145 results on '"Allisyn C. Moran"'
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2. Implementation of maternal and perinatal death surveillance and response (MPDSR) in humanitarian settings: insights and experiences of humanitarian health practitioners and global technical expert meeting attendees
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Neal Russell, Hannah Tappis, Jean Paul Mwanga, Benjamin Black, Kusum Thapa, Endang Handzel, Elaine Scudder, Ribka Amsalu, Jyoti Reddi, Francesca Palestra, and Allisyn C. Moran
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Humanitarian ,Maternal ,Perinatal ,Mortality ,Surveillance ,Review ,Special situations and conditions ,RC952-1245 ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background Maternal and perinatal death surveillance and response (MPDSR) is a system of identifying, analysing and learning lessons from such deaths in order to respond and prevent future deaths, and has been recommended by WHO and implemented in many low-and-middle income settings in recent years. However, there is limited documentation of experience with MPDSR in humanitarian settings. A meeting on MPDSR in humanitarian settings was convened by WHO, UNICEF, CDC and Save the Children, UNFPA and UNHCR on 17th–18th October 2019, informed by semi-structured interviews with a range of professionals, including expert attendees. Consultation findings Interviewees revealed significant obstacles to full implementation of the MPDSR process in humanitarian settings. Many obstacles were familiar to low resource settings in general but were amplified in the context of a humanitarian crisis, such as overburdened services, disincentives to reporting, accountability gaps, a blame approach, and politicisation of mortality. Factors more unique to humanitarian contexts included concerns about health worker security and moral distress. There are varying levels of institutionalisation and implementation capacity for MPDSR within humanitarian organisations. It is suggested that if poorly implemented, particularly with a punitive or blame approach, MPDSR may be counterproductive. Nevertheless, successes in MPDSR were described whereby the process led to concrete actions to prevent deaths, and where death reviews have led to improved understanding of complex and rectifiable contextual factors leading to deaths in humanitarian settings. Conclusions Despite the challenges, examples exist where the lessons learnt from MPDSR processes have led to improved access and quality of care in humanitarian contexts, including successful advocacy. An adapted approach is required to ensure feasibility, with varying implementation being possible in different phases of crises. There is a need for guidance on MPDSR in humanitarian contexts, and for greater documentation and learning from experiences.
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- 2022
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3. Measures to assess quality of postnatal care: A scoping review
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Anna Galle, Allisyn C. Moran, Mercedes Bonet, Katriona Graham, Moise Muzigaba, Anayda Portela, Louise Tina Day, Godwin Kwaku Tuabu, Bianca De Sá é Silva, and Ann-Beth Moller
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Public aspects of medicine ,RA1-1270 - Abstract
High quality postnatal care is key for the health and wellbeing of women after childbirth and their newborns. In 2022, the World Health Organization (WHO) published global recommendations on maternal and newborn care for a positive postnatal care experience in a new WHO PNC guideline. Evidence regarding appropriate measures to monitor implementation of postnatal care (PNC) according to the WHO PNC guideline is lacking. This scoping review aims to document the measures used to assess the quality of postnatal care and their validity. The review was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Five electronic bibliographic databases were searched together with a grey literature search. Two reviewers independently screened and appraised identified articles. All data on PNC measures were extracted and mapped to the 2022 WHO PNC recommendations according to three categories: i) maternal care, ii) newborn care, iii) health system and health promotion interventions. We identified 62 studies providing measures aligning with the WHO PNC recommendations. For most PNC recommendations there were measures available and the highest number of recommendations were found for breastfeeding and the assessment of the newborn. No measures were found for recommendations related to sedentary behavior, criteria to be assessed before discharge, retention of staff in rural areas and use of digital communication. Measure validity assessment was described in 24 studies (39%), but methods were not standardized. Our review highlights a gap in existing PNC measures for several recommendations in the WHO PNC guideline. Assessment of the validity of PNC measures was limited. Consensus on how the quality of PNC should be measured is needed, involving a selection of priority measures and the development of new measures as appropriate.
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- 2023
4. Scaling up a monitoring and evaluation framework for sexual, reproductive, maternal, newborn, child, and adolescent health services and outcomes in humanitarian settings: A global initiative
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Loulou Kobeissi, Thidar Pyone, Allisyn C. Moran, Kathleen L. Strong, and Lale Say
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Humanitarian settings ,Internally displaced persons ,Maternal and child health ,Monitoring and evaluation ,Refugees ,Sexual and reproductive health ,Public aspects of medicine ,RA1-1270 - Abstract
Background: Reliable and rigorously collected sexual, reproductive, maternal, newborn, child, and adolescent (SRMNCAH) data from humanitarian settings are often sparse and variable in quality across different settings due to the lack of a standardised set of indicators across the different agencies working in humanitarian settings. This paper aims to summarise a WHO-led global initiative to develop and scale up an SRMNCAH monitoring and evaluation framework for humanitarian settings. Methods: This research revolved around three phases. The first and the last phase involved global consultations with lead international agencies active in SRMNCAH in humanitarian settings. The second phase tested the feasibility of the proposed indicators in Afghanistan, Bangladesh, the Democratic Republic of the Congo, and Jordan, using different qualitative research methods (interviews with 92 key informants, 26 focus group discussions with 142 key stakeholders, facility assessments and observations at 25 health facilities or sites). Results: Among the 73 proposed indicators, 47 were selected as core indicators and 26 as additional indicators. Generally, there were no major issues in collecting the proposed indicators, except for those indicators that relied on death reviews or population-level data. Service availability and morbidity indicators were encouraged. Abortion and SGBV indicators were challenging to collect due to political and sociocultural reasons. The HIV and PMTCT indicators were considered as core indicators, despite potential sensitivity in some settings. Existing data collection and reporting systems across the four assessed humanitarian settings were generally fragmented and inconsistent, mainly attributed to the lack of coordination among different agencies. Interpretation: Implementing agencies need to collaborate effectively to scale up this agreed-upon set of SRMNCAH framework to enhance accountability and transparency in humanitarian settings.
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- 2022
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5. Advancing maternal and perinatal health in low- and middle-income countries: A multi-country review of policies and programmes
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Uzma Syed, Mary V. Kinney, Ekaterine Pestvenidze, Alren O. Vandy, Karin Slowing, Janet Kayita, Alyona F. Lewis, Sartie Kenneh, Francis L. Moses, Atiya Aabroo, Ellen Thom, Qudsia Uzma, Nabila Zaka, Kim Rattana, Kannitha Cheang, Robert M. Kanke, Brigitte Kini, Jean-Bertin E. Epondo, and Allisyn C. Moran
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maternal health policy and programme ,country case studies ,evolution of maternal health ,factors influencing maternal and perinatal health ,low-and-middle-income countries ,Gynecology and obstetrics ,RG1-991 ,Women. Feminism ,HQ1101-2030.7 - Abstract
The Sustainable Development Goals prioritize maternal mortality reduction, with a global average target of < 70 per 100,000 live births by 2030. Current pace of reduction is far short of what is needed to achieve the global target. It is estimated that globally there are 300,000 maternal deaths, 2.4 million newborn deaths and 2 million stillbirths annually. Majority of these deaths occur in low-and-middle-income countries. Global initiatives like, Ending Preventable Maternal Mortality (EPMM) and Every Newborn Action Plan (ENAP), have outlined the broad strategies for maternal and newborn health programmes. A set of coverage targets and ten milestones were launched to support low-and-middle-income countries in accelerating progress in improving maternal, perinatal and newborn health and wellbeing. WHO, UNICEF and UNFPA, undertook a scoping review to understand how country strategies evolved in different contexts over the past two decades to improve maternal survival and wellbeing, and how countries in similar settings could accelerate progress considering the changing epidemiology and demography. Case studies were conducted to inform countries in similar settings and various global initiatives. Six countries were selected based on standard criteria—Cambodia, Democratic Republic of the Congo, Georgia, Guatemala, Pakistan and Sierra Leone representing different stages of the obstetric transition. A conceptual framework, encapsulating the interrelated factors impacting maternal health outcomes, was used to organize data collection and analysis. While all six countries made remarkable progress in improving maternal and perinatal health, the pace of progress and the factors influencing the successes and challenges varied across the countries. The context, opportunities and challenges varied from country to country. Two strategic directions were identified for next steps including the need to implement and evaluate innovative service delivery models using an updated obstetric transition as an organizing framework and expanding our vision to address equity and well-being.
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- 2022
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6. Count every newborn: EN-BIRTH study improving facility-based coverage and quality measurement in routine information systems
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Allisyn C. Moran and Jennifer Requejo
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Gynecology and obstetrics ,RG1-991 - Published
- 2021
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7. Respectful maternal and newborn care: measurement in one EN-BIRTH study hospital in Nepal
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Rejina Gurung, Harriet Ruysen, Avinash K. Sunny, Louise T. Day, Loveday Penn-Kekana, Mats Målqvist, Binda Ghimire, Dela Singh, Omkar Basnet, Srijana Sharma, Theresa Shaver, Allisyn C. Moran, Joy E. Lawn, Ashish KC, and EN-BIRTH Study Group
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Respectful maternal and newborn care ,Mistreatment ,Nepal ,Maternal ,Newborn ,Coverage ,Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background Respectful maternal and newborn care (RMNC) is an important component of high-quality care but progress is impeded by critical measurement gaps for women and newborns. The Every Newborn Birth Indicators Research Tracking in Hospitals (EN-BIRTH) study was an observational study with mixed methods assessing measurement validity for coverage and quality of maternal and newborn indicators. This paper reports results regarding the measurement of respectful care for women and newborns. Methods At one EN-BIRTH study site in Pokhara, Nepal, we included additional questions during exit-survey interviews with women about their experiences (July 2017–July 2018). The questionnaire was based on seven mistreatment typologies: Physical; Sexual; or Verbal abuse; Stigma/discrimination; Failure to meet professional standards of care; Poor rapport between women and providers; and Health care denied due to inability to pay. We calculated associations between these typologies and potential determinants of health – ethnicity, age, sex, mode of birth – as possible predictors for reporting poor care. Results Among 4296 women interviewed, none reported physical, sexual, or verbal abuse. 15.7% of women were dissatisfied with privacy, and 13.0% of women reported their birth experience did not meet their religious and cultural needs. In descriptive analysis, adjusted odds ratios and multivariate analysis showed primiparous women were less likely to report respectful care (β = 0.23, p-value
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- 2021
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8. Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Harriet Ruysen, Josephine Shabani, Claudia Hanson, Louise T. Day, Andrea B. Pembe, Kimberly Peven, Qazi Sadeq-ur Rahman, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Menna Narcis Tarimo, Allisyn C. Moran, Joy E. Lawn, and EN-BIRTH Study Group
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Birth ,Maternal ,Coverage ,Validity ,Survey ,Hospital records ,Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background Postpartum haemorrhage (PPH) is a leading cause of preventable maternal mortality worldwide. The World Health Organization (WHO) recommends uterotonic administration for every woman after birth to prevent PPH. There are no standardised data collected in large-scale measurement platforms. The Every Newborn Birth Indicators Research Tracking in Hospitals (EN-BIRTH) is an observational study to assess the validity of measurement of maternal and newborn indicators, and this paper reports findings regarding measurement of coverage and quality for uterotonics. Methods The EN-BIRTH study took place in five hospitals in Bangladesh, Nepal and Tanzania, from July 2017 to July 2018. Clinical observers collected tablet-based, time-stamped data. We compared observation data for uterotonics to routine hospital register-records and women’s report at exit-interview survey. We analysed the coverage and quality gap for timing and dose of administration. The register design was evaluated against gap analyses and qualitative interview data assessing the barriers and enablers to data recording and use. Results Observed uterotonic coverage was high in all five hospitals (> 99%, 95% CI 98.7–99.8%). Survey-report underestimated coverage (79.5 to 91.7%). “Don’t know” replies varied (2.1 to 14.4%) and were higher after caesarean (3.7 to 59.3%). Overall, there was low accuracy in survey data for details of uterotonic administration (type and timing). Register-recorded coverage varied in four hospitals capturing uterotonics in a specific column (21.6, 64.5, 97.6, 99.4%). The average coverage measurement gap was 18.1% for register-recorded and 6.0% for survey-reported coverage. Uterotonics were given to 15.9% of women within the “right time” (1 min) and 69.8% within 3 min. Women’s report of knowing the purpose of uterotonics after birth ranged from 0.4 to 64.9% between hospitals. Enabling register design and adequate staffing were reported to improve routine recording. Conclusions Routine registers have potential to track uterotonic coverage – register data were highly accurate in two EN-BIRTH hospitals, compared to consistently underestimated coverage by survey-report. Although uterotonic coverage was high, there were gaps in observed quality for timing and dose. Standardisation of register design and implementation could improve data quality and data flow from registers into health management information reporting systems, and requires further assessment.
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- 2021
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9. Study protocol for WHO and UNICEF estimates of global, regional, and national preterm birth rates for 2010 to 2019
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Ayesha De Costa, Ann-Beth Moller, Hannah Blencowe, Emily White Johansson, Laith Hussain-Alkhateeb, Eric O. Ohuma, Yemisrach B. Okwaraji, Jennifer Cresswell, Jennifer H. Requejo, Rajiv Bahl, Olufemi T. Oladapo, Joy E. Lawn, and Allisyn C. Moran
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Medicine ,Science - Abstract
Background Preterm birth is a leading cause of death among children under five years. Previous estimates indicated global preterm birth rate of 10.6% (14.8 million neonates) in 2014. We aim to update preterm birth estimates at global, regional, and national levels for the period 2010 to 2019. Methods Preterm birth is defined as a live birth occurring before 37 completed gestational weeks, or Discussion Accurate measurement of preterm birth is challenging in many countries given incomplete or unavailable data from national administrative sources, compounded by limited gestational age assessment during pregnancy to define preterm birth. Up-to-date modelled estimates will be an important resource to measure the global burden of preterm birth and to inform policies and programs especially in settings with a high burden of neonatal mortality. Trial registration PROSPERO registration:CRD42021237861.
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- 2021
10. Ending preventable maternal mortality: phase II of a multi-step process to develop a monitoring framework, 2016–2030
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R. Rima Jolivet, Allisyn C. Moran, Meaghan O’Connor, Doris Chou, Neelam Bhardwaj, Holly Newby, Jennifer Requejo, Marta Schaaf, Lale Say, and Ana Langer
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Maternal health ,Maternal mortality ,Indicators ,Monitoring ,Social determinants of health ,Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background In February 2015, the World Health Organization (WHO) released “Strategies toward ending preventable maternal mortality (EPMM)” (EPMM Strategies), a direction-setting report outlining global targets and strategies for reducing maternal mortality in the Sustainable Development Goal (SDG) period. In May 2015, the EPMM Working Group outlined a plan to develop a comprehensive monitoring framework to track progress toward the achievement of these targets and priorities. This monitoring framework was developed in two phases. Phase I, which focused on identifying indicators related to the proximal causes of maternal mortality, was completed in October 2015. This paper describes the process and results of Phase II, which was completed in November 2016 and aimed to build consensus on a set of indicators that capture information on the social, political, and economic determinants of maternal health and mortality. Findings A total of 150 experts from more than 78 organizations worldwide participated in this second phase of the process to develop a comprehensive monitoring framework for EPMM. The experts considered a total of 118 indicators grouped into the 11 key themes outlined in the EPMM report, ultimately reaching consensus on a set of 25 indicators, five equity stratifiers, and one transparency stratifier. Conclusion The indicators identified in Phase II will be used along with the Phase I indicators to monitor progress towards ending preventable maternal deaths. Together, they provide a means for monitoring not only the essential clinical interventions needed to save lives but also the equally important political, social, economic and health system determinants of maternal health and survival. These distal factors are essential to creating the enabling environment and high-performing health systems needed to ensure high-quality clinical care at the point of service for every woman, her fetus and newborn. They complement and support other monitoring efforts, in particular the “Survive, Thrive, and Transform” agenda laid out by the Global Strategy for Women’s, Children’s and Adolescents’ Health (2016-2030) and the SDG3 global target on maternal mortality.
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- 2018
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11. Methodology for a mixed-methods multi-country study to assess recognition of and response to maternal and newborn illness
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Allisyn C. Moran, Danielle Charlet, Supriya Madhavan, Kumudha Aruldas, Marie Donaldson, Fatuma Manzi, Monica Okuga, Alfonso Rosales, Vandana Sharma, Michael Celone, Neal Brandes, and James M. Sherry
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Maternal mortality ,Newborn mortality ,Developing country ,Qualitative research ,Care-seeking behavior ,Nutritional diseases. Deficiency diseases ,RC620-627 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Although maternal and newborn mortality have decreased 44 and 46% respectively between 1990 and 2015, achievement of ambitious Sustainable Development Goal targets requires accelerated progress. Mortality reduction requires a renewed focus on the continuum of maternal and newborn care from the household to the health facility. Although barriers to accessing skilled care are documented for specific contexts, there is a lack of systematic evidence on how women and families identify maternal and newborn illness and make decisions and subsequent care-seeking patterns. The focus of this multi-country study was to identify and describe illness recognition, decision-making, and care-seeking patterns across various contexts among women and newborns who survived and died to ultimately inform programmatic priorities moving forward. Methods This study was conducted in seven countries—Ethiopia, Tanzania, Uganda, Nigeria, India, Indonesia, and Nepal. Mixed-methods were utilized including event narratives (group interviews), in-depth interviews (IDIs), focus group discussions (FDGs), rapid facility assessments, and secondary analyses of existing program data. A common protocol and tools were developed in collaboration with study teams and adapted for each site, as needed. Sample size was a minimum of five cases of each type (e.g., perceived postpartum hemorrhage, maternal death, newborn illness, and newborn death) for each study site, with a total of 84 perceived PPH, 45 maternal deaths, 83 newborn illness, 55 newborn deaths, 64 IDIs/FGDs, and 99 health facility assessments across all sites. Analysis included coding within and across cases, identifying broad themes on recognition of illness, decision-making, and patterns of care seeking, and corresponding contextual factors. Technical support was provided throughout the process for capacity building, quality assurance, and consistency across sites. Conclusion This study provides rigorous evidence on how women and families recognize and respond to maternal and newborn illness. By using a common methodology and tools, findings not only were site-specific but also allow for comparison across contexts.
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- 2017
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12. Summary findings from a mixed methods study on identifying and responding to maternal and newborn illness in seven countries: implications for programs
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Danielle Charlet, Allisyn C. Moran, and Supriya Madhavan
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Maternal mortality ,Newborn mortality ,Developing country ,Qualitative research ,Care-seeking behavior ,Nutritional diseases. Deficiency diseases ,RC620-627 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background There is a lack of systematic information documenting recognition of potentially life-threatening complications and decisions to seek care, as well as reaching care and the specific steps in that process. In response to this gap in knowledge, a multi-country mixed methods study was conducted to illuminate the dynamics driving Delays 1 and 2 across seven countries for maternal and newborn illness and death. Methods A common protocol and tools were developed, adapted by each of seven study teams depending on their local context (Ethiopia, India, Indonesia, Nigeria, Tanzania, Uganda, and Nepal). Maternal and newborn illness, and maternal and newborn death cases were included. Trained interviewers conducted event narratives to elicit and document a detailed sequence of actions, from onset of symptoms to the resolution of the problem. Event timelines were constructed, and in-depth interviews with key informants in the community were conducted. Transcripts were coded and analyzed for common themes corresponding to the three main domains of recognition, decision-making, and care-seeking. Results Maternal symptom recognition and decision-making to seek care is faster than for newborns. Perceived cause of the illness (supernatural vs. biological) influences the type of care sought (spiritual/traditional vs. formal sector, skilled). Mothers, fathers, and other relatives tend to be the decision-makers for newborns while husbands and elder females make decisions for maternal cases. Cultural norms such as confinement periods and perceptions of newborn vulnerability result in care being brought in to the home. Perceived and actual poor quality of care was repeatedly experienced by families seeking care. Conclusion The findings link to three action points: (1) messaging around newborn illness needs to reinforce a sense of urgency and the need for skilled care regardless of perceived cause; (2) targeted awareness building around specific maternal danger signs that are not currently recognized and where quality care is available is needed; and (3) designing appropriate contextualized messages. This research links to and supports a number of current global initiatives such as Ending Preventable Maternal Mortality, the Every Newborn Action Plan, the WHO Quality of Care framework, and the WHO guidelines on simplified management of newborn sepsis at the community level. This type of research is invaluable for designing programs to improve maternal and newborn survival to achieve ambitious global targets.
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- 2017
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13. Institutional maternal and perinatal deaths: a review of 40 low and middle income countries
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Patricia E. Bailey, Wasihun Andualem, Michel Brun, Lynn Freedman, Sourou Gbangbade, Malick Kante, Emily Keyes, Edwin Libamba, Allisyn C. Moran, Halima Mouniri, Dahada Ould el Joud, and Kavita Singh
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Cause of maternal death ,Direct and indirect deaths ,Cause specific case fatality rate ,Stillbirth rate ,Early neonatal death rate ,Perinatal mortality ,Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background Understanding the magnitude and clinical causes of maternal and perinatal mortality are basic requirements for positive change. Facility-based information offers a contextualized resource for clinical and organizational quality improvement. We describe the magnitude of institutional maternal mortality, causes of death and cause-specific case fatality rates, as well as stillbirth and pre-discharge neonatal death rates. Methods This paper draws on secondary data from 40 low and middle income countries that conducted emergency obstetric and newborn care assessments over the last 10 years. We reviewed 6.5 million deliveries, surveyed in 15,411 facilities. Most of the data were extracted from reports and aggregated with excel. Results Hemorrhage and hypertensive diseases contributed to about one third of institutional maternal deaths and indirect causes contributed another third (given the overrepresentation of sub-Saharan African countries with large proportions of indirect causes). The most lethal obstetric complication, across all regions, was ruptured uterus, followed by sepsis in Latin America and the Caribbean and sub-Saharan Africa. Stillbirth rates exceeded pre-discharge neonatal death rates in nearly all countries, possibly because women and their newborns were discharged soon after birth. Conclusions To a large extent, facility-based findings mirror what population-based systematic reviews have also documented. As coverage of a skilled attendant at birth increases, proportionally more deaths will occur in facilities, making improvements in record-keeping and health management information systems, especially for stillbirths and early neonatal deaths, all the more critical.
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- 2017
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14. Countdown to 2015 country case studies: systematic tools to address the 'black box' of health systems and policy assessment
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Neha S. Singh, Luis Huicho, Hoviyeh Afnan-Holmes, Theopista John, Allisyn C. Moran, Tim Colbourn, Chris Grundy, Zoe Matthews, Blerta Maliqi, Matthews Mathai, Bernadette Daelmans, Jennifer Requejo, Joy E. Lawn, and On behalf of the Countdown to 2015 Health Systems and Policies Technical Working Group
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Policy analysis ,Health systems ,Reproductive health ,Newborn health ,Maternal health ,Child health ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Evaluating health systems and policy (HSP) change and implementation is critical in understanding reproductive, maternal, newborn and child health (RMNCH) progress within and across countries. Whilst data for health outcomes, coverage and equity have advanced in the last decade, comparable analyses of HSP changes are lacking. We present a set of novel tools developed by Countdown to 2015 (Countdown) to systematically analyse and describe HSP change for RMNCH indicators, enabling multi-country comparisons. Methods International experts worked with eight country teams to develop HSP tools via mixed methods. These tools assess RMNCH change over time (e.g. 1990–2015) and include: (i) Policy and Programme Timeline Tool (depicting change according to level of policy); (ii) Health Policy Tracer Indicators Dashboard (showing 11 selected RMNCH policies over time); (iii) Health Systems Tracer Indicators Dashboard (showing four selected systems indicators over time); and (iv) Programme implementation assessment. To illustrate these tools, we present results from Tanzania and Peru, two of eight Countdown case studies. Results The Policy and Programme Timeline tool shows that Tanzania’s RMNCH environment is complex, with increased funding and programmes for child survival, particularly primary-care implementation. Maternal health was prioritised since mid-1990s, yet with variable programme implementation, mainly targeting facilities. Newborn health only received attention since 2005, yet is rapidly scaling-up interventions at facility- and community-levels. Reproductive health lost momentum, with re-investment since 2010. Contrastingly, Peru moved from standalone to integrated RMNCH programme implementation, combined with multi-sectoral, anti-poverty strategies. The HSP Tracer Indicators Dashboards show that Peru has adopted nine of 11 policy tracer indicators and Tanzania has adopted seven. Peru costed national RMNCH plans pre-2000, whereas Tanzania developed a national RMNCH plan in 2006 but only costed the reproductive health component. Both countries included all lifesaving RMNCH commodities on their essential medicines lists. Peru has twice the health worker density of Tanzania (15.4 vs. 7.1/10,000 population, respectively), although both are below the 22.8 WHO minimum threshold. Conclusions These are the first HSP tools using mixed methods to systematically analyse and describe RMNCH changes within and across countries, important in informing accelerated progress for ending preventable maternal, newborn and child mortality in the post-2015 era.
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- 2016
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15. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting
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Joy E Lawn, Eric O Ohuma, Ellen Bradley, Lorena Suárez Idueta, Elizabeth Hazel, Yemisrach B Okwaraji, Daniel J Erchick, Judith Yargawa, Joanne Katz, Anne C C Lee, Mike Diaz, Mihretab Salasibew, Jennifer Requejo, Chika Hayashi, Ann-Beth Moller, Elaine Borghi, Robert E Black, Hannah Blencowe, Per Ashorn, Ulla Ashorn, Nigel Klein, G Justus Hofmeyr, Marleen Temmerman, Sufia Askari, Samuel Chakwera, Laith Hussain-Alkhateeb, Alexandra Lewin, Wahyu Retno Mahanani, Emily White Johansson, Tina Lavin, Diana Estevez Fernandez, Giovanna Gatica Domínguez, Ayesha de Costa, Jenny A Cresswell, Julia Krasevec, Allisyn C Moran, Veronica Pingray, Gabriela Cormick, Luz Gibbons, José Belizan, Carlos Guevel, Kara Warrilow, Adrienne Gordon, Vicki Flenady, Jessica Sexton, Harriet Lawford, Enny S. Paixao, Ila Rocha Falcão, Mauricio Lima Barreto, Sarka Lisonkova, Qi Wen, Francisco Mardones, Raúl Caulier-Cisterna, José Acuña, Petr Velebil, Jitka Jirova, Erzsébet Horváth-Puhó, Henrik Toft Sørensen, Luule Sakkeus, Liili Abuladze, Mika Gissler, Maziar Moradi-Lakeh, Mohammad Heidarzadeh, Narjes Khalili, Khalid A. Yunis, Ayah Al Bizri, Pascale Nakad, Shamala Devi Karalasingam, J Ravichandran R Jeganathan, Nurakman binti Baharum, Lorena Suárez-Idueta, Arturo Barranco Flores, Jesus F Gonzalez Roldan, Sonia Lopez Alvarez, Aimée E. van Dijk, Lisa Broeders, Luis Huicho, Hugo G Quezada Pinedo, Kim N Cajachagua-Torres, Rodrigo M Carrillo-Larco, Carla Estefania Tarazona Meza, Wilmer Cristobal Guzman-Vilca, Tawa O. Olukade, Hamdy A. Ali, Fawziya Alyafei, Mai AlQubaisi, Mohamad R Alturk, Ho Yeon Kim, Geum Joon Cho, Neda Razaz, Jonas Söderling, Lucy K Smith, Jennifer J Kurinczuk, Ruth J Matthews, Bradley N Manktelow, Elizabeth S Draper, Alan C Fenton, Estelle Lowry, Neil Rowland, Rachael Wood, Kirsten Monteath, Isabel Pereyra, Gabriella Pravia, Celina Davis, Samantha Clarke, Lee S.F. Wu, Sachiyo Yoshida, Rajiv Bahl, Carlos Grandi, Alain B Labrique, Mabhubur Rashid, Salahuddin Ahmed, Arunangshu D. Roy, Rezwanul Haque, Saijuddin Shaikh, Abdullah H. Baqui, Samir K. Saha, Rasheda Khanam, Sayedur Rahman, Roger Shapiro, Rebecca Zash, Mariângela F. Silveira, Romina Buffarini, Patrick Kolsteren, Carl Lachat, Lieven Huybregts, Dominique Roberfroid, Lingxia Zeng, Zhonghai Zhu, Jianrong He, Xiu Qui, Seifu H. Gebreyesus, Kokeb Tesfamariam, Delayehu Bekele, Grace Chan, Estifanos Baye, Firehiwot Workneh, Kwaku P. Asante, Ellen Boanmah-Kaali, Seth Adu-Afarwuah, Kathryn G. Dewey, Stephaney Gyaase, Blair J. Wylie, Betty R. Kirkwood, Alexander Manu, Ravilla D Thulasiraj, James Tielsch, Ranadip Chowdhury, Sunita Taneja, Giridhara R Babu, Prafulla Shriyan, Kenneth Maleta, Charles Mangani, Sandra Acevedo-Gallegos, Maria J. Rodriguez-Sibaja, Subarna K. Khatry, Steven C. LeClerq, Luke C. Mullany, Fyezah Jehan, Muhammad Ilyas, Stephen J. Rogerson, Holger W. Unger, Rakesh Ghosh, Sabine Musange, Vundli Ramokolo, Wanga Zembe-Mkabile, Marzia Lazzerini, Rishard Mohamed, Dongqing Wang, Wafaie W. Fawzi, Daniel T.R. Minja, Christentze Schmiegelow, Honorati Masanja, Emily Smith, John P.A. Lusingu, Omari A. Msemo, Fathma M. Kabole, Salim N. Slim, Paniya Keentupthai, Aroonsri Mongkolchati, Richard Kajubi, Abel Kakuru, Peter Waiswa, Dilys Walker, Davidson H. Hamer, Katherine E.A. Semrau, Enesia B. Chaponda, R. Matthew Chico, Bowen Banda, Kebby Musokotwane, Albert Manasyan, Jake M. Pry, Bernard Chasekwa, Jean Humphrey, Abu Ahmed Shamim, Parul Christian, Hasmot Ali, Rolf D.W. Klemm, Alan B. Massie, Maithili Mitra, Sucheta Mehra, Kerry J. Schulze, Abu Amed Shamim, Alfred Sommer, Barkat Ullah, Keith P. West, Nazma Begum, Nabidul Haque Chowdhury, Shafiqul Islam, Dipak Kumar Mitra, Abdul Quaiyum, Modiegi Diseko, Joseph Makhema, Yue Cheng, Yixin Guo, Shanshan Yuan, Meselech Roro, Bilal Shikur, Frederick Goddard, Sebastien Haneuse, Bezawit Hunegnaw, Yemane Berhane, Alemayehu Worku, Seyram Kaali, Charles D. Arnold, Darby Jack, Seeba Amenga-Etego, Lisa Hurt, Caitlin Shannon, Seyi Soremekun, Nita Bhandari, Jose Martines, Sarmila Mazumder, Yamuna Ana, Deepa R, Lotta Hallamaa, Juha Pyykkö, Mario I. Lumbreras-Marquez, Claudia E. Mendoza-Carrera, Atiya Hussain, Muhammad Karim, Farzana Kausar, Usma Mehmood, Naila Nadeem, Muhammad Imran Nisar, Muhammad Sajid, Ivo Mueller, Maria Ome-Kaius, Elizabeth Butrick, Felix Sayinzoga, Ilaria Mariani, Willy Urassa, Thor Theander, Phillippe Deloron, Birgitte Bruun Nielsen, Alfa Muhihi, Ramadhani Abdallah Noor, Ib Bygbjerg, Sofie Lykke Moeller, Fahad Aftab, Said M. Ali, Pratibha Dhingra, Usha Dhingra, Arup Dutta, Sunil Sazawal, Atifa Suleiman, Mohammed Mohammed, Saikat Deb, Moses R. Kamya, Miriam Nakalembe, Jude Mulowooz, Nicole Santos, Godfrey Biemba, Julie M. Herlihy, Reuben K. Mbewe, Fern Mweena, Kojo Yeboah-Antwi, Jane Bruce, Daniel Chandramohan, and Andrew Prendergast
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General Medicine - Published
- 2023
16. Maternal health policy environment and the relationship with service utilization in low- and middle-income countries
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Andreea A Creanga, Martin AJ Dohlsten, Elizabeth K Stierman, Allisyn C Moran, Meighan Mary, Elizabeth Katwan, and Blerta Maliqi
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Health Policy ,Public Health, Environmental and Occupational Health - Published
- 2023
17. Assessing the neonatal health policy landscape in low- and middle-income countries: Findings from the 2018 WHO SRMNCAH policy survey
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Meighan Mary, Blerta Maliqi, Elizabeth K Stierman, Martin AJ Dohlsten, Allisyn C Moran, Elizabeth Katwan, and Andreea A Creanga
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Health Policy ,Public Health, Environmental and Occupational Health - Published
- 2023
18. Overcoming blame culture
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F Palestra, Nathalie Roos, AS George, P Doherty, A. Biswas, D Jackson, Louise T Day, Mary V Kinney, A de Jonge, AA Manu, Allisyn C. Moran, Midwifery Science, APH - Personalized Medicine, APH - Quality of Care, Amsterdam Reproduction & Development (AR&D), and Faculteit Medische Wetenschappen/UMCG
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Coronavirus disease 2019 (COVID-19) ,Service delivery framework ,business.industry ,Perinatal Death ,media_common.quotation_subject ,Obstetrics and Gynecology ,Blame ,Maternal Mortality ,Pregnancy ,Perinatal health ,Environmental health ,Pandemic ,Maternal Death ,Humans ,Medicine ,Family ,Female ,Quality of care ,business ,Healthcare system ,Perinatal Deaths ,media_common - Abstract
Maternal and perinatal death surveillance and response (MPDSR) is a health systems process entailing the continuous cycle of identification, notification, and review of maternal and perinatal deaths (Surveillance), followed by actions to improve service delivery and quality of care and Response. Prior to the COVID-19 pandemic, there were an estimated 4.6 million maternal and newborn deaths and stillbirths each year. During the pandemic, maternal and perinatal health outcomes have worsened, especially in low- and middle-income countries, highlighting the urgent need to galvanize MPDSR to end preventable mortality and strengthen health systems.
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- 2022
19. A call for standardised age-disaggregated health data
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Howard S. Friedman, Kathleen Strong, Laura Kann, Jennifer Requejo, Joanna Schellenberg, Andrew Marsh, Jotheeswaran Amuthavalli Thiyagarajan, Elsie Akwara, Anshu Banerjee, Ann Hagell, Somnath Chatterji, Boris I Pavlin, Tyler Porth, Shatha Elnakib, Agbessi Amouzou, Ritu Sadana, Abdisalan M. Noor, B. Jane Ferguson, Regina Guthold, Philippe Glaziou, Laura Fagan, Lara M. E. Vaz, Rich Pereira, Rizwana Siddique, Venkatraman Chandra-Mouli, Cynthia Boschi-Pinto, Peter Azzopardi, Liliana Carvajal, Theresa Diaz, Jeremiah S Dery, Sarah Crofts, Saeed Dastgiri, Julia Fitzner, Eduard Jongstra, Allisyn C. Moran, Bochen Cao, Claudia Hanson, Danzhen You, Melinda K. Munos, Ahmad Reza Hosseinpoor, Ann-Beth Moller, Emmanuel Adebayo, Mike English, John J Aponte Varon, and Alison P Morgan
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medicine.medical_specialty ,Health (social science) ,Demographic profile ,Disease ,Corrections ,Environmental health ,Health care ,Epidemiology ,medicine ,Humans ,Disease management (health) ,Pandemics ,Personal View ,business.industry ,Public health ,Comparability ,COVID-19 ,Sustainable Development ,Psychiatry and Mental health ,Geography ,Child, Preschool ,Life course approach ,Morbidity ,Geriatrics and Gerontology ,Family Practice ,business - Abstract
Summary The 2030 Sustainable Development Goals agenda calls for health data to be disaggregated by age. However, age groupings used to record and report health data vary greatly, hindering the harmonisation, comparability, and usefulness of these data, within and across countries. This variability has become especially evident during the COVID-19 pandemic, when there was an urgent need for rapid cross-country analyses of epidemiological patterns by age to direct public health action, but such analyses were limited by the lack of standard age categories. In this Personal View, we propose a recommended set of age groupings to address this issue. These groupings are informed by age-specific patterns of morbidity, mortality, and health risks, and by opportunities for prevention and disease intervention. We recommend age groupings of 5 years for all health data, except for those younger than 5 years, during which time there are rapid biological and physiological changes that justify a finer disaggregation. Although the focus of this Personal View is on the standardisation of the analysis and display of age groups, we also outline the challenges faced in collecting data on exact age, especially for health facilities and surveillance data. The proposed age disaggregation should facilitate targeted, age-specific policies and actions for health care and disease management.
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- 2022
20. Networks of care to strengthen primary healthcare in resource constrained settings
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Enoch Oti Agyekum, Katherine Kalaris, Blerta Maliqi, Allisyn C Moran, Andrews Ayim, and Sanam Roder-DeWan
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General Medicine - Published
- 2023
21. Changes in the health systems and policy environment for maternal and newborn health, 2008–2018: An analysis of data from 78 low-income and middle-income countries
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Elizabeth K. Stierman, Blerta Maliqi, Meighan Mary, Martin AJ. Dohlsten, Elizabeth Katwan, Allisyn C. Moran, and Andreea A. Creanga
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Health (social science) ,History and Philosophy of Science - Published
- 2023
22. Global, regional, and national estimates and trends in stillbirths from 2000 to 2019: a systematic assessment
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Salome Maswime, Leontine Alkema, Trevor Croft, Miranda J. Fix, Andreea A. Creanga, Kenneth Hill, Emi Suzuki, Simon Cousens, Jon Pedersen, Lucy K Smith, Danzhen You, Lucia Hug, Zhengfan Wang, Hannah Blencowe, Jon Wakefield, Allisyn C. Moran, Victor Gaigbe-Togbe, K.S. Joseph, Anu Mishra, Jennifer Zeitlin, Elizabeth M. McClure, Robert Clive Pattinson, and Dianna M. Blau
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medicine.medical_specialty ,Population ,Pregnancy ,Global health ,medicine ,Humans ,education ,Fetal Death ,reproductive and urinary physiology ,education.field_of_study ,Data collection ,Public health ,Mortality rate ,Obstetrics and Gynecology ,General Medicine ,Articles ,Stillbirth ,medicine.disease ,female genital diseases and pregnancy complications ,Geography ,Annual percentage rate ,Data quality ,Female ,Public Health ,Demography - Abstract
Summary Background Stillbirths are a major public health issue and a sensitive marker of the quality of care around pregnancy and birth. The UN Global Strategy for Women's, Children's and Adolescents’ Health (2016–30) and the Every Newborn Action Plan (led by UNICEF and WHO) call for an end to preventable stillbirths. A first step to prevent stillbirths is obtaining standardised measurement of stillbirth rates across countries. We estimated stillbirth rates and their trends for 195 countries from 2000 to 2019 and assessed progress over time. Methods For a systematic assessment, we created a dataset of 2833 country-year datapoints from 171 countries relevant to stillbirth rates, including data from registration and health information systems, household-based surveys, and population-based studies. After data quality assessment and exclusions, we used 1531 datapoints to estimate country-specific stillbirth rates for 195 countries from 2000 to 2019 using a Bayesian hierarchical temporal sparse regression model, according to a definition of stillbirth of at least 28 weeks’ gestational age. Our model combined covariates with a temporal smoothing process such that estimates were informed by data for country-periods with high quality data, while being based on covariates for country-periods with little or no data on stillbirth rates. Bias and additional uncertainty associated with observations based on alternative stillbirth definitions and source types, and observations that were subject to non-sampling errors, were included in the model. We compared the estimated stillbirth rates and trends to previously reported mortality estimates in children younger than 5 years. Findings Globally in 2019, an estimated 2·0 million babies (90% uncertainty interval [UI] 1·9–2·2) were stillborn at 28 weeks or more of gestation, with a global stillbirth rate of 13·9 stillbirths (90% UI 13·5–15·4) per 1000 total births. Stillbirth rates in 2019 varied widely across regions, from 22·8 stillbirths (19·8–27·7) per 1000 total births in west and central Africa to 2·9 (2·7–3·0) in western Europe. After west and central Africa, eastern and southern Africa and south Asia had the second and third highest stillbirth rates in 2019. The global annual rate of reduction in stillbirth rate was estimated at 2·3% (90% UI 1·7–2·7) from 2000 to 2019, which was lower than the 2·9% (2·5–3·2) annual rate of reduction in neonatal mortality rate (for neonates aged
- Published
- 2021
23. Vaccine implementation factors affecting maternal tetanus immunization in low- and middle-income countries: Results of the Maternal Immunization and Antenatal Care Situational Analysis (MIACSA) project
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L.M. Nic Lochlainn, M. Perut, E. Wootton, Jayani Pathirana, N. Yusuf, Theresa Diaz, M. Ahun, S. Rendell, S. Merten, Joachim Hombach, Carsten Mantel, Allisyn C. Moran, Özge Tunçalp, Nathalie Roos, Philipp Lambach, Michelle L. Giles, and Flor M. Munoz
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Service delivery framework ,Cross-sectional study ,030231 tropical medicine ,LMICs, MIACSA ,Article ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Environmental health ,Service Delivery ,Medicine ,Humans ,030212 general & internal medicine ,Child ,Developing Countries ,Receipt ,Tetanus ,General Veterinary ,General Immunology and Microbiology ,business.industry ,Vaccination ,Public Health, Environmental and Occupational Health ,Infant, Newborn ,Prenatal Care ,medicine.disease ,Maternal Immunization ,Infectious Diseases ,Cross-Sectional Studies ,Immunization ,Workforce ,Molecular Medicine ,Female ,business - Abstract
Objectives To examine the characteristics of existing maternal tetanus immunization programmes for pregnant women in low- and middle-income countries (LMICs) and to identify and understand the challenges, barriers and facilitators associated with maternal vaccine service delivery that may impact the introduction and implementation of new maternal vaccines in the future. Design A mixed methods, cross sectional study with four data collection phases including a desk review, online survey, telephone and face-to-face interviews and in country visits. Setting LMICs. Results The majority of countries (84/95; 88%) had a maternal tetanus immunization policy. Countries with high protection at birth (PAB) were more likely to report tetanus toxoid-containing vaccine (TTCV) coverage targets > 90%. Less than half the countries included in this study had a TTCV coverage target of > 90%. Procurement and distribution of TTCV was nearly always the responsibility of the Expanded Programme on Immunization (EPI), however planning and management of maternal immunization was often shared between EPI and Maternal, Newborn and Child Health (MNCH) programmes. Receipt of TTCV at the same time as the antenatal care visit correlated with high PAB. Most countries (81/95; 85%) had an immunization safety surveillance system in place although only 11% could differentiate an adverse event following immunization (AEFI) in pregnant and non-pregnant women. Conclusions Recommendations arising from the MIACSA project to strengthen existing services currently delivering maternal tetanus immunization in LMICs include establishing and maintaining vaccination targets, clearly defining responsibilities and fostering collaborations between EPI and MNCH, investing in strengthening the health workforce, improving the design and use of existing record keeping for immunization, adjusting current AEFI reporting to differentiate pregnant women and endeavoring to integrate the provision of TTCV within ANC services where appropriate.
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- 2020
24. Maternal Mortality, Stillbirths, and Neonatal Mortality: A Transition Model Based on Analyses of 149 Countries
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Ties Boerma, O. Campbell, Agbessi Amouzou, Cauane Blumenberg, Hannah Blencowe, Allisyn C. Moran, Joy E. Lawn, and Gloria Ikilezi
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- 2022
25. Development of indicators for integrated antenatal care service provision: a feasibility study in Burkina Faso, Kenya, Malawi, Senegal and Sierra Leone
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Ashley Sheffel, Tova Tampe, Elizabeth Katwan, and Allisyn C Moran
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General Medicine - Abstract
ObjectivesWhile service integration has gained prominence as an objective of many global initiatives, there is no widely recognised single definition of integration nor a clear understanding of how programmes are integrated into health systems to achieve improved health outcomes. This study aims to review measurement approaches for integrated antenatal care (ANC) services, propose and operationalise indicators for measuring ANC service integration and inform an integrated ANC indicator recommendation for use in low-income and middle-income countries (LMICs).DesignFeasibility study.SettingBurkina Faso, Kenya, Malawi, Senegal and Sierra Leone.MethodsOur six-step approach included: (1) conceptualise ANC service integration models; (2) conduct a targeted literature review on measurement of ANC service integration; (3) develop criteria for ANC service integration indicators; (4) propose indicators for ANC service integration; (5) use extant data to operationalise the indicators; and (6) synthesise information to make an integrated ANC indicator recommendation for use in LMICs.ResultsGiven the multidimensionality of integration, we outlined three models for conceptualising ANC service integration: integrated health systems, continuity of care and coordinated care. Looking across ANC service integration estimates, there were large differences between estimates for ANC service integration depending on the model used, and in some countries, the ANC integration indicator definition within a model. No one integrated ANC indicator was consistently the highest estimate for ANC service integration. However, continuity of care was consistently the lowest estimate for ANC service integration.ConclusionsIntegrated ANC services are foundational to ensuring universal health coverage. However, our findings demonstrate the complexities in monitoring indicators of ANC service quality using extant data in LMICs. Given the challenges, it is recommended that countries focus on monitoring measures of service quality. In addition, efforts should be made to improve data collection tools and routine health information systems to better capture measures of service integration.
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- 2023
26. Networks of Care: An Approach to Improving Maternal and Newborn Health
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Katherine Kalaris, Emma Radovich, Andy E. Carmone, Jeffrey Michael Smith, Anne Hyre, Martina Lukong Baye, Clemence Vougmo, Anshu Banerjee, Jerker Liljestrand, and Allisyn C. Moran
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Health Policy ,Public Health, Environmental and Occupational Health - Published
- 2022
27. Study protocol for WHO and UNICEF estimates of global, regional, and national preterm birth rates for 2010 to 2019
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Jennifer Requejo, Hannah Blencowe, Ann-Beth Moller, Allisyn C. Moran, Jennifer Cresswell, Joy E Lawn, Laith Hussain-Alkhateeb, Rajiv Bahl, Emily White Johansson, Yemisrach B. Okwaraji, Olufemi T Oladapo, Eric O Ohuma, and Ayesha De Costa
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Databases, Factual ,Maternal Health ,Global Health ,Medical Records ,Study Protocol ,Database and Informatics Methods ,Pregnancy ,Medicine and Health Sciences ,Public and Occupational Health ,Database Searching ,education.field_of_study ,Multidisciplinary ,Mortality rate ,Gestational age ,Obstetrics and Gynecology ,Public Health, Global Health, Social Medicine and Epidemiology ,Medicine ,Premature Birth ,Female ,Live birth ,Infant, Premature ,United Nations ,Death Rates ,Science ,Population ,Gestational Age ,Ballard Maturational Assessment ,World Health Organization ,Preterm Birth ,Research and Analysis Methods ,Birth rate ,Bias ,Population Metrics ,medicine ,Humans ,education ,Population Biology ,business.industry ,Infant, Newborn ,Biology and Life Sciences ,Neonates ,Bayes Theorem ,Birth Rates ,medicine.disease ,Pregnancy Complications ,Epidemiologic Studies ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Birth ,Women's Health ,Observational study ,business ,Demography ,Systematic Reviews as Topic ,Developmental Biology - Abstract
Background Preterm birth is a leading cause of death among children under five years. Previous estimates indicated global preterm birth rate of 10.6% (14.8 million neonates) in 2014. We aim to update preterm birth estimates at global, regional, and national levels for the period 2010 to 2019. Methods Preterm birth is defined as a live birth occurring before 37 completed gestational weeks, or Discussion Accurate measurement of preterm birth is challenging in many countries given incomplete or unavailable data from national administrative sources, compounded by limited gestational age assessment during pregnancy to define preterm birth. Up-to-date modelled estimates will be an important resource to measure the global burden of preterm birth and to inform policies and programs especially in settings with a high burden of neonatal mortality. Trial registration PROSPERO registration: CRD42021237861.
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- 2021
28. Tuberculosis in pregnancy: an estimate of the global burden of disease
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Jordan Sugarman, BSc, Charlotte Colvin, PhD, Allisyn C Moran, PhD, and Dr. Olivia Oxlade, PhD
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Public aspects of medicine ,RA1-1270 - Abstract
Background: The estimated number of maternal deaths in 2013 worldwide was 289 000, a 45% reduction from 1990. Non-obstetric causes such as infectious diseases including tuberculosis now account for 28% of maternal deaths. In 2013, 3·3 million cases of tuberculosis were estimated to occur in women globally. During pregnancy, tuberculosis is associated with poor outcomes, including increased mortality in both the neonate and the pregnant woman. The aim of our study was to estimate the burden of tuberculosis disease among pregnant women, and to describe how maternal care services could be used as a platform to improve case detection. Methods: We used publicly accessible country-level estimates of the total population, distribution of the total population by age and sex, crude birth rate, estimated prevalence of active tuberculosis, and case notification data by age and sex to estimate the number of pregnant women with active tuberculosis for 217 countries. We then used indicators of health system access and tuberculosis diagnostic test performance obtained from published literature to determine how many of these cases could ultimately be detected. Findings: We estimated that 216 500 (95% uncertainty range 192 100–247 000) active tuberculosis cases existed in pregnant women globally in 2011. The greatest burdens were in the WHO African region with 89 400 cases and the WHO South East Asian region with 67 500 cases in pregnant women. Chest radiography or Xpert RIF/MTB, delivered through maternal care services, were estimated to detect as many as 114 100 and 120 300 tuberculosis cases, respectively. Interpretation: The burden of tuberculosis disease in pregnant women is substantial. Maternal care services could provide an important platform for tuberculosis detection, treatment initiation, and subsequent follow-up. Funding: United States Agency for International Development.
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- 2014
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29. The WHO safe childbirth checklist after 5 years: future directions for improving outcomes
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Rose L Molina, Lauren Bobanski, Neelam Dhingra-Kumar, Allisyn C Moran, Ayda Taha, Somesh Kumar, and Katherine E A Semrau
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Pregnancy ,Parturition ,Humans ,Female ,General Medicine ,Delivery, Obstetric ,World Health Organization ,Checklist ,Quality of Health Care - Published
- 2021
30. Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Kizito Shirima, Harriet Ruysen, Josephine Shabani, Nishant Thakur, Qazi Sadeq-ur Rahman, Andrea B. Pembe, Menna Narcis Tarimo, Tazeen Tahsina, Allisyn C. Moran, Kimberly Peven, Joy E Lawn, Rejina Gurung, Louise T Day, and Claudia Hanson
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Adult ,medicine.medical_specialty ,Time Factors ,Coverage ,Adolescent ,Health management systems ,Staffing ,Reproductive medicine ,Uterotonics ,Uterotonic ,Maternal ,lcsh:Gynecology and obstetrics ,Sensitivity and Specificity ,Tanzania ,Validity ,Postpartum haemorrhage ,Young Adult ,Nepal ,Pregnancy ,Hospital records ,Oxytocics ,Surveys and Questionnaires ,Medicine ,Humans ,Registries ,Survey ,lcsh:RG1-991 ,Bangladesh ,biology ,Health management system ,business.industry ,Research ,Postpartum Hemorrhage ,Infant, Newborn ,Obstetrics and Gynecology ,biology.organism_classification ,Hospitals ,Data Accuracy ,Perinatal Care ,Maternal Mortality ,Data quality ,Emergency medicine ,Birth ,Observational study ,Female ,business - Abstract
Background Postpartum haemorrhage (PPH) is a leading cause of preventable maternal mortality worldwide. The World Health Organization (WHO) recommends uterotonic administration for every woman after birth to prevent PPH. There are no standardised data collected in large-scale measurement platforms. The Every Newborn Birth Indicators Research Tracking in Hospitals (EN-BIRTH) is an observational study to assess the validity of measurement of maternal and newborn indicators, and this paper reports findings regarding measurement of coverage and quality for uterotonics. Methods The EN-BIRTH study took place in five hospitals in Bangladesh, Nepal and Tanzania, from July 2017 to July 2018. Clinical observers collected tablet-based, time-stamped data. We compared observation data for uterotonics to routine hospital register-records and women’s report at exit-interview survey. We analysed the coverage and quality gap for timing and dose of administration. The register design was evaluated against gap analyses and qualitative interview data assessing the barriers and enablers to data recording and use. Results Observed uterotonic coverage was high in all five hospitals (> 99%, 95% CI 98.7–99.8%). Survey-report underestimated coverage (79.5 to 91.7%). “Don’t know” replies varied (2.1 to 14.4%) and were higher after caesarean (3.7 to 59.3%). Overall, there was low accuracy in survey data for details of uterotonic administration (type and timing). Register-recorded coverage varied in four hospitals capturing uterotonics in a specific column (21.6, 64.5, 97.6, 99.4%). The average coverage measurement gap was 18.1% for register-recorded and 6.0% for survey-reported coverage. Uterotonics were given to 15.9% of women within the “right time” (1 min) and 69.8% within 3 min. Women’s report of knowing the purpose of uterotonics after birth ranged from 0.4 to 64.9% between hospitals. Enabling register design and adequate staffing were reported to improve routine recording. Conclusions Routine registers have potential to track uterotonic coverage – register data were highly accurate in two EN-BIRTH hospitals, compared to consistently underestimated coverage by survey-report. Although uterotonic coverage was high, there were gaps in observed quality for timing and dose. Standardisation of register design and implementation could improve data quality and data flow from registers into health management information reporting systems, and requires further assessment.
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- 2021
31. Additional file 3 of Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Ruysen, Harriet, Shabani, Josephine, Hanson, Claudia, Day, Louise T., Pembe, Andrea B., Peven, Kimberly, Rahman, Qazi Sadeq-Ur, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Tarimo, Menna Narcis, Allisyn C. Moran, and Lawn, Joy E.
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Additional file 3. STROBE Checklist.
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- 2021
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32. Additional file 15 of Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Ruysen, Harriet, Shabani, Josephine, Hanson, Claudia, Day, Louise T., Pembe, Andrea B., Peven, Kimberly, Rahman, Qazi Sadeq-Ur, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Tarimo, Menna Narcis, Allisyn C. Moran, and Lawn, Joy E.
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Additional file 15. Assessment of routine recording responsibilities for uterotonic provision, EN-BIRTH Study.
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- 2021
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33. Assessment of the validity of the measurement of newborn and maternal health-care coverage in hospitals (EN-BIRTH) : an observational study
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Louise Tina Day, Qazi Sadeq-ur Rahman, Ahmed Ehsanur Rahman, Nahya Salim, Ashish KC, Harriet Ruysen, Tazeen Tahsina, Honorati Masanja, Omkar Basnet, Georgia R Gore-Langton, Sojib Bin Zaman, Josephine Shabani, Anjani Kumar Jha, Vladimir Sergeevich Gordeev, Shafiqul Ameen, Donat Shamba, Bijay Jha, Dorothy Boggs, Tanvir Hossain, Kizito Shirima, Ram Chandra Bastola, Kimberly Peven, Abu Bakkar Siddique, Godfrey Mbaruku, Rajendra Paudel, Angela Baschieri, Aniqa Tasnim Hossain, Stefanie Kong, Asmita Paudel, Anisuddin Ahmed, Simon Cousens, Shams El Arifeen, Joy E Lawn, Florina Serbanescu, Agbessi Amouzou, Johan Ivar Sæbø, Matthews Mathai, Barbara Rawlins, Tariq Azim, Lara Vaz, Jean-Pierre Monet, Debra Jackson, Jennifer Requejo, Pavani K Ram, Allisyn C Moran, Theopista John Kabuteni, Tapas Mazumder, Hafizur Rahman, Ziaul Haque Shaikh, Taqbir Us Samad Talha, Rajib Haider, Aysha Siddika, Taslima Akter Sumi, Jasmin Khan, Bilkish Biswas, M A Mannan, Abu Hasanuzzaman, Ayub Ali, Rowshan Hosne Jahan, Amir Hossain, Ishrat Jahan, Rejina Gurung, Avinash K Sunny, Nishant Thakur, Jagat Jeevan Ghimire, Elisha Joshi, Parashu Ram Shrestha, Shree Krishna Shrestha, Dela Singh, Nisha Rana, Mwifadhi Mrisho, Fatuma Manzi, Claudia Hanson, Edward Kija, Andrea Pembe, Rodrick Kisenge, Karim Manji, Namala Mkopi, Evelyne Assenga, Hannah Blencowe, Sarah G Moxon, and Naresh P KC
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medicine.medical_specialty ,Maternal-Child Health Services ,030231 tropical medicine ,Breastfeeding ,Psychological intervention ,Maternal health care ,Early initiation ,Infant, Newborn, Diseases ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,medicine ,Humans ,030212 general & internal medicine ,Developing Countries ,Quality Indicators, Health Care ,Quality of Health Care ,Obstetrics ,business.industry ,Gold standard ,Postpartum Hemorrhage ,Infant, Newborn ,Reproducibility of Results ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Anti-Bacterial Agents ,Kangaroo-Mother Care Method ,Neonatal infection ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Breast Feeding ,Observational study ,Neonatal death ,business - Abstract
Summary Background Progress in reducing maternal and neonatal deaths and stillbirths is impeded by data gaps, especially regarding coverage and quality of care in hospitals. We aimed to assess the validity of indicators of maternal and newborn health-care coverage around the time of birth in survey data and routine facility register data. Methods Every Newborn-BIRTH Indicators Research Tracking in Hospitals was an observational study in five hospitals in Bangladesh, Nepal, and Tanzania. We included women and their newborn babies who consented on admission to hospital. Exclusion critiera at admission were no fetal heartbeat heard or imminent birth. For coverage of uterotonics to prevent post-partum haemorrhage, early initiation of breastfeeding (within 1 h), neonatal bag-mask ventilation, kangaroo mother care (KMC), and antibiotics for clinically defined neonatal infection (sepsis, pneumonia, or meningitis), we collected time-stamped, direct observation or case note verification data as gold standard. We compared data reported via hospital exit surveys and via hospital registers to the gold standard, pooled using random effects meta-analysis. We calculated population-level validity ratios (measured coverage to observed coverage) plus individual-level validity metrics. Findings We observed 23 471 births and 840 mother–baby KMC pairs, and verified the case notes of 1015 admitted newborn babies regarding antibiotic treatment. Exit-survey-reported coverage for KMC was 99·9% (95% CI 98·3–100) compared with observed coverage of 100% (99·9–100), but exit surveys underestimated coverage for uterotonics (84·7% [79·1–89·5]) vs 99·4% [98·7–99·8] observed), bag-mask ventilation (0·8% [0·4–1·4]) vs 4·4% [1·9–8·1]), and antibiotics for neonatal infection (74·7% [55·3–90·1] vs 96·4% [94·0–98·6] observed). Early breastfeeding coverage was overestimated in exit surveys (53·2% [39·4–66·8) vs 10·9% [3·8–21·0] observed). “Don’t know” responses concerning clinical interventions were more common in the exit survey after caesarean birth. Register data underestimated coverage of uterotonics (77·9% [37·8–99·5] vs 99·2% [98·6–99·7] observed), bag-mask ventilation (4·3% [2·1–7·3] vs 5·1% [2·0–9·6] observed), KMC (92·9% [84·2–98·5] vs 100% [99·9–100] observed), and overestimated early breastfeeding (85·9% (58·1–99·6) vs 12·5% [4·6–23·6] observed). Inter-hospital heterogeneity was higher for register-recorded coverage than for exit survey report. Even with the same register design, accuracy varied between hospitals. Interpretation Coverage indicators for newborn and maternal health care in exit surveys had low accuracy for specific clinical interventions, except for self-report of KMC, which had high sensitivity after admission to a KMC ward or corner and could be considered for further assessment. Hospital register design and completion are less standardised than surveys, resulting in variable data quality, with good validity for the best performing sites. Because approximately 80% of births worldwide take place in facilities, standardising register design and information systems has the potential to sustainably improve the quality of data on care at birth. Funding Children's Investment Fund Foundation and Swedish Research Council.
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- 2021
34. Additional file 1 of Respectful maternal and newborn care: measurement in one EN-BIRTH study hospital in Nepal
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Rejina Gurung, Ruysen, Harriet, Sunny, Avinash K., Day, Louise T., Loveday Penn-Kekana, Målqvist, Mats, Binda Ghimire, Singh, Dela, Omkar Basnet, Srijana Sharma, Shaver, Theresa, Allisyn C. Moran, Lawn, Joy E., and KC, Ashish
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Additional file 1. STROBE checklist.
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- 2021
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35. Additional file 5 of Respectful maternal and newborn care: measurement in one EN-BIRTH study hospital in Nepal
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Rejina Gurung, Ruysen, Harriet, Sunny, Avinash K., Day, Louise T., Loveday Penn-Kekana, Målqvist, Mats, Binda Ghimire, Singh, Dela, Omkar Basnet, Srijana Sharma, Shaver, Theresa, Allisyn C. Moran, Lawn, Joy E., and KC, Ashish
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Additional file 5. Ethical approval of local institutional review boards, EN-BIRTH and NePeriQIP studies.
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- 2021
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36. Additional file 9 of Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Ruysen, Harriet, Shabani, Josephine, Hanson, Claudia, Day, Louise T., Pembe, Andrea B., Peven, Kimberly, Rahman, Qazi Sadeq-Ur, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Tarimo, Menna Narcis, Allisyn C. Moran, and Lawn, Joy E.
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Additional file 9. Individual-level validation of exit-survey report for uterotonic administration, EN-BIRTH Study (n = 23,051).
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- 2021
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37. Additional file 4 of Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Ruysen, Harriet, Shabani, Josephine, Hanson, Claudia, Day, Louise T., Pembe, Andrea B., Peven, Kimberly, Rahman, Qazi Sadeq-Ur, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Tarimo, Menna Narcis, Allisyn C. Moran, and Lawn, Joy E.
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Additional file 4. Data collection dates by site, EN-BIRTH study.
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- 2021
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38. Additional file 5 of Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Ruysen, Harriet, Shabani, Josephine, Hanson, Claudia, Day, Louise T., Pembe, Andrea B., Peven, Kimberly, Rahman, Qazi Sadeq-Ur, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Tarimo, Menna Narcis, Allisyn C. Moran, and Lawn, Joy E.
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Additional file 5. Facility register design and completion approaches for uterotonics by site, EN-BIRTH study (n = 22,002).
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- 2021
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39. Additional file 4 of Respectful maternal and newborn care: measurement in one EN-BIRTH study hospital in Nepal
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Rejina Gurung, Ruysen, Harriet, Sunny, Avinash K., Day, Louise T., Loveday Penn-Kekana, Målqvist, Mats, Binda Ghimire, Singh, Dela, Omkar Basnet, Srijana Sharma, Shaver, Theresa, Allisyn C. Moran, Lawn, Joy E., and KC, Ashish
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Additional file 4. Mode of birth by ethnicity at Pokhara Hospital, Nepal, EN-BIRTH study.
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- 2021
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40. Global, Regional, and National Levels and Trends in Stillbirths from 2000 to 2019: A Systematic Assessment
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Jennifer Zeitlin, Jon Wakefield, Allisyn C. Moran, Hannah Blencowe, Andreea A. Creanga, Kenneth Hill, Robert Clive Pattinson, Jon Pedersen, Anu Mishra, Lucy K Smith, Emi Suzuki, Victor Gaigbe-Togbe, Leontine Alkema, Simon Cousens, K.S. Joseph, Danzhen You, Lucia Hug, Salome Maswime, Zhengfan Wang, Trevor Croft, Miranda J. Fix, Dianna M. Blau, and Elizabeth M. McClure
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Estimation ,medicine.medical_specialty ,education.field_of_study ,Pregnancy ,Data collection ,Mortality rate ,Public health ,Population ,medicine.disease ,female genital diseases and pregnancy complications ,Geography ,Annual percentage rate ,medicine ,Point estimation ,education ,reproductive and urinary physiology ,Demography - Abstract
Background: Stillbirths are a major public health issue and a sensitive marker of the quality of care around pregnancy and birth. The UN Global Strategy for Women’s, Children’s and Adolescents’ Health and the Every Newborn Action Plan (ENAP) call for ending preventable stillbirths. A first step to prevent stillbirths is obtaining standardized measurement of stillbirth levels and trends across countries. We estimated levels and trends in stillbirth rates at 28 weeks or more of gestation from 2000 to 2019 and assessed progress over time. Methods: Our dataset contained 2,800 country-year datapoints from 171 countries relevant to stillbirth rates, including data from registration systems, household-based surveys and population-based studies. We estimated country-specific stillbirth rates for all countries from 2000 to 2019 using a Bayesian hierarchical temporal sparse regression model. Our model combined covariates with a temporal smoothing process such that estimates were informed by data in country-periods with high-quality data and covariate-based for country-periods with limited or no data on stillbirth rates. Bias and additional uncertainty associated with observations using alternative stillbirth definitions, source types and observations that were subject to non-sampling errors were included in the model. Results: In 2019, an estimated 2.0 [90 percent uncertainty interval: 1.9, 2.2] million babies were stillborn at 28 weeks or more of gestation, with a global stillbirth rate of 13.9 [13.5, 15.4] stillbirths per 1,000 total births. Stillbirth rates varied widely across the world from 22.8 [19.8, 27.7] per 1,000 total births in West and Central Africa to 2.9 [2.7, 3.0] per 1,000 total births in Western Europe, with West and Central Africa, Eastern and Southern Africa and South Asia having the highest stillbirth rates in 2019. The global annual rate of reduction in the stillbirth rate was estimated at 2.3 [1.7, 2.7] per cent from 2000 to 2019, lower than the 2.9 [2.5, 3.2] percent reduction in the neonatal mortality rate and the 4.3 [3.8, 4.7] percent reduction in the mortality rate among children aged 1–59 months over the same period. Based on point estimates, 14 countries halved their stillbirth rate since 2000, and 115 countries reduced the stillbirth rate by more than 25 per cent. The remaining 80 countries for which we made estimates reduced their stillbirth rate by less than 25 percent since 2000, with the majority located in Sub-Saharan Africa. Interpretation: in reducing the stillbirth rate has been slow compared with declines in the mortality rate among children under 5 years of age. Accelerated improvements are most needed in the regions and countries with high stillbirth rates, particularly in sub-Saharan Africa where the increases in number of births has outpaced modest progress and declines in stillbirth rates, leading to a stagnation in the number of stillbirths since 2000. Increased efforts are needed to raise public awareness of stillbirths, to improve data collection and to prevent stillbirths. It’s not possible to assess progress going forward or understand public health priorities locally unless there is investment in gathering information about stillbirths. Funding Statement: UNICEF’s stillbirth estimation work was supported by the Bill & Melinda Gates Foundation (OPP1180460 OP190601 and INV-001395). We also acknowledge the Foreign, Commonwealth & Development Office (United Kingdom) for helping to initiate this work. Declaration of Interests: We declare that we have no conflicts of interest.
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- 2021
41. Additional file 3 of Respectful maternal and newborn care: measurement in one EN-BIRTH study hospital in Nepal
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Rejina Gurung, Ruysen, Harriet, Sunny, Avinash K., Day, Louise T., Loveday Penn-Kekana, Målqvist, Mats, Binda Ghimire, Singh, Dela, Omkar Basnet, Srijana Sharma, Shaver, Theresa, Allisyn C. Moran, Lawn, Joy E., and KC, Ashish
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Additional file 3. Background characteristics of women enrolled in NePeriQIP and EN-BIRTH studies.
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- 2021
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42. Additional file 2 of Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Ruysen, Harriet, Shabani, Josephine, Hanson, Claudia, Day, Louise T., Pembe, Andrea B., Peven, Kimberly, Rahman, Qazi Sadeq-Ur, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Tarimo, Menna Narcis, Allisyn C. Moran, and Lawn, Joy E.
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education - Abstract
Additional file 2. Ethical approval of local institutional review boards, EN-BIRTH study.
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- 2021
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43. Additional file 6 of Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study
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Ruysen, Harriet, Shabani, Josephine, Hanson, Claudia, Day, Louise T., Pembe, Andrea B., Peven, Kimberly, Rahman, Qazi Sadeq-Ur, Nishant Thakur, Kizito Shirima, Tazeen Tahsina, Rejina Gurung, Tarimo, Menna Narcis, Allisyn C. Moran, and Lawn, Joy E.
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Additional file 6. Inter-observer agreement for uterotonic administration using Kappa, EN-BIRTH study.
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- 2021
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44. Potential impact of midwives in preventing and reducing maternal and neonatal mortality and stillbirths: a Lives Saved Tool modelling study
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Allisyn C. Moran, Andrea Nove, Maria Najjemba, Ingrid K. Friberg, Petra ten Hoope-Bender, Fran McConville, Sally Tracy, Caroline S.E. Homer, and Luc de Bernis
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Nurse Midwives ,030231 tropical medicine ,Population ,Psychological intervention ,Developing country ,Midwifery ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Environmental health ,Infant Mortality ,Global health ,Medicine ,Humans ,Attrition ,Maternal Health Services ,030212 general & internal medicine ,Human Development Index ,education ,Developing Countries ,education.field_of_study ,Models, Statistical ,business.industry ,lcsh:Public aspects of medicine ,Infant, Newborn ,Infant ,lcsh:RA1-1270 ,Articles ,General Medicine ,Stillbirth ,medicine.disease ,Infant mortality ,Maternal Mortality ,0605 Microbiology, 1117 Public Health and Health Services ,Female ,business ,Adolescent health - Abstract
Summary Background Strengthening the capacity of midwives to deliver high-quality maternal and newborn health services has been highlighted as a priority by global health organisations. To support low-income and middle-income countries (LMICs) in their decisions about investments in health, we aimed to estimate the potential impact of midwives on reducing maternal and neonatal deaths and stillbirths under several intervention coverage scenarios. Methods For this modelling study, we used the Lives Saved Tool to estimate the number of deaths that would be averted by 2035, if coverage of health interventions that can be delivered by professional midwives were scaled up in 88 countries that account for the vast majority of the world's maternal and neonatal deaths and stillbirths. We used four scenarios to assess the effects of increasing the coverage of midwife-delivered interventions by a modest amount (10% every 5 years), a substantial amount (25% every 5 years), and the amount needed to reach universal coverage of these interventions (ie, to 95%); and the effects of coverage attrition (a 2% decrease every 5 years). We grouped countries in three equal-sized groups according to their Human Development Index. Group A included the 30 countries with the lowest HDI, group B included 29 low-to-medium HDI countries, and group C included 29 medium-to-high HDI countries. Findings We estimated that, relative to current coverage, a substantial increase in coverage of midwife-delivered interventions could avert 41% of maternal deaths, 39% of neonatal deaths, and 26% of stillbirths, equating to 2·2 million deaths averted per year by 2035. Even a modest increase in coverage of midwife-delivered interventions could avert 22% of maternal deaths, 23% of neonatal deaths, and 14% of stillbirths, equating to 1·3 million deaths averted per year by 2035. Relative to current coverage, universal coverage of midwife-delivered interventions would avert 67% of maternal deaths, 64% of neonatal deaths, and 65% of stillbirths, allowing 4·3 million lives to be saved annually by 2035. These deaths averted would be particularly concentrated in the group B countries, which currently account for a large proportion of the world's population and have high mortality rates compared with group C. Interpretation Midwives can help to substantially reduce maternal and neonatal mortality and stillbirths in LMICs. However, to realise this potential, midwives need to have skills and competencies in line with recommendations from the International Confederation of Midwives, to be part of a team of sufficient size and skill, and to work in an enabling environment. Our study highlights the potential of midwives but there are many challenges to the achievement of this potential. If increased coverage of midwife-delivered interventions can be achieved, health systems will be better able to provide effective coverage of essential sexual, reproductive, maternal, newborn, and adolescent health interventions. Funding New Venture Fund.
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- 2020
45. Timing and number of antenatal care contacts in low and middle-income countries: Analysis in the Countdown to 2030 priority countries
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Ties Boerma, Lara M. E. Vaz, Allisyn C. Moran, Sanni Yaya, Liliana Carvajal, Jennifer Requejo, Agbessi Amouzou-Aguirre, Youssouf Keita, Safia S Jiwani, and Doris Chou
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Adult ,Asia ,030231 tropical medicine ,Developing country ,Prenatal care ,Odds ,03 medical and health sciences ,Research Theme 1: Countdown Coverage ,0302 clinical medicine ,Health facility ,Pregnancy ,hemic and lymphatic diseases ,Surveys and Questionnaires ,Medicine ,Humans ,030212 general & internal medicine ,Developing Countries ,reproductive and urinary physiology ,Multiple Indicator Cluster Surveys ,business.industry ,Health Policy ,Public Health, Environmental and Occupational Health ,Prenatal Care ,Patient Acceptance of Health Care ,Sustainable Development ,medicine.disease ,Confidence interval ,female genital diseases and pregnancy complications ,Caribbean Region ,Socioeconomic Factors ,Income ,Female ,Health Facilities ,Rural area ,business ,Demography - Abstract
Background The 2016 World Health Organization (WHO) guidelines for antenatal care (ANC) shift the recommended minimum number of ANC contacts from four to eight, specifying the first contact to occur within the first trimester of pregnancy. We quantify the likelihood of meeting this recommendation in 54 Countdown to 2030 priority countries and identify the characteristics of women being left behind. Methods Using 54 Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS) since 2012, we reported the proportion of women with timely ANC initiation and those who received 8-10 contacts by coverage levels of ANC4+ and by Sustainable Development Goal (SDG) regions. We identified demographic, socio-economic and health systems characteristics of timely ANC initiation and achievement of ANC8+. We ran four multiple regression models to quantify the associations between timing of first ANC and the number and content of ANC received. Results Overall, 49.9% of women with ANC1+ and 44.3% of all women had timely ANC initiation; 11.3% achieved ANC8+ and 11.2% received no ANC. Women with timely ANC initiation had 5.2 (95% confidence interval (CI) = 5.0-5.5) and 4.7 (95% CI = 4.4-5.0) times higher odds of receiving four and eight ANC contacts, respectively (P
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- 2020
46. Discordance in postnatal care between mothers and newborns: Measurement artifact or missed opportunity?
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Yaya Sanni, Elizabeth Hazel, Lara M. E. Vaz, Allisyn C. Moran, and Agbessi Amouzou
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Adult ,Postnatal Care ,medicine.medical_specialty ,Concordance ,Child Health Services ,030231 tropical medicine ,Intrapartum care ,Mothers ,Logistic regression ,Research Theme 1: Countdown Coverage ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,medicine ,Humans ,Maternal Health Services ,030212 general & internal medicine ,Demography ,Confusion ,Obstetrics ,business.industry ,Adverse conditions ,Health Policy ,Infant, Newborn ,Public Health, Environmental and Occupational Health ,Prenatal Care ,Health Care Surveys ,Female ,medicine.symptom ,Artifacts ,Missed opportunity ,business - Abstract
Background Postnatal care (PNC) for mothers and newborns is essential to monitor risks of morbidity and adverse conditions following delivery. Current estimates of the coverage of PNC show substantial discordance between mothers and newborns. We investigate the sources of this discordance in Demographic and Health Surveys (DHS). Methods We used DHS data from 48 countries collected since 2011, spanning phases 6 and 7 of the survey program with 32 and 16 surveys, respectively, analyzed. We assessed the distribution of the reported timing of PNC and conducted a sensitivity analysis that excludes/includes PNC reported within 0-1 hour or PNC in the day 2. Agreement in PNC reporting considered four groups: (1) Concordance, neither mother nor newborn received PNC; (2) Concordance, mother and newborn pair received PNC; (3) Discordance, mother received PNC and newborn did not; of (4) Discordance, mother did not receive PNC but the newborn did. We carried out logistic regressions to understand correlates of PNC discordance. All analyses distinguished phase 6 surveys from phase 7. Results We found substantial differences in the PNC coverage estimated between phase 6 and phase 7 surveys. The phase 7 PNC questions for newborns were improved to increase the understanding of the questions by respondent which probably led to reducing the large PNC gap between mothers and newborns observed in phase 6 surveys. With phase 6 surveys, PNC coverage for mother was estimated on average at 62% compared to only 31% for newborns. No such gap was observed for phase 7 surveys, where for both mothers and newborns, the PNC coverage estimate was similar, at 56%. For both phases, over half of the reported PNC for mothers and newborns occurred during 0-1 hour following delivery, leading to substantial overestimation of PNC coverage, due to confusion between intrapartum care and PNC. There were 37% discordant cases between mother and newborn, largely in favor of the mother in phase 6 surveys, compared to 16% in phase 7 surveys. In phase 6 surveys, discordant PNC cases were observed largely among facility deliveries vs non-facility deliveries (44% compared to 19%). Conclusions Current estimates of coverage of PNC from DHS phase 6 surveys appears to include substantial level of measurement noises that could explain substantial part of the mother-newborn discordance in PNC. The PNC estimates appear to capture a substantial number of intrapartum care. Current measurement approaches warrant further validation to ensure accurate monitoring of the PNC programs.
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- 2020
47. What is meant by validity in maternal and newborn health measurement? A conceptual framework for understanding indicator validation
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Claudia Hanson, Ann-Beth Moller, Kathleen Hill, Lenka Benova, Alison Morgan, Shams Al Arifeen, Katherine Semrau, Lara M. E. Vaz, and Allisyn C. Moran
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Research Validity ,Maternal Health ,Applied psychology ,Global Health ,Pediatrics ,Neonatal Care ,Labor and Delivery ,0302 clinical medicine ,Health care ,Medicine and Health Sciences ,Global health ,Public and Occupational Health ,030212 general & internal medicine ,Health Systems Strengthening ,030219 obstetrics & reproductive medicine ,Multidisciplinary ,Obstetrics and Gynecology ,Research Assessment ,Convergent validity ,Medicine ,Psychology ,Research Article ,Death Rates ,Science ,MEDLINE ,Research and Analysis Methods ,Nonprobability sampling ,03 medical and health sciences ,Population Metrics ,Humans ,Infant Health ,Quality Indicators, Health Care ,Health Care Policy ,Population Biology ,business.industry ,Infant, Newborn ,Biology and Life Sciences ,Neonates ,Reproducibility of Results ,Construct validity ,Health indicator ,Health Care ,Conceptual framework ,Birth ,Women's Health ,Neonatology ,Health Statistics ,Morbidity ,business ,Developmental Biology - Abstract
BACKGROUND: Rigorous monitoring supports progress in achieving maternal and newborn mortality and morbidity reductions. Recent work to strengthen measurement for maternal and newborn health highlights the existence of a large number of indicators being used for this purpose. The definitions and data sources used to produce indicator estimates vary and challenges exist with completeness, accuracy, transparency, and timeliness of data. The objective of this study is to create a conceptual overview of how indicator validity is defined and understood by those who develop and use maternal and newborn health indicators. METHODS: A conceptual framework of validity was developed using mixed methods. We were guided by principles for conceptual frameworks and by a review of the literature and key maternal and newborn health indicator guidance documents. We also conducted qualitative semi-structured interviews with 32 key informants chosen through purposive sampling. RESULTS: We categorised indicator validity into three main types: criterion, convergent, and construct. Criterion or diagnostic validity, comparing a measure with a gold standard, has predominantly been used to assess indicators of care coverage and content. Studies assessing convergent validity quantify the extent to which two or more indicator measurement approaches, none of which is a gold-standard, relate. Key informants considered construct validity, or the accuracy of the operationalisation of a concept or phenomenon, a critical part of the overall assessment of indicator validity. CONCLUSION: Given concerns about the large number of maternal and newborn health indicators currently in use, a more consistent understanding of validity can help guide prioritization of key indicators and inform development of new indicators. All three types of validity are relevant for evaluating the performance of maternal and newborn health indicators. We highlight the need to establish a common language and understanding of indicator validity among the various global and local stakeholders working within maternal and newborn health.
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- 2020
48. Antenatal care service delivery and factors affecting effective tetanus vaccine coverage in low- and middle-income countries: results of the Maternal Immunisation and Antenatal Care Situational analysis (MIACSA) project
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Özge Tunçalp, Matthews Mathai, S. Merten, Elizabeth Mason, S. Rendell, Philipp Lambach, Michelle L. Giles, Jayani Pathirana, Joachim Hombach, Allisyn C. Moran, Flor M. Munoz, M. Baye, Nathalie Roos, and Theresa Diaz
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Cross-sectional study ,Service delivery framework ,030231 tropical medicine ,Antenatal care ,MIACSA ,User fee ,Article ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Environmental health ,medicine ,Tetanus Toxoid ,Humans ,030212 general & internal medicine ,Developing Countries ,Disease surveillance ,Tetanus ,General Veterinary ,General Immunology and Microbiology ,business.industry ,Vaccination ,Public Health, Environmental and Occupational Health ,Infant, Newborn ,Prenatal Care ,medicine.disease ,Neonatal tetanus ,Infectious Diseases ,Cross-Sectional Studies ,Tetanus vaccine ,Molecular Medicine ,Female ,Immunization ,business ,medicine.drug - Abstract
Objectives To map the integration of existing maternal tetanus immunization programmes within antenatal care (ANC) services for pregnant women in low- and middle-income countries (LMICs) and to identify and understand the challenges, barriers and facilitators associated with high performance maternal vaccine service delivery. Design A mixed methods, cross sectional study with four data collection phases including a desk review, online survey, telephone and face-to-face interviews and in country visits was undertaken between 2016 and 2018. Associations of different service delivery process components with protection at birth (PAB) and with country groups were established. PAB was defined as the proportion of neonates protected at birth against neonatal tetanus. Regression analysis and structural equation modelling was used to assess associations of different variables with maternal tetanus immunization coverage. Latent class analysis (LCA), was used to group country performance for maternal immunization, and to address the problem of multicollinearity. Setting LMICs. Results The majority of LMICs had a policy on recommended number of ANC visits, however most were yet to implement the WHO guidelines recommending eight ANC contacts. Countries that recommended > 4 ANC contacts were more likely to have high PAB > 90%. Passive disease surveillance was the most common form of disease surveillance performed but the maternal and neonatal morbidity and mortality indicators recorded differed between countries. The presence of user fees for antenatal care and maternal immunization was significantly associated with lower PAB ( Conclusions Recommendations include implementing the current WHO ANC guideline to facilitate increased opportunities for vaccination during each pregnancy. Improved utilisation of ANC services by increasing the demand side by increasing the quality of services, reducing any associated costs and supporting user fee exemptions, or the supply side can also enhance utilisation of ANC services which are positioned as an ideal platform for delivery of maternal vaccines.
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- 2020
49. Data Collection Tools for Maternal and Child Health in Humanitarian Emergencies: An Updated Systematic Review
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Fernanda Dias Romeiro, Theresa Diaz, Allisyn C. Moran, Cynthia Boschi-Pinto, and Juliana Lima Constantino
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Medical education ,Data collection ,Maternal-Child Health Services ,Maternal and child health ,030503 health policy & services ,Data Collection ,Public Health, Environmental and Occupational Health ,Plan (drawing) ,Relief Work ,Child health ,World health ,03 medical and health sciences ,0302 clinical medicine ,Humans ,Maternal health ,030212 general & internal medicine ,0305 other medical science ,Psychology ,Key workers - Abstract
The worst rates of preventable mortality and morbidity among women and children occur in humanitarian settings. Reliable, easy-to-use, standardized, and efficient tools for data collection are needed to enable different organizations to plan and act in the most effective way. In 2015, the World Health Organization (WHO) commissioned a review of tools for data collection on the health of women and children in humanitarian emergencies. An update of this review was conducted to investigate whether the recommendations made were taken forward and to identify newly developed tools. Fifty-three studies and 5 new tools were identified. Only 1 study used 1 of the tools identified in our search. Little has been done in terms of the previous recommendations. Authors may not be aware of the availability of such tools and of the importance of documenting their data using the same methods as other researchers. Currently used tools may not be suitable for use in humanitarian settings or may not include the domains of the authors’ interests. The development of standardized instruments should be done with all key workers in the area and could be coordinated by the WHO.
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- 2019
50. Exploring the feasibility of establishing a core set of sexual, reproductive, maternal, newborn, child and adolescent health indicators in humanitarian settings: a multimethods, multicountry qualitative study protocol
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Loulou Hassan Kobeissi, Manizha Ashna, Kassandre Messier, Allisyn C Moran, Lale Say, Kathleen Louise Strong, and Angel Foster
- Subjects
Adolescent ,statistics & research methods ,Adolescent Health ,Infant, Newborn ,sexual medicine ,General Medicine ,Global Health ,Observational Studies as Topic ,Reproductive Health ,Feasibility Studies ,Humans ,Female ,Reproductive Health Services ,Sexual Health ,Child ,reproductive medicine - Abstract
IntroductionIn 2019, over 70 million people were forcibly displaced worldwide. Women and girls comprise nearly half of this population and are at heightened risk of negative sexual and reproductive health outcomes. With the collapse of health systems, reduced resources and increased vulnerabilities from displacement, there is a need to strengthen current practices and ensure the delivery of comprehensive sexual, reproductive, maternal, newborn, child and adolescent health (SRMNCAH) services. Recognising the need for consistency in data collection, analysis and use, the WHO developed a list of core SRMNCAH monitoring and evaluation indicators for services and outcomes in humanitarian settings. This research will explore the feasibility of collecting this core set of SRMNCAH indicators in displacement contexts.Methods and analysisWe will undertake a multimethods qualitative study in seven humanitarian settings: Afghanistan, Albania, Bangladesh, Cameroon, the Democratic Republic of the Congo, Iraq and Jordan. We selected sites that reflect diversity in geographic region, sociocultural characteristics, primary location(s) of displaced persons and nature and phase of the crisis. Our study consists of four components: key informant interviews, facility assessments, observational sessions at select facilities and focus group discussions with front-line healthcare personnel. We will analyse our data using descriptive statistics and for content and themes. We will begin by analysing data from each setting separately and will then combine these data to explore concordant and discordant results, triangulate findings and develop global recommendations.Ethics and disseminationThe University of Ottawa’s Research Ethics Board and the Research Project Review Panel (RP 2) of the World Health Organization-Department of Sexual and Reproductive Health as well as local IRBs of PIs’ research institutions reviewed and approved this protocol. We intend to disseminate findings through workshops at the WHO country, regional and headquarter levels, as well as through local, national and international conferences, workshops, peer-reviewed publications, and reports.
- Published
- 2021
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