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1. Pediatric cutaneous mucormicosis

Author

Matei, Mariana Claudia, Ramirez, Sandra Castejon, Sanz, Sara Sanz, Cazana, Tamara Gracia, Gomez, Concepcion Lopez, Arnau, Neus Martinez, Alonso, Matilde Bustillo, and Alonso, Isabel Bernad

Subjects
amphotericin B, mucormycosis, necrotic plaques, Rhizopus oryzae
Abstract

A 9-year-old boy diagnosed with acute myeloblastic leukemia and undergoing chemotherapy, was admitted with febrile neutropenia. During his admission, several violaceous plaques appeared on the upper extremities and anterior left hemithorax, which worsened and acquired a necrotic center. We performed a biopsy and histology showed a cutaneous infarction at the dermoepidermal and subcutaneous level. We observed abundant wide hyphae with right-angled branching and a culture isolated Rhizopus oryzae. A plastic surgery consultant performed a surgical debridement of the lesions and treatment was started with intravenous amphotericin B. The patient did well on treatment and after almost a month of hospitalization, he was discharged with oral posaconazole. Mucormycosis is an opportunistic fungal infection associated with immunosuppression, particularly involving prematurity and hematological diseases in the pediatric age group. Multiple lesions, as in our case, are infrequent. The clinical presentation is variable. Direct smear or histological observation is the quickest diagnostic technique whereas culture is the most definitive. The combination of surgical debridement and amphotericin B is the treatment with the highest survival rates.

Published
2023

3. The Value of the Second QuantiFERON-TB Gold-Plus Antigen Tube at Diagnosis and at Treatment Completion in Spanish Children With Tuberculosis

Author

Soler-Garcia, Aleix, Gamell, Anna, Monsonís, Manuel, Korta-Murua, José Javier, Espiau, María, Rincón-López, Elena, Rodríguez-Molino, Paula, Pérez-Porcuna, Tomàs, Bustillo-Alonso, Matilde, Santiago, Begoña, Tebruegge, Marc, Noguera-Julian, Antoni, AZURMENDI-GUNDÍN, Nerea, FORTUNY, Clàudia, COLINO, Elena, GÓMEZ-PASTRANA, David, MONTERO, María, PEROMINGO, Estrella, LAFUENTE-HIDALGO, Miguel, MOLINER, Elisenda, VALMANYA, Teresa, MINGUELL-DOMINGO, Laura, FENOY, Marina, VELÁZQUEZ, Marta, SOLER-CAMPINS, Maria Queralt, GARCIA, Lourdes, LAHOZ, Rebeca, CALAVIA, Olga, PASCUAL, María Teresa, RIUS, Neus, TÓRTOLA, Teresa, SORIANO-ARANDES, Antoni, MARTÍN-NALDA, Andrea, SOLER-PALACÍN, Pere, LILLO, Miguel, DAPENA, Marta, LÓPEZ-MEDINA, Eva María, PIQUERAS, Ana Isabel, RUIZ-JIMÉNEZ, Marta, SOTO-SÁNCHEZ, Beatriz, HERNÁNDEZ, Ángel, RUIZ-SERRANO, María Jesús, COBO-VÁZQUEZ, Elvira, SANTOS, María del Mar, HERNÁNDEZ-SAMPELAYO, Teresa, TAGARRO, Alfredo, MÉNDEZ-ECHEVARRÍA, Ana, MELLADO, María José, BAQUERO-ARTIGAO, Fernando, CALVO, Cristina, SAINZ, Talía, ÁLVAREZ, Javier, GARCÍA ASCASO, Marta Taida, VILLALOBOS, Enrique, PÉREZ-GORRICHO, Beatriz, GARCÍA-GARCÍA, María Luz, GARROTE-LLANOS, Maria Isabel, REMENTERÍA, Joseba, SÁNCHEZ-TORRENT, Laia, GARCÍA-HORTELANO, Milagros, and LOBATO, Zulema

Published
2023
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5. Ventricular Repolarization Parameters and Coronary Involvement in Kawasaki Disease

Author

Fernandez-Cooke, Elisa, Calvo, Cristina, Sánchez-Manubens, Judith, Antón, Jordi, Santos, Javier Aracil, Cuadros, Esmeralda Nuñez, Navarro Gómez, Maria Luisa, Pérez, David Moreno, Cantero Pérez, María Martín, Cuadros Pérez, Esmeralda Nuñez, Gallego Pérez, Begoña Carazo, García, Fernando Sánchez, Lovillo, Marisol Camacho, Marqués, Renata, Laura, Olaf Neth, Silveira, Fernández, Forte, Miguel Sánchez, Montes, Ángeles Ortega, Martínez Campos, Leticia Isabel, Mancheño, Beatriz Bravo, Camacho, Margarita, Medina Claros, Antonio F., Salido, Carlos, Rico, María Torres, Saez, Beatriz Ruiz, de la Puebla Lechuga, Elena Fernadez, Cruz, M<ce:sup loc='post">a</ce:sup> José Lirola, Carrasco, Kety Maya, González, Moisés Rodríguez, Jover, Enrique Blanca, Fernández, José Uberos, Ibáñez Alcalde, María Mercedes, Hidalgo, Miguel Lafuente, Montañés, Lorenzo Jiménez, Alonso, Matilde Bustillo, Casas, Ariadna Ayerza, Zapico, Bárbara Montes, Méndez, Carlos Pérez, Aracama, Javier Fernández, Rodríguez, Lucía, Ibáñez Fernández, María Aleida, Campo, Sandra Navarro, Bori, Silvia Escribà, Mir Perelló, María Concepción, Sánchez, M<ce:sup loc='post">a</ce:sup> Ángeles de la Fuente, García, Patricia Aparicio, Briales, Carlos, Crespí, Joaquín Castilla, Colino Gil, María Elena, Cabrera, Nerea Delgado, Naranjo, Ana Bello, Páez, Jesús Poch, Yáñez, Moneyba García, García, Montse González, Viadero, Maite, Montero, Beatriz Jiménez, García, Olga Domínguez, Pinedo, Begoña Losada, Martín, Gema Iñigo, Escribano Gómez, Lucía María, Cepillo, Antonio, Lillo, Miguel Lillo, Buedo, María Isabel, Rey, Laura del, Rodríguez, Elena Urbaneja, Rodríguez, Sara Rellán, Cantero, Teresa, Izquierdo, Beatriz Plata, García-Cuenllas Álvarez, Luisa, Erroz, Ignacio Oulego, Santaolalla, Elena Pérez, Martín, Carlos Alcalde, Malfaz, Fernando Centeno, Gutiérrez, Elena Pérez, Casso, M<ce:sup loc='post">a</ce:sup> Soledad Jiménez, Prada, Fredy, Bou, Rosa, Iglesias, Estibaliz, Calzada, Joan, Garsaball, Olga Calavia, Rue, Marc Tobeña, García, Gemma Giralt, Lobato, Zulema, Gordillo, Neus Rius, Torres, Montserrat Pascual, Hernández, María Méndez, García, Lourdes, Villar, Sergio Flores, Ruiz, Silvia Yevenes, Domingo, Laura Minguell, Ballester, Anna, Miralles, Ana, Soler, Berta Pujol, Vidal, Anton Foguet, Castellví, Pere Sala, Aguiar, Angelita Serrano, Siurana Rodríguez, José Manuel, Iranzo, Anna Sangorrin, Pérez, Roser Álvarez, Cajas, Paula Ribes, Genaró i Jornet, Pere, Tejada, Ana Grande, Zarallo, Cristina, Martinón-Torres, Federico, Calle, Irene Rivero, Grande, Antonio Justicia, Sousa, María López, Vilas, Alejandro Souto, Abel, Bernardo López, de Miguel Esteban, Elisa, Méndez, Bibiana Riaño, Blázquez, Daniel, Conejo, Pablo Rojo, Lozano, Carlos Grasa, Toral, Belén, De la Torre, Leticia Albert, de Inocencio, Jaime, Santos, Mar, Díaz-Delgado de la Peña, Rafael, Ramos, Paz Collado, Raga, Teresa, Latorre, Libertad, Guillén, Sara, Caballero, Ignacio Callejas, Prieto Tato, Luis Manuel, Guzmán Monagas, María Fernanda, López, Isabel Jiménez, Villagrá, Sandra, Arreo, Viviana, Pérez, Roi Piñeiro, Parte, María de la, Tamariz-Martes, Amalia, Romano, Marta Llorente, Hernández Rupérez, Maria Belén, Sombrero, Henar Rojo, Cerro, Estefanía García, Cano, Irene Maté, Alonso, Marta Villares, Osuna Marco, Marta Pilar, Veron, Julia Jensen, Reales, Cristina Zarallo, Rodríguez Mesa, María Dolores, Esteban, Santiago Rueda, Ramos Amador, José Tomás, Menchén, Cristina González, Jiménez Jiménez, Ana Belén, Galán, Pilar, Campos, Dolores Pérez, Bueno, M<ce:sup loc='post">a</ce:sup> Mercedes, Marcos, David Crespo, Otheo de Tejada Barásoain, Enrique, Sifuentes Giraldo, Walter Alberto, Gámir Gámir, María Luz, José Cilleruelo Ortega, María, López, Agustín López, Vaquerizo, Cristina Sánchez, Usano Carrasco, Ana Isabel, Gómez, Ester Moreno, Carvajal del Castillo, Olga, Del Pozo Menéndez, Beatriz, Navarro, Katie Badillo, Baquero, Fernando, Bronte, Lucía Deiros, Fraga, Pablo Fernández, Domínguez, Nieves, Rodríguez, Beatriz Mercader, García, Francisco Castro, Chamorro, Águeda Herrera, Rodríguez, Paula Alcañiz, García, Moisés Sorlí, Rex Nicolás, María Concepción, Romero, Elena Vera, Olorón, Patricia Martínez, Cilveti, Beatriz Rocandio, Berridi, Amaia, Santos-Díez Vázquez, Laura, Fernández, Olaia, Calvo, Inmaculada, Tudela, Belén Fernández, Benavent, Manuel Oltra, Archilés, Marta Dapena, Ferrer, Franciasco Sanchez, Gavilán, César, Fos, Ignacio Izquierdo, Serrano Robles, María Isabel, Sánchez, Yolanda Herranz, Pinto, Enrique Villalobos, Garulo, Daniel Clemente, Pie, Stella, Calvo, Manuel Marrero, Olmos García, José María, Barrios-Tascón, Ana, Miura, Masaru, Domínguez-Rodríguez, Sara, Fernández-Cooke, Elisa, Sarquella-Brugada, Georgia, and Tagarro, Alfredo

Published
2021
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6. Interferon-Gamma Release Assays Differentiate between Mycobacterium avium Complex and Tuberculous Lymphadenitis in Children

Author

Vallmanya, Teresa, Minguell, Laura, Martín-Nalda, Andrea, Soler-Palacín, Pere, Espiau, María, Lobato, Zulema, Garcia, Lourdes, Velázquez, Marta, Herranz, Mercedes, Arroyo, Mireia, Gutiérrez, Carmelo, Gavilán, César, Piqueras, Ana Isabel, Martinón-Torres, Federico, Villanueva, Isabel, Rueda, Santiago, Ramos, Marta Illán, Morales, Ana, ROA, Miguel, Pérez-Gorricho, Beatriz, Pinto, Enrique Villalobos, Sanz-Santaeufemia, Francisco José, Álvarez, Javier, Álvarez, Cristina, Guarch, Borja, Montero, María, Cilleruelo, María José, Otheo, Enrique, Calvo, Cristina, Korta Murua, José Javier, Mellado, María José, Rojo, Pablo, Moreno-Pérez, David, Neth, Olaf, Santos, Mar, Hernández, Teresa, Hidalgo, Miguel Lafuente, Antonio Cepillo, Martínez-Planas, Aina, Baquero-Artigao, Fernando, Santiago, Begoña, Fortuny, Clàudia, Méndez-Echevarría, Ana, Del Rosal, Teresa, Bustillo-Alonso, Matilde, Gale, Inés, Guerrero, Carmelo, Blázquez-Gamero, Daniel, Canet, Anna, Lillo, Miguel, Calavia, Olga, Núñez Cuadros, Esmeralda, Falcón-Neyra, Lola, Soriano-Arandes, Antoni, Van Ingen, Jakko, Tebruegge, Marc, and Noguera-Julian, Antoni

Published
2021
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7. Evaluation of the impact of the Spanish Consensus Document on the approach to osteoarticular infections in Spain through the Paediatrics Osteoarticular Infections Network (RIOPED)

Author

Rueda, Rosa Alcobendas, Garulo, Daniel Clemente, Santaeufemia, F. José Sanz, Campos, Leticia Martínez, García, Alfredo Tagarro, Fontecha, César G., Melendo-Pérez, Susana, Lovillo, Marisol Camacho, Neyra, Lola Falcón, Cruz, M. José Lirola, Gil, Elena Colino, Carreño, Patricia Tejera, Canals, Luis Mayol, Zarketa, Daniel Domenech, Campaña, M. Mercedes Bueno, Méndez, Carlos Pérez, Gordillo, Neus Rius, Cardona, Verónica, Colom, Jaime Carrasco, Fernández, Antonio Conejo, Ramírez, Marta García, Delgado, Rafael Díez, Ordónez, Carmen Vázquez, Tejada, Enrique Otheo de, Gianzo, José Couceiro, Arranz, Leonor, García-Pardos, Carmen, Piñeiro-Pérez, Roi, Mancheño, Beatriz Bravo, López-Molina, Inmaculada, Acevedo, Adriana Vidal, Antón, María Penín, Coll, M. Teresa, Soler, Berta Pujol, Pérez, Pilar Ranchal, Morales, Sara Pons, Sevilla, Belén, Hernández, María Méndez, García-Mazarío, M. Jesús, Martín, César Gavilán, Fernández-Cooke, Elisa, Canet, Anna, Jiménez, Marta Ruiz, González, Marina, Rodríguez, Lourdes García, Moreno, Carmen, Lizarbe, Miren Oscoz, Martín-Pedraz, Laura, Lillo, Miguel Lillo, Cepillo, Antonio J., Soler-Palacín, Pere, Ramakers, Jan, Gasaball, Olga Calavia, Ramo, Rebeca Lahoz, Barrero, Pedro Terol, Vilchez, M. José Muñoz, Pérez, Victoria Fumadó, Camps, Silvia Urraca, Rodríguez, Elena Urbaneja, Ortega, M. José Cilleruelo, López, Agustín López, Solas, Valentín Pineda, Pedrab, Carla Monterde, Molina, Rosa Roldán, Masegosa-Casanova, Sandra, Rodríguez, Paula Alcañiz, Ruíz, Ana Menasalvas, Arístegui-Fernández, Javier, Garrote, Elisa, Martinón-Torres, Federico, Rivero-Calle, Irene, Ramos, José Tomás, Ramos, Marta Illán, Montero, Beatriz Jiménez, Pinedo, Begoña Losada, Ibáñez, Borja Guarch, Serrano, Marcelina Algar, García, M. Dolores, Pereira, Elena, Rodríguez-Blanco, Silvia, Fontán, Manuel Muñiz, Reyes, Sagrario Bustabab, Claros, Antonio Medina, Oñós, Isabel Vives, Perelló, M. Concepción Mir, Barreiro, Natalia Cerdeira, Barnés, María Ríos, Patudo, Isabel Vara, Martínez-Regueira, Soledad, Domenech, Raquel Marín, Vílchez, Juan Salvador, Moreno, Jesús de la Cruz, Laleona, Carmelo Guerrero, Alonso, Matilde Bustillo, Meléndez, Leticia Merino, Martín, Azucena García, Núñez Cuadros, Esmeralda, Calvo, Cristina, and Saavedra-Lozano, Jesús

Published
2020
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8. Evaluación del impacto del Documento de Consenso español sobre el abordaje de las infecciones osteoarticulares en nuestro medio a través de la Red de Infecciones Osteoarticulares Pediátricas (RIOPed)

Author

Rueda, Rosa Alcobendas, Garulo, Daniel Clemente, Santaeufemia, F. José Sanz, Campos, Leticia Martínez, García, Alfredo Tagarro, Fontecha, César G., Melendo-Pérez, Susana, Lovillo, Marisol Camacho, Neyra, Lola Falcón, Cruz, M. José Lirola, Gil, Elena Colino, Carreño, Patricia Tejera, Canals, Luis Mayol, Zarketa, Daniel Domenech, Campaña, M. Mercedes Bueno, Méndez, Carlos Pérez, Gordillo, Neus Rius, Cardona, Verónica, Colom, Jaime Carrasco, Fernández, Antonio Conejo, Ramírez, Marta García, Delgado, Rafael Díez, Ordónez, Carmen Vázquez, Tejada, Enrique Otheo de, Gianzo, José Couceiro, Arranz, Leonor, García-Pardos, Carmen, Piñeiro-Pérez, Roi, Mancheño, Beatriz Bravo, López-Molina, Inmaculada, Acevedo, Adriana Vidal, Antón, María Penín, Coll, M. Teresa, Soler, Berta Pujol, Pérez, Pilar Ranchal, Morales, Sara Pons, Sevilla, Belén, Hernández, María Méndez, García-Mazarío, M. Jesús, Martín, César Gavilán, Fernández-Cooke, Elisa, Canet, Anna, Jiménez, Marta Ruiz, González, Marina, Rodríguez, Lourdes García, Moreno, Carmen, Lizarbe, Miren Oscoz, Martín-Pedraz, Laura, Lillo, Miguel Lillo, Cepillo, Antonio J., Soler-Palacín, Pere, Ramakers, Jan, Gasaball, Olga Calavia, Ramo, Rebeca Lahoz, Barrero, Pedro Terol, Vilchez, M. José Muñoz, Pérez, Victoria Fumadó, Camps, Silvia Urraca, Rodríguez, Elena Urbaneja, Ortega, M. José Cilleruelo, López, Agustín López, Solas, Valentín Pineda, Pedrab, Carla Monterde, Molina, Rosa Roldán, Masegosa-Casanova, Sandra, Rodríguez, Paula Alcañiz, Ruíz, Ana Menasalvas, Arístegui-Fernández, Javier, Garrote, Elisa, Martinón-Torres, Federico, Rivero-Calle, Irene, Ramos, José Tomás, Ramos, Marta Illán, Montero, Beatriz Jiménez, Pinedo, Begoña Losada, Ibáñez, Borja Guarch, Serrano, Marcelina Algar, García, M. Dolores, Pereira, Elena, Rodríguez-Blanco, Silvia, Fontán, Manuel Muñiz, Reyes, Sagrario Bustabab, Claros, Antonio Medina, Oñós, Isabel Vives, Perelló, M. Concepción Mir, Barreiro, Natalia Cerdeira, Barnés, María Ríos, Patudo, Isabel Vara, Martínez-Regueira, Soledad, Domenech, Raquel Marín, Vílchez, Juan Salvador, Moreno, Jesús de la Cruz, Laleona, Carmelo Guerrero, Alonso, Matilde Bustillo, Meléndez, Leticia Merino, Martín, Azucena García, Núñez Cuadros, Esmeralda, Calvo Rey, Cristina, and Saavedra-Lozano, Jesús

Published
2020
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10. Pediatric cutaneous mucormicosis

Author

Matei, Mariana Claudia, primary, Ramirez, Sandra Castejon, additional, Sanz, Sara Sanz, additional, Cazana, Tamara Gracia, additional, Gomez, Concepcion Lopez, additional, Arnau, Neus Martinez, additional, Alonso, Matilde Bustillo, additional, and Alonso, Isabel Bernad, additional

Published
2024
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15. Contributors

Author

Aguilar, María Rosa, primary, Alonso, Matilde, additional, Asha, Anika B., additional, Berges, C., additional, Blasco, E., additional, Cabello, José Carlos Rodríguez, additional, Carretero-González, Javier, additional, Corrales, Rocío, additional, Cui, J., additional, Custódio, Catarina A., additional, de Torre, Israel Gonzalez, additional, del Agua, Isabel, additional, del Campo, Aránzazu, additional, den Brabander, Michael, additional, Duro-Castano, A., additional, Espinosa-Cano, Eva, additional, Fischer, Hartmut R., additional, Galaev, I.Y., additional, Garcia, Santiago J., additional, García, Félix C., additional, García, José Miguel, additional, García-Arévalo, Carmen, additional, García-Fernández, Luis, additional, Gómez-Mascaraque, L.G., additional, Hao, Xiaojuan, additional, Hasirci, Nesrin, additional, Hoogenboom, Richard, additional, Jorcano, José Luis, additional, López-Manchado, Miguel Angel, additional, Malikmammadov, Elbay, additional, Malliaras, George G., additional, Mano, João F., additional, Mecerreyes, David, additional, Mikhalovsky, S.V., additional, Montero, Andrés, additional, Montero, Jorge, additional, Mora-Boza, Ana, additional, Narain, Ravin, additional, Oriol, L., additional, Palao-Suay, R., additional, Piñol, M., additional, Reglero Ruiz, José A., additional, Reis, Rui L., additional, Reyes-Ortega, Felisa, additional, Rodríguez-Escalona, G., additional, Román, Julio San, additional, Sanchez-Sanchez, Ana, additional, Sánchez-Somolinos, C., additional, Sanjuán, Ana M., additional, Savina, I.N., additional, Srinivas, Shruti, additional, Talelli, M., additional, Valencia, Leticia, additional, Vázquez, Blanca, additional, Velasco, Diego, additional, Vicent, M.J., additional, and Xiong, X., additional

Published
2019
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18. Transient Viral Rebound in Children with Perinatally Acquired HIV-1 Induces a Unique Soluble Immunometabolic Signature Associated with Decreased CD4/CD8 Ratio

Author

Tarancon-Diez, Laura, primary, Peraire, Joaquim, additional, Jiménez de Ory, Santiago, additional, Guirro, Maria, additional, Escosa, Luis, additional, Prieto Tato, Luis Manuel, additional, Penín Antón, María, additional, Piqueras, Ana Isabel, additional, Vázquez Pérez, Álvaro, additional, Gavilán, César, additional, Bustillo-Alonso, Matilde, additional, Navarro, María Luisa, additional, Viladés, Consuelo, additional, Vidal, Francesc, additional, Rull, Anna, additional, and Muñoz-Fernández, María Ángeles, additional

Published
2023
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23. Performance of QuantiFERON-TB Gold Plus assays in paediatric tuberculosis: a multicentre PTBNET study

Author

Buonsenso, Danilo, primary, Noguera-Julian, Antoni, additional, Moroni, Rossana, additional, Hernández-Bartolomé, Angel, additional, Fritschi, Nora, additional, Lancella, Laura, additional, Cursi, Laura, additional, Soler-Garcia, Aleix, additional, Krüger, Renate, additional, Feiterna-Sperling, Cornelia, additional, Sali, Michela, additional, Lo Vecchio, Andrea, additional, Scarano, Sara, additional, Hernanz Lobo, Alicia, additional, Espiau, Maria, additional, Soriano-Arandes, Antonio, additional, Cetin, Benhur Sirvan, additional, Brinkmann, Folke, additional, Ozere, Iveta, additional, Baquero-Artigao, Fernando, additional, Tsolia, Maria, additional, Milheiro Silva, Tiago, additional, Bustillo-Alonso, Matilde, additional, Martín Nalda, Andrea, additional, Mancini, Margherita, additional, Starshinova, Anna, additional, Ritz, Nicole, additional, Velizarova, Svetlana, additional, Ferreras-Antolín, Laura, additional, Götzinger, Florian, additional, Bilogortseva, Olga, additional, Chechenyeva, Vira, additional, Tebruegge, Marc, additional, and Santiago-García, Begoña, additional

Published
2022
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29. Mesenchymal Stromal Cells Combined With Elastin-Like Recombinamers Increase Angiogenesis In Vivo After Hindlimb Ischemia

Author

Ibáñez-Fonseca, Arturo, primary, Rico, Ana, additional, Preciado, Silvia, additional, González-Pérez, Fernando, additional, Muntión, Sandra, additional, García-Briñón, Jesús, additional, García-Macías, María-Carmen, additional, Rodríguez-Cabello, José Carlos, additional, Pericacho, Miguel, additional, Alonso, Matilde, additional, and Sánchez-Guijo, Fermín, additional

Published
2022
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37. Performance of QuantiFERON-TB Gold Plus assays in children and adolescents at risk of tuberculosis: a cross-sectional multicentre study

Author

Soler-Garcia, Aleix, primary, Gamell, Anna, additional, Pérez-Porcuna, Tomàs, additional, Soriano-Arandes, Antonio, additional, Santiago, Begoña, additional, Tórtola, Teresa, additional, Ruiz-Serrano, María Jesús, additional, Korta Murua, José Javier, additional, Bustillo-Alonso, Matilde, additional, Garrote-Llanos, María Isabel, additional, Rodríguez-Molino, Paula, additional, Piqueras, Ana Isabel, additional, Tagarro, Alfredo, additional, Monsonís, Manuel, additional, Tebruegge, Marc, additional, and Noguera-Julian, Antoni, additional

Published
2021
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38. Performance of QuantiFERON- Gold Plus assays in children and adolescents at risk of tuberculosis: a cross-sectional multicentre study.

Author

Soler-Garcia, Aleix, Gamell, Anna, Pérez-Porcuna, Tomàs, Soriano-Arandes, Antonio, Santiago, Begoña, Tórtola, Teresa, Jesús Ruiz-Serrano, María, Korta Murua, José Javier, Bustillo-Alonso, Matilde, Isabel Garrote-Llanos, María, Rodríguez-Molino, Paula, Isabel Piqueras, Ana, Tagarro, Alfredo, Monsonís, Manuel, Tebruegge, Marc, Noguera-Julian, Antoni, Ruiz-Serrano, María Jesús, Garrote-Llanos, María Isabel, Piqueras, Ana Isabel, and QFT-Plus Study Group of the Spanish Pediatric TB Research Network

Subjects
LATENT tuberculosis, LYMPHADENITIS, TUBERCULOSIS, NEUROBLASTOMA, MYCOBACTERIAL diseases, LATENT infection, TEENAGERS, TUBERCULOSIS diagnosis, CROSS-sectional method, INTERFERON gamma release tests, EVALUATION research, TUBERCULIN test, RESEARCH, COMPARATIVE studies, MYCOBACTERIUM tuberculosis
Abstract

Introduction: The QuantiFERON-TB Gold Plus (QFT-Plus) assay, which features two antigen-stimulated tubes (TB1 and TB2) instead of a single tube used in previous-generation interferon-gamma release assays (IGRAs), was launched in 2016. Despite this, data regarding the assay's performance in the paediatric setting remain scarce. This study aimed to determine the performance of QFT-Plus in a large cohort of children and adolescents at risk of tuberculosis (TB) in a low-burden setting.Methods: Cross-sectional, multicentre study at healthcare institutions participating in the Spanish Paediatric TB Research Network, including patients <18 years who had a QFT-Plus performed between September 2016 and June 2020.Results: Of 1726 patients (52.8% male, median age: 8.4 years), 260 (15.1%) underwent testing during contact tracing, 288 (16.7%) on clinical/radiological suspicion of tuberculosis disease (TBD), 649 (37.6%) during new-entrant migrant screening and 529 (30.6%) prior to initiation of immunosuppressive treatment. Overall, the sensitivity of QFT-Plus for TBD (n=189) and for latent tuberculosis infection (LTBI, n=195) was 83.6% and 68.2%, respectively. The agreement between QFT-Plus TB1 and TB2 antigen tubes was excellent (98.9%, κ=0.961). Only five (2.5%) patients with TBD had discordance between TB1 and TB2 results (TB1+/TB2-, n=2; TB1-/TB2+, n=3). Indeterminate assay results (n=54, 3.1%) were associated with young age, lymphopenia and elevated C reactive protein concentrations.Conclusions: Our non-comparative study indicates that QFT-Plus does not have greater sensitivity than previous-generation IGRAs in children in both TBD and LTBI. In TBD, the addition of the second antigen tube, TB2, does not enhance the assay's performance substantially. [ABSTRACT FROM AUTHOR]

Published
2022
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41. Ventricular Repolarization Parameters and Coronary Involvement in Kawasaki Disease

Author

Barrios-Tascón, Ana, primary, Miura, Masaru, additional, Domínguez-Rodríguez, Sara, additional, Fernández-Cooke, Elisa, additional, Sarquella-Brugada, Georgia, additional, Tagarro, Alfredo, additional, Fernandez-Cooke, Elisa, additional, Calvo, Cristina, additional, Sánchez-Manubens, Judith, additional, Antón, Jordi, additional, Santos, Javier Aracil, additional, Cuadros, Esmeralda Nuñez, additional, Navarro Gómez, Maria Luisa, additional, Pérez, David Moreno, additional, Cantero Pérez, María Martín, additional, Cuadros Pérez, Esmeralda Nuñez, additional, Gallego Pérez, Begoña Carazo, additional, García, Fernando Sánchez, additional, Lovillo, Marisol Camacho, additional, Marqués, Renata, additional, Laura, Olaf Neth, additional, Silveira, Fernández, additional, Forte, Miguel Sánchez, additional, Montes, Ángeles Ortega, additional, Martínez Campos, Leticia Isabel, additional, Mancheño, Beatriz Bravo, additional, Camacho, Margarita, additional, Medina Claros, Antonio F., additional, Salido, Carlos, additional, Rico, María Torres, additional, Saez, Beatriz Ruiz, additional, de la Puebla Lechuga, Elena Fernadez, additional, Cruz, Ma José Lirola, additional, Carrasco, Kety Maya, additional, González, Moisés Rodríguez, additional, Jover, Enrique Blanca, additional, Fernández, José Uberos, additional, Ibáñez Alcalde, María Mercedes, additional, Hidalgo, Miguel Lafuente, additional, Montañés, Lorenzo Jiménez, additional, Alonso, Matilde Bustillo, additional, Casas, Ariadna Ayerza, additional, Zapico, Bárbara Montes, additional, Méndez, Carlos Pérez, additional, Aracama, Javier Fernández, additional, Rodríguez, Lucía, additional, Ibáñez Fernández, María Aleida, additional, Campo, Sandra Navarro, additional, Bori, Silvia Escribà, additional, Mir Perelló, María Concepción, additional, Sánchez, Ma Ángeles de la Fuente, additional, García, Patricia Aparicio, additional, Briales, Carlos, additional, Crespí, Joaquín Castilla, additional, Colino Gil, María Elena, additional, Cabrera, Nerea Delgado, additional, Naranjo, Ana Bello, additional, Páez, Jesús Poch, additional, Yáñez, Moneyba García, additional, García, Montse González, additional, Viadero, Maite, additional, Montero, Beatriz Jiménez, additional, García, Olga Domínguez, additional, Pinedo, Begoña Losada, additional, Martín, Gema Iñigo, additional, Escribano Gómez, Lucía María, additional, Cepillo, Antonio, additional, Lillo, Miguel Lillo, additional, Buedo, María Isabel, additional, Rey, Laura del, additional, Rodríguez, Elena Urbaneja, additional, Rodríguez, Sara Rellán, additional, Cantero, Teresa, additional, Izquierdo, Beatriz Plata, additional, García-Cuenllas Álvarez, Luisa, additional, Erroz, Ignacio Oulego, additional, Santaolalla, Elena Pérez, additional, Martín, Carlos Alcalde, additional, Malfaz, Fernando Centeno, additional, Gutiérrez, Elena Pérez, additional, Casso, Ma Soledad Jiménez, additional, Prada, Fredy, additional, Bou, Rosa, additional, Iglesias, Estibaliz, additional, Calzada, Joan, additional, Garsaball, Olga Calavia, additional, Rue, Marc Tobeña, additional, García, Gemma Giralt, additional, Lobato, Zulema, additional, Gordillo, Neus Rius, additional, Torres, Montserrat Pascual, additional, Hernández, María Méndez, additional, García, Lourdes, additional, Villar, Sergio Flores, additional, Ruiz, Silvia Yevenes, additional, Domingo, Laura Minguell, additional, Ballester, Anna, additional, Miralles, Ana, additional, Soler, Berta Pujol, additional, Vidal, Anton Foguet, additional, Castellví, Pere Sala, additional, Aguiar, Angelita Serrano, additional, Siurana Rodríguez, José Manuel, additional, Iranzo, Anna Sangorrin, additional, Pérez, Roser Álvarez, additional, Cajas, Paula Ribes, additional, Genaró i Jornet, Pere, additional, Tejada, Ana Grande, additional, Zarallo, Cristina, additional, Martinón-Torres, Federico, additional, Calle, Irene Rivero, additional, Grande, Antonio Justicia, additional, Sousa, María López, additional, Vilas, Alejandro Souto, additional, Abel, Bernardo López, additional, de Miguel Esteban, Elisa, additional, Méndez, Bibiana Riaño, additional, Blázquez, Daniel, additional, Conejo, Pablo Rojo, additional, Lozano, Carlos Grasa, additional, Toral, Belén, additional, De la Torre, Leticia Albert, additional, de Inocencio, Jaime, additional, Santos, Mar, additional, Díaz-Delgado de la Peña, Rafael, additional, Ramos, Paz Collado, additional, Raga, Teresa, additional, Latorre, Libertad, additional, Guillén, Sara, additional, Caballero, Ignacio Callejas, additional, Prieto Tato, Luis Manuel, additional, Guzmán Monagas, María Fernanda, additional, López, Isabel Jiménez, additional, Villagrá, Sandra, additional, Arreo, Viviana, additional, Pérez, Roi Piñeiro, additional, Parte, María de la, additional, Tamariz-Martes, Amalia, additional, Romano, Marta Llorente, additional, Hernández Rupérez, Maria Belén, additional, Sombrero, Henar Rojo, additional, Cerro, Estefanía García, additional, Cano, Irene Maté, additional, Alonso, Marta Villares, additional, Osuna Marco, Marta Pilar, additional, Veron, Julia Jensen, additional, Reales, Cristina Zarallo, additional, Rodríguez Mesa, María Dolores, additional, Esteban, Santiago Rueda, additional, Ramos Amador, José Tomás, additional, Menchén, Cristina González, additional, Jiménez Jiménez, Ana Belén, additional, Galán, Pilar, additional, Campos, Dolores Pérez, additional, Bueno, Ma Mercedes, additional, Marcos, David Crespo, additional, Otheo de Tejada Barásoain, Enrique, additional, Sifuentes Giraldo, Walter Alberto, additional, Gámir Gámir, María Luz, additional, José Cilleruelo Ortega, María, additional, López, Agustín López, additional, Vaquerizo, Cristina Sánchez, additional, Usano Carrasco, Ana Isabel, additional, Gómez, Ester Moreno, additional, Carvajal del Castillo, Olga, additional, Del Pozo Menéndez, Beatriz, additional, Navarro, Katie Badillo, additional, Baquero, Fernando, additional, Bronte, Lucía Deiros, additional, Fraga, Pablo Fernández, additional, Domínguez, Nieves, additional, Rodríguez, Beatriz Mercader, additional, García, Francisco Castro, additional, Chamorro, Águeda Herrera, additional, Rodríguez, Paula Alcañiz, additional, García, Moisés Sorlí, additional, Rex Nicolás, María Concepción, additional, Romero, Elena Vera, additional, Olorón, Patricia Martínez, additional, Cilveti, Beatriz Rocandio, additional, Berridi, Amaia, additional, Santos-Díez Vázquez, Laura, additional, Fernández, Olaia, additional, Calvo, Inmaculada, additional, Tudela, Belén Fernández, additional, Benavent, Manuel Oltra, additional, Archilés, Marta Dapena, additional, Ferrer, Franciasco Sanchez, additional, Gavilán, César, additional, Fos, Ignacio Izquierdo, additional, Serrano Robles, María Isabel, additional, Sánchez, Yolanda Herranz, additional, Pinto, Enrique Villalobos, additional, Garulo, Daniel Clemente, additional, Pie, Stella, additional, Calvo, Manuel Marrero, additional, and Olmos García, José María, additional

Published
2021
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44. QuantiFERON-TB Gold Plus Assay Specificity in Children and Adolescents With Suspected Tuberculosis—A Multicenter Cross-sectional Study in Spain

Author

Soler-Garcia, Aleix, primary, Gamell, Anna, additional, Santiago, Begoña, additional, Monsonís, Manuel, additional, Cobo-Vázquez, Elvira, additional, Bustillo-Alonso, Matilde, additional, Tagarro, Alfredo, additional, Pérez-Gorricho, Beatriz, additional, Espiau, María, additional, Piqueras, Ana Isabel, additional, Korta-Murua, José Javier, additional, Rodríguez-Molino, Paula, additional, Lobato, Zulema, additional, Pérez-Porcuna, Tomàs, additional, Tebruegge, Marc, additional, and Noguera-Julian, Antoni, additional

Published
2021
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45. Abordajes jurídico-forenses ante las violencias. Perspectivas de intervención en los complejos escenarios actuales ; Forensic legal approaches to violence. Intervention perspectives in today´s complex scenarios

Author

Alonso, Matilde and Alonso, Matilde

Abstract

En el marco del postgrado Especialización en Problemáticas Subjetivas del Contexto Jurídico Forense, dictado en la Universidad Católica de Salta en el año 2017, presenté algunas reflexiones que aquí se actualizan, atendiendo a los complejos escenarios en los que, bajo diversas modalidades, se efectúan abordajes relacionados con las violencias en la provincia de Salta. Frente a los diferentes contextos sobre «las violencias» —familiar, de género, maltrato y abuso sexual infantojuvenil, maltrato y abuso a personas mayores, violación de derechos a personas con capacidades restringidas—, las y los operadores del sistema de administración de justicia y quienes integran el escenario jurídico forense son los que desarrollan sus funciones desde diversas instituciones y disciplinas convocadas..., Fil: Alonso, Matilde. Universidad Católica de Salta. Facultad de Artes y Ciencias; Argentina.

Published
2021

46. Repercusiones de Informes Psicológicos de víctimas de abuso sexual en sentencias judiciales entre 2015 y 2019

Author

Alonso, Matilde, Perez, María de los Angeles, Alonso, Matilde, and Perez, María de los Angeles

Abstract

Se expone una investigación cualitativa de tipo exploratoria, correlacional y descriptiva acerca de versiones que asume la encrucijada entre lo jurídico/judicial y las prácticas psi (Psicología, Psicoanálisis), a través de las repercusiones de Informes psicológicos en los enunciados de las sentencias judiciales; en tanto entramado de relatos, intertextualidad. Compleja red de discursos del poder y del saber cristalizados en las instituciones (Camargo, 1996) del contexto jurídico forense como en su dimensión de “prácticas discursivas actuales que tienden a producir efectos de sentido” (Calmels, 2015, pág. 122). Se acotó la injerencia a Informes Psicológicos de víctimas de abuso sexual expedidos por la autora entre 2015 y 2019 (en trabajo conjunto con Fiscalías Penales del Ministerio Público provincial) y las Sentencias Judiciales vinculadas, en el Distrito Judicial Orán - Salta, Argentina. Se analizaron cinco sentencias, una por año, resultantes de muestra probabilística. No obstante los marcos procesales que encuadran el trabajo conjunto, la relación entre lo jurídico/judicial y las prácticas psi, asume distintas versiones en el quehacer concreto. Suscitan repercusiones, efectos de sentido a menudo inadvertidos, arraigados, repetidos; que impactan sobre la posibilidad de escucha y de trabajo conjunto, sobre la índole de demandas, sobre las consideraciones de eficacia o no de las prácticas, sobre la comprensión y el empleo de respuestas y sugerencias, sobre el provecho o no que se recoja de intervenciones, sobre la calidad de atención y respuesta a los usuarios, sobre las elaboraciones de hechos traumáticos, sobre el imaginario social y las ficciones de la época, sobre el real acceso a justicia y la satisfacción mutua o no en el trabajo conjunto. Se parte de la premisa de la relevante relación entre las representaciones acerca del saber psi y de sus prácticas específicas y las repercusiones que puedan tener o no los dictámenes psicológicos en la toma de decisiones ju, Fil: Alonso, Matilde. Universidad Católica de Salta. Facultad de Artes y Ciencias; Argentina., Fil: Perez, María de los Angeles. Universidad Católica de Salta. Facultad de Artes y Ciencias; Argentina.

Published
2021

47. Performance of QuantiFERON-TB Gold Plus assays in paediatric tuberculosis: a multicentre PTBNET study

Author

Buonsenso, Danilo, Noguera-Julian, Antoni, Moroni, Rossana, Hernández-Bartolomé, Angel, Fritschi, Nora, Lancella, Laura, Cursi, Laura, Soler-Garcia, Aleix, Kru¨ger, Renate, Feiterna-Sperling, Cornelia, Sali, Michela, Lo Vecchio, Andrea, Scarano, Sara, Hernanz Lobo, Alicia, Espiau, Maria, Soriano-Arandes, Antonio, Cetin, Benhur Sirvan, Brinkmann, Folke, Ozere, Iveta, Baquero-Artigao, Fernando, Tsolia, Maria, Milheiro Silva, Tiago, Bustillo-Alonso, Matilde, Martín Nalda, Andrea, Mancini, Margherita, Starshinova, Anna, Ritz, Nicole, Velizarova, Svetlana, Ferreras-Antolín, Laura, Go¨tzinger, Florian, Bilogortseva, Olga, Chechenyeva, Vira, Tebruegge, Marc, and Santiago-García, Begoña

Abstract

RationaleIn 2016, a new interferon-gamma release assay (IGRA) was introduced, QuantiFERON-TB Gold Plus (QFT-Plus), claimed to have improved sensitivity in active tuberculosis (TB).ObjectivesThis study aimed to determine the performance of QFT-Plus, compared with previous generation IGRAs and the tuberculin skin test (TST), in children with TB in Europe.MethodsMulticentre, ambispective cohort study within the Paediatric Tuberculosis Network European Trials Group (ptbnet), a dedicated paediatric TB research network comprising >300 members, capturing TB cases <18 years-of-age diagnosed between January 2009 and December 2019.Measurements and main results1001 TB cases from 16 countries were included (mean age (IQR) 5.6 (2.4–12.1) years). QFT-Plus was performed in 358, QFT Gold in-Tube (QFT-GIT) in 600, T-SPOT.TBin 58 and TST in 636 cases. The overall test sensitivities were: QFT-Plus 83.8% (95% CI 80.2% to 87.8%), QFT-GIT 85.5% (95% CI 82.7% to 88.3%), T-SPOT.TB77.6% (95% CI 66.9% to 88.3%) and TST (cut-off ≥10 mm) 83.3% (95% CI 83.3% to 86.2%). There was a trend for tests to have lower sensitivity in patients with miliary and/or central nervous system (CNS) TB (73.1%, 70.9%, 63.6% and 43.5%, respectively), and in immunocompromised patients (75.0%, 59.6%, 45.5% and 59.1%, respectively).ConclusionsThe results indicate that the latest generation IGRA assay, QFT-Plus, does not perform better than previous generation IGRAs or the TST in children with TB disease. Overall, tests performed worse in CNS and miliary TB, and in immunocompromised children. None of the tests evaluated had sufficiently high sensitivity to be used as a rule-out test in children with suspected TB.

Published
2023
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49. Síndrome de shock tóxico estreptocócico

Author

Gutiérrez Sánchez, Aída Mª, López Rojo, Myriam, Guerrero Laleona, Carmelo, and Bustillo Alonso, Matilde

Subjects
Streptococcus pyogenes, Shock tóxico estreptocócico, Streptococcal toxic shock
Abstract

Resumen El síndrome de shock tóxico estreptocócico (SSTS) es un cuadro grave e infrecuente en Pediatría. Sin embargo, en las últimas décadas está aumentando la incidencia de infecciones invasivas por Streptococcus pyogenes o estreptococo del grupo A. Aparece más frecuentemente en niños preescolares, ya que el diagnóstico de enfermedad estreptocócica es más complicado a esta edad. Es fundamental el diagnóstico y tratamiento precoz debido a su potencial gravedad, precisando en algunas ocasiones medidas intensivas de soporte vital y prevención del fallo multiorgánico. Abstract Streptococcal toxic shock syndrome (STSS) is a serious and uncommon disease in Pediatrics. However, in the last decades the incidence of invasive infections by Streptococcus pyogenes of group A streptococcus has increased. It appears more frequently in preschool children since the diagnosis of streptococcal disease is more complicated at this age. Early diagnosis and treatment are essential due to its potential severity, sometimes requiring intensive life support measures and prevention of multiorgan failure.

Published
2020

50. Síndrome de shock tóxico estreptocócico

Author

Gutiérrez Sánchez,Aída Mª, López Rojo,Myriam, Guerrero Laleona,Carmelo, and Bustillo Alonso,Matilde

Subjects
Streptococcus pyogenes, Shock tóxico estreptocócico
Abstract

Resumen El síndrome de shock tóxico estreptocócico (SSTS) es un cuadro grave e infrecuente en Pediatría. Sin embargo, en las últimas décadas está aumentando la incidencia de infecciones invasivas por Streptococcus pyogenes o estreptococo del grupo A. Aparece más frecuentemente en niños preescolares, ya que el diagnóstico de enfermedad estreptocócica es más complicado a esta edad. Es fundamental el diagnóstico y tratamiento precoz debido a su potencial gravedad, precisando en algunas ocasiones medidas intensivas de soporte vital y prevención del fallo multiorgánico.

Published
2020

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