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1. Biochemical and nutritional determinants of non-alcoholic fatty liver disease in Omani adult patients: a case-control study.

Author

Al Ghaithi, Fatma, Waly, Mostafa I., Al-Farsi, Yahya, Al Mukhaini, Zainab, Al Balushi, Ruqaiya, and Almashrafi, Ahmed

Subjects
NON-alcoholic fatty liver disease, LIVER enzymes, BIOMARKERS, CIRRHOSIS of the liver, INTERNAL medicine
Abstract

Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is a risk factor for atherosclerosis, diabetes, kidney disease, and liver cirrhosis. Limited research exists on the biochemical and nutritional elements influencing NAFLD among adult patients in Oman. Objective : This study aimed to characterize the biochemical parameters and nutritional factors of Omani adults diagnosed with NAFLD at the Diwan Polyclinic in Muscat, Oman. Methods: This retrospective case–control study included 104 participants (52 cases and 52 controls) who have 2 or more risk factors for NAFLD and were referred to the Radiology department from January 2021 to January 2022 for abdominal ultrasound after Internal Medicine consultations. A validated scale, incorporating a semi-quantitative food frequency questionnaire, was employed. Results: The study revealed a significantly higher risk of NAFLD among men (69%) compared to women (31%). A common characteristic among participants was a prior diabetes diagnosis, 61.5% of the case group and 65% of the control group. While average liver enzyme levels were within the normal range for both groups, alanine transaminase levels were notably elevated in the case group. The case group exhibited a significantly higher average caloric intake than the control group. Conclusion: NAFLD is significantly more common among men. Alanine transaminase is significantly high in NAFLD group, which might be considered as a biochemical marker for NAFLD, but further investigations are needed. Moreover, high daily caloric intake is directly related to NAFLD. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Optimising cardiac services using routinely collected data and discrete event simulation

Author

Almashrafi, Ahmed and Aylin, Paul

Subjects
616.1
Abstract

Background: The current practice of managing hospital resources, including beds, is very much driven by measuring past or expected utilisation of resources. This practice, however, doesn't reflect variability among patients. Consequently, managers and clinicians cannot make fully informed decisions based upon these measures which are considered inadequate in planning and managing complex systems. Aim: to analyse how variation related to patient conditions and adverse events affect resource utilisation and operational performance. Methods: Data pertaining to cardiac patients (cardiothoracic and cardiology, n=2241) were collected from two major hospitals in Oman. Factors influential to resource utilisation were assessed using logistic regressions. Other analysis related to classifying patients based on their resource utilisation was carried out using decision tree to assist in predicting hospital stay. Finally, discrete event simulation modelling was used to evaluate how patient factors and postoperative complications are affecting operational performance. Results: 26.5% of the patients experienced prolonged Length of Stay (LOS) in intensive care units and 30% in the ward. Patients with prolonged postoperative LOS had 60% of the total patient days. Some of the factors that explained the largest amount of variance in resource use following cardiac procedure included body mass index, type of surgery, Cardiopulmonary Bypass (CPB) use, non-elective surgery, number of complications, blood transfusion, chronic heart failure, and previous angioplasty. Allocating resources based on patient expected LOS has resulted in a reduction of surgery cancellations and waiting times while overall throughput has increased. Complications had a significant effect on perioperative operational performance such as surgery cancellations. The effect was profound when complications occurred in the intensive care unit where a limited capacity was observed. Based on the simulation model, eliminating some complications can enlarge patient population. Conclusion: Integrating influential factors into resource planning through simulation modelling is an effective way to estimate and manage hospital capacity.

Published
2016
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4. Status of patient safety culture in Arab countries: a systematic review

Author

Elmontsri, Mustafa, Almashrafi, Ahmed, Banarsee, Ricky, and Majeed, Azeem

Subjects
TEAMS, Attitude of Health Personnel, PLAN, education, HOSPITAL SURVEY, HARM, Middle East, Safety Culture, Medicine, General & Internal, Stakeholder Participation, General & Internal Medicine, Humans, OUTCOMES, Science & Technology, MEDICINE, Research, Communication, Organizational Culture, Quality Improvement, PUBLIC HOSPITALS, NURSES PERCEPTIONS, RELIABILITY, Arab Countries, Health Services Research, Patient Safety, ADVERSE EVENTS, Life Sciences & Biomedicine
Abstract

Objectives To explore the status of patient safety culture in Arab countries based on the findings of the Hospital Survey on Patient Safety Culture (HSPSC). Design Systematic review. Methods We performed electronic searches of the MEDLINE, EMBASE, CINAHL, ProQuest and PsychINFO, Google Scholar and PubMed databases, with manual searches of bibliographies of included articles and key journals. We included studies that were conducted in the Arab countries that were focused on patient safety culture. 2 reviewers independently verified that the studies met the inclusion criteria and critically assessed the quality of the studies. Results 18 studies met our inclusion criteria. The review identified that non-punitive response to error is seen as a serious issue which needs to be improved. Healthcare professionals in the Arab countries tend to think that a ‘culture of blame’ still exists that prevents them from reporting incidents. We found an overall similarity between the reported composite score for dimension of teamwork within units in all of the reviewed studies. Teamwork within units was found to be better than teamwork across hospital units. All of the reviewed studies reported that organisational learning and continuous improvement was satisfactory as the average score of this dimension for all studies was 73.2%. Moreover, the review found that communication openness seems to be a concerning issue for healthcare professionals in the Arab countries. Conclusions There is a need to promote patient safety culture as a strategy for improving the patient safety in the Arab world. Improving patient safety culture should include all stakeholders, like policymakers, healthcare providers and those responsible for medical education. This review was limited only to English language publications. The varied settings in which the HSPSC was used may have influenced the areas of strengths and weaknesses as healthcare workers' perception of safety culture may differ.

Published
2016

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