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Alphitonia excelsa merupakan salah satu tanaman yang berpotensi sebagai antioksidan dan telah digunakan secara turun temurun di masyarakat sebagai terapi berbagai macam penyakit. Hal tersebut mendasari tujuan penelitian ini, yaitu menentukan aktivitas antioksidan dan total flavonoid kulit batang A. excelsa. Metode yang di gunakan dalam pengujian antioksidan adalah peredaman terhadap radikal 2,2-difenil-1-pikrilhidrazil (DPPH), sedangkan pengujian flavonoid total dengan AlCl3 dilakukan secara kolorimetri. Hasil yang didapatkan dari penelitian ini adalah nilai IC50 aktivitas antioksidan A. excelsa sebesar 37,00 ± 1,46 μg/ml (bpj) dan flavonoid total senilai 1,17% ± 0.04 QE (quercetin equivalent). Berdasarkan nilai tersebut dapat disimpulkan bahwa kulit batang A. excelsa memiliki kemampuan antioksidan yang sangat kuat. Alphitonia excelsa is a plant that potential to be tested for its antioxidant ability and has been used as medicine. This underlies the purpose of this study, namely to determine the antioxidant activity and total flavonoids of the stem bark of A. excelsa. The method used in antioxidant evaluaion was 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, while the total flavonoid assay with AlCl3 was carried out colorimetrically. The results obtained from this study were the IC50 value of the antioxidant activity and total flavonoids of A. excelsa, with the value of 37.00 ± 1.46 μg/ml and 1.17% ± 0.04 quercetin equivalent, respectively. Based on these values, it can be concluded that the stem bark of A. excelsa has a very strong antioxidant capacity.

Daun cempedak (Artocarpus integer) dimanfaatkan secara tradisional oleh masyarakat Kalimantan Selatan dalam pengobatan. Golongan fenolik terkandung dalam ekstrak daun cempedak dan memiliki kemampuan sebagai antioksidan. Fraksi dari ekstrak daun cempedak belum pernah ditetapkan kadar fenolik total dan akivitas antioksidannya. Penelitian ini bertujuan untuk mengetahui fraksi dari ekstrak daun cempedak yang mengandung kadar fenolik dan aktivitas antioksidan tertinggi. Penelitian dimulai dengan pengeringan daun segar menggunakan lemari pengering, pembuatan serbuk simplisia, proses ekstraksi secara maserasi, pengeringan ekstrak dengan lemari pengering, dan proses fraksinasi dengan pelarut n-heksan, etil asetat dan aquadest. Penetapan kadar fenolik total dapat dilakukan dengan reagen Folin-Ciocalteu dan menggunakan baku pembanding asam galat. Aktivitas antioksidan dilakukan menggunakan metode DPPH berdasarkan nilai IC50 dan dengan pembanding kuersetin. Kadar fenolik total pada fraksi n-heksan 9,352 ± 0,113% b/b, fraksi etil asetat 12,595 ± 0,415% b/b, dan fraksi aquadest 9,992 ± 0,485% b/b ekivalen asam galat. Fraksi n-heksan, etil asetat, dan aquadest masing-masing memiliki nilai IC50 sebesar 89,192 ± 2,91 bpj (kuat), 64,754 ± 2,803 bpj (kuat), dan 82,247 ± 23,034 bpj (kuat). Kesimpulan dari penelitian ini bahwa fraksi etil asetat memiliki kadar fenolik total tertinggi dan aktivitas antioksidan paling kuat dibandingkan fraksi n-heksan dan fraksi aquadest dari ekstrak daun cempedak. Cempedak (Artocarpus integer) leaves are traditionally used by people in South Kalimantan as medicine. The phenolic group contained in cempedak leaf extract has known as an antioxidant. The fraction of cempedak leaf extract has never been determined for total phenolic content and antioxidant activity. This study aimed to determine the fraction of cempedak leaf extract that contains the highest levels of phenolic and antioxidant activity. The study started with drying of fresh leaves using a drying cabinet, simplicia powder preparation, maceration extraction, extract drying, and fractionation with n-hexane, ethyl acetate and aquadest as solvents. Determination of total phenolic content was obtained with Folin-Ciocalteu reagent and gallic acid as a standard for comparison. Antioxidant activity was measured using the DPPH method based on the IC50 value and comparison with quercetin. The total phenolic content of the n-hexane, ethyl acetate and aquadest fraction were 9.352 ± 0.113% w/w, ethyl acetate fraction 12.595 ± 0.415% w/w, and aquadest fraction 9.992 ± 0.485% w/w equivalent gallic acid, respectively. The n-hexane, ethyl acetate, and aquadest fractions showed IC50 values of 89.192 ± 2.91 ppm (strong), 64.754 ± 2.803 ppm (strong), and 82.247 ± 23.034 ppm (strong), respectively. The conclusion of this study was that the ethyl acetate fraction had highest total phenolic content and strongest antioxidant activity compared to n-hexane and aquadest fraction from cempedak leaf extract.

Thematic Real Work Lecture (KKN-T) is a form of implementation of an independent campus. Through this KKN-T activity, it seeks to improve the competence and role of students as agents of change in society, foster a spirit of volunteerism and be able to be responsible for the community. The implementation of KKN-T for the Mambulau village group was carried out in Mambulau Village, Kapuas Hilir District, Kapuas Regency, Central Kalimantan. The approach used in community service activities is participatory action research (PAR). The method of implementing KKN-T is carried out through posyandu and immunization activities, and counseling on the dangers of COVID-19 to the community. Supported by village officials and RT heads. The work program "Efforts to Prevent the Spread of Covid-19 and Micro and Small Enterprises (UMK) in Mambulau Village" has been successfully implemented and smoothly. The people in the Mambulau sub-district were greatly helped by the activities to prevent the spread of COVID-19 carried out at the Posyandu. We also distributed paper bags containing masks and hand sanitizers, held socialization of nose washing at the Posyandu, then posted handwashing posters at places of worship, schools, sub-district offices, and health centers. People in the Mambulau village mostly plant banana trees around their home yards. So that a lot of post-harvest banana stem waste is found that is not utilized. Banana stem waste can be processed into chips. Banana stem chips have the potential to be used as a product for micro and small businesses that can improve the economy of the community in the Mambulau village.

Penelitian ini bertujuan untuk mengetahui pengaruh dukungan sosial terhadap burnout pada atlet taekwondo senior. Penelitian ini menggunakan metode kuantitatif. Sampel dalam penelitian ini sebanyak 175 responden yang merupakan atlet taekwondo senior berusia 18-27 tahun dengan menggunakan teknik purposive sampling. Alat ukur dukungan sosial dalam penelitian ini mengadaptasi dari skala Zimet dkk., (1988) yaitu Multidimensional Scale Perceived Of Social Support (MSPSS) dengan menyesuaikan topik penelitian. Untuk alat ukur burnout pada penelitian ini mengadaptasi skala yang disusun oleh Raedeke & Smith (2001) yaitu The Athlete Burnout Questionnaire (ABQ) dengan menyesuaikan topik penelitian ini. Uji hipotesis yang digunakan untuk penelitian ini adalah analisis regresi linear sederhana. Skala dukungan sosial merupakan skala multidimensi dan memiliki hasil uji reliabilitas sebesar 0,846-0,925. Untuk alat ukur burnout merupakan skala multidimensi dan menunjukkan hasil reliabilitas sebesar 0,827-0,942. Hasil uji hipotesis menunjukkan nilai p (sig) sebesar 0,000 < α (0,05) dan nilai F hitung sebesar 138,780 > F tabel 3,90 dengan R Square 0,445 yang berarti adanya pengaruh dukungan sosial terhadap burnout pada atlet taekwondo senior sebesar 44,5%. Hasil penelitian menunjukkan adanya arah pengaruh negatif, apabila dukungan sosial rendah maka burnout yang dirasakan atlet akan tinggi, dan apabila dukungan sosial tinggi maka burnout yang dirasakan atlet akan rendah. This research aims to find out the effect of social support on burnout at senior taekwondo athletes. This research uses a quantitative research method. There are 175 respondent samples in senior taekwondo athletes using a purposive sampling technique. The measuring instrument for social support in this study adapted the scale of Zimet et al. (1988), namely the Multidimensional Scale Perceived Of Social Support (MSPSS) by adjusting the research topic. The burnout measuring instrument in this study adapted the scale compiled by Raedeke & Smith (2001), namely The Athlete Burnout Questionnaire (ABQ) by adjusting the topic of this research. The hypothesis testing used for this research is simple linear regression analysis. The social support scale is a multidimensional scale and has a reliability result of 0.846-0.925. The burnout measuring instrument is a multidimensional scale and shows a reliability result of 0.827-0.942. The results of the hypothesis test shows the score of p (sig) in the amount of 0.000 < α (0.05) and the score of F value in the amount 138.780 > F table 3.90 with an R Square 0.445 which means that there is an effect of social support on burnout in senior taekwondo athletes of 44.5 % percentages. The results indicated social support was negatively affect athlete burnout, if social support is low, the burnout felt by athletes will be high, and if social support is high, the burnout felt by athletes will be low.

Tujuan dari penelitian ini adalah untuk melihat hubungan dukungan pasangan (istri) dalam pengasuhan dengan paternal involvement pada ayah yang memiliki bayi usia 0-12 bulan. Metode dalam penelitian ini adalah desain kuantitatif korelasional yang menggunakan analisis Pearson Product Moment. Pengumpulan data dilakukan dengan menggunakan skala yang telah diadaptasi ke dalam Bahasa Indonesia oleh Putri (2022) dari alat ukur Paternal Involvement with Infants Scale (α = 0,926) dan menggunakan skala yang diadaptasi dari alat ukur Partner Parental Support Questionnaire (α = 0,943). Responden berjumlah 104 ayah baru yang memiliki bayi usia 0-12 bulan dengan menggunakan teknik quota sampling. Berdasarkan hasil analisis korelasi Pearson Product Moment menunjukkan adanya korelasi positif signifikan dengan nilai koefesien korelasi (r) sebesar 0,278 (sig. (p) = 0,004). Hasil penelitian ini menunjukkan bahwa terdapat hubungan positif antara dukungan pasangan (istri) dalam pengasuhan dengan paternal involvement pada ayah yang memiliki bayi usia 0 – 12 bulan. Jadi, dapat disimpulkan bahwa semakin tinggi dukungan pasangan (istri) dalam pengasuhan maka akan semakin tinggi paternal involvement pada ayah yang memiliki bayi usia 0-12 bulan.

Nuclear factor kappa B (NF-κB) is a transcription factor that regulates the expression of genes important for innate and adaptive immune responses. NF-κB overactivation is associated with inflammatory diseases such as autoimmune, systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). This study aims to screen the chemical content of C.indicum against NF-κB-inducing kinase inhibitors. There are two methods used in this study, namely through PASSonline and docking. The docking method used was PLANTS. The results of PASSonline compounds that have P.a values above 0.7 weree arachidonic acid, linoleic acid, rutin, methyl urasolate, while the docking scores obtained were asquisqualic acid: -60.0382; arachidonic acid : -100,9410; linoleic acid: -93.8730; routine : -102,9320; methyl urasolate: -47,9166. This negative docking score indicates that the reaction between the compound and the target occurs easily. In conclusion, the compound predicted to have a potential as an inhibitor of NF-κB is Rutin.

This study aims to: (1) analyze the level of community participation in the development of ecotourism referrals; (2) analyze what factors are related to the level of community participation in the development of referred ecotourism; (3) analyze what strategies can be applied to increase community participation in the development of ecotourism referrals. The research method used in this research is descriptive method. The research was conducted in Kerujuk Hamlet, Mengala Village which was selected by purposive sampling with the consideration that the hamlet has an ecotourism program that involves the community. The determination of the number of respondents was determined by proportionate stratified random sampling using the Slovin formula and the number of respondents was determined to be 43 respondents. The collected data was then analyzed using a scoring system, Spearman rank correlation test analysis and SWOT analysis. The results showed that the level of community participation was included in the low category because community involvement was still lacking in all stages of activities carried out in an effort to develop ecotourism referrals. Factors related to the level of community participation are non-formal education (skills), income, length of stay and age. The strategy that can be applied in an effort to increase community participation is the WO strategy or weakness-opportunity, where cooperative efforts with the government or educational institutions are carried out to improve the quality of human resources to be more independent in managing creative and innovative referral ecotourism.

One of the fermented milk products, namely kefir, is increasingly popular because it has many health benefits. Peanut juice has a high enough protein content that it can be used as a substitute for animal milk. The purpose of this study was to determine the quality of peanut kefir with variations in the concentration of ragi tape inoculum and fermentation time. This research method used 3 variations in the concentration of tape yeast (1, 2 and 4%) and long fermentation time (24, 48 and 72 hours). The results showed that the highest total LAB was in 4% ragi tape inoculum with a fermentation time of 24 hours (4.4x108 cells/mL) and the lowest was in 4% tape yeast inoculum with a fermentation time of 72 hours (9.8x107 cells/mL) and total yeast between 1x104 cells/mL - 3x105 cells/mL) and alcohol produced

Melati belanda flowers have two varieties that look different, namely from the shape of the flowers. The first variety has the shape of an elongated flower and the second variety has the shape of a rounded flower. So that, this difference in the shape of the flower will allow generating different activities. The purpose of this study was to identify the distinctive spectra of these two varieties. The method used is a fingerprint analysis of UV-VIS spectroscopy combined with chemometrics for the identification and authentication of varieties of Melati belanda. The results of the analysis of PLSR Combretum indicum Varr. B against Combretum indicum Varr. M on a spectrum of 218.86-252.54 nm, The first derivatization of RMSEC 2.39; R2 0.9975; RMSEP 6.92; R2 0.9939 and RMSEC 5.63; R2 0.9868. Meanwhile, with a wavelength of 253,260 – 299,020, a normal model of RMSEC 2.01 was obtained; R2 0.9983; RMSEP 1.89; R2 0.9985 and RMSEC 1; R2 0.9772. So can be concluded below UV-VIS spectroscopic fingerprint analysis combined with chemometrics is able to identify the authentication of the Combretum Indicum Varr. B against the occurrence of adulteration of flowers Combretum Indicum Varr. M at a wavelength of 253.260 – 299.020 nm of normal models.

Combertum indicum has two varieties, namely varr.M and Varr.B., so to maintain the truth of the sample it is necessary to discriminate. The way to distinguish these two varieties can use the UV-vis spectrophotometric approach. The method used in chemometrics uses five sampling districts, namely Banjarmasin, Banjarbaru, Banjar, Tanah Laut, Tanah Spice, the equipment used is spectrophotometry UV-vis. Data analysis uses descriptive analysis. The results of the identification of flower performance index obtained are 88.9; Leave identification 92.2; stem identification 86.8. In conclusion, the combination chemometric UV-vis spectrophotometry succeeded in differentiating combertum indicum varr.M and Varr.B.

The development of technology has initiated new teaching systems. In teaching speaking, there are issues about whether the students should learn in the class or outside of the class using technology. This article describes the practice of students' digital English literacy practice at SMAN Kapuas to study this digital practice's pedagogical potential when students interact directly or through social networks such as live streaming on YouTube or Instagram, video calls, or chatting with friends. A mixed-method study using questionnaires and interviews analyzed deeper and richer data. The results show that many sentences were still wrong when spoken in class. However, they can understand speaking lessons based on digital literacy, which they play or watch outside of the class. This implied that students should be instructed in alternative speaking methods. They may enhance their speaking abilities more purposefully, carefully, and often by using suitable language acquisition tools outside of the class.

Nymphaea pubescens Willd telah diketahui mempunyai efek antibakteri, terutama pada biji dan daunnya. Tetapi sampai saat ini bagian bunga dari tanaman tersebut belum dilakukan pengujian aktivitas antibakteri. Tujuan dari penelitian ini untuk melakukan skrining fitokimia, uji aktivitas antibakteri dan penentuan konsentrasi hambat minimum (KHM) dari ekstrak metanol bunga N. pubescens terhadap S. aureus dan E. coli . Proses ekstraksi bunga N. pubescens dimaserasi menggunakan pelarut metanol dengan perbandingan 1: 4 b/v. Metode pengujian yang digunakan ada dua yaitu metode difusi untuk pengujian aktivitas antibakteri dan metode dilusi untuk pengukuran konsentrasi hambat minimum (KHM). Hasil skrining fitokimia didapatkan bahwa ekstrak metanol bunga N. pubescens mengandung senyawa golongan fenolik, saponin dan flavonoid. Hasil pengujian aktivitas antibakteri menunjukkan bahwa ekstrak metanol bunga N.pubescens mampu menghambat S. aureus (diameter hambat 10 ± 0,29 mm) dan E.coli (diameter hambat 10,2 ± 0,50 mm). Konsentrasi hambat minimum dari ekstrak metanol bunga N. pubescens terhadap S.aureus sebesar 12,5% dan terhadap E.coli sebesar 25%. Dapat disimpulkan bahwa ekstrak metanol bunga N. pubescens memiliki aktivitas sebagai antibakteri. Nymphaea pubescens Willd has known to have antibacterial effects, especially on the seeds and leaves. However, until now the flower of the plant has not been tested for antibacterial activity. The purpose of this study was to perform phytochemical screening, antibacterial activity test and determine the minimum inhibitory concentration (MIC) of the methanol extract of N. pubescens flowers against S. aureus and E. coli. The process of extracting N. pubescens flowers is macerated using methanol as a solvent with a ratio of 1: 4 w / v. There are two test methods used, namely the diffusion method for testing antibacterial activity and the dilution method for measuring the minimum inhibitory concentration (MIC). The results of phytochemical screening showed that the methanol extract of N. pubescens flowers contained phenolic compounds, saponins, and flavonoids. The results of the antibacterial activity test showed that the methanol extract of N.pubescens flowers was able to inhibit S. aureus (inhibition diameter 10 ± 0.29 mm) and E. coli (inhibitory diameter 10.2 ± 0.50 mm). The minimum inhibitory concentration of the methanol extract of N. pubescens flowers against S.aureus was 12.5% and against E. coli was 25%. It can be concluded that the methanol extract of N. pubescens flowers has antibacterial activity Keywords : Nymphaea pubescens, lotus flower, methanol extract, antibacterial

Pasak bumi sebagai obat tradisional pria telah digunakan oleh masyarakat melayu, khususnya orang Sumatra dan kalimantan, akan tetapi mekanisme secara molekuler belum dikatahui dengan jelas. Salah satu pendekatan yang dapat digunakan untuk mengetahui mekanisme pasak bumi sebagai obat tradisional yang bermanfaat mengatasi disfungsi ereksi adalah penambatan molekul. Penambatan melekul dilakukan dengan cara melihat interaksi ligand dengan reseptor. Ligand yang berasal dari pasak bumi adalah 5-methoxycanthin-6-one, 9-methoxycanthin-6-one, eurycomalactone, eurycomalide A, eurycomanone, eurycomaoside, laurycolactone A, longilactone, niloticin, picrasidine O. Sehingga kesepuluh ligand ini didocking menggunakan salah satu aplikasi docking yaitu PLANTS 1.1 untuk melihat ikatan dengan PDE5. Sebelum dilakukan docking terhadap ligand pasak bumi, terlebih dahulu dilakukan docking terhadap ligand Sildenafil untuk melhat nilai RMSD. RMSD ini diperlukan sebagai alat validasi metode, berdasarkan percobaan, nilai RMSD dari Sildenafil adalah 1,2517 A0. Hasil terbaik dari penambatan molekul pasak bumi adalah niloticin dengan skor doking -97,8802, sehingga nilai interaksinya terhadap reseptor sebesar 93,71% dari Sildenafil.Pasak bumi as traditional male medicine has been used by Malay people, especially Sumatra and Borneo people, but the molecular mechanism is not yet known clearly. One approach that can be used to determine the mechanism of the Pasak Bumi as a traditional medicine that is useful to overcome erectile dysfunction is docking molecules. Molecular docking is done by looking at the interaction of ligands with receptors. Ligands originating from the Pasak Bumi are 5-methoxycanthin-6-one, 9-methoxycanthin-6-one, eurycomalactone, eurycomalide A, eurycomanone, eurycomaoside, laurycolactone A, longilactone, niloticin, picrasidine O. docking application namely PLANTS 1.1 to see the bond with PDE5. Before docking Pasak Bumi ligand, it is first docking Sildenafil ligand to see the RMSD value. The RMSD is needed as a method validation method, based on experiments, the RMSD value of Sildenafil is 1.2517 A0. The best results from docking of the Pasak bumi molecule is niloticin with a doctor score of -97.8802, so interaction skor to the receptor is 93.71% of Sildenafil.Keywords: Pasak Bumi, PDE5, PLANTS