Search

Your search keyword '"Aman, Makbul"' showing total 12 results
Start Over Author "Aman, Makbul"
12 results on '"Aman, Makbul"'

6. Albumin excretion rate among patients with diabetic retinopathy

Author

Aman, Makbul, Rasyid, Haerani, Sartika, Suriana Dwi, Sanusi, Himawan, Kasim, Hasyim, Bakri, Syakib, Ichsan, Muhammad, and Seweng, Arifin

Subjects
albumin excretion rate, diabetes mellitus type 2, diabetic retinopathy, lcsh:Internal medicine, endocrine system diseases, Original Article, lcsh:RC31-1245
Abstract

Background: Chronic microvascular complications consist of diabetic nephropathy (DN), diabetic retinopathy (DR), and diabetic neuropathy. Diabetic nephropathy is assessed through albuminuria, and diabetic retinopathy is assessed through fundoscopy. Several studies have assessed the albuminuria in diabetic retinopathy but have found inconclusive results. This study aims to investigate the albumin excretion rate in patients with diabetic retinopathy. Methods: A cross sectional design was applied in this study. The diagnosis of type 2 diabetes mellitus was determined based on the anamnesis and laboratory examinations. The study was conducted at Dr. Wahidin Sudirohusodo Hospital and Hasanuddin University Hospital in Makassar during November 2018 until April 2019. The stages of diabetic retinopathy were based on funduscopic examinations. In addition, the blood pressure, BMI, albumin excretion rate, lipid profile, and HbA1C were also examined. Chi Square and Kappa tests were performed in the statistical analysis. Results: 120 subjects with type 2 diabetes mellitus were observed. Of the total subjects, the number of females within the age of 36-79 years made up the biggest fraction. There was a significant relation between hypertension comorbidity with the albumin excretion rate and grading diabetic retinopathy where the A3 and proliferative diabetic retinopathy (PDR) percentages were higher in the hypertension group at 68.8% and 54.5%. There was also a significant correlation between incidence of albuminuria with diabetic retinopathy. Particularly, proliferative diabetic retinopathy (PDR) remained associated with albuminuria, while non-proliferative diabetic retinopathy (NPDR) was related to non-albuminuria. Conclusion: Albuminuria incidence confirms association with diabetic retinopathy grading.

Published
2020

7. High uric acid level increases the risk of acute kidney injury in acute coronary syndrome patients.

Author

Puti, Erny, Rasyid, Haerani, Tandean, Pendrik, Sanusi, Himawan, Kasim, Hasyim, Bakri, Syakib, Aman, Makbul, and Seweng, Arifin

Subjects
CARDIOVASCULAR diseases, ACUTE kidney failure, URIC acid, KIDNEY function tests, CROSS-sectional method
Abstract

Background: Both clinical and experimental evidence have been published over the past few decades supporting the existence of a close relationship between the elevated levels of serum uric acid with cardiovascular events and acute kidney injury (AKI). This study aimed to determine the effect of serum uric acid levels on the incidence of AKI in acute coronary syndrome (ACS) patients. Methods: A retrospective cohort study with a cross sectional design was performed. The research was conducted at Dr. Wahidin Sudirohusodo Hospital from October 2019 to December 2019. Nonrandom sampling was employed in the medical records. All patients who met the inclusion criteria were at > 18 years old and diagnosed with ACS with AKI. The demographic data of age, sex and serum uric acid levels were recorded. The data obtained were analyzed using the SPSS (Statistical Package for Social Sciences). Results: There were 158 subjects of ACS patients with AKI and 135 without AKI. There was a significant correlation between high uric acid levels with the incidence of AKI in ACS (p<0.001). Patients with high serum uric acid levels were 9.5 times at risk of developing AKI compared to those with normal serum uric acid levels. Conclusion: High uric acid level is one of the risk factors for AKI in ACS and indicates 9.5 times at risk of developing AKI compared to normal serum uric acid level. Therefore, it is necessary to monitor serum uric acid level and kidney function in ACS patients. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

10. Effect of Hylocereus polyrhizus Extract to VEGF and TGF-β1 Level in Acute Wound Healing of Wistar Rats.

Author

Tahir, Takdir, Bakri, Syakib, Patellongi, Ilhamjaya, Aman, Makbul, Miskad, Upik A., Yunis, Maryunis, and Yusuf, Saldy

Subjects
LABORATORY rats, WOUND healing, OINTMENTS, GRANULATION tissue, EXTRACTS
Abstract

Copyright of Jordan Journal of Pharmaceutical Sciences is the property of University of Jordan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021

11. Evaluation of Topical Red Dragon Fruit Extract Effect (Hylocereus Polyrhizus) on Tissue Granulation and Epithelialization in Diabetes Mellitus (DM) and Non-DM Wistar Rats: Pre Eliminary Study

Author

Tahir, Takdir, Bakri, Syakib, Patellongi, Ilhamjaya, Aman, Makbul, A. Miskad, Upik, Maryunis, Maryunis, Yusuf, Saldy, Rahayu, Ade Irma, Syam, Ahmad Dahlan, Hasriyani, Hasriyani, Tahir, Takdir, Bakri, Syakib, Patellongi, Ilhamjaya, Aman, Makbul, A. Miskad, Upik, Maryunis, Maryunis, Yusuf, Saldy, Rahayu, Ade Irma, Syam, Ahmad Dahlan, and Hasriyani, Hasriyani

Abstract

The use of natural materials as wound healing is an alternative that is widely used. Red Dragon Fruit Extract (EBNM) has antioxidant and anti-inflammatory content that is needed to accelerate the wound healing, but studies have reported effects on wound healing is still limited. The purpose of this study was to evaluate the effect of topical Red Dragon Fruit Extract on DM wound and Non-DM wound healing in Wistar rats. This research method is an Experimental Study with post-test with control group design. Albino Male Wistar rat (n = 18) with the weight (200-250 grams) were divided into 2 groups (group A (n = 9) Wistar DM + incision divided into 3 groups, each with 3 rats and group B (n = 9) Non-DM Wistar + incision divided into 3 groups of each 3 rats). Furthermore Wistar rat wounded in the back left and right using 8 mm punch biopsy. 7.5% topical Red Dragon Fruit Extract cream was applied to the surface of the wound with the cotton bud. Tissue preparat colored with Hematoxylin and Eosin (HE) then the wound healing parameters were assessed; the thickness of the granulation tissue and epithelialization with histopathology assessment. Data were analyzed using independent T test and paired T test (SPSS 21, Chicago Inc.) Granulation scores tend to be better at a concentration of 7.5% in the topical Red Dragon Fruit Extract than the negative control group for DM (p <0.068) and non-DM (p <0.034). Epithelialization Scores are better at concentrations of 7.5% in Topical Red Dragon Fruit Extract group than the negative control group for DM (p <0.034) and non DM (p <0.034). Topical Red Dragon Fruit Extract 7.5% increase the growth of granulation tissue and epithelialization in wound healing of acute non-DM and DM at Wistar rats.

Published
2017

12. The Effect of the Extracts of Betel (Piper betel) Leaves on the Content of IL-1? as the Inflammatory Cytokine in Experimental Mice Using an Acute Wound Healing Modeling

Author

Maryunis, Maryunis, Bakri, Syakib, Patellongi, Ilhamjaya, Aman, Makbul, Tahir, Takdir, Syam, Azniah, Maryunis, Maryunis, Bakri, Syakib, Patellongi, Ilhamjaya, Aman, Makbul, Tahir, Takdir, and Syam, Azniah

Abstract

This study aims to determine the effect of ethyl acetate derived from the leaves extraction of betel (Piper betel) on the content of Interleukin-1? (IL-1?) in experimental mice using an acute wound healing modeling. The experimental design used randomized post test only group with 72 experimental mice which divided into 4 groups and each group consisted of 6 mice with three replications. The negative control group (I) was given vaseline after incision. The positive control group (II) was given bioplasenton. The third group (III) was topically given the extracts of betel leaves at 2% concentration and the fourth group (IV) was given the extracts of betel leaves at 3% concentration after incision respectively. The determination of IL-1? applied Immunoassay Quantikine Elisa (IQE). The quantitative analysis (statistical test) used complete randomized design using one-way anova with Spearman

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results