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Energy literacy has become acritical issue in recent years. The purpose of this study was to examine the contributions of epistemological beliefs to energy literacy in lower-secondary school students in Turkey. Data were collected via self-report questionnaires from 656 lower-secondary school students in the Aegean Region of Turkey. To address the research questions, Pearson correlation and multiple regression were implemented. Descriptive results revealed that students had a low energy literacy mean score in the knowledge dimension whereas they had moderate mean scores in the behavioral and affective dimensions. Multiple regression results yielded statistically significant contributions of epistemological beliefs to energy literacy. Analysis revealed that the reasoning dimension positively predicted the energy literacy in the knowledge dimension whereas the authority and accuracy dimension did negatively. The results of this study suggest that advancing students' epistemological beliefs can be a way to increase students' energy literacy levels.

The aim of this study is to examine the effect of educational movies on the pedagogical beliefs of pre-service teachers. The study was conducted using phenomenology design, one of the qualitative research designs. In the study, 12 educational movies were used. Criterion sampling, one of the purposeful sampling methods, was used in the study. 25 first-year pre-service teachers were included in the study. Each week a movie was watched and pedagogically and critically oriented discussions were held about the movie. Weekly evaluations were obtained through pre-service teachers' written reports. A semi-structured interview form and movie evaluation reports filled out by pre-service teachers were used as data collection tools. The data obtained from the interviews and movie evaluation reports before and after the implementation were analyzed comparatively and transformed into findings. When the findings were analyzed, it was concluded that there were changes in pre-service teachers' knowledge, skills, attitudes and awareness levels towards the teaching profession. In general, it is thought that educational movies may have an effect on pre-service teachers' pedagogical beliefs. [Note: The publication year (2022) shown on the PDF is incorrect. The correct publication year for this article is 2023.]

This article addresses the challenges that special education school principals face in Türkiye. The literature indicated that there are a variety of challenges that impact school principals and school management. Most of these challenges were based on school personnel. Shortage and attrition of Special Education (SPED) teachers, lack of teaching and knowledge on teaching students with disabilities, some work-related challenges, and lack of collaboration and advocacy among school staff were the challenges indicated in the literature. There are few Turkish studies that explore the challenges that SPED school administrators face. Therefore, the purpose of this study was to explore what challenges Turkish SE school principals face and whether these challenges are different from those reported in the literature. A semi-structured interview was conducted with 12 school principals. The results of this study indicated that some challenges that Turkish SPED principals have been facing were consistent with the literature, while others were not indicated in the literature. Implications for practice and directions for future research are presented.

Climate change put most species' survival in danger because it substantially affects the climate in which the species live, the quality of the water they drink, as well as the temperature of the air or water. When climate change increases the temperature of the climate, excessive evaporation occurs in lands, lakes, seas, and oceans. Our purpose in this paper is to introduce a mathematical modelling activity embedded in Problem Based Learning (PBL) that allows students to investigate factors related to evaporation. Mathematical modelling is a popular technique of teaching mathematic concepts and skills and a method of inquiry about scientific phenomena that interests scientists. In the present activity, students use secondary data from trusted websites to test their hypotheses. Students are engaged in analyzing and interpreting data, generating and testing models, and discussing and presenting findings with their peers. The activity allows students the opportunity to examine the relationship between variables and predict one variable using the other. The activity has the potential to foster students' computational and higher-order thinking skills.

Introduction: Depending on the disease’s stage, type 2 diabetes can impact anxiety, depression, and health-related quality of life. This study aimed to compare the health-related quality of life, anxiety, and depression of men and women recently diagnosed with type 2 diabetes to that of healthy controls. Methods: There were 100 newly diagnosed type 2 diabetic patients (50 females and 50 males), as well as 100 healthy controls (50 females and 50 males). Each participant receives three questionnaires: the Short-Form Health Survey (SF-36), the Beck Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI). Results: Compared to controls, patients’ scores on the SF-36 for total, physical, and mental health were lower for both genders. Compared to controls, the female patients’ BAI and BDI scores were greater. Both male and female diabetes patients had a negative correlation between their SF-36 total score and fasting plasma glucose. Additionally, the female patients’ fasting plasma glucose and BDI score showed a positive correlation. Conclusions: In both genders, patients with recently diagnosed type 2 diabetes had a lower health-related quality of life compared to controls. However, the anxiety and depression levels of only female diabetic patients worsened when compared to controls. We suggest considering gender differences in the symptomatology of anxiety and depression among newly diagnosed type 2 diabetic patients to develop more effective ways to manage their condition, such as comprehensive and early intervention.

Abstract Chest X-rays are the most commonly performed medical imaging exam, yet they are often misinterpreted by physicians. Here, we present an FDA-cleared, artificial intelligence (AI) system which uses a deep learning algorithm to assist physicians in the comprehensive detection and localization of abnormalities on chest X-rays. We trained and tested the AI system on a large dataset, assessed generalizability on publicly available data, and evaluated radiologist and non-radiologist physician accuracy when unaided and aided by the AI system. The AI system accurately detected chest X-ray abnormalities (AUC: 0.976, 95% bootstrap CI: 0.975, 0.976) and generalized to a publicly available dataset (AUC: 0.975, 95% bootstrap CI: 0.971, 0.978). Physicians showed significant improvements in detecting abnormalities on chest X-rays when aided by the AI system compared to when unaided (difference in AUC: 0.101, p

Abstract Background The aim of combining hyperthermic intrathoracic chemotherapy (HITHOC) with surgery is to achieve local control in patients with pleural malignancies. Liver and kidney dysfunction resulting from this procedure have been reported in the literature. The objective of the study is to examine whether the laboratory abnormalities observed during the initial period persist until day 30. Methods The study conducted a retrospective analysis of the blood glucose levels, renal function markers, and hepatic function markers of 30 patients who underwent pleurectomy-decortication and HITHOC for pleural mesothelioma from January 2010 to April 2022. The measurements were taken in the postoperative period on the first four and 30th days. The study analyzed the initial and final laboratory results caused by the procedure. Results Out of the total of 30 patients, 29, 28, 14, and 12 patients had elevated glucose levels on the first four days after the surgery, respectively. There was no association between glucose abnormalities and preoperative-postoperative diabetes mellitus. A minority of patients experienced atypical alterations in kidney and liver functions during the initial postoperative period. There was no apparent relationship between the renal and hepatic functions in the early and late periods after the surgery. Conclusion Although there were fluctuations in glucose levels and renal and hepatic functions in the early period after surgery, there were no persistent alterations in these parameters by day 30. Elevated glucose levels during the early period were not associated with the development of newly diagnosed diabetes mellitus after surgery. The findings of our study provide evidence that HITHOC is a favorable and well-tolerated treatment option for mesothelioma.

Purpose: The aim of this study was to shed some light on the extent to which digital literacy, epistemological belief and reading motivation and engagement predict pre-service teachers' capabilities in teaching 21st century skills. Design/methodology/approach: 21st Century Skills Teaching Scale, Internet based Epistemological Beliefs Scale, Internet based Reading Motivation and Engagement Scale as well as Digital Literacy Scale were used to collect the data. A total of 512 pre-service teachers from four universities in Türkiye participated in the study. Descriptive statistics, correlation and structural equation model fitness tests were performed by using SPSS 24.0 and AMOS 22.0. Findings: First, the results of the correlations analysis indicated that there were statistically significant positive correlations among measured variables. Second, the results of the path and SEM model fit tests demonstrated that all the model fit indices of X[superscript 2]/df, TLI, CFI, RMSEA met the acceptable criteria and were shown to be an adequate model structure. Finally, the results demonstrated strong evidence for predicting effects of digital literacy, epistemological belief as well as reading motivation and engagement on teaching 21st century skills. Research limitations/implications: This study is limited by the fact that the evidence relies solely on pre-service teachers' self-reporting. Secondly, although the hypothesised model explained 45.2% variance of pre-service teachers' competence in the 21st century skills, 54.8% of it remains unexplained. Originality/value: The results of this study suggest important implications for teaching programs as they underscore the importance of digital literacy on epistemological beliefs, reading motivation and competence in teaching 21st century skills.

Abstract Solar photovoltaic energy is a vital renewable resource because it is clean, endless, and pollution‐free. Due to the fast growth of the semiconductor and power electronics sectors, photovoltaic (PV) technologies are climbing significant attention in modern electrical power applications. Operating PV energy conversion systems at the maximum power point is essential for getting the maximum power output and raising efficiency. This paper proposes a regression‐based Perturb and Observe method to quickly find a global maximum power point, avoiding being stuck in local maxima, likewise analytical and metaheuristic methods. The improved control focuses on the narrowed search areas by linear and non‐linear regression analyses using the generated PV model on a flexible Python environment. Furthermore, the method's accuracy is validated in real time under variable temperatures, irradiations, and loads. This method was proven with a hardware implementation. The proposed method is more than 98% accurate and can withstand long‐term modelling. The suggested regression‐based perturbation and observation method provided a short learning time and easy implementation. Additionally, the dynamic recorded results can be visualized for researchers to utilize efficiently.

Aim: In recent years, physicians practicing in Turkey have started to face various legal processes such as patient complaints, medical malpractise,administrative disciplinary proceedings, criminal cases, and compensation lawsuits more frequently. This study aimed to evaluate the experiences and opinions of physicians on the subject. Materials and Methods: The study was conducted in the form of a questionnaire, and the questions directed to the participants were created through the application called Google Forms and were requested to be filled in electronically. Results: The age range of 30-35 years (32.6%) and 1-5 years of professional experience (34.4%) had the highest participation rate. Among the physicians who participated in the survey, 80.2% stated that they had complained at least once, 81.5% stated that they had testified at least once in judicial institutions, and 46.8% stated that they had attended a hearing in court. Of the physicians, 21.8% received administrative penalties and 7.9% received judicial penalties. According to the results of our study, general practitioners and emergency medicine specialists were the most frequently complained about physicians who were prosecuted in judicial courts for assault,insult, and assault. Conclusion: Efforts should be made to reduce the forensic concerns of physicians, and a common perspective on the issue should be developed by creating platforms where medical and legal sciences come together.

Teachers' career motivation is an important factor affecting the education process. In this study, the relations between science teachers' career motivations and demographic variables (gender, school location and professional experience) were examined. A total of 136 science teachers working at state middle schools in Mugla Province participated in the study. FIT-Choice Scale was used as data collection tool. Data were collected in the Spring 2019 semester. In data analysis, descriptive statistics, independent sample t-test and one-way ANOVA tests were used. The results of the analysis showed that the career motivation of science teachers was at moderate level. In terms of gender, differences were found in the sub-dimensions of expertise, difficulty, social impact, and fallback career. In addition, analysis showed that there was a difference in the sub-dimensions of difficulty, social status, social pressure, enhance social equality, social contribution, determining the future of students and previous experiences in terms of school location. In terms of professional experience, in only the sub-dimension of job security, a statistically significant difference was found. The results of the study suggest that teachers should receive more financial and moral support from their environment.

Emotion is an important factor that affects people's lives in many areas including their productivity at work. For this reason, teacher emotions, defined as emotional states related to the learning activities in educational settings, are very important in the classroom environment. In this study, the relationships of science teachers' emotions with demographic and school variables were examined. 185 science teachers at public and private middle schools in Mugla Province participated in the research in the fall semester of 2019-2020. In the study, data were collected using the Personal Information Form and the Teachers' Instructional Emotions Scale. In descriptive analyzes, mean and standard deviation were used whereas non-parametric Mann Whitney U and Kruskal Wallis H tests were used to determine the relational findings since the data did not show normal distribution. It was found that science teachers' positive emotions of pride, pleasure, and hope had a higher mean value than negative emotions of anger, anxiety, and frustration. Relational analysis revealed that there was significant difference between science teachers' instructional emotions in terms of gender, age, professional experience, school location and the socio-economic status of the school. There was no significant difference in the weekly course hours, weekend course hours and class size variables.

In this research, it was aimed to examine the effects of interdisciplinary science activities on 5th grade students' creative problem-solving skills and 21st century skills. The study group consisted of 50 5th grade students, 26 girls and 24 boys, were studying at a public school in Ankara, Çankaya district in the 2018-2019 academic year. The Creative Problem Solving Attribute Inventory and the 21st Century Skills Tests were applied to the students before and after the application. The obtained data were analyzed using a statistical program. The "Dependent Groups t-Test" and "Cohen's d" test, which are parametric tests, were used in the analysis of the Creative Problem Solving Attribute Inventory and the 21st Century Skills Test. In line with the evaluations made, it was concluded that interdisciplinary science activities positively affected students' creative problem solving skills and 21st century skills. Suggestions were made based on the findings.

Cyclophosphamide (CP) is an alkylating anticancer drug with broad clinical application that is highly effective in the treatment of cancer and non-malignant diseases. However, the main limiting effect of CP is multi-organ toxicity due to damage to normal tissues. The aim of this study is to compare the hepatoprotective potential of selenium (Se) and boron (B) in CP-induced liver injury in experimental rats. The rats were randomly divided into six equal groups: Control (saline), 200 mg/kg CP (administered once on the fourth day of the experiment), 1.5 mg/kg Se (administered once/time daily for 6 days), 20 mg/kg B (administered once/time daily for 6 days), Se + CP and B + CP administered intraperitoneally (i.p.). Administration of CP leads to an increase in the levels of apoptotic markers (Bax, caspase-3), the apoptotic signaling pathway (Nrf2), oxidative stress indicators (TOS, OSI), lipid peroxidation markers (MPO, MDA), inflammation levels (NF-kB, TNF-α, IL-1β, IL -6), liver function markers (ALT, AST, ALP), while apoptosis markers (Bcl-2), apoptosis pathway (Keap-1), oxidative stress indicator (TAS), inflammation (IL -10) and intracellular antioxidant defense system (SOD, CAT, GPx and GSH) decreased. In addition, degeneration of hepatocytes and congestion in the central veins were observed. In contrast, in the groups administered Se and B with CP, the changes that occurred were reversed. However, it was found that Se protects the liver slightly better against CP damage than B. The protective effect of Se and B against the toxic effects of CP on the antioxidant markers SOD, CAT and GPx1 was also investigated in silico. The in silico results were consistent with the in vivo results for SOD and CAT, but not for GPx1.

This study aimed to investigate the effect of changing the indoor unit air flow rate on the performance of an automobile heat pump with a suction line heat exchanger. Using a four-way valve, the automotive heat pump system was developed by reversing the refrigerant direction in the automobile air conditioning system, excluding the compressor. A suction line heat exchanger was added to the test system to enhance heat transfer between the liquid and suction lines of the automotive heat pump system. Performance comparisons were first performed for R134a and R1234yf by disabling the suction line heat exchanger. Then, the suction line heat exchanger was activated for R1234yf, and the tests were repeated. Performance comparisons were made for two different compressor speeds and three different indoor unit airflow speeds. It was found that using the heat exchanger in R1234yf operations improved the heating capacity, compressor discharge temperature and coefficient of performance by approximately 1.8 %, 5.1 % and 5.9 %, respectively. The heating capacity of the heat pump system using R134a, R1234yf, and R1234yf with the suction line heat exchanger was determined to be in the range of 2.46–3.29 kW, 2.35–3.04 kW, and 2.39–3.11 kW, respectively. An increase in the airflow speed of the indoor unit from 1.4 m s−1 to 3.2 m s−1 resulted in an average decrease of approximately 12.3 % in the compressor discharge temperature. In contrast, the heating capacity and coefficient of performance increased by approximately 11.8 % and 14.4 % on average, respectively, for R1234yf operations with the heat exchanger. This study revealed that by optimizing the air flow rate in the R1234yf heat pump system with a suction line heat exchanger, improvements in the heating capacity and coefficient of performance can be achieved, thus providing better thermal comfort in the passenger compartment.

Background: The rate of death and disability due to acute ischemic stroke ranks second in the world. In this study it was planned to analyze the demographic characteristics and additional diseases in the etiology as well as radiological imaging and laboratory values in patients with ischemic stroke. Materials and Methods: This study was conducted retrospectively by analyzing the patients hospitalized with the diagnosis of ischemic stroke from the emergency department between 01.01.2022 and 31.12.2022. Routine laboratory values, lipids, vitamin levels, radiological imaging and tests for etiology were analyzed in the patients. Results: One hundred seventy seven patients were analyzed in the study. 53.1% of the patients were male. The mean age was 75±12.75 years. The most common comorbidities were hypertension, diabetes and hyperlipidemia. As ischemic infarction, involvement was most common in the areas fed by the middle cerebral artery. In the carotid and/or vertebral doppler ultrasonography performed in the patients, plaque was observed in the vessels at a rate of 83.1%. According to the transthoracic echocardiographic findings, 79.3% of the patients were found to have heart valve pathology. Pathologically the majority of patients had hyperglycemia, vitamin D deficiency and low HDL cholesterol levels. Thrombolytic therapy was applied in six patients and three patients benefited and one patient died due to bleeding. 13.6% of the patients were treated in the intensive care unit. Conclusion: The risk of ischemic stroke increases in advanced age. Hypertension and diabetes are among the most important risk factors. Vitamin D and vitamin B12 deficiency and folic acid deficiency pose a risk in terms of atherosclerosis. At the same time, low HDL cholesterol levels increase the risk of stroke. These factors which are considered as preventable causes in etiology should be controlled with treatment.

The purpose of this study was to examine the relationship between physical education teachers' recreational activity participation, leisure time satisfaction, and cognitive flexibility. The relationship between the benefits that physical education teachers derive from participating in recreational activities, their levels of satisfaction during leisure time, and their cognitive flexibility. A total of 515 participants took part in the research. Out of these, 191 were female and 324 were male. All the participants were employed by physical education departments in Antalya. The teachers who participated in the research were selected using the homogeneous sampling method, which is one of the purposeful sampling methods, and voluntary participation was considered in determining the participants. In the collection of research data, the scales were filled in electronically. The Personal Information Form developed by the researcher was used to obtain sociodemographic data. In addition, the Recreation Utility Scale designed by Ho in 2008 (26), the Leisure Time Satisfaction Scale developed by Beard and Ragheb in 1980 (6), and the Cognitive Flexibility Scale developed by Martin and Rubin in 1995 (34) were used to measure how individuals spend their ‘leisure time’ physically, psychologically, and socially. The data obtained from the scales were analyzed and interpreted through statistical methods based on the research problems. SPSS version 25 statistical programs was used for data analysis. Descriptive statistical analyses, including frequency and percentage distributions of the responses to the scale questions, as well as arithmetic mean and standard deviation scores, interpretive statistical analyses were performed based on the results of the normality analysis of the data, and correlation (Pearson) analysis was used to determine the relationships between variables. The reliability level for this study was accepted as 0.05. When the findings were examined, according to the results of the research, it can be said that the physical education teachers participating in the research generally think that recreational activities are beneficial in terms of physical, psychological, and social aspects. However, they exhibited an attitude that recreational activities contribute more to individuals' physical and psychological characteristics while contributing less to their social lives or socialization. Additionally, it can be said that they are generally satisfied with leisure activities, but they believe that the places where these activities are carried out need to be better designed or increased. The cognitive flexibility levels of physical education teachers were found to be close to "somewhat agree" and they have a positive cognitive flexibility. According to the findings obtained regarding the sub-problem of the research, "Is there a statistically significant relationship between the benefits of physical education teachers' participation in recreational activities, their leisure satisfaction, and cognitive flexibility levels?", it was determined that there were statistically significant (p

Abstract Visual clinical diagnosis of dermatoses in people of color (PoC) is a considerable challenge in daily clinical practice and a potential cause of misdiagnosis in this patient cohort. The study aimed to determine the difference in visual diagnostic skills of dermatologists practicing in Germany in patients with light skin (Ls) and patients with skin of color (SoC) to identify a potential need for further education. From April to June 2023, German dermatologists were invited to complete an online survey with 24 patient photographs depicting 12 skin diseases on both Ls and SoC. The study’s primary outcomes were the number of correctly rated photographs and the participants’ self-assessed certainty about the suspected visual diagnosis in Ls compared to SoC. The final analysis included surveys from a total of 129 dermatologists (47.8% female, mean age: 39.5 years). Participants were significantly more likely to correctly identify skin diseases by visual diagnostics in patients with Ls than in patients with SoC (72.1% vs. 52.8%, p ≤ 0.001, OR 2.28). Additionally, they expressed higher confidence in their diagnoses for Ls than for SoC (73.9 vs. 61.7, p ≤ 0.001). Therefore, further specialized training seems necessary to improve clinical care of dermatologic patients with SoC.

Background/Aims: It was aimed to investigate the biochemical and histopathological effects of resveratrol and melatonin, via histone H4 and β-defensin 1, in diabetic rats. Materials and Methods: Twenty-four Sprague–Dawley male rats were categorized into 4 groups, with 6 rats in each group (control, diabetes mellitus, melatonin – diabetes mellitus, and resveratrol+diabetes mellitus). Diabetes was formed by giving streptozotocin to all groups except the control group. Melatonin, 5 mg/kg/day, was given to the melatonin – diabetes mellitus group, and resveratrol, 5 mg/kg/day, was given to the resveratrol+diabetes mellitus group via intraperitoneally for 3 weeks. Interleukin-1 beta, tumor necrosis factor alpha, histone H4, and β-defensin 1 levels were measured in the blood of all rats. The lung, liver, and kidney tissue of all rats were performed as histopathological examinations. Results: Whereas there was no difference between the other groups (P > .05), interleukin-1 beta levels of the diabetes mellitus group were found to be significantly higher compared with the control group (5.02 ± 2.15 vs. 2.38 ± 0.72 ng/mL; P < .05). Whereas histone H4 levels of the diabetes mellitus group were higher compared with the control and resveratrol+diabetes mellitus groups (7.53 ± 3.30 vs. 2.97 ± 1.57 and 3.06 ± 1.57 ng/mL; P < .05), the β-defensin 1 levels of the diabetes mellitus group were lower compared with control and resveratrol+diabetes mellitus groups (7.6 ± 2.8 vs. 21.6 ± 5.5 and 18.8 ± 7.4 ng/mL; P < .05). β-Defensin 1 levels were moderately inversely correlated with interleukin-1 beta and histone H4 levels (rs > −0.50, P < .01). Histopathological changes found in favor of target cell damage in the diabetes mellitus group were not observed in resveratrol+diabetes mellitus group. Conclusion: Resveratrol may be used as a biotherapeutic agent, which significantly reduces diabetes-induced histone H4 and interleukin-1 beta-mediated liver and other target organ damage

The purpose of this research is to determine the effect of the Understand-Answer Strategy on the reading comprehension skills of students with learning disabilities. The research was carried out on students with a diagnosis of learning disability studying in secondary schools in Pendik, Istanbul, affiliated with the Ministry of National Education. The selected students are between the ages of 12 and 13, with two girls and one boy. The research was carried out with a single-subject design, a " multiple baseline across subjects model". The research findings have shown that the Understand-Answer Strategy is effective in improving the reading comprehension skills of students with learning difficulties. Furthermore, students who learned this strategy were able to provide correct answers to reading comprehension questions 1, 3, and 5 weeks after the end of the application, and it was observed that students who learned the strategy with different participants generalized their reading comprehension performance. According to the social validity findings, students and their families expressed positive views about the Understand-Answer Strategy.

The aim of this study was to assess the domain-general CT skills of 8th grade students in Turkey. In the study, first, the domain-general CT scale was adapted to Turkish, and then relations of the CT skills with gender, computer possession, internet access, and programming experience were examined. This survey research was conducted with the 284 eighth grade students. The data were analyzed through confirmatory factor analysis, independent sample t-test and Pearson correlation test. The results of the confirmatory factor analysis and Cronbach alpha showed that the Turkish version of the domain-general CT scale was valid and reliable. T-test results showed no significant difference in the CT skills of the students according to gender, computer possession and internet access. A statistically significant difference in algorithm, evaluation, generalization, and general CT skills was found between students who learned programming and those who did not. Correlational tests revealed that there was a positive and significant relationship between the programming experience of students who learn programming and their CT skills. As students' programming experience increased, their CT skills also increased. The results of the research were discussed, and recommendations for policy-makers and implementers were included.

The purpose of this study was to test the validity and reliability of Turkish version of the 21st century skills-oriented TPACK scale, developed by Valtonen et al., (2017). The participants of the study selected with using the convenient sampling included 339 pre-service teachers who enrolled in the teacher education faculty of a state university located in the western part of Turkey. Confirmatory factor analysis was performed for the construct validity of the scale, and Rasch analysis for its validity and reliability. Rasch person and item reliability coefficients for the TPACK were around 0.90. Rasch analysis showed that infit and outfit mean values were in the acceptable fit range. In addition, correlations between the factors showed a strong relation in the theoretical model, indicating a good construct validity. Also, all dimensions of the scale were significantly related to teaching self-efficacy of preservice teachers. Examination pre-service teachers' responses, it was found that they believed that they had adequate knowledge at content and pedagogic matters, but their knowledge at technology and integrating it with pedagogic and context knowledge were at satisfactory level. Educational implications and future directions were discussed.

This study aims to determine mothers' concerns regarding their children, before and after giving birth. The study sample consists of 13 mothers working as special education teachers having graduated from the Special Teaching Department. The study utilized a semi-structured interview technique, which is one of the qualitative research methods, and a content analysis was used to analyze the study data at hand. Study findings revealed that the mothers had some anxieties regarding their children or children they may have in the future due to their occupation, and special education courses they attended during their preservice education. As expectant mothers, the main source of their concerns was that their baby might be born with some health issue or disability. The study findings also revealed that the mothers' concerns began when they found out about their pregnancy, concern continued throughout their pregnancy.

Abstract It was aimed to evaluate long non-coding RNAs (lncRNAs) in terms of diagnosis and prognosis in colorectal cancer (CRC) cases with peritoneal metastasis who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Paraffinized 32 CRC tissue and 32 adjacent normal colon tissue of 32 cases, and paraffinized metastatic 10 peritoneal tumor tissue and 10 adjacent normal peritoneal tissues of 10 cases were included in. Expression levels of lncRNAs GAS5, MALAT1, CCAT2, HOTAIR and H19 were measured by qRT-PCR, clinicopathological and demographic characteristics of the patients were also recorded. 11 (34%) patients were female and 21 (66%) were male. The mean age was 54.59±11.97 (24-73 years). Expression levels of GAS5 decreased significantly in colon tumor tissues compared to normal colon tissues (p