124 results on '"Allentoff, Alban"'
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2. Synthesis of an adenine N-3 substituted CBI adduct by alkylation of adenine with a 1-iodomethylindoline seco-CBI precursor
3. Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form
4. Quantitation of a PEGylated protein in monkey serum by UHPLC-HRMS using a surrogate disulfide-containing peptide: A new approach to bioanalysis and in vivo stability evaluation of disulfide-rich protein therapeutics
5. Utilizing Internal Standard Responses to Assess Risk on Reporting Bioanalytical Results from Hemolyzed Samples
6. Development and validation of an LC–MS/MS assay for the quantitation of a PEGylated anti-CD28 domain antibody in human serum: overcoming interference from antidrug antibodies and soluble target
7. Understanding the cellular uptake of phosphopeptides
8. Comparisons of hydroperoxide isomerase and monooxygenase activities of cytochrome P450 for conversions of allylic hydroperoxides and alcohols to epoxyalcohols and diols: probing substrate reorientation in the active site
9. Chemoselective Methionine Bioconjugation: Site-Selective Fluorine-18 Labeling of Proteins and Peptides
10. Heterolytic versus homolytic peroxide bond cleavage by sperm whale myoglobin and myoglobin mutants
11. Determination of Real Time in Vivo Drug Receptor Occupancy for a Covalent Binding Drug as a Clinical Pharmacodynamic Biomarker by Immunocapture-LC-MS/MS
12. Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton’s Tyrosine Kinase (BTK)
13. Direct Carbon Isotope Exchange through Decarboxylative Carboxylation
14. Direct Carbon Isotope Exchange Through Decarboxylative Carboxylation
15. Adnectin–drug conjugates for Glypican-3-specific delivery of a cytotoxic payload to tumors
16. Synthesis of 2-14C-iminothiolane and 2-13C,15N-iminothiolane (Traut's reagent)
17. Synthesis of a stable isotopically labeled universal surrogate peptide for use as an internal standard in LC‐MS/MS bioanalysis of human IgG and Fc‐fusion protein drug candidates
18. Innovative Use of LC-MS/MS for Simultaneous Quantitation of Neutralizing Antibody, Residual Drug, and Human Immunoglobulin G in Immunogenicity Assay Development
19. Fully Validated LC-MS/MS Assay for the Simultaneous Quantitation of Coadministered Therapeutic Antibodies in Cynomolgus Monkey Serum
20. Synthesis of acyl[35S]sulfonamides: Coupling of high specific activity [35S]methane sulfonamide with acids and acid chlorides
21. Cytochrome P450 11A1 Bioactivation of a Kinase Inhibitor in Rats: Use of Radioprofiling, Modulation of Metabolism, and Adrenocortical Cell Lines to Evaluate Adrenal Toxicity
22. The 14C, 13C, and 15N syntheses of a potent VEGFR-2 kinase inhibitor, Brivanib, and its prodrug, Brivanib Alaninate
23. Metabolism and Disposition of [14C]Brivanib Alaninate after Oral Administration to Rats, Monkeys, and Humans
24. Metabolism and Disposition of [14C]BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor, after Oral Administration to Humans
25. Metabolism and Disposition of [14C]BMS-690514 after Oral Administration to Rats, Rabbits, and Dogs
26. Metabolism and Disposition of Dasatinib after Oral Administration to Humans
27. Synthesis of14C-labeled and13C-,15N-labeled dasatinib and its piperazineN-dealkyl metabolite
28. Convenient and efficient tritiation of aristolochic acid I (AAI) and aristolochic acid II (AAII) with tritiated water
29. Synthesis and analysis of tritiated camptothecin analogs with iridium-mediated3H exchange
30. Synthesis and analysis of [3H] salmon calcitonin ([3H]SMC021)
31. Synthesis of radio- and stable-labelled LAF237(Galvus, Vildagliptin)
32. Synthesis of 2-14C-iminothiolane and 2-13C,15N-iminothiolane (Traut's reagent).
33. Synthesis of radio- and stable-labelled Fasidotril
34. Palladium-catalyzed aryl cyanations with [14C]KCN: Synthesis of14C-labelled fadrozole, a potent aromatase inhibitor
35. Innovative Use of LC-MS/MS for Simultaneous Quantitation of Neutralizing Antibody, Residual Drug, and Human Immunoglobulin G in Immunogenicity Assay Development.
36. Synthesis of 14C-labelled CGS 16949A (Fadrozole HCl), a potent aromatase inhibitor
37. Synthesis of 14C-labelled CGS 19755, a selective NMDA antagonist
38. Fully Validated LC-MS/MS Assay for the Simultaneous Quantitation of Coadministered Therapeutic Antibodies in Cynomolgus Monkey Serum.
39. The.
40. Synthesis of the bicyclo[5.3.1]undecane moiety (AB ring system) of taxanes
41. Synthesis of 14C-labeled and 13C-,15N-labeled dasatinib and its piperazine N-dealkyl metabolite.
42. Synthesis and analysis of tritiated camptothecin analogs with iridium-mediated 3H exchange.
43. Intramolecular [2 + 2]cycloadditions of dialkylketenes with alkenes. Regiochemistry of intramolecular [2+2]cycloadditions of ketenes with alkenes
44. Palladium-catalyzed aryl cyanations with [14C]KCN: Synthesis of 14C-labelled fadrozole, a potent aromatase inhibitor.
45. Synthesis of 14C-labelled CGS 16949A (Fadrozole HCl), a potent aromatase inhibitor.
46. Synthesis of 14C-labelled CGS 19755, a selective NMDA antagonist.
47. Synthesis of 14C‐labeled and 13C‐,15N‐labeled dasatinib and its piperazine N‐dealkyl metabolite
48. Synthesis and analysis of tritiated camptothecin analogs with iridium‐mediated 3H exchangeProceedings of the Ninth International Symposium on the Synthesis and Applications of Isotopically Labelled Compounds, Edinburgh, 16–20 July 2006.
49. Palladium-catalyzed aryl cyanations with [<SUP>14</SUP>C]KCN: Synthesis of <SUP>14</SUP>C-labelled fadrozole, a potent aromatase inhibitor
50. Synthesis of acyl[35S]sulfonamides: Coupling of high specific activity [35S]methane sulfonamide with acids and acid chlorides.
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