1. A case report of allergic bronchopulmonary mycosis caused by Alternaria alternata in colonization of Aspergillus.
- Author
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Jo MJ, Yeo Y, Min KW, Chung SJ, Park TS, Lee H, Park DW, Moon JY, Sohn JW, Kim SH, Yoon HJ, and Kim TH
- Subjects
- Humans, Female, Middle Aged, Immunoglobulin E blood, Immunoglobulin E immunology, Alternariosis diagnosis, Alternariosis immunology, Tomography, X-Ray Computed, Skin Tests, Alternaria immunology, Aspergillus immunology, Aspergillosis, Allergic Bronchopulmonary diagnosis, Aspergillosis, Allergic Bronchopulmonary drug therapy, Aspergillosis, Allergic Bronchopulmonary immunology, Aspergillosis, Allergic Bronchopulmonary microbiology
- Abstract
Background: Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease caused by a complex hypersensitivity reaction to colonization of the airways with various fungi. ABPA caused by Alternaria alternata, other than Aspergillus spp., is named Allergic bronchopulmonary mycosis (ABPM)., Objective: To describe the first case of ABPM caused by Alternaria alternata in East Asia., Methods: Case report., Results: A 58-year-old female visited our hospital due to an abnormal chest x-ray, following chest computed tomography (CT) revealed consolidation in the left lower lobe. On laboratory finding, eosinophil count and total IgE level were high. The skin prick test and specific IgE for Alternaria alternata were positive. After diagnosis of ABPM, the patient was treated with prednisolone without antifungal agents, and her chest image was much improved., Conclusions: Aspergillus is most common etiology of allergic pulmonary disease, however, Alternaria should be considered even though positive culture of Aspergillus spp.
- Published
- 2024
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