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1. Repetitive ambulatory levosimendan as a bridge to heart transplantation

Author

de Juan Bagudá, Javier, de Frutos, Fernando, López-Vilella, Raquel, Couto Mallón, David, Guzman-Bofarull, Joan, Blazquez-Bermejo, Zorba, Cobo-Belaustegui, Manuel, Mitroi, Cristina, Pastor-Pérez, Francisco J., Moliner-Abós, Carlos, Rangel-Sousa, Diego, Díaz-Molina, Beatriz, Tobar-Ruiz, Javier, Salterain Gonzalez, Nahikari, García-Pinilla, José Manuel, García-Cosío Carmena, María Dolores, Crespo-Leiro, María Generosa, Dobarro, David, Almenar, Luis, Delgado-Jiménez, Juan F., Paredes-Galán, Emilio, González-Vílchez, Francisco, and González-Costello, José

Published
2024
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2. Levosimendán ambulatorio repetitivo como puente al trasplante cardiaco

Author

de Juan Bagudá, Javier, de Frutos, Fernando, López-Vilella, Raquel, Couto Mallón, David, Guzman-Bofarull, Joan, Blazquez-Bermejo, Zorba, Cobo-Belaustegui, Manuel, Mitroi, Cristina, Pastor-Pérez, Francisco J., Moliner-Abós, Carlos, Rangel-Sousa, Diego, Díaz-Molina, Beatriz, Tobar-Ruiz, Javier, Salterain Gonzalez, Nahikari, García-Pinilla, José Manuel, García-Cosío Carmena, María Dolores, Crespo-Leiro, María Generosa, Dobarro, David, Almenar, Luis, Delgado-Jiménez, Juan F., Paredes-Galán, Emilio, González-Vílchez, Francisco, and González-Costello, José

Published
2024
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6. Validation of the usefulness of 2-dimensional strain parameters to exclude acute rejection after heart transplantation: a multicenter study

Author

Goirigolzarri Artaza, Josebe, Mingo Santos, Susana, Larrañaga, José María, Osa, Ana, Sutil-Vega, Mario, Ruiz Ortiz, Martín, Corros, Cecilia, Vidal, Bárbara, Moñivas Palomero, Vanessa, Maneiro, Nicolás, Barbeito, Cayetana María, López-Vilella, Raquel, Li, Chi-Hion, Rodríguez Diego, Sara, Lambert, José Luis, Velásquez, Franciris, Crespo-Leiro, María G., Almenar, Luis, Mirabet, Sonia, Martínez Mingo, Alejandro, and Segovia Cubero, Javier

Published
2021
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7. Validación de la utilidad de los parámetros de deformación miocárdica para excluir el rechazo agudo tras el trasplante cardiaco: un estudio multicéntrico

Author

Goirigolzarri Artaza, Josebe, Mingo Santos, Susana, Larrañaga, José María, Osa, Ana, Sutil-Vega, Mario, Ruiz Ortiz, Martín, Corros, Cecilia, Vidal, Bárbara, Moñivas Palomero, Vanessa, Maneiro, Nicolás, Barbeito, Cayetana María, López-Vilella, Raquel, Li, Chi-Hion, Rodríguez Diego, Sara, Lambert, José Luis, Velásquez, Franciris, Crespo-Leiro, María G., Almenar, Luis, Mirabet, Sonia, Martínez Mingo, Alejandro, and Segovia Cubero, Javier

Published
2021
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9. Kinesiophobia and associated variables in patients with heart failure

Author

Sentandreu-Mano, Trinidad, Deka, Pallav, Almenar, Luis, Tomas, Jose M., Ferrer-Sargues, Francisco-Jose, Lopez-Vilella, Raquel, Klompstra, Leonie, Marques-Sule, Elena, Sentandreu-Mano, Trinidad, Deka, Pallav, Almenar, Luis, Tomas, Jose M., Ferrer-Sargues, Francisco-Jose, Lopez-Vilella, Raquel, Klompstra, Leonie, and Marques-Sule, Elena

Abstract

Aims Patients with heart failure (HF) can exhibit kinesiophobia, an excessive, debilitating, and irrational fear of movement. This study aimed to enhance the understanding of kinesiophobia in patients with HF by analysing associations with the following variables: musculoskeletal pain, quality of life, quality of sleep, functional capacity, disability, frailty, sex, and age. Methods and results In this cross-sectional study, 107 participants were included, with ages ranging from 28 to 97 years (57% men, mean age 73.18 +/- 12.68 years). Multiple regression analyses were performed with all variables, including polynomial regressions for variables with a non-linear relationship. Kinesiophobia was significantly correlated (P < 0.01) with musculoskeletal pain, quality of life, quality of sleep, functional capacity, disability, and being at risk of frailty, while age and sex were not statistically significant. Frailty disability and musculoskeletal pain intensity were variables linearly associated with kinesiophobia, while quality of sleep and disability had a non-linear relationship with kinesiophobia. Conclusion Kinesiophobia needs to be evaluated and better understood in patients with HF to improve physical activity and exercise adherence. This study found that musculoskeletal pain intensity, quality of sleep, disability, and frailty risk have a significant association with kinesiophobia in patients with HF. Our results suggest multi-dimensional associations of kinesiophobia in patients with HF, which require further examination and understanding. [Graphics] ., Funding Agencies|project Successful Aging in Europe: Trajectories and Processes to Act on psychological, social, and physical frailty; MCIN/AEI [PID2021-124418OB-I00]; ERDF A way of making Europe

Published
2024
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10. Economic analysis of intermittent intravenous outpatient treatment with levosimendan in advanced heart failure in Spain

Author

Pinilla, José Manuel García, Almenar, Luis, Crespo-Leiro, María G., Sionis, Alessandro, Blasco, Teresa, Pascual-Figal, Domingo, Gonzalez-Vilchez, Francisco, Lambert-Rodríguez, José Luis, Grau, Maria, Manito Lorite, Nicolás, Rubio-Rodríguez, Darío, González Costello, José, Díez López, Carles, Enjuanes Grau, Cristina, Segovia-Cubero, Javier, Delgado Jimenez, Juan Francisco, Campo Sien, Carlos, Rubio-Terrés, Carlos, and Comín-Colet, Josep

Published
2020
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11. Análisis económico del tratamiento ambulatorio intermitente con levosimendán de la insuficiencia cardiaca avanzada en España

Author

Pinilla, José Manuel García, Almenar, Luis, Crespo-Leiro, María G., Sionis, Alessandro, Blasco, Teresa, Pascual-Figal, Domingo, Gonzalez-Vilchez, Francisco, Lambert-Rodríguez, José Luis, Grau, Maria, Manito Lorite, Nicolás, Rubio-Rodríguez, Darío, González Costello, José, Díez López, Carles, Enjuanes Grau, Cristina, Segovia-Cubero, Javier, Delgado Jimenez, Juan Francisco, Campo Sien, Carlos, Rubio-Terrés, Carlos, and Comín-Colet, Josep

Published
2020
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12. Consenso de expertos en la asistencia multidisciplinaria y el abordaje integral de la insuficiencia cardiaca. Desde el alta hospitalaria hasta la continuidad asistencial con primaria

Author

Valle, Alfonso, Arrarte, Vicente, Pinilla, José Manuel García, Campuzano, Raquel, de Pablo, Carmen, Beltrán, Paola, Quintana, Antonio García, Almenar, Luis, Bover, Ramón, Ortiz, Carolina, Fernández, Rosa, Castro, Almudena, Sanz, Paz, Sanz, María, Lambert, José Luis, Miró, Vicente, Armengol, Xavier, Crespo, Marisa, Montiel, Ángel, Recio, Alejandro, Pereira, Eva, Oria, Garazi, Chabbar, Maruan, Gómez, María Inés, Alarcón, José Antonio, Garza, Fernando, Dominguez, Juan Carlos Castillo, Gil, Carlos Peña, Heviá, Sergio, Segovia, Javier, Mora, Javier, Gavira, Juan José, and Bello, Maruja

Published
2020
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14. Improvement in left atrial strain following ferric carboxymaltose in heart failure: an analysis of the Myocardial‐IRON trial.

Author

Santas, Enrique, del Canto, Irene, Cardells, Ingrid, Miñana, Gema, Llàcer, Pau, Almenar, Luis, Fácila, Lorenzo, Maceira, Alicia M., Sanchis, Juan, and Núñez, Julio

Subjects
LEFT heart atrium, FAILURE analysis, HEART failure, VENTRICULAR ejection fraction, IRON deficiency
Abstract

Aims: Iron deficiency (ID) is associated with an impaired cardiac function and remodelling in heart failure (HF). Treatment with ferric carboxymaltose (FCM) has been showed recently to improve biventricular systolic function and ventricular strain parameters in patients with HF with reduced ejection fraction and ID, but there is no evidence on the benefit of FCM on the left atrium (LA). In this study, we aimed to evaluate the effect of FCM on LA longitudinal strain (LA‐LS). Methods and results: This is a post hoc subanalysis of a double‐blind, placebo‐controlled, randomized clinical trial that enrolled 53 ambulatory patients with HF, left ventricular ejection fraction (LVEF) < 50%, and ID [Myocardial‐IRON trial (NCT03398681)], treated with FCM or placebo. Cardiac magnetic resonance‐featured tracking (CMR‐FT) strain changes were evaluated before and 7 and 30 days after randomization using linear mixed regression analysis. The median age of the sample was 68 years (interquartile range: 64–76), and 20 (69%) were men. Mean ± standard deviation of LVEF was 39 ± 11%, and most (97%) were in stable New York Heart Association class II. At baseline, mean LA‐LS was −8.9 ± 3.5%. At 30 days, and compared with placebo, LA‐LS significantly improved in those allocated to FCM treatment arm (LA‐LS = −12.0 ± 0.5 and −8.5 ± 0.6, respectively; − ∆ 3.55%, P < 0.001). Conclusions: In patients with stable HF, LVEF < 50%, and ID, treatment with FCM was associated with short‐term improvements in LA‐LS assessed by CMR‐FT. Future works should assess the potential benefit of iron repletion on LA function. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Levosimendán ambulatorio repetitivo como puente al trasplante cardiaco

Author

Juan Bagudá, Javier de, primary, Frutos, Fernando de, additional, López-Vilella, Raquel, additional, Mallón, David Couto, additional, Guzman-Bofarull, Joan, additional, Blazquez-Bermejo, Zorba, additional, Cobo-Belaustegui, Manuel, additional, Mitroi, Cristina, additional, Pastor-Pérez, Francisco J., additional, Moliner-Abós, Carlos, additional, Rangel-Sousa, Diego, additional, Díaz-Molina, Beatriz, additional, Tobar-Ruiz, Javier, additional, Gonzalez, Nahikari Salterain, additional, Manuel García-Pinilla, José, additional, Carmena, María Dolores García-Cosío, additional, Crespo-Leiro, María Generosa, additional, Dobarro, David, additional, Almenar, Luis, additional, Delgado-Jiménez, Juan F., additional, Paredes-Galán, Emilio, additional, González-Vílchez, Francisco, additional, and González-Costello, José, additional

Published
2023
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19. Evaluation of humoral immunity profiles to identify heart recipients at risk for development of severe infections: A multicenter prospective study

Author

Sarmiento, Elizabeth, Jaramillo, Maria, Calahorra, Leticia, Fernandez-Yañez, Juan, Gomez-Sanchez, Miguel, Crespo-Leiro, Maria G., Paniagua, Maria, Almenar, Luis, Cebrian, Monica, Rabago, Gregorio, Levy, Beltran, Segovia, Javier, Gomez-Bueno, Manuel, Lopez, Javier, Mirabet, Sonia, Navarro, Joaquin, Rodriguez-Molina, Juan Jose, Fernandez-Cruz, Eduardo, and Carbone, Javier

Published
2017
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20. What motivates heart transplantation patients to exercise and engage in physical activity? A network analysis.

Author

Marques-Sule, Elena, Hansen, Dominique, Almenar, Luis, Deka, Pallav, Sentandreu-Mañó, Trinidad, López-Vilella, Raquel, Klompstra, Leonie, and Machado, Felipe V C

Subjects
CROSS-sectional method, PHOBIAS, MUSCULOSKELETAL pain, EXERCISE therapy, QUESTIONNAIRES, SEDENTARY lifestyles, FRAIL elderly, TREATMENT effectiveness, FUNCTIONAL status, DESCRIPTIVE statistics, HEART transplantation, MOTIVATION (Psychology), RESEARCH methodology, BODY movement, SLEEP quality, DATA analysis software, CONFIDENCE intervals, PHYSICAL activity, MENTAL depression, DIET, REHABILITATION
Abstract

Aims After heart transplantation (HTx), increments in physical activity (PA) are strongly recommended. However, participation rates in exercise-based cardiac rehabilitation and engagement in PA are insufficient in many patients. Hence, this study aimed to explore the central factors and the interconnections among distinct types of motivation to exercise, PA, sedentary time, psychosomatic, diet, and activity limitation characteristics in post-HTx patients. Methods and results This is a cross-sectional study involving 133 post-HTx patients (79 men, mean age 57 ± 13 years, mean time from transplantation 55 ± 42 months) recruited from an outpatient clinic in Spain. The patients were asked to fill in questionnaires measuring self-reported PA, motivation to exercise, kinesiophobia, musculoskeletal pain, quality of sleep, depression, functional capacity, frailty, sarcopenia risk, and diet quality. Two network structures were estimated: one network including PA and one network including sedentary time as nodes. The relative importance of each node in the network structures was determined using centrality analyses. According to the strength centrality index, functional capacity and identified regulation (subtypes of motivation to exercise) are the two most central nodes of the network (strength: z -score = 1.35–1.51). Strong and direct connections emerged between frailty and PA and between sarcopenia risk and sedentary time. Conclusion Functional capacity and autonomous motivation to exercise are the most promising targets of interventions to improve PA levels and sedentary time in post-HTx patients. Furthermore, frailty and sarcopenia risk were found to mediate the effects of several other factors on PA and sedentary time. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Correlates of musculoskeletal pain and kinesiophobia in older adults with heart failure: A structural equation model

Author

Sentandreu-Man, Trinidad, Deka, Pallav, Almenar, Luis, Tomas, Jose M., Alguacil-Sancho, Laura, Lopez-Vilella, Raquel, Klompstra, Leonie, Marques-Sule, Elena, Sentandreu-Man, Trinidad, Deka, Pallav, Almenar, Luis, Tomas, Jose M., Alguacil-Sancho, Laura, Lopez-Vilella, Raquel, Klompstra, Leonie, and Marques-Sule, Elena

Abstract

The study aimed to study the influence of musculoskeletal pain on kinesiophobia in patients with heart failure. This cross-sectional study recruited 107 heart failure patients aged 73.1812.68 years (57% men) from an outpatient setting. Participants self-reported pain using the Musculoskeletal System Assessment Inventory and the Cornell Musculoskeletal Discomfort Questionnaire. Kinesiophobia was assessed with the Tampa Scale for Kinesiophobia-11. About 62% reported musculoskeletal pain, with knees (16.8%) and lower back (12.%) being the most painful locations. About 31% reported moderate levels and 24% indicated high levels of kinesiophobia. There were positive and significant associations between the indicators of pain and kinesiophobia. Results showed an adequate structural equation model fit to the data with musculoskeletal pain factors explaining 22.09% of the variance in kinesiophobia. Assessment of kinesiophobia in patients with heart failure with musculoskeletal pain is essential to improve self-care and overall quality of life. & COPY; 2023 Elsevier Inc. All rights reserved., Funding Agencies|MCIN/AEI [PID2021-124418OB-I00]; ERDF A way of making Europe

Published
2023
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24. What motivates heart transplantation patients to exercise and engage in physical activity? A network analysis

Author

Marques-Sule, Elena, Hansen, Dominique, Almenar, Luis, Deka, Pallav, Sentandreu-Mano, Trinidad, Lopez-Vilella, Raquel, Klompstra, Leonie, Machado, Felipe V. C., Marques-Sule, Elena, Hansen, Dominique, Almenar, Luis, Deka, Pallav, Sentandreu-Mano, Trinidad, Lopez-Vilella, Raquel, Klompstra, Leonie, and Machado, Felipe V. C.

Abstract

Aims After heart transplantation (HTx), increments in physical activity (PA) are strongly recommended. However, participation rates in exercise-based cardiac rehabilitation and engagement in PA are insufficient in many patients. Hence, this study aimed to explore the central factors and the interconnections among distinct types of motivation to exercise, PA, sedentary time, psychosomatic, diet, and activity limitation characteristics in post-HTx patients. Methods and results This is a cross-sectional study involving 133 post-HTx patients (79 men, mean age 57 +/- 13 years, mean time from transplantation 55 +/- 42 months) recruited from an outpatient clinic in Spain. The patients were asked to fill in questionnaires measuring self-reported PA, motivation to exercise, kinesiophobia, musculoskeletal pain, quality of sleep, depression, functional capacity, frailty, sarcopenia risk, and diet quality. Two network structures were estimated: one network including PA and one network including sedentary time as nodes. The relative importance of each node in the network structures was determined using centrality analyses. According to the strength centrality index, functional capacity and identified regulation (subtypes of motivation to exercise) are the two most central nodes of the network (strength: z-score = 1.35-1.51). Strong and direct connections emerged between frailty and PA and between sarcopenia risk and sedentary time. Conclusion Functional capacity and autonomous motivation to exercise are the most promising targets of interventions to improve PA levels and sedentary time in post-HTx patients. Furthermore, frailty and sarcopenia risk were found to mediate the effects of several other factors on PA and sedentary time.

Published
2023
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30. Influencia del perfil clínico del donante, receptor y tiempo de isquemia en la supervivencia del trasplante cardíaco. Subanálisis del Registro Español de Trasplante Cardíaco

Author

Paniagua, María J., Almenar, Luis, Palomo, Jesús, Segovia, Javier, Delgado, Juan, Lage, Ernesto, González, Francisco, Pérez-Villa, Félix, Arizón, José M., Manito, Nicolás, Brossa, Vicens, Díaz-Molina, Beatriz, Blasco, Teresa, de la Fuente, Luis, Pascual, Domingo, Rábago, Gregorio, García-Guereta, Luis, Albert, Dimpna C., and Crespo-Leiro, María G.

Published
2015
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36. A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction

Author

Rao, Sunil V., primary, Kirsch, Bodo, additional, Bhatt, Deepak L., additional, Budaj, Andrzej, additional, Coppolecchia, Rosa, additional, Eikelboom, John, additional, James, Stefan K., additional, Jones, W. Schuyler, additional, Merkely, Bela, additional, Keller, Lars, additional, Hermanides, Renicus S., additional, Campo, Gianluca, additional, Ferreiro, José Luis, additional, Shibasaki, Taro, additional, Mundl, Hardi, additional, Alexander, John H., additional, Hengstenberg, Christian, additional, Steinwender, Clemens, additional, Alber, Hannes, additional, Steringer-Mascherbauer, Regina, additional, Schober, Andreas, additional, Auer, Johann, additional, Roithinger, Franz Xaver, additional, von Lewinski, Dirk, additional, Moertl, Deddo, additional, Huber, Kurt, additional, Coussement, Patrick, additional, Hoffer, Etienne, additional, Beauloye, Christophe, additional, Janssens, Luc, additional, Vranckx, Pascal, additional, De Raedt, Herbert, additional, Vanassche, Thomas, additional, Vrolix, Matthias, additional, Rokyta, Richard, additional, Parenica, Jiri, additional, Pelouch, Radek, additional, Motovska, Zuzanna, additional, Alan, David, additional, Kettner, Jiri, additional, Polasek, Rostislav, additional, Cermak, Ondrej, additional, Sedlon, Pavel, additional, Hanis, Jiri, additional, Novak, Martin, additional, Belohlavek, Jan, additional, Horacek, Thomas, additional, Leggewie, Stefan, additional, Wenzel, Philip, additional, vom Dahl, Juergen, additional, Sievers, Burkhard, additional, Pulz, Jan, additional, Schellong, Sebastian, additional, Clemmensen, Peter, additional, Muller-Hennessen, Matthias, additional, Rassaf, Tienush, additional, Falukozi, Jozsef, additional, Ruzsa, Zoltan, additional, Tomcsanyi, Janos, additional, Csanadi, Zoltan, additional, Herczeg, Bela, additional, Koszegi, Zsolt, additional, Vorobcsuk, Andras, additional, Kiss, Robert, additional, Baranyai, Csaba, additional, Dezsi, Csaba, additional, Lupkovics, Geza, additional, Rossini, Roberta, additional, Scherillo, Marino, additional, Sergio Saba, Pier, additional, Calogero Campo, Gianluca, additional, Calo, Leonardo, additional, Nassiacos, Daniele, additional, Quadri, Giorgio, additional, Sciahbasi, Alessandro, additional, Silvio Marenzi, Gian Carlo, additional, Reimers, Bernhard, additional, Perna, Gian Piero, additional, Sacca, Salvatore, additional, Fattore, Luciano, additional, Brunelli, Claudio, additional, Picchi, Andrea, additional, Kuramochi, Takehiko, additional, Kondo, Kazuhisa, additional, Aoyama, Takahiko, additional, Kudoh, Takashi, additional, Yamamoto, Tadashi, additional, Takaya, Tomofumi, additional, Mukai, Yasushi, additional, Fukui, Kazuki, additional, Morioka, Nobuyuki, additional, Ando, Kenji, additional, Yamamuro, Atsushi, additional, Morita, Yasuhiro, additional, Koga, Yasuaki, additional, Watanabe, Tetsuya, additional, Sakamoto, Tomohiro, additional, Maebuchi, Daisuke, additional, Takahashi, Akihiko, additional, Yonetsu, Taishi, additional, Kakuta, Tsunekazu, additional, Nishina, Hidetaka, additional, Oemrawsingh, Rohit, additional, Dorman, Reinhart, additional, Oude Ophius, Ton, additional, Prins, Paco, additional, al Windy, N.Y.Y., additional, Zoet-Nugteren, S.K., additional, Hermanides, Rik, additional, van Eck, Martijn, additional, Scherptong, Roderick, additional, Cornel, J.H., additional, Damman, Peter, additional, Bech, Gerhard, additional, Torquay, R., additional, Kietselaer, Bas, additional, Grzelakowski, Pawel, additional, Krzysztof, Dyrbus, additional, Miekus, Pawel, additional, Przybylski, Andrzej, additional, Zarebinski, Maciej, additional, Balsam, Pawel, additional, Szachniewicz, Joanna, additional, Gierlotka, Marek, additional, Tycinska, Agnieszka, additional, Iniguez Romo, Andres, additional, Fernandez Ortiz, Antonio, additional, Carrasquer Cucarella, Anna, additional, Sanmartin Fernandez, Marcelo, additional, Sionis, Alessandro, additional, Bueno Zamora, Hector, additional, Ferreiro Gutierrez, Jose Luis, additional, Almenar, Luis, additional, Ferreira Gonzalez, Ignacio, additional, Pascual Figal, Domingo A., additional, Almendro Delia, Manuel, additional, Jimenez Fernandez, Miriam, additional, Skeppholm, Mika, additional, Zedigh, Crister, additional, Angeras, Oskar, additional, Lauermann, Jorg, additional, Erlinge, David, additional, Gustafsson, Robin, additional, Mooe, Thomas, additional, Utreras, Alejandro, additional, James, Stefan, additional, Grimfjard, Per, additional, Pedrazzini, Giovanni, additional, Mach, Francois, additional, Fournier, Stephane, additional, Haegeli, Laurent, additional, Beer, Jurg H., additional, Leibundgut, Gregor, additional, Kobza, Richard, additional, Kaiser, Christoph, additional, Kunadian, Vijay, additional, Al-Lamee, Rasha, additional, Gorog, Diana, additional, Khan, Sohail, additional, Trevelyan, Jasper, additional, Toor, Iqbal, additional, Smith, James, additional, Purushottam, Bhaskar, additional, Treasure, Charles, additional, Arena, Frank, additional, Vedere, Amarnath, additional, Henderson, David, additional, Gilani, Syed, additional, Jones, Alonzo, additional, Carrillo-Jimenez, Rodolfo, additional, Gillespie, Eve, additional, Marhefka, Gregary, additional, Wang, David, additional, Olson, Charles, additional, Bloom, Stephen, additional, Iftikhar, Faizan, additional, Brabham, David, additional, McGinty, John, additional, Thompson, Charles, additional, Talano, James, additional, Ginete, Wilson, additional, Williams, Marcus, additional, Masud, Ali, additional, Ariani, Mehrdad, additional, Bitar, Fahed, additional, Wang, Thomas, additional, and Samuelson, Bradley, additional

Published
2022
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37. The impact of the prevention strategies on the indirect effects of CMV infection in solid organ transplant recipients

Author

Roman, Antonio, Manito, Nicolás, Campistol, Josep Maria, Cuervas-Mons, Valentín, Almenar, Luis, Arias, Manuel, Casafont, Fernando, del Castillo, Domingo, Crespo-Leiro, María G., Delgado, Juan F., Herrero, J. Ignacio, Jara, Paloma, Morales, José M., Navarro, Mercedes, Oppenheimer, Federico, Prieto, Martín, Pulpón, Luis A., Rimola, Antoni, Serón, Daniel, and Ussetti, Piedad

Published
2014
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39. Primary graft failure after heart transplantation: Characteristics in a contemporary cohort and performance of the RADIAL risk score

Author

Cosío Carmena, M. Dolores G., Gómez Bueno, Manuel, Almenar, Luis, Delgado, Juan F., Arizón, Jose M., González Vilchez, Francisco, Crespo-Leiro, Maria G., Mirabet, Sonia, Roig, Eulalia, Pérez Villa, Félix, Fernández-Yañez, Juan F., Lambert, Jose L., Manito, Nicolás, Fuente, Luis, Sanz Julve, Maria L., Pascual, Domingo, Rábago, Gregorio, Millán, Isabel, Alonso-Pulpón, Luis A., and Segovia, Javier

Published
2013
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44. Physical activity enjoyment, exercise motivation, and physical activity in patients with heart failure : A mediation analysis

Author

Verheijden Klompstra, Leonie, Deka, Pallav, Almenar, Luis, Pathak, Dola, Munoz-Gomez, Elena, Lopez-Vilella, Raquel, Marques-Sule, Elena, Verheijden Klompstra, Leonie, Deka, Pallav, Almenar, Luis, Pathak, Dola, Munoz-Gomez, Elena, Lopez-Vilella, Raquel, and Marques-Sule, Elena

Abstract

Objective To determine whether physical activity enjoyment mediated the association between motivation and physical activity in patients with heart failure. Design and setting A cross-sectional study at the cardiology clinic in the university hospital in Valencia, Spain Subjects A total of 134 patients with heart failure. Main measurements Physical activity was assessed with the International Physical Activity Questionnaire, motivation was assessed with the Exercise Motivation Index and Physical Activity Enjoyment was assessed with the Physical Activity Enjoyment Scale. Analysis Mediation analysis using Hayes PROCESS macro (Model 4) for SPSS. Results The mean age of the sample was 70 +/- 14 years, 47 patients were female (35%), and 87 patients were in New York Heart Association I/II (67%). A positive relationship was found between exercise motivation and physical activity (t = 4.57, p < .01) and physical activity enjoyment (t = 11.52, p < .01). Physical activity enjoyment was found to positively affect physical activity (t = 3.50, p < .01). After controlling for physical activity enjoyment, the effect of exercise motivation on physical activity changed from a significant to non-significant (t = 1.33, p = .89), indicating that enjoyment completely mediated the relationship between motivation and physical activity. Overall, 25% of the variation in physical activity was explained by the mediation model. Conclusions Physical activity enjoyment mediates the relationship between exercise motivation and physical activity in patients with heart failure. This means that even highly motivated heart failure patients may not be physically active if they do not enjoy the physical activity.

Published
2022
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45. Physical Activity Readiness in Patients with Heart Failure

Author

Marques-Sule, Elena, Deka, Pallav, Almenar, Luis, Pathak, Dola, Lopez-Vilella, Raquel, Klompstra, Leonie, Marques-Sule, Elena, Deka, Pallav, Almenar, Luis, Pathak, Dola, Lopez-Vilella, Raquel, and Klompstra, Leonie

Abstract

The aim of this study was to explore the readiness for physical activity (PA) and its related factors in patients with heart failure. This cross-sectional study included 163 patients with heart failure (mean age 66 +/- 16, 50% female). The ability to safely engage in PA was assessed with the PA Readiness Questionnaire (PAR-Q). Psychological readiness was measured using two questionnaires, namely: Exercise Self-efficacy Scale and the Motivation for PA and Exercise/Working Out. A multivariate analysis of covariance was conducted to test the effect of background variables on readiness for PA. 64% (n = 105) of patients reported not being able to safely engage in PA, 80% (n = 129) reported low self-efficacy, and 45% (n = 74) were extrinsically motivated indicating external factors drove their motivation. Factors that positively influenced the PA readiness included lower age (p < 0.01), being male (p < 0.01), being married (p < 0.01), having higher education (p < 0.01), being in NYHA-class I compared with II (p < 0.01), less time since diagnosis (p < 0.01), lower BMI (p = 0.02), and not suffering from COPD (p = 0.02). Prior to recommending exercise, assessment of safety to engage in PA along with self-efficacy and motivation in patients with heart failure is essential.

Published
2022
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46. Influence on kinesiophobia by disability, physical, and behavioural variables after a heart transplantation( )

Author

Marques-Sule, Elena, Soderlund, Anne, Almenar, Luis, Victoria Espi-Lopez, Gemma, Lopez-Vilella, Raquel, Bäck, Maria, Marques-Sule, Elena, Soderlund, Anne, Almenar, Luis, Victoria Espi-Lopez, Gemma, Lopez-Vilella, Raquel, and Bäck, Maria

Abstract

Background From clinical experience, kinesiophobia represents a barrier to being physically active after a heart transplantation (HTx), but studies in this field are lacking. Identifying the factors associated with kinesiophobia is essential to determine preventive interventions to avoid negative consequences for health. Aims To study the influence of disability, physical, and behavioural variables on kinesiophobia in patients with an HTx. Methods A total of 117 patients with an HTx [51 women; mean age 56 (SD 12.1) years] were recruited at an outpatient clinic. These patients were asked to fill in questionnaires measuring kinesiophobia, self-reported physical activity (PA), exercise self-efficacy, motivation for PA, and disability. A multiple regression analysis was conducted to examine the statistical prediction of kinesiophobia as a dependent variable, with the questionnaires, gender and education as independent variables. Results The independent variables explained 70% of the variance in kinesiophobia. The prediction model was significant (F = 32.1, P < 0.001). The time from transplantation (standardised coefficient, beta; -0.17), the total exercise self-efficacy (-0.16), extrinsic motivation (-0.23), and the disability total score (0.63) were significant predictors of kinesiophobia, while the independent variables of gender, education, intrinsic motivation, and the PA total score were not significant. Conclusions This study highlights that a short time from transplantation, low self-efficacy, low extrinsic motivation, and a high level of disability explained high levels of kinesiophobia in patients after an HTx. These results suggest that an increased awareness of the biopsychosocial health perspective is essential in order to maximising patient outcomes after an HTx.

Published
2022
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49. New concepts and best practices for management of pre- and post-transplantation cancer

Author

Campistol, Josep M., Cuervas-Mons, Valentín, Manito, Nicolás, Almenar, Luis, Arias, Manuel, Casafont, Fernando, del Castillo, Domingo, Crespo-Leiro, María G., Delgado, Juan F., Herrero, J. Ignacio, Jara, Paloma, Morales, José M., Navarro, Mercedes, Oppenheimer, Federico, Prieto, Martín, Pulpón, Luis A., Rimola, Antoni, Román, Antonio, Serón, Daniel, and Ussetti, Piedad

Published
2012
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