_{0}=69.7^{+2.0}_{-1.5}\,{\rm km}\,{\rm s}^{-1}\,{\rm Mpc}^{-1}$. In addition, we obtain the constraint of the product of the gas bias, gas temperature, and density as $b_{\rm gas} \left(T_{\rm e}/(0.1\,{\rm keV}) \right ) \left(\bar{n}_{\rm e}/1\,{\rm m}^{-3} \right) = 3.09^{+0.320}_{-0.380}$. We find that this constraint leads to an estimate on the electron temperature today as $T_{\rm e}=(2.40^{+0.250}_{-0.300}) \times 10^{6} \,{\rm K}$, consistent with the expected temperature of the warm-hot intergalactic medium. Our studies show that the ISW-tSZ cross-correlation is capable of probing the properties of the large-scale diffuse gas., Comment: 25 pages, 15 figures, 2 tables

Despite the significant accomplishments of general relativity, numerous unresolved issues persist in our understanding of the cosmos. One of the most perplexing challenges is the ongoing accelerated expansion of the Universe, which continues to elude a complete explanation. Consequently, scientists have proposed various alternative theories to GR in pursuit of a deeper understanding. In our analysis, we delve into the recently proposed modified $f(Q)$ gravity, where $Q$ represents the non-metricity scalar responsible for gravitational effects. Specifically, we investigate a cosmological model characterized by the functional form $f(Q) = Q+\alpha Q^n$, where $\alpha$ (with $\alpha \neq 0$) and $n$ serve as free parameters. Utilizing this functional form, we construct our Hubble rate, incorporating a specific equation of state to describe the cosmic fluid. Furthermore, we leverage a dataset consisting of 31 data points from Hubble measurements and an additional 1048 data points from the Pantheon dataset. These data serve as crucial constraints for our model parameters, and we employ the Markov Chain Monte Carlo (MCMC) method to explore the parameter space and derive meaningful results. With our parameter values constrained, our analysis yields several noteworthy findings. The deceleration parameter suggests a recent accelerated phase in the cosmic expansion. In addition, the EoS parameter paints a portrait of dark energy exhibiting phantom-like characteristics. Furthermore, we delve into the application of cosmological diagnostic tools, specifically the statefinder and the $Om(z)$ diagnostics. Both of these tools align with our previous conclusions, confirming the phantom-like behavior exhibited by our cosmological model. These results collectively contribute to our understanding of the dynamic interplay between gravity, dark energy, and the expanding cosmos., Comment: Progress of Theoretical and Experimental Physics accepted version

Smart energy systems comprise multiple domains like power, thermal, control, information, and communication technology, which increases the complexity of research and development studies. This expansion also requires larger and ever so complex experimental pilot environments driving the demand for geographically distributed multi-research infrastructure tests. The Holistic Test Description approach supports the design of multi-domain and multi-research infrastructure tests by organizing the test cases into comprehensive segments, ensuring all relevant items for testing are covered. These test cases eventually form a pool, which to understand holistically would require studying and reading all the descriptions. This work proposes therefore the concept of Test Case Profiles to improve test case discovery and the structured creation of them. Test Case Profiles add further structure to the indexing in test case repositories. Along with the proposed indexing method, four different use cases are introduced to motivate additional applications of the proposed concept., Comment: 2023 Open Source Modelling and Simulation of Energy Systems (OSMSES)

We conduct a Bayesian analysis of recent observational datasets, specifically the Cosmic Chronometers (CC) dataset and Pantheon samples, to investigate the evolution of the EoS parameter in dark energy models. Our study focused on the effective EoS parameter, which is described by the parametric form $\omega_{eff}=-\frac{1}{1+m(1+z)^n}$, where $m$ and $n$ are model parameters. This parametric form is applicable within the framework of $f(R,L_m)$ gravity, where $R$ represents the Ricci scalar and $L_m$ is the matter Lagrangian. Here, we examine a non-linear $f(R,L_m)$ model characterized by the functional form $f(R,L_m)=\frac{R}{2}+L_m^\alpha$, where $\alpha$ is the free parameter of the model. We examine the evolution of several cosmological parameters, including the effective EoS parameter $\omega_{eff}$, the deceleration parameter $q$, the density parameter $\rho$, the pressure $p$, and the statefinder parameters. Our analysis revealed that the constrained current value of the effective EoS parameter, $\omega_{eff}^{0}=-0.68\pm0.06$ for both the CC and Pantheon datasets, points towards a quintessence phase. Moreover, at redshift $z=0$, the deceleration parameter, $q_0 = -0.61^{+0.01}_{-0.01}$, indicates that the present Universe is undergoing accelerated expansion., Comment: The European Physical Journal Plus published version