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This research was conducted as a descriptive study for the purpose of determining nurses' attitudes towards their profession and the factors influencing their attitudes. A purposeful sampling technique was used to make selection from 15 hospitals in total. A quota sampling method was used to determine the number of nurses, and initially, it was planned to include 1000 nurses from private and public hospitals in the study; however, valid data was obtained from 834 nurses. A 17-item questionnaire was used to determine the respondents' opinions about the profession. In addition, a 55-item scale was used to collect data regarding the nurses' attitudes towards their profession, as well. Frequency distribution, percentage calculation, One way ANOVA, t-test, Kruskal-Wallis and Tukey HSD were used in the analysis of the data. As a result of the study, nurses had 164 point on average in the 55-item scale, and accordingly, certain personal and professional factors like education level, position at work, professional experience and the employer institute were found to affect nurses' attitudes towards their profession. [ABSTRACT FROM AUTHOR]