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378 results on '"Altekruse, Sean F."'

1. Pathology Laboratory Policies and Procedures for Releasing Diagnostic Tissue for Cancer Research

Author

Yuan, Yao, Van Dyke, Alison L, Petkov, Valentina I, Hussey, Sarah, Moravec, Radim, Altekruse, Sean F, Sandoval, Mayra, Cress, Rosemary D, Mueller, Lloyd M, Mogi, Alan, Hernandez, Brenda Y, Selk, Freda R, Lynch, Charles F, Tucker, Thomas C, Lynch, Mary Anne, Lefante, Christina, Wu, Xiao-Cheng, Sweeney, Carol, Doherty, Jennifer A, and Penberthy, Lynne S

Subjects
Rare Diseases, Cancer, Formaldehyde, Humans, Laboratories, Neoplasms, Paraffin Embedding, Pathology, Policy, Research, SEER Program, Tissue Fixation, Clinical Sciences
Abstract

Context.—The Surveillance, Epidemiology, and End Results (SEER) cancer registry program is currently evaluating the use of archival, diagnostic, formalin-fixed, paraffin-embedded (FFPE) tissue obtained through SEER cancer registries, functioning as honest brokers for deidentified tissue and associated data. To determine the feasibility of this potential program, laboratory policies for sharing tissue for research needed to be assessed.Objective.—To understand the willingness of pathology laboratories to share archival diagnostic tissue for cancer research and related policies.Design.—Seven SEER registries administered a 27-item questionnaire to pathology laboratories within their respective registry catchment areas. Only laboratories that processed diagnostic FFPE specimens and completed the questionnaire were included in the analysis.Results.—Of the 153 responding laboratories, 127 (83%) responded that they process FFPE specimens. Most (n = 88; 69%) were willing to share tissue specimens for research, which was not associated with the number of blocks processed per year by the laboratories. Most laboratories retained the specimens for at least 10 years. Institutional regulatory policies on sharing deidentified tissue varied considerably, ranging from requiring a full Institutional Review Board review to considering such use exempt from Institutional Review Board review, and 43% (55 of 127) of the laboratories did not know their terms for sharing tissue for research.Conclusions.—This project indicated a general willingness of pathology laboratories to participate in research by sharing FFPE tissue. Given the variability of research policies across laboratories, it is critical for each SEER registry to work with laboratories in their catchment area to understand such policies and state legislation regulating tissue retention and guardianship.

Published
2021

2. Associations between QT interval subcomponents, HIV serostatus, and inflammation

Author

Wu, Katherine C, Bhondoekhan, Fiona, Haberlen, Sabina A, Ashikaga, Hiroshi, Brown, Todd T, Budoff, Matthew J, D'Souza, Gypsyamber, Magnani, Jared W, Kingsley, Lawrence A, Palella, Frank J, Margolick, Joseph B, Martínez‐Maza, Otoniel, Altekruse, Sean F, Soliman, Elsayed Z, and Post, Wendy S

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, HIV/AIDS, Prevention, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Good Health and Well Being, Adult, Aged, Biomarkers, Electrocardiography, HIV Infections, Humans, Inflammation, Long QT Syndrome, Longitudinal Studies, Male, Middle Aged, Prospective Studies, Risk Factors, arrhythmias, electrocardiography, HIV, inflammation, QT interval, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BackgroundThe total QT interval comprises both ventricular depolarization and repolarization currents. Understanding how HIV serostatus and other risk factors influence specific QT interval subcomponents could improve our mechanistic understanding of arrhythmias.MethodsTwelve-lead electrocardiograms (ECGs) were acquired in 774 HIV-infected (HIV+) and 652 HIV-uninfected (HIV-) men from the Multicenter AIDS Cohort Study. Individual QT subcomponent intervals were analyzed: R-onset to R-peak, R-peak to R-end, JT segment, T-onset to T-peak, and T-peak to T-end. Using multivariable linear regressions, we investigated associations between HIV serostatus and covariates, including serum concentrations of inflammatory biomarkers such as interleukin-6 (IL-6), and each QT subcomponent.ResultsAfter adjustment for demographics and risk factors, HIV+ versus HIV- men differed only in repolarization phase durations with longer T-onset to T-peak by 2.3 ms (95% CI 0-4.5, p

Published
2020

3. NCI SEER-Linked Virtual Tissue Repository Pilot.

Author

Sanchez, Pamela, Dyke, Alison L Van, Petkov, Valentina I, Yuan, Yao, Bonds, Sarah, Valenzuela, Connor, Tuan, Alyssa W, Moravec, Radim, Altekruse, Sean F, Singhi, Aatur D, Serdy, Kate M, Wu, Yun, Cress, Rosemary D, Doherty, Jennifer A, Mueller, Lloyd, Hernandez, Brenda Y, Lynch, Charles F, Tucker, Thomas C, Wu, Xiao-Cheng, and Matrisian, Lynn

Published
2024
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4. Cancer burden attributable to cigarette smoking among HIV-infected people in North America

Author

Altekruse, Sean F, Shiels, Meredith S, Modur, Sharada P, Land, Stephanie R, Crothers, Kristina A, Kitahata, Mari M, Thorne, Jennifer E, Mathews, William C, Fernández-Santos, Diana M, Mayor, Angel M, Gill, John M, Horberg, Michael A, Brooks, John T, Moore, Richard D, Silverberg, Michael J, Althoff, Keri N, and Engels, Eric A

Subjects
Health Services and Systems, Biomedical and Clinical Sciences, Health Sciences, Sexually Transmitted Infections, Lung Cancer, Tobacco, Behavioral and Social Science, HIV/AIDS, Lung, Cancer, Infectious Diseases, Substance Misuse, Tobacco Smoke and Health, Prevention, Respiratory, Adolescent, Adult, Aged, Aged, 80 and over, Cigarette Smoking, Female, Follow-Up Studies, HIV Infections, Humans, Incidence, Male, Middle Aged, Neoplasms, North America, Prevalence, Risk Factors, Young Adult, attributable risk, cancer, HIV, smoking, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Virology, Biomedical and clinical sciences, Health sciences
Abstract

ObjectiveWith combination-antiretroviral therapy, HIV-infected individuals live longer with an elevated burden of cancer. Given the high prevalence of smoking among HIV-infected populations, we examined the risk of incident cancers attributable to ever smoking cigarettes.DesignObservational cohort of HIV-infected participants with 270 136 person-years of follow-up in the North American AIDS Cohort Collaboration on Research and Design consortium. Among 52 441 participants, 2306 were diagnosed with cancer during 2000-2015.Main outcome measuresEstimated hazard ratios and population-attributable fractions (PAF) associated with ever cigarette smoking for all cancers combined, smoking-related cancers, and cancers that were not attributed to smoking.ResultsPeople with cancer were more frequently ever smokers (79%) compared with people without cancer (73%). Adjusting for demographic and clinical factors, cigarette smoking was associated with increased risk of cancer overall [hazard ratios = 1.33 (95% confidence interval: 1.18-1.49)]; smoking-related cancers [hazard ratios = 2.31 (1.80-2.98)]; lung cancer [hazard ratios = 17.80 (5.60-56.63)]; but not nonsmoking-related cancers [hazard ratios = 1.12 (0.98-1.28)]. Adjusted PAFs associated with ever cigarette smoking were as follows: all cancers combined, PAF = 19% (95% confidence interval: 13-25%); smoking-related cancers, PAF = 50% (39-59%); lung cancer, PAF = 94% (82-98%); and nonsmoking-related cancers, PAF = 9% (1-16%).ConclusionAmong HIV-infected persons, approximately one-fifth of all incident cancer, including half of smoking-related cancer, and 94% of lung cancer diagnoses could potentially be prevented by eliminating cigarette smoking. Cigarette smoking could contribute to some cancers that were classified as nonsmoking-related cancers in this report. Enhanced smoking cessation efforts targeted to HIV-infected individuals are needed.

Published
2018

10. Supplementary Figure 3 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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11. Data from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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12. Supplementary Figure Legends from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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13. Supplementary Table 1 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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14. Supplementary Figure 2 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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15. Supplementary Figure 6 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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16. Supplementary Figure 4 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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17. Supplementary Figure 1 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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18. Supplementary Figure 5 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

Author

Jia, Jinping, primary, Bosley, Allen D., primary, Thompson, Abbey, primary, Hoskins, Jason W., primary, Cheuk, Adam, primary, Collins, Irene, primary, Parikh, Hemang, primary, Xiao, Zhen, primary, Ylaya, Kris, primary, Dzyadyk, Marta, primary, Cozen, Wendy, primary, Hernandez, Brenda Y., primary, Lynch, Charles F., primary, Loncarek, Jadranka, primary, Altekruse, Sean F., primary, Zhang, Lizhi, primary, Westlake, Christopher J., primary, Factor, Valentina M., primary, Thorgeirsson, Snorri, primary, Bamlet, William R., primary, Hewitt, Stephen M., primary, Petersen, Gloria M., primary, Andresson, Thorkell, primary, and Amundadottir, Laufey T., primary

Published
2023
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46. Salmonella enteritidis in broiler chickens, United States, 2000-2005

Author

Altekruse, Sean F., Bauer, Nathan, Chanlongbutra, Amy, DeSagun, Robert, Naugle, Alecia, Schlosser, Wayne, Umholtz, Robert, and White, Patricia

Subjects
Salmonella enteritidis -- Research, Salmonella enteritidis -- Health aspects, Broilers (Poultry) -- Diseases
Abstract

US Department of Agriculture Food Safety and Inspection Service (FSIS) data on Salmonella enterica serotype Enteritidis in broiler chicken carcass rinses collected from 2000 through 2005 showed the annual number [...]

Published
2006

47. Salmonella Enteritidis infections, United States, 1985-1999

Author

Patrick, Mary E., Adcock, Penny M., Gomez, Thomas M., Altekruse, Sean F., Holland, Ben H., Tauxe, Robert V., and Swerdlow, David L.

Subjects
Salmonella enteritidis
Abstract

Salmonella enterica serotype Enteritidis emerged as an important illness during the 1980s. Investigations showed that consumption of undercooked eggs was the major risk factor for disease, and a variety of [...]

Published
2004

50. Pathology Laboratory Policies and Procedures for Releasing Diagnostic Tissue for Cancer Research

Author

Yuan, Yao, primary, Van Dyke, Alison L., additional, Petkov, Valentina I., additional, Hussey, Sarah, additional, Moravec, Radim, additional, Altekruse, Sean F., additional, Sandoval, Mayra, additional, Cress, Rosemary D., additional, Mueller, Lloyd M., additional, Mogi, Alan, additional, Hernandez, Brenda Y., additional, Selk, Freda R., additional, Lynch, Charles F., additional, Tucker, Thomas C., additional, Lynch, Mary Anne, additional, Lefante, Christina, additional, Wu, Xiao-Cheng, additional, Sweeney, Carol, additional, Doherty, Jennifer A., additional, and Penberthy, Lynne S., additional

Published
2020
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