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1. Stable Isotope Tracing In Vivo Reveals A Metabolic Bridge Linking The Microbiota To Host Histone Acetylation

2. Interview with C. David Allis, PhD

3. In Vivo Cross-Linking and Immunoprecipitation for Studying Dynamic Protein:DNA Associations in a Chromatin Environment

4. Excision of micronuclear-specific DNA requires parental expression of Pdd2p andoccursindependentlyfromDNA replication in Tetrahymena thermophila

5. Preface

6. Identification of a Novel Polypeptide Involved in the Formation of DNA-Containing Vesicles during Macronuclear Development in Tetrahymena

7. Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

9. Histone phosphorylation in macro- and micronuclei of Tetrahymena thermophila

10. RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction

11. Epigenetics of ciliates

13. Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation.

14. Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression.

15. Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055.

16. Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation.

17. MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.

19. Histone bivalency regulates the timing of cerebellar granule cell development.

20. MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer.

21. A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.

22. Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation.

23. Histone H1 Mutations in Lymphoma: A Link(er) between Chromatin Organization, Developmental Reprogramming, and Cancer.

24. Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.

25. The language of chromatin modification in human cancers.

26. A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies.

27. Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.

28. Oncohistone mutations enhance chromatin remodeling and alter cell fates.

29. Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.

30. Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.

31. HAT discovery: Heading toward an elusive goal with a key biological assist.

32. HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies.

33. Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.

34. Epigenomic Reprogramming as a Driver of Malignant Glioma.

35. Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.

36. Loss of UTX/KDM6A and the activation of FGFR3 converge to regulate differentiation gene-expression programs in bladder cancer.

37. The epigenomics of sarcoma.

38. Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.

39. Histone H3.3 phosphorylation amplifies stimulation-induced transcription.

40. In situ chromatin interactomics using a chemical bait and trap approach.

41. Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.

42. ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.

43. Impaired cell fate through gain-of-function mutations in a chromatin reader.

44. Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism.

45. PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.

46. The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.

47. Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.

48. Target identification reveals lanosterol synthase as a vulnerability in glioma.

49. The expanding landscape of 'oncohistone' mutations in human cancers.

50. Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking.

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