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1. Epidemiological analysis of the victıms wıth crush syndrome in earthquakes of southeastern Turkey

Author

Ozturk, Ilyas, Gungor, Ozkan, Ozturk, Savas, Olmaz, Refik, Keskin, Ayse Jini Gunes, Kocyigit, Ismail, Sipahioglu, Murat Hayri, Dede, Fatih, Ulu, Sena, Turgutalp, Kenan, Torun, Dilek, Sahutoglu, Tuncay, Erdur, Fatih Mehmet, Altunoren, Orcun, Danis, Ramazan, Yildiz, Gursel, Gurel, Ali, Horoz, Mehmet, Kucuksu, Mehmet, Karakose, Suleyman, Yildirim, Tolga, Altiparmak, Mehmet Riza, Ayli, Mehmet Deniz, Tugcu, Murat, Eren, Zehra, Eroglu, Eray, Yavuz, Yasemin Coskun, Akcali, Esra, Sit, Dede, Polat, Mehmet, Yildirim, Saliha, Alagoz, Selma, Bek, Sibel Gokcay, Pembegul, Irem, Karaaslan, Tahsin, Keles, Mustafa, Sari, Funda, Yilmaz, Ustun, Gorgulu, Numan, Sahin, Gulizar, Aydin, Zeki, Yadigar, Serap, Ulutas, Ozkan, Selcuk, Nedim Yilmaz, Ayar, Yavuz, Turgut, Didem, Oto, Ozgur Akin, Koc, Mehmet, Yıldız, Alaattin, Tuglular, Serhan, and Sever, Mehmet Sukru

Published
2024
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4. Could mesangial C3 deposition be an independent prognostic marker in immunoglobulin A nephropathy?

Author

Cetinkaya, Hakki, Gursu, Meltem, Yazici, Halil, Cebeci, Egemen, Eren, Necmi, Altiparmak, Mehmet Riza, Akcay, Omer Faruk, Sahin, Gulizar, Dheir, Hamad, Basturk, Taner, Atilgan, Kadir Gokhan, Aydemir, Nihal, Turgutalp, Kenan, Yilmaz, Murvet, Sirali, Semahat Karahisar, Tatar, Erhan, Boz, Elif Gullulu, Mirioglu, Safak, Kazan, Sinan, Aydin, Emre, Aydin, Zeki, Turkmen, Kultigin, Kutlay, Sim, Karagoz, Ferdi, Ogutmen, Melike Betul, Ozturk, Savas, Ozkan, Oktay, Yildiz, Nuriye, Dincer, Tamer, Yasar, Emre, Gok, Mahmut, Turkmen, Aydın, Dede, Fatih, and Derici, Ulver

Published
2024
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8. Results from part A of the multi-center, double-blind, randomized, placebo-controlled NefIgArd trial, which evaluated targeted-release formulation of budesonide for the treatment of primary immunoglobulin A nephropathy

Author

Fragale, Guillermo, Karl, Alejandra, Losisolo, Patricia, Trimarchi, Hernán, Hoyos, Ivan Gonzalez, Lampo, Mauro Guillermo, Monkowski, Matias, De La Fuente, Jorge, Alvarez, Magdalena, Stoppa, Daniela, Chiurchiu, Carlos, Novoa, Pablo Antonio, Orias, Marcelo, Barron, Maria Belen, Giotto, Ana, Arriola, Mariano, Cassini, Evelin, Maldonado, Rafael, Dionisi, Maria Paula, Ryan, Jessica, Toussaint, Nigel, Luxton, Grant, Peh, Chen Au, Levidiotis, Vicki, Francis, Ross, Phoon, Richard, Fedosiuk, Elena, Toropilov, Dmitry, Yakubtsevich, Ruslan, Mikhailova, Elena, Bovy, Christophe, Demoulin, Nathalie, Hougardy, Jean-Michel, Maes, Bart, Speeckaert, Marijn, Laurin, Louis-Philippe, Barbour, Sean, Masse, Melanie, Hladunewich, Michelle, Reich, Heather, Cournoyer, Serge, Tennankore, Karthik, Lv, Jicheng, Liu, Zhangsuo, Wang, Caili, Li, Shaomei, Luo, Qun, Ni, Zhaohui, Yan, Tiekun, Fu, Ping, Cheng, Hong, Liu, Bicheng, Lu, Wanhong, Wang, Jianqin, Chen, Qinkai, Wang, DeGuang, Xiong, Zuying, Chen, Menghua, Xu, Yan, Wei, Jiali, Pai, Pearl, Chen, Lianhua, Rehorova, Jitka, Maixnerova, Dita, Safranek, Roman, Rychlik, Ivan, Hruby, Miroslav, Makela, Satu, Vaaraniemi, Kati, Ortiz, Fernanda, Alamartine, Eric, Daroux, Maite, Cartery, Claire, Vrtovsnik, Francois, Serre, Jean-Emmanuel, Stamellou, Eleni, Vielhauer, Volker, Hugo, Christian, Budde, Klemens, Otte, Britta, Nitschke, Martin, Ntounousi, Evangelia, Boletis, Ioannis, Papagianni, Aikaterini, Goumenos, Dimitrios, Stylianou, Konstantinos, Zermpala, Synodi, Esposito, Ciro, Cozzolino, Mario Gennaro, Viganò, Sara Maria, Gesualdo, Loreto, Nowicki, Michal, Stompor, Tomasz, Kurnatowska, Ilona, Kim, Sung Gyun, Kim, Yong-Lim, Na, Ki-Ryang, Kim, Dong Ki, Kim, Su-Hyun, Porras, Luis Quintana, Garcia, Eva Rodriguez, Pamplona, Irene Agraz, Segarra, Alfons, Goicoechea, Marian, Fellstrom, Bengt, Lundberg, Sigrid, Hemmingsson, Peter, Guron, Gregor, Sandell, Anna, Chen, Cheng-Hsu, Tokgoz, Bulent, Duman, Soner, Altiparmak, Mehmet Riza, Ergul, Metin, Maxwell, Peter, Mark, Patrick, McCafferty, Kieran, Khwaja, Arif, Cheung, Chee Kay, Hall, Matthew, Power, Albert, Kanigicherla, Durga, Baker, Richard, Moriarty, Jim, Mohamed, Amr, Aiello, Joseph, Canetta, Pietro, Ayoub, Isabelle, Robinson, Derrick, Thakar, Surabhi, Mottl, Amy, Sachmechi, Isaac, Fischbach, Bernard, Singh, Harmeet, Mulhern, Jeffrey, Kamal, Fahmeedah, Linfert, Douglas, Rizk, Dana, Wadhwani, Shikha, Sarav, Menaka, Campbell, Kirk, Coppock, Gaia, Luciano, Randy, Sedor, John, Avasare, Rupali, Lau, Wai Lang, Barratt, Jonathan, Lafayette, Richard, Kristensen, Jens, Stone, Andrew, Cattran, Daniel, Floege, Jürgen, Tesar, Vladimir, Zhang, Hong, Eren, Necmi, Paliege, Alexander, and Rovin, Brad H.

Published
2023
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9. The Longitudinal Evolution of Post–COVID-19 Outcomes Among Hemodialysis Patients in Turkey

Author

Ozturk, Savas, Turgutalp, Kenan, Arici, Mustafa, Gorgulu, Numan, Tonbul, Halil Zeki, Eren, Necmi, Gencer, Vedat, Ayli, Mehmet Deniz, Pembegul, Irem, Dolarslan, Murside Esra, Ural, Zeynep, Colak, Hulya, Ozler, Tuba Elif, Can, Ozgur, Demir, Mehmet Emin, Altunoren, Orcun, Huddam, Bulent, Onec, Kursad, Demirelli, Bulent, Aydin, Zeki, Altun, Eda, Alagoz, Selma, Ayar, Yavuz, Eser, Zeynep Ebru, Berktas, Bayram, Yilmaz, Zulfukar, Ates, Eser Uslu, Yuksel, Enver, Sahin, Gizem Kumru, Aktar, Merve, Cebeci, Egemen, Dursun, Belda, Kocak, Sibel Yucel, Yildiz, Abdulmecit, Kazan, Sinan, Gok, Mahmut, Sengul, Erkan, Tugcu, Murat, Ozturk, Ramazan, Kahvecioglu, Serdar, Kara, Ekrem, Kaya, Bulent, Sahin, Garip, Sakaci, Tamer, Sipahi, Savas, Kurultak, Ilhan, Durak, Beyza Algul, Altiparmak, Mehmet Riza, Ecder, Sabahat Alisir, Karadag, Serhat, Dincer, Mevlut Tamer, Ozer, Hakan, Bek, Sibel Gokcay, Ulu, Memnune Sena, Gungor, Ozkan, Bakir, Elif Ari, Odabas, Ali Riza, Seyahi, Nurhan, Yildiz, Alaattin, and Ates, Kenan

Published
2022
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11. Patients with crush syndrome and kidney disease: lessons learned from the earthquake in Kahramanmaraş, Türkiye

Author

Ozturk, Savas, Tuglular, Serhan, Olmaz, Refik, Kocyigit, Ismail, Kibar, Muge Uzerk, Turgutalp, Kenan, Torun, Dilek, Sahutoglu, Tuncay, Usalan, Ozlem, Gungor, Ozkan, Danis, Ramazan, Yildiz, Gursel, Gurel, Ali, Horoz, Mehmet, Kucuksu, Mehmet, Karakose, Suleyman, Yildirim, Tolga, Altiparmak, Mehmet Riza, Ayli, Mehmet Deniz, Tugcu, Murat, Eren, Zehra, Eroglu, Eray, Yavuz, Yasemin Coskun, Akcali, Esra, Sit, Dede, Polat, Mehmet, Yildirim, Saliha, Alagoz, Selma, Bek, Sibel Gokcay, Pembegul, Irem, Karaaslan, Tahsin, Keles, Mustafa, Sari, Funda, Inci, Ayca, Gorgulu, Numan, Sahin, Gulizar, Aydin, Zeki, Yadigar, Serap, Ulutas, Ozkan, Selcuk, Nedim Yilmaz, Ayar, Yavuz, Bal, Zeynep, Altunok, Murat, Günes Keskin, Ayse Jini, Sipahioglu, Murat Hayri, Ozkutlu, Meliha, Dursun, Belda, Oruc, Aysegul, Hasbal, Nuri Baris, Sevinc, Mustafa, Gul, Semih, Ozturk, Seda Safak, Yildiz, Alaattin, and Sever, Mehmet Sukru

Abstract

This study investigated in-hospital outcomes and related factors in patients diagnosed with postearthquake crush syndrome after the earthquakes in Kahramanmaraş, Türkiye. One thousand twenty-four adult patients diagnosed with crush syndrome were analyzed. Data on demographic characteristics, clinical presentation, laboratory values, treatments, and outcomes were collected. A total of 9.8% of patients died during their hospital stay. Nonsurvivors were generally older, more likely to have preexisting chronic kidney disease, and faced more severe injuries and complications, including hypotension-shock, arrhythmias, elevated markers of renal dysfunction, and higher rates of acute kidney injury (AKI) and compartment syndrome. In addition, intensive care unit needs were higher. Multivariate analysis confirmed that age, injury severity, shock, high potassium, uric acid, and lactate levels on admission, development of AKI, compartment syndrome, and intensive care unit admission were significant predictors of mortality. Better disaster preparedness and improved health care infrastructure could be potential explanations for improved in-hospital mortality in the current era, as compared to previous earthquakes.

Published
2024
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12. Determinants of mortality in a large group of hemodialysis patients hospitalized for COVID-19

Author

Turgutalp, Kenan, Ozturk, Savas, Arici, Mustafa, Eren, Necmi, Gorgulu, Numan, Islam, Mahmut, Uzun, Sami, Sakaci, Tamer, Aydin, Zeki, Sengul, Erkan, Demirelli, Bulent, Ayar, Yavuz, Altiparmak, Mehmet Riza, Sipahi, Savas, Mentes, Ilay Berke, Ozler, Tuba Elif, Oguz, Ebru Gok, Huddam, Bulent, Hur, Ender, Kazancioglu, Rumeyza, Gungor, Ozkan, Tokgoz, Bulent, Tonbul, Halil Zeki, Yildiz, Alaattin, Sezer, Siren, Odabas, Ali Riza, and Ates, Kenan

Published
2021
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13. Predicting the outcome of COVID-19 infection in kidney transplant recipients

Author

Oto, Ozgur Akin, Ozturk, Savas, Turgutalp, Kenan, Arici, Mustafa, Alpay, Nadir, Merhametsiz, Ozgur, Sipahi, Savas, Ogutmen, Melike Betul, Yelken, Berna, Altiparmak, Mehmet Riza, Gorgulu, Numan, Tatar, Erhan, Ozkan, Oktay, Ayar, Yavuz, Aydin, Zeki, Dheir, Hamad, Ozkok, Abdullah, Safak, Seda, Demir, Mehmet Emin, Odabas, Ali Riza, Tokgoz, Bulent, Tonbul, Halil Zeki, Sezer, Siren, Ates, Kenan, and Yildiz, Alaattin

Published
2021
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15. Could mesangial C3 deposition be an independent prognostic marker in immunoglobulin A nephropathy?

Author

Cetinkaya, Hakki, primary, Gursu, Meltem, additional, Yazici, Halil, additional, Cebeci, Egemen, additional, Eren, Necmi, additional, Altiparmak, Mehmet Riza, additional, Akcay, Omer Faruk, additional, Sahin, Gulizar, additional, Dheir, Hamad, additional, Basturk, Taner, additional, Atilgan, Kadir Gokhan, additional, Aydemir, Nihal, additional, Turgutalp, Kenan, additional, Yilmaz, Murvet, additional, Sirali, Semahat Karahisar, additional, Tatar, Erhan, additional, Boz, Elif Gullulu, additional, Mirioglu, Safak, additional, Kazan, Sinan, additional, Aydin, Emre, additional, Aydin, Zeki, additional, Turkmen, Kultigin, additional, Kutlay, Sim, additional, Karagoz, Ferdi, additional, Ogutmen, Melike Betul, additional, Ozturk, Savas, additional, Ozkan, Oktay, additional, Yildiz, Nuriye, additional, Dincer, Tamer, additional, Yasar, Emre, additional, Gok, Mahmut, additional, Turkmen, Aydın, additional, Dede, Fatih, additional, and Derici, Ulver, additional

Published
2023
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18. #5499 COULD MESANGIAL C3 DEPOSITION BE AN INDEPENDENT PROGNOSTIC MARKER IN IMMUNOGLOBULIN A NEPHROPATHY?

Author

Cetinkaya, Hakki, primary, Gursu, Meltem, additional, Yazici, Halil, additional, Cebeci, Egemen, additional, Eren, Necmi, additional, Altiparmak, Mehmet Riza, additional, Akcay, Omer Faruk, additional, Sahin, Gulizar Manga, additional, Basturk, Taner, additional, Atilgan, Kadir Gokhan, additional, Aydemir, Nihal, additional, Turgutalp, Kenan, additional, Dheir, Hamad, additional, Yılmaz, MÜrvet, additional, Sirali, Semahat Karahisar, additional, Tatar, Erhan, additional, Boz, Saide Elif Gullulu, additional, Mirioglu, Safak, additional, Kazan, Sinan, additional, Aydin, Emre, additional, Aydin, Zeki, additional, Turkmen, Kultigin, additional, Kutlay, Sim, additional, Karagoz, Ferdi, additional, Ogutmen, Melike Betul, additional, Ozturk, Savas, additional, Ozkan, Oktay, additional, Yıldız, Nuriye, additional, Dincer, Mevlut Tamer, additional, Yasar, Emre, additional, Gok, Mahmut, additional, Turkmen, Aydin, additional, Dede, Fatih, additional, and Derici, Ulver, additional

Published
2023
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19. Results from part A of the multi-center, double-blind, randomized, placebo-controlled NefIgArd trial, which evaluated targeted-release formulation of budesonide for the treatment of primary immunoglobulin A nephropathy

Author

Barratt, Jonathan, primary, Lafayette, Richard, additional, Kristensen, Jens, additional, Stone, Andrew, additional, Cattran, Daniel, additional, Floege, Jürgen, additional, Tesar, Vladimir, additional, Trimarchi, Hernán, additional, Zhang, Hong, additional, Eren, Necmi, additional, Paliege, Alexander, additional, Rovin, Brad H., additional, Fragale, Guillermo, additional, Karl, Alejandra, additional, Losisolo, Patricia, additional, Hoyos, Ivan Gonzalez, additional, Lampo, Mauro Guillermo, additional, Monkowski, Matias, additional, De La Fuente, Jorge, additional, Alvarez, Magdalena, additional, Stoppa, Daniela, additional, Chiurchiu, Carlos, additional, Novoa, Pablo Antonio, additional, Orias, Marcelo, additional, Barron, Maria Belen, additional, Giotto, Ana, additional, Arriola, Mariano, additional, Cassini, Evelin, additional, Maldonado, Rafael, additional, Dionisi, Maria Paula, additional, Ryan, Jessica, additional, Toussaint, Nigel, additional, Luxton, Grant, additional, Peh, Chen Au, additional, Levidiotis, Vicki, additional, Francis, Ross, additional, Phoon, Richard, additional, Fedosiuk, Elena, additional, Toropilov, Dmitry, additional, Yakubtsevich, Ruslan, additional, Mikhailova, Elena, additional, Bovy, Christophe, additional, Demoulin, Nathalie, additional, Hougardy, Jean-Michel, additional, Maes, Bart, additional, Speeckaert, Marijn, additional, Laurin, Louis-Philippe, additional, Barbour, Sean, additional, Masse, Melanie, additional, Hladunewich, Michelle, additional, Reich, Heather, additional, Cournoyer, Serge, additional, Tennankore, Karthik, additional, Lv, Jicheng, additional, Liu, Zhangsuo, additional, Wang, Caili, additional, Li, Shaomei, additional, Luo, Qun, additional, Ni, Zhaohui, additional, Yan, Tiekun, additional, Fu, Ping, additional, Cheng, Hong, additional, Liu, Bicheng, additional, Lu, Wanhong, additional, Wang, Jianqin, additional, Chen, Qinkai, additional, Wang, DeGuang, additional, Xiong, Zuying, additional, Chen, Menghua, additional, Xu, Yan, additional, Wei, Jiali, additional, Pai, Pearl, additional, Chen, Lianhua, additional, Rehorova, Jitka, additional, Maixnerova, Dita, additional, Safranek, Roman, additional, Rychlik, Ivan, additional, Hruby, Miroslav, additional, Makela, Satu, additional, Vaaraniemi, Kati, additional, Ortiz, Fernanda, additional, Alamartine, Eric, additional, Daroux, Maite, additional, Cartery, Claire, additional, Vrtovsnik, Francois, additional, Serre, Jean-Emmanuel, additional, Stamellou, Eleni, additional, Vielhauer, Volker, additional, Hugo, Christian, additional, Budde, Klemens, additional, Otte, Britta, additional, Nitschke, Martin, additional, Ntounousi, Evangelia, additional, Boletis, Ioannis, additional, Papagianni, Aikaterini, additional, Goumenos, Dimitrios, additional, Stylianou, Konstantinos, additional, Zermpala, Synodi, additional, Esposito, Ciro, additional, Cozzolino, Mario Gennaro, additional, Viganò, Sara Maria, additional, Gesualdo, Loreto, additional, Nowicki, Michal, additional, Stompor, Tomasz, additional, Kurnatowska, Ilona, additional, Kim, Sung Gyun, additional, Kim, Yong-Lim, additional, Na, Ki-Ryang, additional, Kim, Dong Ki, additional, Kim, Su-Hyun, additional, Porras, Luis Quintana, additional, Garcia, Eva Rodriguez, additional, Pamplona, Irene Agraz, additional, Segarra, Alfons, additional, Goicoechea, Marian, additional, Fellstrom, Bengt, additional, Lundberg, Sigrid, additional, Hemmingsson, Peter, additional, Guron, Gregor, additional, Sandell, Anna, additional, Chen, Cheng-Hsu, additional, Tokgoz, Bulent, additional, Duman, Soner, additional, Altiparmak, Mehmet Riza, additional, Ergul, Metin, additional, Maxwell, Peter, additional, Mark, Patrick, additional, McCafferty, Kieran, additional, Khwaja, Arif, additional, Cheung, Chee Kay, additional, Hall, Matthew, additional, Power, Albert, additional, Kanigicherla, Durga, additional, Baker, Richard, additional, Moriarty, Jim, additional, Mohamed, Amr, additional, Aiello, Joseph, additional, Canetta, Pietro, additional, Ayoub, Isabelle, additional, Robinson, Derrick, additional, Thakar, Surabhi, additional, Mottl, Amy, additional, Sachmechi, Isaac, additional, Fischbach, Bernard, additional, Singh, Harmeet, additional, Mulhern, Jeffrey, additional, Kamal, Fahmeedah, additional, Linfert, Douglas, additional, Rizk, Dana, additional, Wadhwani, Shikha, additional, Sarav, Menaka, additional, Campbell, Kirk, additional, Coppock, Gaia, additional, Luciano, Randy, additional, Sedor, John, additional, Avasare, Rupali, additional, and Lau, Wai Lang, additional

Published
2023
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23. Acute Kidney Injury In Turkey: Epidemiological Characteristics, Etiology, Clinical Course And Prognosis

Author

Gursu, Meltem, primary, Yegenaga, Itir, additional, Tuglular, Serhan, additional, Dursun, Belda, additional, Bek, Sibel Gokcay, additional, Bardak, Simge, additional, Onan, Engin, additional, Demir, Serap, additional, Derici, Ulver, additional, Dogukan, Ayhan, additional, Sevinc, Mustafa, additional, Kocyigit, Ismail, additional, Altun, Eda, additional, Haras, Ali Burak, additional, Altiparmak, Mehmet Riza, additional, and Tombul, Zeki, additional

Published
2022
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24. Characteristics and Survival Results of Peritoneal Dialysis Patients Suffering from COVID-19 in Turkey: A Multicenter National Study

Author

Gursu, Meltem, primary, Ozturk, Savas, additional, Arici, Mustafa, additional, Sahin, Idris, additional, Gokcay Bek, Sibel, additional, Yilmaz, Murvet, additional, Koyuncu, Sumeyra, additional, Karahisar Sirali, Semahat, additional, Ural, Zeynep, additional, Dursun, Belda, additional, Yuksel, Enver, additional, Uzun, Sami, additional, Sipahi, Savaş, additional, Ahbap, Elbis, additional, Artan, Ayse Serra, additional, Altunoren, Orcun, additional, Tunca, Onur, additional, Ayar, Yavuz, additional, Gok Oguz, Ebru, additional, Yilmaz, Zulfukar, additional, Kahvecioglu, Serdar, additional, Asicioglu, Ebru, additional, Oruc, Aysegul, additional, Altiparmak, Mehmet Riza, additional, Aydin, Zeki, additional, Huddam, Bulent, additional, Dolarslan, Murside Esra, additional, Azak, Alper, additional, Bakırdogen, Serkan, additional, Yalcin, Ahmet Ugur, additional, Karadag, Serhat, additional, Ulu, Memnune Sena, additional, Gungor, Ozkan, additional, Ari Bakir, Elif, additional, Odabas, Ali Rıza, additional, Seyahi, Nurhan, additional, Yildiz, Alaattin, additional, and Ates, Kenan, additional

Published
2022
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29. MO371TIME AND THE ETIOLOGY OF ACUTE KIDNEY INJURY DEFINE PROGNOSIS IN THE COURSE OF COVID-19

Author

Murt, Ahmet, Dincer, Mevlut Tamer, Karaca, Cebrail, Trabulus, Sinan, Seyahi, Nurhan, and Altiparmak, Mehmet Riza

Subjects
Mini Orals (sorted by session), Transplantation, Nephrology, AKI. Clinical. Epidemiology and outcome, AcademicSubjects/MED00340, urologic and male genital diseases, female genital diseases and pregnancy complications
Abstract

Background and Aims Kidneys are among the affected organs in COVID-19 and there may be different etiologies resulting in acute kidney injury (AKI) in different stages of the disease. There have been previous studies focusing on incidence and mortality of AKI in COVID-19 but none has made in depth analysis in relation to the background pathophysiology. Based on previous observations, we hypothesized that all AKIs seen in COVID-19 are not uniform and we aimed to analyze the etiologies and prognosis of AKI among hospitalized COVID-19 patients in relation to the time of AKI during different phases of the disease. Method A total of 1056 patients were admitted to the designated COVID-19 clinics from March to July in 2020. 77 Patients who were younger than 18 years old and 7 kidney transplant patients were excluded from the study. 427 of the remaining patients were confirmed by real time polymerase chain reaction (RT-PCR) test.). As eGFR below 60 mL/min/1,73 m2 was already shown to be related to mortality, these patients (44) were also excluded. As immunologic response is generally accepted to start with the second week of COVID-19 course, patients were classified into three groups, those who had AKI on admission, those who developed AKI in the first week and those who developed AKI starting from 7th day. Initial lymphocyte counts, creatinine levels, electrolytes, acid-base status and changes in the inflammatory markers were compared between the groups. A comparison between patients who survived and who died was also performed. Results 89 of the 383 included COVID-19 patients developed AKI. 24% of those who developed AKI died. Patients who developed AKI later had higher peak CRP and D-dimer levels with lower nadir lymphocyte counts (p=0,000, 0,004 and 0,003 respectively). Additionally, patients who died had higher initial inflammatory marker levels and lower lymphocyte counts than those who survived. Mortality of patients who had AKI on hospital admission (13%) was similar to the overall COVID-19 mortality for inpatients, however it was as high as 44% for those who developed AKI after 7th day. Early AKI was related to pre-renal causes and had a milder course. However, later AKIs were more related to immunologic response and had significantly higher mortality. Patients who died had significantly higher ferritin and d-dimer levels upon their hospital admissions (p=0,000). Electrolyte disturbances, metabolic acidosis and mortality were also higher in patients who developed AKI later. Hypernatremia (OR: 6,5, 95% CI: 3 – 13,9) and phosphorus disturbances (both hyperphosphatemia (OR: 3,3; 95%CI: 1,6 – 6,9) and hypophosphatemia (OR: 3,9; 95% CI: 2,0-7,9)) were related to mortality. Conclusion Findings of this study suggest that AKI in COVID-19 is not of one kind. When developed, AKI should be evaluated in conjunction with the disease stage and possible etiologies

Published
2021

30. Characteristics and outcomes of hospitalised older patients with chronic kidney disease and COVID‐19: A multicenter nationwide controlled study

Author

Ozturk, Savas, primary, Turgutalp, Kenan, additional, Arici, Mustafa, additional, Gok, Mahmut, additional, Islam, Mahmud, additional, Altiparmak, Mehmet Riza, additional, Aydin, Zeki, additional, Doner, Baris, additional, Eren, Necmi, additional, Sengul, Erkan, additional, Karadag, Serhat, additional, Ozler, Tuba Elif, additional, Dheir, Hamad, additional, Pembegul, Irem, additional, Guven Taymez, Dilek, additional, Sahin, Garip, additional, Bakirdogen, Serkan, additional, Dolarslan, Murside Esra, additional, Soypacaci, Zeki, additional, Hur, Ender, additional, Kara, Ekrem, additional, Basturk, Taner, additional, Ogutmen, Melike Betul, additional, Gorgulu, Numan, additional, Sahin, Idris, additional, Ayli, Mehmet Deniz, additional, Tuglular, Zubeyde Serhan, additional, Sahin, Gulizar, additional, Tokgoz, Bulent, additional, Tonbul, Halil Zeki, additional, Yildiz, Alaattin, additional, Sezer, Siren, additional, Odabas, Ali Riza, additional, and Ates, Kenan, additional

Published
2021
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35. Kidney function on admission predicts in-hospital mortality in COVID-19

Author

Trabulus, Sinan, Karaca, Cebrail, balkan, ilker, Dincer, Mevlut Tamer, Murt, Ahmet, Ozcan, Seyda Gul, Karaali, Rıdvan, KARAALİ, Rıdvan, Mete, Bilgul, Bakir, Alev, Kuskucu, Mert Ahmet, Altiparmak, Mehmet Riza, Tabak, Fehmi, Seyahi, Nurhan, and İÜC, Cerrahpaşa Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü

Subjects
Male, Viral Diseases, Physiology, 030232 urology & nephrology, Blood Pressure, Comorbidity, Logistic regression, Biochemistry, Vascular Medicine, 0302 clinical medicine, Medical Conditions, Medicine and Health Sciences, 030212 general & internal medicine, Hospital Mortality, Multidisciplinary, COVID-19, C-reactive proteins, Glomerular filtration rate, Kidneys, Intensive care units, Creatinine, Blood pressure, Death rates, Mortality rate, Acute kidney injury, Acute Kidney Injury, Middle Aged, Prognosis, C-Reactive Proteins, Hospitals, Intensive Care Units, Infectious Diseases, Medicine, Female, Anatomy, Coronavirus Infections, Research Article, Glomerular Filtration Rate, Adult, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Death Rates, Science, Pneumonia, Viral, Renal function, 03 medical and health sciences, Population Metrics, Internal medicine, medicine, Humans, Pandemics, Aged, Renal Physiology, In hospital mortality, Population Biology, business.industry, Proportional hazards model, Biology and Life Sciences, Proteins, Covid 19, Odds ratio, Renal System, medicine.disease, Health Care, Health Care Facilities, business, Biomarkers
Abstract

BackgroundRecent data have reinforced the concept of a reciprocal relationship between COVID-19 and kidney function. However, most studies have focused on the effect of COVID-19 on kidney function, whereas data regarding kidney function on the COVID-19 prognosis is scarce. Therefore, in this study, we aimed to investigate the association between eGFR on admission and the mortality rate of COVID-19.MethodsWe recruited 336 adult consecutive patients (male 57.1%, mean age 55.0±15.9) that were hospitalized with the diagnosis of COVID-19 in the tertiary care university hospital. Data were collected from the electronic health records of the hospital. On admission, eGFR was calculated using the CKD-EPI formula. Acute kidney injury was defined according to the KDIGO criteria. Binary logistic regression and Cox regression analyses were used to assess the relationship between eGFR on admission and in-hospital mortality of COVID-19.ResultsBaseline eGFR was under 60 mL/min/1.73m2in 61 patients (18.2%). Acute kidney injury occurred in 29.1% of the patients. In-hospital mortality was calculated as 12.8%. Age-adjusted and multivariate logistic regression analysis (p:0.005, odds ratio:0.974, CI:0.956-0.992) showed that baseline eGFR was independently associated with mortality. Additionally, age-adjusted Cox regression analysis revealed a higher mortality rate in patients with an eGFR under 60 mL/min/1.73m2.ConclusionsOn admission eGFR seems to be a prognostic marker for mortality in patients with COVID-19; We recommend to determine eGFR in all patients on admission and use it as an additional tool for risk stratification. Close follow-up should be warranted in patients with reduced eGFR.

Published
2020

37. Mortality analysis of COVID-19 infection in chronic kidney disease, haemodialysis and renal transplant patients compared with patients without kidney disease: a nationwide analysis from Turkey

Author

Ozturk, Savas, primary, Turgutalp, Kenan, additional, Arici, Mustafa, additional, Odabas, Ali Riza, additional, Altiparmak, Mehmet Riza, additional, Aydin, Zeki, additional, Cebeci, Egemen, additional, Basturk, Taner, additional, Soypacaci, Zeki, additional, Sahin, Garip, additional, Elif Ozler, Tuba, additional, Kara, Ekrem, additional, Dheir, Hamad, additional, Eren, Necmi, additional, Suleymanlar, Gultekin, additional, Islam, Mahmud, additional, Ogutmen, Melike Betul, additional, Sengul, Erkan, additional, Ayar, Yavuz, additional, Dolarslan, Murside Esra, additional, Bakirdogen, Serkan, additional, Safak, Seda, additional, Gungor, Ozkan, additional, Sahin, Idris, additional, Mentese, Ilay Berke, additional, Merhametsiz, Ozgur, additional, Oguz, Ebru Gok, additional, Genek, Dilek Gibyeli, additional, Alpay, Nadir, additional, Aktas, Nimet, additional, Duranay, Murat, additional, Alagoz, Selma, additional, Colak, Hulya, additional, Adibelli, Zelal, additional, Pembegul, Irem, additional, Hur, Ender, additional, Azak, Alper, additional, Taymez, Dilek Guven, additional, Tatar, Erhan, additional, Kazancioglu, Rumeyza, additional, Oruc, Aysegul, additional, Yuksel, Enver, additional, Onan, Engin, additional, Turkmen, Kultigin, additional, Hasbal, Nuri Baris, additional, Gurel, Ali, additional, Yelken, Berna, additional, Sahutoglu, Tuncay, additional, Gok, Mahmut, additional, Seyahi, Nurhan, additional, Sevinc, Mustafa, additional, Ozkurt, Sultan, additional, Sipahi, Savas, additional, Bek, Sibel Gokcay, additional, Bora, Feyza, additional, Demirelli, Bulent, additional, Oto, Ozgur Akin, additional, Altunoren, Orcun, additional, Tuglular, Serhan Zubeyde, additional, Demir, Mehmet Emin, additional, Ayli, Mehmet Deniz, additional, Huddam, Bulent, additional, Tanrisev, Mehmet, additional, Bozaci, Ilter, additional, Gursu, Meltem, additional, Bakar, Betul, additional, Tokgoz, Bulent, additional, Tonbul, Halil Zeki, additional, Yildiz, Alaattin, additional, Sezer, Siren, additional, and Ates, Kenan, additional

Published
2020
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42. Kidney function on admission predicts in-hospital mortality in COVID-19

Author

Trabulus, Sinan, primary, Karaca, Cebrail, additional, Balkan, Ilker Inanc, additional, Dincer, Mevlut Tamer, additional, Murt, Ahmet, additional, Ozcan, Seyda Gul, additional, Karaali, Rıdvan, additional, Mete, Bilgul, additional, Bakir, Alev, additional, Kuskucu, Mert Ahmet, additional, Altiparmak, Mehmet Riza, additional, Tabak, Fehmi, additional, and Seyahi, Nurhan, additional

Published
2020
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45. Cost of renal replacement therapy in Turkey

Author

EREK, EKREM, SEVER, MEHMET ŞÜKRÜ, AKOGLU, EMEL, SARIYAR, MUZAFFER, BOZFAKIOGLU, SEMRA, APAYDIN, SUHEYLA, ATAMAN, REZZAN, SARSMAZ, NEDIM, ALTIPARMAK, MEHMET RIZA, SEYAHI, NURHAN, and SERDENGEÇTI, KAMIL

Published
2004

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