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1. Differences in Skin Cancer Rates by Transplanted Organ Type and Patient Age After Organ Transplant in White Patients

Author: Lee Wheless, Nimay Anand, Allison Hanlon, and Mary-Margaret Chren
Subjects: Cohort Studies, Skin Neoplasms, Risk Factors, Incidence, Humans, Dermatology, Organ Transplantation, White People, Transplant Recipients, Retrospective Studies
Abstract: ImportanceAlthough it is known that patients with thoracic organ transplants develop skin cancer more frequently than those who receive nonthoracic organ transplants, patterns of risk for subsequent skin cancers are unknown.ObjectiveTo further characterize organ transplant recipients who develop multiple skin cancers and assess for patterns of development of additional skin cancers beyond the first skin cancer diagnosis by patient age and transplanted organ type.Design, Setting, and ParticipantsThis cohort study used validated electronic health record–based data from a single tertiary care academic medical center to identify 5129 solid organ transplant recipients who underwent transplant surgery between 1992 and 2017 and were older than 18 years at the time of transplant. The cohort was limited to White patients because they have the highest skin cancer risk based on phenotype. The mean follow-up was 6.6 years. Data were analyzed June 9, 2021, to May 31, 2022.Main Outcomes and MeasuresDifferences in rates of skin cancer development for first and subsequent skin cancers were measured using t test or analysis of variance and χ2 tests for continuous and categorical variables. Rates of skin cancer development were compared based on organ type and patient age at transplant using Fine-Gray tests and cumulative incidence plots.ResultsA total of 5129 organ transplant recipients (mean [SD] age, 51.3 [12.9] years; 3287 men [64.1%]) were included. Of these, 695 patients (13.6%) had development of at least 1 skin cancer, with 6842 skin cancers identified in the cohort overall. Compared with liver transplant recipients, heart, lung, or kidney recipients were more likely to develop at least 1 skin cancer (χ2 test, 25.6; df, 4; P 2 test, 20.4; df, 4; P 2 test, 10.9; df, 4; P Conclusions and RelevanceThis cohort study found that there was no difference by organ type for development of subsequent skin cancers in organ transplant recipients, and recipients of all organ types developed additional skin cancers at high rates after the initial skin cancer.
Published: 2023

2. Characteristics of Lower Extremity Infection Rates Following Mohs Micrographic Surgery

Author: Lee Wheless, Allison Hanlon, Eva B. Niklinska, and Alexander Hicks
Subjects: Male, medicine.medical_specialty, Skin Neoplasms, Wound size, Dermatology, Micrographic surgery, medicine, Humans, Surgical Wound Infection, University medical, Medical history, Antibiotic prophylaxis, Retrospective Studies, business.industry, fungi, General Medicine, Antibiotic Prophylaxis, Mohs Surgery, Surgery, Increased risk, Lower Extremity, Female, Complication, business, Surgical site infection
Abstract: BACKGROUND Surgical site infection (SSI) is the most common complication for Mohs micrographic surgery (MMS). Lower extremity surgical sites are at an increased risk for developing SSI. OBJECTIVE This study aimed to evaluate lower extremity SSI rates post-MMS based on closure type and antibiotic usage. MATERIALS AND METHODS A retrospective review was performed of all lower extremity MMS cases from 2011 to 2016 at Vanderbilt University Medical Center. Patient history, surgical details, and follow-up appointments were reviewed. RESULTS Six hundred twenty MMS lower extremity surgeries were eligible. Review identified an overall lower extremity SSI rate of 7.4%. Infection rates were significantly increased in wound closed by flaps/grafts (p < .001). Although wound size and preoperative antibiotic prophylaxis were initially associated with increased infection rate (p = .03, p = .015), the associations were fully attenuated when adjusting for closure type. CONCLUSION More complicated repair techniques (flap/graft) for larger wound sizes contribute to increased SSI risk among lower extremity MMS cases. Providers can use this information to guide antibiotic prophylaxis.
Published: 2021

3. Development of a core outcome set for basal cell carcinoma

Author: Daniel I. Schlessinger, Kelly A. Reynolds, McKenzie A. Dirr, Sarah A. Ibrahim, Arianna F. Yanes, Jake M. Lazaroff, Victoria Godinez-Puig, Brian R. Chen, Anastasia O. Kurta, Jill K. Cotseones, Sarah G. Chiren, Karina C. Furlan, Sanjana Iyengar, Ramona Behshad, Danielle M. DeHoratius, Pablo Denes, Aaron M. Drucker, Leonard M. Dzubow, Jeremy R. Etzkorn, Catherine A. Harwood, John Y.S. Kim, Naomi Lawrence, Erica H. Lee, Gary S. Lissner, Ashfaq A. Marghoob, Rubeta N. Matin, Adam R. Mattox, Bharat B. Mittal, J. Regan Thomas, Xiaolong Alan Zhou, David Zloty, Jochen Schmitt, Jamie J. Kirkham, April W. Armstrong, Nicole Basset-Seguin, Elizabeth M. Billingsley, Jeremy S. Bordeaux, Jerry Brewer, Marc Brown, Mariah Brown, Scott A.B. Collins, Maria Concetta Fargnoli, Sergio Jobim De Azevedo, Reinhard Dummer, Alexander Eggermont, Glenn D. Goldman, Merete Haedersdal, Elizabeth K. Hale, Allison Hanlon, Kelly L. Harms, Conway C. Huang, Eva A. Hurst, Gino K. In, Nicole Kelleners-Smeets, Meenal Kheterpal, Barry Leshin, Michel Mcdonald, Stanley J. Miller, Alexander Miller, Eliot N. Mostow, Myrto Trakatelli, Kishwer S. Nehal, Desiree Ratner, Howard Rogers, Kavita Y. Sarin, Seaver L. Soon, Thomas Stasko, Paul A. Storrs, Luca Tagliaferri, Allison T. Vidimos, Sandra L. Wong, Siegrid S. Yu, Iris Zalaudek, Nathalie C. Zeitouni, John A. Zitelli, Emily Poon, Joseph F. Sobanko, Todd V. Cartee, Ian A. Maher, Murad Alam, Schlessinger, Daniel I, Reynolds, Kelly A, Dirr, McKenzie A, Ibrahim, Sarah A, Yanes, Arianna F, Lazaroff, Jake M, Godinez-Puig, Victoria, Chen, Brian R, Kurta, Anastasia O, Cotseones, Jill K, Chiren, Sarah G, Furlan, Karina C, Iyengar, Sanjana, Behshad, Ramona, Dehoratius, Danielle M, Denes, Pablo, Drucker, Aaron M, Dzubow, Leonard M, Etzkorn, Jeremy R, Harwood, Catherine A, Kim, John Y S, Lawrence, Naomi, Lee, Erica H, Lissner, Gary S, Marghoob, Ashfaq A, Matin, Rubeta N, Mattox, Adam R, Mittal, Bharat B, Thomas, J Regan, Zhou, Xiaolong Alan, Zloty, David, Schmitt, Jochen, Kirkham, Jamie J, Armstrong, April W, Basset-Seguin, Nicole, Billingsley, Elizabeth M, Bordeaux, Jeremy S, Brewer, Jerry, Brown, Marc, Brown, Mariah, Collins, Scott A B, Fargnoli, Maria Concetta, De Azevedo, Sergio Jobim, Dummer, Reinhard, Eggermont, Alexander, Goldman, Glenn D, Haedersdal, Merete, Hale, Elizabeth K, Hanlon, Allison, Harms, Kelly L, Huang, Conway C, Hurst, Eva A, In, Gino K, Kelleners-Smeets, Nicole, Kheterpal, Meenal, Leshin, Barry, Mcdonald, Michel, Miller, Stanley J, Miller, Alexander, Mostow, Eliot N, Trakatelli, Myrto, Nehal, Kishwer S, Ratner, Desiree, Rogers, Howard, Sarin, Kavita Y, Soon, Seaver L, Stasko, Thoma, Storrs, Paul A, Tagliaferri, Luca, Vidimos, Allison T, Wong, Sandra L, Yu, Siegrid S, Zalaudek, Iri, Zeitouni, Nathalie C, Zitelli, John A, Poon, Emily, Sobanko, Joseph F, Cartee, Todd V, Maher, Ian A, Alam, Murad, Dermatologie, MUMC+: MA Dermatologie (9), and RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy
Subjects: Skin Neoplasms, Delphi Technique, skin cancer, core, Dermatology, measure, Treatment Outcome, basal cell carcinoma, Carcinoma, Basal Cell, Research Design, Quality of Life, outcome, Humans, set
Abstract: Background: There is variation in the outcomes reported in clinical studies of basal cell carcinoma. This can prevent effective meta-analyses from answering important clinical questions. Objective: To identify a recommended minimum set of core outcomes for basal cell carcinoma clinical trials. Methods: Patient and professional Delphi process to cull a long list, culminating in a consensus meeting. To be provisionally accepted, outcomes needed to be deemed important (score, 7-9, with 9 being the maximum) by 70% of each stakeholder group. Results: Two hundred thirty-five candidate outcomes identified via a systematic literature review and survey of key stakeholders were reduced to 74 that were rated by 100 health care professionals and patients in 2 Delphi rounds. Twenty-seven outcomes were provisionally accepted. The final core set of 5 agreed-upon outcomes after the consensus meeting included complete response; persistent or serious adverse events; recurrence-free survival; quality of life; and patient satisfaction, including cosmetic outcome. Limitations: English-speaking patients and professionals rated outcomes extracted from English language studies. Conclusion: A core outcome set for basal cell carcinoma has been developed. The use of relevant measures may improve the utility of clinical research and the quality of therapeutic guidance available to clinicians.
Published: 2022

4. Topical and Intralesional Modalities for Actinic Keratoses and Nonmelanoma Skin Cancer in Transplant Recipients

Author: Allison Hanlon, Stacy McMurray, and Lee Wheless
Subjects: medicine.medical_specialty, Modalities, business.industry, medicine, Actinic keratoses, Skin cancer, medicine.disease, business, Dermatology
Published: 2021

5. Anatomy

Author: Allison Hanlon
Published: 2021

6. Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines

Author: Allison Hanlon, Timothy Patton, Christina L. Chung, Selim M. Arcasoy, Jenny Hu, Gavin Hickey, Rade Tomic, David G. Brodland, Garrett R. Roll, Nicolae Leca, Daniel F. Dilling, Jorge M. Mallea, Sarah T. Arron, Don Hayes, Sarah A. Myers, Norah A. Terrault, Daniel Berg, Mark Wigger, Alice L. Gray, Sofya Tokman, Lauren D. Crow, David A. Baran, Faramarz H. Samie, Matthew C. Fox, Erika D. Lease, Marcy Neuburg, James C. Lee, Bryan T. Carroll, Anokhi Jambusaria-Pahlajani, Robert Samuel Hopkins, A. Emtiazjoo, Milan J. Anadkat, William Black, Rajiv I. Nijhawan, John A. Carucci, Karthik Ranganna, Melissa Bleicher, John R. Griffin, Seaver L. Soon, Amanda R. Twigg, Jonathan E. Holtz, Alan Menter, Rehana L. Ahmed, Christie P. Thomas, Ramsey R. Hachem, Travis W. Blalock, Elizabeth M. Billingsley, Justin J. Leitenberger, Amit D. Parulekar, Teresa Soriano, George Chaux, Conway C. Huang, Shang I Brian Jiang, Vishal A. Patel, Jennifer A. Stein, Mark Abdelmalek, Clark C. Otley, So Yeon Paek, Timothy W. Chang, Manisha J. Patel, Ashwin K. Ravichandran, Jonathan P. Singer, Siddhartha G. Kapnadak, Alden M. Doyle, Shahid M. Malik, Shelley A. Hall, Kristin Bibee, Mariah Brown, Simin Goral, Daniel C. Brennan, Pooja Singh, Edward S. Kraus, Nathalie C. Zeitouni, Carrie Ann Cusack, Maria Isabel Longo, Douglas J. Norman, Rachel Redenius, Stefan E. Lowenstein, Ronald A. Squires, Sandra J. Taler, Thomas Stasko, Nkanyezi H. Ferguson, Mary Ann Lim, Thuzar M. Shin, Melissa Pugliano-Mauro, and Scott W. Fosko
Subjects: African american, Transplantation, medicine.medical_specialty, Skin cancer screening, integumentary system, business.industry, Delphi method, Expert consensus, 030230 surgery, medicine.disease, Malignancy, 03 medical and health sciences, 0302 clinical medicine, Medicine, 030211 gastroenterology & hepatology, Transplant patient, Skin cancer, business, Intensive care medicine, Solid organ transplantation
Abstract: Skin cancer is the most common malignancy affecting solid organ transplant recipients (SOTR), and SOTR experience increased skin cancer-associated morbidity and mortality. There are no formal multidisciplinary guidelines for skin cancer screening after transplant, and current practices are widely variable. We conducted three rounds of Delphi method surveys with a panel of 84 U.S. dermatologists and transplant physicians to establish skin cancer screening recommendations for SOTR. The transplant team should risk stratify SOTR for screening, and dermatologists should perform skin cancer screening by full-body skin examination. SOTR with a history of skin cancer should continue regular follow-up with dermatology for skin cancer surveillance. High-risk transplant patients include thoracic organ recipients, SOTR age 50 and above, and male SOTR. High-risk Caucasian patients should be screened within 2 years after transplant, all Caucasian, Asian, Hispanic, and high-risk African American patients should be screened within 5 years after transplant. No consensus was reached regarding screening for low-risk African American SOTR. We propose a standardized approach to skin cancer screening in SOTR based on multidisciplinary expert consensus. These guidelines prioritize and emphasize the need for screening for SOTR at greatest risk for skin cancer.
Published: 2019

7. Consensus-Based Recommendations on the Prevention of Squamous Cell Carcinoma in Solid Organ Transplant Recipients A Delphi Consensus Statement

Author: Nathalie C. Zeitouni, Thomas Stasko, Sara J. Li, Emőke Rácz, Syed N. Shah, Catherine A. Harwood, Seaver L. Soon, Stephen Shumack, Alvin H Chong, Justin J. Leitenberger, Chrysalyne D. Schmults, Allison Hanlon, Manisha J. Loss, Petter Gjersvik, Elisa Zavattaro, Begoña Escutia-Muñoz, R. Samuel Hopkins, Thuzar M. Shin, Matthew C. Fox, Faramarz H. Samie, Charlotte M. Proby, Sarah A. Myers, Jennifer A. Desimone, Carla Ferrándiz-Pulido, Katie Blasdale, Walmar R. P. Oliveira, Sarah T. Arron, José M. Mascaró, Jan Nico Bouwes Bavinck, Günther F.L. Hofbauer, Veronica Ruiz-Salas, Edit B. Olasz Harken, Travis W. Blalock, Sean R. Christensen, Elizabeth M. Billingsley, Bichchau Nguyen, Véronique Del Marmol, John A. Carucci, Maryam M. Asgari, Fiona O. Zwald, Christina L. Chung, Deniz Seçkin, Roel E. Genders, Clark C. Otley, Paul R. Massey, Emilie Ducroux, Bryan T. Carroll, Alexandra Geusau, and Anokhi Jambusaria-Pahlajani
Subjects: medicine.medical_specialty, Skin Neoplasms, Delphi Technique, medicine.medical_treatment, Concordance, Delphi method, MEDLINE, NONMELANOMA SKIN-CANCER, Cryotherapy, Dermatology, Article, DOUBLE-BLIND, medicine, Humans, MULTIPLE ACTINIC KERATOSES, 5-PERCENT IMIQUIMOD, Stage (cooking), IMMUNOSUPPRESSION, business.industry, Actinic keratosis, Organ Transplantation, medicine.disease, Transplant Recipients, RANDOMIZED-TRIAL, Clinical trial, Keratosis, Actinic, REDUCTION, Family medicine, Carcinoma, Squamous Cell, Skin cancer, TOPICAL PHOTODYNAMIC THERAPY, BOWENS-DISEASE, business, CREAM
Abstract: IMPORTANCE There is a paucity of evidence to guide physicians regarding prevention strategies for cutaneous squamous cell carcinoma (CSCC) in solid organ transplant recipients (SOTRs). OBJECTIVE To examine the development and results of a Delphi process initiated to identify consensus-based medical management recommendations for prevention of CSCC in SOTRs. EVIDENCE REVIEW Dermatologists with more than 5 years' experience treating SOTRs were invited to participate. A novel actinic damage and skin cancer index (AD-SCI), consisting of 6 ordinal stages corresponding to an increasing burden of actinic damage and CSCC, was used to guide survey design. Three sequential web-based surveys were administered from January 1, 2019, to December 31, 2020. Pursuant to Delphi principles, respondents thoroughly reviewed all peer responses between rounds. Supplemental questions were also asked to better understand panelists' rationale for their responses. FINDINGS The Delphi panel comprised 48 dermatologists. Respondents represented 13 countries, with 27 (56%) from the US. Twenty-nine respondents (60%) were Mohs surgeons. Consensus was reached with 80% or higher concordance among respondents when presented with a statement, question, or management strategy pertaining to prevention of CSCC in SOTRs. A near-consensus category of 70% to less than 80% concordance was also defined. The AD-SCI stage-based recommendations were established if consensus or near-consensus was achieved. The panel was able to make recommendations for 5 of 6 AD-SCI stages. Key recommendations include the following: cryotherapy for scattered actinic keratosis (AK); field therapy for AK when grouped in 1 anatomical area, unless AKs are thick in which case field therapy and cryotherapy were recommended; combination lesion directed and field therapy with fluorouracil for field cancerized skin; and initiation of acitretin therapy and discussion of immunosuppression reduction or modification for patients who develop multiple skin cancers at a high rate (10 CSCCs per year) or develop high-risk CSCC (defined by a tumor with approximately >= 20% risk of nodal metastasis). No consensus recommendation was achieved for SOTRs with a first low risk CSCC. CONCLUSIONS AND RELEVANCE Physicians may consider implementation of panel recommendations for prevention of CSCC in SOTRs while awaiting high-level-of-evidence data. Additional clinical trials are needed in areas where consensus was not reached.
Published: 2021

8. Somatic Mutation Profile of Atypical Fibroxanthoma and Cutaneous Undifferentiated Pleomorphic Sarcoma

Author: Jonathan L. Levinsohn, Anjela Galan, Young H. Lim, Keith A. Choate, Allison Hanlon, and Theodore Zaki
Subjects: Male, Pathology, medicine.medical_specialty, Skin Neoplasms, Loss of Heterozygosity, Dermatology, Biology, Loss of heterozygosity, Germline mutation, Exome Sequencing, medicine, Xanthomatosis, Humans, Exome sequencing, Aged, Aged, 80 and over, Extramural, Atypical fibroxanthoma, Sarcoma, General Medicine, medicine.disease, Cutaneous Undifferentiated Pleomorphic Sarcoma, Mutation (genetic algorithm), Mutation, Surgery, Tumor Suppressor Protein p53
Published: 2020

9. Development of Phenotyping Algorithms for the Identification of Organ Transplant Recipients: Cohort Study

Author: Laura X. Baker, Nimay Anand, Lee Wheless, Allison Hanlon, Mary-Margaret Chren, Kelly A. Birdwell, and L.D. Edwards
Subjects: medicine.medical_specialty, Original Paper, phenotyping, business.industry, Computer applications to medicine. Medical informatics, R858-859.7, Health Informatics, electronic health record, 030230 surgery, Biobank, Organ transplantation, Random forest, 03 medical and health sciences, Identification (information), 0302 clinical medicine, Health Information Management, Electronic health record, Current Procedural Terminology, Medicine, 030212 general & internal medicine, Extreme gradient boosting, business, Algorithm, organ transplant recipients, Cohort study
Abstract: Background Studies involving organ transplant recipients (OTRs) are often limited to the variables collected in the national Scientific Registry of Transplant Recipients database. Electronic health records contain additional variables that can augment this data source if OTRs can be identified accurately. Objective The aim of this study was to develop phenotyping algorithms to identify OTRs from electronic health records. Methods We used Vanderbilt’s deidentified version of its electronic health record database, which contains nearly 3 million subjects, to develop algorithms to identify OTRs. We identified all 19,817 individuals with at least one International Classification of Diseases (ICD) or Current Procedural Terminology (CPT) code for organ transplantation. We performed a chart review on 1350 randomly selected individuals to determine the transplant status. We constructed machine learning models to calculate positive predictive values and sensitivity for combinations of codes by using classification and regression trees, random forest, and extreme gradient boosting algorithms. Results Of the 1350 reviewed patient charts, 827 were organ transplant recipients while 511 had no record of a transplant, and 12 were equivocal. Most patients with only 1 or 2 transplant codes did not have a transplant. The most common reasons for being labeled a nontransplant patient were the lack of data (229/511, 44.8%) or the patient being evaluated for an organ transplant (174/511, 34.1%). All 3 machine learning algorithms identified OTRs with overall >90% positive predictive value and >88% sensitivity. Conclusions Electronic health records linked to biobanks are increasingly used to conduct large-scale studies but have not been well-utilized in organ transplantation research. We present rigorously evaluated methods for phenotyping OTRs from electronic health records that will enable the use of the full spectrum of clinical data in transplant research. Using several different machine learning algorithms, we were able to identify transplant cases with high accuracy by using only ICD and CPT codes.
Published: 2020

10. Search for direct top squark pair production in events with one lepton, jets, and missing transverse momentum at 13 TeV with the CMS experiment

Author: Sirunyan, A. M. Tumasyan, A. Adam, W. Ambrogi, F. and Bergauer, T. Brandstetter, J. Dragicevic, M. Eroe, J. and Del Valle, A. Escalante Flechl, M. Fruehwirth, R. Jeitler, M. Krammer, N. Kraetschmer, I Liko, D. Madlener, T. and Mikulec, I Rad, N. Schieck, J. Schoefbeck, R. Spanring, M. Spitzbart, D. Waltenberger, W. Wulz, C-E Zarucki, M. and Drugakov, V Mossolov, V Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Di Croce, D. Janssen, X. Lelek, A. and Pieters, M. Sfar, H. Rejeb Van Haevermaet, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. Chhibra, S. S. De Clercq, J. Lontkovskyi, D. Lowette, S. Marchesini, I Moortgat, S. Python, Q. Skovpen, K. and Tavernier, S. Van Doninck, W. Van Mulders, P. Beghin, D. and Bilin, B. Brun, H. Clerbaux, B. De Lentdecker, G. and Delannoy, H. Dorney, B. Favart, L. Grebenyuk, A. Kalsi, A. K. Popov, A. Postiau, N. Starling, E. Thomas, L. and Vander Velde, C. Vanlaer, P. Vannerom, D. Cornelis, T. and Dobur, D. Khvastunov, I Niedziela, M. Roskas, C. Tytgat, M. Verbeke, W. Vermassen, B. Vit, M. Bondu, O. and Bruno, G. Caputo, C. David, P. Delaere, C. Delcourt, M. and Giammanco, A. Lemaitre, V Prisciandaro, J. Saggio, A. and Marono, M. Vidal Vischia, P. Zobec, J. Alves, F. L. and Alves, G. A. Correia Silva, G. Hensel, C. Moraes, A. and Rebello Teles, P. Belchior Batista Das Chagas, E. Carvalho, W. and Chinellato, J. Coelho, E. Da Costa, E. M. Da Silveira, G. G. De Jesus Damiao, D. De Oliveira Martins, C. Fonseca De Souza, S. Huertas Guativa, L. M. Malbouisson, H. Martins, J. and Matos Figueiredo, D. Medina Jaime, M. Melo De Almeida, M. and Herrera, C. Mora Mundim, L. Nogima, H. Prado Da Silva, W. L. Sanchez Rosas, L. J. Santoro, A. Sznajder, A. and Thiel, M. Tonelli Manganote, E. J. Torres Da Silva De Araujo, F. and Vilela Pereira, A. Bernardes, C. A. Calligaris, L. and Fernandez Perez Tomei, T. R. Gregores, E. M. Lemos, D. S. and Mercadante, P. G. Novaes, S. F. Padula, Sandra S. and Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. and Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. and Bonchev, M. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. and Petkov, P. Fang, W. Gao, X. Yuan, L. Chen, G. M. and Chen, H. S. Chen, M. Jiang, C. H. Leggat, D. Liao, H. and Liu, Z. Spiezia, A. Tao, J. Yazgan, E. Zhang, H. and Zhang, S. Zhao, J. Agapitos, A. Ban, Y. Chen, G. and Levin, A. Li, J. Li, L. Li, Q. Qian, S. J. Wang, D. and Wang, Q. Ahmad, M. Hu, Z. Wang, Y. Xiao, M. and Avila, C. Cabrera, A. Florez, C. Gonzalez Hernandez, C. F. and Segura Delgado, M. A. Mejia Guisao, J. Ruiz Alvarez, J. D. and Salazar Gonzalez, C. A. Vanegas Arbelaez, N. Godinovic, N. and Lelas, D. Puljak, I Sculac, T. Antunovic, Z. Kovac, M. Brigljevic, V Ferencek, D. Kadija, K. Mesic, B. and Roguljic, M. Starodumov, A. Susa, T. Ather, M. W. and Attikis, A. Erodotou, E. Ioannou, A. Kolosova, M. and Konstantinou, S. Mavromanolakis, G. Mousa, J. Nicolaou, C. and Ptochos, F. Razis, P. A. Rykaczewski, H. Tsiakkouri, D. and Finger, M. Fingera, Jr., M. Kveton, A. Tomsa, J. and Ayala, E. Carrera Jarrin, E. Assran, Y. Elgammal, S. and Bhowmik, S. De Oliveira, A. Carvalho Antunes Dewanjee, R. K. and Ehataht, K. Kadastik, M. Raidal, M. Veelken, C. Eerola, P. Forthomme, L. Kirschenmann, H. Osterberg, K. and Voutilainen, M. Garcia, F. Havukainen, J. Heikkila, J. K. and Karimaki, V Kim, M. S. Kinnunen, R. Lampen, T. and Lassila-Perini, K. Laurila, S. Lehti, S. Linden, T. and Luukka, P. Maenpaa, T. Siikonen, H. Tuominen, E. and Tuominiemi, J. Tuuva, T. Besancon, M. Couderc, F. and Dejardin, M. Denegri, D. Fabbro, B. Faure, J. L. Ferri, F. Ganjour, S. Givernaud, A. Gras, P. de Monchenault, G. Hamel Jarry, P. Leloup, C. Lenzi, B. Locci, E. and Malcles, J. Rander, J. Rosowsky, A. Sahin, M. O. and Savoy-Navarro, A. Titov, M. Yu, G. B. Ahuja, S. and Amendola, C. Beaudette, F. Busson, P. Charlot, C. Diab, B. Falmagne, G. de Cassagnac, R. Granier Kucher, I and Lobanov, A. Perez, C. Martin Nguyen, M. Ochando, C. and Paganini, P. Rembser, J. Salerno, R. Sauvan, J. B. and Sirois, Y. Zabi, A. Zghiche, A. Agram, J-L Andrea, J. and Bloch, D. Bourgatte, G. Brom, J-M Chabert, E. C. and Collard, C. Conte, E. Fontaine, J-C Gele, D. Goerlach, U. Jansova, M. Le Bihan, A-C Tonon, N. Van Hove, P. and Gadrat, S. Beauceron, S. Bernet, C. Boudoul, G. Camen, C. Carle, A. Chanon, N. Chierici, R. Contardo, D. and Depasse, P. El Mamouni, H. Fay, J. Gascon, S. and Gouzevitch, M. Ille, B. Jain, Sa Lagarde, F. Laktineh, I. B. Lattaud, H. Lesauvage, A. Lethuillier, M. and Mirabito, L. Perries, S. Sordini, V Torterotot, L. and Touquet, G. Vander Donckt, M. Viret, S. Toriashvili, T. and Tsamalaidze, Z. Autermann, C. Feld, L. Kiesel, M. K. and Klein, K. Lipinski, M. Meuser, D. Pauls, A. Preuten, M. and Rauch, M. P. Schulz, J. Teroerde, M. Wittmer, B. and Erdmann, M. Fischer, B. Ghosh, S. Hebbeker, T. Hoepfner, K. Keller, H. Mastrolorenzo, L. Merschmeyer, M. Meyer, A. Millet, P. Mocellin, G. Mondal, S. Mukherjee, S. and Noll, D. Novak, A. Pook, T. Pozdnyakov, A. Quast, T. and Radziej, M. Rath, Y. Reithler, H. Roemer, J. Schmidt, A. and Schuler, S. C. Sharma, A. Wiedenbeck, S. Zaleski, S. and Fluegge, G. Ahmad, W. Haj Hlushchenko, O. Kress, T. and Mueller, T. Nowack, A. Pistone, C. Pooth, O. Roy, D. and Sert, H. Stahl, A. Martin, M. Aldaya Asmuss, P. and Babounikau, I Bakhshiansohi, H. Beernaert, K. Behnke, O. and Martinez, A. Bermudez Bertsche, D. Bin Anuar, A. A. Borras, K. Botta, V Campbell, A. Cardini, A. Connor, P. and Rodriguez, S. Consuegra Contreras-Campana, C. Danilov, V De Wit, A. Defranchis, M. M. Pardos, C. Diez Damiani, D. Dominguez Eckerlin, G. Eckstein, D. Eichhorn, T. Elwood, A. Eren, E. Gallo, E. Geiser, A. Grohsjean, A. and Guthoff, M. Haranko, M. Harb, A. Jafari, A. Jomhari, N. Z. Jung, H. Kasem, A. Kasemann, M. Kaveh, H. and Keaveney, J. Kleinwort, C. Knolle, J. Kruecker, D. and Lange, W. Lenz, T. Lidrych, J. Lipka, K. 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Cooper, I, S. Henderson, C. Rumerio, P. and West, C. Albert, A. Arcaro, D. Demiragli, Z. Gastler, D. and Richardson, C. Rohlf, J. Sperka, D. Suarez, I Sulak, L. Zou, D. Benelli, G. Burkle, B. Coubez, X. Cutts, D. Duh, Y. T. Hadley, M. Heintz, U. Hogan, J. M. and Kwok, K. H. M. Laird, E. Landsberg, G. Lau, K. T. and Narain, M. Sagir, S. Syarif, R. Usai, E. Wong, W. Y. and Yu, D. Zhang, W. Band, R. Brainerd, C. Breedon, R. and Sanchez, M. Calderon De La Barca Chertok, M. Conway, J. and Conway, R. Cox, P. T. Erbacher, R. Flores, C. Funk, G. and Jensen, F. Ko, W. Kukral, O. Lander, R. Mulhearn, M. and Pellett, D. Pilot, J. Shi, M. Taylor, D. Tos, K. and Tripathi, M. Wang, Z. Zhang, F. Bachtis, M. Bravo, C. and Cousins, R. Dasgupta, A. Florent, A. Hauser, J. and Ignatenko, M. Mccoll, N. Nash, W. A. Regnard, S. and Saltzberg, D. Schnaible, C. Stone, B. Valuev, V. Burt, K. Chen, Y. Clare, R. Gary, J. W. Shirazi, S. M. A. Ghiasi Hanson, G. Karapostoli, G. Kennedy, E. Long, O. R. Negrete, M. Olmedo Paneva, I, M. Si, W. Wang, L. and Wimpenny, S. Yates, B. R. Zhang, Y. Branson, J. G. and Cittolin, S. Cooperstein, S. Deelen, N. Derdzinski, M. and Gerosa, R. Gilbert, D. Hashemi, B. Klein, D. Krutelyov, V Letts, J. Masciovecchio, M. Padhi, S. Pieri, M. and Sharma, V Tadel, M. Wurthwein, F. Yagil, A. Della Porta, G. Zevi Amin, N. Bhandari, R. Campagnari, C. Citron, M. and Dutta, V Sevilla, M. Franco Incandela, J. Marsh, B. and Mei, H. Ovcharova, A. Qu, H. Richman, J. Sarica, U. and Stuart, D. Wang, S. Anderson, D. Bornheim, A. Cerri, O. and Dutta, I Lawhorn, J. M. Lu, N. Newman, H. B. Nguyen, T. Q. Pata, J. Spiropulu, M. Vlimant, J. R. Xie, S. and Zhang, Z. Zhu, R. Y. Andrews, M. B. Ferguson, T. and Mudholkar, T. Paulini, M. Sun, M. Vorobiev, I Weinberg, M. Cumalat, J. P. Ford, W. T. MacDonald, E. Mulholland, T. Patel, R. Perloff, A. Stenson, K. Ulmer, K. A. and Wagner, S. R. Alexander, J. Cheng, Y. Chu, J. Datta, A. and Frankenthal, A. Mcdermott, K. Patterson, J. R. 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Strobbe, N. Taylor, L. Tkaczyk, S. Tran, V, N. Uplegger, L. Vaandering, E. W. Vernieri, C. Vidal, R. Wang, M. Weber, H. A. Acosta, D. Avery, P. Bourilkov, D. Brinkerhoff, A. Cadamuro, L. Carnes, A. and Cherepanov, V Errico, F. Field, R. D. Gleyzer, V, S. and Guerrero, D. Joshi, B. M. Kim, M. Konigsberg, J. and Korytov, A. H Lo, K. Ma, P. Matchev, K. Menendez, N. and Mitselmakher, G. Rosenzweig, D. Shi, K. Wang, J. Zuo, X. and Joshi, Y. R. Adams, T. Askew, A. Hagopian, S. and Hagopian, V Johnson, K. F. Khurana, R. Kolberg, T. and Martinez, G. Perry, T. Prosper, H. Schiber, C. Yohay, R. and Zhang, J. Baarmand, M. M. Hohlmann, M. Noonan, D. and Rahmani, M. Saunders, M. Yumiceva, F. Adams, M. R. and Apanasevich, L. Betts, R. R. Cavanaugh, R. Chen, X. and Dittmer, S. Evdokimov, O. Gerber, C. E. Hangal, D. A. and Hofman, D. J. Jung, K. Mills, C. Roy, T. Tonjes, M. B. and Varelas, N. Viinikainen, J. Wang, H. Wang, X. Wu, Z. and Alhusseini, M. Bilki, B. Clarida, W. Dilsiz, K. and Durgut, S. Gandrajula, R. P. Haytmyradov, M. Khristenko, V and Koseyan, O. K. Merlo, J-P Mestvirishvili, A. Moeller, A. and Nachtman, J. Ogul, H. Onel, Y. Ozok, F. Penzo, A. and Snyder, C. Tiras, E. Wetzel, J. Blumenfeld, B. and Cocoros, A. Eminizer, N. Gritsan, V, A. Hung, W. T. and Kyriacou, S. Maksimovic, P. Roskes, J. Swartz, M. and Barrera, C. Baldenegro Baringer, P. Bean, A. Boren, S. and Bowen, J. Bylinkin, A. Isidori, T. Khalil, S. King, J. and Krintiras, G. Kropivnitskaya, A. Lindsey, C. Majumder, D. Mcbrayer, W. Minafra, N. Murray, M. Rogan, C. and Royon, C. Sanders, S. Schmitz, E. Takaki, J. D. Tapia and Williams, J. Wilson, G. Duric, S. Ivanov, A. Kaadze, K. and Kim, D. Maravin, Y. Mendis, D. R. Mitchell, T. and Modak, A. Mohammadi, A. Rebassoo, F. Wright, D. Baden, A. Baron, O. Belloni, A. Eno, S. C. Feng, Y. Hadley, N. J. Jabeen, S. Jeng, G. Y. Kellogg, R. G. Kunkle, J. and Mignerey, A. C. Nabili, S. Ricci-Tam, F. Shin, Y. H. and Skuja, A. Tonwar, S. C. Wong, K. Abercrombie, D. Allen, B. Baty, A. Bi, R. Brandt, S. Busza, W. Cali, I. A. and Ceballos, G. Gomez Goncharov, M. Harris, P. Hsu, D. and Hu, M. Klute, M. Kovalskyi, D. Lee, Y-J Luckey, P. D. and Maier, B. Marini, A. C. Mcginn, C. Mironov, C. and Narayanan, S. Niu, X. Paus, C. Rankin, D. Roland, C. and Roland, G. Shi, Z. Stephans, G. S. F. Sumorok, K. Tatar, K. Velicanu, D. Wang, T. W. Wyslouch, B. Chatterjee, R. M. Evans, A. Guts, S. Hansen, P. Hiltbrand, J. Jain, Sh Kubota, Y. Lesko, Z. Mans, J. Revering, M. and Rusack, R. Saradhy, R. Schroeder, N. Wadud, M. A. and Acosta, J. G. Oliveros, S. Bloom, K. Claes, D. R. and Fangmeier, C. Finco, L. Golf, F. Kamalieddin, R. and Kravchenko, I Siado, J. E. Snow, G. R. Stieger, B. Tabb, W. Agarwal, G. Harrington, C. Iashvili, I. Kharchilava, A. McLean, C. Nguyen, D. Parker, A. Pekkanen, J. and Rappoccio, S. Roozbahani, B. Alverson, G. Barberis, E. and Freer, C. Haddad, Y. Hortiangtham, A. Madigan, G. and Marzocchi, B. Morse, D. M. Orimoto, T. Skinnari, L. and Tishelman-Charny, A. Wamorkar, T. Wang, B. Wisecarver, A. and Wood, D. Bueghly, J. Gunter, T. Hahn, K. A. Odell, N. Schmitt, M. H. Sung, K. Trovato, M. Velasco, M. and Bucci, R. Dev, N. Goldouzian, R. Hildreth, M. Anampa, K. Hurtado Jessop, C. Karmgard, D. J. Lannon, K. Li, W. and Loukas, N. Marinelli, N. Mcalister, I Meng, F. Mueller, C. Musienko, Y. Planer, M. Ruchti, R. Siddireddy, P. and Smith, G. Taroni, S. Wayne, M. Wightman, A. Wolf, M. and Woodard, A. Alimena, J. Bylsma, B. Durkin, L. S. and Francis, B. Hill, C. Ji, W. Lefeld, A. Ling, T. Y. and Winer, B. L. Dezoort, G. Elmer, P. Hardenbrook, J. and Haubrich, N. Higginbotham, S. Kalogeropoulos, A. Kwan, S. and Lange, D. Lucchini, M. T. Luo, J. Marlow, D. Mei, K. and Ojalvo, I Olsen, J. Palmer, C. Piroue, P. Stickland, D. Tully, C. Norberg, S. Barker, A. Barnes, V. E. and Gutay, L. Jones, M. Jung, A. W. Khatiwada, A. Mahakud, B. Miller, D. H. Negro, G. Neumeister, N. Peng, C. C. and Piperov, S. Qiu, H. Schulte, J. F. Trevisani, N. and Wang, F. Xiao, R. Xie, W. Cheng, T. Dolen, J. and Parashar, N. Behrens, U. Ecklund, K. M. Freed, S. and Geurts, F. J. M. Kilpatrick, M. Kumar, Arun Padley, B. P. and Redjimi, R. Roberts, J. Rorie, J. Shi, W. Leiton, A. G. Stahl Tu, Z. Zhang, A. Bodek, A. de Barbaro, P. and Demina, R. Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. Garcia-Bellido, A. Hindrichs, O. Khukhunaishvili, A. and Ranken, E. Taus, R. Chiarito, B. Chou, J. P. Gandrakota, A. Gershtein, Y. Halkiadakis, E. Hart, A. Heindl, M. and Hughes, E. Kaplan, S. Laflotte, I Lath, A. Montalvo, R. and Nash, K. Osherson, M. Saka, H. Salur, S. Schnetzer, S. Somalwar, S. Stone, R. Thomas, S. Acharya, H. and Delannoy, A. G. Spanier, S. Bouhali, O. Dalchenko, M. De Mattia, M. Delgado, A. Dildick, S. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Luo, S. Malhotra, S. Marley, D. Mueller, R. Overton, D. Pernie, L. Rathjens, D. and Safonov, A. Akchurin, N. Damgov, J. De Guio, F. Hegde, V and Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. and Peltola, T. Undleeb, S. Volobouev, I Whitbeck, A. and Greene, S. Gurrola, A. Janjam, R. Johns, W. Maguire, C. and Melo, A. Ni, H. Padeken, K. Romeo, F. Sheldon, P. and Tuo, S. Velkovska, J. Verweij, M. Arenton, M. W. and Barria, P. Cox, B. Cummings, G. Hakala, J. Hirosky, R. and Joyce, M. Ledovskoy, A. Neu, C. Tannenwald, B. and Wolfe, E. Xia, F. Harr, R. Karchin, P. E. Poudyal, N. and Sturdy, J. Thapa, P. Bose, T. Buchanan, J. Caillol, C. Carlsmith, D. Dasu, S. De Bruyn, I Dodd, L. and Galloni, C. He, H. Herndon, M. Herve, A. Hussain, U. and Klabbers, P. Lanaro, A. Loeliger, A. Long, K. Loveless, R. Sreekala, J. Madhusudanan Pinna, D. Ruggles, T. and Savin, A. Smith, W. H. Teague, D. Trembathreichert, S. and Woods, N. CMS Collaboration CMS Collaboration CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: A search for direct top squark pair production is presented. The search is based on proton-proton collision data at a center-of-mass energy of 13 TeV recorded by the CMS experiment at the LHC during 2016, 2017, and 2018, corresponding to an integrated luminosity of 137 fb(-1). The search is carried out using events with a single isolated electron or muon, multiple jets, and large transverse momentum imbalance. The observed data are consistent with the expectations from standard model processes. Exclusions are set in the context of simplified top squark pair production models. Depending on the model, exclusion limits at 95% confidence level for top squark masses up to 1.2 TeV are set for a massless lightest supersymmetric particle, assumed to be the neutralino. For models with top squark masses of 1 TeV, neutralino masses up to 600 GeV are excluded.
Published: 2020

11. The Business of Dermatology

Author: Kavita Mariwalla, Wendy Lewis, Nazanin Saedi, Jill Waibel, James D. Kelso, Cynthia Forbush, Christine E. Foley, Kim Campbell, Joseph K. Francis, E. Victor Ross, Mariah R. Brown, Eileen L. Axibal, Curtis Asbury, Laura Kruter, Misha Zarbafian, Merrick D. Elias, Lauren Taglia, Chloe Gianatasio, Peter A. Lio, Susan H. Weinkle, Elizabeth K. Hale, Heather D. Rogers, Chad L. Prather, Jessica Awerman, Kenneth A. Arndt, Heather Hamilton, Neal Bhatia, Robin Travers, Camile A. Silva, Abel Torres, Amy Derick, Matthew J. Elias, David A. Rubin, Sailesh Konda, Aleksandra Lindgren, Daniel I. Wasserman, Michelle Henry, Joel Schlessinger, Ellen Marmur, Jordan V. Wang, Murad Alam, Keith LeBlanc, Nikki D.Y. Tang, Kathleen M. Welsh, Girish S. Munavalli, Jeffrey S. Orringer, Allison Hanlon, Michael T. Goldfarb, Michael S. Kaminer, Jusleen Ahluwalia, David B. Chaffin, Brooke A. Jackson, Alessia C. Bertucci, Mona A. Gohara, Sarah Sawyer, David J. Goldberg, Deirdre Hooper, Sara Hogan, Rajiv Nijhawan, Briana Paiewonsky, Colton Nielson, Sarah Jackson, Anthony M. Rossi, Omer Ibrahim, Kyle Kieffer, Edward (Ted) Lain, Vince Bertucci, Byron K. Ho, Aleksandra G. Florek, Doris Day, George J. Hruza, Daniel I. Schlessinger, Annie Chiu, Jeffrey S. Dover, Reena Jogi, Elizabeth L. Tanzi, and Gabriel J. Martinez-Diaz
Subjects: medicine.medical_specialty, business.industry, Medicine, business, Dermatology
Published: 2020

12. Mixed higher-order anisotropic flow and nonlinear response coefficients of charged particles in PbPb collisions at root s(NN)=2.76 and 5.02 TeV

Author: Sirunyan, A. M. Tumasyan, A. Adam, W. Ambrogi, F. and Bergauer, T. Brandstetter, J. Dragicevic, M. Eroe, J. and Del Valle, A. Escalante Flechl, M. Fruehwirth, R. Jeitler, M. Krammer, N. Kraetschmer, I Liko, D. Madlener, T. and Mikulec, I Rad, N. Schieck, J. Schoefbeck, R. Spanring, M. Spitzbart, D. Waltenberger, W. Wulz, C-E Zarucki, M. and Drugakov, V Mossolov, V Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Di Croce, D. Janssen, X. Lelek, A. and Pieters, M. Sfar, H. Rejeb Van Haevermaet, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. Chhibra, S. S. De Clercq, J. Lontkovskyi, D. Lowette, S. Marchesini, I Moortgat, S. Python, Q. Skovpen, K. and Tavernier, S. Van Doninck, W. Van Mulders, P. Beghin, D. and Bilin, B. Brun, H. Clerbaux, B. De Lentdecker, G. and Delannoy, H. Dorney, B. Favart, L. Grebenyuk, A. Kalsi, A. K. Popov, A. Postiau, N. Starling, E. Thomas, L. and Vander Velde, C. Vanlaer, P. Vannerom, D. Cornelis, T. and Dobur, D. Khvastunov, I Niedziela, M. Roskas, C. Tytgat, M. Verbeke, W. Vermassen, B. Vit, M. Bondu, O. and Bruno, G. Caputo, C. David, P. Delaere, C. Delcourt, M. and Giammanco, A. Lemaitre, V Prisciandaro, J. Saggio, A. and Marono, M. Vidal Vischia, P. Zobec, J. Alves, F. L. and Alves, G. A. Correia Silva, G. Hensel, C. Moraes, A. and Rebello Teles, P. Belchior Batista Das Chagas, E. Carvalho, W. and Chinellato, J. Coelho, E. Da Costa, E. M. Da Silveira, G. G. De Jesus Damiao, D. De Oliveira Martins, C. Fonseca De Souza, S. Huertas Guativa, L. M. Malbouisson, H. Martins, J. and Matos Figueiredo, D. Medina Jaime, M. Melo De Almeida, M. and Herrera, C. Mora Mundim, L. Nogima, H. Prado Da Silva, W. L. Sanchez Rosas, L. J. Santoro, A. Sznajder, A. and Thiel, M. Tonelli Manganote, E. J. Torres Da Silva De Araujo, F. and Vilela Pereira, A. Bernardes, C. A. Calligaris, L. and Fernandez Perez Tomei, T. R. Gregores, E. M. Lemos, D. S. and Mercadante, P. G. Novaes, S. F. Padula, Sandra S. and Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. and Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. and Bonchev, M. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. and Petkov, P. Fang, W. Gao, X. Yuan, L. Chen, G. M. and Chen, H. S. Chen, M. Jiang, C. H. Leggat, D. Liao, H. and Liu, Z. Spiezia, A. Tao, J. Yazgan, E. Zhang, H. and Zhang, S. Zhao, J. Agapitos, A. Ban, Y. Chen, G. and Levin, A. Li, J. Li, L. Li, Q. Qian, S. J. Wang, D. and Wang, Q. Ahmad, M. Hu, Z. Wang, Y. Xiao, M. and Avila, C. Cabrera, A. Florez, C. Gonzalez Hernandez, C. F. and Segura Delgado, M. A. Mejia Guisao, J. Ruiz Alvarez, J. D. and Salazar Gonzalez, C. A. Vanegas Arbelaez, N. Godinovic, N. and Lelas, D. Puljak, I Sculac, T. Antunovic, Z. Kovac, M. Brigljevic, V Ferencek, D. Kadija, K. Mesic, B. and Roguljic, M. Starodumov, A. Susa, T. Ather, M. W. and Attikis, A. Erodotou, E. Ioannou, A. Kolosova, M. and Konstantinou, S. Mavromanolakis, G. Mousa, J. Nicolaou, C. and Ptochos, F. 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Olmedo Paneva, I, M. Si, W. Wang, L. and Wimpenny, S. Yates, B. R. Zhang, Y. Branson, J. G. and Cittolin, S. Cooperstein, S. Deelen, N. Derdzinski, M. and Gerosa, R. Gilbert, D. Hashemi, B. Klein, D. Krutelyov, V Letts, J. Masciovecchio, M. Padhi, S. Pieri, M. and Sharma, V Tadel, M. Wurthwein, F. Yagil, A. Della Porta, G. Zevi Amin, N. Bhandari, R. Campagnari, C. Citron, M. and Dutta, V Sevilla, M. Franco Incandela, J. Marsh, B. and Mei, H. Ovcharova, A. Qu, H. Richman, J. Sarica, U. and Stuart, D. Wang, S. Anderson, D. Bornheim, A. Cerri, O. and Dutta, I Lawhorn, J. M. Lu, N. Newman, H. B. Nguyen, T. Q. Pata, J. Spiropulu, M. Vlimant, J. R. Xie, S. and Zhang, Z. Zhu, R. Y. Andrews, M. B. Ferguson, T. and Mudholkar, T. Paulini, M. Sun, M. Vorobiev, I Weinberg, M. Cumalat, J. P. Ford, W. T. MacDonald, E. Mulholland, T. Patel, R. Perloff, A. Stenson, K. Ulmer, K. A. and Wagner, S. R. Alexander, J. Cheng, Y. Chu, J. Datta, A. and Frankenthal, A. Mcdermott, K. Patterson, J. R. 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Strobbe, N. Taylor, L. Tkaczyk, S. Tran, V, N. Uplegger, L. Vaandering, E. W. Vernieri, C. Vidal, R. Wang, M. Weber, H. A. Acosta, D. Avery, P. Bourilkov, D. Brinkerhoff, A. Cadamuro, L. Carnes, A. and Cherepanov, V Errico, F. Field, R. D. Gleyzer, V, S. and Guerrero, D. Joshi, B. M. Kim, M. Konigsberg, J. and Korytov, A. H Lo, K. Ma, P. Matchev, K. Menendez, N. and Mitselmakher, G. Rosenzweig, D. Shi, K. Wang, J. Zuo, X. and Joshi, Y. R. Adams, T. Askew, A. Hagopian, S. and Hagopian, V Johnson, K. F. Khurana, R. Kolberg, T. and Martinez, G. Perry, T. Prosper, H. Schiber, C. Yohay, R. and Zhang, J. Baarmand, M. M. Hohlmann, M. Noonan, D. and Rahmani, M. Saunders, M. Yumiceva, F. Adams, M. R. and Apanasevich, L. Betts, R. R. Cavanaugh, R. Chen, X. and Dittmer, S. Evdokimov, O. Gerber, C. E. Hangal, D. A. and Hofman, D. J. Jung, K. Mills, C. Roy, T. Tonjes, M. B. and Varelas, N. Viinikainen, J. Wang, H. Wang, X. Wu, Z. and Alhusseini, M. Bilki, B. Clarida, W. Dilsiz, K. and Durgut, S. 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Allen, B. Baty, A. Bi, R. Brandt, S. Busza, W. Cali, I. A. and Ceballos, G. Gomez Goncharov, M. Harris, P. Hsu, D. and Hu, M. Klute, M. Kovalskyi, D. Lee, Y-J Luckey, P. D. and Maier, B. Marini, A. C. Mcginn, C. Mironov, C. and Narayanan, S. Niu, X. Paus, C. Rankin, D. Roland, C. and Roland, G. Shi, Z. Stephans, G. S. F. Sumorok, K. Tatar, K. Velicanu, D. Wang, T. W. Wyslouch, B. Chatterjee, R. M. Evans, A. Guts, S. Hansen, P. Hiltbrand, J. Jain, Sh Kubota, Y. Lesko, Z. Mans, J. Revering, M. and Rusack, R. Saradhy, R. Schroeder, N. Wadud, M. A. and Acosta, J. G. Oliveros, S. Bloom, K. Claes, D. R. and Fangmeier, C. Finco, L. Golf, F. Kamalieddin, R. and Kravchenko, I Siado, J. E. Snow, G. R. Stieger, B. Tabb, W. Agarwal, G. Harrington, C. Iashvili, I. Kharchilava, A. McLean, C. Nguyen, D. Parker, A. Pekkanen, J. and Rappoccio, S. Roozbahani, B. Alverson, G. Barberis, E. and Freer, C. Haddad, Y. Hortiangtham, A. Madigan, G. and Marzocchi, B. Morse, D. M. Orimoto, T. 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Schulte, J. F. Trevisani, N. and Wang, F. Xiao, R. Xie, W. Cheng, T. Dolen, J. and Parashar, N. Behrens, U. Ecklund, K. M. Freed, S. and Geurts, F. J. M. Kilpatrick, M. Kumar, Arun Padley, B. P. and Redjimi, R. Roberts, J. Rorie, J. Shi, W. Leiton, A. G. Stahl Tu, Z. Zhang, A. Bodek, A. de Barbaro, P. and Demina, R. Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. Garcia-Bellido, A. Hindrichs, O. Khukhunaishvili, A. and Ranken, E. Taus, R. Chiarito, B. Chou, J. P. Gandrakota, A. Gershtein, Y. Halkiadakis, E. Hart, A. Heindl, M. and Hughes, E. Kaplan, S. Laflotte, I Lath, A. Montalvo, R. and Nash, K. Osherson, M. Saka, H. Salur, S. Schnetzer, S. Somalwar, S. Stone, R. Thomas, S. Acharya, H. and Delannoy, A. G. Spanier, S. Bouhali, O. Dalchenko, M. De Mattia, M. Delgado, A. Dildick, S. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Luo, S. Malhotra, S. Marley, D. Mueller, R. Overton, D. Pernie, L. Rathjens, D. and Safonov, A. Akchurin, N. Damgov, J. De Guio, F. Hegde, V and Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. and Peltola, T. Undleeb, S. Volobouev, I Whitbeck, A. and Greene, S. Gurrola, A. Janjam, R. Johns, W. Maguire, C. and Melo, A. Ni, H. Padeken, K. Romeo, F. Sheldon, P. and Tuo, S. Velkovska, J. Verweij, M. Arenton, M. W. and Barria, P. Cox, B. Cummings, G. Hakala, J. Hirosky, R. and Joyce, M. Ledovskoy, A. Neu, C. Tannenwald, B. and Wolfe, E. Xia, F. Harr, R. Karchin, P. E. Poudyal, N. and Sturdy, J. Thapa, P. Bose, T. Buchanan, J. Caillol, C. Carlsmith, D. Dasu, S. De Bruyn, I Dodd, L. and Galloni, C. He, H. Herndon, M. Herve, A. Hussain, U. and Klabbers, P. Lanaro, A. Loeliger, A. Long, K. Loveless, R. Sreekala, J. Madhusudanan Pinna, D. Ruggles, T. and Savin, A. Smith, W. H. Teague, D. Trembathreichert, S. and Woods, N. CMS Collaboration
Subjects: Nuclear Experiment
Abstract: Anisotropies in the initial energy density distribution of the quark-gluon plasma created in high energy heavy ion collisions lead to anisotropies in the azimuthal distributions of the final-state particles known as collective anisotropic flow. Fourier harmonic decomposition is used to quantify these anisotropies. The higher-order harmonics can be induced by the same order anisotropies (linear response) or by the combined influence of several lower order anisotropies (nonlinear response) in the initial state. The mixed highe-rorder anisotropic flow and nonlinear response coefficients of charged particles are measured as functions of transverse momentum and centrality in PbPb collisions at nucleon-nucleon center-of-mass energies root s(NN) = 2.76 and 5.02 TeV with the CMS detector. The results are compared with viscous hydrodynamic calculations using several different initial conditions, aswell asmicroscopic transport model calculations. None of the models provides a simultaneous description of the mixed higher-order flow harmonics and nonlinear response coefficients.
Published: 2020

13. Measurement of the t(t)over-barb(b)over-bar production cross section in the all-jet final state in pp collisions at root s=13 TeV

Author: Sirunyan, A. M. Tumasyan, A. Adam, W. Ambrogi, F. and Bergauer, T. Brandstetter, J. Dragicevic, M. Eroe, J. and Del Valle, A. Escalante Flechl, M. Fruehwirth, R. Jeitler, M. Krammer, N. Kraetschmer, I Liko, D. Madlener, T. and Mikulec, I Rad, N. Schieck, J. Schoefbeck, R. Spanring, M. Spitzbart, D. Waltenberger, W. Wulz, C-E Zarucki, M. and Drugakov, V Mossolov, V Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Di Croce, D. Janssen, X. Lelek, A. and Pieters, M. Sfar, H. Rejeb Van Haevermaet, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. Chhibra, S. S. De Clercq, J. D'Hondt, J. Lontkovskyi, D. Lowette, S. Marchesini, I Moortgat, S. Python, Q. and Skovpen, K. Tavernier, S. Van Doninck, W. Van Mulders, P. and Beghin, D. Bilin, B. Brun, H. Clerbaux, B. De Lentdecker, G. Delannoy, H. Dorney, B. Favart, L. and Grebenyuk, A. Kalsi, A. K. Popov, A. Postiau, N. and Starling, E. Thomas, L. Vander Velde, C. Vanlaer, P. and Vannerom, D. Cornelis, T. Dobur, D. Khvastunov, I and Niedziela, M. Roskas, C. Trocino, D. Tytgat, M. Verbeke, W. Vermassen, B. Vit, M. Zaganidis, N. Bondu, O. and Bruno, G. Caputo, C. David, P. Delaere, C. Delcourt, M. and Giammanco, A. Lemaitre, V Magitteri, A. Prisciandaro, J. and Saggio, A. Marono, M. Vidal Vischia, P. Zobec, J. and Alves, F. L. Alves, G. A. Correia Silva, G. Hensel, C. and Moraes, A. Rebello Teles, P. Belchior Batista Das Chagas, E. and Carvalho, W. Chinellato, J. Da Coelho, E. Da Costa, E. M. and Silveira, G. G. De Jesus Damiao, D. De Oliveira Martins, C. and Fonseca De Souza, S. Huertas Guativa, L. M. Malbouisson, H. and Martins, J. Matos Figueiredo, D. Medina Jaime, M. Melo De Almeida, M. Mora Herrera, C. Mundim, L. Nogima, H. and Prado Da Silva, W. L. Sanchez Rosas, L. J. Santoro, A. and Sznajder, A. Thiel, M. Tonelli Manganote, E. J. Torres Da Silva De Araujo, F. Vilela Pereira, A. Bernardes, C. A. and Calligaris, L. Fernandez Perez Tomei, T. R. Gregores, E. M. and Lemos, D. S. Mercadante, P. G. Novaes, S. F. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. and Bonchev, M. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. and Petkov, P. Fang, W. Gao, X. Yuan, L. Ahmad, M. and Chen, G. M. Chen, H. S. Chen, M. Jiang, C. H. Leggat, D. and Liao, H. Liu, Z. Shaheen, S. M. Spiezia, A. Tao, J. and Yazgan, E. Zhang, H. Zhang, S. Zhao, J. Agapitos, A. and Ban, Y. Chen, G. Levin, A. Li, J. Li, L. Li, Q. and Qian, S. J. Wang, D. Wang, Q. Hu, Z. Wang, Y. and Xiao, M. Avila, C. Cabrera, A. Florez, C. Gonzalez Hernandez, C. F. Segura Delgado, M. A. Mejia Guisao, J. Ruiz Alvarez, J. D. Salazar Gonzalez, C. A. Vanegas Arbelaez, N. and Godinovic, N. Lelas, D. Puljak, I Sculac, T. Antunovic, Z. Kovac, M. Brigljevic, V Ceci, S. Ferencek, D. and Kadija, K. Mesic, B. Roguljic, M. Starodumov, A. Susa, T. Ather, M. W. Attikis, A. Erodotou, E. Ioannou, A. and Kolosova, M. Konstantinou, S. Mavromanolakis, G. 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Mueller, R. Overton, D. and Pernie, L. Rathjens, D. Safonov, A. Akchurin, N. and Damgov, J. De Guio, F. Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. Peltola, T. Undleeb, S. Volobouev, I and Whitbeck, A. Greene, S. Gurrola, A. Janjam, R. and Johns, W. Maguire, C. Melo, A. Ni, H. Padeken, K. and Romeo, F. Sheldon, P. Tuo, S. Velkovska, J. Verweij, M. and Arenton, M. W. Barria, P. Cox, B. Cummings, G. and Hirosky, R. Joyce, M. Ledovskoy, A. Neu, C. Tannenwald, B. Wolfe, E. Xia, F. Harr, R. Karchin, P. E. and Poudyal, N. Sturdy, J. Thapa, P. Bose, T. Buchanan, J. and Caillol, C. Carlsmith, D. Dasu, S. De Bruyn, I Dodd, L. Fiori, F. Galloni, C. Gomber, B. He, H. Herndon, M. Herve, A. Hussain, U. Klabbers, P. Lanaro, A. and Loeliger, A. Long, K. Loveless, R. Sreekala, J. Madhusudanan and Ruggles, T. Savin, A. Smith, W. H. Teague, D. and Trembath-reichert, S. Woods, N. CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: A measurement of the production cross section of top quark pairs in association with two b jets (t (t) over barb (b) over bar) is presented using data collected in proton-proton collisions at root s=13 TeV by the CMS detector at the LHC corresponding to an integrated luminosity of 35.9 fb(-1). The cross section is measured in the all-jet decay channel of the top quark pair by selecting events containing at least eight jets, of which at least two are identified as originating from the hadronization of b quarks. A combination of multivariate analysis techniques is used to reduce the large background from multijet events not containing a top quark pair, and to help discriminate between jets originating from top quark decays and other additional jets. The cross section is determined for the total phase space to be 5.5 +/- 0.3 (stat)(-1.3)(+)(1.6) (syst)pb and also measured for two fiducial t (t) over barb (b) over bar, definitions. The measured cross sections are found to be larger than theoretical predictions by a factor of 1.5-2.4, corresponding to 1-2 standard deviations. (C) 2020 The Author. Published by Elsevier B.V.
Published: 2020

14. Running of the top quark mass from proton-proton collisions at root s=13 TeV

Author: Sirunyan, A. M. Tumasyan, A. Adam, W. Ambrogi, F. and Bergauer, T. Brandstetter, J. Dragicevic, M. Eroe, J. and Del Valle, A. Escalante Flechl, M. Fruehwirth, R. Jeitler, M. Krammer, N. Kraetschmer, I Liko, D. Madlener, T. and Mikulec, I Rad, N. Schieck, J. Schoefbeck, R. Spanring, M. Spitzbart, D. Waltenberger, W. Wulz, C-E Zarucki, M. and Drugakov, V Mossolov, V Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Di Croce, D. Janssen, X. Lelek, A. and Pieters, M. Sfar, H. Rejeb Van Haevermaet, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. Chhibra, S. S. De Clercq, J. Lontkovskyi, D. Lowette, S. Marchesini, I Moortgat, S. Python, Q. Skovpen, K. and Tavernier, S. Van Doninck, W. Van Mulders, P. Beghin, D. and Bilin, B. Brun, H. Clerbaux, B. De Lentdecker, G. and Delannoy, H. Dorney, B. Favart, L. Grebenyuk, A. Kalsi, A. K. Popov, A. Postiau, N. Starling, E. Thomas, L. and Vander Velde, C. Vanlaer, P. Vannerom, D. Cornelis, T. and Dobur, D. Khvastunov, I Niedziela, M. Roskas, C. Tytgat, M. Verbeke, W. Vermassen, B. Vit, M. Bondu, O. and Bruno, G. Caputo, C. David, P. Delaere, C. Delcourt, M. and Giammanco, A. Lemaitre, V Prisciandaro, J. Saggio, A. and Marono, M. Vidal Vischia, P. Zobec, J. Alves, F. L. and Alves, G. A. Correia Silva, G. Hensel, C. Moraes, A. and Rebello Teles, P. Belchior Batista Das Chagas, E. Carvalho, W. and Chinellato, J. Coelho, E. Da Costa, E. M. Da Silveira, G. G. De Jesus Damiao, D. De Oliveira Martins, C. Fonseca De Souza, S. Huertas Guativa, L. M. Malbouisson, H. Martins, J. and Matos Figueiredo, D. Medina Jaime, M. Melo De Almeida, M. and Herrera, C. Mora Mundim, L. Nogima, H. Prado Da Silva, W. L. Sanchez Rosas, L. J. Santoro, A. Sznajder, A. and Thiel, M. Tonelli Manganote, E. J. Torres Da Silva De Araujo, F. and Vilela Pereira, A. Bernardes, C. A. Calligaris, L. and Fernandez Perez Tomei, T. R. Gregores, E. M. Lemos, D. S. and Mercadante, P. G. Novaes, S. F. 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Olmedo Paneva, I, M. Si, W. Wang, L. and Wimpenny, S. Yates, B. R. Zhang, Y. Branson, J. G. and Cittolin, S. Cooperstein, S. Deelen, N. Derdzinski, M. and Gerosa, R. Gilbert, D. Hashemi, B. Klein, D. Krutelyov, V Letts, J. Masciovecchio, M. Padhi, S. Pieri, M. and Sharma, V Tadel, M. Wurthwein, F. Yagil, A. Della Porta, G. Zevi Amin, N. Bhandari, R. Campagnari, C. Citron, M. and Dutta, V Sevilla, M. Franco Incandela, J. Marsh, B. and Mei, H. Ovcharova, A. Qu, H. Richman, J. Sarica, U. and Stuart, D. Wang, S. Anderson, D. Bornheim, A. Cerri, O. and Dutta, I Lawhorn, J. M. Lu, N. Newman, H. B. Nguyen, T. Q. Pata, J. Spiropulu, M. Vlimant, J. R. Xie, S. and Zhang, Z. Zhu, R. Y. Andrews, M. B. Ferguson, T. and Mudholkar, T. Paulini, M. Sun, M. Vorobiev, I Weinberg, M. Cumalat, J. P. Ford, W. T. MacDonald, E. Mulholland, T. Patel, R. Perloff, A. Stenson, K. Ulmer, K. A. and Wagner, S. R. Alexander, J. Cheng, Y. Chu, J. Datta, A. and Frankenthal, A. Mcdermott, K. Patterson, J. R. Quach, D. and Ryd, A. Tan, S. M. Tao, Z. Thom, J. Wittich, P. and Zientek, M. Abdullin, S. Albrow, M. Alyari, M. and Apollinari, G. Apresyan, A. Apyan, A. Bauerdick, L. A. T. and Beretvas, A. Berry, D. Berryhill, J. Bhat, P. C. and Burkett, K. Butler, J. N. Canepa, A. Cerati, G. B. and Cheung, H. W. K. Chlebana, F. Cremonesi, M. Duarte, J. and Elvira, V. D. Freeman, J. Gecse, Z. Gottschalk, E. Gray, L. Green, D. Grunendahl, S. Gutsche, O. ReinsvoldHall, Allison Hanlon, J. Harris, R. M. Hasegawa, S. Heller, R. and Hirschauer, J. Jayatilaka, B. Jindariani, S. Johnson, M. and Joshi, U. Klijnsma, T. Klima, B. Kortelainen, M. J. and Kreis, B. Lammel, S. Lewis, J. Lincoln, D. Lipton, R. and Liu, M. Liu, T. Lykken, J. Maeshima, K. Marraffino, J. M. Mason, D. McBride, P. Merkel, P. Mrenna, S. and Nahn, S. Papadimitriou, V Pedro, K. Pena, C. Rakness, G. and Ravera, F. Ristori, L. Schneider, B. Sexton-Kennedy, E. and Smith, N. Soha, A. Spalding, W. J. Spiegel, L. and Stoynev, S. Strait, J. Strobbe, N. Taylor, L. Tkaczyk, S. Tran, V, N. Uplegger, L. Vaandering, E. W. Vernieri, C. Vidal, R. Wang, M. Weber, H. A. Acosta, D. Avery, P. Bourilkov, D. Brinkerhoff, A. Cadamuro, L. Carnes, A. and Cherepanov, V Errico, F. Field, R. D. Gleyzer, V, S. and Guerrero, D. Joshi, B. M. Kim, M. Konigsberg, J. and Korytov, A. H Lo, K. Ma, P. Matchev, K. Menendez, N. and Mitselmakher, G. Rosenzweig, D. Shi, K. Wang, J. Zuo, X. and Joshi, Y. R. Adams, T. Askew, A. Hagopian, S. and Hagopian, V Johnson, K. F. Khurana, R. Kolberg, T. and Martinez, G. Perry, T. Prosper, H. Schiber, C. Yohay, R. and Zhang, J. Baarmand, M. M. Hohlmann, M. Noonan, D. and Rahmani, M. Saunders, M. Yumiceva, F. Adams, M. R. and Apanasevich, L. Betts, R. R. Cavanaugh, R. Chen, X. and Dittmer, S. Evdokimov, O. Gerber, C. E. Hangal, D. A. and Hofman, D. J. Jung, K. Mills, C. Roy, T. Tonjes, M. B. and Varelas, N. Viinikainen, J. Wang, H. Wang, X. Wu, Z. and Alhusseini, M. Bilki, B. Clarida, W. Dilsiz, K. and Durgut, S. Gandrajula, R. P. Haytmyradov, M. Khristenko, V and Koseyan, O. K. Merlo, J-P Mestvirishvili, A. Moeller, A. and Nachtman, J. Ogul, H. Onel, Y. Ozok, F. Penzo, A. and Snyder, C. Tiras, E. Wetzel, J. Blumenfeld, B. and Cocoros, A. Eminizer, N. Gritsan, V, A. Hung, W. T. and Kyriacou, S. Maksimovic, P. Roskes, J. Swartz, M. and Barrera, C. Baldenegro Baringer, P. Bean, A. Boren, S. and Bowen, J. Bylinkin, A. Isidori, T. Khalil, S. King, J. and Krintiras, G. Kropivnitskaya, A. Lindsey, C. Majumder, D. Mcbrayer, W. Minafra, N. Murray, M. Rogan, C. and Royon, C. Sanders, S. Schmitz, E. Takaki, J. D. Tapia and Williams, J. Wilson, G. Duric, S. Ivanov, A. Kaadze, K. and Kim, D. Maravin, Y. Mendis, D. R. Mitchell, T. and Modak, A. Mohammadi, A. Rebassoo, F. Wright, D. Baden, A. Baron, O. Belloni, A. Eno, S. C. Feng, Y. Hadley, N. J. Jabeen, S. Jeng, G. Y. Kellogg, R. G. Kunkle, J. and Mignerey, A. C. Nabili, S. Ricci-Tam, F. Shin, Y. H. and Skuja, A. Tonwar, S. C. Wong, K. Abercrombie, D. Allen, B. Baty, A. Bi, R. Brandt, S. Busza, W. Cali, I. A. and Ceballos, G. Gomez Goncharov, M. Harris, P. Hsu, D. and Hu, M. Klute, M. Kovalskyi, D. Lee, Y-J Luckey, P. D. and Maier, B. Marini, A. C. Mcginn, C. Mironov, C. and Narayanan, S. Niu, X. Paus, C. Rankin, D. Roland, C. and Roland, G. Shi, Z. Stephans, G. S. F. Sumorok, K. Tatar, K. Velicanu, D. Wang, T. W. Wyslouch, B. Chatterjee, R. M. Evans, A. Guts, S. Hansen, P. Hiltbrand, J. Jain, Sh Kubota, Y. Lesko, Z. Mans, J. Revering, M. and Rusack, R. Saradhy, R. Schroeder, N. Wadud, M. A. and Acosta, J. G. Oliveros, S. Bloom, K. Claes, D. R. and Fangmeier, C. Finco, L. Golf, F. Kamalieddin, R. and Kravchenko, I Siado, J. E. Snow, G. R. Stieger, B. Tabb, W. Agarwal, G. Harrington, C. Iashvili, I. Kharchilava, A. McLean, C. Nguyen, D. Parker, A. Pekkanen, J. and Rappoccio, S. Roozbahani, B. Alverson, G. Barberis, E. and Freer, C. Haddad, Y. Hortiangtham, A. Madigan, G. and Marzocchi, B. Morse, D. M. Orimoto, T. Skinnari, L. and Tishelman-Charny, A. Wamorkar, T. Wang, B. Wisecarver, A. and Wood, D. Bueghly, J. Gunter, T. Hahn, K. A. Odell, N. Schmitt, M. H. Sung, K. Trovato, M. Velasco, M. and Bucci, R. Dev, N. Goldouzian, R. Hildreth, M. Anampa, K. Hurtado Jessop, C. Karmgard, D. J. Lannon, K. Li, W. and Loukas, N. Marinelli, N. Mcalister, I Meng, F. Mueller, C. Musienko, Y. Planer, M. Ruchti, R. Siddireddy, P. and Smith, G. Taroni, S. Wayne, M. Wightman, A. Wolf, M. and Woodard, A. Alimena, J. Bylsma, B. Durkin, L. S. and Francis, B. Hill, C. Ji, W. Lefeld, A. Ling, T. Y. and Winer, B. L. Dezoort, G. Elmer, P. Hardenbrook, J. and Haubrich, N. Higginbotham, S. Kalogeropoulos, A. Kwan, S. and Lange, D. Lucchini, M. T. Luo, J. Marlow, D. Mei, K. and Ojalvo, I Olsen, J. Palmer, C. Piroue, P. Stickland, D. Tully, C. Norberg, S. Barker, A. Barnes, V. E. and Gutay, L. Jones, M. Jung, A. W. Khatiwada, A. Mahakud, B. Miller, D. H. Negro, G. Neumeister, N. Peng, C. C. and Piperov, S. Qiu, H. Schulte, J. F. Trevisani, N. and Wang, F. Xiao, R. Xie, W. Cheng, T. Dolen, J. and Parashar, N. Behrens, U. Ecklund, K. M. Freed, S. and Geurts, F. J. M. Kilpatrick, M. Kumar, Arun Padley, B. P. and Redjimi, R. Roberts, J. Rorie, J. Shi, W. Leiton, A. G. Stahl Tu, Z. Zhang, A. Bodek, A. de Barbaro, P. and Demina, R. Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. Garcia-Bellido, A. Hindrichs, O. Khukhunaishvili, A. and Ranken, E. Taus, R. Chiarito, B. Chou, J. P. Gandrakota, A. Gershtein, Y. Halkiadakis, E. Hart, A. Heindl, M. and Hughes, E. Kaplan, S. Laflotte, I Lath, A. Montalvo, R. and Nash, K. Osherson, M. Saka, H. Salur, S. Schnetzer, S. Somalwar, S. Stone, R. Thomas, S. Acharya, H. and Delannoy, A. G. Spanier, S. Bouhali, O. Dalchenko, M. De Mattia, M. Delgado, A. Dildick, S. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Luo, S. Malhotra, S. Marley, D. Mueller, R. Overton, D. Pernie, L. Rathjens, D. and Safonov, A. Akchurin, N. Damgov, J. De Guio, F. Hegde, V and Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. and Peltola, T. Undleeb, S. Volobouev, I Whitbeck, A. and Greene, S. Gurrola, A. Janjam, R. Johns, W. Maguire, C. and Melo, A. Ni, H. Padeken, K. Romeo, F. Sheldon, P. and Tuo, S. Velkovska, J. Verweij, M. Arenton, M. W. and Barria, P. Cox, B. Cummings, G. Hakala, J. Hirosky, R. and Joyce, M. Ledovskoy, A. Neu, C. Tannenwald, B. and Wolfe, E. Xia, F. Harr, R. Karchin, P. E. Poudyal, N. and Sturdy, J. Thapa, P. Bose, T. Buchanan, J. Caillol, C. Carlsmith, D. Dasu, S. De Bruyn, I Dodd, L. and Galloni, C. He, H. Herndon, M. Herve, A. Hussain, U. and Klabbers, P. Lanaro, A. Loeliger, A. Long, K. Loveless, R. Sreekala, J. Madhusudanan Pinna, D. Ruggles, T. and Savin, A. Smith, W. H. Teague, D. Trembathreichert, S. and Woods, N. CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: The running of the top quark mass is experimentally investigated for the first time. The mass of the top quark in the modified minimal subtraction ((MS) over bar) renormalization scheme is extracted from a comparison of the differential top quark-antiquark (t (t) over bar) cross section as a function of the invariant mass of the t (t) over bar system to next-to-leading-order theoretical predictions. The differential cross section is determined at the parton level by means of a maximum-likelihood fit to distributions of final-state observables. The analysis is performed using t (t) over bar candidate events in the e(+/-)mu(-/+) channel in proton-proton collision data at a centre-of-mass energy of 13 TeV recorded by the CMS detector at the CERN LHC in 2016, corresponding to an integrated luminosity of 35.9 fb(-1). The extracted running is found to be compatible with the scale dependence predicted by the corresponding renormalization group equation. In this analysis, the running is probed up to a scale of the order of 1 TeV. (C) 2020 The Author(s). Published by Elsevier B.V.
Published: 2020

15. 303 No difference in skin cancer rates by transplanted organ type after the initial skin cancer

Author: L.D. Edwards, Allison Hanlon, Mary-Margaret Chren, and Lee Wheless
Subjects: Pathology, medicine.medical_specialty, business.industry, medicine, Cell Biology, Dermatology, Skin cancer, medicine.disease, business, Molecular Biology, Biochemistry
Published: 2021

16. LN2, CD10, and Ezrin Do Not Distinguish Between Atypical Fibroxanthoma and Undifferentiated Pleomorphic Sarcoma or Predict Clinical Outcome

Author: Thomas Stasko, Allison Hanlon, Nika Cyrus, Anjela Galan, and Dan Christiansen
Subjects: Adult, Male, Pathology, medicine.medical_specialty, Skin Neoplasms, medicine.medical_treatment, Histiocytoma, Malignant Fibrous, Dermatology, Sensitivity and Specificity, Undifferentiated Pleomorphic Sarcoma, Diagnosis, Differential, Hospitals, University, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Ezrin, Predictive Value of Tests, Biomarkers, Tumor, Mohs surgery, Humans, Medicine, Neoplasm, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Poorly differentiated, Histocompatibility Antigens Class II, Follow up studies, Atypical fibroxanthoma, Sarcoma, General Medicine, Middle Aged, Mohs Surgery, medicine.disease, Survival Analysis, United States, Antigens, Differentiation, B-Lymphocyte, Cytoskeletal Proteins, Treatment Outcome, Multicenter study, 030220 oncology & carcinogenesis, Female, Neprilysin, Surgery, business, Follow-Up Studies
Abstract: Atypical fibroxanthoma (AFX) is a rare cutaneous spindled cell neoplasm. For both diagnostic and therapeutic purposes, it is important to distinguish AFX from other poorly differentiated tumors, including undifferentiated pleomorphic sarcoma (UPS).The authors aimed to identify the clinical, histologic, and immunohistochemical expression of LN2, ezrin, and CD10 in AFX and UPS tumors.The authors retrospectively examined the charts of patients with AFX and UPS treated with Mohs micrographic surgery (MMS) at 2 academic institutions. Patient demographics, tumor characteristics, and clinical course data were collected. Immunohistochemical stains were performed on primary and recurrent AFX and UPS tumors with monoclonal antibodies against the B-cell marker LN2 (CD74), CD10, and ezrin.In the series of 169 patients with AFX included in this study, local recurrence was rare at 3%. In contrast, the seven patients with UPS had an aggressive clinical course with 1 local recurrence and 2 distant metastases. Immunohistochemistry staining for ezrin, LN2, and CD10 were similar in AFX and UPS tumors.AFX can be treated with MMS with rare instances of recurrence. Undifferentiated pleomorphic sarcoma has a more aggressive clinical course with increased risk for recurrence and metastasis. Staining with ezrin, LN2, and CD10 did not differentiate AFX or UPS tumors.
Published: 2017

17. Merkel Cell Carcinoma

Author: Allison Hanlon
Subjects: business.industry, Merkel cell carcinoma, medicine, Cancer research, Dermatology, Skin cancer, medicine.disease, business
Published: 2019

18. Search for long-lived particles using nonprompt jets and missing transverse momentum with proton-proton collisions at root s=13 TeV

Author: Sirunyan, A. M. Tumasyan, A. Adam, W. Ambrogi, F. and Bergauer, T. Brandstetter, J. Dragicevic, M. Eroe, J. and Del Valle, A. Escalante Flechl, M. Fruehwirth, R. Jeitler, M. Krammer, N. Kraetschmer, I Liko, D. Madlener, T. and Mikulec, I Rad, N. Schieck, J. Schoefbeck, R. Spanring, M. Spitzbart, D. Waltenberger, W. Wulz, C-E Zarucki, M. and Drugakov, V Mossolov, V Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Di Croce, D. Janssen, X. Lelek, A. and Pieters, M. Sfar, H. Rejeb Van Haevermaet, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. Chhibra, S. S. D'Hondt, J. De Clercq, J. Lontkovskyi, D. Lowette, S. Marchesini, I Moortgat, S. Moreels, L. and Python, Q. Skovpen, K. Tavernier, S. Van Doninck, W. and Van Mulders, P. Van Parijs, I Beghin, D. Bilin, B. Brun, H. Clerbaux, B. De Lentdecker, G. Delannoy, H. Dorney, B. Favart, L. Grebenyuk, A. Kalsi, A. K. Popov, A. and Postiau, N. Starling, E. Thomas, L. Vander Velde, C. and Vanlaer, P. Vannerom, D. 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Dildick, S. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Luo, S. Marley, D. Mueller, R. Overton, D. Pernie, L. Rathjens, D. Safonov, A. and Akchurin, N. Damgov, J. De Guio, F. Kunori, S. and Lamichhane, K. Mengke, T. Muthumuni, S. Peltola, T. and Undleeb, S. Volobouev, I Whitbeck, A. Greene, S. and Gurrola, A. Janjam, R. Johns, W. Maguire, C. Melo, A. and Ni, H. Padeken, K. Romeo, F. Sheldon, P. Tuo, S. and Velkovska, J. Verweij, M. Arenton, M. W. Barria, P. Cox, B. Cummings, G. Hirosky, R. Joyce, M. Ledovskoy, A. and Neu, C. Tannenwald, B. Wolfe, E. Xia, F. Harr, R. and Karchin, P. E. Poudyal, N. Sturdy, J. Thapa, P. Zaleski, S. Buchanan, J. Caillol, C. Carlsmith, D. Dasu, S. and De Bruyn, I Dodd, L. Fiori, F. Galloni, C. Gomber, B. and He, H. Herndon, M. Herve, A. Hussain, U. Klabbers, P. Lanaro, A. Loeliger, A. Long, K. Loveless, R. and Sreekala, J. Madhusudanan Ruggles, T. Savin, A. Smith, W. H. and Teague, D. Trembath-reichert, S. Woods, N. CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: A search for long-lived particles decaying to displaced, nonprompt jets and missing transverse momentum is presented. The data sample corresponds to an integrated luminosity of 137 fb(-1) of proton-proton collisions at a center-of-mass energy of 13 TeV collected by the CMS experiment at the CERN LHC in 2016-2018. Candidate signal events containing nonprompt jets are identified using the timing capabilities of the CMS electromagnetic calorimeter. The results of the search are consistent with the background prediction and are interpreted using a gauge-mediated supersymmetry breaking reference model with a gluino next-to-lightest supersymmetric particle. In this model, gluino masses up to 2100, 2500, and 1900 GeV are excluded at 95% confidence level for proper decay lengths of 0.3, 1, and 100 m, respectively. These are the best limits to date for such massive gluinos with proper decay lengths greater than similar to 0.5 m. (C) 2019 The Author. Published by Elsevier B.V.
Published: 2019

19. Evidence for light-by-light scattering and searches for axion-like particles in ultraperipheral PbPb collisions at root s(NN)=5.02 TeV

Author: Sirunyan, A. M. Tumasyan, A. Adam, W. Ambrogi, F. and Bergauer, T. Brandstetter, J. Dragicevic, M. Eroe, J. and Del Valle, A. Escalante Flechl, M. Fruehwirth, R. Jeitler, M. Krammer, N. Kraetschmer, I Liko, D. Madlener, T. and Mikulec, I Rad, N. Schieck, J. Schoefbeck, R. Spanring, M. Spitzbart, D. Waltenberger, W. Wulz, C-E Zarucki, M. and Drugakov, V Mossolov, V Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Di Croce, D. Janssen, X. Lauwers, J. and Lelek, A. Pieters, M. Sfar, H. Rejeb Van Haevermaet, H. and Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. Chhibra, S. S. D'Hondt, J. De Clercq, J. and Lontkovskyi, D. Lowette, S. Marchesini, I Moortgat, S. and Moreels, L. Python, Q. Skovpen, K. Tavernier, S. Van Doninck, W. Van Mulders, P. Van Parijs, I Beghin, D. and Bilin, B. Brun, H. Clerbaux, B. De Lentdecker, G. and Delannoy, H. Dorney, B. Favart, L. Grebenyuk, A. Kalsi, A. K. Luetic, J. Popov, A. Postiau, N. Starling, E. and Thomas, L. 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Stoynev, S. Strait, J. and Strobbe, N. Taylor, L. Tkaczyk, S. Tran, V, N. Uplegger, L. Vaandering, E. W. Vernieri, C. Verzocchi, M. Vidal, R. Wang, M. Weber, H. A. Acosta, D. Avery, P. and Bortignon, P. Bourilkov, D. Brinkerhoff, A. Cadamuro, L. and Carnes, A. Cherepanov, V Curry, D. Errico, F. Field, R. D. Gleyzer, V, S. Joshi, B. M. Kim, M. Konigsberg, J. and Korytov, A. Lo, K. H. Ma, P. Matchev, K. Menendez, N. Mitselmakher, G. Rosenzweig, D. Shi, K. Wang, J. and Zuo, X. Joshi, Y. R. Adams, T. Askew, A. Hagopian, S. and Hagopian, V Johnson, K. F. Khurana, R. Kolberg, T. and Martinez, G. Perry, T. Prosper, H. Schiber, C. Yohay, R. and Zhang, J. Baarmand, M. M. Bhopatkar, V Hohlmann, M. and Noonan, D. Rahmani, M. Saunders, M. Yumiceva, F. Adams, M. R. Apanasevich, L. Berry, D. Betts, R. R. Cavanaugh, R. Chen, X. Dittmer, S. Evdokimov, O. Gerber, C. E. and Hangal, D. A. Hofman, D. J. Jung, K. Mills, C. Roy, T. and Tonjes, M. B. Varelas, N. Wang, H. Wang, X. Wu, Z. and Alhusseini, M. 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Seidel, M. Shin, Y. H. Skuja, A. Tonwar, S. C. Wong, K. Abercrombie, D. Allen, B. Baty, A. and Bi, R. Brandt, S. Busza, W. Cali, I. A. DAlfonso, M. and Ceballos, G. Gomez Goncharov, M. Harris, P. Hsu, D. Hu, M. Klute, M. Kovalskyi, D. Lee, Y-J Luckey, P. D. and Maier, B. Marini, A. C. Mcginn, C. Mironov, C. and Narayanan, S. Niu, X. Paus, C. Rankin, D. Roland, C. and Roland, G. Shi, Z. Stephans, G. S. F. Sumorok, K. Tatar, K. Velicanu, D. Wang, T. W. Wyslouch, B. Benvenuti, A. C. Chatterjee, R. M. Evans, A. Guts, S. Hansen, P. and Hiltbrand, J. Kalafut, S. Kubota, Y. Lesko, Z. Mans, J. and Rusack, R. Wadud, M. A. Acosta, J. G. Oliveros, S. and Bloom, K. Claes, D. R. Fangmeier, C. Finco, L. Golf, F. and Suarez, R. Gonzalez Kamalieddin, R. Kravchenko, I Siado, J. E. Snow, G. R. Stieger, B. Agarwal, G. Harrington, C. and Iashvili, I. Kharchilava, A. Mclean, C. Nguyen, D. and Parker, A. Pekkanen, J. Rappoccio, S. Roozbahani, B. and Alverson, G. Barberis, E. Freer, C. 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Delgado, A. Dildick, S. and Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Luo, S. and Marley, D. Mueller, R. Overton, D. Pernie, L. Rathjens, D. Safonov, A. Akchurin, N. Damgov, J. De Guio, F. and Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. and Peltola, T. Undleeb, S. Volobouev, I Whitbeck, A. and Greene, S. Gurrola, A. Janjam, R. Johns, W. Maguire, C. and Melo, A. Ni, H. Padeken, K. Romeo, F. Sheldon, P. and Tuo, S. Velkovska, J. Verweij, M. Arenton, M. W. and Barria, P. Cox, B. Cummings, G. Hirosky, R. Joyce, M. and Ledovskoy, A. Neu, C. Tannenwald, B. Wolfe, E. Xia, F. Harr, R. Karchin, P. E. Poudyal, N. Sturdy, J. and Thapa, P. Zaleski, S. Buchanan, J. Caillol, C. and Carlsmith, D. Dasu, S. De Bruyn, I Dodd, L. Fiori, F. and Galloni, C. Gomber, B. Herndon, M. Herve, A. and Hussain, U. Klabbers, P. Lanaro, A. Loeliger, A. Long, K. Loveless, R. Sreekala, J. Madhusudanan Ruggles, T. and Savin, A. Smith, W. H. Teague, D. Trembath-Reichert, S. and Woods, N. CMS Collaboration
Subjects: Astrophysics::High Energy Astrophysical Phenomena, High Energy Physics::Experiment, Nuclear Experiment
Abstract: Evidence for the light-by-light scattering process, gamma gamma -> gamma gamma, in ultraperipheral PbPb collisions at a centre-of-mass energy per nucleon pair of 5.02 TeV is reported. The analysis is conducted using a data sample corresponding to an integrated luminosity of 390 mu b(-1) recorded by the CMS experiment at the LHC. Light-by-light scattering processes are selected in events with two photons exclusively produced, each with transverse energy E-T(gamma) > 2 GeV, pseudorapidity vertical bar eta(gamma)vertical bar < 2.4, diphoton invariant mass m(gamma gamma) > 5 GeV, diphoton transverse momentum p(T)(gamma gamma) < 1 GeV, and diphoton acoplanarity below 0.01. After all selection criteria are applied, 14 events are observed, compared to expectations of 9.0 +/- 0.9 (theo) events for the signal and 4.0 +/- 1.2 (stat) for the background processes. The excess observed in data relative to the background-only expectation corresponds to a significance of 3.7 standard deviations, and has properties consistent with those expected for the light-by-light scattering signal. The measured fiducial light-by-light scattering cross section, sigma(fid)(gamma gamma -> gamma gamma) = 120 +/- 46(stat) +/- 28(syst) +/- 12(theo) nb, is consistent with the standard model prediction. The m(gamma gamma) distribution is used to set new exclusion limits on the production of pseudoscalar axion-like particles, via the gamma gamma -> a -> gamma gamma process, in the mass range m(a) = 5-90 GeV. (C) 2019 The Author(s). Published by Elsevier B.V.
Published: 2019

20. Search for Higgs and Z boson decays to J/psi or Y pairs in the four-muon final state in proton-proton collisions at root s=13 TeV

Author: Sirunyan, A. M. Tumasyan, A. Adam, W. Ambrogi, F. and Bergauer, T. Brandstetter, J. Dragicevic, M. Eroe, J. and Del Valle, A. Escalante Flechl, M. Fruehwirth, R. Jeitler, M. Krammer, N. Kraetschmer, I Liko, D. Madlener, T. and Mikulec, I Rad, N. Schieck, J. Schoefbeck, R. Spanring, M. Spitzbart, D. Waltenberger, W. Wulz, C-E Zarucki, M. and Drugakov, V Mossolov, V Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Di Croce, D. Janssen, X. Lauwers, J. and Lelek, A. Pieters, M. Sfar, H. Rejeb Van Haevermaet, H. and Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. Chhibra, S. S. D'Hondt, J. De Clercq, J. and Lontkovskyi, D. Lowette, S. Marchesini, I Moortgat, S. and Moreels, L. Python, Q. Skovpen, K. Tavernier, S. Van Doninck, W. Van Mulders, P. Van Parijs, I Beghin, D. and Bilin, B. Brun, H. Clerbaux, B. De Lentdecker, G. and Delannoy, H. Dorney, B. Favart, L. Grebenyuk, A. Kalsi, A. K. Luetic, J. Popov, A. Postiau, N. Starling, E. and Thomas, L. 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Backhaus, M. and Berger, P. Chernyavskaya, N. Dissertori, G. Dittmar, M. and Donega, M. Dorfer, C. Espinosa, T. A. Gomez Grab, C. and Hits, D. Klijnsma, T. Lustermann, W. Manzoni, R. A. and Marionneau, M. Meinhard, M. T. Micheli, F. Musella, P. and Nessi-Tedaldi, F. Pauss, F. Perrin, G. Perrozzi, L. and Pigazzini, S. Reichmann, M. Reissel, C. Reitenspiess, T. and Ruini, D. Becerra, D. A. Sanz Schonenberger, M. Shchutska, L. Olsson, M. L. Vesterbacka Wallny, R. Zhu, D. H. and Aarrestad, T. K. Amsler, C. Brzhechko, D. Canelli, M. F. and De Cosa, A. Del Burgo, R. Donato, S. Kilminster, B. and Leontsinis, S. Mikuni, V. M. Neutelings, I Rauco, G. and Robmann, P. Salerno, D. Schweiger, K. Seitz, C. and Takahashi, Y. Wertz, S. Zucchetta, A. Doan, T. H. Kuo, C. M. Lin, W. Roy, A. Yu, S. S. Chang, P. Chao, Y. and Chen, K. F. Chen, P. H. Hou, W-S Li, Y. Y. Lu, R-S and Paganis, E. Psallidas, A. Steen, A. Asavapibhop, B. and Asawatangtrakuldee, C. Srimanobhas, N. Suwonjandee, N. Bat, A. Boran, F. Cerci, S. Damarseckin, S. Demiroglu, Z. S. and Dolek, F. Dozen, C. Dumanoglu, I Gokbulut, G. and GurpinarGuler, Emine Guler, Y. Hos, I Isik, C. Kangal, E. E. Kara, O. Topaksu, A. Kayis Kiminsu, U. Oglakci, M. and Onengut, G. Ozdemir, K. Ozturk, S. Simsek, A. E. and Cerci, D. Sunar Tok, U. G. Turkcapar, S. Zorbakir, I. S. and Zorbilmez, C. Isildak, B. Karapinar, G. Yalvac, M. and Atakisi, I. O. Gulmez, E. Kaya, M. Kaya, O. Kaynak, B. and Ozcelik, O. Tekten, S. Yetkin, E. A. Cakir, A. and Komurcu, Y. Sen, S. Ozkorucuklu, S. Grynyov, B. Levchuk, L. Ball, F. Bhal, E. Bologna, S. Brooke, J. J. and Burns, D. Clement, E. Cussans, D. Flacher, H. Goldstein, J. Heath, G. P. Heath, H. F. Kreczko, L. Paramesvaran, S. Penning, B. Sakuma, T. El Nasr-Storey, S. Seif Smith, D. Smith, V. J. Taylor, J. Titterton, A. Bell, K. W. and Brew, C. Brown, R. M. Cieri, D. Cockerill, D. J. A. and Coughlan, J. A. Harder, K. Harper, S. Linacre, J. and Manolopoulos, K. Newbold, D. M. Olaiya, E. Petyt, D. and Reis, T. Schuh, T. Shepherd-Themistocleous, C. H. Thea, A. and Tomalin, I. R. Williams, T. Womersley, W. J. Bainbridge, R. Bloch, P. Borg, J. Breeze, S. Buchmuller, O. and Bundock, A. SinghChahal, Gurpreet Colling, D. Dauncey, P. and Davies, G. Della Negra, M. Di Maria, R. Everaerts, P. and Hall, G. Iles, G. James, T. Komm, M. Laner, C. and Lyons, L. Magnan, A-M Malik, S. Martelli, A. Milosevic, V Nash, J. Palladino, V Pesaresi, M. Raymond, D. M. and Richards, A. Rose, A. Scott, E. Seez, C. Shtipliyski, A. and Stoye, M. Strebler, T. Summers, S. Tapper, A. and Uchida, K. Virdee, T. Wardle, N. Winterbottom, D. and Wright, J. Zecchinelli, A. G. Zenz, S. C. Cole, J. E. and Hobson, P. R. Khan, A. Kyberd, P. Mackay, C. K. Morton, A. Reid, I. D. Teodorescu, L. Zahid, S. Call, K. and Dittmann, J. Hatakeyama, K. Madrid, C. McMaster, B. and Pastika, N. Smith, C. Bartek, R. Dominguez, A. Uniyal, R. Buccilli, A. Cooper, I, S. Henderson, C. Rumerio, P. and West, C. Arcaro, D. Bose, T. Demiragli, Z. Gastler, D. Girgis, S. Pinna, D. Richardson, C. Rohlf, J. and Sperka, D. Suarez, I Sulak, L. Zou, D. Benelli, G. and Burkle, B. Coubez, X. Cutts, D. Duh, Y. T. Hadley, M. and Hakala, J. Heintz, U. Hogan, J. M. Kwok, K. H. M. and Laird, E. Landsberg, G. Mao, Z. Narain, M. Sagir, S. and Syarif, R. Usai, E. Yu, D. Band, R. Brainerd, C. and Breedon, R. Sanchez, M. Calderon De La Barca Chertok, M. and Conway, J. Conway, R. Cox, P. T. Erbacher, R. Flores, C. and Funk, G. Jensen, F. Ko, W. Kukral, O. Lander, R. and Mulhearn, M. Pellett, D. Pilot, J. Shi, M. Stolp, D. and Taylor, D. Tos, K. Tripathi, M. Wang, Z. Zhang, F. and Bachtis, M. Bravo, C. Cousins, R. Dasgupta, A. Florent, A. Hauser, J. Ignatenko, M. Mccoll, N. Nash, W. A. and Regnard, S. Saltzberg, D. Schnaible, C. Stone, B. and Valuev, V. Burt, K. Clare, R. Gary, J. W. Shirazi, S. M. A. Ghiasi Hanson, G. Karapostoli, G. Kennedy, E. Long, O. R. Negrete, M. Olmedo Paneva, I, M. Si, W. Wang, L. and Wei, H. Wimpenny, S. Yates, B. R. Zhang, Y. Branson, J. G. Cittolin, S. Derdzinski, M. Gerosa, R. Gilbert, D. and Hashemi, B. Klein, D. Krutelyov, V Letts, J. and Masciovecchio, M. May, S. Padhi, S. Pieri, M. Sharma, V and Tadel, M. Wurthwein, F. Yagil, A. Della Porta, G. Zevi and Amin, N. Bhandari, R. Campagnari, C. Citron, M. and Dutta, V Sevilla, M. Franco Gouskos, L. Incandela, J. and Marsh, B. Mei, H. Ovcharova, A. Qu, H. Richman, J. and Sarica, U. Stuart, D. Wang, S. Yoo, J. Anderson, D. and Bornheim, A. Cerri, O. Dutta, I Lawhorn, J. M. Lu, N. and Mao, J. Newman, H. B. Nguyen, T. Q. Pata, J. and Spiropulu, M. Vlimant, J. R. Xie, S. Zhang, Z. Zhu, R. Y. Andrews, M. B. Ferguson, T. Mudholkar, T. Paulini, M. and Sun, M. Vorobiev, I Weinberg, M. Cumalat, J. P. and Ford, W. T. Johnson, A. MacDonald, E. Mulholland, T. and Patel, R. Perloff, A. Stenson, K. Ulmer, K. A. Wagner, S. R. Alexander, J. Chaves, J. Cheng, Y. Chu, J. and Datta, A. Frankenthal, A. Mcdermott, K. Mirman, N. and Patterson, J. R. Quach, D. Rinkevicius, A. Ryd, A. Tan, S. M. Tao, Z. Thom, J. Wittich, P. Zientek, M. and Abdullin, S. Albrow, M. Alyari, M. Apollinari, G. and Apresyan, A. Apyan, A. Bauerdick, L. A. T. Beretvas, A. and Berryhill, J. Bhat, P. C. Burkett, K. Butler, J. N. and Canepa, A. Cerati, G. B. Cheung, H. W. K. Chlebana, F. and Cremonesi, M. Duarte, J. Elvira, V. D. Freeman, J. and Gecse, Z. Gottschalk, E. Gray, L. Green, D. Grnendahl, S. Gutsche, O. ReinsvoldHall, Allison Hanlon, J. Harris, R. M. Hasegawa, S. Heller, R. Hirschauer, J. Jayatilaka, B. Jindariani, S. Johnson, M. Joshi, U. Klima, B. and Kortelainen, M. J. Kreis, B. Lammel, S. Lewis, J. and Lincoln, D. Lipton, R. Liu, M. Liu, T. Lykken, J. and Maeshima, K. Marraffino, J. M. Mason, D. McBride, P. and Merkel, P. Mrenna, S. Nahn, S. O'Dell, V Papadimitriou, V Pedro, K. Pena, C. Rakness, G. Ravera, F. Ristori, L. Schneider, B. Sexton-Kennedy, E. Smith, N. Soha, A. and Spalding, W. J. Spiegel, L. Stoynev, S. Strait, J. and Strobbe, N. Taylor, L. Tkaczyk, S. Tran, V, N. Uplegger, L. Vaandering, E. W. Vernieri, C. Verzocchi, M. Vidal, R. Wang, M. Weber, H. A. Acosta, D. Avery, P. and Bortignon, P. Bourilkov, D. Brinkerhoff, A. Cadamuro, L. and Carnes, A. Cherepanov, V Curry, D. Errico, F. Field, R. D. Gleyzer, V, S. Joshi, B. M. Kim, M. Konigsberg, J. and Korytov, A. Lo, K. H. Ma, P. Matchev, K. Menendez, N. Mitselmakher, G. Rosenzweig, D. Shi, K. Wang, J. and Zuo, X. Joshi, Y. R. Adams, T. Askew, A. Hagopian, S. and Hagopian, V Johnson, K. F. Khurana, R. Kolberg, T. and Martinez, G. Perry, T. Prosper, H. Schiber, C. Yohay, R. and Zhang, J. Baarmand, M. M. Bhopatkar, V Hohlmann, M. and Noonan, D. Rahmani, M. Saunders, M. Yumiceva, F. Adams, M. R. Apanasevich, L. Berry, D. Betts, R. R. Cavanaugh, R. Chen, X. Dittmer, S. Evdokimov, O. Gerber, C. E. and Hangal, D. A. Hofman, D. J. Jung, K. Mills, C. Roy, T. and Tonjes, M. B. Varelas, N. Wang, H. Wang, X. Wu, Z. and Alhusseini, M. Bilki, B. Clarida, W. Dilsiz, K. and Durgut, S. Gandrajula, R. P. Haytmyradov, M. Khristenko, V and Koseyan, O. K. Merlo, J-P Mestvirishvili, A. Moeller, A. and Nachtman, J. Ogul, H. Onel, Y. Ozok, F. Penzo, A. and Snyder, C. Tiras, E. Wetzel, J. Blumenfeld, B. and Cocoros, A. Eminizer, N. Fehling, D. Feng, L. Gritsan, V, A. Hung, W. T. Maksimovic, P. Roskes, J. Swartz, M. and Xiao, M. Barrera, C. Baldenegro Baringer, P. Bean, A. and Boren, S. Bowen, J. Bylinkin, A. Isidori, T. Khalil, S. King, J. Krintiras, G. Kropivnitskaya, A. Lindsey, C. and Majumder, D. Mcbrayer, W. Minafra, N. Murray, M. and Rogan, C. Royon, C. Sanders, S. Schmitz, E. Takaki, J. D. Tapia Williams, J. Wilson, G. Duric, S. Ivanov, A. and Kaadze, K. Kim, D. Maravin, Y. Mendis, D. R. and Mitchell, T. Modak, A. Mohammadi, A. Rebassoo, F. and Wright, D. Baden, A. Baron, O. Belloni, A. Eno, S. C. and Feng, Y. Hadley, N. J. Jabeen, S. Jeng, G. Y. and Kellogg, R. G. Kunkle, J. Mignerey, A. C. Nabili, S. and Ricci-Tam, F. Seidel, M. Shin, Y. H. Skuja, A. Tonwar, S. C. Wong, K. Abercrombie, D. Allen, B. Baty, A. and Bi, R. Brandt, S. Busza, W. Cali, I. A. DAlfonso, M. and Ceballos, G. Gomez Goncharov, M. Harris, P. Hsu, D. Hu, M. Klute, M. Kovalskyi, D. Lee, Y-J Luckey, P. D. and Maier, B. Marini, A. C. Mcginn, C. Mironov, C. and Narayanan, S. Niu, X. Paus, C. Rankin, D. Roland, C. and Roland, G. Shi, Z. Stephans, G. S. F. Sumorok, K. Tatar, K. Velicanu, D. Wang, T. W. Wyslouch, B. Benvenuti, A. C. Chatterjee, R. M. Evans, A. Guts, S. Hansen, P. and Hiltbrand, J. Kalafut, S. Kubota, Y. Lesko, Z. Mans, J. and Rusack, R. Wadud, M. A. Acosta, J. G. Oliveros, S. and Bloom, K. Claes, D. R. Fangmeier, C. Finco, L. Golf, F. and Suarez, R. Gonzalez Kamalieddin, R. Kravchenko, I Siado, J. E. Snow, G. R. Stieger, B. Agarwal, G. Harrington, C. and Iashvili, I. Kharchilava, A. Mclean, C. Nguyen, D. and Parker, A. Pekkanen, J. Rappoccio, S. Roozbahani, B. and Alverson, G. Barberis, E. Freer, C. Haddad, Y. and Hortiangtham, A. Madigan, G. Morse, D. M. Orimoto, T. and Skinnari, L. Tishelman-Charny, A. Wamorkar, T. Wang, B. and Wisecarver, A. Wood, D. Bueghly, J. Gunter, T. Hahn, K. A. Odell, N. Schmitt, M. H. Sung, K. Trovato, M. and Velasco, M. Bucci, R. Dev, N. Goldouzian, R. Hildreth, M. Anampa, K. Hurtado Jessop, C. Karmgard, D. J. Lannon, K. Li, W. Loukas, N. Marinelli, N. Mcalister, I and Meng, F. Mueller, C. Musienko, Y. Planer, M. Ruchti, R. and Siddireddy, P. Smith, G. Taroni, S. Wayne, M. and Wightman, A. Wolf, M. Woodard, A. Alimena, J. Bylsma, B. and Durkin, L. S. Flowers, S. Francis, B. Hill, C. Ji, W. Lefeld, A. Ling, T. Y. Winer, B. L. Cooperstein, S. and Dezoort, G. Elmer, P. Hardenbrook, J. Haubrich, N. and Higginbotham, S. Kalogeropoulos, A. Kwan, S. Lange, D. and Lucchini, M. T. Luo, J. Marlow, D. Mei, K. Ojalvo, I and Olsen, J. Palmer, C. Pirou, P. Salfeld-Nebgen, J. and Stickland, D. Tully, C. Norberg, S. Barker, A. Barnes, V. E. Das, S. Gutay, L. Jones, M. Jung, A. W. and Khatiwada, A. Mahakud, B. Miller, D. H. Negro, G. and Neumeister, N. Peng, C. C. Piperov, S. Qiu, H. Schulte, J. F. Sun, J. Wang, F. Xiao, R. Xie, W. Cheng, T. and Dolen, J. Parashar, N. Ecklund, K. M. Freed, S. and Geurts, F. J. M. Kilpatrick, M. Kumar, Arun Padley, B. P. and Redjimi, R. Roberts, J. Rorie, J. Shi, W. Leiton, A. G. Stahl Tu, Z. Zhang, A. Bodek, A. de Barbaro, P. and Demina, R. Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. Garcia-Bellido, A. Han, J. Hindrichs, O. and Khukhunaishvili, A. Ranken, E. Tan, P. Taus, R. and Chiarito, B. Chou, J. P. Gandrakota, A. Gershtein, Y. and Halkiadakis, E. Hart, A. Heindl, M. Hughes, E. Kaplan, S. Kyriacou, S. Laflotte, I Lath, A. Montalvo, R. and Nash, K. Osherson, M. Saka, H. Salur, S. Schnetzer, S. and Sheffield, D. Somalwar, S. Stone, R. Thomas, S. and Thomassen, P. Acharya, H. Delannoy, A. G. Heideman, J. and Riley, G. Spanier, S. Bouhali, O. Celik, A. Dalchenko, M. De Mattia, M. Delgado, A. Dildick, S. Eusebi, R. and Gilmore, J. Huang, T. Kamon, T. Luo, S. Marley, D. and Mueller, R. Overton, D. Pernie, L. Rathjens, D. Safonov, A. Akchurin, N. Damgov, J. De Guio, F. Kunori, S. and Lamichhane, K. Mengke, T. Muthumuni, S. Peltola, T. and Undleeb, S. Volobouev, I Whitbeck, A. Greene, S. and Gurrola, A. Janjam, R. Johns, W. Maguire, C. Melo, A. and Ni, H. Padeken, K. Romeo, F. Sheldon, P. Tuo, S. and Velkovska, J. Verweij, M. Arenton, M. W. Barria, P. Cox, B. Cummings, G. Hirosky, R. Joyce, M. Ledovskoy, A. and Neu, C. Tannenwald, B. Wolfe, E. Xia, F. Harr, R. and Karchin, P. E. Poudyal, N. Sturdy, J. Thapa, P. Zaleski, S. Buchanan, J. Caillol, C. Carlsmith, D. Dasu, S. and De Bruyn, I Dodd, L. Fiori, F. Galloni, C. Gomber, B. and Herndon, M. Herve, A. Hussain, U. Klabbers, P. and Lanaro, A. Loeliger, A. Long, K. Loveless, R. Sreekala, J. Madhusudanan Ruggles, T. Savin, A. Smith, W. H. and Teague, D. Trembath-Reichert, S. Woods, N. CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: A search for decays of the Higgs and Z boson to pairs of J/psi or Y(nS)(n = 1, 2, 3) mesons, with their subsequent decay to mu(+)mu(-) pairs, is presented. The analysis uses data from proton-proton collisions at root s = 13 TeV, collected with the CMS detector at the LHC in 2017 and corresponding to an integrated luminosity of 37.5 fb(-1). While an observation of such a decay with this sample would indicate the presence of physics beyond the standard model, no significant excess is observed. Upper limits at 95% confidence level are placed on the branching fractions of these decays. In the J/psi pair channel, the limits are 1.8 x 10(-3) and 2.2 x 10(-6) for the Higgs and Z boson, respectively, while in the combined Y(nS) pair channel, the limits are 1.4 x 10(-3) and 1.5 x 10(-6), respectively, when the mesons from the Higgs and Z boson decay are assumed to be unpolarized. When fully longitudinal and transverse polarizations are considered the limits reduce by about 22-29% and increase by about 10-13%, respectively. (C) 2019 The Author(s). Published by Elsevier B.V.
Published: 2019

21. Fibrohistiocytic Skin Cancers: Dermatofibrosarcoma Protuberans, Atypical Fibroxanthoma, and Undifferentiated Pleomorphic Sarcoma

Author: Allison Hanlon and Kavita Mariwalla
Subjects: medicine.medical_specialty, Preoperative planning, business.industry, Atypical fibroxanthoma, medicine.disease, Delayed diagnosis, Dermatofibroma, Dermatology, Undifferentiated Pleomorphic Sarcoma, Tissue Stains, Dermatofibrosarcoma protuberans, Medicine, Sarcoma, business
Abstract: As a group, atypical fibroxanthoma, undifferentiated pleomorphic sarcoma, and dermatofibrosarcoma protuberans (DFSP) are rare cutaneous neoplasms with the potential for significant local destruction. In DFSP, delayed diagnosis is common as the clinical presentation can appear benign. Tissue stains are key for diagnosis of dermatofibrosarcoma protuberans from the benign histologic mimicker dermatofibroma. Debate exists regarding the relationship between atypical fibroxanthoma and undifferentiated pleomorphic sarcoma. The preferred treatment for fibrohistiocytic tumors is Mohs micrographic surgery. Since close monitoring for recurrence is critical, repair options for these commonly large postsurgical defects must be carefully planned. In all cases, preoperative planning and management of patient expectation is paramount to successful therapy.
Published: 2018

22. A Practical Guide to Skin Cancer

Author: Allison Hanlon and Allison Hanlon
Subjects: Skin--Cancer--Risk factors, Skin--Cancer, Skin--Cancer--Prevention
Abstract: Skin cancer is the most common malignant neoplasm, and with the increasing regularity of such tumors comes the need for a practical guide for medical professionals to reference for diagnosis, management, and treatment. This book covers everything from the epidemiology of the skin cancer, clinical presentation with clinical photographs, diagrams of the most common anatomical locations, to histological descriptions, special stains/tests for diagnosis, and a treatment algorithm in chart form. A Practical Guide to Skin Cancer offers brief and succinct chapters with pertinent references, as well as high quality color photographs, diagrams, tables, and charts. Written for dermatologists, dermatology residents, and oncologists, this book allows for the reader to quickly and easily obtain the information regarding a tumor's clinical presentation, patient evaluation and treatment algorithms, proving essential for every physician who encounters these tumors in theirdaily practice.
Published: 2018

23. Periocular Melanoma In Situ Treated With Imiquimod

Author: J. Javier Servat, Flora Levin, Maxwell Elia, Carol L. Shields, Jerry A. Shields, Sara E. Lally, Jennifer N. Choi, and Allison Hanlon
Subjects: Male, Chemosis, medicine.medical_specialty, Skin Neoplasms, Administration, Topical, Biopsy, medicine.medical_treatment, Skin Cream, Antineoplastic Agents, Cryotherapy, Imiquimod, Lentigo maligna, Eyelid Neoplasms, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Canthus, Melanoma, Aged, Retrospective Studies, medicine.diagnostic_test, business.industry, Eyelids, Ectropion, General Medicine, medicine.disease, Dermatology, eye diseases, Surgery, body regions, Ophthalmology, Treatment Outcome, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Aminoquinolines, Female, Eyelid, medicine.symptom, business, medicine.drug
Abstract: PURPOSE To evaluate the efficacy of topical 5% imiquimod cream in the treatment of periocular melanoma in situ (lentigo maligna). DESIGN Retrospective case series. SUBJECTS There were 12 patients in this series, and the mean patient age was 77 years. The anatomical locations were the lower eyelid (n=5), upper and lower eyelid (n=4), lower eyelid including the eyelid margin (n=1), brow (n=1), and the medial canthus (n=1). Topical 5% imiquimod cream was used as a primary treatment (n=6) or as an adjunctive therapy following local excision (n=2), cryotherapy (n=2), or excisional biopsy with cryotherapy (n=2). METHODS Twelve patients with periocular melanoma in situ were treated with topical 5% imiquimod cream daily for a mean treatment period of 3.9 months. The clinical features of the patients and the responses to treatment were evaluated in a retrospective case series. MAIN OUTCOME MEASURES Histologic clearance of atypical melanocytes. RESULTS Eleven patients achieved complete histologic clearance of atypical melanocytes on post-treatment biopsy. One patient could not tolerate local irritation from imiquimod and stopped in the first month of therapy with residual disease. The median follow-up time was 1.5 years. Side effects included redness (n=12), discomfort (n=6), swelling (n=4), ectropion (n=1), and conjunctival chemosis (n=1). The patients experienced no systemic side effects from the treatment. CONCLUSIONS Topical 5% imiquimod cream is an effective option as primary or adjunct therapy in the treatment of periocular melanoma in situ.
Published: 2016

24. The Cutting Edge of Skin Cancer in Transplant Recipients: Scientific Retreat of International Transplant Skin Cancer Collaborative and Skin Cancer in Organ Transplant Patients Europe

Author: Oscar R. Colegio and Allison Hanlon
Subjects: Research Report, Societies, Scientific, medicine.medical_specialty, Skin Neoplasms, Article, Organ transplantation, Humans, Immunology and Allergy, Medicine, Pharmacology (medical), Cooperative Behavior, Intensive care medicine, Transplantation, integumentary system, business.industry, International Agencies, Organ Transplantation, medicine.disease, Transplant Recipients, Surgery, Europe, surgical procedures, operative, Increased risk, Transplant patient, Cooperative behavior, Skin cancer, business, Solid organ transplantation
Abstract: The International Transplant Skin Cancer Collaborative (ITSCC) is an organization of more than 300 physicians and scientists focused on the study of dermatologic changes following solid organ transplantation. Transplant patients have a 100-fold increased risk of developing skin cancer. In October 2012, ITSCC and its European counterpart Skin Cancer in Organ Transplant Patients Europe held a joint biennial retreat in Essex, MA to discuss novel findings in the pathogenesis and management of skin cancer in solid organ transplant recipients. This meeting report is a summary of the novel findings discussed.
Published: 2014

25. 280 Validation of algorithms to identify transplant recipients from the electronic health record

Author: Nimay Anand, Allison Hanlon, Lee Wheless, Kelly A. Birdwell, Mary-Margaret Chren, L.D. Edwards, and L. Wang
Subjects: Electronic health record, Computer science, medicine, Cell Biology, Dermatology, Medical emergency, medicine.disease, Molecular Biology, Biochemistry
Published: 2019

26. Metastatic Squamous Cell Carcinoma: Epidemiology and Available Systemic Therapies

Author: Allison Hanlon
Subjects: Oncology, medicine.medical_specialty, Cutaneous squamous cell carcinoma, Squamous cell cancer, business.industry, Dermatology, medicine.disease, Therapeutic trial, Primary tumor, Metastasis, stomatognathic diseases, Internal medicine, Epidemiology, medicine, Basal cell, business, EGFR inhibitors
Abstract: Metastatic cutaneous squamous cell carcinoma rarely since surgery cures the majority of primary tumors. Metastatic cutaneous squamous cell carcinoma causes significant morbidity and mortality. Identifying characteristics of patients and the primary tumor may help to predict risk for metastasis and aid in the prevention, detection, or treatment of metastatic squamous cell cancer. Due to the rarity of metastatic cutaneous SCC, there are few prospective trials examining tumor characteristics associated with metastasis. Furthermore, the rarity and morbidity of metastatic squamous cell carcinoma make randomized controlled therapeutic trials difficult. We examine the risk factors and systemic treatments for metastatic cutaneous squamous cell carcinoma.
Published: 2013

27. Intralesional interferon alfa-2b for refractory, recurrent squamous cell carcinoma of the face

Author: Allison Hanlon, David J. Leffell, and June Kim
Subjects: medicine.medical_specialty, Refractory, business.industry, medicine, Recurrent squamous cell carcinoma, Dermatology, business, Interferon alfa, medicine.drug
Published: 2013

28. Histopathologic assessment of depth of follicular invasion of squamous cell carcinoma (SCC) in situ (SCCis): Implications for treatment approach

Author: Jennifer M. McNiff, Sean R. Christensen, David J. Leffell, Alicia J. Cool, Allison Hanlon, and Sumaira Z. Aasi
Subjects: Sebaceous gland, Pathology, medicine.medical_specialty, Skin Neoplasms, medicine.medical_treatment, Dermatology, 030207 dermatology & venereal diseases, 03 medical and health sciences, Follicle, 0302 clinical medicine, Follicular phase, Mohs surgery, medicine, Humans, Neoplasm Invasiveness, Retrospective Studies, Epidermis (botany), business.industry, Carcinoma in situ, Histology, Hair follicle, medicine.disease, Mohs Surgery, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, business, Hair Follicle, Carcinoma in Situ
Abstract: Background Squamous cell carcinoma in situ (SCCis) has been reported to involve the hair follicle epithelium. Deep follicular invasion is often cited as a cause of treatment failure. Objective We sought to define the frequency and the depth of hair follicle invasion by SCCis. Methods The study included both a retrospective review of intraoperative pathology specimens from 42 SCCis cases treated with Mohs micrographic surgery and a prospective evaluation of serially sectioned SCCis tissue from 12 additional patients. Pathology specimens were analyzed for follicular invasion of SCCis. Results SCCis invasion of the superficial hair follicle infundibulum was observed in 61.3% to 87.5% of cases in the 2 cohorts, whereas invasion of the isthmus and lower follicle was observed in only 8.3% to 12.5% of cases. In most tumors the depth of follicular invasion was comparable with the thickness of the surrounding epidermis. The maximum observed depth of follicular invasion was 0.82 mm. Limitations The study was performed on a limited number of cases referred for surgery at a single institution. Conclusions Although SCCis invasion of the upper hair follicle infundibulum is common, deep invasion below the level of the surrounding epidermis is rare. This may have implications for optimal therapy of this condition.
Published: 2015

29. Mohs Micrographic Surgery for Cutaneous Lymphadenoma

Author: Thomas Stasko, Allison Hanlon, and Anna S. Clayton
Subjects: Adult, Male, medicine.medical_specialty, Skin Neoplasms, medicine.medical_treatment, Dermatology, Micrographic surgery, Cutaneous lymphadenoma, medicine, Mohs surgery, Humans, Basal cell carcinoma, Head and neck, Aged, 80 and over, business.industry, Treatment options, General Medicine, Adenolymphoma, Mohs Surgery, medicine.disease, Surgery, Female, Surgical excision, Facial Neoplasms, business
Abstract: Cutaneous lymphadenoma clinically present as pink papules or plaques resembling a basal cell carcinoma on the head and neck of young adults. Surgical excision is the treatment for these benign tumors. Cutaneous lymphadenoma may occur in an anatomically sensitive area, where margin control and conservative excision are indicated. Although not previously described in the literature, Mohs micrographic surgery (MMS) is a treatment option for cutaneous lymphadenoma. We present a series of three individuals with cutaneous lymphadenoma treated with MMS.
Published: 2012

30. Phosphatidylinositol 3′-Kinase Blocks CD95 Aggregation and Caspase-8 Cleavage at the Death-Inducing Signaling Complex by Modulating Lateral Diffusion of CD95

Author: Peter H. Krammer, Allison Hanlon, Michael Edidin, Padmini Salgame, Marcus E. Peter, and Arun S. Varadhachary
Subjects: Fas-Associated Death Domain Protein, T-Lymphocytes, Immunology, Apoptosis, Caspase 8, Diffusion, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, hemic and lymphatic diseases, Humans, Immunology and Allergy, fas Receptor, Phosphatidylinositol, Cytoskeleton, Adaptor Proteins, Signal Transducing, Cytochalasin D, Caspase-9, biology, Kinase, Hydrolysis, Cell Membrane, Receptor Aggregation, Fas receptor, Actin cytoskeleton, Caspase Inhibitors, Actins, Caspase 9, Clone Cells, Cell biology, chemistry, Caspases, Death-inducing signaling complex, biology.protein, biological phenomena, cell phenomena, and immunity, Carrier Proteins, Signal Transduction
Abstract: Activation of phosphatidylinositol 3′-kinase (PI 3′-K) after ligation of CD3 protects Th2 cells from CD95-mediated apoptosis. Here we show that protection is achieved by inhibition of the formation of CD95 aggregates and consequent activation of caspase-8. Inhibition of aggregate formation is mediated by changes in the actin cytoskeleton, which in turn inhibit lateral diffusion of CD95, reducing its diffusion coefficient, D, 10-fold. After cytochalasin D treatment of stimulated cells, the lateral diffusion of CD95 increases to the value measured on unstimulated cells, and CD95 molecules aggregate to process caspase-8 and mediate apoptosis. Regulation of functional receptor formation by modulating lateral diffusion is a novel mechanism for controlling receptor activity.
Published: 2001

31. Gene expression profiling for cardiac rejection surveillance is not predictive of post-transplantation skin cancer

Author: Allison, Hanlon, Megan, O'Neill, Fiona, Fang, Heidi, Chen, Jason, Lott, Mark, Wigger, and Thomas, Stasko
Subjects: Adult, Graft Rejection, Immunosuppression Therapy, Skin Neoplasms, Gene Expression Profiling, Myocardium, Gene Expression, Middle Aged, Predictive Value of Tests, Azathioprine, Carcinoma, Squamous Cell, Leukocytes, Mononuclear, Heart Transplantation, Humans, Immunosuppressive Agents, Aged, Retrospective Studies
Abstract: The risk of skin cancer in solid organ transplant recipients (SOTR) is 50 to 100 times as great as in those without a transplant. Multiple factors, including immunosuppression, influence the development of post-transplantation skin cancer. Individuals with cardiac transplant are serially screened for organ rejection and immunosuppressive regimen effectiveness. Gene expression profiling of peripheral blood mononuclear cells has been established as a noninvasive test for monitoring cardiac rejection.We examined individuals with cardiac transplant monitored using peripheral gene expression profiling to determine whether the profile of peripheral blood mononuclear cell activity could correlate with the development of post-transplantation skin cancer.Sixty-one patient records were examined for initial endomyocardial biopsy results, gene expression profiling data, immunosuppressive regimens, and post-transplantation skin cancer.There was no relationship between acute rejection and the development of skin cancer. No relationship between peripheral gene expression profiling and the development of post-transplantation skin cancer was observed. The most common skin cancer in the population was squamous cell carcinoma. SOTR suppressed with azathioprine had a significantly higher incidence of squamous cell carcinoma.Although gene expression tests have advanced transplant surveillance, they were not associated with post-transplantation skin cancer.
Published: 2013

32. Melanoma and nevi: detection and diagnosis

Author: Allison Hanlon, Jennifer N. Choi, and David J. Leffell
Subjects: Cancer Research, medicine.medical_specialty, Skin Neoplasms, business.industry, Melanoma, Age Factors, medicine.disease, Dermatology, Hutchinson's Melanotic Freckle, Early Diagnosis, Oncology, Risk Factors, Medicine, Humans, business, Nevus
Published: 2011

33. Correlation of Global MicroRNA Expression With Basal Cell Carcinoma Subtype

Author: Allison Hanlon, Patricia B. Gordon, Zhengqing Ouyang, Christopher Heffelfinger, Michael Snyder, Wei Zheng, Allen E. Bale, David J. Leffell, Anna K. Engberg, and Hongyu Zhao
Subjects: medicine.medical_specialty, Pathology, Biology, Investigations, Metastasis, 03 medical and health sciences, 0302 clinical medicine, miR-150, microRNA, Genetics, medicine, Basal cell carcinoma, Molecular Biology, Genetics (clinical), 030304 developmental biology, 0303 health sciences, skin cancer, medicine.disease, 3. Good health, Gene expression profiling, Real-time polymerase chain reaction, miR-183, expression profiling, 030220 oncology & carcinogenesis, Immunology, histopathology, Histopathology, Skin cancer
Abstract: Basal cell carcinomas (BCCs) are the most common cancers in the United States. The histologic appearance distinguishes several subtypes, each of which can have a different biologic behavior. In this study, global miRNA expression was quantified by high-throughput sequencing in nodular BCCs, a subtype that is slow growing, and infiltrative BCCs, aggressive tumors that extend through the dermis and invade structures such as cutaneous nerves. Principal components analysis correctly classified seven of eight infiltrative tumors on the basis of miRNA expression. The remaining tumor, on pathology review, contained a mixture of nodular and infiltrative elements. Nodular tumors did not cluster tightly, likely reflecting broader histopathologic diversity in this class, but trended toward forming a group separate from infiltrative BCCs. Quantitative polymerase chain reaction assays were developed for six of the miRNAs that showed significant differences between the BCC subtypes, and five of these six were validated in a replication set of four infiltrative and three nodular tumors. The expression level of miR-183, a miRNA that inhibits invasion and metastasis in several types of malignancies, was consistently lower in infiltrative than nodular tumors and could be one element underlying the difference in invasiveness. These results represent the first miRNA profiling study in BCCs and demonstrate that miRNA gene expression may be involved in tumor pathogenesis and particularly in determining the aggressiveness of these malignancies.
Published: 2011

34. Management of Skin Cancer in the Immunocompromised Patient

Author: Thomas Stasko, Allison Hanlon, and Anna S. Clayton
Subjects: medicine.medical_specialty, business.industry, medicine, Immunocompromised patient, Skin cancer, medicine.disease, business, Dermatology
Published: 2011

35. List of Contributors

Author: Verena Ahlgrimm-Siess, Samuel Fehring Almquist, Sadegh Amini, Robert H.I. Andtbacka, Diana D. Antonovich, Jack L. Arbiser, Donald Baumann, Brian Berman, Ricardo L. Berrios, Avani Bhambri, Sanjay Bhambri, Jean L. Bolognia, Tawnya L. Bowles, Marc David Brown, Christopher T. Burnett, Phyllis Nancy Butow, Jeffrey P. Callen, John A. Carucci, Jennifer Clay Cather, Roger I. Ceilley, Lorenzo Cerroni, Jason Chang, Suephy C. Chen, Melissa Chiang, Anna Sancho Clayton, Clay J. Cockerell, Oscar R. Colegio, Sallyann M. Coleman King, Jay S. Cooper, Clara Curiel-Lewandowski, James Q. Del Rosso, The late Marie-France Demierre, Scott Dinehart, Marcia S. Driscoll, Melody J. Eide, Dirk M. Elston, Jo-David Fine, Robert J. Friedman, Jeffrey E. Gershenwald, Kathryn A. Gold, Jacqueline M. Goulart, Jane M. Grant-Kels, Joan Guitart, Luke Hall-Jordan, Allan C. Halpern, Allison Hanlon, Edward Heilman, Rainer Hofmann-Wellenhof, Drusilla Hufford, Sherrif F. Ibrahim, Jayasri G. Iyer, S. Brian Jiang, Holly Kanavy, Nadine Angele Kasparian, Helmut Kerl, Merrill S. Kies, John M. Kirkwood, Rebecca Kleinerman, Wendy Kohlmann, Michael Krathen, Mario E. Lacouture, Pearon G. Lang, Alexander J. Lazar, Sancy Leachman, Philip E. LeBoit, Peter J. Lebovitz, Mark G. Lebwohl, Ken K. Lee, David J. Leffell, Justin J. Leitenberger, Henry W. Lim, John C. Maize, Ashfaq A. Marghoob, Beth McLellan, Michael K. Miller, Kriti Mohan, Colin A. Morton, Stergios J. Moschos, Luigi Naldi, Paul Nghiem, Tanya Nino, Gagik Oganesyan, Margaret C. Oliviero, Seth J. Orlow, Patrick A. Ott, Amit G. Pandya, Paola Pasquali, Anna C. Pavlick, Shari Pilon-Thomas, David Polsky, Harper N. Price, Abrar A. Qureshi, Harold S. Rabinovitz, Luis Requena, Carlos Ricotti, Darrell S. Rigel, Caroline Robert, June K. Robinson, Theodore Rosen, Merrick Ross, Julie E. Russak, Justin M. Sacks, Miguel Sanchez, Omar P. Sangueza, Daniel J. Santa Cruz, Amod A. Sarnaik, Courtney R. Schadt, Julie V. Schaffer, Alon Scope, Joseph F. Sobanko, Vernon K. Sondak, James M. Spencer, Thomas Stasko, Jennifer Stein, Eggert Stockfleth, Jamison Strahan, Neil A. Swanson, Ahmad Tarhini, Hussein Tawbi, R. Stan Taylor, Renee Thibodeau, Bruce H. Thiers, Emily Tierney, Abel Torres, Kien T. Tran, Edward Upjohn, Whitney Elizabeth Valins, Martha H. Viera, Nasreen Vohra, William Wachsman, Sarah N. Walsh, Steven Q. Wang, Christina L. Warner, Allison Weinkle, Martin A. Weinstock, J. Michael Wentzell, Victoria Williams, Oliver J. Wisco, William K. Witmer, Wenfei Xie, and Brittany A. Zwischenberger
Published: 2011

36. Sirolimus Reduces Cutaneous Squamous Cell Carcinomas in Transplantation Recipients

Author: Oscar R. Colegio, John A. Carucci, Allison Hanlon, and Edit Olasz
Subjects: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Cell, MEDLINE, medicine.disease, Transplantation, Text mining, medicine.anatomical_structure, Sirolimus, Internal medicine, Carcinoma, Medicine, business, medicine.drug
Published: 2013

37. Use of imiquimod for residual acral melanoma

Author: Allison Hanlon, Gloria R. Sue, Deepak Narayan, and Rossitza Lazova
Subjects: Male, medicine.medical_specialty, Skin Neoplasms, Skin Cream, Plantar surface, Antineoplastic Agents, Imiquimod, Administration, Cutaneous, Article, Foot Diseases, medicine, Humans, Effective treatment, Melanoma, neoplasms, Aged, 80 and over, Repeat biopsy, business.industry, General Medicine, medicine.disease, Dermatology, Surgery, Treatment Outcome, Acral melanoma, Aminoquinolines, Female, Topical imiquimod, business, Carcinoma in Situ, Follow-Up Studies, medicine.drug
Abstract: Recent reports suggest that topical imiquimod cream is an effective treatment option for certain types of melanomas. No reports exist on the efficacy of using imiquimod cream to treat melanoma located on the plantar surface of the foot. We present two patients with a melanoma of the foot who had residual melanoma following surgical excision with acceptable margins. The patients were then treated with topical imiquimod for 8 weeks after which a repeat biopsy of the affected region showed no evidence of residual melanoma in situ. The use of topical imiquimod cream should be considered in the management of residual melanoma in situ of the plantar surface of the foot.
Published: 2014

38. Cbl-b differentially regulates activation-induced apoptosis in T helper 1 and T helper 2 cells

Author: Padmini Salgame, Sihyug Jang, and Allison Hanlon
Subjects: CD3 Complex, CD3, Immunology, Apoptosis, Biology, Mice, Interleukin 21, Membrane Microdomains, Th2 Cells, hemic and lymphatic diseases, Animals, Immunology and Allergy, Cytotoxic T cell, Proto-Oncogene Proteins c-cbl, Actin, Adaptor Proteins, Signal Transducing, Microscopy, Confocal, CD40, CD28, Original Articles, Th1 Cells, Actins, Cell biology, Mice, Inbred C57BL, biology.protein, Female, Signal transduction, Signal Transduction
Abstract: We previously reported that ligation of CD3 induces antiapoptotic signals in T helper 2 (Th2) cells, and in contrast causes Th1 cells to undergo apoptosis. Here we show that Cbl-b is accountable for the unequal response, revealing a previously unknown cell-specific regulatory function for the molecule. Absence of Cbl-b resulted in resistance to activation-induced apoptosis in murine Th1 cells following CD3 ligation, akin to what is observed in Th2 cells containing Cbl-b. Concurrent with the apoptosis profile, CD3 ligation in the absence of Cbl-b induced raft mobilization and cytoskeletal rearrangement in Th1 cells. Despite their ability to signal from CD3, Th2 cells did not aggregate their rafts, providing an explanation for cell-specific activity of Cbl-b.
Published: 2005

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