41 results on '"Altın, Remzi"'
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2. Examination of lung toxicity, oxidant/antioxidant status and effect of erdosteine in rats kept in coal mine ambience
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Armutcu, Ferah, Gun, Banu Dogan, Altin, Remzi, and Gurel, Ahmet
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- 2007
- Full Text
- View/download PDF
3. Color Doppler evaluation of the ocular arterial flow changes in chronic obstructive pulmonary disease
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Ozer, Tulay, Altin, Remzi, Ugurbas, Suat Hayri, Ozer, Yetkin, Mahmutyazicioglu, Kamran, and Kart, Levent
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- 2006
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4. Antioxidant response at early stages and low grades of simple coal worker's pneumoconiosis diagnosed by high resolution computed tomography
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Altin, Remzi, Armutcu, Ferah, Kart, Levent, Gurel, Ahmet, Savranlar, Ahmet, and Özdemir, Hüseyin
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- 2004
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5. Presence and HRCT quantification of bronchiectasis in coal workers
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Altin, Remzi, Savranlar, Ahmet, Kart, Levent, Mahmutyazicioglu, Kamran, Ozdemir, Huseyin, Akdag, Beyza, and Gundogdu, Sadi
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- 2004
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6. Comparison of chest radiography and high-resolution computed tomography findings in early and low-grade coal worker’s pneumoconiosis
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Savranlar, Ahmet, Altın, Remzi, Mahmutyazıcıoğlu, Kamran, Özdemir, Hüseyin, Kart, Levent, Özer, Tülay, and Gündoğdu, Sadi
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- 2004
- Full Text
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7. Antituberculosis drug resistance patterns in two regions of Turkey: a retrospective analysis
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Oymak Sema F, Gulmez Inci, Tor Meltem, Altın Remzi, Kart Levent, Atmaca Hulusi M, and Erdem Funda
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Tuberculosis ,Drug resistance ,Epidemiology ,Turkey ,Therapeutics. Pharmacology ,RM1-950 ,Infectious and parasitic diseases ,RC109-216 ,Microbiology ,QR1-502 - Abstract
Abstract Backround The emergence of Mycobacterium tuberculosis strains resistant to antituberculosis agents has recently received increased attention owing largely to the dramatic outbreaks of multi drug resistance tuberculosis (MDR-TB). Methods Patients residing in Zonguldak and Kayseri provinces of Turkey with, pulmonary tuberculosis diagnosed between 1972 and 1999 were retrospectively identified. Drug susceptibility tests had been performed for isoniazid (INH), rifampin (RIF), streptomycin (SM), ethambutol (EMB) and thiacetasone (TH) after isolation by using the resistance proportion method. Results Total 3718 patients were retrospectively studied. In 1972–1981, resistance rates for to SM and INH were found to be 14.8% and 9.8% respectively (n: 2172). In 1982–1991 period, resistance rates for INH, SM, RIF, EMB and TH were 14.2%, 14.4%, 10.5%, 2.7% and 2.9% (n: 683), while in 1992–1999 period 14.4%, 21.1%, 10.6%, 2.4% and 3.7% respectively (n: 863). Resistance rates were highest for SM and INH in three periods. MDR-TB patients constituted 7.3% and 6.6% of 1982–1991 and 1992–1999 periods (p > 0.05). Conclusion This study demonstrates the importance of resistance rates for TB. Continued surveillance and immediate therapeutic decisions should be undertaken in order to prevent the dissemination of such resistant strains.
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- 2002
- Full Text
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8. Leptin levels in children with obstructive sleep apnea syndrome
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Söğüt, Ayhan, Açıkgöz, Şerefden, Uzun, Lokman, Uğur, Mehmet Birol, Altın, Remzi, Dağlı, Elif, Kadıtıs, Athanasios, and Zonguldak Bülent Ecevit Üniversitesi
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Solunum Sistemi ,Boğaz ,Kulak ,Burun - Abstract
Obstrüktif uyku apne sendromlu çocuklarda leptin seviyeleriGiriş: Bu çalışmanın amacı çocuklarda leptin seviyeleri üzerinde obstrüktif uyku apne sendromu (OUAS)'nun etkisini değerlendirmektir.Hastalar ve Metod: Habitual horlaması olan çocuklara polisomnografi yapıldı. Uyku çalışmasını takip eden sabah 08.00-09.00 saatleri arasında açlık venöz kan alındı. Apne-hipopne indeksi >= 5/saat olan çocuklar orta-ciddi OUAS, < 5/saat olan çocuklar hafif OUAS/primer horlama grubuna alındı.Bulgular: Çalışmaya 47 çocuk (%51 erkek ve %49 kız; yaş ortalaması 7.8 ± 2.6 yıl) alındı. Yirmi yedi çocuk orta-ciddi OUAS, hafif OUAS/primer horlama grubunda yer aldı. İki grup arasında yaş, cinsiyet ve vücut kitle indeksi açısından anlamlı fark yoktu (p> 0.05). Log serum leptin seviyeleri gruplar arasında farklı değildi (p= 0.749). Çalışma grubunun tümünde log leptin seviyeleri BMI z skoru ile pozitif korelasyon gösterdi (p= 0.001; r= 0.499), fakat log leptin seviyeleri apne-hipopne indeksi, ortalama ve en düşük oksijen satürasyonu ile korelasyon göstermedi.Sonuç: Habitual horlaması olan çocuklarda serum leptin seviyeleri yağ dokusundan etkilenmektedir fakat OUAS şiddetinden etkilenmemektedir., Introduction: The aim of this study is to assess the effect of obstructive sleep apnea syndrome (OSAS) severity on leptin levels in children. Patients and Methods: Children with habitual snoring underwent overnight polysomnography. Fasting venous blood samples were obtained between 8 AM and 9 AM, following the night of the sleep study. Children with an apnea-hypopnea index of >= 5/h were included in the moderate-to-severe OSAS group while those with an apnea-hypopnea index of < 5/h formed the mild OSAS/primary snoring group.Results: 47 children (51% male and 49% female; mean age 7.8 ± 2.6 years) were recruited. Twenty seven participants were diagnosed with moderate-to-severe OSAS, and twenty children who had AHI < 5 were included in the mild OSAS/primary snoring. The two groups did not differ regarding age, gender and body mass index z score (p> 0.05). Furthermore there were no differences in log serum leptin levels (p= 0.749). Log serum leptin levels correlated with the BMI z score in the whole study group (p= 0.001; r= 0.499) but they were not associated with apnea-hypopnea index, mean and lowest oxygen saturation during sleep.Conclusion: Serum leptin levels are affected by adiposity but not by OSAS severity among children with habitual snoring.
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- 2016
9. THE DIAGNOSTIC EFFECTIVENESS OF THREE CARDINAL SYMPTOMS IN SLEEP APNEA SYNDROME WHEN ASKED ROUTINELY IN OUT-PATIENT VISITS
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Aktunç, Erol, Altın, Remzi, DEMİRCAN, Nejat, TOR, Meltem, UNALACAK, Murat, KART, Levent, and MEDİCİNE, Pulmonary
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Sleep apnea,primary care,diagnosis,screening,referral - Abstract
Aim: In this study we investigated the increase in patient referral rates and diagnosis of obstructive sleep apnea syndrome (OSAS) by asking three cardinal symptoms. Methods: Patients who applied with different complaints to the family practice out-patient clinic between 04.01.2003 and 10.31.2003 (n=413) consisted the study group and they, along with their spouses, were asked about three cardinal symptoms of OSAS. Control group consisted 451 age and sex matched out-patients who had applied before the initiation of the study. Symptom positive patients were referred to an ear-nose-throat specialist and a sleep disorders specialist. Polysomnography was performed if indicated. Student-t test and chi-square test were used as appropriate. Results: There were no significant differences between groups about age, sex and body mass index (BMI) values. Patients diagnosed as OSAS were predominantly males. The mean BMI values for each group were classified as overweight. The rate of referral in control group was significantly lower than the study group. Out of the 413 patients three (%0.7) were diagnosed as OSAS, five (%1.2) were diagnosed as simple snoring. One of the three patients diagnosed as OSAS was female and the other two were male. Conclusions: It is our conclusion that all patients in primary care settings should be screened for cardinal symptoms of OSAS in order to prevent further complications and improve their quality of life. We started routine screening of all patients for OSAS by using three cardinal symptoms in our primary care out-patient clinic
- Published
- 2015
10. Tekirdağ’da Tüberkülozun Yıllar İçindeki Değişimi
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Güneş, Hayati, Altın, Remzi, Mutlu, Levent Cem, Doğan, Mustafa, Oran, Mustafa, Işık, Salman, Salt, Gürdal, Kaya, Ayşe Demet, and Topçu, Birol
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antitüberküloz ajanlar ,Tüberküloz ,antibiyotik direnci ,antibiotic resistance ,multidrug resistance ,Incidence ,Tuberculosis ,insidans ,çoklu ilaç direnci ,antitubercular agents - Abstract
Amaç Dünya Sağlık Örgütü tarafından tüm dünyada hesaplanan tüberküloz (TB) insidansı 100.000'de 128'dir. TB kontrolünün ana prensipleri erken tanı ve tedavi, bunu takiben de hastaların direkt gözlemsel tedavisidir. Bu çalışmanın amacı, 2007-2011 yılları arasında Tekirdağ’da tüberküloz verilerindeki değişimin analizini yapmaktı. Materyal ve Metod Tekirdağ il sınırları içinde bulunan Tekirdağ ve Çorlu Verem savaş dispanserlerinden elde edilen veriler birer yıllık kategorilere ayrıldı. Hastalar, yaş gruplarına göre 0-14, 15-24, 25-44, 45-64, 65 ve Üzeri olmak Üzere 5 gruba ayrıldı ve vaka bildirim oranları tüm gruplarda analiz edildi. Hastalar, tutulan organa göre 2 gruba ayrıldı: Pulmoner (smear/kültür pozitif =PSP ve smear/kültür negatif/bilinmeyen =PSB/N) ve ekstrapulmoner. Kültürde üremiş ve dirençli olduğundan şüphelenilen M. Tuberculosis suşlarına major ilaçlar olan izoniazid (INH), rifampisin, etambutol ve streptomisine karşı duyarlılık testi uygulandı. INH ve rifampisine dirençli suşlar çoklu ilaca dirençli tüberküloz olarak kabul edildi (ÇİD-TB). Bulgular Toplam 162.291 hasta muayene edildi ve bunlardan 1311 (%0,8)’i TB hastası olarak değerlendirildi. Vaka bildirim oranlarının yıllara gore dağılımı 2007 ile 2011 arasında sırasıyla %44,6, %34,6, %33,4 ve %28,6 idi. Pulmoner ve ekstrapulmoner TB oranları sırasıyla %74,5 (%46 PSP ve %28,5 PSN/B) ve %25,5 idi. Ekstrapulmoner tüberküloz oranları erkekler ve kadınlarda sırasıyla %42,3 ve %17,6 idi. INH, rifampisin, etambutol ve streptomisine direnöoranları sırasıyla %21,6, %8,8, %1,6 ve %6,4 idi. ÇİD-TB oranı %6,4 olarak tespit edildi. Sonuç Doğrudan gözetimli tedavinin sistematik uygulanması tüberküloz insidansının düşmesinde önemli rol oynar. Bölgemizde tüberküloz oranları türkiye ortalamasının üzerinde olduğundan tarama ve takip prosedürleri daha sıkı ve düzenli olarak uygulanmalıdır. Aim The incidence rate of tuberculosis (TB) is estimated by the World Health Organization as 128/100.000 worldwide. The main principles of TB control are early case detection and diagnosis, followed by directly observed treatment of patients. The aim of this study was to analyse the dynamics of TB between 2007 and 2011 in Tekirdağ. Material and Methods Data were obtained from TB dispensaries and separated into oneyear categories. Case notification rates were analysed by different age groups (0–14, 15–24, 25–44, 45–64, 65 and above). The patients were divided into two groups according to involved organs: pulmonary (smear/culture positive=PSP and smear/culture negative/unknown=PSN/U) and extrapulmonary. Antibiotic susceptibility tests to major antituberculosis drugs were performed on M. tuberculosis strains that were grown in culture and suspected of being resistant. Resistance to both INH and rifampicin were accepted as multiple drug resistance tuberculosis (MDR-TB). Results A total of 162.291 patients were examined, and out of this population, 1311 (0.8%) tuberculosis patients were evaluated. The distribution of case notification rates by year were 44.6%, 34.6%, 33.4%, 28.6%, and 27.6%from 2007 to 2011, respectively. Pulmonary and extrapulmonary TB rates were 74.5%(46.0%PSP and 28.5%PSN/U) and 25.5%, respectively. Extrapulmonary TB rates were 42.3% and 17.6% in men and women, respectively. Resistance rates against INH, rifampicin, ethambutol, and streptomycin were 21.6%, 8.8%, 1.6%, and 6.4%, respectively. The MDR-TB rate was 6.4%. Conclusion Systematic implementation of directly observed treatment programs plays an important role in decreasing TB incidence. Because the TB rates in our region are above the average for Turkey, screening and follow-up procedures must be conducted more stringently and regularly.
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- 2015
11. Diagnostic value of oropharyngeal examination findings in differentiating pediatric obstructive sleep apnea syndrome from habitual snoring
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Söğüt, Ayhan, Uzun, Lokman, Altın, Remzi, Uğur, Mehmet Birol, and Zonguldak Bülent Ecevit Üniversitesi
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stomatognathic system ,Sleep Apnea,Obstructive,Snoring,Child,Diagnosis,Differential ,Uyku apne,tıkayıcı,Horlama,Çocuk,Tanı,ayırıcı ,Cerrahi ,nervous system diseases ,respiratory tract diseases - Abstract
Objective: Obstructive sleep apnea syndrome (OSAS) in children is a serious disease, estimated to occur in approximately 2% pf children and is characterized by repeated episodes of complete or partial upper airway obstruction during sleep. Habitual snoring (HS) is a common symptom seen in %7-Q of children. Although there is no hypercapnia and hypoxemia in HS, presence of examination findings suggestive of OSAS in HS makes the clinical differentiation of these two conditions a challenging one. In this study we evaluated children with HS and OSAS and assessed the diagnostic value of the findings of oropharyngeal examination in the clinical differentiation of these two disorders. Material and Method: 74 children with every night snoring symptom were included in the study. Detailed history with regard to OSAS symptoms was obtained and physical examinations was performed for each child. Children were classified in either OSAS orHS group according to polysomnography results. Children with more than two spells of apnea or hypopnea per hour of sleep were classified as OSAS. Palatine tonsil and adenoid vegetation sizes and mallampati scores were compared between the two groups for each stage by using chi-square test. Results: There were 17 and 57 children in the HS and OSAS groups, respectively. There wasn't any statistically significant difference between the two groups in terms of adenotonsillary hypertrophy and higher mallampati scores (p>0.05). Stage 1 palatine tonsil size was more frequent in HS group than OSAS group and the difference was close to statistical significance (p-0.07). Conclusion: According to the findings of this study only stage 1 palatine tonsil size was more frequent in HS group than OSAS group with a difference close to statistical significance.- Oropharyngeal . examination findings are not sufficient to distinguish children with HS from those with OSAS and the findings are similar in two groups., Amaç: Çocukluk çağı tıkayıcı uyku apnesi sendmmu (TUAS) çocukların yaklaşık % 2'sinde görülen ciddi bir hastalık olup uyku sırasında tekrarlayan kısmi veya tam üst hava yolu tıkanıklığı epizodlan ile karakterizedir. Habituel horlama (HH) çocukların % 7-9'unda görülen sık bir semptomdur. HH'h çocuklarda hipoksemi ve hiperkapni bulunmamasına rağmen, TUAS varlığına işaret eden muayene bulgularının bulunması bu iki durumun klinik ayrımını güçleştirmektedir. Bu çalışmada, habituel horlama ve TUAS'u olan çocukları inceleyerek, bu iki bozukluğun klinik ayrımında orofarengeal muayene bulgularının tanısal değerini araştırdık. Gereç ve Yöntem: Bu çalışmaya her gece horlama şikayeti olan 74 çocuk dahil edildi. Her çocuğun TUAS ile ilişkili semptomlar açısından ayrıntılı anamnezi alındı ve fizik muayenesi yapıldı. Polisomnogra.fi sonuçlarına göre çocuklar TUAS ve habituel horlama gruplarından birine dahil edildi. Uykuda saat başı iki veya daha fazla apne veya hipopne atağı olan çocuklar TUAS olarak sınıflandırıldı. Palatin tonsil, adenoid büyüklüğü ve mallampati skorları her bir evre için iki grup arasında ki-kare testi ile karşılaştırıldı. Bulgular: Olguların 17'si HH ve 57'si TUAS'lı idi. Adenotonsil hipertrofili veya mallampati evresi yüksek olan hastaların TUAS ve HH grupları arasındaki dağılımı açısından istatistiksel olarak anlamlı farklılık saptanmadı (p>0.05). Evre 1 palatin tonsil'büyüklüğü HH grupta TUAS'lı gruba göre sınırda anlamlı olarak daha yüksek oranda bulundu (p = 0.07) Sonuç: Bu çalışmada elde edilen bulgulara göre,sadece evre 1 palatin tonsil büyüklüğü HH grupta TUAS'lı gruba göre sınırda anlamlı olarak daha . yüksele oranda görülmekte olup, orofarengeal muayene bulguları İVAS ve HH'nm kesin ayrımında yeterli olmamakta, her iki grupta da benzer muayene bulguları gözlenmektedir.
- Published
- 2014
12. Tekirdağ İlinde 2007-2011 Yılları Arası Tüberkülozun Mevsimselliği
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Mutlu, Levent Cem, Altın, Remzi, Güneş, Hayati, Doğan, Mustafa, Oran, Mustafa, Işık, Salman, Salt, Gürdal, Kaya, Ayşe Demet, and Topçu, Birol
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Tüberküloz ,seasonality ,Incidence ,Tuberculosis ,insidans ,mevsimsellik - Abstract
Amaç Pek çok solunumsal enfeksiyonun mevsimsel değişkenlik gösterdiği bilinmektedir. Bununla birlikte pek çok çalışmada, diğer solunumsal enfeksiyonlardan farklı olarak tüberküloz tanısı alan hasta sayısı yaz aylarında artış göstermektedir ve altta yatan mekanizma tam olarak açıklanamamıştır. Çalışmamızda, Tekirdağ ilinde tüberküloz tanısının mevsimsellik gösterip göstermediğinin araştırılması hedeflenmiştir. Materyal ve Metot Bu amaçla Tekirdağ Verem Savaş Dispanserlerinde kayıtlı olan hastaların dosyaları geriye dönük olarak taranarak, Ocak 2007 ile Aralık 2011 tarihleri arasında 1311 hastaya tüberküloz teşhisi konulmuş olduğu tespit edilmiştir. Bulgular Tüberküloz tanısının % 28,4 oranıyla en sık yaz aylarında konulmuş olduğu saptanmıştır. Sonuç Sonuç olarak farklı ülkelerde yapılan çalışmalara benzer şekilde Tekirdağ’da da tüberkülozun mevsimsellik gösterdiği tespit edilmiştir. Hastalığın daha iyi kontrolünü sağlamada altta yatan mekanizmaları açıklayacak prospektif çalışmalara ihtiyaç olduğu kanısına varılmıştır. Aim It is well known that the incidence of many respiratory infections shows seasonal variability. Unlike other respiratory infections, in many studies tuberculosis (TB) diagnoses increase in summer and the mechanism underlying this fluctuation remains unknown. We aimed to examine whether TB has an annual seasonal pattern in Tekirdağ. Materials and Methods Data were obtained from TB dispensaries in Tekirdağ retrospectively. There were 1311 cases of TB notified between January 2007 and December 2011. TB notifications show a seasonal pattern, with a peak in spring and summer, which is present in both pulmonary and extra pulmonary tuberculosis. Results TB notification was found highest in summer with the value of 28,4 %. Conclusion TB incidence in Tekirdağ showed seasonality like previous studies held in different countries. There is a need for large longitudinal studies to clarify the underlying mechanisms that may provide a better disease control.
- Published
- 2014
13. The benefit of expiratory-phase quantitative CT densitometry in the early diagnosis of chronic obstructive pulmonary disease
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Beşir, Fahri Halit, Mahmutyazıcıoğlu, Kamran, Aydın, Leyla, Altın, Remzi, Asil, Kıyasettin, and Gündoğdu, Sadi
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expiratory phase ,chronic obstructive pulmonary disease (COPD) ,CT densitometry ,respiratory tract diseases ,early diagnosis - Abstract
WOS: 000316061000002 PubMed: 22261851 PURPOSE We aimed to compare the inspiratory and expiratory quantitative computed tomography (CT) densitometric data of healthy volunteers, individuals with chronic obstructive pulmonary disease (COPD) risk, and COPD patients to aid in the early diagnosis of COPD. MATERIALS AND METHODS Of the study patients, 14 were healthy volunteers (Group I), 12 were patients at risk for COPD (Group II), and 13 were COPD patients (Group III). The high-resolution CT was performed at three levels (the upper, middle, and lower parts of the lungs). All images were evaluated with a specific program for the segmentation of pulmonary parenchyma. The mean lung density (MLD) was measured, and the emphysema index (EI) was calculated using this program. RESULTS Both MLD values and calculated EI ratios showed significant differences between Groups I and III, and Groups II and III in both expiratory and inspiratory phases (P < 0.05). However, in the comparison of healthy volunteers and patients at risk for COPD (Group I and II), only expiratory-phase MLD values showed statistically significant difference (P < 0.001). CONCLUSION In patients at risk for COPD, expiratory-phase MLD measurements can be used as an early diagnostic method.
- Published
- 2012
14. Lower respiratory tract infection rates associated with invasive and noninvasive mechanical ventilation in patients with respiratory failure
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AKKOYUNLU, YASEMİN, AKKOYUNLU, MUHAMMED EMİN, Erboy, Fatma, Altın, Remzi, ASLAN, TURAN, and AKKOYUNLU, YASEMİN
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AKKOYUNLU Y., AKKOYUNLU M. E. , Erboy F., Altın R., ASLAN T., -Lower respiratory tract infection rates associated with invasive and noninvasive mechanical ventilation in patients with respiratory failure-, The 4th Eurasia Congress of Infectious Diseases, Saray Bosna, Bosna-Hersek, 01 June 2011, ss.3 - Published
- 2011
15. Tansiyon pnömotoraksı taklit eden dev bül
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Gökçe, Mertol, Saydam, Özkan, Altın, Remzi, Kart, Levent, and Zonguldak Bülent Ecevit Üniversitesi
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Solunum Sistemi ,Boğaz ,Kulak ,Burun - Abstract
Göğüs grafisinde, tansiyon pnömotoraksı, bir hemitoraksta geniş radyolüsenite ve mediastinal yapıları karşı tarafa itmiş olarak izleriz. Dev bül de geniş radyolüsen görünümü ve mediastinal şift oluşturarak tansiyon pnömotoraksı taklit edebilir. Sunduğumuz olgu dev akciğer bülü olan 35 yaşında bir kadındır. Dev bül acil serviste tansiyon pnömotoraks olarak teşhis edilerek göğüs tüpü takılmıştır. Tansiyon pnömotoraks ile dev bülü ayırt etmek çok zordur. Bu iki çok benzer antitenin tedavileri tamamen farklıdır. Bundan dolayı anamnez, fizik muayene ve radyolojik incelemede, doğru tanı için çok dikkatli olmalıyız., In the chest X-ray, we observe tension pneumothorax (TPX) as wide radiolucent view in a hemithorax and pushing the mediastinal structures contralateral. Giant bulla may mimic TPX with wide radiolucent view and mediastinal shift. The present report includes giant pulmonary bulla in 35-year-old woman. The giant bulla was diagnosed as a TPX in emergency, and chest tube was performed. The differentiation between TPX and a giant bulla may be very difficult. The therapies of these two similar entities are completely different. So that, we must be careful about anamnesis, physical examination and radiology for true diagnosis.
- Published
- 2009
16. Evaluation of cigarette smoking prevalence and behaviors in medical faculty hospital personnel
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Altın, Remzi, Kart, Levent, Ünalacak, Murat, Dutkun, Yalçın, Örnek, Tacettin, and Zonguldak Karaelmas Üniversitesi, Tıp Fakültesi
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Sigara İçme ,Hastane Personeli ,Hekim - Abstract
Bu çalışma Tıp Fakültesi Hastanesi çalışanlarında sigara içme prevelansını ve sigaraya karşı tutumlarını saptamak amacıyla planlanmıştır. Çalışmaya Tıp Fakültesi Hastanesi’nde çalışan toplam 590 personelden ulaşılabilen 453 kişi (%76.8) katılmıştır. Bu kişilere yüz yüze görüşme yöntemi ile 58 sorudan oluşan anket uygulanmıştır. Ankete katılanların yaş ortalaması 28.2 ± 3.8 olup bunların %48.6’sı kadın ve %51.4’ü erkektir. Olguların %41.3’ü sigara içicisi, %6.3’ü sigarayı içmiş bırakmış ve %52.4’ünün ise hiç sigara içmediği saptanmıştır. Erkeklerde sigara içim oranı %47.6, kadınlarda ise %25.7’dir. Çalışanlar içinde en az sigaranın memurlarda içildiği (%31.7) en fazla içimin ise işçilerde (%62.9) olduğu gö- rülmüştür. Hekimlerde sigara içim oranı %45.2 olarak bulunmuştur. Hastane çalışanlarında erkek ve bayanların tamamı göz önüne alındığında her iki grupta da sigara içim oranı işçilerde yüksektir (%78.4 erkek; %42.1 kadın). Sigara içen çalışanlar sigara bağımlılığı açısından ele alındı- ğında ağır bağımlılık düzeyi en yüksek yine işçi grubunda saptanmıştır ve bu durum istatistiksel olarak anlamlıdır (p
- Published
- 2004
17. Virtual endoscopy in the evaluation of post-tracheotomy laryngotracheal stenosis
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Uzun, Lokman, Savranlar, Ahmet, Altın, Remzi, Balbaloğlu, Şentürk Evrim, Gündoğdu, Sadi, and Zonguldak Bülent Ecevit Üniversitesi
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Boğaz ,Kulak ,Burun - Abstract
Giriş ve Amaç: Koronal ve aksiyel planda çekilmiş spiral bilgisayarlı tomografi görüntüleri ve bilgisayar programı kullanılarak, lümenli organların endoskopik görüntülerinin oluşturulması işlemi sanal endoskopi (SE) olarak bilinmektedir. Bu çalışmada trakeotomi yapılan ve daha sonra dekanüle edilmiş olan hastalarda trakeotomi bölgesinde oluşabilecek stenozun sanal endoskopi yöntemiyle değerlendirilmesi amaçlandı. Materyal Metod: Farklı sebeplerle trakeotomi yapılmış 8 hastanın larengotrakeal stenoz (LTS) yönüyle semptomları araştırıldı ve fizik muayeneleri yapıldı. Trakeotomi bölgesinin değerlendirilmesinde spiral aksiyel bilgisayarlı tomografi görüntülerinden elde edilen reformat sanal endoskopik görüntülerle trakeotomi bölgesinin endoluminal görüntüleri elde edildi. Stenoz derecesi Myer derecelendirme sistemine göre değerlendirildi. Bulgular: İki hastada Grade I stenoz saptandı. Stenozu olmayan hastalarda, trakea ön duvarda geçirilen operasyona sekonder trakeal halka düzensizliği ve yer yer trakeal kartilaj fraktürü gözlendi. Sonuç: SE, larengotrakeal bölge normal antomik yapılarında ve bu bölgede lokalize lezyonlarda, gerçeğine çok yakın endoluminal görüntü verebilmektedir. Videolarengoskopi ve/veya rijit veya fleksibl bronkoskopi ile lezyonun distal bölgesinin değerlendirilemediği durumlarda ve bronkoskopi yapılamayan hastalarda, yardımcı tanı yöntemi olarak uygulanabilir., Objective: Virtual endoscopy (VE) is three-dimensional representation of hollow structures generated from two-dimensional computerized tomography images by the help of computer. We aimed to evaluate the tracheotomy site by virtual endoscopy in patients who underwent tracheotomy. Material and Method: Eight patients who underwent tracheotomy for various reasons and were decanulated after a limited period entered the study. Three-dimensional reconstruction images of the tracheotomy site were generated and the degree of stenosis was graded according to Myer grading system for each patient. Results: Low grade tracheal stenosis was detected in two patients. Irregularity of the anterior tracheal wall and fractures of the tracheal rings secondary to tracheotomy were detected in all of the remaining six patients. Conclusion: VE can be used to obtain reliable endoluminal images of the lesions localized in the larynx and trachea. It can also be used as a supplementary diagnostic method when videolaryngoscopy and /or rigid or flexible bronchoscopy fail to show regions distal to the lesion.
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- 2004
18. Evaluation of cardiac autonomic activity in children with obstructive sleep apnea syndrome by heart rate variability
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Söğüt, Ayhan, Aydın, Mustafa, Altın, Remzi, Acun, Ceyda, Çınar, Fikret, Tomaç, Nazan, Kart, Levent, and Zonguldak Bülent Ecevit Üniversitesi
- Subjects
Pediatri ,Cerrahi - Abstract
Amaç: Obstrüktif uyku apne sendromu çocukluk yaş grubunda sık rastlanan bir bozukluktur. Etiyolojisinde başta adenotonsiller hipertrofi olmak üzere birçok faktör yer almaktadır. Kalp hızı değişkenliği kardiyak otonomik aktivitenin değerlendirilmesinde kullanılan noninvaziv bir yöntemdir. Bu amaçla obstrüktif uyku apneli çocuklarda 24 saat Holter EKG kullanılarak kardiyak otonomik aktivitenin değerlendirilmesi planlandı. Yöntem: Çalışmaya polisomnografi ile obstrüktif uyku apne sendromu tanısı konulan 22 hasta ile yaşı ve cinsiyeti uyumlu 20 sağlıklı çocuk kontrol grubu olarak dahil edildi. Her iki gruba 24 saat boyunca Holter elektrokardiyografi uygulanarak zaman ve frekans bağımlı kalp hız değişkenliği parametreleri hesaplandı. Frekans bağımlı analiz parametrelerinden HF, LF, VLF ve LF/HF, zaman bağımlı değişkenlerden SDNN, SDANN ve rMSSD kullanıldı. Bulgular: Obstrüktif uyku apne grubunda HF, SDNN ve SDANN değerleri anlamlı olarak azalırken (sırasıyla p, Objectives: Obstructive sleep apnea syndrome (OSAS) is a commonly encountered disease of childhood. Multiple factors are included in its etiology with the leading one being adenotonsillar hypertrophy. Heart rate variation is a noninvasive method that can be used to evaluate cardiac autonomic activity. This study was planned to investigate cardiac autonomic activity in children who were diagnosed as OSAS by using Holter ECG for 24 hours. Methods: Twenty two children who were diagnosed as OSAS by using polisomnography and age and sex matched 20 healthy children were included in this study. Holter ECG was applied for 24 hours to children in both groups and time and frequency dependent heart rate variability parameters were calculated. Frequency dependent analysis parameters HF, LF, VLF ve LF/HF and time dependent parameters SDNN, SDANN and rMSSD were used. Results: While HF, SDNN and SDANN decreased significantly in OSAS (p
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- 2004
19. The diagnostic value of the symptoms in the differentiation of habitual snoring and the pediatric obstructive sleep apnea syndrome
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Uzun, Lokman, Söğüt, Ayhan, Altın, Remzi, Uğur, Mehmet Birol, Çınar, Fikret, and Zonguldak Bülent Ecevit Üniversitesi
- Subjects
Boğaz ,Kulak ,Burun - Abstract
Giriş ve Amaç: Çocukluk çağı tıkayıcı uyku apnesi sendromu (TUAS), uyku sırasında tekrarlayan üst hava yolunun kısmi veya tam olarak tıkanması episodları ile karakterize olan ve çocukların % 2’ sinde görülen ciddi bir sağlık sorunudur. Habitüel horlama (HH), çocuklarda % 7-9 gibi yüksek oranda görülen bir semptomdur. Bu çocuklarda hipoksemi ve hiperkapni bulunmamakla birlikte, horlama ve beraberinde TUAS düşündüren semptomlar olması sebebiyle, bu iki durumun klinik ayrımı güçleşmektedir. Bu çalışmada, habitüel horlaması olan ve TUAS olan hastalar incelenip, semptomların, bu iki durumun ayrımındaki tanısal değerinin saptanması amaçlandı. Metod: Çalışmaya, her gece horlama şikayeti olan 74 çocuk dahil edildi. TUAS ile ilişkili olabilecek semptomlar yönüyle ayrıntılı anamnez alındı ve fizik muayeneleri yapıldı. Polisomnografi sonuçlarına göre TUAS ve HH’ lı sağlıklı çocuklar olarak sınıflandırıldı. Uykunun her saati başına oluşan apne ve hipopne sayısı 2 ve daha yukarı olan çocuklar TUAS olarak sınıflandırıldı. TUAS ve HH’ sı olan gruplarda semptomların görülme sıklığı ki-kare testiyle karşılaştırıldı. İki grup arasında görülme sıklığı bakımından istatistiksel olarak anlamlı farklılık bulunan semptomların, sensitivite ve spesifite değerleri hesaplandı. Her bir semptomun AHI ile olan korelasyonu Pearson Korelasyon testi ile hesaplandı. Bulgular: Sorgulanan semptomlar arasından, ağzı açık uyuma, huzursuz uyuma ve ağız solunumu semptomlarının görülme sıklığında iki grup arasındaki fark istatistiksel olarak anlamlı bulundu (x2, Objective: Obstructive sleep apnea syndrome (OSAS) in children is a serious disease , estimated to occur in approximately 2% of children and is characterized by repeated episodes of complete or partial upper airway obstruction during sleep. Habitual snoring (HS) is a common symptom seen in %7-9 of children. Although theres no hypercapnia and hypercapnia in HS, presence of snoring and other symptoms suggestive of OSAS in HS makes the clinical differentiation of these two clinical conditions a challenging one. In this study we evaluated children with HS and OSAS and assessed the diagnostic value of symptoms in the clinical differentiation of these two disorders. Method: 74 children with every night snoring symptom were included in this study. Detailed history with regard to OSAS symptoms is taken and physical examination is performed in each child. Children were classified in either OSAS or HS group according polysomnography results. Children with more than two spells of apnea or hypopnea per hour of sleep were classified as OSAS. The frequency of presence of symptoms in the HS and OSAS groups were compared with chi square test. When the frequency of any symptom was found statistically different between two groups, the sensitivity and specificity values were calculated. The correlation between each symptom and AHI analyzed by Pearson Correlation test. Results: The frequency of the presence of open mouth breathing, restlessness in sleep and open mouth sleeping symptoms were found to be significantly different between the two groups (x2
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- 2004
20. Investigation of obstructive sleep apnoea syndrome prevalence among long-distance drivers from Zonguldak, Turkey
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Akkoyunlu, Muhammed E., primary, Altın, Remzi, additional, Kart, Levent, additional, Atalay, Figen, additional, Örnek, Tacettin, additional, Bayram, Mehmet, additional, and Tor, Meltem, additional
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- 2013
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21. Clinical Factors Affecting the Direct Cost of Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
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Örnek, Tacettin, primary, Tor, Meltem, additional, Altın, Remzi, additional, Atalay, Figen, additional, Geredeli, Elif, additional, Soylu, Ömer, additional, and Erboy, Fatma, additional
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- 2012
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22. Insulin Resistance and Serum Leptin Levels in Men with Obstructive Sleep Apnea Syndrome
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Örnek, Tacettin, primary, Koçak, Erdem, additional, Koçak, Gülay, additional, Bakırtaş, Hatice, additional, Atmaca, Hulusi, additional, Can, Murat, additional, Bayraktaroğlu, Taner, additional, and Altın, Remzi, additional
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- 2011
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23. Evaluation of Respiratory Symptoms in Workers of a Rubber Factory
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Akca, Ayşe Semra Demir, primary, Demircan, Nejat, additional, Kart, Levent, additional, and Altın, Remzi, additional
- Published
- 2011
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24. Serum Asymmetric Dimethylarginine, Nitrate, Vitamin B12, and Homocysteine Levels in Individuals with Pulmonary Embolism
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Altuntaş, Murat, primary, Atalay, Figen, additional, Can, Murat, additional, Altın, Remzi, additional, and Tor, Meltem, additional
- Published
- 2011
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25. Original Article. Prognostic value of serum procalcitonin and C-reactive protein levels in critically ill patients who developed ventilator-associated pneumonia.
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Tanrıverdi, Hakan, Tor, Müge Meltem, Kart, Levent, Altın, Remzi, Atalay, Figen, and Sümbüloğlu, Vildan
- Subjects
PNEUMONIA ,C-reactive protein ,CALCITONIN ,CATASTROPHIC illness ,CHI-squared test ,FISHER exact test ,MECHANICAL ventilators ,LOGISTIC regression analysis ,RECEIVER operating characteristic curves ,DATA analysis software ,DESCRIPTIVE statistics ,MANN Whitney U Test ,PROGNOSIS - Abstract
INTRODUCTION: Ventilator-associated pneumonia (VAP) is an important cause of mortality and morbidity in critically ill patients. We sought to determine the prognostic value of procalcitonin (PCT) and C-reactive protein (CRP) kinetics in critically ill patients who developed VAP. METHODS: Patients who were admitted to the intensive care unit (ICU) and developed VAP were eligible. Patients were followed for 28 days after the pneumonia diagnosis and blood samples for PCT and CRP were collected on the day of the pneumonia diagnosis (D0), and days 3 (D3) and 7 (D7) after the diagnosis. Patients were grouped as survivors and non-survivors, and the mean PCT and CRP values and their kinetics were assessed. RESULTS: In total, 45 patients were enrolled. Of them, 22 (48.8%) died before day 28 after the pneumonia diagnosis. There was no significant difference between the survivor and non-survivor groups in terms of PCT on the day of pneumonia diagnosis or CRP levels at any point. However, the PCT levels days 3 and 7 were significantly higher in the non-survivor group than the survivor group. Whereas PCT levels decreased significantly from D0 to D7 in the survivor group, CRP did not. A PCT level above 1 ng/mL on day 3 was the strongest predictor of mortality, with an odds ratio of 22.6. CONCLUSION: Serum PCT was found to be a superior prognostic marker compared to CRP in terms of predicting mortality in critically ill patients who developed VAP. The PCT level on D3 was the strongest predictor of mortality in VAP [ABSTRACT FROM AUTHOR]
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- 2015
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- View/download PDF
26. THE DIAGNOSTIC EFFECTIVENESS OF THREE CARDINAL SYMPTOMS IN SLEEP APNEA SYNDROME WHEN ASKED ROUTINELY IN OUT-PATIENT VISITS
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Aktunç, Erol, additional, Altın, Remzi, additional, Demircan, Nejat, additional, Tor, Meltem, additional, Unalacak, Murat, additional, and Kart, Levent, additional
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- 2006
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27. Evaluation of carotid artery wall thickness with high-resolution sonography in obstructive sleep apnea syndrome
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Altın, Remzi, primary, Özdemir, Hüseyin, additional, Mahmutyazıcıoğlu, Kamran, additional, Kart, Levent, additional, Uzun, Lokman, additional, Özer, Tülay, additional, Savranlar, Ahmet, additional, and Aydın, Mustafa, additional
- Published
- 2005
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28. ENURESIS NOCTURNA PREVALENCE AND RISK FACTORS AMONG SCHOOL AGE CHILDREN IN NORTHWEST TURKEY
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Unalacak, Murat, primary, Söğüt, Ayhan, additional, Aktunç, Erol, additional, Demircan, Nejat, additional, and Altın, Remzi, additional
- Published
- 2004
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29. Analysis of Carcinoembriyonic antigen, neurone specific enolase, cytokeratin 21-1 and ferritin levels in coal miners
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Armutçu, Ferah, primary, Altın, Remzi, additional, Gürel, Ahmet, additional, Kart, Levent, additional, Unalacak, Murat, additional, and Çımrın, Arif H., additional
- Published
- 2004
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- View/download PDF
30. Serum Asymmetric Dimethylarginine, Nitrate, Vitamin B12, and Homocysteine Levels in Individuals with Pulmonary Embolism.
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Altuntaş, Murat, Atalay, Figen, Can, Murat, Altın, Remzi, and Tor, Meltem
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NITRATES ,VITAMIN B12 ,SERUM ,HOMOCYSTEINE ,PULMONARY hypertension ,PHYSIOLOGICAL transport of oxygen - Abstract
We aimed to analyze the pre- and posttreatment serum asymmetric dimethylarginine (ADMA), nitrate (NO
3 ), vitamin B12 and homocysteine levels in pulmonary embolism (PTE) patients and to determine the prognostic value of these variables in predicting chronic thromboembolic pulmonary hypertension (CTEPH). This study was conducted in 64 patients. The patients were classified into the two groups: patients with normal pulmonary artery pressure (PAP) (group I) and patients with high PAP with persistent lung perfusion defects or who died at the end of 3 months of therapy (group II). We found statistically significant differences between two groups with respect to the partial oxygen pressure, the oxygen saturation, and the PAP, but there was no difference between the two groups with respect to the pretreatment ADMA, NO3 , or homocysteine levels. The vitamin B12 levels were higher in group II. The NO3 levels increased and the ADMA and vitamin B12 levels decreased with treatment in both groups. These results suggest that these parameters are not predictive of the development of CTEPH. [ABSTRACT FROM AUTHOR]- Published
- 2011
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31. Malign Plevral Sıvıların Tanısında CYFRA 21-1, CA 19-9, CA-125 ve Mutant p53 Düzeylerinin De eri.
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Sevinç, Can, İşlekel, Hüray, Akkoçlu, Atila, Yenice, Sedef, Kılınç, Oğuz, İtil, Oya, Uçan, Eyüp Sabri, Çımrın, Arif, and Altın, Remzi
- Published
- 2000
32. Akut Masif Pulmoner Embolide Lokal İntravasküler Trombolitik Uygulama: Olgu Sunumu.
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Akkoyunlu, Muhammet Emin, Altın, Remzi, Kart, Levent, Tor, Meltem, Altunkaya, Süleyman Aykut, Atalay, Figen, and Örnek, T.
- Subjects
- *
PULMONARY embolism , *THROMBOLYTIC therapy , *HYPOXEMIA , *HYPOTENSION , *ANGIOGRAPHY ,PULMONARY artery diseases - Abstract
Pulmonary embolism is a common disease with high mortality and morbidity rates. Incidence of the disease is increasing associated with the development in the diagnostic methods. Anticoagulation is the standard treatment for pulmonary embolism. However, thrombolytic treatment is a significant alternative in acute massive pulmonary embolism as it provides rapid cloth resolution. Although a number of studies related with thrombolytic treatment and its indications are published recently, patterns and schemes of application are still remains as a debate. Herein, 72 year old patient with pulmonary embolism is presented. He was symptomatic with hypoxemia and hypotension. Diagnosis was made with spiral pulmonary angiography as "acute massive pulmonary embolism". He developed hemoptysis as a result of intravenous thrombolytic treatment (rt- PA: recombinant tissue plasminogen activator) and was successfully treated by local intravascular thrombolytic treatment (rt-PA). [ABSTRACT FROM AUTHOR]
- Published
- 2007
33. Characteristics of Newly Diagnosed Asthma Patients Living in Zonguldak Province of Turkey
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Tor, Meltem M., Akbulut, Suna, Altin, Remzi, and Kart, Levent
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- 2004
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34. Insulin Resistance and Serum Leptin Levels in Men with Obstructive Sleep Apnea Syndrome.
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Koçak, Erdem, Koçak, Gülay, Ãrnek, Tacettin, Bakırtaş, Hatice, Atmaca, Hulusi, Can, Murat, Bayraktaroğlu, Taner, and Altın, Remzi
- Abstract
Aim: The aim of this study was to assess the insulin resistance and serum leptin levels in patients with obstructive sleep apnea syndrome (OSAS), and to compare body mass indexes (BMI) of OSAS patients with matched controls without OSAS. Method: Twenty eight patients having apnea-hypopnea index (AHI)≥5 included in the study. Thirty two healthy subjects assumed as a control group. Venous blood was obtained in the fasting state for the measurement of glucose, insulin and leptin levels. Insulin resistance index was based on the homeostasis model assesment method (HOMA-IR). Result: There was no significant difference in the serum leptin levels (control group, 32.88±24.22 ng/ml, OSAS group, 24.93±25.84 ng/ml) and HOMA-IR (control group, 3.01±1.81, OSAS group, 2.58±1.21) between control group and OSAS patients. Insulin resistance and circulating plasma leptin concentrations in OSAS patients were independent of the AHI and were not different from the control group. Conclusion: We concluded that insulin resistance and plasma leptin concentrations are mostly associated with the degree of obesity and BMI. Those parameters seem not to be related with the AHI in OSAS patients. [ABSTRACT FROM AUTHOR]
- Published
- 2011
35. Evaluation of Respiratory Symptoms in Workers of a Rubber Factory.
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Semra Demir Akca, Ayşe, Demircan, Nejat, Kart, Levent, and Altın, Remzi
- Abstract
Aim: In this study, our objective was to investigate whether there is any relationship between working in the rubber industry and having respiratory symptoms. Method: This study was performed on 141 workers of a rubber factory. Anamnesis, physical examination and pulmonary function tests (PFT) were evaluated. Peak Expiratory Flow (PEF) follow-up and skin Prick Test were administered to the patients according to the results of respiratory system complaints, physical examination and PFT. Result: One hundred and forty one workers who accepted to participate in the study consisted of 116 (82.3%) males and 25 females (17.7%). In the comparison group with greater exposure results were obtained in the normal range, however the parameters of FEV1/FVC and FEF25-75 (%) were lower in the greater exposure group. This difference was statistically significant (p<0.05). Variability was greater than 20% in 9 (6.3%) workers in the evaluation of PEF-meter follow-up forms. Conclusion: In conclusion, our study has demonstrated that exposure to dust and smoking in rubber industry seem to be associated with the development of occupational respiratory symptoms and diseases. That's why, control of dust exposure and cessation of smoking is important in prevention of this situations. [ABSTRACT FROM AUTHOR]
- Published
- 2011
36. Insulin Resistance and Serum Leptin Levels in Men with Obstructive Sleep Apnea Syndrome.
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Ko‡ak, Erdem, Ko‡ak, Glay, ™rnek, Tacettin, Bakırtaş, Hatice, Atmaca, Hulusi, Can, Murat, Bayraktaroğlu, Taner, and Altın, Remzi
- Subjects
- *
BLOOD testing , *STATISTICAL correlation , *ELECTROENCEPHALOGRAPHY , *ELECTROMYOGRAPHY , *ENZYME-linked immunosorbent assay , *INSULIN resistance , *OXIMETRY , *SLEEP apnea syndromes , *T-test (Statistics) , *LEPTIN , *POLYSOMNOGRAPHY , *EQUIPMENT & supplies , *BODY mass index , *CASE-control method , *DATA analysis software , *DESCRIPTIVE statistics - Abstract
Aim: The aim of this study was to assess the insulin resistance and serum leptin levels in patients with obstructive sleep apnea syndrome (OSAS), and to compare body mass indexes (BMI) of OSAS patients with matched controls without OSAS. Method: Twenty eight patients having apnea-hypopnea index (AHI)≥5 included in the study. Thirty two healthy subjects assumed as a control group. Venous blood was obtained in the fasting state for the measurement of glucose, insulin and leptin levels. Insulin resistance index was based on the homeostasis model assesment method (HOMA-IR). Result: There was no significant difference in the serum leptin levels (control group, 32.88±24.22 ng/ml, OSAS group, 24.93±25.84 ng/ml) and HOMA-IR (control group, 3.01±1.81, OSAS group, 2.58±1.21) between control group and OSAS patients. Insulin resistance and circulating plasma leptin concentrations in OSAS patients were independent of the AHI and were not different from the control group. Conclusion: We concluded that insulin resistance and plasma leptin concentrations are mostly associated with the degree of obesity and BMI. Those parameters seem not to be related with the AHI in OSAS patients. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
37. Leptin levels in children with obstructive sleep apnea syndrome.
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Söğüt A, Açıkgöz Ş, Uzun L, Uğur MB, Altın R, Dağlı E, Kaditis A, and Ersu R
- Subjects
- Adolescent, Body Mass Index, Child, Female, Humans, Infant, Male, Polysomnography, Severity of Illness Index, Sleep Apnea, Obstructive complications, Snoring etiology, Biomarkers blood, Leptin blood, Pediatric Obesity, Sleep Apnea, Obstructive blood
- Abstract
Introduction: The aim of this study is to assess the effect of obstructive sleep apnea syndrome (OSAS) severity on leptin levels in children., Patients and Methods: Children with habitual snoring underwent overnight polysomnography. Fasting venous blood samples were obtained between 8 AM and 9 AM, following the night of the sleep study. Children with an apnea-hypopnea index of ≥ 5/h were included in the moderate-to-severe OSAS group while those with an apnea-hypopnea index of < 5/h formed the mild OSAS/primary snoring group., Result: 47 children (51% male and 49% female; mean age 7.8 ± 2.6 years) were recruited. Twenty seven participants were diagnosed with moderate-to-severe OSAS, and twenty children who had AHI < 5 were included in the mild OSAS/primary snoring. The two groups did not differ regarding age, gender and body mass index z score (p> 0.05). Furthermore there were no differences in log serum leptin levels (p= 0.749). Log serum leptin levels correlated with the BMI z score in the whole study group (p= 0.001; r= 0.499) but they were not associated with apnea-hypopnea index, mean and lowest oxygen saturation during sleep., Conclusions: Serum leptin levels are affected by adiposity but not by OSAS severity among children with habitual snoring.
- Published
- 2016
38. Prognostic value of serum procalcitonin and C-reactive protein levels in critically ill patients who developed ventilator-associated pneumonia.
- Author
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Tanrıverdi H, Tor MM, Kart L, Altın R, Atalay F, and SumbSümbüloğlu V
- Abstract
Introduction: Ventilator-associated pneumonia (VAP) is an important cause of mortality and morbidity in critically ill patients. We sought to determine the prognostic value of procalcitonin (PCT) and C-reactive protein (CRP) kinetics in critically ill patients who developed VAP., Methods: Patients who were admitted to the intensive care unit (ICU) and developed VAP were eligible. Patients were followed for 28 days after the pneumonia diagnosis and blood samples for PCT and CRP were collected on the day of the pneumonia diagnosis (D0), and days 3 (D3) and 7 (D7) after the diagnosis. Patients were grouped as survivors and non-survivors, and the mean PCT and CRP values and their kinetics were assessed., Results: In total, 45 patients were enrolled. Of them, 22 (48.8%) died before day 28 after the pneumonia diagnosis. There was no significant difference between the survivor and non-survivor groups in terms of PCT on the day of pneumonia diagnosis or CRP levels at any point. However, the PCT levels days 3 and 7 were significantly higher in the non-survivor group than the survivor group. Whereas PCT levels decreased significantly from D0 to D7 in the survivor group, CRP did not. A PCT level above 1 ng/mL on day 3 was the strongest predictor of mortality, with an odds ratio of 22.6., Conclusion: Serum PCT was found to be a superior prognostic marker compared to CRP in terms of predicting mortality in critically ill patients who developed VAP. The PCT level on D3 was the strongest predictor of mortality in VAP.
- Published
- 2015
- Full Text
- View/download PDF
39. The benefit of expiratory-phase quantitative CT densitometry in the early diagnosis of chronic obstructive pulmonary disease.
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Beşir FH, Mahmutyazıcıoğlu K, Aydın L, Altın R, Asil K, and Gündoğdu S
- Subjects
- Adult, Early Diagnosis, Exhalation, Humans, Male, Middle Aged, Pulmonary Disease, Chronic Obstructive physiopathology, Pulmonary Disease, Chronic Obstructive diagnostic imaging, Tomography, X-Ray Computed
- Abstract
Purpose: We aimed to compare the inspiratory and expiratory quantitative computed tomography (CT) densitometric data of healthy volunteers, individuals with chronic obstructive pulmonary disease (COPD) risk, and COPD patients to aid in the early diagnosis of COPD., Materials and Methods: Of the study patients, 14 were healthy volunteers (Group I), 12 were patients at risk for COPD (Group II), and 13 were COPD patients (Group III). The high-resolution CT was performed at three levels (the upper, middle, and lower parts of the lungs). All images were evaluated with a specific program for the segmentation of pulmonary parenchyma. The mean lung density (MLD) was measured, and the emphysema index (EI) was calculated using this program., Results: Both MLD values and calculated EI ratios showed significant differences between Groups I and III, and Groups II and III in both expiratory and inspiratory phases (P < 0.05). However, in the comparison of healthy volunteers and patients at risk for COPD (Group I and II), only expiratory-phase MLD values showed statistically significant difference (P < 0.001)., Conclusion: In patients at risk for COPD, expiratory-phase MLD measurements can be used as an early diagnostic method.
- Published
- 2012
- Full Text
- View/download PDF
40. Prevalence of major obstructive sleep apnea syndrome symptoms in coal miners and healthy adults.
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Kart L, Dutkun Y, Altın R, Ornek T, and Kıran S
- Subjects
- Adult, Case-Control Studies, Disorders of Excessive Somnolence epidemiology, Disorders of Excessive Somnolence pathology, Humans, Male, Occupational Diseases pathology, Polysomnography, Prevalence, Sleep Apnea, Obstructive pathology, Smoking adverse effects, Snoring epidemiology, Snoring pathology, Turkey epidemiology, Coal Mining, Occupational Diseases epidemiology, Sleep Apnea, Obstructive epidemiology
- Abstract
Obstructive sleep apnea syndrome obstructive sleep apnea syndrome is associated with symptoms including habitual snoring, witness apnea and excessive daytime sleepiness. Also obstructive sleep apnea syndrome is related to some occupations which are needed attention for work accident. We aimed to determine the prevalence of snoring, witnessed apnea and excessive daytime sleepiness in coal workers and healthy adults in Zonguldak city center, and also evaluate the differences between these groups. This study consisted of 423 underground coal workers and 355 individuals living in centre of Zonguldak. Study and comparison group were chosen by nonstratified randomized sampling method. Data were collected by a questionnaire that included information regarding snoring, witnessed apnea and excessive daytime sleepiness. Mean age was 43.3 ± 6.05 years in miners and 44.3 ± 11.8 years in comparison group. In miners, snoring frequency was determined as 42.6%, witnessed apneas were 4.0%, and daytime sleepiness were 4.7%. In comparison group, these symptoms were 38.6%, 4.8% and 2.8% respectively. There were no statistical differences between coal workers and comparison group in these symptoms. Also snoring prevalence was higher in smoker miners. We found that major symptoms of obstructive sleep apnea syndrome in coal workers are similar to general population in Zonguldak. Further studies that constucted higher populations and with polysomnography are needed to evaluate these findings.
- Published
- 2010
41. Working conditions and pneumoconiosis in Turkish coal miners between 1985 and 2004: a report from Zonguldak coal basin, Turkey.
- Author
-
Tor M, Oztürk M, Altın R, and Cımrın AH
- Subjects
- Adult, Anthracosis diagnosis, Anthracosis etiology, Coal Mining, Dust analysis, Humans, Inhalation Exposure, Male, Occupational Diseases diagnosis, Occupational Exposure analysis, Prevalence, Turkey epidemiology, Young Adult, Anthracosis epidemiology, Occupational Diseases epidemiology
- Abstract
In Turkey, bituminous coal mining is performed only in Zonguldak coal basin since 1940. Pneumoconiosis surveillance programs and dust control measures are in effect, but published pneumoconiosis data from this area is lacking. In this study, we aimed to evaluate the change in prevalence and case detection between 1985 and 2004 and assess the correlation between the dust concentration in workplaces and the prevalence of pneumoconiosis. Data on respirable dust concentrations and number of workers diagnosed as pneumoconiosis between 1985 and 2004 were obtained from Turkish Coal Enterprises authorities. Mean respirable dust concentrations in workplaces underground and on the ground were 1.66 mg/m(3) and 0.73 mg/m(3) respectively. Total number of workers decreased from 38.231 in 1985 to 12.261 in 2004 including 8932 underground workers. In this period, pneumoconiosis has not been reported in the ground workers. Incidence of pneumoconiosis ranged between 0.17-2.8 percent and prevalence ranged between 1.23-6.23 percent between 1985 and 2004. Radiologic opacities compatible with pneumoconiosis were predominantly small opacities. This is the first report about the incidence and prevalence rate of coal worker's pneumoconiosis in the main coal mining area of Turkey. Dust measurement and screening standards should be improved and adapted to international standards and we conclude that surveillance data should be closely monitored in this region and further epidemiologic studies in this area are warranted.
- Published
- 2010
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