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2. Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review

Author

Roberto Céspedes López, Elena Amutio Díez, Xabier Martín Martitegui, Amaia Balerdi Malcorra, Lucia Insunza Oleaga, Javier Arzuaga‐Méndez, Maite Moreno Gámiz, Mónica Saiz Camín, Yoseba Aberasturi Plata, and Juan Carlos García‐Ruíz

Subjects
agranulocytosis, granulocytopenia and good's syndrome, pure white cell aplasia, thymoma, Medicine, Medicine (General), R5-920
Abstract

Abstract Thymomas are tumours frequently associated with autoimmune manifestations or immunodeficiencies like Good syndrome. In rare cases, pure white cells aplasia (PWCA) has been described in association with thymomas. PWCA is characterized by agranulocytosis of autoimmune background primary refractory to granulocyte colony‐stimulating factor (G‐CSF). It is necessary the use of immunosuppressor to allow granulocyte recovery. Without treatment, it could be fatal.

Published
2022
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3. Pure White Cell Aplasia an exceptional condition in the inmunological conundrum of thymomas: Responses to inmunosupresion and Literature Review

Author

Roberto Céspedes López, Elena Amutio, Xabier Martín Martitegui, Amaia Balerdi Malcorra, Lucia Insunza Oleaga, Maite Moreno, Javier Arzuaga-Mendez, and Juan García-Ruiz

Subjects
hemic and lymphatic diseases
Abstract

Thymomas are tumours frequently associated with autoinmune manifestations or immunodeficiencies like Good syndrome. In rare cases, pure white cells aplasia (PWCA) has been described in association with thymomas. PWCA is characterized by agranulocytosis of autoinmune background primary refractory to granulocyte colony-stimulating factor (G-CSF). It is necessary to use inmunosupressor drugs.

Published
2021

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